HUP0304034A2 - Nikotin acetilkolin receptor ligandumokként és/vagy szerotonerg ligandumokként alkalmazható 6H-oxazolo[4,5-e]indol-származékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények - Google Patents
Nikotin acetilkolin receptor ligandumokként és/vagy szerotonerg ligandumokként alkalmazható 6H-oxazolo[4,5-e]indol-származékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények Download PDFInfo
- Publication number
- HUP0304034A2 HUP0304034A2 HU0304034A HUP0304034A HUP0304034A2 HU P0304034 A2 HUP0304034 A2 HU P0304034A2 HU 0304034 A HU0304034 A HU 0304034A HU P0304034 A HUP0304034 A HU P0304034A HU P0304034 A2 HUP0304034 A2 HU P0304034A2
- Authority
- HU
- Hungary
- Prior art keywords
- group
- oxazolo
- general formula
- compound
- indole
- Prior art date
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Landscapes
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Addiction (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10121217A DE10121217A1 (de) | 2001-04-30 | 2001-04-30 | 6H-Oxazolo[4,5-e]indol-Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden |
| PCT/EP2002/003784 WO2002088139A1 (en) | 2001-04-30 | 2002-04-05 | 6h-oxazolo[4,5-e]indole derivatives as nicotinic acetylcholine receptor ligands and/or serotonergic ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0304034A2 true HUP0304034A2 (hu) | 2004-04-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0304034A HUP0304034A2 (hu) | 2001-04-30 | 2002-04-05 | Nikotin acetilkolin receptor ligandumokként és/vagy szerotonerg ligandumokként alkalmazható 6H-oxazolo[4,5-e]indol-származékok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7291633B2 (https=) |
| EP (1) | EP1392699B1 (https=) |
| JP (1) | JP4485746B2 (https=) |
| AR (1) | AR033267A1 (https=) |
| AT (1) | ATE291026T1 (https=) |
| AU (1) | AU2002257752B2 (https=) |
| CA (1) | CA2445835C (https=) |
| CZ (1) | CZ20033194A3 (https=) |
| DE (2) | DE10121217A1 (https=) |
| ES (1) | ES2239226T3 (https=) |
| HU (1) | HUP0304034A2 (https=) |
| SK (1) | SK14482003A3 (https=) |
| WO (1) | WO2002088139A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10121217A1 (de) * | 2001-04-30 | 2002-10-31 | Merck Patent Gmbh | 6H-Oxazolo[4,5-e]indol-Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden |
| AU2003227522A1 (en) * | 2002-05-30 | 2003-12-19 | Neurosearch A/S | 3-substituted quinuclidines and their use |
| WO2005041957A1 (en) * | 2003-10-29 | 2005-05-12 | Pfizer Products Inc. | Oxindole derivatives and their use as phosphodiesterase type 2 inhibitors |
| US9125900B2 (en) * | 2005-09-14 | 2015-09-08 | University Of The Witwatersrand, Johannesburg | Pharmaceutical composition |
| JP6321662B2 (ja) | 2012-10-12 | 2018-05-09 | ザ ブロード インスティテュート, インコーポレーテッドThe Broad Institute, Inc. | Ｇｓｋ３阻害剤およびその使用の方法 |
| SG11201509371XA (en) * | 2013-05-24 | 2015-12-30 | Nestec Sa | Pathway specific markers for diagnosing irritable bowel syndrome |
| US11203601B2 (en) * | 2017-04-05 | 2021-12-21 | The Broad Institute, Inc. | Tricyclic compounds as glycogen synthase kinase 3 (GSK3) inhibitors and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2073340C (en) | 1990-01-11 | 1997-05-20 | Hakan Vilhelm Wikstrom | Centrally acting 6,7,8,9-tetrahydro-3h-benz(e)indole heterocyclics |
| TW263508B (https=) * | 1991-02-12 | 1995-11-21 | Pfizer | |
| EP0773942A1 (en) | 1994-07-26 | 1997-05-21 | Pfizer Inc. | 4-indole derivatives as serotonin agonists and antagonists |
| US6548530B1 (en) * | 1995-10-03 | 2003-04-15 | The Scripps Research Institute | CBI analogs of CC-1065 and the duocarmycins |
| ES2199553T3 (es) | 1998-03-09 | 2004-02-16 | H.Lundbeck A/S | Indoles sustituidos con 5-heteroarilo. |
| DE10045112A1 (de) | 2000-09-11 | 2002-03-21 | Merck Patent Gmbh | Verwendung von Indolderivaten zur Behandlung von Erkrankungen des zentralen Nervensystems |
| DE10121217A1 (de) * | 2001-04-30 | 2002-10-31 | Merck Patent Gmbh | 6H-Oxazolo[4,5-e]indol-Derivate als nikotinische Acetylcholinrezeptor Liganden und/oder serotonerge Liganden |
-
2001
- 2001-04-30 DE DE10121217A patent/DE10121217A1/de not_active Withdrawn
-
2002
- 2002-04-05 CA CA2445835A patent/CA2445835C/en not_active Expired - Fee Related
- 2002-04-05 DE DE60203283T patent/DE60203283T2/de not_active Expired - Lifetime
- 2002-04-05 ES ES02727527T patent/ES2239226T3/es not_active Expired - Lifetime
- 2002-04-05 AT AT02727527T patent/ATE291026T1/de not_active IP Right Cessation
- 2002-04-05 WO PCT/EP2002/003784 patent/WO2002088139A1/en not_active Ceased
- 2002-04-05 US US10/476,306 patent/US7291633B2/en not_active Expired - Fee Related
- 2002-04-05 HU HU0304034A patent/HUP0304034A2/hu unknown
- 2002-04-05 JP JP2002585437A patent/JP4485746B2/ja not_active Expired - Fee Related
- 2002-04-05 SK SK1448-2003A patent/SK14482003A3/sk unknown
- 2002-04-05 CZ CZ20033194A patent/CZ20033194A3/cs unknown
- 2002-04-05 EP EP02727527A patent/EP1392699B1/en not_active Expired - Lifetime
- 2002-04-05 AU AU2002257752A patent/AU2002257752B2/en not_active Ceased
- 2002-04-26 AR ARP020101530A patent/AR033267A1/es not_active Application Discontinuation
-
2007
- 2007-10-30 US US11/928,961 patent/US7741343B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60203283T2 (de) | 2006-03-30 |
| DE10121217A1 (de) | 2002-10-31 |
| ES2239226T3 (es) | 2005-09-16 |
| AR033267A1 (es) | 2003-12-10 |
| ATE291026T1 (de) | 2005-04-15 |
| DE60203283D1 (de) | 2005-04-21 |
| US20050101649A1 (en) | 2005-05-12 |
| JP2004527562A (ja) | 2004-09-09 |
| SK14482003A3 (sk) | 2004-03-02 |
| WO2002088139A1 (en) | 2002-11-07 |
| EP1392699A1 (en) | 2004-03-03 |
| US20080051394A1 (en) | 2008-02-28 |
| AU2002257752B2 (en) | 2008-02-28 |
| CA2445835A1 (en) | 2002-11-07 |
| EP1392699B1 (en) | 2005-03-16 |
| CA2445835C (en) | 2012-01-03 |
| JP4485746B2 (ja) | 2010-06-23 |
| US7741343B2 (en) | 2010-06-22 |
| US7291633B2 (en) | 2007-11-06 |
| CZ20033194A3 (cs) | 2004-02-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |