HUP9902095A3 - New process for the preparation of a growth hormone secretagogue - Google Patents

New process for the preparation of a growth hormone secretagogue

Info

Publication number
HUP9902095A3
HUP9902095A3 HU9902095A HUP9902095A HUP9902095A3 HU P9902095 A3 HUP9902095 A3 HU P9902095A3 HU 9902095 A HU9902095 A HU 9902095A HU P9902095 A HUP9902095 A HU P9902095A HU P9902095 A3 HUP9902095 A3 HU P9902095A3
Authority
HU
Hungary
Prior art keywords
preparation
growth hormone
new process
hormone secretagogue
secretagogue
Prior art date
Application number
HU9902095A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9602949.1A external-priority patent/GB9602949D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of HUP9902095A2 publication Critical patent/HUP9902095A2/hu
Publication of HUP9902095A3 publication Critical patent/HUP9902095A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU9902095A 1995-10-27 1996-10-23 New process for the preparation of a growth hormone secretagogue HUP9902095A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US589895P 1995-10-27 1995-10-27
GBGB9602949.1A GB9602949D0 (en) 1996-02-13 1996-02-13 Process for the preparation of a growth hormone secretagogue

Publications (2)

Publication Number Publication Date
HUP9902095A2 HUP9902095A2 (hu) 1999-10-28
HUP9902095A3 true HUP9902095A3 (en) 2001-05-28

Family

ID=26308687

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9902095A HUP9902095A3 (en) 1995-10-27 1996-10-23 New process for the preparation of a growth hormone secretagogue

Country Status (14)

Country Link
EP (1) EP0863900A1 (hu)
JP (1) JPH11513984A (hu)
KR (1) KR19990067097A (hu)
AR (1) AR004124A1 (hu)
AU (1) AU7468596A (hu)
BR (1) BR9610887A (hu)
CA (1) CA2235511A1 (hu)
CZ (1) CZ128298A3 (hu)
HR (1) HRP960494A2 (hu)
HU (1) HUP9902095A3 (hu)
PL (1) PL326428A1 (hu)
SK (1) SK51198A3 (hu)
WO (1) WO1997015573A1 (hu)
YU (1) YU56596A (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601724D0 (en) * 1996-01-29 1996-03-27 Merck Sharp & Dohme Therapeutic agents
WO1998018815A1 (en) * 1996-10-25 1998-05-07 Merck & Co., Inc. Convergent process for the preparation of a growth hormone secretagogue
US6329342B1 (en) 1997-08-19 2001-12-11 Eli Lilly And Company Treatment of congestive heart failure with growth hormone secretagogues
US6639076B1 (en) 1998-08-18 2003-10-28 Eli Lilly And Company Growth hormone secretagogues
US6828331B1 (en) 1999-02-19 2004-12-07 Eli Lilly And Company Growth hormone secretagogues
EP1159964B1 (en) 2000-05-31 2009-10-28 Pfizer Products Inc. Use of growth hormone secretagogues for stimulating gastrointestinal motility
US7125840B2 (en) 2001-10-09 2006-10-24 Eli Lilly And Company Substituted dipeptides as growth hormone secretagogues
ES2266798T3 (es) 2002-04-09 2007-03-01 Eli Lilly And Company Secretagodos de hormona de crecimiento.
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
CU23558A1 (es) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
MX2009008574A (es) 2007-02-09 2009-12-09 Tranzyme Pharma Inc Moduladores del receptor de grelina macrociclicos y metodos para usar el mismo.
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
US20170121385A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ258412A (en) * 1992-12-11 1997-01-29 Merck & Co Inc Spiro-fused piperidine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
YU56596A (sh) 1999-09-27
CA2235511A1 (en) 1997-05-01
HRP960494A2 (en) 1998-04-30
JPH11513984A (ja) 1999-11-30
PL326428A1 (en) 1998-09-14
EP0863900A1 (en) 1998-09-16
CZ128298A3 (cs) 1998-07-15
SK51198A3 (en) 1998-11-04
AR004124A1 (es) 1998-09-30
AU7468596A (en) 1997-05-15
KR19990067097A (ko) 1999-08-16
BR9610887A (pt) 1999-07-13
WO1997015573A1 (en) 1997-05-01
HUP9902095A2 (hu) 1999-10-28
MX9803316A (es) 1998-09-30

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