HUP9801838A3 - Indole derivatives as antagonists of excitatory amino acids - Google Patents
Indole derivatives as antagonists of excitatory amino acidsInfo
- Publication number
- HUP9801838A3 HUP9801838A3 HU9801838A HUP9801838A HUP9801838A3 HU P9801838 A3 HUP9801838 A3 HU P9801838A3 HU 9801838 A HU9801838 A HU 9801838A HU P9801838 A HUP9801838 A HU P9801838A HU P9801838 A3 HUP9801838 A3 HU P9801838A3
- Authority
- HU
- Hungary
- Prior art keywords
- antagonists
- amino acids
- indole derivatives
- excitatory amino
- excitatory
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 239000003257 excitatory amino acid Substances 0.000 title 1
- 230000002461 excitatory amino acid Effects 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9504361.8A GB9504361D0 (en) | 1995-03-04 | 1995-03-04 | Heterocyclic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9801838A2 HUP9801838A2 (hu) | 1998-12-28 |
HUP9801838A3 true HUP9801838A3 (en) | 2000-04-28 |
Family
ID=10770638
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9801838A HUP9801838A3 (en) | 1995-03-04 | 1996-03-01 | Indole derivatives as antagonists of excitatory amino acids |
Country Status (23)
Country | Link |
---|---|
US (1) | US5919811A (hu) |
EP (1) | EP0813524A1 (hu) |
JP (1) | JPH11501041A (hu) |
KR (1) | KR19980702735A (hu) |
CN (1) | CN1182417A (hu) |
AR (1) | AR002711A1 (hu) |
AU (1) | AU708291B2 (hu) |
BR (1) | BR9607346A (hu) |
CA (1) | CA2214583A1 (hu) |
CO (1) | CO4700452A1 (hu) |
CZ (1) | CZ277997A3 (hu) |
EA (1) | EA000308B1 (hu) |
GB (1) | GB9504361D0 (hu) |
HU (1) | HUP9801838A3 (hu) |
IL (1) | IL117331A (hu) |
MX (1) | MX9706605A (hu) |
NO (1) | NO309323B1 (hu) |
NZ (1) | NZ303200A (hu) |
PE (1) | PE62396A1 (hu) |
PL (1) | PL322084A1 (hu) |
TW (1) | TW438773B (hu) |
WO (1) | WO1996027588A1 (hu) |
ZA (1) | ZA961697B (hu) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5886191A (en) * | 1997-08-18 | 1999-03-23 | Dupont Pharmaceuticals Company | Amidinoindoles, amidinoazoles, and analogs thereof |
GB9902455D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
JP2005518371A (ja) * | 2001-12-10 | 2005-06-23 | アムジエン・インコーポレーテツド | バニロイド受容体リガンド及び治療に於けるこれらの使用 |
GB0205176D0 (en) * | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
EP1615878B1 (en) * | 2003-01-14 | 2012-04-04 | Cytokinetics, Inc. | Compounds, compositions and methods of treatment for heart failure |
JP5080970B2 (ja) * | 2004-06-17 | 2012-11-21 | サイトキネティクス・インコーポレーテッド | 心疾患を治療するための置換尿素誘導体 |
US7176222B2 (en) | 2004-07-27 | 2007-02-13 | Cytokinetics, Inc. | Syntheses of ureas |
US7538223B2 (en) * | 2005-08-04 | 2009-05-26 | Cytokinetics, Inc. | Compounds, compositions and methods |
WO2007075377A2 (en) * | 2005-12-15 | 2007-07-05 | Cytokinetics, Inc. | Certain chemical entities, compositions and methods |
US20070208000A1 (en) * | 2005-12-15 | 2007-09-06 | Morgan Bradley P | Certain chemical entities, compositions and methods |
EP1959960B1 (en) * | 2005-12-15 | 2013-04-10 | Cytokinetics, Inc. | Certain chemical entities, compositions and methods |
US7825120B2 (en) * | 2005-12-15 | 2010-11-02 | Cytokinetics, Inc. | Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas |
US7718657B2 (en) * | 2005-12-16 | 2010-05-18 | Cytokinetics, Inc. | Certain indanyl urea modulators of the cardiac sarcomere |
JP5178526B2 (ja) * | 2005-12-19 | 2013-04-10 | サイトキネティクス・インコーポレーテッド | 化合物、組成物および方法 |
WO2009035927A2 (en) * | 2007-09-13 | 2009-03-19 | Arete Therapeutics, Inc. | Bis-cyclyl substitued ureas or amides as soluble epoxide hydrolase inhibitors |
PE20091101A1 (es) | 2007-12-18 | 2009-07-26 | Pharminox Ltd | AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO |
JP2012530775A (ja) | 2009-06-23 | 2012-12-06 | ファーミノックス リミテッド | 3−置換−8−置換−3H−イミダゾ[5,1−d][1,2,3,5−テトラジン−4−オン化合物及びその使用 |
US20130012706A1 (en) | 2010-03-01 | 2013-01-10 | Pharminox Limited | Methods and Intermediates for the Synthesis of 4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazines |
WO2012085501A1 (en) | 2010-12-20 | 2012-06-28 | Pharminox Limited | 8 - sulfo - imidazotetrazin- 4 - one compounds and their use as anticancer drug |
TW202128630A (zh) | 2019-11-11 | 2021-08-01 | 荷蘭商卡普三世責任有限公司 | 工業規模上用於生產ε-己內醯胺及硫酸銨之方法及設備 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5145845A (en) * | 1991-05-14 | 1992-09-08 | Warner-Lambert Co. | Substituted 2-carboxylindoles having pharmaceutical activity |
GB9208492D0 (en) * | 1992-04-16 | 1992-06-03 | Glaxo Spa | Heterocyclic compounds |
GB9304500D0 (en) * | 1993-03-05 | 1993-04-21 | Glaxo Spa | Heterocyclic compounds |
US5519048A (en) * | 1993-05-27 | 1996-05-21 | Merrell Pharmaceuticals Inc. | 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof |
-
1995
- 1995-03-04 GB GBGB9504361.8A patent/GB9504361D0/en active Pending
-
1996
- 1996-03-01 EP EP96905833A patent/EP0813524A1/en not_active Withdrawn
- 1996-03-01 AU AU49438/96A patent/AU708291B2/en not_active Ceased
- 1996-03-01 PE PE1996000145A patent/PE62396A1/es not_active Application Discontinuation
- 1996-03-01 KR KR1019970706142A patent/KR19980702735A/ko not_active Application Discontinuation
- 1996-03-01 IL IL11733196A patent/IL117331A/xx not_active IP Right Cessation
- 1996-03-01 CZ CZ972779A patent/CZ277997A3/cs unknown
- 1996-03-01 JP JP8526590A patent/JPH11501041A/ja active Pending
- 1996-03-01 CN CN96193467A patent/CN1182417A/zh active Pending
- 1996-03-01 MX MX9706605A patent/MX9706605A/es unknown
- 1996-03-01 WO PCT/EP1996/000840 patent/WO1996027588A1/en not_active Application Discontinuation
- 1996-03-01 US US08/894,702 patent/US5919811A/en not_active Expired - Fee Related
- 1996-03-01 AR ARP960101610A patent/AR002711A1/es unknown
- 1996-03-01 EA EA199700160A patent/EA000308B1/ru not_active IP Right Cessation
- 1996-03-01 HU HU9801838A patent/HUP9801838A3/hu unknown
- 1996-03-01 CO CO96009937A patent/CO4700452A1/es unknown
- 1996-03-01 BR BR9607346A patent/BR9607346A/pt unknown
- 1996-03-01 ZA ZA9601697A patent/ZA961697B/xx unknown
- 1996-03-01 NZ NZ303200A patent/NZ303200A/xx unknown
- 1996-03-01 PL PL96322084A patent/PL322084A1/xx unknown
- 1996-03-01 CA CA002214583A patent/CA2214583A1/en not_active Abandoned
- 1996-03-19 TW TW085103238A patent/TW438773B/zh active
-
1997
- 1997-09-03 NO NO974043A patent/NO309323B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AR002711A1 (es) | 1998-04-29 |
IL117331A0 (en) | 1996-07-23 |
AU4943896A (en) | 1996-09-23 |
PE62396A1 (es) | 1997-01-11 |
EA000308B1 (ru) | 1999-04-29 |
GB9504361D0 (en) | 1995-04-26 |
EA199700160A1 (ru) | 1998-02-26 |
CN1182417A (zh) | 1998-05-20 |
JPH11501041A (ja) | 1999-01-26 |
CA2214583A1 (en) | 1996-09-12 |
US5919811A (en) | 1999-07-06 |
CO4700452A1 (es) | 1998-12-29 |
AU708291B2 (en) | 1999-07-29 |
BR9607346A (pt) | 1997-12-30 |
EP0813524A1 (en) | 1997-12-29 |
TW438773B (en) | 2001-06-07 |
HUP9801838A2 (hu) | 1998-12-28 |
ZA961697B (en) | 1997-10-01 |
PL322084A1 (en) | 1998-01-05 |
NO974043L (no) | 1997-11-03 |
NZ303200A (en) | 1999-01-28 |
IL117331A (en) | 2000-06-29 |
WO1996027588A1 (en) | 1996-09-12 |
NO974043D0 (no) | 1997-09-03 |
KR19980702735A (ko) | 1998-08-05 |
NO309323B1 (no) | 2001-01-15 |
CZ277997A3 (cs) | 1998-06-17 |
MX9706605A (es) | 1998-02-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU6257594A (en) | Indole derivatives as antagonists of excitatory amino acids | |
HUP9801838A3 (en) | Indole derivatives as antagonists of excitatory amino acids | |
IL133493A0 (en) | Intermediates for the preparation of synthetic excitatory amino acids | |
PL340285A1 (en) | Cyclic amino acids and their derivatives useful as pharmacological agents | |
PL339660A1 (en) | Derivatives of amidocarboxylic acids | |
GB9623908D0 (en) | Amino acid derivatives | |
NO992245D0 (no) | FremgangsmÕte for fremstilling av aminokarboksylsyrer | |
HUP9901630A3 (en) | Indole-2,3-dione-3-oxime derivatives as antagonists of excitatory amino acids, preparation and use thereof | |
SI0964856T1 (en) | Bicyclic amino acids | |
PL326081A1 (en) | Novel derivatives of amino acids, their production and application | |
GB9605429D0 (en) | Excitatory amino acid receptor antagonists | |
NZ323205A (en) | Excitatory amino acid derivatives | |
AU3278195A (en) | Excitatory amino acid receptor antagonists | |
AU7731096A (en) | Excitatory amino acid receptor antagonists | |
HUP9900089A3 (en) | Peptide derivatives of dolastatin 15 | |
NO963000D0 (no) | Bedret fordöyelighet av farmasöytisk virksomme -aminosyrer | |
HUP0001661A3 (en) | Quinoline-2-carboxylic acid derivative and its use as excitatory amino acids antagonist | |
AU7657794A (en) | Indole derivatives as antagonists of excitatory amino acids | |
PL317853A1 (en) | Derivatives of amino acids | |
GR3033713T3 (en) | N-sulphonyl and n-sulphinyl amino acid derivatives as microbicides | |
IL118781A0 (en) | Preparation of N-protected 4-ketoproline derivatives | |
PL326699A1 (en) | Method of obtaining derivatives of 3-phenyl-1-methylenedioxyphenyl-indane 2-carboxylic acids | |
GB9605434D0 (en) | Excitatory amino acid derivatives | |
ZA965344B (en) | New amino acid derivatives | |
ZA955497B (en) | Peptide derivatives of alpha-MSH-and their application |