HUP0400067A2 - Dementia és neurodegeneratív betegségek kezelése közepes dózisú LHRH-antagonistával - Google Patents

Dementia és neurodegeneratív betegségek kezelése közepes dózisú LHRH-antagonistával

Info

Publication number
HUP0400067A2
HUP0400067A2 HU0400067A HUP0400067A HUP0400067A2 HU P0400067 A2 HUP0400067 A2 HU P0400067A2 HU 0400067 A HU0400067 A HU 0400067A HU P0400067 A HUP0400067 A HU P0400067A HU P0400067 A2 HUP0400067 A2 HU P0400067A2
Authority
HU
Hungary
Prior art keywords
dementia
treatment
neurodegenerative diseases
lhrh antagonists
intermediate doses
Prior art date
Application number
HU0400067A
Other languages
English (en)
Hungarian (hu)
Inventor
Jürgen Engel
Rainer Voegeli
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of HUP0400067A2 publication Critical patent/HUP0400067A2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
HU0400067A 2001-04-30 2002-04-27 Dementia és neurodegeneratív betegségek kezelése közepes dózisú LHRH-antagonistával HUP0400067A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28743401P 2001-04-30 2001-04-30
PCT/EP2002/004677 WO2002102401A1 (en) 2001-04-30 2002-04-27 Treatment of dementia and neurodegenerative diseases with intermediate doses of lhrh antagonists

Publications (1)

Publication Number Publication Date
HUP0400067A2 true HUP0400067A2 (hu) 2004-04-28

Family

ID=23102886

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0400067A HUP0400067A2 (hu) 2001-04-30 2002-04-27 Dementia és neurodegeneratív betegségek kezelése közepes dózisú LHRH-antagonistával

Country Status (27)

Country Link
US (1) US7288517B2 (cg-RX-API-DMAC7.html)
EP (1) EP1392348B1 (cg-RX-API-DMAC7.html)
JP (1) JP2004529207A (cg-RX-API-DMAC7.html)
KR (1) KR20040000446A (cg-RX-API-DMAC7.html)
CN (1) CN1317030C (cg-RX-API-DMAC7.html)
AT (1) ATE400287T1 (cg-RX-API-DMAC7.html)
AU (1) AU2002310788B2 (cg-RX-API-DMAC7.html)
BG (1) BG108339A (cg-RX-API-DMAC7.html)
BR (1) BR0209290A (cg-RX-API-DMAC7.html)
CA (1) CA2444876A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ20033167A3 (cg-RX-API-DMAC7.html)
DE (1) DE60227507D1 (cg-RX-API-DMAC7.html)
DK (1) DK1392348T3 (cg-RX-API-DMAC7.html)
ES (1) ES2307760T3 (cg-RX-API-DMAC7.html)
HU (1) HUP0400067A2 (cg-RX-API-DMAC7.html)
IL (1) IL156777A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA03008666A (cg-RX-API-DMAC7.html)
NO (1) NO20034322L (cg-RX-API-DMAC7.html)
NZ (1) NZ544417A (cg-RX-API-DMAC7.html)
PL (1) PL362319A1 (cg-RX-API-DMAC7.html)
PT (1) PT1392348E (cg-RX-API-DMAC7.html)
RU (1) RU2319501C2 (cg-RX-API-DMAC7.html)
SI (1) SI1392348T1 (cg-RX-API-DMAC7.html)
SK (1) SK14512003A3 (cg-RX-API-DMAC7.html)
UA (1) UA80679C2 (cg-RX-API-DMAC7.html)
WO (1) WO2002102401A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200305326B (cg-RX-API-DMAC7.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
US20020077327A1 (en) * 1999-09-23 2002-06-20 Neurocrine Biosciences, Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
EP1300398B1 (en) 2000-07-05 2006-04-05 Astellas Pharma Inc. Propane-1,3-dione derivatives
DE10137174A1 (de) * 2001-07-31 2003-02-13 Zentaris Ag Verwendung von LHRH-Antagonisten in nichtkastrierenden Dosen zur Verbesserung der T-Zellen-vermittelten Immunität
US7709519B2 (en) * 2004-06-04 2010-05-04 Astellas Pharma Inc. Benzimidazolylidene propane-1,3 dione derivative or salt thereof
US20080171736A1 (en) * 2004-12-23 2008-07-17 Gregory Christopher W Treatment of Alzheimer's Disease and Mild Cognitive impairment using GnRH-I analogs and one or more of acetylcholinesterase inhibitors and NMDA receptor antagonists
CA2590997A1 (en) * 2004-12-23 2006-07-06 Voyager Pharmaceutical Corporation Leuprolide acetate and acetylcholinesterase inhibitors or nmda receptor antagonists for the treatment of alzheimer`s disease
BRPI0609625A2 (pt) 2005-03-31 2010-04-20 Astellas Pharma Inc derivados de propano-1,3-diona ou sal destes
BRPI0717618A2 (pt) 2006-10-21 2013-10-22 Abbott Gmbh & Co Kg Compostos heterocíclicos e uso dos mesmos como inibidores de glicogênio sintase quinase 3
WO2009043437A2 (en) * 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
EP2187917A2 (en) * 2007-09-11 2010-05-26 Mondobiotech Laboratories AG Use of neuropeptide sf, alone or in combination with glp-2, as a therapeutic agent
EP2095818A1 (en) * 2008-02-29 2009-09-02 AEterna Zentaris GmbH Use of LHRH antagonists at non-castrating doses
US20110129532A1 (en) * 2008-05-29 2011-06-02 Isr Immune System Regulation Ab Method and means for treating viral disease, in particular hiv/aids
CN103119035B (zh) 2010-09-27 2015-09-30 雅培股份有限两合公司 杂环化合物和它们作为糖原合成酶激酶-3抑制剂的用途
US9090592B2 (en) 2010-12-30 2015-07-28 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
EP3560555A1 (en) * 2018-04-26 2019-10-30 LifeArc A composition for treating one or more estrogen related diseases
WO2025155903A1 (en) * 2024-01-19 2025-07-24 Temple University-Of The Commonwealth System Of Higher Education Compositions of antioxidant translation modulators for treating neurodegenerative disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3135743A (en) 1960-06-29 1964-06-02 Sterling Drug Inc Steroido[2. 3-d]isoxazoles and preparation thereof
EP0901489A1 (en) 1996-05-20 1999-03-17 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
DE19911771B4 (de) * 1999-03-17 2006-03-30 Zentaris Gmbh LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung
WO2000069859A1 (en) * 1999-05-14 2000-11-23 Neurocrine Biosciences, Inc. Imidazo- and pyrrolo[1,2-a]pyrimid-4-ones as gonadotropin-releasing hormone receptor antagonists
CA2309395A1 (en) * 1999-06-04 2000-12-04 Richard Lloyd Bowen Methods for preventing and treating alzheimer's disease
KR20020045609A (ko) * 1999-10-15 2002-06-19 추후기재 고나도트로핀-분비 호르몬 수용체 길항제 및 이와 관련된방법
WO2001078780A1 (en) 2000-04-13 2001-10-25 Takeda Chemical Industries, Ltd. Preventives/remedies for alzheimer's disease
EP1300398B1 (en) 2000-07-05 2006-04-05 Astellas Pharma Inc. Propane-1,3-dione derivatives

Also Published As

Publication number Publication date
CN1575185A (zh) 2005-02-02
JP2004529207A (ja) 2004-09-24
EP1392348B1 (en) 2008-07-09
NZ544417A (en) 2008-03-28
CZ20033167A3 (cs) 2004-08-18
US20020177556A1 (en) 2002-11-28
CA2444876A1 (en) 2002-12-27
PL362319A1 (en) 2004-10-18
CN1317030C (zh) 2007-05-23
ATE400287T1 (de) 2008-07-15
ZA200305326B (en) 2003-07-30
NO20034322D0 (no) 2003-09-26
US7288517B2 (en) 2007-10-30
WO2002102401A1 (en) 2002-12-27
RU2319501C2 (ru) 2008-03-20
IL156777A0 (en) 2004-02-08
EP1392348A1 (en) 2004-03-03
UA80679C2 (en) 2007-10-25
ES2307760T3 (es) 2008-12-01
PT1392348E (pt) 2008-09-09
MXPA03008666A (es) 2004-10-15
KR20040000446A (ko) 2004-01-03
DE60227507D1 (de) 2008-08-21
AU2002310788B2 (en) 2007-04-05
BG108339A (bg) 2004-11-30
DK1392348T3 (da) 2008-09-29
SK14512003A3 (sk) 2004-08-03
SI1392348T1 (sl) 2008-12-31
RU2003134949A (ru) 2005-02-10
BR0209290A (pt) 2004-07-13
NO20034322L (no) 2003-09-26
HK1072000A1 (en) 2005-08-12

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Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: ZENTARIS GMBH, DE

Free format text: FORMER OWNER(S): ZENTARIS GMBH, DE

FD9A Lapse of provisional protection due to non-payment of fees