HUP0204187A3 - Process for the preparation of 1-oxo-1,3-dihydro-5-isobenzofurancarboxylic acid and its use for the production of citalopram - Google Patents

Process for the preparation of 1-oxo-1,3-dihydro-5-isobenzofurancarboxylic acid and its use for the production of citalopram

Info

Publication number
HUP0204187A3
HUP0204187A3 HU0204187A HUP0204187A HUP0204187A3 HU P0204187 A3 HUP0204187 A3 HU P0204187A3 HU 0204187 A HU0204187 A HU 0204187A HU P0204187 A HUP0204187 A HU P0204187A HU P0204187 A3 HUP0204187 A3 HU P0204187A3
Authority
HU
Hungary
Prior art keywords
citalopram
dihydro
oxo
preparation
production
Prior art date
Application number
HU0204187A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Infosint S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26332721&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0204187(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Infosint S A filed Critical Infosint S A
Publication of HUP0204187A2 publication Critical patent/HUP0204187A2/hu
Publication of HUP0204187A3 publication Critical patent/HUP0204187A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Seasonings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HU0204187A 2000-01-18 2001-01-17 Process for the preparation of 1-oxo-1,3-dihydro-5-isobenzofurancarboxylic acid and its use for the production of citalopram HUP0204187A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT2000MI000050A IT1317729B1 (it) 2000-01-18 2000-01-18 Procedimento per la preparazione della 5-carbossiftalide.
US09/690,301 US6458973B1 (en) 2000-01-18 2000-10-17 Process for the preparation of 5-carboxyphthalide
PCT/EP2001/000617 WO2001053284A1 (en) 2000-01-18 2001-01-17 Process for the preparation of 5-carboxyphthalide and its use for the production of citalopram

Publications (2)

Publication Number Publication Date
HUP0204187A2 HUP0204187A2 (hu) 2003-03-28
HUP0204187A3 true HUP0204187A3 (en) 2005-05-30

Family

ID=26332721

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0204187A HUP0204187A3 (en) 2000-01-18 2001-01-17 Process for the preparation of 1-oxo-1,3-dihydro-5-isobenzofurancarboxylic acid and its use for the production of citalopram

Country Status (21)

Country Link
US (4) US6458973B1 (https=)
EP (2) EP1118614B2 (https=)
JP (1) JP4558182B2 (https=)
CN (1) CN1184220C (https=)
AT (1) ATE219489T1 (https=)
AU (1) AU779581B2 (https=)
BG (1) BG65763B1 (https=)
BR (1) BR0107853A (https=)
CA (1) CA2397497C (https=)
DE (1) DE60000226T3 (https=)
DK (1) DK1118614T4 (https=)
ES (1) ES2178626T5 (https=)
HK (1) HK1042290B (https=)
HU (1) HUP0204187A3 (https=)
IT (1) IT1317729B1 (https=)
MX (1) MXPA02007031A (https=)
PL (1) PL356563A1 (https=)
PT (1) PT1118614E (https=)
RO (1) RO121737B1 (https=)
WO (1) WO2001053284A1 (https=)
ZA (1) ZA200205475B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR026063A1 (es) * 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
CN1427835A (zh) * 2000-03-13 2003-07-02 H·隆德贝克有限公司 5－取代的1－(4－氟苯基)－1,3－二氢异苯并呋喃的分步烷基化
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
US7687645B2 (en) * 2003-03-21 2010-03-30 H. Lundbeck A/S Intermediates for the preparation of citalopram and escitalopram
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
WO2006090409A1 (en) * 2005-02-28 2006-08-31 Kekule Pharma Ltd., An improved process for the preparation of 5 - carboxyphthalide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3607884A (en) * 1969-03-11 1971-09-21 Mobil Oil Corp Preparation of 5-carboxyphthalide in liquid sodium trioxide
US3976751A (en) † 1974-10-21 1976-08-24 Allied Chemical Corporation Stabilization of liquid sulfur trioxide
DE2630927A1 (de) 1976-07-09 1978-01-19 Basf Ag Verfahren zur herstellung von phthalidcarbonsaeure-(5)
DE3605716A1 (de) 1986-02-22 1987-09-03 Henkel Kgaa Verwendung von unloeslichen schmutzsammlern zur regenerierung von wasch- und reinigungsloesungen
WO1998019513A2 (en) * 1997-07-08 1998-05-14 H. Lundbeck A/S Method for the preparation of citalopram
CA2291134C (en) * 1998-10-20 2006-05-23 H. Lundbeck A/S Method for the preparation of citalopram
AR026063A1 (es) * 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
AU1130901A (en) 1999-11-01 2001-05-14 H. Lundbeck A/S Method for the preparation of 5-carboxyphthalide
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram

Also Published As

Publication number Publication date
ES2178626T3 (es) 2003-01-01
ES2178626T5 (es) 2011-06-02
DE60000226T3 (de) 2012-02-16
US6703516B2 (en) 2004-03-09
MXPA02007031A (es) 2004-09-06
AU2679801A (en) 2001-07-31
JP4558182B2 (ja) 2010-10-06
BG106925A (bg) 2004-01-30
WO2001053284A1 (en) 2001-07-26
JP2001206881A (ja) 2001-07-31
DK1118614T3 (da) 2002-10-14
HK1042290A1 (en) 2002-08-09
AU779581B2 (en) 2005-01-27
ZA200205475B (en) 2003-12-31
DE60000226D1 (de) 2002-07-25
EP1118614A2 (en) 2001-07-25
CA2397497C (en) 2010-07-06
IT1317729B1 (it) 2003-07-15
EP1187822A1 (en) 2002-03-20
EP1118614B1 (en) 2002-06-19
ATE219489T1 (de) 2002-07-15
BR0107853A (pt) 2002-10-29
DK1118614T4 (da) 2011-06-27
DE60000226T2 (de) 2003-03-06
ITMI20000050A0 (it) 2000-01-18
US20080249319A1 (en) 2008-10-09
US20040171851A1 (en) 2004-09-02
US20030009038A1 (en) 2003-01-09
PT1118614E (pt) 2002-11-29
ITMI20000050A1 (it) 2001-07-18
CN1406236A (zh) 2003-03-26
EP1118614A3 (en) 2001-10-24
HUP0204187A2 (hu) 2003-03-28
HK1042290B (en) 2003-07-18
EP1118614B2 (en) 2011-03-09
US6458973B1 (en) 2002-10-01
CA2397497A1 (en) 2001-07-26
RO121737B1 (ro) 2008-03-28
BG65763B1 (bg) 2009-10-30
CN1184220C (zh) 2005-01-12
PL356563A1 (en) 2004-06-28

Similar Documents

Publication Publication Date Title
GB2356199B (en) Process for the preparation of pure citalopram
ZA200110179B (en) Process for the preparation of pure citalopram.
HUP0103291A3 (en) Process for the preparation of citalopram
IL146389A0 (en) Process for the preparation of dronedarone
HUP0300592A3 (en) Process for the preparation of 2-halobenzoic acid derivatives
IL161026A0 (en) Process for the preparation of citalopram
HUP0204187A3 (en) Process for the preparation of 1-oxo-1,3-dihydro-5-isobenzofurancarboxylic acid and its use for the production of citalopram
IL157709A0 (en) Process for the preparation of 1,2-benzisoxazole-3-acetic acid
NO20025423L (no) Fremgangsmate for fremstilling av Citalopram
AU8824201A (en) Process for the preparation of dinapsoline
IL139023A0 (en) Process for the preparation of 2,3,5-trimethyl-p- benzoquinone
NO20021118D0 (no) Fremgangsmåte for fremstilling av citalopram
EG22846A (en) Process for the preparation of urea
SG95675A1 (en) Process for the preparation of 2,6-xylenol
IL137364A (en) Process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol
EG22758A (en) Process for the preparation of urea
HUP0301515A3 (en) Process for the preparation of chiral 1,4-diaryl-2-fluoro-2-butenes and their intermediates
GB2359811B (en) Process for the preparation of pure citalopram
SI1181272T1 (en) Process for the preparation of pure citalopram
HRP20030811A2 (en) Process for the preparation of citalopram
SI1258490T1 (en) Process for preparing indolopyrrolocarbazole derivatives, intermediates thereof, and preparation process of the intermediates
HUP0301293A3 (en) Process for the preparation of mycophenolic acid and derivatives thereof
GB0012249D0 (en) Process for the preparation of 11-oxaprostaglandins
IL140127A0 (en) Process for the preparation of optically active 1,4-benzodixoane-2-carboxylic acid and derivatives thereof
EP1215314A3 (de) Garn, Verwendung des Garnes sowie Verfahren zur Herstellung dieses Garnes

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees