HUP0400886A2 - Koleszteril-észter transzfer protein inhibitorok és fibrinsav-származékok kombinációi szív-érrendszeri indikációkhoz - Google Patents

Koleszteril-észter transzfer protein inhibitorok és fibrinsav-származékok kombinációi szív-érrendszeri indikációkhoz

Info

Publication number
HUP0400886A2
HUP0400886A2 HU0400886A HUP0400886A HUP0400886A2 HU P0400886 A2 HUP0400886 A2 HU P0400886A2 HU 0400886 A HU0400886 A HU 0400886A HU P0400886 A HUP0400886 A HU P0400886A HU P0400886 A2 HUP0400886 A2 HU P0400886A2
Authority
HU
Hungary
Prior art keywords
transfer protein
inhibotors
combinations
ester transfer
fibric acid
Prior art date
Application number
HU0400886A
Other languages
English (en)
Inventor
Kevin C. Glenn
James A. Sikorski
Original Assignee
G.D. Searle Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by G.D. Searle Llc filed Critical G.D. Searle Llc
Publication of HUP0400886A2 publication Critical patent/HUP0400886A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)

Abstract

A találmány szív-érrendszeri terápiás vegyületek kombinációitismerteti szív-érrendszeri betegségek, ezen belülhiperkoleszterinémia, érszűkület vagy hiperlipidémia megelőzésére vagykezelésére. Az ismertetett kombinációk egy fibrinsavszármazékot és egykoleszteril-észter transzfer protein (CETP) inhibitort tartalmaznak. Ó
HU0400886A 1998-12-23 1999-12-17 Koleszteril-észter transzfer protein inhibitorok és fibrinsav-származékok kombinációi szív-érrendszeri indikációkhoz HUP0400886A2 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11395598P 1998-12-23 1998-12-23
US14261699P 1999-07-07 1999-07-07
PCT/US1999/027945 WO2000038724A1 (en) 1998-12-23 1999-12-17 Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications

Publications (1)

Publication Number Publication Date
HUP0400886A2 true HUP0400886A2 (hu) 2004-07-28

Family

ID=26811677

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0400886A HUP0400886A2 (hu) 1998-12-23 1999-12-17 Koleszteril-észter transzfer protein inhibitorok és fibrinsav-származékok kombinációi szív-érrendszeri indikációkhoz

Country Status (23)

Country Link
US (2) US6458850B1 (hu)
EP (2) EP1340509A1 (hu)
JP (1) JP2002533410A (hu)
KR (1) KR20010099937A (hu)
CN (1) CN1338944A (hu)
AT (1) ATE242009T1 (hu)
AU (1) AU776664B2 (hu)
BR (1) BR9916485A (hu)
CA (1) CA2356157C (hu)
CZ (1) CZ20012341A3 (hu)
DE (1) DE69908645T2 (hu)
DK (1) DK1140186T3 (hu)
EA (2) EA009466B1 (hu)
ES (1) ES2201827T3 (hu)
HK (2) HK1040925B (hu)
HU (1) HUP0400886A2 (hu)
IL (1) IL143949A0 (hu)
MX (1) MXPA01006469A (hu)
NO (1) NO20013158L (hu)
NZ (1) NZ512534A (hu)
PL (1) PL348503A1 (hu)
PT (1) PT1140186E (hu)
WO (1) WO2000038724A1 (hu)

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US7264813B2 (en) 2003-09-24 2007-09-04 Nikken Sohonsha Corporation Therapeutic uses of Dunaliella powder
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EP2927693A1 (en) 2004-10-06 2015-10-07 The Brigham and Women's Hospital Relevance of achieved levels of markers of systemic inflammation following treatment
CN1891823B (zh) * 2005-07-05 2011-03-30 北京诺赛基因组研究中心有限公司 具有特定单核苷酸多态性的cetp基因及其检测方法和用途
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JP2012171911A (ja) 2011-02-22 2012-09-10 Kao Corp Ｐｐａｒ活性化剤
CN104053441B (zh) * 2011-11-30 2016-04-20 株式会社大熊制药 用于预防或治疗高脂血症的药物组合物
WO2015195748A2 (en) 2014-06-17 2015-12-23 Ganiban Gary Devices and methods to provide hands free scleral depression during ophthalmic procedures
TWI691331B (zh) * 2014-09-26 2020-04-21 日商興和股份有限公司 脂質異常症治療劑

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Also Published As

Publication number Publication date
BR9916485A (pt) 2002-01-15
JP2002533410A (ja) 2002-10-08
IL143949A0 (en) 2002-04-21
EP1140186B1 (en) 2003-06-04
CA2356157A1 (en) 2000-07-06
US6458850B1 (en) 2002-10-01
CA2356157C (en) 2008-04-01
AU2157600A (en) 2000-07-31
WO2000038724A1 (en) 2000-07-06
CZ20012341A3 (cs) 2001-12-12
US20030166720A1 (en) 2003-09-04
NO20013158L (no) 2001-08-22
PT1140186E (pt) 2003-10-31
AU776664B2 (en) 2004-09-16
PL348503A1 (en) 2002-05-20
HK1040925A1 (en) 2002-06-28
NO20013158D0 (no) 2001-06-22
HK1045108A1 (zh) 2002-11-15
EA004231B1 (ru) 2004-02-26
MXPA01006469A (es) 2004-03-10
EA200100706A1 (ru) 2001-12-24
CN1338944A (zh) 2002-03-06
KR20010099937A (ko) 2001-11-09
NZ512534A (en) 2003-11-28
EP1140186A1 (en) 2001-10-10
ES2201827T3 (es) 2004-03-16
DE69908645T2 (de) 2004-05-13
ATE242009T1 (de) 2003-06-15
DK1140186T3 (da) 2003-09-29
EP1340509A1 (en) 2003-09-03
EA009466B1 (ru) 2007-12-28
DE69908645D1 (de) 2003-07-10
EA200300914A1 (ru) 2003-12-25
HK1040925B (zh) 2003-09-11

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