HUP0101278A2 - Növényi riboflavin bioszintézis gének és alkalmazásuk - Google Patents

Növényi riboflavin bioszintézis gének és alkalmazásuk

Info

Publication number
HUP0101278A2
HUP0101278A2 HU0101278A HUP0101278A HUP0101278A2 HU P0101278 A2 HUP0101278 A2 HU P0101278A2 HU 0101278 A HU0101278 A HU 0101278A HU P0101278 A HUP0101278 A HU P0101278A HU P0101278 A2 HUP0101278 A2 HU P0101278A2
Authority
HU
Hungary
Prior art keywords
plant
biosynthesis genes
plants
riboflavin
synthase
Prior art date
Application number
HU0101278A
Other languages
English (en)
Inventor
Sandra Alice Brunn
Charles David Guyer
Marie Ann Johnson
Sandra Lynn Volrath
Eric Russell Ward
Original Assignee
Novartis Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag. filed Critical Novartis Ag.
Publication of HUP0101278A2 publication Critical patent/HUP0101278A2/hu
Publication of HUP0101278A3 publication Critical patent/HUP0101278A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A találmány tárgyát a növényi riboflavin szintáz enzim komplex(lumazin szintáz) < alegységét kódoló gént és a kétfunkciósciklohidroláz II/DHBP szintázt kódoló gént tartalmazó növényiriboflavin bioszintézis gének képezik. A találmány továbbá e növényiriboflavin bioszintézis enzimek heterológ gazdákban történőrekombináns előállítására, a rekombinánsan előállított enzimekfelhasználásával herbicid aktivitással rendelkező vegyületekkeresésére és az így azonosított herbicid vegyületek nem kívántnövényzet növekedésének elnyomására történő alkalmazására vonatkozik.Ezenkívül, a találmány eljárásokat biztosít herbicid toleranciakifejlesztésére növényekben, növényi szövetekben, növényi magvakban ésnövényi sejtekben a találmány szerinti riboflavin bioszintézis génekfelhasználásával. Ó
HU0101278A 1998-01-30 1999-01-28 Riboflavin biosynthesis genes from plants and uses thereof HUP0101278A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10981098P 1998-01-30 1998-01-30
PCT/EP1999/000556 WO1999038986A2 (en) 1998-01-30 1999-01-28 Riboflavin biosynthesis genes from plants and uses thereof

Publications (2)

Publication Number Publication Date
HUP0101278A2 true HUP0101278A2 (hu) 2001-08-28
HUP0101278A3 HUP0101278A3 (en) 2003-04-28

Family

ID=22329685

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101278A HUP0101278A3 (en) 1998-01-30 1999-01-28 Riboflavin biosynthesis genes from plants and uses thereof

Country Status (17)

Country Link
EP (1) EP1051504A2 (hu)
JP (1) JP2002501753A (hu)
KR (1) KR20010082509A (hu)
CN (1) CN1289369A (hu)
AU (1) AU744487B2 (hu)
BR (1) BR9908213A (hu)
CA (1) CA2318522A1 (hu)
CZ (1) CZ20002750A3 (hu)
HU (1) HUP0101278A3 (hu)
ID (1) ID25910A (hu)
IL (1) IL137303A0 (hu)
IN (1) IN2000CH00209A (hu)
MX (1) MXPA00007432A (hu)
PL (1) PL342805A1 (hu)
TR (1) TR200002193T2 (hu)
WO (1) WO1999038986A2 (hu)
ZA (1) ZA99716B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010083077A (ko) * 1998-08-12 2001-08-31 추후제출 제초제 선택성 작물을 생성하는 ｄｎａ 재편성
JP2002534094A (ja) * 1998-12-15 2002-10-15 バッハー，アーデルバート リボフラビン生合成の阻害剤のためのスクリーニング方法
DE19910102B4 (de) * 1999-03-08 2006-06-01 Fischer, Markus, Dr.rer.nat. Proteinkonjugate, Verfahren, Vektoren, Proteine und DNA zu deren Herstellung, deren Verwendung, sowie Arzneimittel und Impfstoffe mit einem Gehalt derselben
DE19942175A1 (de) * 1999-09-03 2001-03-08 Adelbert Bacher Methode zum Auffinden von Inhibitoren der Riboflavinbiosynthese
AU2001248371A1 (en) * 2000-04-18 2001-10-30 Syngenta Participations Ag Amino acid:glyoxylate aminotransferase genes from plants and uses thereof
CN110964769B (zh) * 2019-11-29 2022-11-11 河南巨龙生物工程股份有限公司 一种提高枯草芽孢杆菌发酵生产核黄素收率的方法

Also Published As

Publication number Publication date
BR9908213A (pt) 2000-11-28
IL137303A0 (en) 2001-07-24
AU744487B2 (en) 2002-02-28
IN2000CH00209A (hu) 2005-05-20
CN1289369A (zh) 2001-03-28
MXPA00007432A (en) 2001-02-01
PL342805A1 (en) 2001-07-02
KR20010082509A (ko) 2001-08-30
WO1999038986A3 (en) 1999-09-23
AU2720299A (en) 1999-08-16
CZ20002750A3 (cs) 2000-11-15
ID25910A (id) 2000-11-09
EP1051504A2 (en) 2000-11-15
JP2002501753A (ja) 2002-01-22
WO1999038986A2 (en) 1999-08-05
HUP0101278A3 (en) 2003-04-28
ZA99716B (en) 1999-07-30
CA2318522A1 (en) 1999-08-05
TR200002193T2 (tr) 2001-05-21

Similar Documents

Publication Publication Date Title
HK1038590A1 (en) Methods and means to modulate programmed cell death in eukaryotic cells
DE60036477D1 (en) Isoprenoid biosynthese
EP2103688A3 (en) Method for modifying plant morphology, biochemistry and physiology
DK1244348T3 (da) Hybridvinter-oliefröraps samt fremgangsmåder til dens fremstilling
WO2002023974A1 (fr) Plante ayant une meilleure tolerance a diverses contraintes environnementales, procede de production de cette plante et gene d&#39;enzyme relatif au metabolisme de la polyamine
WO2000042205A3 (en) Herbicide target gene and methods
EP1212438B8 (en) Flax seed specific promoters
HUP0101278A2 (hu) Növényi riboflavin bioszintézis gének és alkalmazásuk
WO1999029880A3 (de) Verfahren zur herstellung transgener pflanzen mit veränderter 5-aminolävulinsäure-biosynthese und verfahren zur identifizierung von effektoren der 5-aminolävulinsäure-synthese
WO2001002020A3 (en) Compositions and methods for targeted enzymatic release of cell regulatory compounds
FR2795424B1 (fr) Promoteur s&#39;exprimant specifiquement dans les cellules de racines de plantes, vecteurs et cellules hotes recombinantes comprenant un tel promoteur et plantes transgeniques obtenues
AU2003217458A1 (en) Expression of lysosomal enzymes in plant seeds
WO2000015809A3 (en) Uracil permease from arabidopsis as herbicidal target gene
WO2000077185A3 (en) Herbicide target genes and methods
DK0416572T3 (da) RNA med endoribonucleasevirkning mod mRNA fra modningsgener, dens fremstilling af den anvendelse i planter
WO2000022145A3 (en) A hydroperoxide lyase gene from maize and methods of use
WO2000053782A3 (en) Herbicide target genes and methods
MXPA03007469A (es) Manipulacion de genes sucrosa sintasa para mejorar la calidad del grano y tallo.
AUPQ815500A0 (en) Modification of fructan biosynthesis
WO2001079514A3 (en) Amino acid:glyoxylate aminotransferase genes from plants and uses thereof
EP1209227A3 (en) Cytochrome P450 hydroxylase, an important enzyme in brassinosteroid biosynthesis of plants
US20160108414A1 (en) Growth-related enox proteins from plants with yield enhancement potential, sequences and methods
WO2000000598A3 (en) Plant dwarfing
WO2001044277A3 (en) Herbicide target genes and methods
WO2002000696A3 (en) Herbicide target genes and methods