HUP0401584A2 - Mitogén aktivitású Bv8-nukleinsavak és polipeptidek - Google Patents

Mitogén aktivitású Bv8-nukleinsavak és polipeptidek

Info

Publication number
HUP0401584A2
HUP0401584A2 HU0401584A HUP0401584A HUP0401584A2 HU P0401584 A2 HUP0401584 A2 HU P0401584A2 HU 0401584 A HU0401584 A HU 0401584A HU P0401584 A HUP0401584 A HU P0401584A HU P0401584 A2 HUP0401584 A2 HU P0401584A2
Authority
HU
Hungary
Prior art keywords
polypeptides
nucleic acids
mitogenic activity
methods
endothelial cells
Prior art date
Application number
HU0401584A
Other languages
English (en)
Inventor
Napoleone Ferrara
Jennifer Le Couter
Original Assignee
Genentech Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc. filed Critical Genentech Inc.
Publication of HUP0401584A2 publication Critical patent/HUP0401584A2/hu
Publication of HUP0401584A3 publication Critical patent/HUP0401584A3/hu
Publication of HU230373B1 publication Critical patent/HU230373B1/hu

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5064—Endothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)

Abstract

A találmány tárgyát eljárások képezik Bv8-polipeptidek alkalmazásáraendotéliális sejtek proliferációjának az indukálására és endotéliálissejtek túlélésének fokozására. A találmány tárgyát képezik eljárásokBv8-aktivitás modulátorainak a szkrínelésére is. Ezenfelül a találmánytárgyát képezik kezelési eljárások Bv8-polipeptidek alkalmazásával. Ó
HU0401584A 2001-08-29 2002-08-27 Mitogén aktivitású Bv8-nukleinsavak és polipeptidek HU230373B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31618401P 2001-08-29 2001-08-29
US60/316,184 2001-08-29
PCT/US2002/027571 WO2003020892A2 (en) 2001-08-29 2002-08-27 Bv8 NUCLEIC ACIDS AND POLYPEPTIDES WITH MITOGENIC ACTIVITY

Publications (3)

Publication Number Publication Date
HUP0401584A2 true HUP0401584A2 (hu) 2004-11-29
HUP0401584A3 HUP0401584A3 (en) 2006-01-30
HU230373B1 HU230373B1 (hu) 2016-03-29

Family

ID=23227889

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401584A HU230373B1 (hu) 2001-08-29 2002-08-27 Mitogén aktivitású Bv8-nukleinsavak és polipeptidek

Country Status (22)

Country Link
US (3) US7060278B2 (hu)
EP (2) EP1427830B1 (hu)
JP (1) JP4361791B2 (hu)
KR (3) KR101008785B1 (hu)
CN (2) CN1575338B (hu)
AT (1) ATE557092T1 (hu)
AU (1) AU2002332732B2 (hu)
BR (1) BR0212070A (hu)
CA (1) CA2458670C (hu)
DK (1) DK1427830T3 (hu)
ES (1) ES2386346T3 (hu)
HK (1) HK1065565A1 (hu)
HU (1) HU230373B1 (hu)
IL (4) IL160422A0 (hu)
IS (1) IS2889B (hu)
MX (1) MXPA04001720A (hu)
NO (2) NO332445B1 (hu)
NZ (2) NZ530985A (hu)
PL (1) PL368972A1 (hu)
SI (1) SI1427830T1 (hu)
WO (1) WO2003020892A2 (hu)
ZA (1) ZA200401001B (hu)

Families Citing this family (14)

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ES2386346T3 (es) * 2001-08-29 2012-08-17 Genentech, Inc. Ácidos nucleicos y polipéptidos Bv8 con actividad mitógena
WO2003040326A2 (en) * 2001-11-02 2003-05-15 Nuvelo, Inc. Methods and materials relating to prokineticin-like polypeptides and polynucleotides
EP2526960A1 (en) * 2003-03-12 2012-11-28 Genentech, Inc. Use of BV8 and/or EG-VEGF to promote hematopoiesis
GB0320238D0 (en) 2003-08-29 2003-10-01 Medical Res Council Treatment of disease
WO2005042717A2 (en) * 2003-10-31 2005-05-12 The Regents Of The University Of California Primate prokineticin and prokineticin receptor polypeptides, related compositions and methods
CA2562969A1 (en) * 2004-03-29 2005-10-20 Janssen Pharmaceutica N.V. Prokineticin 2beta peptide and its use
US7872430B2 (en) * 2005-11-18 2011-01-18 Cree, Inc. Solid state lighting panels with variable voltage boost current sources
CA2648925A1 (en) * 2006-04-13 2007-10-25 Zymogenetics, Inc. Tetramerizing polypeptides and methods of use
WO2007124283A2 (en) * 2006-04-13 2007-11-01 Zymogenetics, Inc. Tetramerizing polypeptides and methods of use
US20100075377A1 (en) * 2006-04-13 2010-03-25 West James W Tetramerizing polypeptides and methods of use
CL2008002782A1 (es) * 2007-09-21 2009-07-31 Genentech Inc Anticuerpo anti-bv8 neutralizante; composicion que lo comprende; y su uso para tratar tumores en humanos previamente tratados con un antagonista del factor de crecimiento endotelial vascular.
KR101044874B1 (ko) * 2008-12-02 2011-06-28 주식회사 동호 흡인식 쓰레기 설비의 이송관로 막힘 검출 시스템
CN103068849B (zh) 2009-12-23 2016-04-06 霍夫曼-拉罗奇有限公司 抗Bv8抗体及其用途
KR101040724B1 (ko) * 2010-08-16 2011-06-10 주식회사 에스더블 테크 공기이송 더스트 배출장치

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Also Published As

Publication number Publication date
KR20100020531A (ko) 2010-02-22
IS7154A (is) 2004-02-13
JP4361791B2 (ja) 2009-11-11
US20060204510A1 (en) 2006-09-14
IL160422A (en) 2012-02-29
DK1427830T3 (da) 2012-07-23
IS2889B (is) 2014-07-15
KR101008734B1 (ko) 2011-01-14
CA2458670C (en) 2016-08-23
EP2311960A2 (en) 2011-04-20
NO20040553L (no) 2004-04-22
PL368972A1 (en) 2005-04-04
ATE557092T1 (de) 2012-05-15
EP1427830B1 (en) 2012-05-09
KR100942880B1 (ko) 2010-02-17
US7060278B2 (en) 2006-06-13
NO332445B1 (no) 2012-09-17
KR20090068301A (ko) 2009-06-25
US20030092623A1 (en) 2003-05-15
NO20120612L (no) 2004-04-22
JP2005504532A (ja) 2005-02-17
ZA200401001B (en) 2004-10-18
SI1427830T1 (sl) 2012-08-31
BR0212070A (pt) 2004-09-28
KR101008785B1 (ko) 2011-01-14
MXPA04001720A (es) 2004-05-31
CN1575338A (zh) 2005-02-02
CA2458670A1 (en) 2003-03-13
CN1575338B (zh) 2012-05-16
IL160422A0 (en) 2004-07-25
IL197539A (en) 2012-02-29
ES2386346T3 (es) 2012-08-17
WO2003020892A3 (en) 2004-02-26
EP1427830A2 (en) 2004-06-16
HK1065565A1 (en) 2005-02-25
NZ543755A (en) 2008-04-30
EP1427830A4 (en) 2005-08-17
US20070244063A1 (en) 2007-10-18
HU230373B1 (hu) 2016-03-29
US7811984B2 (en) 2010-10-12
CN101884784B (zh) 2014-03-12
KR20040030166A (ko) 2004-04-08
IL204543A (en) 2014-12-31
WO2003020892A2 (en) 2003-03-13
NZ530985A (en) 2006-03-31
NO334713B1 (no) 2014-05-12
CN101884784A (zh) 2010-11-17
EP2311960A3 (en) 2011-06-01
HUP0401584A3 (en) 2006-01-30
AU2002332732B2 (en) 2007-08-30

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