HUP0204270A2 - Eljárás ciklohexánkarbonitril-származékok és intermedierjeik előállítására - Google Patents
Eljárás ciklohexánkarbonitril-származékok és intermedierjeik előállításáraInfo
- Publication number
- HUP0204270A2 HUP0204270A2 HU0204270A HUP0204270A HUP0204270A2 HU P0204270 A2 HUP0204270 A2 HU P0204270A2 HU 0204270 A HU0204270 A HU 0204270A HU P0204270 A HUP0204270 A HU P0204270A HU P0204270 A2 HUP0204270 A2 HU P0204270A2
- Authority
- HU
- Hungary
- Prior art keywords
- intermediates
- cyclohexancarbonitrile
- derivatives
- preparing
- compounds
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title abstract 2
- VBWIZSYFQSOUFQ-UHFFFAOYSA-N cyclohexanecarbonitrile Chemical class N#CC1CCCCC1 VBWIZSYFQSOUFQ-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000008569 process Effects 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- HGCIXCUEYOPUTN-UHFFFAOYSA-N cyclohexene Chemical compound C1CCC=CC1 HGCIXCUEYOPUTN-UHFFFAOYSA-N 0.000 abstract 2
- -1 4-substituted-4-(3,4-disubstituted phenyl)-cyclohexanecarboxylic acids Chemical class 0.000 abstract 1
- NMEZJSDUZQOPFE-UHFFFAOYSA-N Cyclohex-1-enecarboxylic acid Chemical class OC(=O)C1=CCCCC1 NMEZJSDUZQOPFE-UHFFFAOYSA-N 0.000 abstract 1
- 101100296720 Dictyostelium discoideum Pde4 gene Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 101100082610 Plasmodium falciparum (isolate 3D7) PDEdelta gene Proteins 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000008570 general process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/24—Preparation of carboxylic acid nitriles by ammoxidation of hydrocarbons or substituted hydrocarbons
- C07C253/28—Preparation of carboxylic acid nitriles by ammoxidation of hydrocarbons or substituted hydrocarbons containing six-membered aromatic rings, e.g. styrene
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
A találmány szerinti eljárással olyan (I) általános képletű vegyületek- amelyek képletében Ar egy aromás csoportot jelent - állíthatók elő.Az eljárás során egy (A) általános képletű ciklohexént redukálnak. Atalálmány tárgya továbbá az a,b - telítetlen ciklohexén - karbonsavakredukálására szolgáló általános eljárás. A találmány szerinti eljárásés a találmány szerinti intermedierek lehetőséget nyújtanak bizonyos4-szubsztituált-4-(3,4-diszubsztituált fenil)-ciklohexánkarbonsavakelőállítására, amely vegyületek az asztma és más olyan betegségekkezelésére alkalmazhatók, amely betegségek a PDE4 enzimbefolyásolásával enyhíthetők. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17572000P | 2000-01-12 | 2000-01-12 | |
| PCT/US2001/001083 WO2001051455A1 (en) | 2000-01-12 | 2001-01-12 | Process and intermediates for preparing a cyclohexylnitrile |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0204270A2 true HUP0204270A2 (hu) | 2003-04-28 |
| HUP0204270A3 HUP0204270A3 (en) | 2005-05-30 |
Family
ID=22641372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0204270A HUP0204270A3 (en) | 2000-01-12 | 2001-01-12 | Process for preparing cyclohexancarbonitrile derivatives and their intermediates |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1246794A4 (hu) |
| JP (1) | JP2004500372A (hu) |
| KR (1) | KR20020073164A (hu) |
| CN (1) | CN1416417A (hu) |
| AR (1) | AR029788A1 (hu) |
| AU (1) | AU2941301A (hu) |
| BR (1) | BR0107494A (hu) |
| CA (1) | CA2397296A1 (hu) |
| HK (1) | HK1050672A1 (hu) |
| HU (1) | HUP0204270A3 (hu) |
| IL (1) | IL150399A0 (hu) |
| MX (1) | MXPA02006839A (hu) |
| NO (1) | NO20023330L (hu) |
| NZ (1) | NZ519800A (hu) |
| PL (1) | PL366004A1 (hu) |
| WO (1) | WO2001051455A1 (hu) |
| ZA (1) | ZA200205391B (hu) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0633776B1 (en) * | 1992-04-02 | 2001-05-09 | Smithkline Beecham Corporation | Compounds useful for treating allergic and inflammatory diseases |
-
2001
- 2001-01-10 AR ARP010100094A patent/AR029788A1/es not_active Application Discontinuation
- 2001-01-12 CN CN01803723A patent/CN1416417A/zh active Pending
- 2001-01-12 WO PCT/US2001/001083 patent/WO2001051455A1/en not_active Application Discontinuation
- 2001-01-12 KR KR1020027008983A patent/KR20020073164A/ko not_active Application Discontinuation
- 2001-01-12 EP EP01942356A patent/EP1246794A4/en not_active Withdrawn
- 2001-01-12 NZ NZ519800A patent/NZ519800A/en unknown
- 2001-01-12 JP JP2001551837A patent/JP2004500372A/ja not_active Withdrawn
- 2001-01-12 HU HU0204270A patent/HUP0204270A3/hu unknown
- 2001-01-12 CA CA002397296A patent/CA2397296A1/en not_active Abandoned
- 2001-01-12 IL IL15039901A patent/IL150399A0/xx unknown
- 2001-01-12 PL PL01366004A patent/PL366004A1/xx unknown
- 2001-01-12 BR BR0107494-6A patent/BR0107494A/pt not_active IP Right Cessation
- 2001-01-12 MX MXPA02006839A patent/MXPA02006839A/es unknown
- 2001-01-12 AU AU29413/01A patent/AU2941301A/en not_active Abandoned
-
2002
- 2002-07-05 ZA ZA200205391A patent/ZA200205391B/en unknown
- 2002-07-10 NO NO20023330A patent/NO20023330L/no not_active Application Discontinuation
-
2003
- 2003-02-27 HK HK03101476.8A patent/HK1050672A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA02006839A (es) | 2002-10-23 |
| ZA200205391B (en) | 2003-10-03 |
| NZ519800A (en) | 2004-11-26 |
| NO20023330L (no) | 2002-09-04 |
| KR20020073164A (ko) | 2002-09-19 |
| CN1416417A (zh) | 2003-05-07 |
| BR0107494A (pt) | 2003-07-29 |
| IL150399A0 (en) | 2002-12-01 |
| HUP0204270A3 (en) | 2005-05-30 |
| WO2001051455A1 (en) | 2001-07-19 |
| NO20023330D0 (no) | 2002-07-10 |
| HK1050672A1 (zh) | 2003-07-04 |
| AU2941301A (en) | 2001-07-24 |
| EP1246794A1 (en) | 2002-10-09 |
| JP2004500372A (ja) | 2004-01-08 |
| AR029788A1 (es) | 2003-07-16 |
| EP1246794A4 (en) | 2005-10-05 |
| CA2397296A1 (en) | 2001-07-19 |
| PL366004A1 (en) | 2005-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |