HUP0303334A2 - Eljárás D-pantoténsav és/vagy sói előállítására állattakarmány-adalékként - Google Patents
Eljárás D-pantoténsav és/vagy sói előállítására állattakarmány-adalékkéntInfo
- Publication number
- HUP0303334A2 HUP0303334A2 HU0303334A HUP0303334A HUP0303334A2 HU P0303334 A2 HUP0303334 A2 HU P0303334A2 HU 0303334 A HU0303334 A HU 0303334A HU P0303334 A HUP0303334 A HU P0303334A HU P0303334 A2 HUP0303334 A2 HU P0303334A2
- Authority
- HU
- Hungary
- Prior art keywords
- salts
- pantothenic acid
- animal feed
- pantothenic
- additive
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 239000000654 additive Substances 0.000 title 1
- 230000000996 additive effect Effects 0.000 title 1
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 abstract 6
- GHOKWGTUZJEAQD-UHFFFAOYSA-N pantothenic acid Chemical compound OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 abstract 4
- 238000000855 fermentation Methods 0.000 abstract 2
- 230000004151 fermentation Effects 0.000 abstract 2
- 229940055726 pantothenic acid Drugs 0.000 abstract 2
- 239000011713 pantothenic acid Substances 0.000 abstract 2
- 235000019161 pantothenic acid Nutrition 0.000 abstract 2
- GHOKWGTUZJEAQD-SSDOTTSWSA-N 3-[[(2s)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]propanoic acid Chemical class OCC(C)(C)[C@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-SSDOTTSWSA-N 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 235000019730 animal feed additive Nutrition 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 230000002074 deregulated effect Effects 0.000 abstract 1
- 239000006052 feed supplement Substances 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 229960000310 isoleucine Drugs 0.000 abstract 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Physiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fodder In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány tárgyát képezi javított eljárás D-pantoténsav és/vagysóinak előállítására olyan mikroorganizmus alkalmazásával, amelyben apantoténsav-(pan) és/vagy izoleucin/vain-(ilv) bioszintézisederegulált, és amely legalább 2 g/l D-pantoténsav-sókat képes termelnifermentációval, 0-20 g/1 (b-alanint, előnyösen (b-alanint nemtartalmazó tenyésztési tápközegben. A fermentlevet anioncserélőreviszik, és a kötődött D-pantotenátot kalcium- és/vagy magnézium-D-pantotenát formájában, vagy hidrogénklorid-oldattal eluálják szabad D-pantoténsav formájában, és az eluátumot vagy oldatot szárítják és/vagyformázzák. A végterméket állattakarmány-adalékként és/vagykiegészítőként lehet alkalmazni. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10108222 | 2001-02-21 | ||
| PCT/EP2002/001755 WO2002066665A2 (de) | 2001-02-21 | 2002-02-20 | Verfahren zur herstellung von d-pantothensäure und/oder deren salze als zusatz zu tierfuttermitteln |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0303334A2 true HUP0303334A2 (hu) | 2004-01-28 |
| HUP0303334A3 HUP0303334A3 (en) | 2007-09-28 |
Family
ID=7674920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0303334A HUP0303334A3 (en) | 2001-02-21 | 2002-02-20 | Method for producing d-pantothenic caid and/or salts thereof as an additive for animal feed |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7727748B2 (hu) |
| EP (1) | EP1362116B1 (hu) |
| JP (1) | JP2004523237A (hu) |
| KR (1) | KR20030075206A (hu) |
| CN (1) | CN100457917C (hu) |
| AT (1) | ATE349544T1 (hu) |
| AU (1) | AU2002246094A1 (hu) |
| BR (1) | BR0207473A (hu) |
| CA (1) | CA2438948A1 (hu) |
| CZ (1) | CZ20032244A3 (hu) |
| DE (1) | DE50209076D1 (hu) |
| EE (1) | EE200300405A (hu) |
| ES (1) | ES2278906T3 (hu) |
| HU (1) | HUP0303334A3 (hu) |
| IL (1) | IL157402A0 (hu) |
| IN (1) | IN2003CH01297A (hu) |
| MX (1) | MXPA03007456A (hu) |
| NO (1) | NO20033706L (hu) |
| PL (1) | PL363917A1 (hu) |
| RU (1) | RU2003128532A (hu) |
| SK (1) | SK10422003A3 (hu) |
| WO (1) | WO2002066665A2 (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10344200A1 (de) * | 2003-09-22 | 2005-05-04 | Basf Ag | Verfahren zur Herstellung eines D-Pantothensäure und/oder deren Salze enthaltendes Tierfuttersupplement |
| CN1946851B (zh) * | 2004-04-26 | 2012-04-18 | 帝斯曼知识产权资产管理有限公司 | 用于制备d-泛酸钙的方法 |
| EP2723878B1 (en) | 2011-06-21 | 2020-05-20 | DSM IP Assets B.V. | Vitamin b5 production |
| WO2012175574A1 (en) | 2011-06-21 | 2012-12-27 | Dsm Ip Assets B.V. | Increased pantothenate (vitamin b5) production |
| US11293039B2 (en) | 2017-10-02 | 2022-04-05 | Metabolic Explorer | Method for producing organic acid salts from fermentation broth |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB562267A (en) | 1941-08-08 | 1944-06-26 | Hoffmann La Roche | Process for the manufacture of a crystallised, non-hygroscopic calcium salt of d-pantothenic acid |
| EP0493060A3 (en) | 1990-12-25 | 1993-04-14 | Takeda Chemical Industries, Ltd. | Production method of d-pantothenic acid and plasmids and microorganisms thereof |
| JP3710497B2 (ja) | 1992-09-25 | 2005-10-26 | ビーエーエスエフ アクチェンゲゼルシャフト | Ｄ−パント酸、ｄ−パントテン酸およびそれらの塩の製造法 |
| AU6943696A (en) | 1995-09-13 | 1997-04-01 | Takeda Chemical Industries Ltd. | Process for producing d-pantoic acid and d-pantothenic acid or salts thereof |
| JP2002508921A (ja) | 1997-10-04 | 2002-03-26 | フォルシュングスツェントルム・ユーリッヒ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | アスパラギン酸−及び（又は）グルタミン酸系アミノ酸の微生物による産生方法及びこの方法で使用可能な剤 |
| AT407050B (de) | 1997-12-29 | 2000-11-27 | Chemie Linz Gmbh | Verfahren zur herstellung von l-asparaginsäure |
| DE19846499A1 (de) | 1998-10-09 | 2000-04-20 | Degussa | Verfahren zur Herstellung von Pantothensäure durch Verstärkung von für Ketopantoat-Reduktase kodierenden Nukleotidsequenzen |
| DE19855313A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentativen Herstellung von D-Pantothensäure durch Verstärkung des panD-Gens in Mikroorganismen |
| PT1050219E (pt) | 1999-05-05 | 2003-04-30 | Degussa | Aditivos alimentares para animais contendo acido d-pantotenico e/ou seus sais e processo para a sua preparacao |
| US8232081B2 (en) * | 1999-09-21 | 2012-07-31 | Basf Se | Methods and microorganisms for production of panto-compounds |
| MXPA02003017A (es) * | 1999-09-21 | 2004-09-06 | Basf Ag | Metodos y microorganismos para la produccion de panto-compuestos. |
| DE10021515A1 (de) * | 2000-05-03 | 2001-11-08 | Degussa | Verfahren zur Herstellung von Erdalkalisalzen der D-Pantothensäure |
| IL154824A0 (en) * | 2000-09-20 | 2003-10-31 | Basf Ag | Animal feed supplement containing d-pantothenic acid and/or its salts, improved method for the production thereof, and its use |
-
2002
- 2002-02-20 RU RU2003128532/13A patent/RU2003128532A/ru not_active Application Discontinuation
- 2002-02-20 IL IL15740202A patent/IL157402A0/xx unknown
- 2002-02-20 BR BR0207473-7A patent/BR0207473A/pt not_active IP Right Cessation
- 2002-02-20 AT AT02714168T patent/ATE349544T1/de not_active IP Right Cessation
- 2002-02-20 AU AU2002246094A patent/AU2002246094A1/en not_active Abandoned
- 2002-02-20 KR KR20037010983A patent/KR20030075206A/ko not_active Application Discontinuation
- 2002-02-20 US US10/468,562 patent/US7727748B2/en not_active Expired - Fee Related
- 2002-02-20 MX MXPA03007456A patent/MXPA03007456A/es unknown
- 2002-02-20 EE EEP200300405A patent/EE200300405A/xx unknown
- 2002-02-20 SK SK1042-2003A patent/SK10422003A3/sk unknown
- 2002-02-20 DE DE50209076T patent/DE50209076D1/de not_active Expired - Lifetime
- 2002-02-20 ES ES02714168T patent/ES2278906T3/es not_active Expired - Lifetime
- 2002-02-20 EP EP02714168A patent/EP1362116B1/de not_active Expired - Lifetime
- 2002-02-20 PL PL02363917A patent/PL363917A1/xx not_active Application Discontinuation
- 2002-02-20 HU HU0303334A patent/HUP0303334A3/hu unknown
- 2002-02-20 CZ CZ20032244A patent/CZ20032244A3/cs unknown
- 2002-02-20 CN CNB02805329XA patent/CN100457917C/zh not_active Expired - Fee Related
- 2002-02-20 CA CA002438948A patent/CA2438948A1/en not_active Abandoned
- 2002-02-20 WO PCT/EP2002/001755 patent/WO2002066665A2/de active IP Right Grant
- 2002-02-20 JP JP2002566369A patent/JP2004523237A/ja active Pending
-
2003
- 2003-08-19 IN IN1297CH2003 patent/IN2003CH01297A/xx unknown
- 2003-08-20 NO NO20033706A patent/NO20033706L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL363917A1 (en) | 2004-11-29 |
| EP1362116A2 (de) | 2003-11-19 |
| EP1362116B1 (de) | 2006-12-27 |
| CN100457917C (zh) | 2009-02-04 |
| EE200300405A (et) | 2003-12-15 |
| AU2002246094A1 (en) | 2002-09-04 |
| NO20033706L (no) | 2003-10-14 |
| JP2004523237A (ja) | 2004-08-05 |
| MXPA03007456A (es) | 2004-07-30 |
| HUP0303334A3 (en) | 2007-09-28 |
| KR20030075206A (ko) | 2003-09-22 |
| BR0207473A (pt) | 2004-04-06 |
| CA2438948A1 (en) | 2002-08-29 |
| NO20033706D0 (no) | 2003-08-20 |
| IN2003CH01297A (en) | 2005-11-25 |
| ATE349544T1 (de) | 2007-01-15 |
| WO2002066665A3 (de) | 2003-07-17 |
| DE50209076D1 (de) | 2007-02-08 |
| US20040077057A1 (en) | 2004-04-22 |
| WO2002066665A2 (de) | 2002-08-29 |
| SK10422003A3 (sk) | 2004-02-03 |
| US7727748B2 (en) | 2010-06-01 |
| CN1496406A (zh) | 2004-05-12 |
| ES2278906T3 (es) | 2007-08-16 |
| IL157402A0 (en) | 2004-03-28 |
| CZ20032244A3 (cs) | 2003-11-12 |
| RU2003128532A (ru) | 2005-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |