HUP9800369A1 - Pelletalapú, nagy hatóanyag-tartalmú, ellenőrzött felszabadulású, kálium-klorid-tartalmú gyógyszerkészítmény és eljárás ennek előállítására - Google Patents

Pelletalapú, nagy hatóanyag-tartalmú, ellenőrzött felszabadulású, kálium-klorid-tartalmú gyógyszerkészítmény és eljárás ennek előállítására

Info

Publication number
HUP9800369A1
HUP9800369A1 HU9800369A HUP9800369A HUP9800369A1 HU P9800369 A1 HUP9800369 A1 HU P9800369A1 HU 9800369 A HU9800369 A HU 9800369A HU P9800369 A HUP9800369 A HU P9800369A HU P9800369 A1 HUP9800369 A1 HU P9800369A1
Authority
HU
Hungary
Prior art keywords
weight
potassium
pellet
controlled release
potassium chloride
Prior art date
Application number
HU9800369A
Other languages
English (en)
Inventor
Tibor Nagy
Károly Pataki
Gábor Günther
Pál Fekete
Gábor Faragó
Blanka Lady
Original Assignee
EGIS Gyógyszergyár Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EGIS Gyógyszergyár Rt. filed Critical EGIS Gyógyszergyár Rt.
Priority to HU9800369A priority Critical patent/HU221435B/hu
Publication of HU9800369D0 publication Critical patent/HU9800369D0/hu
Priority to PCT/HU1999/000013 priority patent/WO1999042087A2/en
Priority to CZ20002858A priority patent/CZ299182B6/cs
Priority to PL343268A priority patent/PL193028B1/pl
Priority to AU25404/99A priority patent/AU2540499A/en
Priority to SK1188-2000A priority patent/SK287281B6/sk
Publication of HUP9800369A1 publication Critical patent/HUP9800369A1/hu
Publication of HU221435B publication Critical patent/HU221435B/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

Atalálmány adagőlási egységeként 500-1000 mg káliűm-klőridőttartalmazó, legalább 70tömeg% káliűm-klőrid-tartalmú, szabályőzőtthatóanyag-felszabadűlású műltidózisú, pelletalapú tablettára vagykeményzselatin kapszűlára vőnatkőzik. A találmány szerinti tablettavagy keményzselatin kapszűla előnyösen legalább 70tömeg% káliűm-klőridőt, 10-25tömeg% mikrőkristályős cellűlózt, 0,1-0,5tömeg%összetapadást gátló anyagőt és 0,1-5,0tömeg% hidrőfőbizálószerttartalmazó, közel gömb alakú szemcséket (pelleteket); e szemcsékrefelvitt, 3-10tömeg% etil-akrilát-metil-metakrilát kőpőlimert és/vagyammóniűm-metakrilát kőpőlimert, hidrőfőbizálószert, talkűmőt és kívántesetben színezéket tartalmazó bevőnatőt; kívánt esetben a bevőnatrafelvitt, fenti összetételű bevőnatlan káliűm-klőrid-szemcséket éstővábbi segédanyagőkat tartalmaz. ŕ
HU9800369A 1998-02-20 1998-02-20 Pellet-based pharmaceutical composition of controlled release with high content of potassium-chloride, and process for it's production HU221435B (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
HU9800369A HU221435B (en) 1998-02-20 1998-02-20 Pellet-based pharmaceutical composition of controlled release with high content of potassium-chloride, and process for it's production
PCT/HU1999/000013 WO1999042087A2 (en) 1998-02-20 1999-02-19 Controlled release potassium chloride pellet based pharmaceutical compositions having a high active ingredient content
CZ20002858A CZ299182B6 (cs) 1998-02-20 1999-02-19 Vícedávková farmaceutická kompozice v tuhé perorální forme s rízeným uvolnováním, výhodne ve forme tablet nebo tvrdých želatinových kapslí s obsahem chloridu draselného
PL343268A PL193028B1 (pl) 1998-02-20 1999-02-19 Kompozycje farmaceutyczne o kontrolowanym uwalnianiu chlorku potasu oparte na granulkach o wysokiej zawartości składnika aktywnego oraz sposób ich wytwarzania
AU25404/99A AU2540499A (en) 1998-02-20 1999-02-19 Controlled release potassium chloride pellet based pharmaceutical compositions having a high active ingredient content
SK1188-2000A SK287281B6 (sk) 1998-02-20 1999-02-19 Viacdávková farmaceutická kompozícia v tuhej perorálnej forme s riadeným uvoľňovaním a spôsob jej prípravy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9800369A HU221435B (en) 1998-02-20 1998-02-20 Pellet-based pharmaceutical composition of controlled release with high content of potassium-chloride, and process for it's production

Publications (3)

Publication Number Publication Date
HU9800369D0 HU9800369D0 (en) 1998-04-28
HUP9800369A1 true HUP9800369A1 (hu) 2000-08-28
HU221435B HU221435B (en) 2002-10-28

Family

ID=89996172

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800369A HU221435B (en) 1998-02-20 1998-02-20 Pellet-based pharmaceutical composition of controlled release with high content of potassium-chloride, and process for it's production

Country Status (6)

Country Link
AU (1) AU2540499A (hu)
CZ (1) CZ299182B6 (hu)
HU (1) HU221435B (hu)
PL (1) PL193028B1 (hu)
SK (1) SK287281B6 (hu)
WO (1) WO1999042087A2 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19928312A1 (de) * 1999-06-16 2000-12-21 Schering Ag Arzneimittelzubereitung mit verzögerter Wirkstoffabgabe
DE10347242A1 (de) * 2003-10-10 2005-05-04 Wella Ag Farbstoffhaltige Pellets zum Färben von Keratinfasern
WO2007135470A1 (en) * 2006-05-19 2007-11-29 EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársaság Process for the preparation and surface coating of pellets
DE102008063800A1 (de) 2008-12-19 2010-06-24 Henkel Ag & Co. Kgaa Beschichtete Färbemittel
CN102961363B (zh) * 2012-12-14 2014-09-17 河南中帅医药科技股份有限公司 氯化钾缓释胶囊
EP3213747B1 (en) 2016-03-04 2019-02-13 Laboratorio Reig Jofre S.A. Tablets with a high-content of active ingredients useful for treating hair loss or stimulating its growth
EP4308286A1 (de) 2021-03-16 2024-01-24 Symrise AG Wirkstoffkapseln

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
CH658188A5 (de) * 1984-03-23 1986-10-31 Ciba Geigy Ag Lagerstabile schnellzerfallende pharmazeutische presslinge.
US5397574A (en) * 1993-10-04 1995-03-14 Andrx Pharmaceuticals, Inc. Controlled release potassium dosage form

Also Published As

Publication number Publication date
WO1999042087A3 (en) 1999-11-25
HU9800369D0 (en) 1998-04-28
SK287281B6 (sk) 2010-05-07
WO1999042087A2 (en) 1999-08-26
SK11882000A3 (sk) 2001-01-18
CZ20002858A3 (cs) 2001-01-17
PL343268A1 (en) 2001-08-13
HU221435B (en) 2002-10-28
PL193028B1 (pl) 2007-01-31
CZ299182B6 (cs) 2008-05-14
AU2540499A (en) 1999-09-06

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Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: EGIS GYOGYSZERGYAR NYRT., HU

Free format text: FORMER OWNER(S): EGIS GYOGYSZERGYAR RT., HU