HUP9801094A3 - Process for producing azithromycin - Google Patents

Process for producing azithromycin

Info

Publication number
HUP9801094A3
HUP9801094A3 HU9801094A HUP9801094A HUP9801094A3 HU P9801094 A3 HUP9801094 A3 HU P9801094A3 HU 9801094 A HU9801094 A HU 9801094A HU P9801094 A HUP9801094 A HU P9801094A HU P9801094 A3 HUP9801094 A3 HU P9801094A3
Authority
HU
Hungary
Prior art keywords
azithromycin
producing
producing azithromycin
Prior art date
Application number
HU9801094A
Other languages
English (en)
Original Assignee
Hovione Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hovione Int Ltd filed Critical Hovione Int Ltd
Publication of HU9801094D0 publication Critical patent/HU9801094D0/hu
Publication of HUP9801094A2 publication Critical patent/HUP9801094A2/hu
Publication of HUP9801094A3 publication Critical patent/HUP9801094A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Catalysts (AREA)
HU9801094A 1997-05-19 1998-05-15 Process for producing azithromycin HUP9801094A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT102006A PT102006B (pt) 1997-05-19 1997-05-19 Novo processo de preparacao de azitromicina

Publications (3)

Publication Number Publication Date
HU9801094D0 HU9801094D0 (en) 1998-07-28
HUP9801094A2 HUP9801094A2 (hu) 1998-12-28
HUP9801094A3 true HUP9801094A3 (en) 2000-03-28

Family

ID=20085680

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801094A HUP9801094A3 (en) 1997-05-19 1998-05-15 Process for producing azithromycin

Country Status (14)

Country Link
US (1) US6013778A (hu)
EP (1) EP0879823B1 (hu)
JP (1) JP3899181B2 (hu)
CN (1) CN1125076C (hu)
AT (1) ATE231516T1 (hu)
AU (1) AU722688B2 (hu)
CA (1) CA2237747C (hu)
DE (1) DE69810842T2 (hu)
ES (1) ES2191256T3 (hu)
HU (1) HUP9801094A3 (hu)
IL (1) IL124397A (hu)
IN (1) IN189736B (hu)
NZ (1) NZ330228A (hu)
PT (1) PT102006B (hu)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861411B1 (en) 1997-12-02 2005-03-01 Pfizer, Inc. Method of treating eye infections with azithromycin
TW546302B (en) * 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
FR2791680B1 (fr) * 1999-03-29 2001-06-29 Merial Sas Procede utile pour reduire les intermediaires imidates issus d'un rearrangement de beckmann d'un macrocycle 8a-azalide
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US6239113B1 (en) 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
FR2806724B1 (fr) * 2000-03-24 2003-12-05 Merial Sas Procede pour la preparation de derives 9-deoxo-8a-aza- (8a-alkyl)-8a-homoerythromycine a a partir de la 9-deoxo-9 (z)-hydroxyiminoerythromycine a
US6528492B1 (en) 2000-07-25 2003-03-04 Instituto De Investigacion En Quimica Aplicada S.C. Single-step process for preparing 7, 16-deoxy-2-aza-10-0-cladinosil-12-0-desosaminil-4, 5-dihydroxy-6-ethyl-3,5,9,11,13,15-hexamethylbicycle (11.2.1) hexadeca-1(2)-en-ona and obtaining a new form of 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin a
ATE306491T1 (de) * 2000-08-23 2005-10-15 Wockhardt Ltd Verfahren zur herstellung von wasserfreiem azithromycin
CN100341886C (zh) * 2000-11-27 2007-10-10 桑多斯股份公司 大环内酯类化合物的溶剂化物
CZ303343B6 (cs) 2000-11-27 2012-08-08 Sandoz Ag Zpusob prípravy azithromycinu ve forme monohydrátu
ES2179756B1 (es) * 2000-11-30 2004-10-01 Ercros Industrial, S.A. Procedimiento de obtencion de azaeritromicina.
KR100491183B1 (ko) 2001-03-21 2005-05-25 한미약품 주식회사 아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물
ITMI20021209A1 (it) * 2002-06-04 2003-12-04 Chemi Spa Processo di preparazione di azitromicina ad elevata purezza
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7683162B2 (en) * 2004-08-30 2010-03-23 Taro Pharmaceutical Industries Limited Process of preparing a crystalline azithromycin monohydrate
CN1304407C (zh) * 2004-09-03 2007-03-14 南京圣和药业有限公司 一种阿奇霉素的精制方法
ES2407033T3 (es) 2007-05-04 2013-06-11 Mallinckrodt Llc Procedimientos mejorados para la preparación de opiáceos 6-alfa-hidroxi-n-alquilados
EP2167505B1 (en) 2007-07-17 2012-11-28 Mallinckrodt LLC Preparation of n-alkylated opiates by reductive amination
NZ607842A (en) 2008-09-30 2013-12-20 Mallinckrodt Llc Processes for the selective amination of ketomorphinans
JP5685543B2 (ja) * 2008-10-24 2015-03-18 メリアル リミテッド マクロライド系化合物の合成方法
US8946419B2 (en) 2009-02-23 2015-02-03 Mallinckrodt Llc (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives
CA2764884C (en) 2009-06-11 2017-04-04 Mallinckrodt Llc Reductive amination of 6-keto normorphinans by catalytic hydrogen transfer
CN102803267A (zh) 2009-06-11 2012-11-28 马林克罗特有限公司 通过催化氢转移的6-α-氨基N-取代的吗啡喃的制备
PL2718294T3 (pl) 2011-06-09 2019-04-30 SpecGx LLC Redukcyjne aminowanie 6-keto morfinanów przez katalityczne przeniesienie wodoru
KR20140063763A (ko) 2011-09-08 2014-05-27 말린크로트 엘엘씨 중간체를 단리하지 않는 알칼로이드의 제조 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
PH19293A (en) * 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof
DK0699207T3 (da) * 1993-05-19 1997-12-08 Pfizer Mellemprodukt til azithromycin

Also Published As

Publication number Publication date
DE69810842D1 (de) 2003-02-27
AU722688B2 (en) 2000-08-10
CN1125076C (zh) 2003-10-22
EP0879823B1 (en) 2003-01-22
CA2237747C (en) 2007-04-10
HU9801094D0 (en) 1998-07-28
DE69810842T2 (de) 2003-11-20
CN1199736A (zh) 1998-11-25
ATE231516T1 (de) 2003-02-15
IL124397A0 (en) 1998-12-06
PT102006A (pt) 1998-12-31
IN189736B (hu) 2003-04-19
ES2191256T3 (es) 2003-09-01
EP0879823A1 (en) 1998-11-25
PT102006B (pt) 2000-06-30
NZ330228A (en) 1999-06-29
JPH10316699A (ja) 1998-12-02
HUP9801094A2 (hu) 1998-12-28
JP3899181B2 (ja) 2007-03-28
US6013778A (en) 2000-01-11
IL124397A (en) 2003-09-17
CA2237747A1 (en) 1998-11-19
AU6193898A (en) 1998-11-19

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees
NF4A Restoration of patent protection
FD9A Lapse of provisional protection due to non-payment of fees