HUP0402069A3 - Human papillomavirus e2 transactivation domain/inhibitor co-crystal and x-ray coordinates defining the ihnibitor-binding pocket - Google Patents
Human papillomavirus e2 transactivation domain/inhibitor co-crystal and x-ray coordinates defining the ihnibitor-binding pocketInfo
- Publication number
- HUP0402069A3 HUP0402069A3 HU0402069A HUP0402069A HUP0402069A3 HU P0402069 A3 HUP0402069 A3 HU P0402069A3 HU 0402069 A HU0402069 A HU 0402069A HU P0402069 A HUP0402069 A HU P0402069A HU P0402069 A3 HUP0402069 A3 HU P0402069A3
- Authority
- HU
- Hungary
- Prior art keywords
- ihnibitor
- inhibitor
- crystal
- binding pocket
- human papillomavirus
- Prior art date
Links
- 101000742658 Human papillomavirus type 1 Regulatory protein E2 Proteins 0.000 title 1
- 239000013078 crystal Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000023603 positive regulation of transcription initiation, DNA-dependent Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Laminated Bodies (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30441201P | 2001-07-12 | 2001-07-12 | |
| PCT/CA2002/001058 WO2003006495A2 (en) | 2001-07-12 | 2002-07-12 | Human papillomavirus e2 transactivation domain/inhibitor co-crystal and x-ray coordinates defining the inhibitor-binding pocket |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0402069A2 HUP0402069A2 (hu) | 2005-01-28 |
| HUP0402069A3 true HUP0402069A3 (en) | 2012-09-28 |
Family
ID=23176405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0402069A HUP0402069A3 (en) | 2001-07-12 | 2002-07-12 | Human papillomavirus e2 transactivation domain/inhibitor co-crystal and x-ray coordinates defining the ihnibitor-binding pocket |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7167801B2 (hu) |
| EP (2) | EP1409525B1 (hu) |
| JP (1) | JP4602665B2 (hu) |
| AT (2) | ATE343588T1 (hu) |
| AU (1) | AU2002317122B2 (hu) |
| CA (1) | CA2448482C (hu) |
| DE (2) | DE60215658T2 (hu) |
| DK (2) | DK1409525T3 (hu) |
| ES (2) | ES2274051T3 (hu) |
| HU (1) | HUP0402069A3 (hu) |
| IL (2) | IL159150A0 (hu) |
| MX (1) | MXPA04000271A (hu) |
| NZ (1) | NZ531068A (hu) |
| WO (1) | WO2003006495A2 (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2565308A1 (en) * | 2003-05-06 | 2004-11-25 | New Century Pharmaceuticals | Albumin binding sites for evaluating drug interactions and methods of evaluating or designing drugs based on their albumin binding properties |
| ATE447610T1 (de) * | 2003-05-26 | 2009-11-15 | Biotie Therapies Corp | Kristalliner vap-1 und verwendung |
| EP1684705A4 (en) * | 2003-11-03 | 2008-02-20 | New Century Pharmaceuticals | ALBUMIN BINDING FACILITIES FOR THE EVALUATION OF MEDICAMENTAL INTERACTION EFFECTS AND METHOD FOR ASSESSING OR DESIGNING MEDICAMENT BASED ON THEIR ALBUMIN BONDING PROPERTIES |
| US20090118301A1 (en) * | 2007-11-02 | 2009-05-07 | Arbor Vita Corporation | Compositions and Methods for Treating Cancer |
| CN112891520A (zh) * | 2021-04-13 | 2021-06-04 | 吉林省国大生物工程有限公司 | 一种预防和控制人乳头瘤病毒感染（hpv）的活性生物蛋白的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07500245A (ja) * | 1991-10-11 | 1995-01-12 | カイロン コーポレーション | パピローマウイルスの複製の阻害剤を同定する方法および組成物 |
| HUP0101396A3 (en) | 1998-05-01 | 2006-03-28 | Boehringer Ingelheim Ca Ltd | Preparation of human papillomavirus e1 having helicase activity and method therefor |
| ATE235509T1 (de) | 1998-06-30 | 2003-04-15 | Deutsches Krebsforsch | Peptide zur inhibition von hpv e7 proteinen |
| WO2000075182A1 (fr) * | 1999-06-04 | 2000-12-14 | Akira Kaji | Cristal de proteine du facteur de recyclage ribosomique (rrf) et son application sur la base de donnees de structure tridimensionnelles provenant du cristal |
| GB9921938D0 (en) | 1999-09-17 | 1999-11-17 | Univ York | Target for antiviral therapy |
| CA2389569A1 (en) * | 1999-11-16 | 2001-05-25 | Vertex Pharmaceuticals Incorporated | Crystallizable compositions comprising a caspase-7 |
| ATE357447T1 (de) | 2000-12-18 | 2007-04-15 | Boehringer Ingelheim Ca Ltd | Inhibitoren des papilloma-virus |
-
2002
- 2002-07-11 US US10/193,460 patent/US7167801B2/en not_active Expired - Lifetime
- 2002-07-12 DE DE60215658T patent/DE60215658T2/de not_active Expired - Lifetime
- 2002-07-12 ES ES02745024T patent/ES2274051T3/es not_active Expired - Lifetime
- 2002-07-12 IL IL15915002A patent/IL159150A0/xx unknown
- 2002-07-12 ES ES06012247T patent/ES2342309T3/es not_active Expired - Lifetime
- 2002-07-12 AU AU2002317122A patent/AU2002317122B2/en not_active Ceased
- 2002-07-12 DE DE60236114T patent/DE60236114D1/de not_active Expired - Lifetime
- 2002-07-12 EP EP02745024A patent/EP1409525B1/en not_active Expired - Lifetime
- 2002-07-12 CA CA2448482A patent/CA2448482C/en not_active Expired - Fee Related
- 2002-07-12 NZ NZ531068A patent/NZ531068A/en not_active IP Right Cessation
- 2002-07-12 JP JP2003512265A patent/JP4602665B2/ja not_active Expired - Fee Related
- 2002-07-12 EP EP06012247A patent/EP1695980B1/en not_active Expired - Lifetime
- 2002-07-12 DK DK02745024T patent/DK1409525T3/da active
- 2002-07-12 AT AT02745024T patent/ATE343588T1/de active
- 2002-07-12 AT AT06012247T patent/ATE465414T1/de active
- 2002-07-12 DK DK06012247.0T patent/DK1695980T3/da active
- 2002-07-12 HU HU0402069A patent/HUP0402069A3/hu unknown
- 2002-07-12 WO PCT/CA2002/001058 patent/WO2003006495A2/en active IP Right Grant
- 2002-07-12 MX MXPA04000271A patent/MXPA04000271A/es active IP Right Grant
-
2003
- 2003-12-02 IL IL159150A patent/IL159150A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60215658T2 (de) | 2007-12-27 |
| MXPA04000271A (es) | 2005-03-07 |
| US7167801B2 (en) | 2007-01-23 |
| ES2274051T3 (es) | 2007-05-16 |
| ES2342309T3 (es) | 2010-07-05 |
| DK1695980T3 (da) | 2010-08-02 |
| JP4602665B2 (ja) | 2010-12-22 |
| ATE343588T1 (de) | 2006-11-15 |
| CA2448482A1 (en) | 2003-01-23 |
| EP1695980B1 (en) | 2010-04-21 |
| EP1695980A3 (en) | 2006-09-06 |
| IL159150A (en) | 2009-09-01 |
| HUP0402069A2 (hu) | 2005-01-28 |
| CA2448482C (en) | 2011-12-06 |
| EP1409525B1 (en) | 2006-10-25 |
| IL159150A0 (en) | 2004-06-01 |
| US20030082769A1 (en) | 2003-05-01 |
| DK1409525T3 (da) | 2007-02-05 |
| JP2005512954A (ja) | 2005-05-12 |
| NZ531068A (en) | 2006-06-30 |
| DE60215658D1 (de) | 2006-12-07 |
| WO2003006495A2 (en) | 2003-01-23 |
| EP1409525A2 (en) | 2004-04-21 |
| EP1695980A2 (en) | 2006-08-30 |
| DE60236114D1 (de) | 2010-06-02 |
| AU2002317122B2 (en) | 2007-03-15 |
| WO2003006495A3 (en) | 2003-07-31 |
| ATE465414T1 (de) | 2010-05-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA200501913B (en) | New compounds for the inhibition of rotamases and use thereof | |
| SI1757606T1 (sl) | Ksantinski derivati za uporabo kot zdravila kot tudi postopek za njihovo pripravo | |
| HK1086488A1 (en) | Compound and use thereof for the treatment of cancer | |
| EP1572890A4 (en) | SLC7S AS MODULATORS OF THE P53 PATH AND METHOD OF USE | |
| AU1132102A (en) | Coated medical devices and sterilization thereof | |
| GB0116247D0 (en) | Surgical techniques and devices | |
| IL161134A0 (en) | Ester compound and medical use thereof | |
| EP1364957A4 (en) | GLYCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND THEIR MEDICAL USE | |
| GB0105613D0 (en) | Pharmaceutically effective compounds and their use | |
| AU2003273843A8 (en) | Use of skin-protecting substances | |
| ZA200210316B (en) | Composition and its therapeutic use. | |
| HUP0402069A3 (en) | Human papillomavirus e2 transactivation domain/inhibitor co-crystal and x-ray coordinates defining the ihnibitor-binding pocket | |
| AU2001267213A1 (en) | Cdna for human methylenetetrahydrofolate reductase and uses thereof | |
| SI1849468T1 (sl) | Farmacevtski sestavek, ki obsega roflumilast in levocetirizin | |
| GB0011052D0 (en) | Medical device and use thereof | |
| AU2003249930A1 (en) | Proteaseome inhibitors for the treatment of herpesviridae infected individuals | |
| GB0119025D0 (en) | Compounds and their therapeutic use | |
| GB0200258D0 (en) | Detection of human papillomavirus | |
| HUP0402061A3 (en) | Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, cox-2 inhibitor and a taxol | |
| EP1439845A4 (en) | INACTIVATION OF THE PAPILLOMA | |
| AU7402201A (en) | Use of substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compounds as medicaments | |
| AU2003220931A1 (en) | 2-pyrone compounds and use thereof | |
| IL162014A0 (en) | Shape-recovering material suitable for application of an attachment, and its use | |
| GB2376943B (en) | Compounds and their therapeutic use | |
| GB0112237D0 (en) | Compounds and their therapeutic use |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |