HUP9901074A3 - Tetrahydropyrane and tetrahydrothiopyrane aminoacids and pharmaceutical compositions containing them - Google Patents

Tetrahydropyrane and tetrahydrothiopyrane aminoacids and pharmaceutical compositions containing them

Info

Publication number
HUP9901074A3
HUP9901074A3 HU9901074A HUP9901074A HUP9901074A3 HU P9901074 A3 HUP9901074 A3 HU P9901074A3 HU 9901074 A HU9901074 A HU 9901074A HU P9901074 A HUP9901074 A HU P9901074A HU P9901074 A3 HUP9901074 A3 HU P9901074A3
Authority
HU
Hungary
Prior art keywords
tetrahydrothiopyrane
tetrahydropyrane
aminoacids
pharmaceutical compositions
compositions containing
Prior art date
Application number
HU9901074A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of HUP9901074A2 publication Critical patent/HUP9901074A2/hu
Publication of HUP9901074A3 publication Critical patent/HUP9901074A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
HU9901074A 1996-02-07 1997-01-02 Tetrahydropyrane and tetrahydrothiopyrane aminoacids and pharmaceutical compositions containing them HUP9901074A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1127896P 1996-02-07 1996-02-07
PCT/US1997/000255 WO1997029101A1 (en) 1996-02-07 1997-01-02 Novel cyclic amino acids as pharmaceutical agents

Publications (2)

Publication Number Publication Date
HUP9901074A2 HUP9901074A2 (hu) 2001-04-28
HUP9901074A3 true HUP9901074A3 (en) 2001-08-28

Family

ID=21749660

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901074A HUP9901074A3 (en) 1996-02-07 1997-01-02 Tetrahydropyrane and tetrahydrothiopyrane aminoacids and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US5929088A (cg-RX-API-DMAC7.html)
EP (1) EP0888325B1 (cg-RX-API-DMAC7.html)
JP (1) JP2000511877A (cg-RX-API-DMAC7.html)
KR (1) KR19990082349A (cg-RX-API-DMAC7.html)
AT (1) ATE218135T1 (cg-RX-API-DMAC7.html)
AU (1) AU720628B2 (cg-RX-API-DMAC7.html)
BR (1) BR9707366A (cg-RX-API-DMAC7.html)
CA (1) CA2244708A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ296052B6 (cg-RX-API-DMAC7.html)
DE (1) DE69712877T2 (cg-RX-API-DMAC7.html)
DK (1) DK0888325T3 (cg-RX-API-DMAC7.html)
EA (1) EA001534B1 (cg-RX-API-DMAC7.html)
ES (1) ES2176668T3 (cg-RX-API-DMAC7.html)
HU (1) HUP9901074A3 (cg-RX-API-DMAC7.html)
IL (1) IL125562A (cg-RX-API-DMAC7.html)
NO (1) NO983612L (cg-RX-API-DMAC7.html)
NZ (1) NZ326669A (cg-RX-API-DMAC7.html)
PL (1) PL328432A1 (cg-RX-API-DMAC7.html)
PT (1) PT888325E (cg-RX-API-DMAC7.html)
SK (1) SK282665B6 (cg-RX-API-DMAC7.html)
WO (1) WO1997029101A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA97991B (cg-RX-API-DMAC7.html)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL126999A (en) 1996-07-24 2002-03-10 Warner Lambert Co Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain
PT1015415E (pt) 1997-09-18 2003-09-30 Warner Lambert Co Novos processos estereosselectivos para a preparacao de analogos de gabapentina
US6984659B2 (en) 1997-11-18 2006-01-10 Klinikum Der Albert-Ludwigs Universitaet 2-pyrrolidinone derivatives substituted at position 4 for reducing the extracellular glutamate level
DE19751062A1 (de) 1997-11-18 1999-07-08 Univ Ludwigs Albert An 4-Stellung substituierte 2-Pyrrolidinon-Derivate zur Verringerung des extrazellulären Glutamat-Spiegels
TR200001800T2 (tr) * 1997-12-16 2001-03-21 Warner-Lambert Company -4(3)-İkameli -4(3)- aminometil-(tio) piran veya- piperidin türevleri (=Gabapentin analogları), hazırlanmaları ve nörolojik hastalıkların tedavisinde kullanımları
CA2404157A1 (en) * 2000-03-28 2001-10-04 Robert J. Delorenzo Inhibition of a novel calcium injury current that forms in neurons during injury prevents neuronal cell death
WO2002032376A2 (en) 2000-10-06 2002-04-25 Xenoport, Inc. Bile-acid conjugates for providing sustained systemic concentrations of drugs
US6992076B2 (en) 2000-10-06 2006-01-31 Xenoport, Inc. Bile-acid derived compounds for providing sustained systemic concentrations of drugs after oral administration
GB2368579A (en) * 2000-10-31 2002-05-08 Parke Davis & Co Ltd Azole pharmaceutical agents
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
ATE380029T1 (de) 2001-06-11 2007-12-15 Xenoport Inc Prodrugs von gaba-analoga, zusammensetzungen und ihre verwendungszwecke
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
EP1412324A4 (en) 2001-06-11 2004-09-29 Xenoport Inc AMINO ACID CONJUGATES THAT RESULT IN GABA ANALOGA LASTING SYSTEMIC CONCENTRATIONS
AU2002316231A1 (en) 2002-02-19 2003-09-29 Xenoport, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
WO2003080588A1 (en) 2002-03-20 2003-10-02 Xenoport Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof
AU2003243180A1 (en) 2002-05-17 2003-12-12 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US20040092498A1 (en) * 2002-08-16 2004-05-13 David Blakemore Substituted glycine derivatives for use as medicaments
US7060727B2 (en) 2002-12-11 2006-06-13 Xenoport, Inc. Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
PT1572173E (pt) 2002-12-13 2010-05-10 Warner Lambert Co Ligando alfa-2-delta para tratar sintomas do tracto urinário inferior
EP1670451A4 (en) 2003-09-11 2009-10-21 Xenoport Inc TREATMENT AND / OR PREVENTION OF URINARY INCONTINENCE AND PROMOTERS OF GABA ANALOGS
CA2537402C (en) 2003-09-12 2009-05-05 Pfizer Inc. Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors
NZ545989A (en) 2003-09-17 2009-10-30 Xenoport Inc Treating or preventing restless legs syndrome using prodrugs of gaba analogs
ATE516801T1 (de) 2003-10-14 2011-08-15 Xenoport Inc Kristalline form eines gamma-aminobuttersäure- analogons
US20050176680A1 (en) 2003-12-11 2005-08-11 Sepracor, Inc. Combination of sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
CN102429882B (zh) 2004-11-04 2015-03-25 什诺波特有限公司 加巴喷丁前体药物持续释放口服剂型
JP5308350B2 (ja) 2006-12-22 2013-10-09 レコルダーティ アイルランド リミテッド α２δリガンドおよびＮＳＡＩＤを用いた下部尿路機能障害の併用療法
CA2697254A1 (en) * 2007-08-23 2009-02-26 Novartis Ag Aminobenzyl-substituted cyclic sulfones useful as bace inhibitors
US7868043B2 (en) 2008-01-25 2011-01-11 Xenoport, Inc. Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
ES2601852T3 (es) 2008-01-25 2017-02-16 Xenoport, Inc. Forma cristalina de sales de calcio de ácidos (3S)-aminometil-5-metil-hexanoicos y métodos de uso
WO2009094563A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Crystalline form of calcium-salts of (3s)-aminomethyl-b-methyl-hexanoic acids and methods of use
WO2010042759A2 (en) 2008-10-08 2010-04-15 Kyphia Pharmaceuticals Inc Gaba conjugates and methods of use thereof
WO2010084797A1 (ja) * 2009-01-21 2010-07-29 第一三共株式会社 含ヘテロ原子化合物
US9066853B2 (en) 2013-01-15 2015-06-30 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable fiber
CA2903000C (en) 2013-01-28 2021-10-12 Hector L. Lopez Methods of improving tolerability, pharmacodynamics, and efficacy of .beta.-alanine and use therefor
CN114621119A (zh) 2018-05-14 2022-06-14 昌郁医药公司 萘普生和普瑞巴林的1-(酰氧基)-烷基氨基甲酸酯药物缀合物的结晶形式

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US5270317A (en) * 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
EP0641780A1 (en) * 1991-07-09 1995-03-08 Nippon Soda Co., Ltd. Heterocyclic cyclohexanedione derivative, production thereof, and herbicide
US5514801A (en) * 1992-12-29 1996-05-07 Monsanto Company Cyclic sulfone containing retroviral protease inhibitors
GB9314758D0 (en) * 1993-07-16 1993-08-25 Wyeth John & Brother Ltd Heterocyclic derivatives
US5527194A (en) * 1994-02-02 1996-06-18 Brunswick Corporation Thrust sensor for marine drives
US5491152A (en) * 1994-03-23 1996-02-13 The Du Pont Merck Pharmaceutical Company Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis
US5760006A (en) * 1997-06-23 1998-06-02 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating psoriasis

Also Published As

Publication number Publication date
HUP9901074A2 (hu) 2001-04-28
SK106798A3 (en) 1999-07-12
DE69712877T2 (de) 2002-11-14
EA001534B1 (ru) 2001-04-23
CZ245298A3 (cs) 1998-11-11
ATE218135T1 (de) 2002-06-15
PT888325E (pt) 2002-10-31
ZA97991B (en) 1997-08-15
ES2176668T3 (es) 2002-12-01
DK0888325T3 (da) 2002-09-16
PL328432A1 (en) 1999-02-01
JP2000511877A (ja) 2000-09-12
CA2244708A1 (en) 1997-08-14
AU720628B2 (en) 2000-06-08
NO983612L (no) 1998-10-06
DE69712877D1 (de) 2002-07-04
AU1529597A (en) 1997-08-28
EA199800682A1 (ru) 1999-02-25
US5929088A (en) 1999-07-27
EP0888325A1 (en) 1999-01-07
WO1997029101A1 (en) 1997-08-14
SK282665B6 (sk) 2002-11-06
NO983612D0 (no) 1998-08-06
IL125562A (en) 2001-08-08
EP0888325B1 (en) 2002-05-29
KR19990082349A (ko) 1999-11-25
CZ296052B6 (cs) 2005-12-14
NZ326669A (en) 2001-05-25
BR9707366A (pt) 1999-07-20
IL125562A0 (en) 1999-03-12

Similar Documents

Publication Publication Date Title
HUP9901074A3 (en) Tetrahydropyrane and tetrahydrothiopyrane aminoacids and pharmaceutical compositions containing them
GB9616411D0 (en) Shampoo compositions and method
HUP0000733A3 (en) Aminoguanidines and alkoxyguanidines as and pharmaceutical compositions containing them
IL114622A0 (en) Heteroaryl-oxazolidinones and pharmaceutical compositions containing them
ZA9711141B (en) Novel ketobenzamides and their use
IL121236A0 (en) Cycloalkano-pyridines their preparation and pharmaceutical compositions containing them
GB9620390D0 (en) Substances and their uses
HUP9900424A2 (hu) Tiazolil-benzfurán-származékok és a vegyületeket tartalmazó gyógyászati készítmények
GB9625899D0 (en) Substances and their uses
HUP9700446A3 (en) Oilsuspension-concentrate and using thereof
IL120669A0 (en) Benzylamine derivatives and pharmaceutical compositions containing them
PL331423A1 (en) Muporocin and chlorohexidrin containing compositions
IL116015A0 (en) Iminooxymethyleneanilides thdir preparation and compositions containing them
GB9624501D0 (en) Insecticial compositions and method
HUP0000460A3 (en) Imidazopyridazines and pharmaceutical compositions thereof
IL112564A0 (en) 1-beta-methyl-carbapenems and compositions containing them
PL331094A1 (en) Compositions and manufactured goods made using such compositions
PL331523A1 (en) Azolotrizines and azolopyrimidines
IL129607A0 (en) Stabilized pharmaceutical compositions based on quinuprisitine and on dalfopristine and their preparation
GB2318356B (en) Composition and method
PL328334A1 (en) Preparation and application thereof
GB9608505D0 (en) Compositions processes and uses
HUP0000275A3 (en) Phenanethridinium derivatives and pharmaceutical compositions containing them
HUP9901968A3 (en) 2-thioxotetrahydropyrimidin-4-one derivatives and pharmaceutical compositions containing them
IL112094A0 (en) Novel peptides and pharmaceutical compositions comprising them