HUP9601241A3 - Stabile liquide composition containing urate oxydase, and lyophilised product for its preparation - Google Patents

Stabile liquide composition containing urate oxydase, and lyophilised product for its preparation

Info

Publication number
HUP9601241A3
HUP9601241A3 HU9601241A HUP9601241A HUP9601241A3 HU P9601241 A3 HUP9601241 A3 HU P9601241A3 HU 9601241 A HU9601241 A HU 9601241A HU P9601241 A HUP9601241 A HU P9601241A HU P9601241 A3 HUP9601241 A3 HU P9601241A3
Authority
HU
Hungary
Prior art keywords
stabile
preparation
composition containing
lyophilised product
liquide
Prior art date
Application number
HU9601241A
Other languages
English (en)
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of HU9601241D0 publication Critical patent/HU9601241D0/hu
Publication of HUP9601241A2 publication Critical patent/HUP9601241A2/hu
Publication of HUP9601241A3 publication Critical patent/HUP9601241A3/hu
Publication of HU225147B1 publication Critical patent/HU225147B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/443—Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
HU9601241A 1995-05-11 1996-05-09 Stabile liquide composition containing urate oxydase, and lyophilised product for its preparation HU225147B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9505606A FR2733914B1 (fr) 1995-05-11 1995-05-11 Composition de liquide stable contenant de l'urate oxydase et composition lyophilisee pour sa preparation
US08/644,163 US5811096A (en) 1995-05-11 1996-05-10 Stable liquid composition containing urate oxidase and lyophilized composition for its preparation

Publications (4)

Publication Number Publication Date
HU9601241D0 HU9601241D0 (en) 1996-07-29
HUP9601241A2 HUP9601241A2 (en) 1997-04-28
HUP9601241A3 true HUP9601241A3 (en) 2000-06-28
HU225147B1 HU225147B1 (en) 2006-07-28

Family

ID=26231954

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9601241A HU225147B1 (en) 1995-05-11 1996-05-09 Stabile liquide composition containing urate oxydase, and lyophilised product for its preparation

Country Status (24)

Country Link
US (1) US5811096A (hu)
EP (1) EP0742013B1 (hu)
JP (1) JP2950775B2 (hu)
CN (1) CN1090972C (hu)
AT (1) ATE183925T1 (hu)
AU (1) AU710288B2 (hu)
BR (1) BR1100337A (hu)
CA (1) CA2175971C (hu)
CZ (1) CZ290799B6 (hu)
DE (1) DE69604009T2 (hu)
DK (1) DK0742013T3 (hu)
EA (1) EA000024B1 (hu)
ES (1) ES2137635T3 (hu)
FR (1) FR2733914B1 (hu)
GR (1) GR3031896T3 (hu)
HU (1) HU225147B1 (hu)
IL (1) IL118171A (hu)
NO (1) NO315261B1 (hu)
NZ (1) NZ286554A (hu)
PL (1) PL184135B1 (hu)
SG (1) SG42355A1 (hu)
SI (1) SI0742013T1 (hu)
TW (1) TW420614B (hu)
ZA (1) ZA963683B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030166525A1 (en) * 1998-07-23 2003-09-04 Hoffmann James Arthur FSH Formulation
US6783965B1 (en) 2000-02-10 2004-08-31 Mountain View Pharmaceuticals, Inc. Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
ES2404074T3 (es) * 1998-08-06 2013-05-23 Mountain View Pharmaceuticals, Inc. Conjugados de peg-oxidasa de urato y su uso
FR2782455B3 (fr) * 1998-08-20 2000-09-15 Sanofi Sa Composition pharmaceutique injectable a base d'un sel pharmaceutiquement acceptable du clopidogrel ou de ticlopidine
EP1598074B1 (en) * 2003-02-28 2019-01-02 Chugai Seiyaku Kabushiki Kaisha Stabilized protein-containing formulations
MXPA05010635A (es) * 2003-04-02 2005-12-12 Ares Trading Sa Formulaciones farmaceuticas liquidas de hormona estimulante de foliculos y hormona luteinizante junto con un surfactante no ionico.
EP1638595B1 (en) * 2003-06-20 2013-03-20 Ares Trading S.A. Freeze-dried fsh / lh formulations
ES2538357T3 (es) 2005-04-11 2015-06-19 Crealta Pharmaceuticals Llc Formas variantes de urato oxidasa y uso de las mismas
PL215157B1 (pl) 2005-04-11 2013-10-31 Savient Pharmaceuticals Wyizolowana urykaza, zawierajaca ja kompozycja farmaceutyczna, kodujacy ja wyizolowany kwas nukleinowy, zawierajacy go wektor i obejmujaca ten wektor komórka gospodarza oraz sposoby wytwarzania urykazy oraz zawierajacej urykaze kompozycji farmaceutycznej
WO2008051178A2 (en) 2006-04-12 2008-05-02 Savient Pharmaceuticals, Inc. Purification of proteins with cationic surfactant
US8148123B2 (en) * 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
CN1864744B (zh) * 2005-05-18 2010-09-29 杭州北斗生物技术有限公司 含有尿酸氧化酶的药用制剂
US20090081122A1 (en) * 2005-05-23 2009-03-26 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
CZ2011827A3 (cs) 2009-06-25 2012-09-26 Savient Pharmaceuticals, Inc. Zpusoby a sady pro predpovídání rizika reakce na infuzi a ztráty odezvy zpusobené protilátkami, monitorováním kyseliny mocové v séru behem lécby pegylovanou urikázou
CN105412942B (zh) * 2015-12-23 2019-02-26 沈阳三生制药有限责任公司 聚乙二醇化的重组产朊假丝酵母尿酸氧化酶冻干注射剂
US20190060241A1 (en) * 2016-04-13 2019-02-28 Medimmune, Llc Use of amino acids as stabilizing compounds in pharmaceutical compositions containing high concentrations of protein-based therapeutic agents
KR101744900B1 (ko) 2017-01-20 2017-06-08 주식회사 대웅 보툴리눔 독소를 포함하는 안정한 액상 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997470A (en) * 1971-10-20 1976-12-14 Mallinckrodt, Inc. Surfactant containing reagent formulations for assaying biological specimens and methods of preparing same
US3928137A (en) * 1971-10-20 1975-12-23 Mallinckrodt Inc Reagent formulation for uric acid assay
JPS51104807A (en) * 1975-03-12 1976-09-17 Hitachi Ltd Teepurekoodano ootoribaasuseigyokairo
JPS5417027A (en) * 1977-07-07 1979-02-08 Canon Inc Image forming system
DE3126759A1 (de) * 1981-07-07 1983-01-27 Boehringer Mannheim Gmbh, 6800 Mannheim Loesliche leber-uricase, verfahren zu ihrer herstellung und verwendung
JPS60224499A (ja) * 1984-04-23 1985-11-08 Toyobo Co Ltd 安定なウリカ−ゼ製剤
DE3743405A1 (de) * 1987-05-14 1988-11-24 Boehringer Mannheim Gmbh Verfahren zur bestimmung von fructosamin
JPH0243471A (ja) * 1988-08-03 1990-02-14 Iwataro Moriyama 立体駐車装置

Also Published As

Publication number Publication date
IL118171A0 (en) 1996-09-12
CN1147961A (zh) 1997-04-23
ZA963683B (en) 1997-11-10
PL314147A1 (en) 1996-11-12
JP2950775B2 (ja) 1999-09-20
HU225147B1 (en) 2006-07-28
PL184135B1 (pl) 2002-09-30
ATE183925T1 (de) 1999-09-15
AU5213996A (en) 1996-11-21
CZ290799B6 (cs) 2002-10-16
CA2175971C (en) 2003-12-30
DK0742013T3 (da) 2000-03-06
DE69604009T2 (de) 2000-04-06
DE69604009D1 (de) 1999-10-07
EP0742013B1 (fr) 1999-09-01
GR3031896T3 (en) 2000-02-29
BR1100337A (pt) 2000-07-25
JPH0925242A (ja) 1997-01-28
CZ135096A3 (en) 1996-12-11
EP0742013A1 (fr) 1996-11-13
ES2137635T3 (es) 1999-12-16
NZ286554A (en) 1998-09-24
CA2175971A1 (en) 1996-11-12
US5811096A (en) 1998-09-22
SG42355A1 (en) 1997-08-15
TW420614B (en) 2001-02-01
EA199600024A2 (ru) 1996-12-30
NO961915L (no) 1996-11-12
MX9601756A (es) 1997-07-31
NO961915D0 (no) 1996-05-10
EA199600024A3 (ru) 1997-03-31
FR2733914B1 (fr) 1997-08-01
SI0742013T1 (en) 1999-12-31
AU710288B2 (en) 1999-09-16
EA000024B1 (ru) 1997-12-30
HUP9601241A2 (en) 1997-04-28
HU9601241D0 (en) 1996-07-29
IL118171A (en) 2000-08-31
CN1090972C (zh) 2002-09-18
NO315261B1 (no) 2003-08-11
FR2733914A1 (fr) 1996-11-15

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