HUT42486A - Process for producing carbapeneme derivatives containing quaternerized hetero-thio-alkyl-thio substituent at the 2-position - Google Patents

Process for producing carbapeneme derivatives containing quaternerized hetero-thio-alkyl-thio substituent at the 2-position

Info

Publication number
HUT42486A
HUT42486A HU864830A HU483086A HUT42486A HU T42486 A HUT42486 A HU T42486A HU 864830 A HU864830 A HU 864830A HU 483086 A HU483086 A HU 483086A HU T42486 A HUT42486 A HU T42486A
Authority
HU
Hungary
Prior art keywords
thio
quaternerized
hetero
alkyl
producing
Prior art date
Application number
HU864830A
Other languages
English (en)
Other versions
HU197748B (en
Inventor
Pierre Dextraze
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of HUT42486A publication Critical patent/HUT42486A/hu
Publication of HU197748B publication Critical patent/HU197748B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HU864830A 1985-11-22 1986-11-21 Process for producing carbapenem derivatives substituted at the 2-position by quaternizated pyridylthioalkylthio group and pharmaceuticals comprising same as active ingredient HU197748B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/800,867 US4880922A (en) 1985-11-22 1985-11-22 Carbapenems with quaternized heterothioalkylthio substitution at position 2

Publications (2)

Publication Number Publication Date
HUT42486A true HUT42486A (en) 1987-07-28
HU197748B HU197748B (en) 1989-05-29

Family

ID=25179586

Family Applications (1)

Application Number Title Priority Date Filing Date
HU864830A HU197748B (en) 1985-11-22 1986-11-21 Process for producing carbapenem derivatives substituted at the 2-position by quaternizated pyridylthioalkylthio group and pharmaceuticals comprising same as active ingredient

Country Status (35)

Country Link
US (1) US4880922A (hu)
JP (1) JPS62195382A (hu)
KR (1) KR870004985A (hu)
CN (1) CN86107742A (hu)
AR (1) AR242209A1 (hu)
AT (1) AT397090B (hu)
AU (1) AU598767B2 (hu)
BE (1) BE905801A (hu)
CA (1) CA1273015A (hu)
CH (1) CH671020A5 (hu)
CS (1) CS259895B2 (hu)
DD (1) DD250710A5 (hu)
DE (1) DE3639762A1 (hu)
DK (1) DK560886A (hu)
EG (1) EG18111A (hu)
ES (1) ES2002914A6 (hu)
FI (1) FI83323C (hu)
FR (1) FR2590574B1 (hu)
GB (1) GB2183237B (hu)
GR (1) GR862786B (hu)
HU (1) HU197748B (hu)
IL (1) IL80694A0 (hu)
IT (1) IT1199669B (hu)
LU (1) LU86678A1 (hu)
MY (1) MY102954A (hu)
NL (1) NL8602964A (hu)
NO (1) NO164239C (hu)
NZ (1) NZ218296A (hu)
OA (1) OA08488A (hu)
PT (1) PT83797B (hu)
SE (1) SE469631B (hu)
SU (1) SU1614763A3 (hu)
YU (1) YU46030B (hu)
ZA (1) ZA868829B (hu)
ZW (1) ZW23486A1 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219892A (en) * 1986-04-15 1991-02-26 Merck & Co Inc N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof
US5116833A (en) * 1990-10-19 1992-05-26 Bristol-Myers Squibb Company Antibiotic c-3 dithioacetal-substituted carbapenem compounds, compositions, and methods of use thereof
CA2065079C (en) * 1991-04-05 2003-03-18 Michiyuki Sendai Polycyclic carbapenem compounds, their production and use
FR2920778B1 (fr) 2007-09-11 2009-10-30 Oreal Composes quinoliniums azoiques a motif disulfure/thiol, compositions les comprenant, procede de coloration de fibres keratiniques et dispositif.
FR2921382B1 (fr) 2007-09-21 2009-10-30 Oreal Colorant derive de phenyl-pyridol[1,2-a]indolium thiol-disulfure, composition tinctoriale comprenant ce colorant, procede d'eclaircissement des matieres keratiniques a partir de ce colorant
FR2921258A1 (fr) * 2007-09-24 2009-03-27 Oreal Composition tinctoriale comprenant au moins un precurseur incolore disulfures/thiol, proced de coloration a partir de la composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376774A (en) * 1979-05-29 1983-03-15 Merck & Co., Inc. Antibiotic N-heterocyclyl thienamycin
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
CA1269978A (en) * 1982-09-28 1990-06-05 Choung U. Kim Carbapenem antibiotics
DK140584A (da) * 1983-03-08 1984-09-09 Bristol Myers Co Fremgangsmaade til fremstilling af carbapenemderivater
CA1273011A (en) * 1984-07-02 1990-08-21 Susan M. Schmitt Carbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkylthio substituent
CA1273012A (en) * 1984-07-02 1990-08-21 Burton G. Christensen 1-methylcarbapenems having an externally alkylated mono- of bicyclic 2-quarternary heteroarylalkylthio substituent
NZ219892A (en) * 1986-04-15 1991-02-26 Merck & Co Inc N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
CA1273015A (en) 1990-08-21
FI864714A (fi) 1987-05-23
YU46030B (sh) 1992-12-21
BE905801A (fr) 1987-05-21
US4880922A (en) 1989-11-14
IT1199669B (it) 1988-12-30
GB2183237A (en) 1987-06-03
ATA313686A (de) 1993-06-15
FI864714A0 (fi) 1986-11-19
GB8627913D0 (en) 1986-12-31
AU598767B2 (en) 1990-07-05
NO864669D0 (no) 1986-11-21
NO864669L (no) 1987-05-25
CS843186A2 (en) 1988-03-15
AU6534386A (en) 1987-05-28
IT8622426A0 (it) 1986-11-21
ZW23486A1 (en) 1987-04-29
JPS62195382A (ja) 1987-08-28
AR242209A1 (es) 1993-03-31
YU199486A (en) 1988-02-29
OA08488A (fr) 1988-07-29
CN86107742A (zh) 1987-08-12
SE469631B (sv) 1993-08-09
SE8604990L (sv) 1987-05-23
IT8622426A1 (it) 1988-05-21
DD250710A5 (de) 1987-10-21
IL80694A0 (en) 1987-02-27
SE8604990D0 (sv) 1986-11-21
PT83797B (pt) 1989-06-30
NL8602964A (nl) 1987-06-16
EG18111A (en) 1992-09-30
AT397090B (de) 1994-01-25
NZ218296A (en) 1990-04-26
FI83323C (fi) 1991-06-25
NO164239B (no) 1990-06-05
GR862786B (en) 1987-03-24
DE3639762A1 (de) 1987-06-04
CS259895B2 (en) 1988-11-15
LU86678A1 (fr) 1987-06-26
KR870004985A (ko) 1987-06-04
ZA868829B (en) 1987-08-26
FI83323B (fi) 1991-03-15
FR2590574B1 (fr) 1989-07-28
DK560886A (da) 1987-05-23
FR2590574A1 (fr) 1987-05-29
SU1614763A3 (ru) 1990-12-15
HU197748B (en) 1989-05-29
PT83797A (en) 1986-12-01
DK560886D0 (da) 1986-11-21
ES2002914A6 (es) 1988-10-01
NO164239C (no) 1990-09-12
CH671020A5 (hu) 1989-07-31
MY102954A (en) 1993-03-31
GB2183237B (en) 1989-11-08

Similar Documents

Publication Publication Date Title
YU116787A (en) Process for obtaining imidazochynolinic derivatives
HUT41775A (en) Process for producing new thiazolidinedione derivatives
YU183586A (en) Process for obtaining chynoline derivatives
PT81000A (en) Process for the preparation of heterocyclic derivatives
HUT40454A (en) Process for preparing 4-substituted androstene-dione derivatives
HUT44530A (en) Process for producing furanon derivatives
YU126787A (en) Process for obtaining 9a-aza-9a-homoeritromicyn derivatives
HU904110D0 (en) Process for producing pyrimidine derivatives
HUT42441A (en) Process for preparing indolyl- and indazolyl-carboxamide derivatives
GR861841B (en) Process for the preparation of poly-4-aminopyrrole-2-carboxamido derivatives
YU210187A (en) Process for obtaining imidazolylalkylguanidinic derivatives
HUT41768A (en) Process for producing diphenyl-piperidine derivatives
HUT42500A (en) New process for preparing sphyngosine derivatives
GR860382B (en) Process for the preparation of heterocyclic derivatives
HUT41766A (en) Process for producing benzimidazol derivatives
HUT44501A (en) Process for producing dihydr-pyridine derivatives
HUT42486A (en) Process for producing carbapeneme derivatives containing quaternerized hetero-thio-alkyl-thio substituent at the 2-position
PT80336A (en) Process for the iminothiazolidine derivatives
HUT43617A (en) Process for producing gonatriene derivatives
PT83884A (en) Process for the preparation of 1 azolyl-3,3-dimethyl-tutan-2-on-and-ol derivatives
PT81988A (en) Process for preparing novel alkylamino-furanone derivatives
HUT42432A (en) Process for preparing substituted phenyl-carbamide derivatives
ZA865376B (en) Process for the preparation of 2-cyanoamino-pyrimidine derivatives
HUT41410A (en) Process for producing 3-khloro-cephalosporin derivatives
YU141582A (en) Process for obtining new benzoyl-phenyl-piperidine derivatives

Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee