HUP0102096A2 - Eljárás 1-ciklopropil-5-fenil-pentán-2,4-dion-származékok és intermedierjei előállítására, és az új intermedierek - Google Patents

Eljárás 1-ciklopropil-5-fenil-pentán-2,4-dion-származékok és intermedierjei előállítására, és az új intermedierek

Info

Publication number
HUP0102096A2
HUP0102096A2 HU0102096A HUP0102096A HUP0102096A2 HU P0102096 A2 HUP0102096 A2 HU P0102096A2 HU 0102096 A HU0102096 A HU 0102096A HU P0102096 A HUP0102096 A HU P0102096A HU P0102096 A2 HUP0102096 A2 HU P0102096A2
Authority
HU
Hungary
Prior art keywords
general formula
group
intermediates
compounds
carbon atom
Prior art date
Application number
HU0102096A
Other languages
English (en)
Inventor
Susan Mary Cramp
Neil Jonathan Geach
Original Assignee
Aventis Cropscience S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Cropscience S.A. filed Critical Aventis Cropscience S.A.
Publication of HUP0102096A2 publication Critical patent/HUP0102096A2/hu
Publication of HUP0102096A3 publication Critical patent/HUP0102096A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C23/00—Compounds containing at least one halogen atom bound to a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Press Drives And Press Lines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány szerinti eljárás olyan (I) általános képletű vegyületekelőállítására vonatkozik, ahol R1 és R2 közül az egyik csoportjelentése ciklopropilcsoport, és a másik jelentése két- vagyháromszorosan szubsztituált fenilcsoport, ahol a szubsztituens lehetazonos vagy különböző, és jelentése halogénatom, nitro- vagycianocsoport vagy -(CR4R5)S(O)pR6, -S(O)pR6 általános képletű csoportvagy 1-6 szénatomos alkoxi-, 1-4 szénatomos halogén-alkoxi-, 1-4szénatomos alkil-, 1-4 szénatomos halogén-alkil-, 1,2,4-triazol-1-il-vagy -SF5 csoport, ahol p értéke nulla, egy vagy kettő, R4 és R5jelentése egymástól függetlenül hidrogénatom vagy 1-4 szénatomosalkilcsoport, R6 jelentése 1-4 szénatomos alkilcsoport. Az eljárássorán egy (II) általános képletű vegyületet, ahol R1 és R2 jelentése afenti, és R3 jelentése 1-4 szénatomos alkilcsoport, hidrolizálnak ésdekarboxileznek. A találmány tárgya továbbá az eljárás soránalkalmazott új (II) általános képletű vegyületek és a (II) általánosképletű vegyületeknek és a (III) általános képletű vegyületeknek azelőállítása. Ó
HU0102096A 1998-03-25 1999-03-22 Processes for preparing 1-cyclopropyl-5-phenyl-pentane-2,4-dion derivatives and their intermediates, and the new intermediates HUP0102096A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9806409A GB2335658A (en) 1998-03-25 1998-03-25 Processes for preparing 1-aryl-3-cyclopropyl-propane-1,3-dione intermediates
PCT/EP1999/002335 WO1999048851A2 (en) 1998-03-25 1999-03-22 Processes for preparing intermediates

Publications (2)

Publication Number Publication Date
HUP0102096A2 true HUP0102096A2 (hu) 2002-03-28
HUP0102096A3 HUP0102096A3 (en) 2002-08-28

Family

ID=10829248

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102096A HUP0102096A3 (en) 1998-03-25 1999-03-22 Processes for preparing 1-cyclopropyl-5-phenyl-pentane-2,4-dion derivatives and their intermediates, and the new intermediates

Country Status (21)

Country Link
US (1) US6642418B1 (hu)
EP (1) EP1066237B1 (hu)
JP (1) JP2002507586A (hu)
KR (1) KR100592213B1 (hu)
CN (2) CN1244532C (hu)
AT (1) ATE299851T1 (hu)
AU (1) AU756813B2 (hu)
BR (1) BR9909151A (hu)
CA (1) CA2325402A1 (hu)
DE (1) DE69926223T2 (hu)
GB (1) GB2335658A (hu)
HU (1) HUP0102096A3 (hu)
ID (1) ID27440A (hu)
IL (1) IL138638A0 (hu)
NZ (1) NZ507202A (hu)
PL (1) PL343546A1 (hu)
RU (1) RU2224740C2 (hu)
TR (1) TR200002755T2 (hu)
TW (1) TW593257B (hu)
WO (1) WO1999048851A2 (hu)
ZA (1) ZA200005110B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004029309A1 (de) * 2004-06-17 2005-12-29 Bayer Cropscience Gmbh Pyridinylisoxazole und ihre Verwendung als Herbizide
CN102249921B (zh) * 2010-05-17 2015-09-09 上海升华医药科技有限公司 2-(2,3-二甲基苯基)丙二酸二酯,其制备方法和用途
CN103664564B (zh) * 2012-09-06 2015-09-30 重庆博腾制药科技股份有限公司 一种镇痛药物中间体的制备方法
JPWO2014083935A1 (ja) * 2012-11-27 2017-01-05 株式会社クレハ カルボニル化合物の製造方法
CN104684881A (zh) 2012-11-27 2015-06-03 株式会社吴羽 羰基化合物的制备方法
RU2565789C1 (ru) * 2014-04-08 2015-10-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Нефтехимиии И Катализа Российской Академии Наук Способ получения 2,3-диалкил-1,4-дициклопропил-1,4-бутандионов
CN108623455B (zh) * 2017-03-18 2022-05-31 成都博腾药业有限公司 一种抗心衰药物的中间体

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2395012A (en) * 1943-05-18 1946-02-19 Carbide & Carbon Chem Corp Production of ketones
US4870109A (en) 1985-05-20 1989-09-26 Eli Lilly And Company Control of ectoparasites
US5618547A (en) 1985-05-20 1997-04-08 British Technology Group Limited Control of ectoparasites
US5656573A (en) * 1989-09-11 1997-08-12 Rhone-Poulenc Agriculture Ltd. Herbicidal 4-substituted isoxazoles
GB8920519D0 (en) * 1989-09-11 1989-10-25 Rhone Poulenc Ltd New compositions of matter
IL102674A (en) * 1991-08-05 1996-11-14 Rhone Poulenc Agriculture History of 4-benzoyl isoxazole, the process for their preparation and herbicides containing the same
GB9116834D0 (en) * 1991-08-05 1991-09-18 Rhone Poulenc Agriculture Compositions of new matter
US5532416A (en) 1994-07-20 1996-07-02 Monsanto Company Benzoyl derivatives and synthesis thereof
TR27434A (tr) * 1992-03-12 1995-05-23 Rhone Poulenc Agrochimie Yeni 4-benzoilisoksazol türevleri, bunlari ihtiva eden terkipler ve bunlarin herbisidler olarak kullanilmalari.
JP2792352B2 (ja) * 1992-07-21 1998-09-03 日立工機株式会社 チップソー
MY131387A (en) * 1992-12-18 2007-08-30 Rhone Poulenc Agriculture Novel 4-benzoylisoxazole derivatives, compositions containing them, processes for their preparation, intermediates in their and their use as herbicides
GB9302071D0 (en) * 1993-02-03 1993-03-24 Rhone Poulenc Agriculture Compositions of matter
US5707930A (en) * 1996-09-16 1998-01-13 Zeneca Limited 4-cycloalkyl-5-substituted pyrimidine compounds useful as crop protection agents
US5925795A (en) * 1996-09-16 1999-07-20 Zeneca Limited Processes for the preparation of aryl-β-diketones, arylpyrimidine ketones and crop protection intermediates

Also Published As

Publication number Publication date
ZA200005110B (en) 2001-05-22
IL138638A0 (en) 2001-10-31
GB9806409D0 (en) 1998-05-20
WO1999048851A2 (en) 1999-09-30
DE69926223T2 (de) 2006-04-20
NZ507202A (en) 2003-01-31
AU756813B2 (en) 2003-01-23
CN1163464C (zh) 2004-08-25
RU2224740C2 (ru) 2004-02-27
KR20010042174A (ko) 2001-05-25
ATE299851T1 (de) 2005-08-15
ID27440A (id) 2001-04-12
DE69926223D1 (de) 2005-08-25
BR9909151A (pt) 2007-05-29
CN1301246A (zh) 2001-06-27
EP1066237A2 (en) 2001-01-10
WO1999048851A3 (en) 2000-01-20
PL343546A1 (en) 2001-08-27
CN1244532C (zh) 2006-03-08
TW593257B (en) 2004-06-21
HUP0102096A3 (en) 2002-08-28
KR100592213B1 (ko) 2006-06-23
EP1066237B1 (en) 2005-07-20
CN1554635A (zh) 2004-12-15
CA2325402A1 (en) 1999-09-30
AU3420499A (en) 1999-10-18
US6642418B1 (en) 2003-11-04
TR200002755T2 (tr) 2002-05-21
JP2002507586A (ja) 2002-03-12
GB2335658A (en) 1999-09-29

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