FR2791680B1 - Procede utile pour reduire les intermediaires imidates issus d'un rearrangement de beckmann d'un macrocycle 8a-azalide - Google Patents

Procede utile pour reduire les intermediaires imidates issus d'un rearrangement de beckmann d'un macrocycle 8a-azalide

Info

Publication number
FR2791680B1
FR2791680B1 FR9903885A FR9903885A FR2791680B1 FR 2791680 B1 FR2791680 B1 FR 2791680B1 FR 9903885 A FR9903885 A FR 9903885A FR 9903885 A FR9903885 A FR 9903885A FR 2791680 B1 FR2791680 B1 FR 2791680B1
Authority
FR
France
Prior art keywords
reducing
useful method
beckmann rearrangement
azalide
macrocycle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9903885A
Other languages
English (en)
Other versions
FR2791680A1 (fr
Inventor
Patrick Leon
Frederic Lhermitte
Denis Largeau
Ronan Guevel
Denis Pauze
Gilles Oddon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Animal Health France SAS
Original Assignee
Merial SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial SAS filed Critical Merial SAS
Priority to FR9903885A priority Critical patent/FR2791680B1/fr
Priority to PCT/FR2000/000753 priority patent/WO2000058327A1/fr
Priority to EP00912740A priority patent/EP1165583A1/fr
Priority to CA002361043A priority patent/CA2361043A1/fr
Priority to AU34394/00A priority patent/AU3439400A/en
Publication of FR2791680A1 publication Critical patent/FR2791680A1/fr
Application granted granted Critical
Publication of FR2791680B1 publication Critical patent/FR2791680B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
FR9903885A 1999-03-29 1999-03-29 Procede utile pour reduire les intermediaires imidates issus d'un rearrangement de beckmann d'un macrocycle 8a-azalide Expired - Fee Related FR2791680B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR9903885A FR2791680B1 (fr) 1999-03-29 1999-03-29 Procede utile pour reduire les intermediaires imidates issus d'un rearrangement de beckmann d'un macrocycle 8a-azalide
PCT/FR2000/000753 WO2000058327A1 (fr) 1999-03-29 2000-03-24 Procede pour reduire imidates pour produire un macrocycle 8a-azalide
EP00912740A EP1165583A1 (fr) 1999-03-29 2000-03-24 Procede pour reduire imidates pour produire un macrocycle 8a-azalide
CA002361043A CA2361043A1 (fr) 1999-03-29 2000-03-24 Procede pour reduire imidates pour produire un macrocycle 8a-azalide
AU34394/00A AU3439400A (en) 1999-03-29 2000-03-24 Method for reducing imidates to produce an 8a-azalide macrocycle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9903885A FR2791680B1 (fr) 1999-03-29 1999-03-29 Procede utile pour reduire les intermediaires imidates issus d'un rearrangement de beckmann d'un macrocycle 8a-azalide

Publications (2)

Publication Number Publication Date
FR2791680A1 FR2791680A1 (fr) 2000-10-06
FR2791680B1 true FR2791680B1 (fr) 2001-06-29

Family

ID=9543746

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9903885A Expired - Fee Related FR2791680B1 (fr) 1999-03-29 1999-03-29 Procede utile pour reduire les intermediaires imidates issus d'un rearrangement de beckmann d'un macrocycle 8a-azalide

Country Status (5)

Country Link
EP (1) EP1165583A1 (fr)
AU (1) AU3439400A (fr)
CA (1) CA2361043A1 (fr)
FR (1) FR2791680B1 (fr)
WO (1) WO2000058327A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482931B2 (en) 2000-03-24 2002-11-19 Merial Process for the preparation of 9-deoxo-8a-aza-(8a-alkyl)-8a-homoerythromycin A derivatives from 9-deoxo-9 (Z)-hydroxyiminoerythromycin A
FR2806724B1 (fr) * 2000-03-24 2003-12-05 Merial Sas Procede pour la preparation de derives 9-deoxo-8a-aza- (8a-alkyl)-8a-homoerythromycine a a partir de la 9-deoxo-9 (z)-hydroxyiminoerythromycine a

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1100504A (en) * 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
CA2064634C (fr) * 1991-04-04 1998-08-04 James V. Heck Derives de 9-desoxo-8a-aza-8a-homoerythromycine a modifies en positions 4"- et 8a
PT102006B (pt) * 1997-05-19 2000-06-30 Hovione Sociedade Quimica S A Novo processo de preparacao de azitromicina

Also Published As

Publication number Publication date
FR2791680A1 (fr) 2000-10-06
WO2000058327A1 (fr) 2000-10-05
AU3439400A (en) 2000-10-16
EP1165583A1 (fr) 2002-01-02
CA2361043A1 (fr) 2000-10-05

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Legal Events

Date Code Title Description
ST Notification of lapse