WO2000042205A3 - Herbicide target gene and methods - Google Patents

Herbicide target gene and methods Download PDF

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Publication number
WO2000042205A3
WO2000042205A3 PCT/EP2000/000246 EP0000246W WO0042205A3 WO 2000042205 A3 WO2000042205 A3 WO 2000042205A3 EP 0000246 W EP0000246 W EP 0000246W WO 0042205 A3 WO0042205 A3 WO 0042205A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
target gene
development
herbicide target
plant
Prior art date
Application number
PCT/EP2000/000246
Other languages
French (fr)
Other versions
WO2000042205A2 (en
Inventor
Joshua Zvi Levin
Gregory Joseph Budziszewski
Sharon Lee Potter
Lynette Marcia Wegrich
Original Assignee
Novartis Ag
Novartis Erfind Verwalt Gmbh
Joshua Zvi Levin
Gregory Joseph Budziszewski
Sharon Lee Potter
Lynette Marcia Wegrich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Novartis Erfind Verwalt Gmbh, Joshua Zvi Levin, Gregory Joseph Budziszewski, Sharon Lee Potter, Lynette Marcia Wegrich filed Critical Novartis Ag
Priority to AU22909/00A priority Critical patent/AU2290900A/en
Priority to CA002362484A priority patent/CA2362484A1/en
Priority to EP00901557A priority patent/EP1141344A2/en
Priority to JP2000593762A priority patent/JP2002534128A/en
Publication of WO2000042205A2 publication Critical patent/WO2000042205A2/en
Publication of WO2000042205A3 publication Critical patent/WO2000042205A3/en
Priority to HK02101120.9A priority patent/HK1041287A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance

Abstract

The invention relates to genes isolated from Arabidopsis that code for proteins essential for seedling growth. The invention also includes the methods of using these proteins to discover new herbicides, based on the essentiality of the genes for normal growth and development. The invention can also be used in a screening assay to identify inhibitors that are potential herbicides. The invention is also applied to the development of herbicide tolerant plants, plant tissues, plant seeds, and plant cells.
PCT/EP2000/000246 1999-01-15 2000-01-13 Herbicide target gene and methods WO2000042205A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU22909/00A AU2290900A (en) 1999-01-15 2000-01-13 Herbicide target gene and methods
CA002362484A CA2362484A1 (en) 1999-01-15 2000-01-13 Herbicide target gene and methods
EP00901557A EP1141344A2 (en) 1999-01-15 2000-01-13 Herbicide target gene and methods
JP2000593762A JP2002534128A (en) 1999-01-15 2000-01-13 Genes targeted by herbicides and methods for targeting the genes
HK02101120.9A HK1041287A1 (en) 1999-01-15 2002-02-15 Herbicide target gene and methods

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US23276099A 1999-01-15 1999-01-15
US09/232,760 1999-01-15
US23747999A 1999-01-26 1999-01-26
US09/237,479 1999-01-26
US24428899A 1999-02-03 1999-02-03
US09/244,288 1999-02-03
US25233699A 1999-02-18 1999-02-18
US09/252,336 1999-02-18
US28137699A 1999-03-30 1999-03-30
US09/281,376 1999-03-30

Publications (2)

Publication Number Publication Date
WO2000042205A2 WO2000042205A2 (en) 2000-07-20
WO2000042205A3 true WO2000042205A3 (en) 2000-12-07

Family

ID=27540005

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/000246 WO2000042205A2 (en) 1999-01-15 2000-01-13 Herbicide target gene and methods

Country Status (7)

Country Link
EP (1) EP1141344A2 (en)
JP (1) JP2002534128A (en)
CN (1) CN1341151A (en)
AU (1) AU2290900A (en)
CA (1) CA2362484A1 (en)
HK (1) HK1041287A1 (en)
WO (1) WO2000042205A2 (en)

Families Citing this family (21)

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AU3169999A (en) 1998-04-14 1999-11-01 Kyowa Hakko Kogyo Co. Ltd. Process for producing isoprenoid compounds by using microorganisms and method for detecting compounds having antibacterial or herbicidal activity
PT1190068E (en) 1999-04-15 2006-06-30 Calgene Llc SEQUENCES OF NUCLEIC ACIDS FOR PROTEINS INVOLVED IN TOCOFEROL SYNTHESIS
DE19918949A1 (en) * 1999-04-27 2000-11-23 Basf Ag Overexpression of a DNA sequence coding for a 1-deoxy-D-xylulose-5-phosphate reductoisomerase in plants
EP1204756A2 (en) * 1999-07-30 2002-05-15 Bayer Aktiengesellschaft Method of determining the activity of 1-deoxy-d-xylulose-5-phosphate reductoisomerase and 1-deoxy-d-xylulose-5-phosphate synthase
US6872815B1 (en) 2000-10-14 2005-03-29 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
US6646182B2 (en) 2000-04-19 2003-11-11 Pioneer Hi-Bred International, Inc. Mre11 orthologue and uses thereof
EP1335979A2 (en) * 2000-08-03 2003-08-20 Syngenta Participations AG Herbicide target genes and methods
ATE447017T1 (en) 2000-08-07 2009-11-15 Monsanto Technology Llc GENES INVOLVED IN THE METHYL-D-ERYTHRIOL PHOSPHATE PATHWAY
EP1217074A1 (en) * 2000-12-22 2002-06-26 Universiteit Leiden Nucleic acid integration in eukaryotes
WO2002064794A2 (en) * 2001-01-11 2002-08-22 Syngenta Participations Ag Herbicide target genes and methods
US7161061B2 (en) 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
WO2002089561A1 (en) 2001-05-09 2002-11-14 Monsanto Technology Llc. Tyra genes and uses thereof
AU2002328909A1 (en) * 2001-07-16 2003-03-03 Syngenta Participations Ag Nucleic acid molecules encoding proteins essential for plant growth
WO2003016482A2 (en) 2001-08-17 2003-02-27 Monsanto Technology Llc Methyltransferase genes and uses thereof
US7262339B2 (en) 2001-10-25 2007-08-28 Monsanto Technology Llc Tocopherol methyltransferase tMT2 and uses thereof
BRPI0308740B1 (en) 2002-03-19 2018-11-21 Monsanto Technology Llc nucleic acid molecule encoding a homogenous prenyl transferase (“hpt”) and method of producing plant having increased tocopherol level seed
AU2003221498A1 (en) * 2002-03-20 2003-09-29 Basf Aktiengesellschaft Serine hydroxymethyltransferase as a target for herbicides
US7230165B2 (en) 2002-08-05 2007-06-12 Monsanto Technology Llc Tocopherol biosynthesis related genes and uses thereof
DE10238434A1 (en) * 2002-08-16 2004-04-15 Metanomics Gmbh & Co. Kgaa Process for the identification of substances with herbicidal activity
GB2392444A (en) * 2002-08-29 2004-03-03 Syngenta Participations Ag Nucleic acid molecules encoding proteins essential for plant growth and development and uses thereof
US9612235B2 (en) * 2012-04-05 2017-04-04 Koch Biological Solutions, Llc Herbicidal compound screening

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154204A2 (en) * 1984-03-06 1985-09-11 Mgi Pharma, Inc. Herbicide resistance in plants
US5013659A (en) * 1987-07-27 1991-05-07 E. I. Du Pont De Nemours And Company Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase
US5162602A (en) * 1988-11-10 1992-11-10 Regents Of The University Of Minnesota Corn plants tolerant to sethoxydim and haloxyfop herbicides
WO2000015809A2 (en) * 1998-09-15 2000-03-23 Syngenta Participations Ag Uracil permease from arabidopsis as herbicidal target gene

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154204A2 (en) * 1984-03-06 1985-09-11 Mgi Pharma, Inc. Herbicide resistance in plants
US5013659A (en) * 1987-07-27 1991-05-07 E. I. Du Pont De Nemours And Company Nucleic acid fragment encoding herbicide resistant plant acetolactate synthase
US5162602A (en) * 1988-11-10 1992-11-10 Regents Of The University Of Minnesota Corn plants tolerant to sethoxydim and haloxyfop herbicides
WO2000015809A2 (en) * 1998-09-15 2000-03-23 Syngenta Participations Ag Uracil permease from arabidopsis as herbicidal target gene

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
AZPIROZ-LEEHAN R ET AL: "T-DNA insertion mutagenesis in Arabidopsis: going back and forth", TRENDS IN GENETICS,NL,ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, vol. 13, no. 4, 1 April 1997 (1997-04-01), pages 152 - 156, XP004056902, ISSN: 0168-9525 *
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, 1 April 1998 (1998-04-01), HINXTON, GB, XP002140499 *
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, 1 December 1992 (1992-12-01), HINXTON, GB, XP002140497 *
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, 1 February 1997 (1997-02-01), HINXTON, GB, XP002140500 *
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, 1 November 1997 (1997-11-01), HINXTON, GB, XP002140498 *
DATABASE EMBL NUCLEOTIDE AND PROTEIN SEQUENCES, 13 October 1997 (1997-10-13), HINXTON, GB, XP002140496 *
FELDMANN K A ET AL: "A DWARF MUTANT OF ARABIDOPSIS GENERATED BY T-DNA INSERTION MUTAGENESIS", SCIENCE,US,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, vol. 243, 10 March 1989 (1989-03-10), pages 1351 - 1354, XP002036944, ISSN: 0036-8075 *
ITO KOICHI ET AL: "Single amino acid substitution in prokaryote polypeptide release factor 2 permits it to terminate translation at all three stop codons.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA JULY 7, 1998, vol. 95, no. 14, 7 July 1998 (1998-07-07), pages 8165 - 8169, XP002140501, ISSN: 0027-8424 *
KONCZ ET AL: "isolation of a gene encoding a novel chloroplast protein by T-DNA tagging in Arabidopsis thaliana", EMBO JOURNAL,GB,OXFORD UNIVERSITY PRESS, SURREY, vol. 5, no. 9, 1 January 1990 (1990-01-01), pages 1337 - 1346, XP002076478, ISSN: 0261-4189 *
TOPPING JENNIFER F ET AL: "Mutations in the HYDRA1 gene of Arabidoposis perturb cell shape and disrupt embryonic and seedling morphogenesis.", DEVELOPMENT (CAMBRIDGE) NOV., 1997, vol. 124, no. 21, November 1997 (1997-11-01), pages 4415 - 4424, XP000920674, ISSN: 0950-1991 *
ZHOU D -X ET AL: "COP1b, an isoform of COP1 generated by alternative splicing, has a negative effect on COP1 function in regulating light-dependent seedling development in Arabidopsis.", MOLECULAR & GENERAL GENETICS FEB., 1998, vol. 257, no. 4, February 1998 (1998-02-01), pages 387 - 391, XP000920653, ISSN: 0026-8925 *

Also Published As

Publication number Publication date
AU2290900A (en) 2000-08-01
JP2002534128A (en) 2002-10-15
HK1041287A1 (en) 2002-07-05
CN1341151A (en) 2002-03-20
WO2000042205A2 (en) 2000-07-20
CA2362484A1 (en) 2000-07-20
EP1141344A2 (en) 2001-10-10

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