HUP0302798A2 - Javított eljárások pantotenát előállítására - Google Patents

Javított eljárások pantotenát előállítására

Info

Publication number
HUP0302798A2
HUP0302798A2 HU0302798A HUP0302798A HUP0302798A2 HU P0302798 A2 HUP0302798 A2 HU P0302798A2 HU 0302798 A HU0302798 A HU 0302798A HU P0302798 A HUP0302798 A HU P0302798A HU P0302798 A2 HUP0302798 A2 HU P0302798A2
Authority
HU
Hungary
Prior art keywords
pantothenate
processes
microorganisms
enhanced production
production
Prior art date
Application number
HU0302798A
Other languages
English (en)
Inventor
Kai-Uwe Baldenius
Christine Beck
Theron Hermann
Thomas Patterson
Janice G. Pero
Roger R. Yocum
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of HUP0302798A2 publication Critical patent/HUP0302798A2/hu
Publication of HUP0302798A3 publication Critical patent/HUP0302798A3/hu
Publication of HU230549B1 publication Critical patent/HU230549B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Abstract

A találmány tárgyát javított eljárások képezik pantoát és pantotenátelőállítására olyan milroorganizmusok felhasználásával, amelyekmódosított pantotenát bioszintetikus enzimaktivitásokkal rendelkeznek.A találmány főleg melléktermék képződést csökkentő és a hozamot és akívánt termék tisztaságát növelő eljárásokat nyújt. Rekombinánsmikroorganizmusok és ezek tenyésztésére alkalmas körülmények, valamintaz ilyen mikroorganizmusok által előállított készítmények szintén atalálmány oltalmi körébe tartoznak. Ó
HU0302798A 2001-01-19 2002-01-19 Javított eljárások pantotenát előállítására HU230549B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26299501P 2001-01-19 2001-01-19
US60/262,995 2001-01-19
PCT/US2002/001842 WO2002057474A2 (en) 2001-01-19 2002-01-19 Processes for enhanced production of pantothenate

Publications (3)

Publication Number Publication Date
HUP0302798A2 true HUP0302798A2 (hu) 2003-11-28
HUP0302798A3 HUP0302798A3 (en) 2011-05-30
HU230549B1 HU230549B1 (hu) 2016-11-28

Family

ID=22999939

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0302798A HU230549B1 (hu) 2001-01-19 2002-01-19 Javított eljárások pantotenát előállítására

Country Status (18)

Country Link
US (1) US7220561B2 (hu)
EP (1) EP1370670A2 (hu)
JP (1) JP4217070B2 (hu)
KR (1) KR20040004496A (hu)
CN (1) CN100543143C (hu)
AU (1) AU2002247012A1 (hu)
BR (1) BR0206587A (hu)
CA (1) CA2434483A1 (hu)
CZ (1) CZ20031978A3 (hu)
EE (1) EE200300343A (hu)
HU (1) HU230549B1 (hu)
IL (1) IL156613A0 (hu)
MX (1) MXPA03006342A (hu)
NO (1) NO20033267L (hu)
PL (1) PL373006A1 (hu)
RU (1) RU2003125653A (hu)
SK (1) SK9022003A3 (hu)
WO (1) WO2002057474A2 (hu)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8232081B2 (en) * 1999-09-21 2012-07-31 Basf Se Methods and microorganisms for production of panto-compounds
HU227432B1 (hu) * 2001-01-19 2011-06-28 Basf Ag Mikroorganizmusok és eljárások pantotenát fokozott termelésére
KR20040004495A (ko) * 2001-01-19 2004-01-13 바스프 악티엔게젤샤프트 3-(2-히드록시-3-메틸-부티릴아미노)-프로피온산(ｈｍｂｐａ)의 제조 방법 및 이를 위한 미생물
DE10108223A1 (de) 2001-02-21 2002-10-10 Basf Ag Verfahren zur Herstellung von D-Pantothensäure und/oder deren Salze als Zusatz zu Tierfuttermitteln
US7989187B2 (en) 2002-07-03 2011-08-02 Basf Se Microorganisms and processes for enhanced production of pantothenate
CN100455669C (zh) * 2002-07-03 2009-01-28 巴斯福股份公司 用于提高泛酸产量的微生物和方法
CN1809631B (zh) * 2003-06-18 2010-05-26 帝斯曼知识产权资产管理有限公司 用不能形成芽孢的微生物来生产泛酸盐/酯的方法
DE10344200A1 (de) * 2003-09-22 2005-05-04 Basf Ag Verfahren zur Herstellung eines D-Pantothensäure und/oder deren Salze enthaltendes Tierfuttersupplement
WO2007131750A1 (en) 2006-05-16 2007-11-22 Dsm Ip Assets B.V. Process for the production of panthenol
EP2157174A1 (en) 2008-08-12 2010-02-24 DSM IP Assets B.V. Increased production of pantothenate (vitamin B5)
EP2550365B1 (en) 2010-03-22 2018-07-04 Stemina Biomarker Discovery, Inc. Predicting human developmental toxicity of pharmaceuticals using human stem-like cells and metabolomics
WO2011156794A2 (en) * 2010-06-11 2011-12-15 The Regents Of The University Of California Synthetic pathways for biofuel synthesis
WO2012175574A1 (en) 2011-06-21 2012-12-27 Dsm Ip Assets B.V. Increased pantothenate (vitamin b5) production
WO2012175575A2 (en) 2011-06-21 2012-12-27 Dsm Ip Assets B.V. Increased vitamin b5 production
ES2908342T3 (es) 2013-07-23 2022-04-28 Ptt Global Chemical Public Co Ltd Método de producción de ácido succínico utilizando difusión facilitada para la importación de azúcar
CN103980150B (zh) * 2014-04-12 2016-08-17 烟台恒迪克能源科技有限公司 一种脂肪醇醚烷酰基氨基酸钠的合成方法
CN109868254B (zh) * 2019-03-14 2021-02-19 浙江工业大学 一种高产泛酸的基因工程菌、构建方法及应用
US20240002817A1 (en) * 2020-10-02 2024-01-04 Codexis, Inc. Engineered pantothenate kinase variant enzymes
EP4323331A1 (en) 2021-04-15 2024-02-21 DSM IP Assets B.V. Production of panthenol
EP4108654A1 (en) 2021-06-23 2022-12-28 DSM IP Assets B.V. Production of panthenol

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3710497B2 (ja) * 1992-09-25 2005-10-26 ビーエーエスエフ アクチェンゲゼルシャフト Ｄ−パント酸、ｄ−パントテン酸およびそれらの塩の製造法
DE19846499A1 (de) * 1998-10-09 2000-04-20 Degussa Verfahren zur Herstellung von Pantothensäure durch Verstärkung von für Ketopantoat-Reduktase kodierenden Nukleotidsequenzen
DE19855312A1 (de) 1998-12-01 2000-06-08 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien
DE19855314A1 (de) * 1998-12-01 2000-06-08 Degussa Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae
HU230509B1 (hu) * 1999-09-21 2016-09-28 Basf Aktiengesellschaft Eljárások és mikroorganizmusok panto-vegyületek előállítására
JP2001089706A (ja) 1999-09-21 2001-04-03 Toto Ltd 光触媒性親水性コート剤
HU227432B1 (hu) * 2001-01-19 2011-06-28 Basf Ag Mikroorganizmusok és eljárások pantotenát fokozott termelésére
DE10106460A1 (de) * 2001-02-13 2002-08-14 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen

Also Published As

Publication number Publication date
JP4217070B2 (ja) 2009-01-28
US20040086982A1 (en) 2004-05-06
CN1496405A (zh) 2004-05-12
MXPA03006342A (es) 2004-12-03
EP1370670A2 (en) 2003-12-17
NO20033267L (no) 2003-09-19
WO2002057474A2 (en) 2002-07-25
AU2002247012A1 (en) 2002-07-30
CA2434483A1 (en) 2002-07-25
WO2002057474A3 (en) 2003-10-02
HU230549B1 (hu) 2016-11-28
SK9022003A3 (en) 2003-12-02
US7220561B2 (en) 2007-05-22
BR0206587A (pt) 2005-12-13
NO20033267D0 (no) 2003-07-18
CZ20031978A3 (en) 2004-06-16
EE200300343A (et) 2003-10-15
HUP0302798A3 (en) 2011-05-30
JP2005501509A (ja) 2005-01-20
KR20040004496A (ko) 2004-01-13
RU2003125653A (ru) 2005-03-10
PL373006A1 (en) 2005-08-08
CN100543143C (zh) 2009-09-23
IL156613A0 (en) 2004-01-04

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Legal Events

Date Code Title Description
FH91 Appointment of a representative

Free format text: FORMER REPRESENTATIVE(S): BELICZAY LASZLO, S.B.G. & K. SZABADALMI UEGYVIVOEI IRODA, HU

Representative=s name: S.B.G & K. SZABADALMI UEGYVIVOEI IRODA, HU

FH92 Termination of representative

Representative=s name: BELICZAY LASZLO, S.B.G. & K. SZABADALMI UEGYVI, HU

MM4A Lapse of definitive patent protection due to non-payment of fees