HUT38605A - Process for preparinh tetrahydronaphthaline derivatives - Google Patents

Process for preparinh tetrahydronaphthaline derivatives

Info

Publication number
HUT38605A
HUT38605A HU853919A HU391585A HUT38605A HU T38605 A HUT38605 A HU T38605A HU 853919 A HU853919 A HU 853919A HU 391585 A HU391585 A HU 391585A HU T38605 A HUT38605 A HU T38605A
Authority
HU
Hungary
Prior art keywords
formula
compounds
derivatives
preparinh
tetrahydronaphthaline
Prior art date
Application number
HU853919A
Other languages
English (en)
Other versions
HU199773B (en
Inventor
Urs Hengartner
Henri Ramuz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HUT38605A publication Critical patent/HUT38605A/hu
Publication of HU199773B publication Critical patent/HU199773B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/03—Monoamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU853915A 1984-10-11 1985-10-09 Process for production of derivatives of tetrahydronaphtaline and medical compositions containing them HU199773B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH487084 1984-10-11

Publications (2)

Publication Number Publication Date
HUT38605A true HUT38605A (en) 1986-06-30
HU199773B HU199773B (en) 1990-03-28

Family

ID=4283985

Family Applications (1)

Application Number Title Priority Date Filing Date
HU853915A HU199773B (en) 1984-10-11 1985-10-09 Process for production of derivatives of tetrahydronaphtaline and medical compositions containing them

Country Status (21)

Country Link
US (1) US4680310A (hu)
EP (1) EP0177960B1 (hu)
JP (1) JPS6191157A (hu)
KR (1) KR860003200A (hu)
CN (1) CN1007727B (hu)
AT (1) ATE61791T1 (hu)
AU (1) AU589375B2 (hu)
CA (1) CA1287636C (hu)
DE (1) DE3582217D1 (hu)
DK (1) DK464885A (hu)
ES (3) ES8701145A1 (hu)
FI (1) FI83508C (hu)
GR (1) GR852450B (hu)
HU (1) HU199773B (hu)
IL (1) IL76576A0 (hu)
MC (1) MC1706A1 (hu)
NO (1) NO161971C (hu)
NZ (1) NZ213651A (hu)
PH (1) PH23223A (hu)
PT (1) PT81286B (hu)
ZA (1) ZA857681B (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU573828B2 (en) * 1984-05-17 1988-06-23 E.R. Squibb & Sons, Inc. Tetrahydronaphthalenols
DE3630903A1 (de) * 1986-09-11 1988-03-24 Thomae Gmbh Dr K Neue tetrahydronaphthalin- und indanderivate, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
DK171349B1 (da) * 1986-11-14 1996-09-16 Hoffmann La Roche Tetrahydronaphthalenderivater, fremgangsmåde til fremstilling deraf, lægemidler indeholdende forbindelserne samt anvendelse af forbindelserne til fremstilling af lægemidler
PT87163B (pt) * 1987-04-09 1992-07-31 Lilly Co Eli Processo para a preparacao de 1-fenil-3-naftaleniloxi-propanaminas
IT1224405B (it) * 1987-12-23 1990-10-04 Simes Composti attivi sul sistema cardiovascolare
DE3807813A1 (de) * 1988-03-10 1989-09-21 Thomae Gmbh Dr K Neue benzocycloheptenderivate, diese verbindungen enthaltende arzneimittel und verfahren zu deren herstellung
CA2011461A1 (en) * 1989-03-20 1990-09-20 Urs Hengartner Tetrahydronaphthalene derivatives
US5202486A (en) * 1990-07-31 1993-04-13 E. R. Squibb & Sons, Inc. Tetrahydroethanonaphthaleneamine derivatives
US5204373A (en) * 1991-08-26 1993-04-20 Bristol-Myers Squibb Company Farnesylated tetrahydro-naphthalenols as hypolipidemic agents
US5808088A (en) * 1997-04-30 1998-09-15 Roche Colorado Corporation Preparation of mibefradil via an acetamide anion
US5811557A (en) * 1997-04-30 1998-09-22 Roche Colorado Corporation Preparation of mibefradil via an acetonitrile anion
US5811556A (en) * 1997-04-30 1998-09-22 Roche Colorado Corporation Preparation of mibefradil via a naphthalenylacetic acid
WO2010046729A2 (en) * 2008-10-23 2010-04-29 Actelion Pharmaceuticals Ltd Tetrahydronaphthalene compounds
US8575361B2 (en) 2010-03-02 2013-11-05 Concert Pharmaceuticals Inc. Tetrahydronaphthalene derivatives
US8513434B2 (en) 2010-03-02 2013-08-20 Concert Pharmaceuticals Inc. Tetrahydronaphthalene derivatives
EP3585376A4 (en) * 2017-02-15 2020-11-25 Cavion, Inc. CALCIUM CHANNELS INHIBITORS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE913199C (de) * 1952-05-28 1954-06-10 Hartmann & Braun Ag Anzeigeinstrument zur Bestimmung von Polung und ungefaehrer Groesse des Strom- und Spannungsfehlers von Messwandlern in Verbindung mit Messwandler-Pruefeinrichtungen, die nach dem Differentialverfahren arbeiten
US3957845A (en) * 1962-04-27 1976-05-18 Knoll A.G. Chemische Fabriken Trifluoromethyl-substituted phenyl acetonitriles
GB1256753A (hu) * 1969-05-30 1971-12-15
US4127588A (en) * 1976-10-01 1978-11-28 Hoffmann-La Roche Inc. Sulphur containing derivatives
JPS5896045A (ja) * 1981-11-30 1983-06-07 Sumitomo Chem Co Ltd 新規なジフエニルアルカノアミン誘導体およびその製造法

Also Published As

Publication number Publication date
DE3582217D1 (de) 1991-04-25
ZA857681B (en) 1986-05-28
ES8802359A1 (es) 1988-05-16
EP0177960A3 (en) 1988-01-13
FI83508B (fi) 1991-04-15
PT81286B (pt) 1988-02-17
ES554021A0 (es) 1987-12-16
EP0177960A2 (de) 1986-04-16
JPS6191157A (ja) 1986-05-09
NO161971B (no) 1989-07-10
FI853817A0 (fi) 1985-10-02
DK464885A (da) 1986-04-12
MC1706A1 (fr) 1986-09-22
NZ213651A (en) 1989-07-27
US4680310A (en) 1987-07-14
NO161971C (no) 1989-10-18
ES8701145A1 (es) 1986-11-16
PH23223A (en) 1989-06-06
FI853817L (fi) 1986-04-12
CN1007727B (zh) 1990-04-25
NO854036L (no) 1986-04-14
HU199773B (en) 1990-03-28
KR860003200A (ko) 1986-05-21
ES8801174A1 (es) 1987-12-16
EP0177960B1 (de) 1991-03-20
ES547756A0 (es) 1986-11-16
ATE61791T1 (de) 1991-04-15
CN85107496A (zh) 1986-07-23
IL76576A0 (en) 1986-02-28
DK464885D0 (da) 1985-10-10
GR852450B (hu) 1986-02-11
AU4830185A (en) 1986-04-17
PT81286A (en) 1985-11-01
FI83508C (fi) 1991-07-25
CA1287636C (en) 1991-08-13
ES554020A0 (es) 1988-05-16
AU589375B2 (en) 1989-10-12

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HRH9 Withdrawal of annulment decision
HMM4 Cancellation of final prot. due to non-payment of fee