ATE238047T1 - Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerz - Google Patents
Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerzInfo
- Publication number
- ATE238047T1 ATE238047T1 AT98941201T AT98941201T ATE238047T1 AT E238047 T1 ATE238047 T1 AT E238047T1 AT 98941201 T AT98941201 T AT 98941201T AT 98941201 T AT98941201 T AT 98941201T AT E238047 T1 ATE238047 T1 AT E238047T1
- Authority
- AT
- Austria
- Prior art keywords
- phenylcarbamoylmethyl
- bis
- derivatives
- treatment
- dimethylammonium chloride
- Prior art date
Links
- 208000002193 Pain Diseases 0.000 title abstract 2
- YGCONRRHHMKQRL-UHFFFAOYSA-N bis(2-anilino-2-oxoethyl)-dimethylazanium;chloride Chemical compound [Cl-].C=1C=CC=CC=1NC(=O)C[N+](C)(C)CC(=O)NC1=CC=CC=C1 YGCONRRHHMKQRL-UHFFFAOYSA-N 0.000 title abstract 2
- 208000000094 Chronic Pain Diseases 0.000 title 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000002483 medication Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5631297P | 1997-09-03 | 1997-09-03 | |
| PCT/CA1998/000842 WO1999011252A2 (en) | 1997-09-03 | 1998-09-03 | N,n-bis (phenylcarbamoylmethyl) dimethylammonium chloride and derivatives in the treatment of pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE238047T1 true ATE238047T1 (de) | 2003-05-15 |
Family
ID=22003584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98941201T ATE238047T1 (de) | 1997-09-03 | 1998-09-03 | Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerz |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1009397B1 (de) |
| JP (1) | JP2001514216A (de) |
| CN (1) | CN1276722A (de) |
| AT (1) | ATE238047T1 (de) |
| AU (1) | AU8970198A (de) |
| BR (1) | BR9812182A (de) |
| CA (1) | CA2303815A1 (de) |
| DE (1) | DE69813839T2 (de) |
| ES (1) | ES2197500T3 (de) |
| TW (1) | TW536401B (de) |
| WO (1) | WO1999011252A2 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK285908B6 (sk) | 1998-04-01 | 2007-10-04 | Nortran Pharmaceuticals Inc. | Aminocyklohexyléterová zlúčenina, kompozícia obsahujúca túto zlúčeninu, použitie tejto zlúčeniny pri výrobe liečiva a pri liečbe |
| WO1999063985A1 (en) * | 1998-06-09 | 1999-12-16 | Nortran Pharmaceuticals, Inc. | Compositions and methods for treatment of cough |
| US7507545B2 (en) | 1999-03-31 | 2009-03-24 | Cardiome Pharma Corp. | Ion channel modulating activity method |
| US7524879B2 (en) | 2000-10-06 | 2009-04-28 | Cardiome Pharma Corp. | Ion channel modulating compounds and uses thereof |
| US7057053B2 (en) | 2000-10-06 | 2006-06-06 | Cardiome Pharma Corp. | Ion channel modulating compounds and uses thereof |
| US7345086B2 (en) | 2003-05-02 | 2008-03-18 | Cardiome Pharma Corp. | Uses of ion channel modulating compounds |
| ES2264776T3 (es) | 2003-05-02 | 2007-01-16 | Cardiome Pharma Corp. | Compuestos de aminociclohexil eter y sus usos. |
| WO2005018635A2 (en) | 2003-08-07 | 2005-03-03 | Cardiome Pharma Corp. | Ion channel modulating activity i |
| US7345087B2 (en) | 2003-10-31 | 2008-03-18 | Cardiome Pharma Corp. | Aminocyclohexyl ether compounds and uses thereof |
| WO2005113011A2 (en) | 2004-04-01 | 2005-12-01 | Cardiome Pharma Corp. | Prodrugs of ion channel modulating compounds and uses thereof |
| US8058304B2 (en) | 2004-04-01 | 2011-11-15 | Cardiome Pharma Corp. | Merged ion channel modulating compounds and uses thereof |
| US8263638B2 (en) | 2004-11-08 | 2012-09-11 | Cardiome Pharma Corp. | Dosing regimens for ion channel modulating compounds |
| EP2446903B1 (de) | 2006-11-20 | 2019-10-09 | President and Fellows of Harvard College | Zusammensetzungen zur Behandlung von Juckreiz |
| US20120172429A1 (en) | 2009-07-10 | 2012-07-05 | Woolf Clifford J | Permanently charged sodium and calcium channel blockers as anti- inflammatory agents |
| US11021443B2 (en) | 2015-08-03 | 2021-06-01 | President And Fellows Of Harvard College | Charged ion channel blockers and methods for use |
| US10786485B1 (en) | 2019-03-11 | 2020-09-29 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| JP7692834B2 (ja) | 2019-03-11 | 2025-06-16 | ノシオン セラピューティクス，インコーポレイテッド | 荷電したイオンチャンネル遮断薬および使用方法 |
| CA3129111A1 (en) | 2019-03-11 | 2020-09-17 | Bridget M. Cole | Charged ion channel blockers and methods for use |
| MA55320A (fr) | 2019-03-11 | 2022-01-19 | Nocion Therapeutics Inc | Bloqueurs de canaux ioniques substitués par un ester et méthodes d'utilisation |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10933055B1 (en) | 2019-11-06 | 2021-03-02 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| CN114828845A (zh) | 2019-11-06 | 2022-07-29 | 诺西恩医疗公司 | 带电的离子通道阻滞剂及其使用方法 |
| US12162851B2 (en) | 2020-03-11 | 2024-12-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| EP4118070A4 (de) | 2020-03-11 | 2024-04-10 | Nocion Therapeutics, Inc. | Geladene ionenkanalblocker und verfahren zur verwendung |
| WO2023100836A1 (ja) * | 2021-11-30 | 2023-06-08 | マルホ株式会社 | 医薬組成物 |
| CN118265526A (zh) * | 2021-11-30 | 2024-06-28 | 玛路弘株式会社 | 药物组合物 |
-
1998
- 1998-08-31 TW TW087114395A patent/TW536401B/zh active
- 1998-09-03 ES ES98941201T patent/ES2197500T3/es not_active Expired - Lifetime
- 1998-09-03 CN CN98810388A patent/CN1276722A/zh active Pending
- 1998-09-03 CA CA002303815A patent/CA2303815A1/en not_active Abandoned
- 1998-09-03 AT AT98941201T patent/ATE238047T1/de not_active IP Right Cessation
- 1998-09-03 AU AU89701/98A patent/AU8970198A/en not_active Abandoned
- 1998-09-03 JP JP2000508355A patent/JP2001514216A/ja active Pending
- 1998-09-03 DE DE69813839T patent/DE69813839T2/de not_active Expired - Fee Related
- 1998-09-03 BR BR9812182-0A patent/BR9812182A/pt not_active IP Right Cessation
- 1998-09-03 WO PCT/CA1998/000842 patent/WO1999011252A2/en not_active Ceased
- 1998-09-03 EP EP98941201A patent/EP1009397B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU8970198A (en) | 1999-03-22 |
| JP2001514216A (ja) | 2001-09-11 |
| HK1028957A1 (en) | 2001-03-16 |
| EP1009397A2 (de) | 2000-06-21 |
| TW536401B (en) | 2003-06-11 |
| WO1999011252A2 (en) | 1999-03-11 |
| DE69813839T2 (de) | 2004-03-04 |
| EP1009397B1 (de) | 2003-04-23 |
| WO1999011252A3 (en) | 1999-05-06 |
| CN1276722A (zh) | 2000-12-13 |
| DE69813839D1 (de) | 2003-05-28 |
| ES2197500T3 (es) | 2004-01-01 |
| CA2303815A1 (en) | 1999-03-11 |
| BR9812182A (pt) | 2002-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |