NO983612D0 - Nye cykliske aminosyrer som farmasöytiske midler - Google Patents

Nye cykliske aminosyrer som farmasöytiske midler

Info

Publication number
NO983612D0
NO983612D0 NO983612A NO983612A NO983612D0 NO 983612 D0 NO983612 D0 NO 983612D0 NO 983612 A NO983612 A NO 983612A NO 983612 A NO983612 A NO 983612A NO 983612 D0 NO983612 D0 NO 983612D0
Authority
NO
Norway
Prior art keywords
pct
amino acids
cyclic amino
pharmaceutical agents
date
Prior art date
Application number
NO983612A
Other languages
English (en)
Other versions
NO983612L (no
Inventor
David C Horwell
Justin S Bryans
Clare O Kneen
Giles S Ratcliffe
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO983612D0 publication Critical patent/NO983612D0/no
Publication of NO983612L publication Critical patent/NO983612L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
NO983612A 1996-02-07 1998-08-06 Nye cykliske aminosyrer som farmas°ytiske midler NO983612L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1127896P 1996-02-07 1996-02-07
PCT/US1997/000255 WO1997029101A1 (en) 1996-02-07 1997-01-02 Novel cyclic amino acids as pharmaceutical agents

Publications (2)

Publication Number Publication Date
NO983612D0 true NO983612D0 (no) 1998-08-06
NO983612L NO983612L (no) 1998-10-06

Family

ID=21749660

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983612A NO983612L (no) 1996-02-07 1998-08-06 Nye cykliske aminosyrer som farmas°ytiske midler

Country Status (22)

Country Link
US (1) US5929088A (no)
EP (1) EP0888325B1 (no)
JP (1) JP2000511877A (no)
KR (1) KR19990082349A (no)
AT (1) ATE218135T1 (no)
AU (1) AU720628B2 (no)
BR (1) BR9707366A (no)
CA (1) CA2244708A1 (no)
CZ (1) CZ296052B6 (no)
DE (1) DE69712877T2 (no)
DK (1) DK0888325T3 (no)
EA (1) EA001534B1 (no)
ES (1) ES2176668T3 (no)
HU (1) HUP9901074A3 (no)
IL (1) IL125562A (no)
NO (1) NO983612L (no)
NZ (1) NZ326669A (no)
PL (1) PL328432A1 (no)
PT (1) PT888325E (no)
SK (1) SK282665B6 (no)
WO (1) WO1997029101A1 (no)
ZA (1) ZA97991B (no)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
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WO1998003167A1 (en) 1996-07-24 1998-01-29 Warner-Lambert Company Isobutylgaba and its derivatives for the treatment of pain
JP3878809B2 (ja) * 1997-09-18 2007-02-07 ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー ガバペンチン類似体を製造するための新規な立体選択的方法
DE19751062A1 (de) * 1997-11-18 1999-07-08 Univ Ludwigs Albert An 4-Stellung substituierte 2-Pyrrolidinon-Derivate zur Verringerung des extrazellulären Glutamat-Spiegels
US6984659B2 (en) 1997-11-18 2006-01-10 Klinikum Der Albert-Ludwigs Universitaet 2-pyrrolidinone derivatives substituted at position 4 for reducing the extracellular glutamate level
KR20010033153A (ko) * 1997-12-16 2001-04-25 로즈 암스트롱, 크리스틴 에이. 트러트웨인 4(3)-치환-4(3)-아미노메틸-(티오)피란 또는 -피페리딘유도체(=가바펜틴 동족체), 그의 제법 및 신경 질환 치료용도
WO2001072311A1 (en) * 2000-03-28 2001-10-04 Delorenzo Robert J Inhibition of a novel calcium injury current that forms in neurons during injury prevents neuronal cell death
WO2002032376A2 (en) 2000-10-06 2002-04-25 Xenoport, Inc. Bile-acid conjugates for providing sustained systemic concentrations of drugs
US6992076B2 (en) 2000-10-06 2006-01-31 Xenoport, Inc. Bile-acid derived compounds for providing sustained systemic concentrations of drugs after oral administration
GB2368579A (en) * 2000-10-31 2002-05-08 Parke Davis & Co Ltd Azole pharmaceutical agents
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
AU2002345638A1 (en) 2001-06-11 2002-12-23 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
HUP0400167A3 (en) 2001-06-11 2012-09-28 Xenoport Inc Prodrugs of gaba analogs, compositions and uses thereof
WO2003077902A1 (en) 2002-02-19 2003-09-25 Xenoport, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
AU2003222033A1 (en) 2002-03-20 2003-10-08 Xenoport Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof
AU2003243180A1 (en) 2002-05-17 2003-12-12 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US20040092498A1 (en) * 2002-08-16 2004-05-13 David Blakemore Substituted glycine derivatives for use as medicaments
US7060727B2 (en) 2002-12-11 2006-06-13 Xenoport, Inc. Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
CA2509605C (en) 2002-12-13 2010-10-05 Warner-Lambert Company Llc Alpha-2-delta ligand to treat lower urinary tract symptoms
MXPA06002731A (es) 2003-09-11 2006-06-05 Xenoport Inc Tratamiento y/o prevencion de incontinencia urinaria utilizando profarmacos de analogos de gaba.
CN1849153A (zh) 2003-09-12 2006-10-18 辉瑞大药厂 含有α－2－δ配体和5－羟色胺/去甲肾上腺素重摄取抑制剂的组合物
MXPA06003043A (es) 2003-09-17 2006-05-31 Xenoport Inc Tratamiento o prevencion del sindrome piernas inquietas utilizando prodrogas de analogos gaba.
NZ546381A (en) 2003-10-14 2010-01-29 Xenoport Inc Crystalline form of gamma-aminobutyric acid analog
PT1691811E (pt) 2003-12-11 2014-10-30 Sunovion Pharmaceuticals Inc Combinação de um sedativo e de um modulador de neurotransmissores e métodos para melhorar a qualidade do sono e tratamento da depressão
US8795725B2 (en) 2004-11-04 2014-08-05 Xenoport, Inc. GABA analog prodrug sustained release oral dosage forms
CA2673545A1 (en) 2006-12-22 2008-07-03 Recordati Ireland Limited Combination therapy of lower urinary tract disorders with .alpha.2.delta. ligands and nsaids
BRPI0815673A2 (pt) * 2007-08-23 2015-02-18 Novartis Ag Sulfonas cíclicas substituídas por aminobenzila úteis como inibidores de bace.
US7872046B2 (en) 2008-01-25 2011-01-18 Xenoport, Inc. Crystalline form of a (3S)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
CA2706575C (en) 2008-01-25 2015-07-14 Xenoport, Inc. Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs
US7868043B2 (en) 2008-01-25 2011-01-11 Xenoport, Inc. Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
BRPI0919811B1 (pt) 2008-10-08 2022-04-19 Xgene Pharmaceutical Inc Conjugados de gaba e métodos de uso dos mesmos
WO2010084797A1 (ja) * 2009-01-21 2010-07-29 第一三共株式会社 含ヘテロ原子化合物
US9066853B2 (en) 2013-01-15 2015-06-30 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable fiber
HUE047629T2 (hu) 2013-01-28 2020-05-28 Lopez Hector L Eljárások ß-alanin tolerancia, farmakodinamika és hatékonyság javítására és azok alkalmazása
EP3793974A4 (en) 2018-05-14 2022-05-04 Xgene Pharmaceutical Inc CRYSTALLINE FORMS OF THE 1-(ACYLOXY)-ALKYL CARBAMATE DRUG CONJUGATE OF NAPROXEN AND PREGABALIN

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US5270317A (en) * 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
BR9206253A (pt) * 1991-07-09 1995-03-14 Nippon Soda Co Derivado de ciclo-hexanodiona heterocíclico, processo para produzir um composto, e, herbicida
US5514801A (en) * 1992-12-29 1996-05-07 Monsanto Company Cyclic sulfone containing retroviral protease inhibitors
GB9314758D0 (en) * 1993-07-16 1993-08-25 Wyeth John & Brother Ltd Heterocyclic derivatives
US5527194A (en) * 1994-02-02 1996-06-18 Brunswick Corporation Thrust sensor for marine drives
US5491152A (en) * 1994-03-23 1996-02-13 The Du Pont Merck Pharmaceutical Company Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis
US5760006A (en) * 1997-06-23 1998-06-02 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating psoriasis

Also Published As

Publication number Publication date
BR9707366A (pt) 1999-07-20
DE69712877D1 (de) 2002-07-04
ES2176668T3 (es) 2002-12-01
IL125562A0 (en) 1999-03-12
JP2000511877A (ja) 2000-09-12
HUP9901074A3 (en) 2001-08-28
CZ245298A3 (cs) 1998-11-11
WO1997029101A1 (en) 1997-08-14
CA2244708A1 (en) 1997-08-14
HUP9901074A2 (hu) 2001-04-28
AU720628B2 (en) 2000-06-08
ATE218135T1 (de) 2002-06-15
PL328432A1 (en) 1999-02-01
EA001534B1 (ru) 2001-04-23
KR19990082349A (ko) 1999-11-25
DK0888325T3 (da) 2002-09-16
IL125562A (en) 2001-08-08
ZA97991B (en) 1997-08-15
NO983612L (no) 1998-10-06
DE69712877T2 (de) 2002-11-14
PT888325E (pt) 2002-10-31
US5929088A (en) 1999-07-27
SK282665B6 (sk) 2002-11-06
NZ326669A (en) 2001-05-25
EP0888325B1 (en) 2002-05-29
EP0888325A1 (en) 1999-01-07
EA199800682A1 (ru) 1999-02-25
SK106798A3 (en) 1999-07-12
AU1529597A (en) 1997-08-28
CZ296052B6 (cs) 2005-12-14

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application