HUP0101739A3 - Extended release tiagabine formulations with reduced side-effects - Google Patents
Extended release tiagabine formulations with reduced side-effectsInfo
- Publication number
- HUP0101739A3 HUP0101739A3 HU0101739A HUP0101739A HUP0101739A3 HU P0101739 A3 HUP0101739 A3 HU P0101739A3 HU 0101739 A HU0101739 A HU 0101739A HU P0101739 A HUP0101739 A HU P0101739A HU P0101739 A3 HUP0101739 A3 HU P0101739A3
- Authority
- HU
- Hungary
- Prior art keywords
- effects
- extended release
- reduced side
- formulations
- release tiagabine
- Prior art date
Links
- 238000013265 extended release Methods 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- PBJUNZJWGZTSKL-MRXNPFEDSA-N tiagabine Chemical compound C1=CSC(C(=CCCN2C[C@@H](CCC2)C(O)=O)C2=C(C=CS2)C)=C1C PBJUNZJWGZTSKL-MRXNPFEDSA-N 0.000 title 1
- 229960001918 tiagabine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7213098P | 1998-01-22 | 1998-01-22 | |
| PCT/US1999/001242 WO1999037302A1 (en) | 1998-01-22 | 1999-01-22 | Extended release tiagabine formulations with reduced side-effects |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0101739A2 HUP0101739A2 (hu) | 2002-03-28 |
| HUP0101739A3 true HUP0101739A3 (en) | 2002-10-28 |
Family
ID=22105780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0101739A HUP0101739A3 (en) | 1998-01-22 | 1999-01-22 | Extended release tiagabine formulations with reduced side-effects |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20070053980A1 (hu) |
| EP (1) | EP1049470B1 (hu) |
| JP (1) | JP2002501022A (hu) |
| KR (1) | KR20010034313A (hu) |
| CN (1) | CN1145484C (hu) |
| AR (1) | AR018041A1 (hu) |
| AT (1) | ATE350035T1 (hu) |
| AU (1) | AU2239599A (hu) |
| BG (1) | BG104692A (hu) |
| CA (1) | CA2318448A1 (hu) |
| CO (1) | CO4970814A1 (hu) |
| DE (1) | DE69934670D1 (hu) |
| HU (1) | HUP0101739A3 (hu) |
| IL (1) | IL137324A0 (hu) |
| NO (1) | NO20003677L (hu) |
| NZ (1) | NZ505725A (hu) |
| PL (1) | PL194595B1 (hu) |
| SA (1) | SA99200204B1 (hu) |
| SK (1) | SK11072000A3 (hu) |
| TR (2) | TR200002102T2 (hu) |
| TW (1) | TW585787B (hu) |
| WO (1) | WO1999037302A1 (hu) |
| ZA (1) | ZA99407B (hu) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6872734B2 (en) | 2000-10-20 | 2005-03-29 | Abbott Laboratories | Use of tiagabine for treatment of diabetic neuropathy and migraine |
| KR100510270B1 (ko) * | 2002-11-29 | 2005-08-26 | 센츄론(주) | 펠렛타이저를 이용한 서방성 제제의 제조방법 |
| CN102908327B (zh) * | 2011-08-05 | 2015-03-11 | 江苏恒瑞医药股份有限公司 | 伊伐布雷定或其可药用盐的缓释制剂 |
| KR102051132B1 (ko) * | 2017-03-17 | 2019-12-02 | 주식회사 종근당 | 미라베그론 또는 이의 염을 포함하는 방출조절용 약제학적 조성물 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5009897A (en) * | 1988-06-24 | 1991-04-23 | Abbott Laboratories | Pharmaceutical granules and tablets made therefrom |
| US5126145A (en) * | 1989-04-13 | 1992-06-30 | Upsher Smith Laboratories Inc | Controlled release tablet containing water soluble medicament |
| US5273758A (en) * | 1991-03-18 | 1993-12-28 | Sandoz Ltd. | Directly compressible polyethylene oxide vehicle for preparing therapeutic dosage forms |
| WO1995005808A1 (en) * | 1993-08-24 | 1995-03-02 | Abbott Laboratories | Oil-based tableting method |
| US5430021A (en) * | 1994-03-18 | 1995-07-04 | Pharmavene, Inc. | Hydrophobic drug delivery systems |
| ZA953078B (en) * | 1994-04-28 | 1996-01-05 | Alza Corp | Effective therapy for epilepsies |
| JP3195360B2 (ja) * | 1995-05-05 | 2001-08-06 | ノボ ノルディスク アクティーゼルスカブ | チアガビン塩酸塩を含有する医薬組成物およびその製法 |
| US5783212A (en) * | 1996-02-02 | 1998-07-21 | Temple University--of the Commonwealth System of Higher Education | Controlled release drug delivery system |
| EP0991409B1 (en) * | 1997-08-01 | 2002-01-30 | ELAN CORPORATION, Plc | Controlled release pharmaceutical compositions containing tiagabine |
| US5843477A (en) * | 1997-09-30 | 1998-12-01 | Bayer Corporation | Lubricants for use in tabletting |
-
1999
- 1999-01-20 ZA ZA9900407A patent/ZA99407B/xx unknown
- 1999-01-21 CO CO99003109A patent/CO4970814A1/es unknown
- 1999-01-22 SK SK1107-2000A patent/SK11072000A3/sk unknown
- 1999-01-22 AU AU22395/99A patent/AU2239599A/en not_active Abandoned
- 1999-01-22 KR KR1020007008031A patent/KR20010034313A/ko not_active IP Right Cessation
- 1999-01-22 TR TR2000/02102T patent/TR200002102T2/xx unknown
- 1999-01-22 CN CNB998040886A patent/CN1145484C/zh not_active Expired - Fee Related
- 1999-01-22 EP EP99902409A patent/EP1049470B1/en not_active Expired - Lifetime
- 1999-01-22 AR ARP990100254A patent/AR018041A1/es unknown
- 1999-01-22 HU HU0101739A patent/HUP0101739A3/hu unknown
- 1999-01-22 CA CA002318448A patent/CA2318448A1/en not_active Abandoned
- 1999-01-22 NZ NZ505725A patent/NZ505725A/xx unknown
- 1999-01-22 TR TR2005/05223T patent/TR200505223T2/xx unknown
- 1999-01-22 DE DE69934670T patent/DE69934670D1/de not_active Expired - Lifetime
- 1999-01-22 PL PL99342767A patent/PL194595B1/pl unknown
- 1999-01-22 WO PCT/US1999/001242 patent/WO1999037302A1/en not_active Application Discontinuation
- 1999-01-22 IL IL13732499A patent/IL137324A0/xx unknown
- 1999-01-22 AT AT99902409T patent/ATE350035T1/de not_active IP Right Cessation
- 1999-01-22 JP JP2000528284A patent/JP2002501022A/ja not_active Withdrawn
- 1999-03-16 TW TW088100990A patent/TW585787B/zh not_active IP Right Cessation
- 1999-06-01 SA SA99200204A patent/SA99200204B1/ar unknown
-
2000
- 2000-07-18 NO NO20003677A patent/NO20003677L/no not_active Application Discontinuation
- 2000-08-15 BG BG104692A patent/BG104692A/xx unknown
-
2006
- 2006-11-03 US US11/592,694 patent/US20070053980A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CO4970814A1 (es) | 2000-11-07 |
| NZ505725A (en) | 2003-01-31 |
| CA2318448A1 (en) | 1999-07-29 |
| NO20003677L (no) | 2000-09-20 |
| ATE350035T1 (de) | 2007-01-15 |
| EP1049470B1 (en) | 2007-01-03 |
| KR20010034313A (ko) | 2001-04-25 |
| TR200002102T2 (tr) | 2000-12-21 |
| HUP0101739A2 (hu) | 2002-03-28 |
| AU2239599A (en) | 1999-08-09 |
| PL342767A1 (en) | 2001-07-02 |
| BG104692A (en) | 2001-05-31 |
| CN1293571A (zh) | 2001-05-02 |
| ZA99407B (en) | 1999-07-20 |
| EP1049470A1 (en) | 2000-11-08 |
| SA99200204B1 (ar) | 2006-10-11 |
| DE69934670D1 (de) | 2007-02-15 |
| AR018041A1 (es) | 2001-10-31 |
| US20070053980A1 (en) | 2007-03-08 |
| TR200505223T2 (tr) | 2006-04-21 |
| JP2002501022A (ja) | 2002-01-15 |
| TW585787B (en) | 2004-05-01 |
| WO1999037302A1 (en) | 1999-07-29 |
| NO20003677D0 (no) | 2000-07-18 |
| PL194595B1 (pl) | 2007-06-29 |
| CN1145484C (zh) | 2004-04-14 |
| SK11072000A3 (sk) | 2001-01-18 |
| IL137324A0 (en) | 2001-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |