HUP0303197A2 - Alfa-2-adrenerg agonista komponenseket tartalmazó készítmények - Google Patents

Alfa-2-adrenerg agonista komponenseket tartalmazó készítmények

Info

Publication number
HUP0303197A2
HUP0303197A2 HU0303197A HUP0303197A HUP0303197A2 HU P0303197 A2 HUP0303197 A2 HU P0303197A2 HU 0303197 A HU0303197 A HU 0303197A HU P0303197 A HUP0303197 A HU P0303197A HU P0303197 A2 HUP0303197 A2 HU P0303197A2
Authority
HU
Hungary
Prior art keywords
adrenergic agonist
component
compositions containing
solubility
containing alpha
Prior art date
Application number
HU0303197A
Other languages
English (en)
Inventor
Edward D.S. Kerslake
Orest Olejnik
Original Assignee
Allergan, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22814143&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0303197(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan, Inc. filed Critical Allergan, Inc.
Publication of HUP0303197A2 publication Critical patent/HUP0303197A2/hu
Publication of HUP0303197A3 publication Critical patent/HUP0303197A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734—Alginic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

A találmány szerinti készítmények a következő komponensekettartalmazzák: - a-2-adrenerg agonista komponens a készítménnyelkezelendő betegen a kívánt terápiás hatás elérésére atkalmasmennyiségben, - oldékonyságfokozó komponens a készítményben lévő a-2-adrenerg agonista komponens oldékonyságának az oldékonyságfokozókomponenst nem tartalmazó, egyébként hasonló összetételű készítménybenészlelhetőhöz képesti megnövelésére alkalmas mennyiségben, és -folyékony hordozó komponens. Ó
HU0303197A 2000-07-14 2001-07-09 Compositions containing alpha-2 adrenergic agonist components HUP0303197A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21820000P 2000-07-14 2000-07-14
PCT/US2001/021552 WO2002005853A2 (en) 2000-07-14 2001-07-09 Compositions containing alpha-2-adrenergic agonist components

Publications (2)

Publication Number Publication Date
HUP0303197A2 true HUP0303197A2 (hu) 2003-12-29
HUP0303197A3 HUP0303197A3 (en) 2008-03-28

Family

ID=22814143

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303197A HUP0303197A3 (en) 2000-07-14 2001-07-09 Compositions containing alpha-2 adrenergic agonist components

Country Status (20)

Country Link
US (4) US6627210B2 (hu)
EP (1) EP1365811A2 (hu)
JP (3) JP4927298B2 (hu)
KR (1) KR100757656B1 (hu)
CN (2) CN101897704B (hu)
AR (1) AR033539A1 (hu)
AU (2) AU7326901A (hu)
BR (1) BR0109317A (hu)
CA (1) CA2402405C (hu)
HK (1) HK1060519A1 (hu)
HU (1) HUP0303197A3 (hu)
IL (2) IL151530A0 (hu)
MX (1) MXPA02008930A (hu)
NO (1) NO333367B1 (hu)
NZ (1) NZ521185A (hu)
PL (1) PL360707A1 (hu)
RU (1) RU2311928C2 (hu)
TW (1) TWI287998B (hu)
WO (1) WO2002005853A2 (hu)
ZA (1) ZA200207413B (hu)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011250793B2 (en) * 2000-07-14 2012-11-29 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
US20040214829A1 (en) * 2000-07-14 2004-10-28 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
US8858961B2 (en) 2000-07-14 2014-10-14 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
JP2004503593A (ja) * 2000-07-14 2004-02-05 アラーガン、インコーポレイテッド 増大した溶解度を持つ治療活性成分を含む組成物
EP1365811A2 (en) * 2000-07-14 2003-12-03 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
US20050026924A1 (en) * 2000-07-14 2005-02-03 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
AU2002256471B2 (en) * 2001-05-03 2007-05-24 Allergan, Inc. Compositions having enhanced pharmacokinetic characteristics
US20020198209A1 (en) 2001-05-03 2002-12-26 Allergan Sales Inc. Compositions having enhanced pharmacokinetic characteristics
US6753017B2 (en) * 2001-11-07 2004-06-22 Jrs Pharma Lp Process for preparing dry extracts
US7642258B2 (en) * 2002-04-19 2010-01-05 Allergan, Inc. Combination of brimonidine and timolol for topical ophthalmic use
US7030149B2 (en) 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
US6982079B2 (en) * 2002-04-26 2006-01-03 Allergan, Inc. Compositions for treating hyperemia
US20040266776A1 (en) * 2003-06-25 2004-12-30 Gil Daniel W. Methods of preventing and reducing the severity of stress-associated conditions
EP1549305B1 (en) * 2002-10-08 2009-04-22 Allergan, Inc. Alpha 2b 0r 2b/2c adrenoceptor agonists for the treatment of morbus alzheimer and morbus parkinson
CN100370988C (zh) * 2002-10-08 2008-02-27 阿勒根公司 (2-咪唑啉-2-基氨基)喹噁啉在制备治疗痴呆症和帕金森病的药物中的用途
US20040137079A1 (en) * 2003-01-08 2004-07-15 Cook James N. Contact lens and eye drop rewetter compositions and methods
US20040191332A1 (en) * 2003-03-27 2004-09-30 Allergan, Inc. Preserved ophthalmic compositions
US7439241B2 (en) 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
WO2005014046A2 (en) * 2003-08-07 2005-02-17 Allergan, Inc. Compositions for delivery of therapeutics into the eyes and methods for making and using the same
CA2543458A1 (en) * 2003-10-24 2005-05-12 Josef Rettenmaier & Soehne Gmbh & Co., Kg Process for co-spray drying agents with dry silicified mcc
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US20050244469A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Extended therapeutic effect ocular implant treatments
US8529927B2 (en) * 2004-04-30 2013-09-10 Allergan, Inc. Alpha-2 agonist polymeric drug delivery systems
US8673341B2 (en) * 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US20050244463A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US8425929B2 (en) * 2004-04-30 2013-04-23 Allergan, Inc. Sustained release intraocular implants and methods for preventing retinal dysfunction
CA2505836C (en) * 2004-05-06 2013-08-27 Alcon Inc. Topical brimonidine tartrate formulations that lack chlorine dioxide
BRPI0511519A (pt) * 2004-05-25 2007-12-26 Sansrosa Pharmaceutical Dev In método para tratar ou prevenir um distúrbio inflamatório da pele e os sintomas associados com ele, composição tópica adequada para tratar ou evitar os sintomas de um distúrbio inflamatório dermatológico, e, embalagem para uma composição tópica
JP4789454B2 (ja) * 2004-12-03 2011-10-12 株式会社キーエンス 蛍光顕微鏡
US20060228487A1 (en) * 2005-04-11 2006-10-12 J. Rettenmaier & Söehne GmbH + Co. KG Methods of combining active agents with augmented microcrystalline cellulose
DE602006016303D1 (de) * 2005-08-25 2010-09-30 Pharmacopeia Llc 3,4-dihydro-2H-benzoÄ1,4Üoxazin- und 3,4-dihydro-2H-benzoÄ1,4Üthiazin-VERBINDUNGEN ALS ALPHA2C-ADRENOREZEPTOR-ANTAGONISTEN
US7803828B2 (en) * 2005-08-25 2010-09-28 Schering-Plough Corporation Functionally selective alpha2C adrenoreceptor agonists
US7700592B2 (en) * 2005-08-25 2010-04-20 Schering Corporation α2C adrenoreceptor agonists
US8003624B2 (en) * 2005-08-25 2011-08-23 Schering Corporation Functionally selective ALPHA2C adrenoreceptor agonists
JP2009514969A (ja) 2005-11-09 2009-04-09 コンビナトアールエックス インコーポレーティッド 医学的状態を治療するための方法、組成物、およびキット
US20070238732A1 (en) * 2006-04-10 2007-10-11 Allergan, Inc. Brimonidine and timolol compositions
US8969415B2 (en) * 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
BRPI0905715A2 (pt) * 2008-02-15 2015-07-14 Bone Therapeutics Composição farmacêutica e kit de componentes
EP2252290B1 (en) * 2008-02-15 2017-11-29 Bone Therapeutics S.A. Pharmaceutical composition for use in the treatment and/or the prevention of osteoarticular diseases
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
US7842714B2 (en) * 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
US20110003823A1 (en) * 2008-08-01 2011-01-06 Alpha Synergy Development, Inc. Compositions and methods for treatment of diseases and conditions associated with vasodilation and/or vascular leakage
US20100202979A1 (en) * 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of pulmonary diseases and conditions
US20100197694A1 (en) * 2008-08-01 2010-08-05 Gerald Horn Compositions and methods for treatment of diseases and conditions with increased vascular permeability
US20120156244A1 (en) * 2008-08-01 2012-06-21 Alpha Synergy Development Inc. Nasal Compositions and Uses Thereof
SI2320911T1 (sl) * 2008-08-01 2014-12-31 Eye Therapies Llc Vazokonstrikcijski sestavki in metode uporabe
US8952011B2 (en) 2008-08-01 2015-02-10 Eye Therapies Llc Compositions and methods for the treatment of nasal conditions
US20100203165A1 (en) 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of disorders or conditions of the eye
US20110190247A1 (en) * 2008-08-04 2011-08-04 Schering Corporation Cyclopropylchromene derivatives as modulators of the alpha-2c receptor
TW201026691A (en) 2008-10-07 2010-07-16 Schering Corp Biaryl spiroaminooxazoline analogues as alpha2C adrenergic receptor modulators
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
US8987270B2 (en) 2009-07-27 2015-03-24 Eye Therapies Llc Formulations of selective alpha-2 agonists and methods of use thereof
BR122017013201B1 (pt) 2009-11-09 2018-05-15 Allergan, Inc. Composição para a estimulação de crescimento capilar
US20110152271A1 (en) * 2009-12-17 2011-06-23 Gerald Horn Compositions and methods for ophthalmic delivery of nasal decongestants
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
KR102126007B1 (ko) 2010-01-22 2020-06-24 알러간, 인코포레이티드 전방내 서방성 치료제 이식물
MX2012010824A (es) 2010-03-26 2012-10-10 Galderma Res & Dev Metodos y composiciones mejoradas para tratamiento seguro y efectivo del eritema.
US8445526B2 (en) 2011-02-03 2013-05-21 Glaucoma & Nasal Therapies Llc Compositions and methods for treatment of glaucoma
US9744168B2 (en) 2011-10-19 2017-08-29 Galderma Laboratories, Inc. Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors
CN109602691A (zh) 2013-02-15 2019-04-12 阿勒根公司 持续药物递送植入物
US8999938B2 (en) 2013-06-21 2015-04-07 Gnt Llc Ophthalmic lipophilic drug delivery vehicle formulations
DK3062775T3 (en) 2013-10-31 2018-03-12 Allergan Inc PROSTAMID-CONTAINING INTRAOCULAR IMPLANTS AND PROCEDURES FOR USE THEREOF
US10517869B2 (en) 2013-12-24 2019-12-31 Sentiss Pharma Private Limited Topical brimonidine tartrate ophthalmic solution
US20180078500A1 (en) * 2015-03-19 2018-03-22 Allergan, Inc. Fixed dose combination of brimonidine and timolol
KR102275012B1 (ko) 2016-08-12 2021-07-07 실크 테크놀로지스 리미티드 염증 치료용 실크 유래 단백질
JP2022531116A (ja) 2019-05-01 2022-07-06 クレキシオ バイオサイエンシーズ エルティーディー． そう痒症を治療する方法
KR20240045074A (ko) 2022-09-29 2024-04-05 주식회사태준제약 브리모니딘을 포함하는 안과용 조성물

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL286080A (hu) * 1961-11-30
US3278447A (en) 1963-12-02 1966-10-11 Cloro Bac Products Inc Process for stabilizing chlorine dioxide solution
BE795970A (fr) 1972-02-29 1973-08-27 Pfizer Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant
US4530920A (en) 1983-11-07 1985-07-23 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonist
US4806556A (en) 1985-12-12 1989-02-21 Regents Of The University Of Minnesota Gut-selective opiates
US5719197A (en) 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5607698A (en) 1988-08-04 1997-03-04 Ciba-Geigy Corporation Method of preserving ophthalmic solution and compositions therefor
US5202128A (en) 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
CA2007181C (en) 1989-01-06 1998-11-24 Angelo Mario Morella Sustained release pharmaceutical composition
JPH085779B2 (ja) * 1989-09-22 1996-01-24 杏林製薬株式会社 フレロキサシン点眼液
US5352796A (en) 1989-10-30 1994-10-04 The Salk Institute For Biological Studies Amino acids useful in making GnRH analogs
US5021416A (en) 1989-10-31 1991-06-04 Allergan, Inc. Method for using (2-imidazolin-2-ylamino) quinoxalines to reduce or maintain intraocular pressure
US5215991A (en) * 1990-01-26 1993-06-01 Allergan, Inc. Combination of selective alpha-adrenergic agonists and Na+ /H+ ex
GB9017353D0 (en) 1990-08-08 1990-09-19 Merck Sharp & Dohme Chemical process
IT1252692B (it) * 1991-11-27 1995-06-23 Zambon Spa Composizione farmaceutica per uso oftalmico contenente un antiinfiammatorio non steroideo ed un decongestionante come principi attivi
JPH05271053A (ja) * 1992-03-27 1993-10-19 Lion Corp 安定な点眼剤
US5459133A (en) * 1992-06-05 1995-10-17 Telor Ophthalmic Pharmaceuticals, Inc. Methods and products for treating presbyopia
WO1994016685A1 (en) 1993-01-28 1994-08-04 University Of Iowa Research Foundation Ophthalmic uses of signa agonists
JP3683908B2 (ja) 1993-10-13 2005-08-17 アラーガン、インコーポレイテッド （２−イミダゾリン−２−イルアミノ）キノキサリン誘導体の使用方法
US5994110A (en) 1995-02-10 1999-11-30 Mosbach; Klaus Methods for direct synthesis of compounds having complementary structure to a desired molecular entity and use thereof
US6294563B1 (en) * 1994-10-27 2001-09-25 Allergan Sales, Inc. Combinations of prostaglandins and brimonidine or derivatives thereof
US5856329A (en) * 1995-06-28 1999-01-05 Allergan Method of using (2-imidazolin-2-ylamino) quinoxalines in treating ocular neural injury
ZA965837B (en) 1995-07-11 1997-01-31 Merck & Co Inc A triazolylmethyl-indole ethylamine bisulfate salt
EP0834308A1 (en) 1996-09-30 1998-04-08 LG Chemical Limited Ophthalmic formulation for treating myopia comprising dopamine agonist and cyclodextrin
WO1998047878A1 (en) 1997-04-18 1998-10-29 Abbott Laboratories A process for the preparation of highly pure 6,7-dichloro-5- nitro-2,3-dihydroquinoxaline-2,3-dione
MY116782A (en) * 1997-12-22 2004-03-31 Otsuka Pharma Co Ltd Water-soluble eye drop
AU2870899A (en) 1998-02-26 1999-09-15 Abbott Laboratories Oral formulation for hydrophilic drugs
TR200002848T2 (tr) 1998-04-07 2001-02-21 Alcon Laboratories, Inc. Ksantan zamkı içeren, jelleşen oftalmik bileşimler.
AU757896B2 (en) * 1998-09-02 2003-03-13 Allergan, Inc. Preserved cyclodextrin-containing compositions
WO2000019981A1 (en) 1998-10-08 2000-04-13 Karagoezian Hampar L Synergistic antimicrobial, dermatological and ophthalmic preparations containing chlorite and hydrogen peroxide
IN185228B (hu) * 1999-02-03 2000-12-09 Bakulesh Mafatlal Dr Khamar
JP2004503593A (ja) * 2000-07-14 2004-02-05 アラーガン、インコーポレイテッド 増大した溶解度を持つ治療活性成分を含む組成物
EP1365811A2 (en) * 2000-07-14 2003-12-03 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components

Also Published As

Publication number Publication date
NO20024221L (no) 2002-10-28
CA2402405C (en) 2008-02-12
PL360707A1 (en) 2004-09-20
NO20024221D0 (no) 2002-09-04
US20040063689A1 (en) 2004-04-01
CN101897704B (zh) 2014-10-29
TWI287998B (en) 2007-10-11
CN101897704A (zh) 2010-12-01
BR0109317A (pt) 2003-06-17
US20020032201A1 (en) 2002-03-14
CN1460026A (zh) 2003-12-03
JP2008231122A (ja) 2008-10-02
JP4927298B2 (ja) 2012-05-09
ZA200207413B (en) 2004-04-08
KR20030017500A (ko) 2003-03-03
JP2004504279A (ja) 2004-02-12
IL151530A (en) 2009-05-04
AR033539A1 (es) 2003-12-26
NO333367B1 (no) 2013-05-13
US20030027811A1 (en) 2003-02-06
US6673337B2 (en) 2004-01-06
HK1060519A1 (en) 2004-08-13
KR100757656B1 (ko) 2007-09-10
JP2012067128A (ja) 2012-04-05
AU2001273269B2 (en) 2005-08-11
MXPA02008930A (es) 2003-03-31
CN100569291C (zh) 2009-12-16
AU7326901A (en) 2002-01-30
US6627210B2 (en) 2003-09-30
HUP0303197A3 (en) 2008-03-28
WO2002005853A2 (en) 2002-01-24
EP1365811A2 (en) 2003-12-03
WO2002005853A3 (en) 2003-09-12
IL151530A0 (en) 2003-04-10
US20030087893A1 (en) 2003-05-08
RU2311928C2 (ru) 2007-12-10
NZ521185A (en) 2005-02-25
US6641834B2 (en) 2003-11-04
CA2402405A1 (en) 2002-01-24

Similar Documents

Publication Publication Date Title
HUP0303197A2 (hu) Alfa-2-adrenerg agonista komponenseket tartalmazó készítmények
HUP0301405A2 (hu) Fokozott oldékonyságú gyógyhatású komponenseket tartalmazó készítmények
HK1036970A1 (en) Compounds and compositions for delivering active agents.
UA88463C2 (ru) Фармацевтическая композиция, которая содержит соединение 1, и процесс лечения вич-инфекции
HK1054918A1 (en) Compounds and compositions for delivering active agents
ATE383169T1 (de) Komponente und zusammensetzungen zur verabreichung von wirkstoffen
MXPA03007837A (es) Composiciones para suministrar bisfosfonatos.
HK1112182A1 (en) Skin lightening compositions
HK1036969A1 (en) Compounds and compositions for delivering active agents
TW200505411A (en) A formulation for chemical peeling
TW200605870A (en) Topical methadone compositions and methods for using the same
MX2007003078A (es) Compuestos de imidazoquinolina.
MY143795A (en) Tetrahydropyridoindole derivatives
MY137202A (en) System and method for a unified composition engine in a graphics processing system
EA200501268A1 (ru) Ингибирующие вич 1,2,4-триазины
GEP20053568B (en) NMDA Receptor Agonist Pharmaceutical Compositions
WO2004091540A3 (en) Methods of treating pain and compositions for use therefor
ATE311373T1 (de) Oxadiazolverbindungen und -zusammensetzungen zur abgabe von wirkstoffen
EA200701172A1 (ru) 2-алкокси-3,4,5-тригидроксиалкиламиды, их получение, композиции, их содержащие, и применение
YU13301A (sh) Muskarinski agonisti i antagonisti
AU9551201A (en) Combination of a transdermal therapeutic system and an oral and/or parenteral preparation containing dopamine agonists for the treatment of dopaminergic diseasestates
MXPA04001256A (es) Productos de combinacion de derivados de propanolamina aril substituidos con otros ingredientes activos y su uso.
EE05124B1 (et) Toimeainena dotsetakseeli v?i selle hdraati sisaldava kompositsiooni kasutamine
HK1111924A1 (en) Depigmenting or brightening cosmetic composition comprising at least one oxazolin as an active ingredient
PL351376A1 (en) Endoparasiticidal synergistic combination containing cyclic depsipeptides and piperazines

Legal Events

Date Code Title Description
FC4A Lapse of provisional application due to refusal