MX9601756A - Composicion liquida estable que contiene urato-oxidasa, y composicion liofilizada para su preparacion. - Google Patents

Composicion liquida estable que contiene urato-oxidasa, y composicion liofilizada para su preparacion.

Info

Publication number
MX9601756A
MX9601756A MX9601756A MX9601756A MX9601756A MX 9601756 A MX9601756 A MX 9601756A MX 9601756 A MX9601756 A MX 9601756A MX 9601756 A MX9601756 A MX 9601756A MX 9601756 A MX9601756 A MX 9601756A
Authority
MX
Mexico
Prior art keywords
composition
urate
preparationm
oxidase
stable liquid
Prior art date
Application number
MX9601756A
Other languages
English (en)
Other versions
MXPA96001756A (es
Inventor
Claude Aleman
Alain Bayol
Thierry Breul
Patrice Dupin
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX9601756A publication Critical patent/MX9601756A/es
Publication of MXPA96001756A publication Critical patent/MXPA96001756A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/443—Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invencion se refiere a una composicion líquida farmacéuticamente aceptable, físicamente estable, que contiene urato-oxidasa, y de 0.1 mg/ml a 10 mg/ml de Poloxamer 188, en medio acuoso amortiguado. Esta composicion puede ser obtenida mediante disolucion de un liofilizado en un solvente acuoso.
MXPA/A/1996/001756A 1995-05-11 1996-05-09 Composicion liquida estable que contiene urato-oxidasa, y composicion liofilizada para supreparacion MXPA96001756A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9505606A FR2733914B1 (fr) 1995-05-11 1995-05-11 Composition de liquide stable contenant de l'urate oxydase et composition lyophilisee pour sa preparation
FR9505606 1995-05-11
US08/644,163 US5811096A (en) 1995-05-11 1996-05-10 Stable liquid composition containing urate oxidase and lyophilized composition for its preparation

Publications (2)

Publication Number Publication Date
MX9601756A true MX9601756A (es) 1997-07-31
MXPA96001756A MXPA96001756A (es) 1997-12-01

Family

ID=

Also Published As

Publication number Publication date
TW420614B (en) 2001-02-01
CA2175971C (en) 2003-12-30
AU5213996A (en) 1996-11-21
DE69604009D1 (de) 1999-10-07
EA000024B1 (ru) 1997-12-30
HUP9601241A2 (en) 1997-04-28
DE69604009T2 (de) 2000-04-06
JP2950775B2 (ja) 1999-09-20
PL314147A1 (en) 1996-11-12
NZ286554A (en) 1998-09-24
GR3031896T3 (en) 2000-02-29
NO961915L (no) 1996-11-12
FR2733914B1 (fr) 1997-08-01
HUP9601241A3 (en) 2000-06-28
SI0742013T1 (en) 1999-12-31
EP0742013A1 (fr) 1996-11-13
HU9601241D0 (en) 1996-07-29
FR2733914A1 (fr) 1996-11-15
EP0742013B1 (fr) 1999-09-01
PL184135B1 (pl) 2002-09-30
BR1100337A (pt) 2000-07-25
SG42355A1 (en) 1997-08-15
US5811096A (en) 1998-09-22
EA199600024A2 (ru) 1996-12-30
CZ290799B6 (cs) 2002-10-16
ZA963683B (en) 1997-11-10
ES2137635T3 (es) 1999-12-16
JPH0925242A (ja) 1997-01-28
HU225147B1 (en) 2006-07-28
EA199600024A3 (ru) 1997-03-31
NO315261B1 (no) 2003-08-11
DK0742013T3 (da) 2000-03-06
CN1147961A (zh) 1997-04-23
NO961915D0 (no) 1996-05-10
IL118171A (en) 2000-08-31
CZ135096A3 (en) 1996-12-11
IL118171A0 (en) 1996-09-12
ATE183925T1 (de) 1999-09-15
CA2175971A1 (en) 1996-11-12
CN1090972C (zh) 2002-09-18
AU710288B2 (en) 1999-09-16

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