HUP0103859A2 - Fungicid és inszekticid hatású pirimidin-4-enaminok, intermedierjeik, előállításuk és alkalmazásuk - Google Patents
Fungicid és inszekticid hatású pirimidin-4-enaminok, intermedierjeik, előállításuk és alkalmazásukInfo
- Publication number
- HUP0103859A2 HUP0103859A2 HU0103859A HUP0103859A HUP0103859A2 HU P0103859 A2 HUP0103859 A2 HU P0103859A2 HU 0103859 A HU0103859 A HU 0103859A HU P0103859 A HUP0103859 A HU P0103859A HU P0103859 A2 HUP0103859 A2 HU P0103859A2
- Authority
- HU
- Hungary
- Prior art keywords
- alkynyl
- alkenyl
- optionally substituted
- substituted alkyl
- cycloalkyl
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 230000000855 fungicidal effect Effects 0.000 title abstract 2
- 230000000749 insecticidal effect Effects 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 6
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 6
- 125000000304 alkynyl group Chemical group 0.000 abstract 5
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 5
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 2
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 2
- 125000005108 alkenylthio group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000005133 alkynyloxy group Chemical group 0.000 abstract 2
- 125000005109 alkynylthio group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 241000233866 Fungi Species 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 241000607479 Yersinia pestis Species 0.000 abstract 1
- 239000003905 agrochemical Substances 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000005223 heteroarylcarbonyl group Chemical group 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 230000000361 pesticidal effect Effects 0.000 abstract 1
- 125000005359 phenoxyalkyl group Chemical group 0.000 abstract 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 abstract 1
- 150000003230 pyrimidines Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A találmány peszticid, különösen fungicid és inszekticid hatássalrendelkező, pirimidinszármazékokra, valamint lehetséges izomereikre ésizomerkeverékeikre vonatkozik, amelyek (I) általános képletében Atelített vagy telítetlen, aromás vagy nem aromás, adott esetben 1-3oxigén-, kén- és/vagy nitrogénatom heteroatomot tartalmazó öt- vagyhattagú gyűrű, kivéve az imidazolgyűrűt; Rl, R2 és R3 hidrogénatom;halogénatom; adott esetben szubsztituált alkil-, alkenil-, alkinil-,alkoxi-, alkenil-oxi-, alkinil-oxi-, alkil-tio-, alkenil-tio- vagyalkinil-tiocsoport; ciano-, nitro- vagy trimetil-szililcsoport; azzala megkötéssel, hogy R1, R2 és R3 egyidejűleg nem lehet hidrogénatom;R4 adott esetben szubsztituált alkil-, alkenil-, alkinil-,cikloalkil-, fenil- vagy benzilcsoport; -NHR7; -SR7 vagy -OR7általános képletű csoport; R5 adott esetben szubsztituált alkil-,alkenil-, alkinil-, cikloalkilcsoport; R6 hidrogénatom, adott esetbenszubsztituált alkil-, alkenil-, alkinil-, cikloalkil-, alkoxi-,alkenil-oxi-, alkinil-oxi-, alkil-tio-, alkenil-tio-, alkinil-tio-,aril-, heteroaril-, alkil-karbonil-, (alkoxi-alkil)-karbonil-,(halogén-alkil)-karbonil-, heteroaril-karbonil-, alkil-szulfonil-,aril-szulfonil-, benzoil- vagy (fenoxi-alkil)-karbonil-, -COOR8csoport, amelyben R8 adott esetben szubsztituált alkil-, alkenil-,alkinil-, cikloalkil- vagy fenilcsoport; ciano-, nitrocsoport; vagyhalogénatom; és R7 adott esetben szubsztituált alkil-, alkenil-,alkinil-; cikloalkil-, fenil- vagy benzilcsoport. A találmány magábanfoglalja a vegyületek új intermedierjeit, és ezek előállításieljárásait, a vegyületek legalább egyikét hatóanyagként tartalmazóagrokémiai készítményeket, valamint a hatóanyagoknak vagykészítményeknek kártevők, különösen gombák visszaszorítására történőmezőgazdasági vagy kertészeti alkalmazását is. Ó
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9824332.2A GB9824332D0 (en) | 1998-11-06 | 1998-11-06 | Organic compounds |
GBGB9824906.3A GB9824906D0 (en) | 1998-11-13 | 1998-11-13 | Organic compounds |
PCT/EP1999/008447 WO2000031082A1 (en) | 1998-11-06 | 1999-11-04 | Pyrimidin-4-enamine as fungicide |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0103859A2 true HUP0103859A2 (hu) | 2002-01-28 |
HUP0103859A3 HUP0103859A3 (en) | 2002-04-29 |
Family
ID=26314629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0103859A HUP0103859A3 (en) | 1998-11-06 | 1999-11-04 | Fungicidal and insecticidal pyrimidin-4-enamines, intermediates, preparation and use thereof |
Country Status (15)
Country | Link |
---|---|
US (1) | US6617330B2 (hu) |
EP (1) | EP1124830A1 (hu) |
JP (1) | JP2002530409A (hu) |
KR (1) | KR20010083952A (hu) |
CN (1) | CN1328561A (hu) |
AR (1) | AR021087A1 (hu) |
AU (1) | AU1160200A (hu) |
BR (1) | BR9915128A (hu) |
CA (1) | CA2348557A1 (hu) |
GT (1) | GT199900185A (hu) |
HU (1) | HUP0103859A3 (hu) |
PL (1) | PL347573A1 (hu) |
RU (1) | RU2001114583A (hu) |
TR (1) | TR200101298T2 (hu) |
WO (1) | WO2000031082A1 (hu) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7687434B2 (en) * | 2000-12-22 | 2010-03-30 | Monsanto Technology, Llc | Method of improving yield and vigor of plants |
US7081460B2 (en) * | 2001-04-09 | 2006-07-25 | Ortho-Mcneil Pharmaceutical, Inc. | Quinazoline and quinazoline-like compounds for the treatment of integrin-mediated disorders |
MXPA04003445A (es) | 2001-10-15 | 2004-07-08 | Du Pont | Iminobenzoxazinas imnobenztiazinas e iminoquinazolinas para controlar pestes de invertebrados. |
WO2005115148A1 (en) * | 2004-05-24 | 2005-12-08 | Cropsolution, Inc. | 3-aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides |
US7338967B2 (en) * | 2004-09-10 | 2008-03-04 | Syngenta Limited | Substituted isoxazoles as fungicides |
EP2562162B1 (en) | 2008-01-22 | 2015-08-19 | Dow AgroSciences LLC | N-cyano-4-amino-5-fluoro-pyrimidine derivatives as fungicides |
CN101268780B (zh) * | 2008-05-08 | 2010-07-21 | 华中师范大学 | 一种甲氧基丙烯酸酯类杀菌剂、制备方法及用途 |
JP5291994B2 (ja) * | 2008-06-11 | 2013-09-18 | 日本理化学薬品株式会社 | イソチアゾリジン化合物および工業用殺菌組成物 |
UA106889C2 (uk) * | 2009-08-07 | 2014-10-27 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Похідні n1-ацил-5-фторпіримідинону |
UA107671C2 (en) * | 2009-08-07 | 2015-02-10 | Dow Agrosciences Llc | N1-substityted-5-fluoro-2-oxopyrimidinone-1(2h)-carboxamide derivatives |
US9006259B2 (en) | 2009-08-07 | 2015-04-14 | Dow Agrosciences Llc | N1-sulfonyl-5-fluoropyrimidinone derivatives |
UA112284C2 (uk) * | 2009-08-07 | 2016-08-25 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Похідні 5-фторпіримідинону |
RU2547721C2 (ru) * | 2010-01-07 | 2015-04-10 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | ТИАЗОЛО [5, 4-d] ПИРИМИДИНЫ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ АГРОХИМИЧЕСКИХ СРЕДСТВ |
UA108101C2 (xx) * | 2010-04-26 | 2015-03-25 | Похідні n3-заміщених n1-сульфоніл-5-фторпіримідинонів | |
CN106977462B (zh) * | 2011-08-17 | 2020-04-28 | 阿达玛马克西姆股份有限公司 | 5-氟-4-亚氨基-3-(取代的)-3,4-二氢嘧啶-2(1h)酮衍生物 |
CN110003118A (zh) * | 2012-12-28 | 2019-07-12 | 阿达玛马克西姆股份有限公司 | 制备羧酸酯衍生物的方法 |
EP3689142A1 (en) | 2012-12-28 | 2020-08-05 | Adama Makhteshim Ltd. | 1-(substituted-benzoyl)-5-fluoro-4-imino-3-methyl-3,4-dihydropyrimidin-2(1h)-one derivatives |
EP2945634A4 (en) | 2012-12-28 | 2016-05-25 | Dow Agrosciences Llc | N- (SUBSTITUTED) -5-FLUORO-4-IMINO-3-METHYL-2-OXO-3,4-DIHYDROPYRIMIDIN-1 (2H) -CARBOXAMIDE DERIVATIVES |
PL2953463T3 (pl) * | 2012-12-31 | 2022-01-03 | Adama Makhteshim Ltd. | Pochodne 3-alkilo-5-fluoro-4-podstawione-imino-3,4-dihydropirymidyn-2(1h)-onu jako środki grzybobójcze |
PE20161174A1 (es) | 2013-12-31 | 2016-10-26 | Adama Makhteshim Ltd | 5-fluor-4-imino-3-(alquil/alquilo sustituido)-1-(arilsulfonil)-3,4-dihidropirimidin-2(1h)-ona y los procesos para su preparacion |
AU2014373850A1 (en) | 2013-12-31 | 2016-08-11 | Adama Makhteshim Ltd. | Synergistic fungicidal mixtures and compositions for fungal control |
CN104151255B (zh) * | 2014-07-22 | 2016-07-13 | 清华大学 | 一种多取代喹唑啉亚胺衍生物及其制备方法 |
JP2020503377A (ja) | 2016-12-13 | 2020-01-30 | ベータ セラピューティクス プロプライアタリー リミティド | ヘパラナーゼ阻害剤及びそれの使用 |
US11787783B2 (en) | 2016-12-13 | 2023-10-17 | Beta Therapeutics Pty Ltd | Heparanase inhibitors and use thereof |
AU2017376818A1 (en) * | 2016-12-13 | 2019-07-11 | Beta Therapeutics Pty Ltd | Heparanase inhibitors and use thereof |
IL309708A (en) | 2017-07-17 | 2024-02-01 | Adama Makhteshim Ltd | Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-4,3-dihydropyrimidin-2-one |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5668154A (en) * | 1995-06-06 | 1997-09-16 | Hoechst Marion Roussel Inc. | Pyridiniminyl-1,2-benzisoxazoles and -benzisothiazoles |
DE69712331T2 (de) * | 1996-03-11 | 2002-11-28 | Syngenta Participations Ag | Pyrimidin-4-on derivate als pestizidesmittel |
GB9719411D0 (en) * | 1997-09-12 | 1997-11-12 | Ciba Geigy Ag | New Pesticides |
-
1999
- 1999-10-26 GT GT199900185A patent/GT199900185A/es unknown
- 1999-11-04 AR ARP990105586A patent/AR021087A1/es not_active Application Discontinuation
- 1999-11-04 KR KR1020017005651A patent/KR20010083952A/ko not_active Application Discontinuation
- 1999-11-04 CN CN99813855A patent/CN1328561A/zh active Pending
- 1999-11-04 WO PCT/EP1999/008447 patent/WO2000031082A1/en not_active Application Discontinuation
- 1999-11-04 RU RU2001114583/04A patent/RU2001114583A/ru unknown
- 1999-11-04 HU HU0103859A patent/HUP0103859A3/hu unknown
- 1999-11-04 CA CA002348557A patent/CA2348557A1/en not_active Abandoned
- 1999-11-04 TR TR2001/01298T patent/TR200101298T2/xx unknown
- 1999-11-04 BR BR9915128-6A patent/BR9915128A/pt not_active IP Right Cessation
- 1999-11-04 PL PL99347573A patent/PL347573A1/xx not_active Application Discontinuation
- 1999-11-04 JP JP2000583910A patent/JP2002530409A/ja active Pending
- 1999-11-04 AU AU11602/00A patent/AU1160200A/en not_active Abandoned
- 1999-11-04 EP EP99972636A patent/EP1124830A1/en not_active Ceased
-
2001
- 2001-05-04 US US09/849,931 patent/US6617330B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
GT199900185A (es) | 2001-04-18 |
US20030040521A1 (en) | 2003-02-27 |
EP1124830A1 (en) | 2001-08-22 |
WO2000031082A1 (en) | 2000-06-02 |
AU1160200A (en) | 2000-06-13 |
AR021087A1 (es) | 2002-06-12 |
US6617330B2 (en) | 2003-09-09 |
HUP0103859A3 (en) | 2002-04-29 |
CN1328561A (zh) | 2001-12-26 |
CA2348557A1 (en) | 2000-06-02 |
WO2000031082A8 (en) | 2000-08-03 |
RU2001114583A (ru) | 2004-03-20 |
TR200101298T2 (tr) | 2001-10-22 |
BR9915128A (pt) | 2001-07-31 |
JP2002530409A (ja) | 2002-09-17 |
KR20010083952A (ko) | 2001-09-03 |
PL347573A1 (en) | 2002-04-08 |
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