ATE238047T1 - Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerz - Google Patents
Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerzInfo
- Publication number
- ATE238047T1 ATE238047T1 AT98941201T AT98941201T ATE238047T1 AT E238047 T1 ATE238047 T1 AT E238047T1 AT 98941201 T AT98941201 T AT 98941201T AT 98941201 T AT98941201 T AT 98941201T AT E238047 T1 ATE238047 T1 AT E238047T1
- Authority
- AT
- Austria
- Prior art keywords
- phenylcarbamoylmethyl
- bis
- derivatives
- treatment
- dimethylammonium chloride
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5631297P | 1997-09-03 | 1997-09-03 | |
PCT/CA1998/000842 WO1999011252A2 (en) | 1997-09-03 | 1998-09-03 | N,n-bis (phenylcarbamoylmethyl) dimethylammonium chloride and derivatives in the treatment of pain |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE238047T1 true ATE238047T1 (de) | 2003-05-15 |
Family
ID=22003584
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98941201T ATE238047T1 (de) | 1997-09-03 | 1998-09-03 | Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerz |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1009397B1 (de) |
JP (1) | JP2001514216A (de) |
CN (1) | CN1276722A (de) |
AT (1) | ATE238047T1 (de) |
AU (1) | AU8970198A (de) |
BR (1) | BR9812182A (de) |
CA (1) | CA2303815A1 (de) |
DE (1) | DE69813839T2 (de) |
ES (1) | ES2197500T3 (de) |
HK (1) | HK1028957A1 (de) |
TW (1) | TW536401B (de) |
WO (1) | WO1999011252A2 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ507169A (en) | 1998-04-01 | 2004-02-27 | Cardiome Pharma Corp | Aminocyclohexyl ether compounds and uses thereof |
BR9911094A (pt) * | 1998-06-09 | 2001-10-30 | Nortran Pharmaceuticals Inc | Composições e métodos para o tratamento detosse |
US7507545B2 (en) | 1999-03-31 | 2009-03-24 | Cardiome Pharma Corp. | Ion channel modulating activity method |
US7057053B2 (en) | 2000-10-06 | 2006-06-06 | Cardiome Pharma Corp. | Ion channel modulating compounds and uses thereof |
US7524879B2 (en) | 2000-10-06 | 2009-04-28 | Cardiome Pharma Corp. | Ion channel modulating compounds and uses thereof |
BRPI0318278B8 (pt) | 2003-05-02 | 2024-01-09 | Cardiome Pharma Corp | Compostos de éter aminocicloexílico, composição compreendendo ditos compostos, usos dos mesmos e método para modular a atividade do canal iônico em um ambiente in vitro |
US7345086B2 (en) | 2003-05-02 | 2008-03-18 | Cardiome Pharma Corp. | Uses of ion channel modulating compounds |
WO2005018635A2 (en) | 2003-08-07 | 2005-03-03 | Cardiome Pharma Corp. | Ion channel modulating activity i |
US7345087B2 (en) | 2003-10-31 | 2008-03-18 | Cardiome Pharma Corp. | Aminocyclohexyl ether compounds and uses thereof |
WO2005097087A2 (en) | 2004-04-01 | 2005-10-20 | Cardiome Pharma Corp. | Merged ion channel modulating compounds and uses thereof |
WO2005113011A2 (en) | 2004-04-01 | 2005-12-01 | Cardiome Pharma Corp. | Prodrugs of ion channel modulating compounds and uses thereof |
US8263638B2 (en) | 2004-11-08 | 2012-09-11 | Cardiome Pharma Corp. | Dosing regimens for ion channel modulating compounds |
EP2101819B1 (de) | 2006-11-20 | 2013-01-09 | President and Fellows of Harvard College | Verfahren, zusammensetzungen und sets zur behandlung von schmerzen und pruritis |
CN102725401A (zh) | 2009-07-10 | 2012-10-10 | 哈佛大学校长及研究员协会 | 作为抗炎药的永久带电荷的钠和钙通道阻断剂 |
JP6833811B2 (ja) | 2015-08-03 | 2021-02-24 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 荷電イオンチャネル遮断薬及び使用方法 |
JP2022527690A (ja) | 2019-03-11 | 2022-06-03 | ノシオン セラピューティクス,インコーポレイテッド | 荷電したイオンチャンネル遮断薬および使用方法 |
US10828287B2 (en) | 2019-03-11 | 2020-11-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
CN113811305A (zh) | 2019-03-11 | 2021-12-17 | 诺西恩医疗公司 | 带电的离子通道阻滞剂及其使用方法 |
CA3129089A1 (en) | 2019-03-11 | 2020-09-17 | Bridget Mccarthy Cole | Ester substituted ion channel blockers and methods for use |
US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
US10933055B1 (en) | 2019-11-06 | 2021-03-02 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
WO2021091585A1 (en) | 2019-11-06 | 2021-05-14 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
CA3170070A1 (en) | 2020-03-11 | 2021-09-16 | Bridget Mccarthy Cole | Charged ion channel blockers and methods for use |
WO2023100836A1 (ja) * | 2021-11-30 | 2023-06-08 | マルホ株式会社 | 医薬組成物 |
JP7273257B1 (ja) * | 2021-11-30 | 2023-05-12 | マルホ株式会社 | 医薬組成物 |
-
1998
- 1998-08-31 TW TW087114395A patent/TW536401B/zh active
- 1998-09-03 WO PCT/CA1998/000842 patent/WO1999011252A2/en active IP Right Grant
- 1998-09-03 BR BR9812182-0A patent/BR9812182A/pt not_active IP Right Cessation
- 1998-09-03 AU AU89701/98A patent/AU8970198A/en not_active Abandoned
- 1998-09-03 CA CA002303815A patent/CA2303815A1/en not_active Abandoned
- 1998-09-03 ES ES98941201T patent/ES2197500T3/es not_active Expired - Lifetime
- 1998-09-03 EP EP98941201A patent/EP1009397B1/de not_active Expired - Lifetime
- 1998-09-03 CN CN98810388A patent/CN1276722A/zh active Pending
- 1998-09-03 AT AT98941201T patent/ATE238047T1/de not_active IP Right Cessation
- 1998-09-03 JP JP2000508355A patent/JP2001514216A/ja active Pending
- 1998-09-03 DE DE69813839T patent/DE69813839T2/de not_active Expired - Fee Related
-
2000
- 2000-12-15 HK HK00108104A patent/HK1028957A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1009397A2 (de) | 2000-06-21 |
ES2197500T3 (es) | 2004-01-01 |
CA2303815A1 (en) | 1999-03-11 |
HK1028957A1 (en) | 2001-03-16 |
TW536401B (en) | 2003-06-11 |
BR9812182A (pt) | 2002-01-15 |
WO1999011252A3 (en) | 1999-05-06 |
WO1999011252A2 (en) | 1999-03-11 |
EP1009397B1 (de) | 2003-04-23 |
JP2001514216A (ja) | 2001-09-11 |
DE69813839T2 (de) | 2004-03-04 |
DE69813839D1 (de) | 2003-05-28 |
CN1276722A (zh) | 2000-12-13 |
AU8970198A (en) | 1999-03-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE238047T1 (de) | Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerz | |
DE59609235D1 (de) | Verwendung von aerogelen in der landwirtschaft | |
DE69941586D1 (de) | Verwendung von Uridin in Kombination mit Cholin zur Behandlung von Gedächtnisstörungen | |
DE3483040D1 (de) | Maschinelesbares dokument und dessen behandlung. | |
ATE256463T1 (de) | Pharmazeutische zubereitung zur verwendung in der behandlung von diabetes | |
DE69927971D1 (de) | Verwendung von peg-ifn-alpha und ribavirin zur behandlung chronischer hepatitis c | |
DE69230046T2 (de) | 2-Bromomelatonin zur Behandlung von Schlafstörungen | |
DE69739758D1 (de) | Vakzine zur behandlung von lymphomen und leukämie | |
ATE246197T1 (de) | Neue heteroaromatische fructose 1,6- bisphosphatase inhibitoren | |
DE60321929D1 (de) | Pharmazeutische zusammensetzungen mit dextromethorphan und chinidin zur behandlung von neurologischen erkrankungen | |
DE3777812D1 (de) | T-gatterelektrode fuer feldeffekttransistor und dadurch hergestellter feldeffekttransistor. | |
ATE81978T1 (de) | Verwendung von 3'-azido-3'-deoxythymidin zur behandlung oder vorbeugung von menschlichen retrovirus-infektionen. | |
DE69421778D1 (de) | Verwendung von wirksamen Mengen von aktiven Stoffen zur Behandlung von Mischhaut | |
DE69212620T2 (de) | Verwendung von Glycosaminoglycanen zur Behandlung von diabetischer Nephropathie und diabetischer Neuropathie | |
GR3006073T3 (de) | ||
IS5504A (is) | Samsetning virk við meðhöndlun á getuleysi | |
ATE292975T1 (de) | Verwendung von tetrahydolipstatin in der behandlung von diabetes typ ii | |
DE50007706D1 (de) | Verwendung von melatonin zur behandlung der androgenetischen und diffusen alopezie vom weiblichen typ | |
DE3850433D1 (de) | Allergiebehandlung und Zusammensetzung dafür. | |
DE60027429D1 (de) | Dihydrobenzodiazepinen und deren verwendung zur behandlung von dyslipidämien | |
BR0014372A (pt) | Derivados de 5-hidroxissapogenina com atividade antidemência | |
FI973185A0 (fi) | Melatoniinin käyttö lääkeriippuvuudesta kärsivien potilaiden hoitoon | |
DE69936779D1 (de) | Verwendung von ngali nussöl zur behandlung/linderung der arthritisschmerzen und anderer ähnlichen störungen | |
DE69300037T2 (de) | Verwendung von Bucillamin zur Herstellung eines Arzneimittels zur Behandlung von Cystinuria. | |
DE69110861T2 (de) | Mittel zur verbesserung des kollagenmetabolismus und dessen verwendung. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |