HUP0101614A2 - Biotin-kötő receptor molekulák - Google Patents
Biotin-kötő receptor molekulákInfo
- Publication number
- HUP0101614A2 HUP0101614A2 HU0101614A HUP0101614A HUP0101614A2 HU P0101614 A2 HUP0101614 A2 HU P0101614A2 HU 0101614 A HU0101614 A HU 0101614A HU P0101614 A HUP0101614 A HU P0101614A HU P0101614 A2 HUP0101614 A2 HU P0101614A2
- Authority
- HU
- Hungary
- Prior art keywords
- biotin
- receptor molecules
- binding receptor
- subject
- target site
- Prior art date
Links
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 title abstract 4
- 230000027455 binding Effects 0.000 title abstract 2
- 229960002685 biotin Drugs 0.000 title abstract 2
- 235000020958 biotin Nutrition 0.000 title abstract 2
- 239000011616 biotin Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A találmány tárgya membrán-feszítő domént és exracelluláris doménttartalmazó fehérje, melyben az extracelluláris domén biotinkötőaktivitást tartalmaz. A találmány tárgyához tartozik továbbá amegfelelő fehérje-előállítási eljárás, valamint a biotinilezettmolekula alkalmazása a célhelyre bejuttatható gyógyszer előállítására,mely célhely az 1-5. igénypontok bármelyike szerinti fehérjéttartalmazza. Ó
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9803757.5A GB9803757D0 (en) | 1998-02-23 | 1998-02-23 | Fusion proteins |
GBGB9813653.4A GB9813653D0 (en) | 1998-06-24 | 1998-06-24 | Fusion proteins |
PCT/GB1999/000546 WO1999042577A2 (en) | 1998-02-23 | 1999-02-23 | Biotin-binding receptor molecules |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0101614A2 true HUP0101614A2 (hu) | 2001-09-28 |
HUP0101614A3 HUP0101614A3 (en) | 2006-04-28 |
Family
ID=26313170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0101614A HUP0101614A3 (en) | 1998-02-23 | 1999-02-23 | Biotin-binding receptor molecules |
Country Status (16)
Country | Link |
---|---|
US (1) | US7208291B2 (hu) |
EP (1) | EP1056850B1 (hu) |
JP (1) | JP2002504328A (hu) |
KR (1) | KR100722578B1 (hu) |
CN (1) | CN1195852C (hu) |
AT (1) | ATE274058T1 (hu) |
AU (1) | AU750444B2 (hu) |
CA (1) | CA2319039A1 (hu) |
DE (1) | DE69919515T2 (hu) |
DK (1) | DK1056850T3 (hu) |
ES (1) | ES2226340T3 (hu) |
HU (1) | HUP0101614A3 (hu) |
NO (1) | NO328139B1 (hu) |
PL (1) | PL195990B1 (hu) |
PT (1) | PT1056850E (hu) |
WO (1) | WO1999042577A2 (hu) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040209294A1 (en) * | 2002-09-02 | 2004-10-21 | National Food Research Institute | Method to produce a receptor chip using biotinylated protein |
US9623117B2 (en) * | 2011-04-04 | 2017-04-18 | Wisconsin Alumni Research Foundation | Method for selective targeting and entry of bacterial toxins to cells |
SG10201804439PA (en) * | 2013-12-20 | 2018-06-28 | Hutchinson Fred Cancer Res | Tagged chimeric effector molecules and receptors thereof |
EP3288570A4 (en) | 2015-04-29 | 2018-11-21 | Fred Hutchinson Cancer Research Center | Modified stem cells and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4839293A (en) * | 1986-02-24 | 1989-06-13 | The Trustees Of Columbia University In The City Of New York | DNA encoding streptavidin, streptavidin produced therefrom, fused polypeptides which include amino acid sequences present in streptavidin and uses thereof |
US5135736A (en) * | 1988-08-15 | 1992-08-04 | Neorx Corporation | Covalently-linked complexes and methods for enhanced cytotoxicity and imaging |
CA1340977C (en) * | 1988-11-15 | 2000-04-25 | Monty Krieger | Scavenger receptor protein and antibody thereto |
US5457035A (en) * | 1993-07-23 | 1995-10-10 | Immunex Corporation | Cytokine which is a ligand for OX40 |
US5846537A (en) | 1995-06-07 | 1998-12-08 | University Of Rochester | Modified avidin and streptavidin and methods of use thereof |
US6497881B1 (en) * | 1995-11-30 | 2002-12-24 | New York University | High efficiency tissue specific compound delivery system using streptavidin-protein a fusion protein |
-
1999
- 1999-02-23 PT PT99906341T patent/PT1056850E/pt unknown
- 1999-02-23 CA CA002319039A patent/CA2319039A1/en not_active Abandoned
- 1999-02-23 AU AU26312/99A patent/AU750444B2/en not_active Ceased
- 1999-02-23 JP JP2000532517A patent/JP2002504328A/ja active Pending
- 1999-02-23 DK DK99906341T patent/DK1056850T3/da active
- 1999-02-23 WO PCT/GB1999/000546 patent/WO1999042577A2/en active IP Right Grant
- 1999-02-23 PL PL99343079A patent/PL195990B1/pl not_active IP Right Cessation
- 1999-02-23 KR KR1020007009270A patent/KR100722578B1/ko not_active IP Right Cessation
- 1999-02-23 EP EP99906341A patent/EP1056850B1/en not_active Expired - Lifetime
- 1999-02-23 AT AT99906341T patent/ATE274058T1/de not_active IP Right Cessation
- 1999-02-23 DE DE69919515T patent/DE69919515T2/de not_active Expired - Lifetime
- 1999-02-23 ES ES99906341T patent/ES2226340T3/es not_active Expired - Lifetime
- 1999-02-23 HU HU0101614A patent/HUP0101614A3/hu not_active Application Discontinuation
- 1999-02-23 CN CNB998032174A patent/CN1195852C/zh not_active Expired - Fee Related
-
2000
- 2000-08-22 NO NO20004195A patent/NO328139B1/no not_active IP Right Cessation
-
2003
- 2003-07-11 US US10/618,570 patent/US7208291B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69919515T2 (de) | 2005-04-07 |
HUP0101614A3 (en) | 2006-04-28 |
PL195990B1 (pl) | 2007-11-30 |
JP2002504328A (ja) | 2002-02-12 |
CN1195852C (zh) | 2005-04-06 |
KR20010085196A (ko) | 2001-09-07 |
EP1056850A2 (en) | 2000-12-06 |
EP1056850B1 (en) | 2004-08-18 |
CN1291230A (zh) | 2001-04-11 |
DK1056850T3 (da) | 2004-11-29 |
AU750444B2 (en) | 2002-07-18 |
US20040185059A1 (en) | 2004-09-23 |
PL343079A1 (en) | 2001-07-30 |
NO20004195L (no) | 2000-08-22 |
AU2631299A (en) | 1999-09-06 |
NO328139B1 (no) | 2009-12-14 |
WO1999042577A3 (en) | 1999-10-21 |
CA2319039A1 (en) | 1999-08-26 |
ATE274058T1 (de) | 2004-09-15 |
KR100722578B1 (ko) | 2007-05-28 |
PT1056850E (pt) | 2004-12-31 |
DE69919515D1 (de) | 2004-09-23 |
ES2226340T3 (es) | 2005-03-16 |
NO20004195D0 (no) | 2000-08-22 |
WO1999042577A2 (en) | 1999-08-26 |
US7208291B2 (en) | 2007-04-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC9A | Change of name, address |
Owner name: ARK THERAPEUTICS LIMITED, GB Free format text: FORMER OWNER(S): EUROGENE LIMITED, GB |
|
FC4A | Lapse of provisional application due to refusal |