HUP0102807A2 - Karnitint és karotenoidet tartalmazó antioxidáns, antiproliferációs készítmény - Google Patents
Karnitint és karotenoidet tartalmazó antioxidáns, antiproliferációs készítményInfo
- Publication number
- HUP0102807A2 HUP0102807A2 HU0102807A HUP0102807A HUP0102807A2 HU P0102807 A2 HUP0102807 A2 HU P0102807A2 HU 0102807 A HU0102807 A HU 0102807A HU P0102807 A HUP0102807 A HU P0102807A HU P0102807 A2 HUP0102807 A2 HU P0102807A2
- Authority
- HU
- Hungary
- Prior art keywords
- carotenoid
- carnitine
- antiproliferous
- antioxidant
- composition
- Prior art date
Links
- 235000021466 carotenoid Nutrition 0.000 title abstract 2
- 150000001747 carotenoids Chemical class 0.000 title abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 title 1
- 230000003078 antioxidant effect Effects 0.000 title 1
- 229960004203 carnitine Drugs 0.000 title 1
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 abstract 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 abstract 1
- JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 abstract 1
- UFAHZIUFPNSHSL-MRVPVSSYSA-N O-propanoyl-L-carnitine Chemical compound CCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C UFAHZIUFPNSHSL-MRVPVSSYSA-N 0.000 abstract 1
- 240000003768 Solanum lycopersicum Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000002248 lipoperoxidative effect Effects 0.000 abstract 1
- OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 abstract 1
- 229960004999 lycopene Drugs 0.000 abstract 1
- 235000012661 lycopene Nutrition 0.000 abstract 1
- 239000001751 lycopene Substances 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Botany (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
A találmány hatóanyagként propionil-L-karnitint és legalább egykarotenoidot, mégpedig jellemzően paradicsomból extrahált likopénttartalmazó gyógyszerkészítményre vonatkozik, amely szabad gyökök éslipoperoxidációs jelenség által kiváltott különböző elváltozások éskóros állapotok megelőzésére és/vagy gyógyászati kezelésére alkalmas.A készítmények táplálkozási kiegészítők, élelmiszer-hordozók vagygyógyszer formában állíthatók elő. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1998RM000516A IT1302125B1 (it) | 1998-08-03 | 1998-08-03 | Composizione ad attivita' antiossidante ed antiproliferativacomprendente una carnitina ed un carotenoide |
PCT/IT1999/000251 WO2000007581A2 (en) | 1998-08-03 | 1999-07-29 | Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0102807A2 true HUP0102807A2 (hu) | 2002-03-28 |
Family
ID=11406082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0102807A HUP0102807A2 (hu) | 1998-08-03 | 1999-07-29 | Karnitint és karotenoidet tartalmazó antioxidáns, antiproliferációs készítmény |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1102584A2 (hu) |
JP (1) | JP2002522382A (hu) |
KR (1) | KR20010072146A (hu) |
CN (1) | CN1311674A (hu) |
AR (1) | AR021172A1 (hu) |
AU (1) | AU5064199A (hu) |
BR (1) | BR9912703A (hu) |
CA (1) | CA2338035A1 (hu) |
EE (1) | EE200100052A (hu) |
HK (1) | HK1039062A1 (hu) |
HU (1) | HUP0102807A2 (hu) |
IL (1) | IL140797A0 (hu) |
IS (1) | IS5816A (hu) |
IT (1) | IT1302125B1 (hu) |
MA (1) | MA26666A1 (hu) |
NO (1) | NO20010532L (hu) |
PL (1) | PL346161A1 (hu) |
SK (1) | SK1252001A3 (hu) |
TN (1) | TNSN99152A1 (hu) |
TR (1) | TR200100333T2 (hu) |
WO (1) | WO2000007581A2 (hu) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1286704T3 (da) | 2000-06-02 | 2014-09-22 | Univ Texas | Ethylendicystein (EC)-glucose analoge konjugater |
US6923960B2 (en) | 2001-10-03 | 2005-08-02 | Vsl Pharmaceuticals Inc. | Antioxidant combination composition and use thereof |
KR100523562B1 (ko) | 2001-10-29 | 2005-10-25 | 한국과학기술연구원 | 손바닥선인장 추출물 및 이로부터 분리된 화합물을함유하는 신경세포 보호용 조성물 |
JP4527938B2 (ja) * | 2002-07-23 | 2010-08-18 | オルビス株式会社 | 抗酸化用の経口投与組成物 |
JP4334189B2 (ja) * | 2002-07-30 | 2009-09-30 | カゴメ株式会社 | Age生成阻害剤 |
ITRM20020620A1 (it) * | 2002-12-13 | 2004-06-14 | Sigma Tau Ind Farmaceuti | Uso delle carnitine per la prevenzione e/o il trattamento dei disturbi causati dall'andropausa. |
ATE423109T1 (de) | 2003-04-14 | 2009-03-15 | Nippon Soda Co | Diaminderivat, herstellungsverfahren und antioxidations-arzneimittel |
US9050378B2 (en) | 2003-12-10 | 2015-06-09 | Board Of Regents, The University Of Texas System | N2S2 chelate-targeting ligand conjugates |
CA2553884C (en) * | 2004-01-28 | 2013-06-25 | Nestec S.A. | Nutritional composition for improving skin condition and preventing skin diseases |
US8758723B2 (en) | 2006-04-19 | 2014-06-24 | The Board Of Regents Of The University Of Texas System | Compositions and methods for cellular imaging and therapy |
US10925977B2 (en) | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
RU2619342C1 (ru) * | 2016-02-24 | 2017-05-15 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" | Препарат для профилактики и лечения свободнорадикальной патологии у животных |
CN113491687A (zh) * | 2020-04-02 | 2021-10-12 | 常州高新技术产业开发区三维工业技术研究所有限公司 | 一种解毒药物组合物及其用途 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU518617B2 (en) * | 1977-04-29 | 1981-10-08 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Therapeutic application of acetyl-d, 1-carnitine |
EP0400547A1 (en) * | 1989-06-02 | 1990-12-05 | Abbott Laboratories | Parenteral nutrition product |
IT1276225B1 (it) * | 1995-10-17 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per |
IT1277953B1 (it) * | 1995-12-21 | 1997-11-12 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per |
IT1283967B1 (it) * | 1996-03-29 | 1998-05-07 | Sigma Tau Ind Farmaceuti | Uso di l-carnitina o derivati della l-carnitina ed antiossidanti nella prevenzione e trattamento di patologie derivanti da danni ossidativi |
US5667791A (en) * | 1996-05-31 | 1997-09-16 | Thione International, Inc. | X-ray induced skin damage protective composition |
US5895652A (en) * | 1996-07-29 | 1999-04-20 | Longevity Institute International | Method of metabolic adjuvanation and cellular repair |
JP2001511153A (ja) * | 1997-02-04 | 2001-08-07 | ブイ. コスバブ,ジョン | 血管変性性疾患の予防および処置のための組成物および方法 |
IT1291113B1 (it) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizione nutritiva terapeutica per soggetti affetti da diabete mellito |
-
1998
- 1998-08-03 IT IT1998RM000516A patent/IT1302125B1/it active IP Right Grant
-
1999
- 1999-07-29 CA CA002338035A patent/CA2338035A1/en not_active Abandoned
- 1999-07-29 CN CN99809268A patent/CN1311674A/zh active Pending
- 1999-07-29 EE EEP200100052A patent/EE200100052A/xx unknown
- 1999-07-29 JP JP2000563266A patent/JP2002522382A/ja active Pending
- 1999-07-29 IL IL14079799A patent/IL140797A0/xx unknown
- 1999-07-29 EP EP99935044A patent/EP1102584A2/en not_active Withdrawn
- 1999-07-29 PL PL99346161A patent/PL346161A1/xx unknown
- 1999-07-29 WO PCT/IT1999/000251 patent/WO2000007581A2/en not_active Application Discontinuation
- 1999-07-29 HU HU0102807A patent/HUP0102807A2/hu unknown
- 1999-07-29 BR BR9912703-2A patent/BR9912703A/pt not_active Application Discontinuation
- 1999-07-29 KR KR1020017001339A patent/KR20010072146A/ko not_active Application Discontinuation
- 1999-07-29 SK SK125-2001A patent/SK1252001A3/sk unknown
- 1999-07-29 AU AU50641/99A patent/AU5064199A/en not_active Abandoned
- 1999-07-29 TR TR2001/00333T patent/TR200100333T2/xx unknown
- 1999-07-30 TN TNTNSN99152A patent/TNSN99152A1/fr unknown
- 1999-08-03 MA MA25710A patent/MA26666A1/fr unknown
- 1999-08-03 AR ARP990103863A patent/AR021172A1/es unknown
-
2001
- 2001-01-16 IS IS5816A patent/IS5816A/is unknown
- 2001-01-31 NO NO20010532A patent/NO20010532L/no not_active Application Discontinuation
-
2002
- 2002-01-16 HK HK02100334.3A patent/HK1039062A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AR021172A1 (es) | 2002-07-03 |
AU5064199A (en) | 2000-02-28 |
KR20010072146A (ko) | 2001-07-31 |
HK1039062A1 (zh) | 2002-04-12 |
JP2002522382A (ja) | 2002-07-23 |
SK1252001A3 (en) | 2001-08-06 |
TR200100333T2 (tr) | 2001-07-23 |
CA2338035A1 (en) | 2000-02-17 |
NO20010532L (no) | 2001-03-20 |
CN1311674A (zh) | 2001-09-05 |
IS5816A (is) | 2001-01-16 |
MA26666A1 (fr) | 2004-12-20 |
ITRM980516A0 (it) | 1998-08-03 |
WO2000007581A2 (en) | 2000-02-17 |
IT1302125B1 (it) | 2000-07-31 |
EE200100052A (et) | 2002-06-17 |
NO20010532D0 (no) | 2001-01-31 |
TNSN99152A1 (fr) | 2005-11-10 |
IL140797A0 (en) | 2002-02-10 |
ITRM980516A1 (it) | 2000-02-03 |
PL346161A1 (en) | 2002-01-28 |
WO2000007581A3 (en) | 2000-05-11 |
EP1102584A2 (en) | 2001-05-30 |
BR9912703A (pt) | 2001-05-02 |
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