ATE238047T1 - Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerz - Google Patents

Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerz

Info

Publication number
ATE238047T1
ATE238047T1 AT98941201T AT98941201T ATE238047T1 AT E238047 T1 ATE238047 T1 AT E238047T1 AT 98941201 T AT98941201 T AT 98941201T AT 98941201 T AT98941201 T AT 98941201T AT E238047 T1 ATE238047 T1 AT E238047T1
Authority
AT
Austria
Prior art keywords
phenylcarbamoylmethyl
bis
derivatives
treatment
dimethylammonium chloride
Prior art date
Application number
AT98941201T
Other languages
English (en)
Inventor
Bernard A Macleod
David M J Quastel
Original Assignee
Ucb Farchim Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Farchim Sa filed Critical Ucb Farchim Sa
Application granted granted Critical
Publication of ATE238047T1 publication Critical patent/ATE238047T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98941201T 1997-09-03 1998-09-03 Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerz ATE238047T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5631297P 1997-09-03 1997-09-03
PCT/CA1998/000842 WO1999011252A2 (en) 1997-09-03 1998-09-03 N,n-bis (phenylcarbamoylmethyl) dimethylammonium chloride and derivatives in the treatment of pain

Publications (1)

Publication Number Publication Date
ATE238047T1 true ATE238047T1 (de) 2003-05-15

Family

ID=22003584

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98941201T ATE238047T1 (de) 1997-09-03 1998-09-03 Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerz

Country Status (12)

Country Link
EP (1) EP1009397B1 (de)
JP (1) JP2001514216A (de)
CN (1) CN1276722A (de)
AT (1) ATE238047T1 (de)
AU (1) AU8970198A (de)
BR (1) BR9812182A (de)
CA (1) CA2303815A1 (de)
DE (1) DE69813839T2 (de)
ES (1) ES2197500T3 (de)
HK (1) HK1028957A1 (de)
TW (1) TW536401B (de)
WO (1) WO1999011252A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2326777C (en) 1998-04-01 2011-12-20 Nortran Pharmaceuticals Inc. Aminocyclohexyl ether compounds and uses thereof
CN1311673A (zh) * 1998-06-09 2001-09-05 诺特兰药品有限公司 治疗咳嗽的组合物和方法
US7507545B2 (en) 1999-03-31 2009-03-24 Cardiome Pharma Corp. Ion channel modulating activity method
US7057053B2 (en) 2000-10-06 2006-06-06 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
US7524879B2 (en) 2000-10-06 2009-04-28 Cardiome Pharma Corp. Ion channel modulating compounds and uses thereof
BRPI0318278B8 (pt) 2003-05-02 2024-01-09 Cardiome Pharma Corp Compostos de éter aminocicloexílico, composição compreendendo ditos compostos, usos dos mesmos e método para modular a atividade do canal iônico em um ambiente in vitro
US7345086B2 (en) 2003-05-02 2008-03-18 Cardiome Pharma Corp. Uses of ion channel modulating compounds
US7674820B2 (en) 2003-08-07 2010-03-09 Cardiome Pharma Corp. Ion channel modulating activity I
US7345087B2 (en) 2003-10-31 2008-03-18 Cardiome Pharma Corp. Aminocyclohexyl ether compounds and uses thereof
CA2561819A1 (en) 2004-04-01 2005-12-01 Cardiome Pharma Corp. Prodrugs of ion channel modulating compounds and uses thereof
WO2005097087A2 (en) 2004-04-01 2005-10-20 Cardiome Pharma Corp. Merged ion channel modulating compounds and uses thereof
JP5583325B2 (ja) 2004-11-08 2014-09-03 カーディオム ファーマ コーポレイション イオンチャネル調節化合物の投与レジメ
KR20090082507A (ko) 2006-11-20 2009-07-30 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 통증 및 소양증 치료용 방법, 조성물 및 키트
CA3027255C (en) 2009-07-10 2022-06-21 The General Hospital Corporation Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
JP6833811B2 (ja) 2015-08-03 2021-02-24 プレジデント アンド フェローズ オブ ハーバード カレッジ 荷電イオンチャネル遮断薬及び使用方法
CA3129089A1 (en) 2019-03-11 2020-09-17 Bridget Mccarthy Cole Ester substituted ion channel blockers and methods for use
CA3129117A1 (en) 2019-03-11 2020-09-17 Bridget Mccarthy Cole Charged ion channel blockers and methods for use
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
EP3937945A4 (de) 2019-03-11 2023-01-04 Nocion Therapeutics, Inc. Geladene ionenkanalblocker und verfahren zur verwendung
CA3155586A1 (en) 2019-11-06 2021-05-14 Bridget M. Cole Charged ion channel blockers and methods for use
EP4054586A4 (de) 2019-11-06 2023-11-22 Nocion Therapeutics, Inc. Geladene ionenkanalblocker und verfahren zur verwendung
CN115279731B (zh) 2020-03-11 2024-09-13 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法
WO2023100836A1 (ja) * 2021-11-30 2023-06-08 マルホ株式会社 医薬組成物
KR20240110799A (ko) * 2021-11-30 2024-07-16 마루호 코 엘티디 의약 조성물

Also Published As

Publication number Publication date
CN1276722A (zh) 2000-12-13
JP2001514216A (ja) 2001-09-11
TW536401B (en) 2003-06-11
CA2303815A1 (en) 1999-03-11
EP1009397A2 (de) 2000-06-21
ES2197500T3 (es) 2004-01-01
BR9812182A (pt) 2002-01-15
DE69813839T2 (de) 2004-03-04
AU8970198A (en) 1999-03-22
HK1028957A1 (en) 2001-03-16
DE69813839D1 (de) 2003-05-28
WO1999011252A2 (en) 1999-03-11
EP1009397B1 (de) 2003-04-23
WO1999011252A3 (en) 1999-05-06

Similar Documents

Publication Publication Date Title
ATE238047T1 (de) Verwendung von n,n-bis (phenylcarbamoylmethyl) dimethylammoniumchlorid und derivaten davon zur behandlung von chronischem schmerz
ATE217754T1 (de) Verwendung von aerogelen in der landwirtschaft
DE69941586D1 (de) Verwendung von Uridin in Kombination mit Cholin zur Behandlung von Gedächtnisstörungen
ATE349428T1 (de) Prostaglandinagoniste und deren verwendung zur behandlung von knochenerkrankungen
DE3483040D1 (de) Maschinelesbares dokument und dessen behandlung.
DE69631157D1 (de) Pharmazeutische Zubereitung zur Verwendung in der Behandlung von Diabetes
DE69328550D1 (de) Verwendung von fulleren-derivaten in diagnostischen und/oder therapeutischen mitteln
ATE184792T1 (de) 2-bromomelatonin zur behandlung von schlafstörungen
DE69739758D1 (de) Vakzine zur behandlung von lymphomen und leukämie
DE60321929D1 (de) Pharmazeutische zusammensetzungen mit dextromethorphan und chinidin zur behandlung von neurologischen erkrankungen
DE3777812D1 (de) T-gatterelektrode fuer feldeffekttransistor und dadurch hergestellter feldeffekttransistor.
ATE81978T1 (de) Verwendung von 3'-azido-3'-deoxythymidin zur behandlung oder vorbeugung von menschlichen retrovirus-infektionen.
DE69911221D1 (de) Methode und gerät zur darreichung von therapeutischen mitteln in verbindung mit dem plazieren von radioaktiven körnern
DE69034018D1 (de) Kombinierte verwendung von hyaluronsäure und therapeutischen wirkstoffen zur verbesserung des therapeutischen effekts
DE69830660D1 (de) Behandlung von atemstillstand im schlaf
DE69212620D1 (de) Verwendung von Glycosaminoglycanen zur Behandlung von diabetischer Nephropathie und diabetischer Neuropathie
DE60032795D1 (de) Nordihydroguaiaretinsäurederivate zur behandlung von tumoren
GR3006073T3 (de)
DE69829763D1 (de) Verwendung von tetrahydolipstatin in der behandlung von diabetes typ ii
DE50007706D1 (de) Verwendung von melatonin zur behandlung der androgenetischen und diffusen alopezie vom weiblichen typ
DE3850433D1 (de) Allergiebehandlung und Zusammensetzung dafür.
IS4628A (is) Frumuröð sem myndar kvalastillandi efni til nota í meðferð gegn sársauka
DE60027429D1 (de) Dihydrobenzodiazepinen und deren verwendung zur behandlung von dyslipidämien
BR0014372A (pt) Derivados de 5-hidroxissapogenina com atividade antidemência
ATA901396A (de) Verwendung von melatonin zur behandlung von an medikamentensucht leidenden patienten

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties