HUP0103428A2 - Új eljárás optikailag aktív alfa-amino-nitrilek előállítására - Google Patents
Új eljárás optikailag aktív alfa-amino-nitrilek előállításáraInfo
- Publication number
- HUP0103428A2 HUP0103428A2 HU0103428A HUP0103428A HUP0103428A2 HU P0103428 A2 HUP0103428 A2 HU P0103428A2 HU 0103428 A HU0103428 A HU 0103428A HU P0103428 A HUP0103428 A HU P0103428A HU P0103428 A2 HUP0103428 A2 HU P0103428A2
- Authority
- HU
- Hungary
- Prior art keywords
- aminonitriles
- optically active
- novel method
- general formula
- preparing optically
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000004696 coordination complex Chemical class 0.000 abstract 1
- 239000000411 inducer Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000004658 ketimines Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000002894 organic compounds Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2204—Organic complexes the ligands containing oxygen or sulfur as complexing atoms
- B01J31/2208—Oxygen, e.g. acetylacetonates
- B01J31/2226—Anionic ligands, i.e. the overall ligand carries at least one formal negative charge
- B01J31/223—At least two oxygen atoms present in one at least bidentate or bridging ligand
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/22—Organic complexes
- B01J31/2204—Organic complexes the ligands containing oxygen or sulfur as complexing atoms
- B01J31/226—Sulfur, e.g. thiocarbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/08—Preparation of carboxylic acid nitriles by addition of hydrogen cyanide or salts thereof to unsaturated compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/20—Free hydroxyl or mercaptan
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/30—Addition reactions at carbon centres, i.e. to either C-C or C-X multiple bonds
- B01J2231/32—Addition reactions to C=C or C-C triple bonds
- B01J2231/322—Hydrocyanation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/02—Compositional aspects of complexes used, e.g. polynuclearity
- B01J2531/0213—Complexes without C-metal linkages
- B01J2531/0216—Bi- or polynuclear complexes, i.e. comprising two or more metal coordination centres, without metal-metal bonds, e.g. Cp(Lx)Zr-imidazole-Zr(Lx)Cp
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/30—Complexes comprising metals of Group III (IIIA or IIIB) as the central metal
- B01J2531/31—Aluminium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/30—Complexes comprising metals of Group III (IIIA or IIIB) as the central metal
- B01J2531/32—Gallium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/30—Complexes comprising metals of Group III (IIIA or IIIB) as the central metal
- B01J2531/35—Scandium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/30—Complexes comprising metals of Group III (IIIA or IIIB) as the central metal
- B01J2531/38—Lanthanides other than lanthanum
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/40—Complexes comprising metals of Group IV (IVA or IVB) as the central metal
- B01J2531/46—Titanium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/40—Complexes comprising metals of Group IV (IVA or IVB) as the central metal
- B01J2531/48—Zirconium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/40—Complexes comprising metals of Group IV (IVA or IVB) as the central metal
- B01J2531/49—Hafnium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/84—Metals of the iron group
- B01J2531/842—Iron
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
A találmány új eljárásra vonatkozik (I) általános képletű optikailagaktív a-aminonitrilek előállítására. Az eljárás során (II) általánosképletű ketimineket hidrociánoznak hidrociánozó reagens segítségévelkatalizátorként ható királis vagy kiralitás induktor fém-komplexjelenlétében. A képletekben R1, R2 és T jelentése a leírás szerinti.Az (I) általános képletű a-aminonitrileket optikailag aktív szervesvegyületek szintéziséhez intermedierként lehet felhasználni. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9907512A FR2794743A1 (fr) | 1999-06-09 | 1999-06-09 | Nouveau procede de preparation d'alpha-aminonitriles optiquement actifs |
PCT/FR2000/001597 WO2000075104A1 (fr) | 1999-06-09 | 2000-06-09 | NOUVEAU PROCEDE DE PREPARATION D'α-AMINONITRILES OPTIQUEMENT ACTIFS |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0103428A2 true HUP0103428A2 (hu) | 2002-01-28 |
Family
ID=9546766
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0103428A HUP0103428A2 (hu) | 1999-06-09 | 2000-06-09 | Új eljárás optikailag aktív alfa-amino-nitrilek előállítására |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1102744A1 (hu) |
JP (1) | JP2003501411A (hu) |
KR (1) | KR20010072385A (hu) |
CN (1) | CN1314880A (hu) |
AU (1) | AU5540900A (hu) |
BR (1) | BR0006829A (hu) |
FR (1) | FR2794743A1 (hu) |
HU (1) | HUP0103428A2 (hu) |
PL (1) | PL345995A1 (hu) |
TR (1) | TR200100435T1 (hu) |
WO (1) | WO2000075104A1 (hu) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2398569B (en) * | 2003-02-19 | 2006-12-27 | Merck Patent Gmbh | Chiral compounds comprising Group IV element with two 1,1'-binaphth-2,2'-diyl-containing or related substituents |
US20100179343A1 (en) * | 2007-03-29 | 2010-07-15 | Agency For Science, Technology And Research | Method of producing an optically active cyanohydrin derivative |
JP5426556B2 (ja) * | 2007-09-28 | 2014-02-26 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | イミンの不斉シアノ化方法 |
WO2010071227A1 (en) * | 2008-12-17 | 2010-06-24 | Takasago International Corporation | Aluminium complexes and use thereof as a catalyst in intramolecular ring closure reactions |
JP5501701B2 (ja) * | 2009-09-09 | 2014-05-28 | 三井化学株式会社 | イミンの不斉シアノ化方法 |
CN103342652B (zh) * | 2013-07-24 | 2015-02-25 | 重庆紫光化工股份有限公司 | N,n-二甲基氨基乙酸酯的制备方法 |
CN103962180B (zh) * | 2013-08-06 | 2016-02-17 | 汕头大学 | 用于制备α-氨基腈的Salen配位聚合物催化剂及其制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2706456B1 (fr) * | 1993-06-18 | 1996-06-28 | Rhone Poulenc Agrochimie | Dérivés optiquement actifs de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides. |
FR2751327A1 (fr) * | 1996-07-22 | 1998-01-23 | Rhone Poulenc Agrochimie | Intermediaires pour la preparation de 2-imidazoline-5-ones |
-
1999
- 1999-06-09 FR FR9907512A patent/FR2794743A1/fr not_active Withdrawn
-
2000
- 2000-06-09 CN CN00801171A patent/CN1314880A/zh active Pending
- 2000-06-09 TR TR2001/00435T patent/TR200100435T1/xx unknown
- 2000-06-09 JP JP2001501585A patent/JP2003501411A/ja not_active Withdrawn
- 2000-06-09 HU HU0103428A patent/HUP0103428A2/hu unknown
- 2000-06-09 EP EP00940478A patent/EP1102744A1/fr not_active Withdrawn
- 2000-06-09 WO PCT/FR2000/001597 patent/WO2000075104A1/fr not_active Application Discontinuation
- 2000-06-09 AU AU55409/00A patent/AU5540900A/en not_active Abandoned
- 2000-06-09 BR BR0006829-2A patent/BR0006829A/pt not_active IP Right Cessation
- 2000-06-09 KR KR1020017001744A patent/KR20010072385A/ko not_active Application Discontinuation
- 2000-06-09 PL PL00345995A patent/PL345995A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
BR0006829A (pt) | 2001-10-30 |
FR2794743A1 (fr) | 2000-12-15 |
WO2000075104A1 (fr) | 2000-12-14 |
PL345995A1 (en) | 2002-01-14 |
EP1102744A1 (fr) | 2001-05-30 |
CN1314880A (zh) | 2001-09-26 |
TR200100435T1 (tr) | 2001-08-21 |
KR20010072385A (ko) | 2001-07-31 |
JP2003501411A (ja) | 2003-01-14 |
AU5540900A (en) | 2000-12-28 |
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