HUS2300036I1 - IL-23 kötõ antitestek - Google Patents

IL-23 kötõ antitestek

Info

Publication number
HUS2300036I1
HUS2300036I1 HUS2300036C HUS2300036C HUS2300036I1 HU S2300036 I1 HUS2300036 I1 HU S2300036I1 HU S2300036 C HUS2300036 C HU S2300036C HU S2300036 C HUS2300036 C HU S2300036C HU S2300036 I1 HUS2300036 I1 HU S2300036I1
Authority
HU
Hungary
Prior art keywords
antibodies
bind
Prior art date
Application number
HUS2300036C
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HUS2300036I1 publication Critical patent/HUS2300036I1/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HUS2300036C 2013-03-08 2023-10-18 IL-23 kötõ antitestek HUS2300036I1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361774732P 2013-03-08 2013-03-08
EP14761062.0A EP2964258B1 (en) 2013-03-08 2014-03-04 Antibodies that bind il-23

Publications (1)

Publication Number Publication Date
HUS2300036I1 true HUS2300036I1 (hu) 2023-11-28

Family

ID=51488096

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE14761062A HUE051357T2 (hu) 2013-03-08 2014-03-04 IL-23 kötõ antitestek
HUS2300036C HUS2300036I1 (hu) 2013-03-08 2023-10-18 IL-23 kötõ antitestek

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE14761062A HUE051357T2 (hu) 2013-03-08 2014-03-04 IL-23 kötõ antitestek

Country Status (40)

Country Link
US (3) US9023358B2 (hu)
EP (3) EP3789037A1 (hu)
JP (1) JP6096938B2 (hu)
KR (2) KR20170103037A (hu)
CN (1) CN105307681B (hu)
AP (1) AP2015008708A0 (hu)
AR (1) AR094877A1 (hu)
AU (1) AU2014226094B2 (hu)
BR (1) BR112015019611B1 (hu)
CA (1) CA2901462C (hu)
CL (1) CL2015002388A1 (hu)
CY (2) CY1123589T1 (hu)
DK (1) DK2964258T3 (hu)
EA (1) EA031524B1 (hu)
EC (1) ECSP15038626A (hu)
ES (1) ES2822662T3 (hu)
FI (1) FIC20230030I1 (hu)
FR (1) FR23C1036I1 (hu)
HK (1) HK1212252A1 (hu)
HR (1) HRP20201633T1 (hu)
HU (2) HUE051357T2 (hu)
IL (2) IL240731B (hu)
JO (1) JOP20140049B1 (hu)
LT (1) LT2964258T (hu)
MA (1) MA38382A1 (hu)
MX (1) MX370396B (hu)
MY (1) MY171226A (hu)
NL (1) NL301247I2 (hu)
PE (1) PE20151529A1 (hu)
PH (1) PH12015501994A1 (hu)
PL (1) PL2964258T3 (hu)
PT (1) PT2964258T (hu)
RS (1) RS60928B1 (hu)
SG (1) SG11201507176VA (hu)
SI (1) SI2964258T1 (hu)
TN (1) TN2015000348A1 (hu)
TW (1) TWI636063B (hu)
UA (1) UA123198C2 (hu)
WO (1) WO2014137962A1 (hu)
ZA (1) ZA201505285B (hu)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR102417A1 (es) * 2014-11-05 2017-03-01 Lilly Co Eli Anticuerpos biespecíficos anti-tnf- / anti-il-23
WO2017074428A1 (en) * 2015-10-30 2017-05-04 Eli Lilly And Company Anti-cgrp/anti-il-23 bispecific antibodies and uses thereof
AR111845A1 (es) 2017-05-03 2019-08-28 Lilly Co Eli Anticuerpos biespecíficos anti-cgrp / anti-il-23 y usos de los mismos
TWI744617B (zh) 2018-03-30 2021-11-01 美商美國禮來大藥廠 治療潰瘍性結腸炎之方法
TWI808397B (zh) 2018-09-11 2023-07-11 美商美國禮來大藥廠 治療牛皮癬之方法
TW202103734A (zh) 2019-04-22 2021-02-01 美商美國禮來大藥廠 治療克隆氏症(crohn's disease)的方法
AU2020368369A1 (en) 2019-10-15 2022-05-12 Eli Lilly And Company Recombinantly engineered, lipase/esterase-deficient mammalian cell lines
CN115135671A (zh) 2019-12-20 2022-09-30 新石生物制药有限公司 抗白介素-23 p19的抗体及其使用方法
CN111718414B (zh) * 2020-06-12 2021-03-02 江苏荃信生物医药有限公司 抗人白介素23单克隆抗体及其应用
WO2022041390A1 (zh) * 2020-08-28 2022-03-03 江苏荃信生物医药股份有限公司 包含高浓度抗人白介素23单克隆抗体的低粘度液体制剂及其制备方法
AR123477A1 (es) 2020-09-10 2022-12-07 Lilly Co Eli Formulaciones de anticuerpos terapéuticos
WO2022251623A1 (en) 2021-05-28 2022-12-01 Eli Lilly And Company Anti-il-23p19 antibody regulation of genes involved in ulcerative colitis
CN113698480B (zh) * 2021-09-18 2022-07-01 东大生物技术(苏州)有限公司 一组il-23单克隆抗体及其医药用途
WO2023056417A1 (en) 2021-09-30 2023-04-06 Eli Lilly And Company Anti-il-23p19 antibody regulation of genes involved in bowel urgency in ulcerative colitis
WO2024077113A1 (en) 2022-10-06 2024-04-11 Eli Lilly And Company Methods of treating fatigue in ulcerative colitis

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060284A (en) 1997-07-25 2000-05-09 Schering Corporation DNA encoding interleukin-B30
US7090847B1 (en) 1999-09-09 2006-08-15 Schering Corporation Mammalian cytokines; related reagents and methods
US7422743B2 (en) 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
NZ567860A (en) 2003-03-10 2009-11-27 Schering Corp Uses of IL-23 agonists and antagonists that specifically bind to IL-23R
US8003108B2 (en) * 2005-05-03 2011-08-23 Amgen Inc. Sclerostin epitopes
SI1896073T1 (sl) 2005-06-30 2013-06-28 Janssen Biotech, Inc. Protitelesa proti il-23, sestavki, prostopki in uporabe
EA013506B1 (ru) * 2005-08-25 2010-06-30 Эли Лилли Энд Компани Антитело к il-23 и его применение
CN101248088A (zh) * 2005-08-25 2008-08-20 伊莱利利公司 抗il-23抗体
EP1931710B1 (en) * 2005-08-31 2017-01-18 Merck Sharp & Dohme Corp. Engineered anti-il-23 antibodies
EA035459B1 (ru) * 2005-12-29 2020-06-19 Сентокор, Инк. Антитело против il-23p19
EP2064242A1 (en) * 2007-02-23 2009-06-03 Schering Corporation Engineered anti-il-23p19 antibodies
PT2059534E (pt) * 2007-02-23 2012-07-17 Schering Corp Anticorpos anti-il-23p19 fabricados por engenharia genética
KR101123487B1 (ko) 2007-03-20 2012-03-23 일라이 릴리 앤드 캄파니 항?스클레로스틴 항체
CL2008001334A1 (es) * 2007-05-08 2008-09-22 Genentech Inc Anticuerpo anti-muc16 disenado con cisteina; conjugado que lo comprende; metodo de produccion; formulacion farmaceutica que lo comprende; y su uso para tratar el cancer.
WO2009082624A2 (en) * 2007-12-10 2009-07-02 Zymogenetics, Inc. Antagonists of il-17a, il-17f, and il-23 and methods of using the same
EP2435480A1 (en) * 2009-05-27 2012-04-04 Ablynx N.V. Biparatopic protein constructs directed against il-23
AP3953A (en) * 2010-11-04 2016-12-22 Boehringer Ingelheim Int Anti-IL-23 antibodies
RU2638806C2 (ru) 2011-05-12 2017-12-15 Дженентек, Инк. Lc-ms/ms способ мониторинга множественных реакций для выявления терапевтических антител в образцах животных с помощью каркасных сигнатурных пептидов

Also Published As

Publication number Publication date
HRP20201633T1 (hr) 2020-12-25
NL301247I2 (nl) 2023-11-01
CN105307681B (zh) 2018-06-26
JOP20140049B1 (ar) 2021-08-17
MX2015011959A (es) 2016-04-07
EP2964258B1 (en) 2020-09-02
PH12015501994A1 (en) 2016-01-11
NZ711147A (en) 2021-03-26
CA2901462C (en) 2017-07-25
EP2964258A4 (en) 2016-10-12
US20140255422A1 (en) 2014-09-11
MA38382A1 (fr) 2017-11-30
US9023358B2 (en) 2015-05-05
KR20150113202A (ko) 2015-10-07
LT2964258T (lt) 2020-10-12
CL2015002388A1 (es) 2016-03-04
CY1123589T1 (el) 2022-03-24
BR112015019611A2 (pt) 2017-08-22
KR20170103037A (ko) 2017-09-12
TWI636063B (zh) 2018-09-21
SI2964258T1 (sl) 2020-10-30
AU2014226094B2 (en) 2016-06-23
ZA201505285B (en) 2017-11-29
EP3789037A1 (en) 2021-03-10
FR23C1036I1 (fr) 2023-12-08
KR101775115B1 (ko) 2017-09-05
US20170275356A1 (en) 2017-09-28
NL301247I1 (nl) 2023-10-11
IL272042B (en) 2021-07-29
AU2014226094A1 (en) 2015-08-27
DK2964258T3 (da) 2020-09-14
CA2901462A1 (en) 2014-09-12
CN105307681A (zh) 2016-02-03
AP2015008708A0 (en) 2015-09-30
IL240731B (en) 2020-01-30
EA201591368A1 (ru) 2015-12-30
JP2016510744A (ja) 2016-04-11
HUE051357T2 (hu) 2021-03-01
SG11201507176VA (en) 2015-10-29
ES2822662T3 (es) 2021-05-04
FIC20230030I1 (fi) 2023-10-03
JP6096938B2 (ja) 2017-03-15
RS60928B1 (sr) 2020-11-30
PE20151529A1 (es) 2015-10-28
PT2964258T (pt) 2020-11-06
EP4311558A2 (en) 2024-01-31
WO2014137962A1 (en) 2014-09-12
AR094877A1 (es) 2015-09-02
HK1212252A1 (en) 2016-06-10
MX370396B (es) 2019-12-11
MY171226A (en) 2019-10-03
US9688753B2 (en) 2017-06-27
CY2023021I1 (el) 2024-02-16
EA031524B1 (ru) 2019-01-31
PL2964258T3 (pl) 2021-02-08
EP4311558A3 (en) 2024-04-10
EP2964258A1 (en) 2016-01-13
US20150232552A1 (en) 2015-08-20
IL240731A0 (en) 2015-10-29
TN2015000348A1 (en) 2017-01-03
IL272042A (en) 2020-02-27
BR112015019611B1 (pt) 2023-05-02
UA123198C2 (uk) 2021-03-03
TW201520225A (zh) 2015-06-01
ECSP15038626A (es) 2015-11-30

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