PL326428A1 - Method of obtaining a compound stimulating hormonal secretion of a growth hormone - Google Patents

Method of obtaining a compound stimulating hormonal secretion of a growth hormone

Info

Publication number
PL326428A1
PL326428A1 PL96326428A PL32642896A PL326428A1 PL 326428 A1 PL326428 A1 PL 326428A1 PL 96326428 A PL96326428 A PL 96326428A PL 32642896 A PL32642896 A PL 32642896A PL 326428 A1 PL326428 A1 PL 326428A1
Authority
PL
Poland
Prior art keywords
obtaining
growth hormone
hormonal secretion
compound stimulating
stimulating hormonal
Prior art date
Application number
PL96326428A
Other languages
English (en)
Inventor
Peter G Houghton
Ioannis Houpis
Audrey Molina
Joseph E Lynch
Ralph P Volante
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9602949.1A external-priority patent/GB9602949D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PL326428A1 publication Critical patent/PL326428A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL96326428A 1995-10-27 1996-10-23 Method of obtaining a compound stimulating hormonal secretion of a growth hormone PL326428A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US589895P 1995-10-27 1995-10-27
GBGB9602949.1A GB9602949D0 (en) 1996-02-13 1996-02-13 Process for the preparation of a growth hormone secretagogue
PCT/US1996/016954 WO1997015573A1 (en) 1995-10-27 1996-10-23 Process for the preparation of a growth hormone secretagogue

Publications (1)

Publication Number Publication Date
PL326428A1 true PL326428A1 (en) 1998-09-14

Family

ID=26308687

Family Applications (1)

Application Number Title Priority Date Filing Date
PL96326428A PL326428A1 (en) 1995-10-27 1996-10-23 Method of obtaining a compound stimulating hormonal secretion of a growth hormone

Country Status (14)

Country Link
EP (1) EP0863900A1 (hu)
JP (1) JPH11513984A (hu)
KR (1) KR19990067097A (hu)
AR (1) AR004124A1 (hu)
AU (1) AU7468596A (hu)
BR (1) BR9610887A (hu)
CA (1) CA2235511A1 (hu)
CZ (1) CZ128298A3 (hu)
HR (1) HRP960494A2 (hu)
HU (1) HUP9902095A3 (hu)
PL (1) PL326428A1 (hu)
SK (1) SK51198A3 (hu)
WO (1) WO1997015573A1 (hu)
YU (1) YU56596A (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601724D0 (en) * 1996-01-29 1996-03-27 Merck Sharp & Dohme Therapeutic agents
WO1998018815A1 (en) * 1996-10-25 1998-05-07 Merck & Co., Inc. Convergent process for the preparation of a growth hormone secretagogue
US6329342B1 (en) 1997-08-19 2001-12-11 Eli Lilly And Company Treatment of congestive heart failure with growth hormone secretagogues
US6639076B1 (en) 1998-08-18 2003-10-28 Eli Lilly And Company Growth hormone secretagogues
US6828331B1 (en) 1999-02-19 2004-12-07 Eli Lilly And Company Growth hormone secretagogues
ES2333097T3 (es) 2000-05-31 2010-02-17 Raqualia Pharma Inc Uso de secretagogos de la hormona de crecimiento para estimular la motilidad gastrointestinal.
US7125840B2 (en) 2001-10-09 2006-10-24 Eli Lilly And Company Substituted dipeptides as growth hormone secretagogues
WO2003087069A2 (en) 2002-04-09 2003-10-23 Eli Lilly And Company Dipeptidic growth hormone secretagogues
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
CU23558A1 (es) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
KR20090107088A (ko) 2007-02-09 2009-10-12 트랜자임 파르마 인크 거대고리 그렐린 수용체 조절제 및 이의 사용 방법
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
WO2017075535A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL176993B1 (pl) * 1992-12-11 1999-08-31 Merck & Co Inc Nowe związki spiropiperydynowe oraz sposób ich wytwarzania

Also Published As

Publication number Publication date
SK51198A3 (en) 1998-11-04
KR19990067097A (ko) 1999-08-16
CA2235511A1 (en) 1997-05-01
AR004124A1 (es) 1998-09-30
YU56596A (sh) 1999-09-27
EP0863900A1 (en) 1998-09-16
MX9803316A (es) 1998-09-30
JPH11513984A (ja) 1999-11-30
BR9610887A (pt) 1999-07-13
CZ128298A3 (cs) 1998-07-15
HUP9902095A3 (en) 2001-05-28
AU7468596A (en) 1997-05-15
HRP960494A2 (en) 1998-04-30
WO1997015573A1 (en) 1997-05-01
HUP9902095A2 (hu) 1999-10-28

Similar Documents

Publication Publication Date Title
PL327634A1 (en) Growth hormone secretion stimulating compounds
PL338883A1 (en) Growth hormone secretion stimulating compounds
EP0741578A4 (en) HUMAN GROWTH HORMONE
HUP9900870A3 (en) Composition for sustained release of human growth hormone
ZA968989B (en) Polymorphic forms of a growth hormone secretagogue
PL321590A1 (en) Compounds capable to cause liberation of the growth hormone
AU2147192A (en) Method of stimulating immune response using growth hormone
AU1615695A (en) Method for forming bone cement to an implant
PL326428A1 (en) Method of obtaining a compound stimulating hormonal secretion of a growth hormone
EP0785784A4 (en) HETEROCYCLIC PIPERIDINES IN POSITION 4 PROMOTING THE RELEASE OF GROWTH HORMONE
IL116743A0 (en) Pharmaceutical composition comprising a growth hormone
PL356364A1 (en) Application of growth hormone secretion stimulating compound and a set therefor
GB9622440D0 (en) Treatment of congestive heart failure with a growth hormone secretagogue
AU5514586A (en) A process for producing human growth hormone
IL116201A0 (en) Method of preparing confections
GB9602414D0 (en) Camphor compounds promote release of growth hormone
AU1942995A (en) New use of growth hormone
AU4993497A (en) Convergent process for the preparation of a growth hormone secretagogue
PL327511A1 (en) Polymorphous forms of a growth hormone secretion stimulating substance
AU6046294A (en) Process for producing human growth hormone
IL116742A0 (en) Pharmaceutical composition comprising a growth hormone
EP0796095A4 (en) METHOD FOR INHIBITING THE EFFECTS OF GROWTH HORMONE
KR0184754B1 (en) Method for producing human growth hormone
AU5881996A (en) Methods of treatment using growth hormone antagonists
AU1267992A (en) Method of installing a dental implant