GB2392444A - Nucleic acid molecules encoding proteins essential for plant growth and development and uses thereof - Google Patents

Abstract

Nucleotide sequences are isolated from Arabidopsis thaliana that code for proteins essential for plant growth and development. The essentially of the proteins may be exploited by recombinantly expressing the proteins and using them in screening assays to identify compounds that interact with or inhibit the proteins and are therefore potential herbicides.

Description

GB 2392444 A continuation (74) Agent and/or Address for Service: Jozsef

Christopher Gaal Syngenta Limited, PO Box 3538, Intellectual Property Department, Jealotts Hill Research Centre, BRACKNELL, Berks, RG42 6YA, United Kingdom

NUCLEIC ACID MOLECULES ENCODING PROTEINS ESSENTIAL FOR

PLANT GROWTH AND DEVELOPMENT AND USES THEREOF

FIELD OF THE INVENTION

The present invention pertains to nucleic acid molecules isolated from Arabidopsis thaliana compri sing nucleotide sequences that encode proteins essential for plant growth and de.v-lopment. The invention particularly relates to methods of using - These proteins as herbicide targets, based on this essentiality.

lo. BACKGROUND OF THE INVENTION

The use of herbicides to control undesirable vegetation such as weeds in crop fields has become almost a universal practice. The herbicide market exceeds 15 billion

5 dollars annually. Despite this extensive use, weed control remains a significant and costly problem for farmers.

Effective use of herbicides requires sound management. For instance, the time and method of application and stage of weed plant development are critical to achieving good weed control with herbicides. Because various weed species are resistant to 20 herbicides, the production of effective new herbicides becomes increasingly important.

New herbicides can now be discovered using high-throughput screens that implement recombinant DNA technology. Metabolic enzymes found to be essential to plant growth and development can be recombinantly produced through standard molecular biological techniques and utilized as herbicide targets in screens for novel inhibitors of the enzyme 25 activity. More generally, any essential plant protein can be used to screen for inhibitors of its activity. The novel inhibitors discovered through such screens may then be used as herbicides to control undesirable vegetation.

In view of the above, there remain persistent and ongoing problems with unwanted or detrimental vegetation growth (e.g. weeds).:t urthermore, as the population 30 continues to grow, there will be increasing food shortages. Therefore, there exists a long felt, yet unfulfilled need, to find new, effective, and economic herbicides.

- 2 SUMMARY OF THE INVENTION

In view ofthese needs, it is an object ofthe invention to provide nucleic acid molecules from Arabidopsis thaliana comprising nucleotide sequences that encode 5 proteins essential for plant growth and development. It is another object to provide the essential proteins encoded by these essential nucleotide sequences for assay development to identify inhibitory compounds with herbicidal activity. It is still another object of the present invention to provide an effective and beneficial method for identifying new or improved herbicides using the essential proteins of the invention.

0 In furtherance of these and other objects, the present invention provides nucleic acid molecules isolated from Arabidopsis thaliana comprising nucleotide sequences that encode proteins essential for plant viability. Genetic results show that when any of the nucleotide sequences of the invention are mutated in Arabidopsis thaliana, the resulting phenotype is embryo or seedling lethal in the homozygous state. In particular, by using 5 AclDs transposon or T-DNA-mediated mutagenesis, the inventors of the present invention are the first to demonstrate that the activity of each protein of the present invention is essential for plant growth in Arabidopsis thaliana.

This knowledge is exploited to provide novel herbicide modes of action. The critical role in plant growth of the proteins encoded by each of the nucleotide sequences 20 of the invention implies that chemicals that inhibit the function of any one of these proteins in plants are likely to have detrimental effects on plants and are potentially good herbicide candidates. Thus, the proteins encoded by the essential nucleotide sequences provide the bases for assays designed to easily and rapidly identify novel herbicides.

The present invention therefore provides methods of using a purified protein Is encoded by any one of the nucleotide sequences described below to identify inhibitors thereof, which can then be used as herbicides to suppress the growth of undesirable vegetation, e.g in fields where crops are grown, particularly agronomically important

crops such as maize and other cereal crops such as wheat, oats, rye, sorghum, rice, barley, millet, turf and forage grasses, and the like, as well as cotton, sugar cane, sugar 30 beet, oilseed rape, and soybeans.

Disclosed herein are nucleic acid molecules isolated from Arabidopsis thaliana.

In one embodiment, the present invention provides an isolated nucleic acid molecule comprising a nucleotide sequence, the complement of which hybridizes under stringent

conditions to a sequence selected from the group consisting of the odd numbered SEQ ID NOs: 1-93. In another embodiment, the present invention provides an isolated nucleic acid molecule comprising a nucleotide sequence that encodes a protein comprising an amino acid sequence having at least 60%, preferably 70%, more preferably 80%, still s more preferably 90%, even more preferably 95%, and most preferably 99-100% sequence identity to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94.

The present invention also provides a chimeric construct comprising a promoter operatively linked to a nucleic acid molecule according to the present invention, wherein lo the promoter is preferably functional in a eukaryote, wherein the promoter is preferably heterologous to the nucleic acid molecule. The present invention further provides a recombinant vector comprising a chimeric construct according to the present invention, wherein said vector is capable of being stably transformed into a host cell. The present invention still further provides a host cell comprising a nucleic acid molecule according 5 to the present invention, wherein said nucleic acid molecule is preferably expressible in the cell. The host cell is preferably selected from the group consisting of a plant cell, a yeast cell, an insect cell, and a prokaryotic cell. The present invention additionally provides a plant or seed comprising a plant cell according to the present invention.

The present invention also provides proteins essential for plant growth in 20 Arabidopsis thaliana. In one embodiment, the present invention provides an isolated protein comprising an amino acid sequence having at least 60%, preferably 70%, more preferably 80%, still more preferably 90%, even more preferably 95%, and most preferably 99-100% sequence identity to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94. In accordance with another 2s embodiment, the present invention also relates to the recombinant production of proteins of the invention and methods of using the proteins of the invention in assays for identifying compounds that interact with the protein.

According to another aspect, the present invention provides a method of identifying a herbicidal compound, comprising: (a) combining a polypeptide comprising 30 an amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94 with a compound to be tested for the ability to bind to said polypeptide, under conditions conducive to binding; (b) selecting a compound identified in (a) that binds to said polypeptide; (c) applying a

-4 compound selected in (b) to a plant to test for herbicidal activity; and (d) selecting a compound identified in (c) that has herbicidal activity. Preferably, the polypeptide comprises an amino acid sequence at least 95% identical to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94. More s preferably, the polypeptide comprises an amino acid sequence at least 99% identical to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94. Most preferably, the polypeptide comprises an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94. The present invention also provides a method for killing or inhibiting the growth or viability of a lo plant, comprising applying to the plant a herbicidal compound identified according to this method. According to yet another aspect, the present invention provides a method of identifying a herbicidal compound, comprising: (a) combining a polypeptide comprising an amino acid sequence at least 90% identical to an amino acid sequence selected from 5 the group consisting of the even numbered SEQ ID NOs:2-94 with a compound to be tested for the ability to inhibit the activity of said polypeptide, under conditions conducive to inhibition; (b) selecting a compound identified in (a) that inhibits the activity of said polypeptide; (c) applying a compound selected in (b) to a plant to test for herbicidal activity; and (d) selecting a compound identified in (c) that has herbicidal 20 activity. Preferably, the polypeptide comprises an amino acid sequence at least 95% identical to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94. More preferably, the polypeptide comprises an amino acid sequence at least 99% identical to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94. Most preferably, the polypeptide 25 comprises an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94. The present invention also provides a method for killing or inhibiting the growth or viability of a plant, comprising applying to the plant a herbicidal compound identified according to this method.

The present invention still further provides a method for killing or inhibiting the 30 growth or viability of a plant, comprising inhibiting expression in said plant of a protein having at least 60%, preferably 70%, more preferably 80%, still more preferably 90%, even more preferably 95%, and most preferably 99-100% sequence identity to an amino

- s - acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-

94. Other objects and advantages of the present invention will become apparent to those skilled in the art and from a study of the following description of the invention and

s non-limiting examples. The entire contents of all publications mentioned herein are hereby incorporated by reference.

BRIEF DESCRIPTION OF THE SEQUENCES IN THE SEQUENCE LISTING

0 Odd numbered SEQ ID NOs:1-93 are nucleotide sequences isolated from Arabidopsis thaliana that are more fully described in Table 5 below.

Even numbered SEQ ID NOs:2-94 are protein sequences encoded by the immediately preceding nucleotide sequence, e.g. SEQ ID NO:2 is the protein encoded by the nucleotide sequence of SEQ ID NO: 1, SEQ ID NO:4 is the protein encoded by the 5 nucleotide sequence of SEQ ID NO:3, etc. SEQ ID NOs:95-119 are PCR primers.

DEFINITIONS

20 For clarity, certain terms used in the specification are defined and presented as

follows: "Associated with / operatively linked" refer to two nucleic acid sequences that are related physically or functionally. For example, a promoter or regulatory DNA sequence is said to be "associated with" a DNA sequence that codes for an RNA or a protein if the 25 two sequences are operatively linked, or situated such that the regulator DNA sequence will affect the expression level of the coding or structural DNA sequence.

A "chimeric construct" is a recombinant nucleic acid sequence in which a promoter or regulatory nucleic acid sequence is operatively linked to, or associated with, a nucleic acid sequence that codes for an mRNA or which is expressed as a protein, such 30 that the regulatory nucleic acid sequence is able to regulate transcription or expression of the associated nucleic acid sequence. The regulatory nucleic acid sequence of the chimeric construct is not normally operatively linked to the associated nucleic acid sequence as found in nature.

- 6 Co-factor: natural reactant, such as an organic molecule or a metal ion, required in an enzyme-catalyzed reaction. A co-factor is e.g NAD(P), riboflavin (including FAD and FMN), folate, molybdopterin, thiamin, biotin, lipoic acid, pantothenic acid and coenzyme A, Sadenosylmethionine, pyridoxal phosphate, ubiquinone, menaquinone.

s Optionally, a co-factor can be regenerated and reused.

A "coding sequence" is a nucleic acid sequence that is transcribed into RNA such as mRNA, rRNA, tRNA, snRNA, sense RNA or antisense RNA. Preferably the RNA is then translated in an organism to produce a protein.

Complementary: "complementary" refers to two nucleotide sequences that 0 comprise antiparallel nucleotide sequences capable of pairing with one another upon formation of hydrogen bonds between the complementary base residues in the antiparallel nucleotide sequences.

Enzyme activity: means herein the ability of an enzyme to catalyze the conversion of a substrate into a product. A substrate for the enzyme comprises the 15 natural substrate of the enzyme but also comprises analogues of the natural substrate, which can also be converted, by the enzyme into a product or into an analogue of a product. The activity of the enzyme is measured for example by determining the amount of product in the reaction after a certain period of time, or by determining the amount of substrate remaining in the reaction mixture after a certain period of time. The activity of 20 the enzyme is also measured by determining the amount of an unused co-factor of the reaction remaining in the reaction mixture after a certain period of time or by determining the amount of used co-factor in the reaction mixture after a certain period of time. The activity of the enzyme is also measured by determining the amount of a donor of free energy or energy-rich molecule (e.g ATP, phosphoenolpyruvate, acetyl 2s phosphate or phosphocreatine) remaining in the reaction mixture after a certain period of time or by determining the amount of a used donor of free energy or energy-rich molecule (e.g. ADP, pyruvate, acetate or creatine) in the reaction mixture after a certain period of time.

Essential: an "essential" Arabidopsis thaliarza nucleotide sequence is a nucleotide 30 sequence encoding a protein such as e.g a biosynthetic enzyme, receptor, signal transduction protein, structural gene product, or transport protein that is essential to the growth or survival of the plant.

- 7 Expression Cassette: "Expression cassette" as used herein means a nucleic acid molecule capable of directing expression of a particular nucleotide sequence in an appropriate host cell, comprising a promoter operatively linked to the nucleotide sequence of interest which is operatively linked to temmination signals. It also typically 5 comprises sequences required for proper translation of the nucleotide sequence. The coding region usually codes for a protein of interest but may also code for a functional RNA of interest, for example antisense RNA or a nontranslated RNA, in the sense or antisense direction. The expression cassette comprising the nucleotide sequence of interest may be chimeric, meaning that at least one of its components is heterologous lo with respect to at least one of its other components. The expression cassette may also be one that is naturally occurring but has been obtained in a recombinant form useful for heterologous expression. Typically, however, the expression cassette is heterologous with respect to the host, i.e., the particular DNA sequence of the expression cassette does not occur naturally in the host cell and must have been introduced into the host cell or an 5 ancestor of the host cell by a transfommation event. The expression of the nucleotide sequence in the expression cassette may be under the control of a constitutive promoter or of an inducible promoter that initiates transcription only when the host cell is exposed to some particular external stimulus. In the case of a multicellular organism, such as a plant, the promoter can also be specific to a particular tissue or organ or stage of 20 development.

Gene: the tem' "gene" is used broadly to refer to any segment of DNA associated with a biological function. Thus, genes include coding sequences and/or the regulatory sequences required for their expression. Genes also include nonexpressed DNA segments that, for example, form recognition sequences for other proteins. Genes can be obtained 25 from a variety of sources, including cloning from a source of interest or synthesizing from known or predicted sequence information, and may include sequences designed to have desired parameters.

Heterologous/exogenous: The temms "heterologous" and "exogenous" when used herein to refer to a nucleic acid sequence (e.g a DNA sequence) or a gene, refer to a 30 sequence that originates from a source foreign to the particular host cell or, if from the same source, is modified from its original form. Thus, a heterologous gene in a host cell includes a gene that is endogenous to the particular host cell but has been modified through, for example, the use of DNA shuffling. The tempts also include non-naturally

- 8 occurring multiple copies of a naturally occurring DNA sequence. Thus, the terms refer to a DNA segment that is foreign or heterologous to the cell, or homologous to the cell but in a position within the host cell nucleic acid in which the element is not ordinarily found. Exogenous DNA segments are expressed to yield exogenous polypeptides.

s A "homologous" nucleic acid (e.g. DNA) sequence is a nucleic acid (e.g DNA) sequence naturally associated with a host cell into which it is introduced.

Hybridization: The phrase "hybridizing specifically to" refers to the binding, duplexing, or hybridizing of a molecule only to a particular nucleotide sequence under stringent conditions when that sequence is present in a complex mixture (e.g. total lo cellular) DNA or RNA. "Bind(s) substantially" refers to complementary hybridization between a probe nucleic acid and a target nucleic acid and embraces minor mismatches that can be accommodated by reducing the stringency of the hybridization media to achieve the desired detection of the target nucleic acid sequence.

Inhibitor: a chemical substance that inactivates the enzymatic activity of a protein IS such as a biosynthetic enzyme, receptor, signal transduction protein, structural gene product, or transport protein. The term "herbicide" (or "herbicidal compound") is used herein to define an inhibitor applied to a plant at any stage of development, whereby the herbicide inhibits the growth of the plant or kills the plant.

Interaction: quality or state of mutual action such that the effectiveness or toxicity 20 of one protein or compound on another protein is inhibitory (antagonists) or enhancing (agonists). A nucleic acid sequence is "isocoding with" a reference nucleic acid sequence when the nucleic acid sequence encodes a polypeptide having the same amino acid sequence as the polypeptide encoded by the reference nucleic acid sequence.

Is Isogenic: plants that are genetically identical, except that they may differ by the presence or absence of a heterologous DNA sequence.

Isolated: in the context of the present invention, an isolated DNA molecule or an isolated enzyme is a DNA molecule or enzyme that, by the hand of man, exists apart from its native environment and is therefore not a product of nature. An isolated DNA 30 molecule or enzyme may exist in a purified form or may exist in a non-native environment such as, for example, in a transgenic host cell.

Mature protein: protein from which the transit peptide, signal peptide, and/or propeptide portions have been removed.

_ Q _ Minimal Promoter: the smallest piece of a promoter, such as a TATA element, that can support any transcription. A minimal promoter typically has greatly reduced promoter activity in the absence of upstream activation. In the presence of a suitable transcription factor, the minimal promoter functions to permit transcription.

5 Modified Enzyme Activity: enzyme activity different from that which naturally occurs in a plant (i. e. enzyme activity that occurs naturally in the absence of direct or indirect manipulation of such activity by man) , which is tolerant to inhibitors that inhibit the naturally occurring enzyme activity.

Native: refers to a gene that is present in the genome of an untransformed plant 10 cell. Naturally occurring: the term "naturally occurring" is used to describe an object that can be found in nature as distinct from being artificially produced by man. For example, a protein or nucleotide sequence present in an organism (including a virus), which can be isolated from a source in nature and which has not been intentionally 15 modified by man in the laboratory, is naturally occurring.

Nucleic acid: the term "nucleic acid" refers to deoxyribonucleotides or ribonucleotides and polymers thereof in either single- or double-stranded form. Unless specifically limited, the term encompasses nucleic acids containing known analogues of natural nucleotides which have similar binding properties as the reference nucleic acid go and are metabolized in a manner similar to naturally occurring nucleotides. Unless otherwise indicated, a particular nucleic acid sequence also implicitly encompasses conservatively modified variants thereof (e.g degenerate codon substitutions) and complementary sequences and as well as the sequence explicitly indicated. Specifically, degenerate codon substitutions may be achieved by generating sequences in which the 25 third position of one or more selected (or all) codons is substituted with mixed-base and/or deoxyinosine residues (Batzer et al., Nucleic Acid Res. 19: 5081 (1991); Ohtsuka et al., J. Biol. Chem. 260: 2605-2608 (1985); Rossolini et al., Mol. Cell. Probes 8: 91-98 (1994)). The terms "nucleic acid" or "nucleic acid sequence" may also be used interchangeably with gene, cDNA, and mRNA encoded by a gene.

30 "ORF" means open reading frame.

Percent identity: the phrases "percent identical" or 'percent identical," in the context of two nucleic acid or protein sequences, refers to two or more sequences or subsequences that have for example 60%, preferably 70%, more preferably 80%, still

- 10 more preferably 90%, even more preferably 95%, and most preferably at least 99% nucleotide or amino acid residue identity, when compared and aligned for maximum correspondence, as measured using one of the following sequence comparison algorithms or by visual inspection. Preferably, the percent identity exists over a region of the 5 sequences that is at least about 50 residues in length, more preferably over a region of at least about 100 residues, and most preferably the percent identity exists over at least about 150 residues. In an especially preferred embodiment, the percent identity exists over the entire length of the coding regions.

For sequence comparison, typically one sequence acts as a reference sequence to 0 which test sequences are compared. When using a sequence comparison algorithm, test and reference sequences are input into a computer, subsequence coordinates are designated if necessary, and sequence algorithm program parameters are designated. The sequence comparison algorithm then calculates the percent sequence identity for the test sequence(s) relative to the reference sequence, based on the designated program 5 parameters. Optimal alignment of sequences for comparison can be conducted, e.g. by the local homology algorithm of Smith & Waterman, Adv. Appl. Math. 2: 482 (1981), by the homology alignment algorithm of Needleman & Wunsch, J. Mol. Biol. 48: 443 (1970), by the search for similarity method of Pearson & Lipman, Proc. Nat 'l. Acad. Sci. USA 20 85: 2444 (1988), by computerized implementations of these algorithms (GAP, BESTFIT, FASTA, and TFASTA in the Wisconsin Genetics Software Package, Genetics Computer Group, 575 Science Dr., Madison, WI), or by visual inspection (see generally, Ausubel et al., irfra).

One example of an algorithm that is suitable for determining percent sequence 25 identity and sequence similarity is the BLAST algorithm, which is described in Altschul et al., J. Mol. Biol. 215: 403-410 (1990). Software for performing BLAST analyses is publicly available through the National Center for Biotechnology Information (http://www.ncbi.nlm.nih. gov/). This algorithm involves first identifying high scoring sequence pairs (HSPs) by identifying short words of length W in the query sequence, 30 which either match or satisfy some positive-valued threshold score T when aligned with a word of the same length in a database sequence. T is referred to as the neighborhood word score threshold (Altschul et al., 1990). These initial neighborhood word hits act as seeds for initiating searches to find longer HSPs containing them. The word hits are then

- 11 extended in both directions along each sequence for as far as the cumulative alignment score can be increased. Cumulative scores are calculated using, for nucleotide sequences, the parameters M (reward score for a pair of matching residues; always > 0) and N (penalty score for mismatching residues; always < 0). For amino acid sequences, s a scoring matrix is used to calculate the cumulative score. Extension of the word hits in each direction are halted when the cumulative alignment score falls off by the quantity X from its maximum achieved value, the cumulative score goes to zero or below due to the accumulation of one or more negative-scoring residue alignments, or the end of either sequence is reached. The BLAST algorithm parameters W. T. and X determine the 10 sensitivity and speed of the alignment. The BLASTN program (for nucleotide sequences) uses as defaults a wordlength (W) of 11, an expectation (E) of 10, a cutoff of 100, M=5, N=-4, and a comparison of both strands. For amino acid sequences, the BLASTP program uses as defaults a wordlength (W) of 3, an expectation (E) of 10, and the BLOSUM62 scoring matrix (see Henikoff & Henikoff, Proc. Natl. Acad. Sci. USA 89: 5 10915 (1989)).

In addition to calculating percent sequence identity, the BLAST algorithm also performs a statistical analysis of the similarity between two sequences (see, e.g. Karlin & Altschul, Proc. Nat 'l. Acad. Sci. USA 90: 5873-5787 (1993)). One measure of similarity provided by the BLAST algorithm is the smallest sum probability (P(N)), 20 which provides an indication of the probability by which a match between two nucleotide or amino acid sequences would occur by chance. For example, a test nucleic acid sequence is considered similar to a reference sequence if the smallest sum probability in a comparison of the test nucleic acid sequence to the reference nucleic acid sequence is less than about 0.1, more preferably less than about 0.01, and most preferably less than 25 about 0.001.

Pre-protein: protein that is normally targeted to a cellular organelle, such as a chloroplast, and still comprises its native transit peptide.

Purified: the term "purified," when applied to a nucleic acid or protein, denotes that the nucleic acid or protein is essentially free of other cellular components with which 30 it is associated in the natural state. It is preferably in a homogeneous state although it can be in either a dry or aqueous solution. Purity and homogeneity are typically determined using analytical chemistry techniques such as polyacrylamide gel electrophoresis or high performance liquid chromatography. A protein that is the predominant species present in

- 12 a preparation is substantially purified. The term "purified" denotes that a nucleic acid or protein gives rise to essentially one band in an electrophoretic gel. Particularly, it means that the nucleic acid or protein is at least about 50% pure, more preferably at least about 85% pure, and most preferably at least about 99% pure.

5 Two nucleic acids are "recombined" when sequences from each of the twonucleic acids are combined in a progeny nucleic acid. Two sequences are "directly" recombined when both of the nucleic acids are substrates for recombination. Two sequences are "indirectly recombined" when the sequences are recombined using an intermediate such as a cross-over oligonucleotide. For indirect recombination, no more lo than one ofthe sequences is an actual substrate for recombination, and in some cases, neither sequence is a substrate for recombination.

"Regulatory elements" refer to sequences involved in controlling the expression of a nucleotide sequence. Regulatory elements comprise a promoter operatively linked to the nucleotide sequence of interest and termination signals. They also typically 5 encompass sequences required for proper translation of the nucleotide sequence.

Significant Increase: an increase in enzymatic activity that is larger than the margin of error inherent in the measurement technique, preferably an increase by about 2-fold or greater of the activity of the wild-type enzyme in the presence of the inhibitor, more preferably an increase by about 5-fold or greater, and most preferably an increase 20 by about 1 O-fold or greater.

Significantly less: means that the amount of a product of an enzymatic reaction is reduced by more than the margin of error inherent in the measurement technique, preferably a decrease by about 2-fold or greater of the activity of the wild-type enzyme in the absence of the inhibitor, more preferably an decrease by about 5-fold or greater, and 25 most preferably an decrease by about 1 O-fold or greater.

Specific Binding/Immunological Cross-Reactivity: An indication that two nucleic acid sequences or proteins are substantially identical is that the protein encoded by the first nucleic acid is immunologically cross reactive with, or specifically binds to, the protein encoded by the second nucleic acid. Thus, a protein is typically substantially so identical to a second protein, for example, where the two proteins differ only by conservative substitutions. The phrase "specifically (or selectively) binds to an antibody," or "specifically (or selectively) immunoreactive with," when referring to a protein or peptide, refers to a binding reaction which is determinative of the presence of

- 13 the protein in the presence of a heterogeneous population of proteins and other biologics.

Thus, under designated immunoassay conditions, the specified antibodies bind to a particular protein and do not bind in a significant amount to other proteins present in the sample. Specific binding to an antibody under such conditions may require an antibody s that is selected for its specificity for a particular protein. For example, antibodies raised to the protein with the amino acid sequence encoded by any of the nucleic acid sequences of the invention can be selected to obtain antibodies specifically immunoreactive with that protein and not with other proteins except for polymorphic variants. A variety of immunoassay formats may be used to select antibodies specifically imrnunoreactive with lo a particular protein. For example, solid-phase ELISA immunoassays, Western blots, or immunohistochemistry are routinely used to select monoclonal antibodies specifically irnmunoreactive with a protein. See Harlow and Lane (1988) Antibodies, A Laboratory Manual, Cold Spring Harbor Publications, New York "Harrow and Lane"), for a description of immunoassay formats and conditions that can be used to determine

15 specific immunoreactivity. Typically a specific or selective reaction will be at least twice background signal or noise and more typically more than 10 to 100 times background.

"Stringent hybridization conditions" and "stringent hybridization wash conditions" in the context of nucleic acid hybridization experiments such as Southern and Northern hybridizations are sequence dependent, and are different under different 20 environmental parameters. Longer sequences hybridize specifically at higher temperatures. An extensive guide to the hybridization of nucleic acids is found in Tijssen (1993) Laboratory Techniques in Biochemistry and Molecular Biology-Hybridization with Nucleic Acid Probes part I chapter 2 "Overview of principles of hybridization and the strategy of nucleic acid probe assays" Elsevier, New York. Generally, highly 2s stringent hybridization and wash conditions are selected to be about 5 C lower than the thermal melting point (Tm) for the specific sequence at a defined ionic strength and pH.

Typically, under "stringent conditions" a probe will hybridize to its target subsequence, but to no other sequences.

The Tm is the temperature (under defined ionic strength and pH) at which 50% of 30 the target sequence hybridizes to a perfectly matched probe. Very stringent conditions are selected to be equal to the Tm for a particular probe. An example of stringent hybridization conditions for hybridization of complementary nucleic acids which have more than 100 complementary residues on a filter in a Southern or northern blot is 50%

- 14 formamide with I mg of heparin at 42 C, with the hybridization being carried out overnight. An example of highly stringent wash conditions is 0.1 5M NaCI at 72 C for about 15 minutes. An example of stringent wash conditions is a 0.2x SSC wash at 65 C for 15 minutes (see, Sambrook, Indira, for a description of SSC buffer). Often, a high

5 stringency wash is preceded by a low stringency wash to remove background probe

signal. An example medium stringency wash for a duplex of, e.g. more than 100 nucleotides, is lx SSC at 45 C for 15 minutes. An example low stringency wash for a duplex of, e.g. more than 100 nucleotides, is 4-6x SSC at 40 C for 15 minutes. For short probes (e.g. about 10 to 50 nucleotides), stringent conditions typically involve salt 10 concentrations of less than about 1.0 M Na ion, typically about 0.01 to 1.0 M Na ion concentration (or other salts) at pH 7.0 to 8.3, and the temperature is typically at least about 30 C. Stringent conditions can also be achieved with the addition of destabilizing agents such as formamide. In general, a signal to noise ratio of 2x (or higher) than that observed for an unrelated probe in the particular hybridization assay indicates detection 5 of a specific hybridization. Nucleic acids that do not hybridize to each other under stringent conditions are still substantially identical if the proteins that they encode are substantially identical. This occurs, e.g. when a copy of a nucleic acid is created using the maximum codon degeneracy permitted by the genetic code.

The following are examples of sets of hybridization/wash conditions that may be 20 used to clone nucleotide sequences that are homologues of reference nucleotide sequences of the present invention: a reference nucleotide sequence preferably hybridizes to the reference nucleotide sequence in 7% sodium dodecyl sulfate (SDS), 0.5 M NaPO., 1 mM EDTA at 50 C with washing in 2X SSC, 0.1% SDS at 50 C, more desirably in 7% sodium dodecyl sulfate (SDS), 0.5 M NaPO4, 1 mM EDTA at 50 C with washing in 1X 25 SSC, 0.1% SDS at 50 C, more desirably still in 7% sodium dodecyl sulfate (SDS), 0.5 M NaPO4, 1 mM EDTA at 50 C with washing in 0.5X SSC, 0. 1% SDS at 50 C, preferably in 7% sodium dodecyl sulfate (SDS), 0.5 M NaPO4, 1 mM EDTA at 50 C with washing in 0.1X SSC, 0.1% SDS at 50 C, more preferably in 7% sodium dodecyl sulfate (SDS), 0.5 M NaPO4, 1 mM EDTA at 50 C with washing in 0.1X SSC, 0.1% SDS at 65 C.

30 A "subsequence" refers to a sequence of nucleic acids or amino acids that comprise a part of a longer sequence of nucleic acids or amino acids (e.g., protein) respectively.

- 15 Substrate: a substrate is the molecule that an enzyme naturally recognizes and converts to a product in the biochemical pathway in which the enzyme naturally carries out its function, or is a modified version of the molecule, which is also recognized by the enzyme and is converted by the enzyme to a product in an enzymatic reaction similar to s the naturally-occurring reaction.

Transformation: a process for introducing heterologous DNA into a plant cell, plant tissue, or plant. Transformed plant cells, plant tissue, or plants are understood to encompass not only the end product of a transformation process, but also transgenic progeny thereof.

10 "Transformed," "transgenic," and "recombinant" refer to a host organism such as a bacterium or a plant into which a heterologous nucleic acid molecule has been introduced. The nucleic acid molecule can be stably integrated into the genome of the host or the nucleic acid molecule can also be present as an extrachromosomal molecule.

Such an extrachromosomal molecule can be auto-replicating. Transformed cells, tissues, Is or plants are understood to encompass not only the end product of a transformation process, but also transgenic progeny thereof. A "non-transformed," "non-transgenic," or "non-recombinant" host refers to a wild-type organism, e.g., a bacterium or plant, which does not contain the heterologous nucleic acid molecule.

Viability: 'viability" as used herein refers to a fitness parameter of a plant.

20 Plants are assayed for their homozygous performance of plant development, indicating which proteins are essential for plant growth.

DETAILED DESCRIPTION OF THE INVENTION

as I. Identification of Essential Arabidopsis thaliana Nucleotide Sequences and Encoded Proteins Using AclDs Transposon or T-DNA-Mediated Mutagenesis As shown in the examples below, the essentiality of the nucleotide sequences described herein for normal plant growth and development, have been demonstrated for the first time in Arabidopsis using AclDs transposon or T-DNA-mediated mutagenesis.

30 Having established the essentiality of the function of the encoded proteins in Arabidopsis thaliana and having identified the nucleotide sequences encoding these essential proteins, the inventors thereby provide an important and sought after tool for new herbicide development.

- 16 Arabidopsis insertional mutant lines segregating for seedling lethal mutations are identified as a first step in the identification of essential proteins. Starting with T2 seeds collected from single T1 plants containing T-DNA insertions in their genomes, those lines segregating homozygous seedling lethal seedlings are identified. Ds transposon s insertion lines are produced as described in Sundaresan et al. (1995) (Genes and Dev., 9:1797-1810), incorporated herein by reference. Starting with F3 or F4 seeds collected from single F2 or F3 kanamycin-resistant plants containing Ds insertions in their genomes (see Figure 3 of Sundaresan et al. (1995) (Genes and Dev., 9: 1797-1810), those lines segregating homozygous seedling lethal seedlings are identified. These lines are lo found by placing seeds onto minimal plant growth media, which contains the fungicides benomyl and maxim, and screening for inviable seedlings after 7 and 14 days in the light at room temperature. Inviable phenotypes include altered pigmentation or altered morphology. These phenotypes are observed either on plates directly or in soil following transplantation of seedlings.

15 Essential genes are also identified through the isolation of lethal mutants blocked in early development. Examples of lethal mutants include those blocked in the formation of the male or female gametes or embryo. Gametophytic mutants are found by examining T1 insertion lines for the presence of 50% aborted pollen grains or ovules.

Embryo defective mutants produce 25% defective seeds following selfpollination of T1 20 plants (see Errampalli et al. 1991, Plant Cell 3:149157; Castle et al. 1993, Mol Gen Genet 241:504-514).

When a line is identified as segregating a seedling lethal or an embryo defective phenotype, it is determined if the resistance marker in the Ds transposon or T-DNA insertion co-segregates with the lethality (Errampalli et al. (1991) The Plant Cell, 3:149 25 157). Cosegregation analysis is done by placing the seeds on media containing the selective agent and scoring the seedlings for resistance or sensitivity to the agent.

Examples of selective agents used are kanamycin, hygromycin, or phosphinothricin.

About 35 resistant seedlings are transplanted to soil and their progeny are examined for the segregation of the seedling lethal. In the case in which the Ds transposon or T-DNA 30 insertion disrupts an essential gene, there is co-segregation of the resistance phenotype and the seedling lethal or embryo defective phenotype in every plant. Therefore, in such a case, all resistant plants segregate a seedling lethal or embryo defective phenotype in

- 17 the next generation; this result indicates that each of the resistant plants is heterozygous for the mutation and hemizygous for the T-DNA insert causing the mutation.

For the Arabidopsis lines showing co-segregation of the transposonencoded or T-DNA-encoded resistance marker and the lethal phenotype, PCRbased molecular 5 approaches such as, TAIL-PCR (Liu et al. (1995) Plant J. , 8:457-463; Liu and Whittier (1995), Genomics, 25:674-681), TAIL2k, vectorette PCR (Riley et al. (1990) Nucleic Acids Research, 18: 2887-2890) ), or the GenomeWalker_ kit (CLONTECH Laboratories, Inc., Palo Alto, CA), may be used to directly amplify the plant DNA fragments flanking the transposon or T-DNA. Each of these techniques utilizes the lo known sequence of the transposon or T-DNA, and can be used to recover small (less than 5 kb) fragments directly adjacent to the insertion. PCR products are isolated and their DNA sequence is determined.

Alternatively, plasmid rescue may be used to isolate the plant DNA/T-DNA border fragments. Southern blot analysis may be performed as an initial step in the 5 characterization of the molecular nature of each insertion. Southern blots are done with genomic DNA isolated from heterozygotes and using probes capable of hybridizing with the T-DNA vector DNA. Using the results of the Southern analysis, appropriate restriction enzymes are chosen to perform plasmid rescue in order to molecularly clone Arabidopsis thaliana genomic DNA flanking one or both sides of the T-DNA insertion.

20 Plasmids obtained in this manner are analyzed by restriction enzyme digestion to sort the plasmids into classes based on their digestion pattern. For each class of plasmid clone, the DNA sequence is determined.

The resulting sequences, obtained by any of the above outlined approaches, are analyzed for the presence of non-De transposon and non-T-DNA vector sequences, as 25 appropriate. When such sequences are found, they are used to search DNA and protein databases using the BLAST and BLAST2 programs (Altschul et al. (1990) J Mol. Biol.

215: 403-410; Altschul et al. (1997) Nucleic Acid Res. 25:3389-3402, both incorporated herein by reference). Additional genomic and cDNA sequences for each gene are identified by standard molecular biology procedures.

II. Recombinant Production Of Essential Proteins And Uses Thereof For recombinant production of a protein of the invention in a host organism, a nucleotide sequence encoding the protein is inserted into an expression cassette designed

- 18 for the chosen host and introduced into the host where it is recombinantly produced. The choice of the specific regulatory sequences such as promoter, signal sequence, 5' and 3' untranslated sequence, and enhancer appropriate for the chosen host is within the level of the skill of the routineer in the art. The resultant molecule, containing the individual s elements linking in the proper reading frame, is inserted into a vector capable of being transformed into the host cell. Suitable expression vectors and methods for recombinant production of proteins are well known for host organisms such as E. colt, yeast, and insect cells (see, e.g. Lucknow and Summers, Bio/Technol. 6:47 (1988)). Additional suitable expression vectors are baculovirus expression vectors, e.g. those derived from lo the genome of Autographica californica nuclear polyhedrosis virus (AcMNPV). A preferred baculovirus/insect system is PVL1392(3) used to transfect Spodoptera frugiperda SF9 cells (ATCC) in the presence of linear Autographica californica baculovirus DNA (Phramingen, San Diego, CA). The resulting virus is used to infect HighFive Tricoplusia ni cells (Invitrogen, La Jolla, CA).

5 Recombinantly produced proteins are isolated and purified using a variety of standard techniques. The actual techniques used vary depending upon the host organism used, whether the protein is designed for secretion, and other such factors. Such techniques are well known to the skilled artisan (see, e.g chapter 16 of Ausubel, F. et al., "Current Protocols in Molecular Biology", pub. by John Wiley & Sons, Inc. (1994).

III. Assays For Characterizing The Essential Proteins The recombinantly produced proteins described herein are useful for a variety of purposes. For example, they can be used in in vitro assays to screen known herbicidal chemicals whose target has not been identified to determine if they inhibit protein 25 activity. Such in vitro assays may also be used as more general screens to identify chemicals that inhibit such protein activity and that are therefore novel herbicide candidates. Recombinantly produced proteins may also be used to elucidate the complex structure of these molecules and to further characterize their association with known inhibitors in order to rationally design new inhibitory herbicides. Alternatively, the 30 recombinant protein can be used to isolate antibodies or peptides that modulate the activity and are useful in transgenic solutions.

- 19 IV. In vitro Inhibitor Assay: Discovery of Small Molecule Ligands That Interact with Essential Proteins Of Unknown Biochemical Function Once a protein has been identified as a potential herbicide target based on its essentiality for normal plant growth and viability, a next step is to develop an assay that 5 allows screening large number of chemicals to determine which ones interact with the protein. Although it is straightforward to develop assays for proteins of known function, developing assays with proteins of unknown functions can be more difficult.

To address this issue, novel technologies are used that can detect interactions between a protein and a compound without knowing the biological function of the 0 protein. A short description of three methods is presented, including fluorescence

correlation spectroscopy, surface-enhanced laser desorption/ionization, and biacore technologies. Fluorescence Correlation Spectroscopy (FCS) theory was developed in 1972 but it is only in recent years that the technology to perform FCS became available (Madge et 5 al. (1972) Phys. Rev. Lett., 29: 705-708; Maiti et al. (1997) Proc. Natl. Acad. Sci. USA, 94: 11753-11757). FCS measures the average diffusion rate of a fluorescent molecule within a small sample volume. The sample size can be as low as 103 fluorescent molecules and the sample volume as low as the cytoplasm of a single bacterium. The diffusion rate is a function of the mass of the molecule and decreases as the mass 20 increases. FCS can therefore be applied to protein-ligand interaction analysis by measuring the change in mass and therefore in diffusion rate of a molecule upon binding.

In a typical experiment, the target to be analyzed is expressed as a recombinant protein with a sequence tag, such as a poly-histidine sequence, inserted at the N or C-terminus.

The expression takes place in E. colt, yeast or insect cells. The protein is purified by 25 chromatography. For example, the poly-histidine tag can be used to bind the expressed protein to a metal chelate column such as Ni2+ chelated on iminodiacetic acid agarose.

The protein is then labeled with a fluorescent tag such as carboxytetramethylrhodamine or BODIPY() (Molecular Probes, Eugene, OR). The protein is then exposed in solution to the potential ligand, and its diffusion rate is determined by FCS using instrumentation 30 available from Carl Zeiss, Inc. (Thornwood, NY). Ligand binding is determined by changes in the diffusion rate of the protein.

Surface-Enhanced Laser Desorption/Ionization (SELDI) was invented by Hutchens and Yip during the late 1980's (Hutchens and Yip (1993) Rapid Commun.

- 20 Mass Spectrom. 7: 576-580). When coupled to a time-of-flight mass spectrometer (TOP), SELDI provides a mean to rapidly analyze molecules retained on a chip. It can be applied to ligand-protein interaction analysis by covalently binding the target protein on the chip and analyze by MS the small molecules that bind to this protein (Worrall et 5 al. (1998) Anal. Biochem. 70: 750-756). In a typical experiment, the target to be analyzed is expressed as described for FCS. The purified protein is then used in the assay without further preparation. It is bound to the SELDI chip either by utilizing the poly-histidine tag or by other interaction such as ion exchange or hydrophobic interaction. The chip thus prepared is then exposed to the potential ligand via, for 0 example, a delivery system capable to pipette the ligands in a sequential manner (autosampler). The chip is then submitted to washes of increasing stringency, for example a series of washes with buffer solutions containing an increasing ionic strength.

After each wash, the bound material is analyzed by submitting the chip to SELDI-TOF.

Ligands that specifically bind the target will be identified by the stringency of the wash 5 needed to elate them.

Biacore relies on changes in the refractive index at the surface layer upon binding of a ligand to a protein immobilized on the layer. In this system, a collection of small ligands is injected sequentially in a 2-5 microlitre cell with the immobilized protein.

Binding is detected by surface plasmon resonance (SPR) by recording laser light 20 refracting from the surface. In general, the refractive index change for a given change of mass concentration at the surface layer, is practically the same for all proteins and peptides, allowing a single method to be applicable for any protein (Liedberg et al. (1983) Sensors Actuators 4: 299-304; Malmquist (1993) Nature, 361: 186-187). In a typical experiment, the target to be analyzed is expressed as described for FCS. The 25 purified protein is then used in the assay without further preparation. It is bound to the Biacore chip either by utilizing the poly-histidine tag or by other interaction such as ion exchange or hydrophobic interaction. The chip thus prepared is then exposed to the potential ligand via the delivery system incorporated in the instruments sold by Biacore (Uppsala, Sweden) to pipette the ligands in a sequential manner (autosampler). The SPR 30 signal on the chip is recorded and changes in the refractive index indicate an interaction between the immobilized target and the ligand. Analysis of the signal kinetics on rate and off rate allows the discrimination between non-specific and specific interaction.

- 21 Another assay for small molecule ligands that interact with a polypeptide is an inhibitor assay. For example, such an inhibitor assay useful for identifying inhibitors of the products of essential plant nucleic acid sequences, such as the essential Arabidopsis proteins described herein, comprises the steps of: 5 a) reacting an essential Arabidopsis protein described herein and a substrate thereof in the presence of a suspected inhibitor of the protein's function; b) comparing the rate of enzymatic activity of the protein in the presence of the suspected inhibitor to the rate of enzymatic activity under the same conditions in the absence of the suspected inhibitor; and lo c) determining whether the suspected inhibitor inhibits the essential Arabidopsis protein. For example, the inhibitory effect on the activity of a hereindescribed essential Arabidopsis protein, may be determined by a reduction or complete inhibition of protein activity in the assay. Such a determination may be made by comparing, in the presence 5 and absence of the candidate inhibitor, the amount of substrate used or intermediate or product made during the reaction.

V. Production of peptides Phage particles displaying diverse peptide libraries permits rapid library 20 construction, affinity selection, amplification and selection of ligands directed against an essential protein (H.B. Lowman, Annul Rev. Biophys. Biomol. Struct. 26, 401-424 (1997)). Structural analysis of these selectants can provide new information about ligand-target molecule interactions and then in the process also provide a novel molecule that can enable the development of new herbicides based upon these peptides as leads.

Vl. In Vivo Inhibitor Assay In one embodiment, a suspected herbicide, for example identified by in vitro screening, is applied to plants at various concentrations. The suspected herbicide is preferably sprayed on the plants. After application of the suspected herbicide, its effect 30 on the plants, for example death or suppression of growth is recorded.

In another embodiment, an in viva screening assay for inhibitors of the activity of a hereindescribed essential protein uses transgenic plants, plant tissue, plant seeds or plant cells capable of overexpressing a nucleotide sequence disclosed herein that encodes

- 22 an essential protein, wherein the essential protein is enzymatically active in the transgenic plants, plant tissue, plant seeds or plant cells. A chemical is then applied to the transgenic plants, plant tissue, plant seeds or plant cells and to the isogenic non-

transgenic plants, plant tissue, plant seeds or plant cells, and the growth or viability of the s transgenic and non-transformed plants, plant tissue, plant seeds or plant cells are determined after application of the chemical and compared. Compounds capable of inhibiting the growth of the non-transgenic plants, but not affecting the growth of the transgenic plants are selected as specific inhibitors of the essential protein's activity.

The invention will be further described by reference to the following detailed lo examples. These examples are provided for purposes of illustration only, and are not intended to be limiting unless otherwise specified.

EXAMPLES

5 Standard recombinant DNA and molecular cloning techniques used here are well known in the art and are described by J. Sambrook, et al., Molecular Cloning: A Laboratory Manual, 3d Ed., Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press (2001); by T.J. Silhavy, M.L. Berman, and L.W. Enquist, Experiments with Gene Fusions, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (1984) and by 20 Ausubel, F.M. et al., Current Protocols in Molecular Biology, New York, John Wiley and Sons Inc., (1988) , Reiter, et al., Methods in Arabidopsis Research, World Scientific Press (1992), and Schultz et al., Plant Molecular Biology Manual, Klawer Academic Publishers (1998). These references describe the standard techniques used for all steps in tagging and cloning genes from AclDs transposon or T-DNA mutagenized populations of 25 Arabidopsis: plant infection and transformation; screening for the identification of seedling mutants; and cosegregation analysis. Ds transposon insertion lines produced as described in Sundaresan et al. (1995) Genes and Dev., 9:1797-1810) are used in these experiments. T-DNA lines are generated using vacuum infiltration or floral dip methods (Bechtold et al. (1993) C. R. Acad. Sci. Paris, 316:1194-1199; Clough and Bent (1998) 30 Plant J., 16:735-743; Desfeux et al. (2000) Plant Physiol., 123:895-904).

- 23 Example 1: Identification of Arabidopsis Mutants with Lethal Phenotypes Essential genes are identified through the isolation of lethal mutants blocked in early development. Examples of lethal mutants include those blocked in the formation of 5 the male or female gametes, embryo, or resulting seedling. Gametophytic mutants are found by examining insertion lines for the presence of 50% aborted pollen grains or ovules. Embryo defective lethal mutants usually produce 25% defective seeds following self-pollination of plants heterozygous for an insertion (see Errampalliet al. 1991, Plant Cell 3:149-157; Castle et al. 1993, Mol Gen Genet 241:504-514). Seedling lethal lo mutants usually segregate 25% seedlings that exhibit a lethal phenotype.

Example 2: Cosegregation Analysis for Lines with Lethal Phenotypes The linkage of the mutation to the Ds or T-DNA insertion is established after Is identifying a transformed line segregating for a lethal phenotype of interest. A line segregating with a single functional insert will segregate for resistance in the ratio of about 2:1 (resistant: sensitive) to the selectable marker. In the case of an embryo defective mutant, onequarter of the progeny of a plant heterozygous for an insertion will fail to germinate due to embryo lethality, resulting in a reduction of the normal 3:1 ratio 20 to 2:1. In the case of a seedling lethal mutant, the seedlings with a mutant phenotype are excluded in the calculation of this ratio. Each of the resistant progeny is therefore heterozygous for the mutation if the Ds or T-DNA insertion is causing the mutant phenotype. To establish cosegregation of the insertion and the mutant phenotype, about 30 resistant progeny are transplanted to soil and each plant is shown to segregate the 25% 25 progeny with a lethal phenotype by the appropriate screening of embryo or seedlings.

When all resistant plants segregate the lethal phenotype, there is cosegregation of the insertion and the lethal mutation and the line is designated as "tagged."

Example 3: T-DNA Border Isolation by Plasmid Rescue The plasmid rescue technique is used to molecularly clone Arabidopsis flanking DNA from one or both sides of the T-DNA insertion(s). Arabidopsis genomic DNA is isolated as described by Reiter et al. in Methods in Arabidopsis Research, World

- 24 Scientific Press (1992). Genomic DNA is digested with a restriction endonuclease and ligated overnight. After ligation, the DNA is transformed into competent E. cold strain XL-1 Blue, DH1OB, DH5 alpha, or the like, and colonies are selected on semi-solid medium containing ampicillin. Resistant colonies are picked into liquid medium with 5 ampicillin and grown overnight. Plasmid DNA is isolated and digested with the rescue enzyme and analyzed on agarose gels containing ethidium bromide for visualization.

Plasmids that represent different size classes are sequenced using primers that flank the plant DNA portion of the rescue element and the sequence is analyzed to determine what portion is plant DNA and what gene has been disrupted. The plasmid rescue is validated 10 via PCR of template genomic DNA from a heterozygote for the insertion mutation. The experiment uses a primer anchored in the predicted flanking sequence and a primer in the T-DNA insertion. Finding a PCR product of the appropriate size, based on the sequence of the plasmid rescue clone confirms a valid rescue. Alternatively, Southern blot analysis with a probe that detects the relevant region of Arabidopsis DNA in genomic DNA from 15 a heterozygote for the insertion mutation can be used to confirm the plasmid rescue results. Example 4: Transposon or T-DNA Border Isolation by TAIL-PCR 20 Arabidopsis genomic DNA is isolated according to Reiter et al. in Methods in Arabidopsis Research, World Scientific Press (1992) or using the Nucleon PhytoPure_ Plant DNA isolation kit (Amersham International plc, Buckinghamshire, England) or the Puregene DNA isolation kit (Gentra Systems, Minneapolis, MN). Fragments of genomic DNA flanking the borders of the transposon or T-DNA are isolated using the TAIL-PCR 2s technique (Liu et al. (1995) Plant J., 8:457-463; Liu and Whittier (1995), Genomics, 25:674-681). Three sets of 12 TAIL-PCR reactions, referred to as the primary, secondary and tertiary reactions, are performed. In each reaction, one arbitrary degenerate primer and one transposon-specific or T-DNA-specific primer are used. The arbitrary degenerate primer is chosen from among seven primers, LWAD1, CA50, CA51, 30 CA52, CA53, CA54, and CA55 (Table 1), which are used to prime the genomic DNA flanking the insertion. Alternatively, less than 12 TAIL-PCR reactions are done using fewer arbitrary degenerate primers. These degenerate primers are used in combination with two sets of three, nested, transposon-specific primers (Table 2) or T-DNA-specific

- 25 primers (Table 3). The transposon-specific primers are homologous to regions of the Ds elements that lie at the outermost ends of the transposons, DS5 at the 5' end (primers 5A, 5B, and 5C) and DS3 at the 3' end (primers 3A, 3B, and 3C). The T-DNA-specific primers are homologous to regions of the T-DNA that lie in the borders of the T-DNAs.

5 For the pCSA104 and pDAP101 T-DNAs, right borders are recovered with CA66 (primary primer), CA67 (secondary primer), and CA68 (tertiary primer) and left borders are recovered with JM33 (tertiary primer); JM34 (secondary primer); and JM35 (primary primer). For the pCSAl to T-DNA, right borders are recovered with QRB1 (primary primer), QRB2 (secondary primer), and QRB3 (tertiary primer) and left borders are lo recovered with JM33 (tertiary primer); JM34 (secondary primer); and JM35 (primary primer). For the pPCVICEn4HPT (Hayashi et al. (1992), Science, 258:13501353) and pSKI015 (Weigel et al. (2000) Plant Physiol. 122:1003-1014) TDNAs, left borders are recovered with SKIT (primary primer), SKI2 (secondary primer), and SKI3 (tertiary primer). When the degenerate and nested primer pairs are used in a series of low and 5 high-stringency PCR amplifications, as described in the TAIL-PCR protocol (Liu and Whittier (1995), Genomics, 25:674-681), DNA fragments are produced that correspond to the genomic DNA that is directly adjacent to the transposon or T-DNA insertion. The nucleic acid sequences of the PCR products from the tertiary TAIL-PCR reactions are then determined by standard molecular biology techniques. The resulting sequences are 20 analyzed for the presence of non-De transposon or non-T-DNA vector sequence.

To confirm the integrity of the resultant products, PCR primers specific to the flanking genomic region are designed and used in conjunction with the tertiary nested primer in a PCR reaction, to confirm the transposon or T-DNA insertion point within the genomic DNA. Finding a PCR product of the appropriate size, based on the sequence of 2s the TAIL-PCR clone confirms a valid rescue.

Table 1: Arbitrary Degenerate Primers SEQ ID NO: Primer Degen. Primer Sequence 95 LWAD1 1026 ngt tgw gna twt saw ant 30 96 CA50 128 ngt cga swg ana wga a 97 CA51 128 tgw gna gsa nca sag a 98 CA52 128 agw gna gwa nca wag g 99 CA53 256 stt ant ast nct ntg c

- 26 100 CA54 64 ntc gas twt saw gtt 101 CA55 256 wgt gna gwa nca nag a Table 2: Nested Primers For Ds Lines 5 SEO ID NO: Primer Primer Sequence 102 5A actagctctaccgtttccgtttccgmac 103 5B ttacctcgggttcgaaatcgatcgggataa 104 5C aaaatcggttatacgataacggtcggtacggga 105 3A gggtcttgcggatctgaetatatgttttcatgtgtg o 106 3B taccgaagaaaaataccggttcccgtccgatttcgac 107 3C ggatcgtatcggttttcgattaccgtamatcc Table 3: Nested Primers For T-DNA Lines SEQ ID NO: Primer Primer Sequence 5 108 CA66 att egg cac ccc egg ctt tac act tta tg 109 CA67 gta tat tat gtg gaa ttg tga gcg get aac 110 CA68 tea caa ttt cac ace gga aac agc tat gac 111 JM33 tag cat ctg eat ttc ata acc eat ctc get ace c 112 JM34 act tcc tat tat ale ttc cca eat tac caa tac a 20 113 JM35 gcc ttt lea gaa atg get aaa tag cct tgc ttc c 114 QRB1 caa act egg ata eat tat cgc gcg cgg tat ca 115 QRB2 ggt gtc ale tat gtt act age leg gga att ga 116 QRB3 cgc cat ggc ata tgc tag cat gca tea ttc 117 SKIT eat tag tea tta ctc m ctt ttc ctc cat att ga 25 118 SKI2 ata ttg acc ale ata ctc att act get cca t 119 SKI3 tga tcc atg tag att tcc cgg ace tga a Example 5: Transposon or T-DNA Border Isolation by TAIL2k PCR 30 Arabidopsis genomic DNA is isolated according to Reiter et al. in Methods in Arabidopsis Research, World Scientific Press (1992) or using the Nucleon PhytoPure_ Plant DNA isolation kit (Amersham International plc, Buckinghamshire, England) or the Puregene DNA isolation kit (Gentra Systems, Minneapolis, MN). Fragments of genomic

- 27 DNA flanking the borders of the transposon or T-DNA are isolated using the TAIL2k PCR technique. Two sets of 12 TAIL-PCR reactions, referred to as the primary and secondary reactions, are performed. In each reaction, one arbitrary degenerate primer and one transposon- specific or T-DNA-specific primer are used. The arbitrary s degenerate primer is selected from among six primers; CA50, CA51, CA52, CA53, CA54, and CA55 (Table 1), which are used to prime the genomic DNA flanking the insertion. Alternatively, less than 12 TAIL-PCR reactions are done using fewer arbitrary degenerate primers. These degenerate primers are used in combination with two sets of two, nested, transposon-specific primers (Table 2) or T-DNA-specific primers (Table 3).

lo The transposon-specific primers are homologous to regions of the Ds elements that lie at the outermost ends of the transposons, DS5 at the 5' end (primers SA, 5B, and 5C) and DS3 at the 3' end (primers 3A, 3B, and 3C). The T-DNA-specific primers are homologous to regions of the T-DNA that lie in the borders of the T-DNAs. For the pCSA104 and pDAP101 T-DNAs, right borders are recovered with CA66 (primary 5 primer), CA67 (secondary primer), and CA68 (sequencing primer) and left borders are recovered with JM33 (sequencing primer), JM34 (secondary primer), and JM35 (primary primer). Primers CA66, CA67, and CA68 are also known as RB1, RB2, and RB3, respectively. Primers JM35, JM34, and JM33 are also known as LB1, LB2, and LB3, respectively. For the pCSA110 T-DNA, right borders are recovered with QRB1 (primary 20 primer), QRB2 (secondary primer), and QRB3 (sequencing primer) and left borders are recovered with JM33 (sequencing primer); JM34 (secondary primer); and JM35 (primary primer). For the pPCVICEn4HPT (Hayashi et al. (1992), Science, 258:1350-1353) and pSKI015 (Weigel et al. (2000) Plant Physiol. 122:1003-1014) T-DNAs, left borders are recovered with SKIT (primary primer), SKI2 (secondary primer), and SKI3 (sequencing s primer). When the degenerate and nested primer pairs are used in a series of low and high-stringency PCR amplifications, as described in the TAIL-PCR protocol (Liu and Whittier (1995), Genomics, 25:674-681), DNA fragments are produced that correspond to the genomic DNA that is directly adjacent to the transposon or T-DNA insertion.

TAIL2k-PCR differs from the original TAIL-PCR protocol by the elimination of the 30 tertiary PCR and modification of the secondary PCR. The cycling conditions used in the secondary reaction are modified to include 5 high annealing temperature cycles (64 degrees C) at the beginning, three additional so-called super cycles, and five additional low annealing temperature cycles (44 degrees C) at the end of the reaction. The melting

- 28 and extension times are the same as all other TAIL-PCR reactions. Additionally, the reaction volume is increased to 40 microliters. The nucleic acid sequences of the PCR products from the secondary TAIL2k-PCR reactions are then determined by standard molecular biology techniques. The resulting sequences are analyzed for the presence of 5 non-De transposon or non-T-DNA vector sequence.

To confirm the integrity of the resultant products, PCR primers specific to the flanking genomic region are designed and used in conjunction with the tertiary nested primer in a PCR reaction, to confirm the transposon or T-DNA insertion point within the genomic DNA. Finding a PCR product of the appropriate size, based on the sequence of lo the TAIL2k-PCR sequencing result confimns a valid rescue.

Example 6: Identification of Both Borders of a T-DNA or Ds Insertion If the results of border rescue provide information on only one of the two borders 5 for an insertion in a given line, additional experiments are performed to identify the second border. These experiments are necessary to show that a single gene has been disrupted in a given line. In some cases, an insertion can affect more than a single gene due to a chromosomal deletion or rearrangement. In those cases, additional experiments are required to identify which of the affected genes is responsible for the lethal 20 phenotype.

When both borders of an insertion are not recovered, primers are designed to isolate a PCR product that will provide information on the location of the missing border.

Three primers are chosen in Arabidopsis genomic DNA on the opposite side of the insertion about one, two, and five kb away from the insertion point; the primers point 25 towards the expected second border. Long PCR conditions (Advantage 2, Clontech) are then employed following the manufacturer's directions to amplify the relevant region from genomic DNA isolated from a heterozygote for the lethal mutation. PCR reactions are performed using appropriate pairs of genomic and T-DNA or Ds border primers.

Finding a PCR product of the appropriate size, based on the sequence of the TAIL-PCR 30 clone confirms a valid rescue of the second border. In some cases, the PCR product is directly sequenced to determine the exact insertion point.

If the second border is not recovered with this method, an additional set of PCR reactions are preformed. In these experiments, the genomic primers are paired with a

- 29 series of internal T-DNA or Ds primers designed at about one kb intervals in both orientations across the entire T-DNA or Ds vector sequence. Finding a PCR product of the appropriate size, based on the sequence of the TAIL-PCR clone confirms a valid rescue of the second border. In some cases, the PCR product is directly sequenced to 5 determine the exact insertion point. Any borders recovered with this approach are classified as abnormal because they lack the ends of the Ds transposon or the expected 24 bp T-DNA imperfect repeat characteristic of right and left borders.

Example 7: Identification of Insertion Points for Lines with Lethal Phenotypes For each line with a lethal phenotype, the sequences of the borders of the insertion are determined and the insertion points in the Arabidopsis genome are deduced.

For Ds insertion lines, PCR products are obtained from the Ds3 and Ds5 borders. For T-

DNA lines, PCR products or plasmid rescue clones are obtained from left (LB), right Is (RB), or abnonnal (AB) borders. These sequences are used in BLASTn searches against nucleotide databases (Altschul et al. (1990) J Mol. Biol. 215:403-410; Altschul et al. (1997) Nucleic Acids Res. 25:33893402). The results are summarized in Table 4. Ds line names begin with ET or GT; T-DNA line names are numbers. The insertion point (Insert Pt.) and the direction of the flanking sequence (Dir.) either up (U) or down (D) in 20 the genome section is noted. Often, small deletions or duplications of genomic DNA accompany the insertion of a T-DNA or Ds transposon.

The gene that has been inactivated in a given line with a lethal phenotype is detennined from the insertion points for that line. Often, the precise location of an ORE for a given gene is not known, but predictions are available in genome sections deposited 2s in GenBank. The precise boundaries of that ORE is determined as described in Example 7. Table 4: Insertion Points For Lines With Lethal Phenotypes Gene Line # Border Genome Acc. # Insert Dir.

Section Pt. 148 ET7279 DS5 F15H18 AC013354 64874 U

148 ET7279 DS3 F15H18 AC013354 64877 D

_ 522 49488 RB ATCHRIV73 AL161577 79205 U

615 55514 LB T30B22 AC002535 69225 D

- 30 Gene Line # Border Genome Acc. # Insert Dir.

Section Pt. 615 55514 LB T30B22 AC002535 73124 U

677 54921 LB T10024 AC007067 43541 U

677 54921 AB T10024 AC007067 43499 D

917 45288 LB MYC6 AB006707 78749 D

917 288 RB MYC6 AB006707 78795 U

967 17535 LB ATCHRIV59 AL161559 17817 U

967 17535 RB ATCHRIV59 AL161559 17795 D

1032 32448 RB T32M21 AL162875 67960 U

1032 32448 LB T32M21 AL162875 67908 D

1032 40573 LB T32M21 AL162875 70692 D

1032 40573 AB T32M21 AL162875 70714 U

1036 42644 LB MYF24 AB026658 33222 U

1036 42644 LB MYF24 AB026658 33189 D

1113 50481 RB TlG16 AC069556 35878 U 1113 50481 LB TlG16 AC069556 35857 D 1408 125807 RB T5N23 AL138650 6910 D

1408 80750 LB T5N23 AL138650 5426 D

1408 80750 LB T5N23 AL138650 5436 U

1420 133038 RB ATCHRIV68 AL161572 106912 U

1420 39002 LB ATCHRIV68 AL161572 106125 U

1420 39002 AB ATCHRIV68 AL161572 106113 D

1542 1219_D08 LB K2I5 AB025613 35289 D

1542 1219_D08 RB K2I5 AB025613 35303 U

1542 56251 LB K2I5 AB025613 35675 U

1542 56251 LB K2I5 AB025613 35633 D

1578 84832 LB F7Gl9 AC000106 103707 U 1578 84832 LB F7Gl9 AC000106 103699 D 3284 48596 LB F21 03 AC009853 54820 U

3284 48596 AB F21 03 AC009853 54811 D

3741 39846 LB F2206 AL050300 3719 D

3741 39846 RB F2206 AL050300 5091 U

4390 114091 LB F14P3 AC009755 50045 D

4390 114091 LB F14P3 AC009755 50047 U

4818 104176 LB F24B22 AL132957 43616 D

4818 104176 RB F24B22 AL132957 43652 U

6916 124322 LB MKP6 AB022219 13829 U

6916 124322 LB MKP6 AB022219 13777 D

6952 96735 RB MKP6 AB022219 57551 D

6952 96735 LB MKP6 AB022219 57723 U

7044 24143 RB F27Kl9 AL163832 74211 U 7044 24143 LB F27Kl9 AL163832 73190 D 7427 121994 LB T21B14 AC069473 34366 D

7427 121994 LB T21B14 AC069473 34370 U

7553 66280 LB F24P17 AC011623 35002 D

8972 113422 LB Tl IA7 AC002339 75921 U 11151 84007 LB T13C7 AC007109 25528 D

- 31 Gene Line # Border Genome Acc. # Insert Dir.

Section Pt. 11151 84007 RB T13C7 AC007109 25553 U

11824 85225 RB T1E2 AC006929 74286 U

11824 85225 LB T1E2 AC006929 74261 D

12116 66202 LB T20B5 AC002409 47198 D

12931 78248 LB F5011 AC025416 52910 U

12931 78248 LB F5011 AC025416 52901 D

14280 103268 LB F5D14 AC007767 109164 D

14280 103268 LB F5D14 AC007767 109198 U

14645 60484 LB F7Al9 AC007576 82231 U 14645 60484 RB F7Al9 AC007576 82194 D 14752 73215 LB F20P5 AC002062 71790 D

14752 80413 LB F20P5 AC002062 71790 D

14752 80829 LB F20P5 AC002062 72318 D

14752 80829 RB F20P5 AC002062 72376 U

16998 20025 RB F15K9 AC005278 56964 D

16998 20025 _ LB F15K9 AC005278 56995 U

17459 50180 LB F3F9 AC013430 67834 D

17459 50180 LB F3F9 AC013430 67838 U

18065 70412 LB TlG11 AC002376 71929 D 18065 70412 RB TlG11 AC002376 71943 U 19230 102828 LB T21F11 AC018849 86749 U

19230 102828 LB T21F11 AC018849 86730 D

19634 71953 LB MCA23 AB016886 52875 U

19634 71953 LB MCA23 AB016886 52802 D

19634 75808 LB MCA23 AB016886 54634 D

19634 75808 LB MCA23 AB016886 54653 U

* 20287 120531 LB ATCHRIV85 AL161589 157523 D

20287 120531 LB ATCHRIV85 AL161589 157581 U

20967 132426 LB ATCHRIV79 AL161583 126497 D

20967 132426 RB ATCHRIV79 AL161583 126504 U

21709 122206 LB ATCHRIV39 AL161539 78197 U

21709 122206 RB ATCHRIV39 AL161539 78178 D

21709 130752 LB ATCHRIV39 AL161539 77967 D

21709 130752 LB ATCHRIV39 AL161539 77949 U

22867 129824 LB ATCHRIV70 AL161574 49176 D

22867 129824 RB ATCHRIV70 AL161574 49649 U

23084 87112 RB ATCHRIV71 AL161575 69902 D

23084 87112 RB ATCHRIV71 AL161575 69929 D

23644 105932 LB ATCHRIV78 AL161582 9334 D

23644 105932 LB ATCHRIV78 AL161582 9342 U

24150 28536 LB F8L15 AL392174 72429 U

24150 28536 LB F8L15 AL392174 72407 D

24370 117241 LB MJB21 AB007647 24031 D

24370 117241 RB MJB21 AB007647 24036 U

24793 110903 RB MIKl9 AB013392 23620 D

- 32 Gene Line # Border Genome Acc. # Insert Dir.

Section Pt. 24793 110903 RB Ml:Kl9 AB013392 23819 U 24801 127779 RB MIKl9 AB013392 36992 U 24801 127779 LB MIKl9 AB013392 36992 D 25704 92330 LB F12B17 AL353995 27534 U

25704 92330 LB F12B17 AL353995 27506 D

26379 132302 LB MCK7 AB019228 31105 U

26379 132302 LB MCK7 AB019228 30995 D

Example 8: Identification of cDNAs for Essential Genes 5 A cDNA for a gene identified as essential is identified using a variety of approaches. This information enables the ORF for a given gene to be identified and used for other experiments including expression of the corresponding protein in heterologous systems. If there is a full-length cDNA deposited in GenBank or published elsewhere, that 0 sequence may be checked independently using methods described below. Alternatively, the sequence may be considered to be correct.

In some cases, there are published EST sequences that can be assembled to cover the entire ORF from start codon to stop codon. This sequence may be checked independently using methods described below or it may be considered to be correct.

5 Often part of the cDNA is published and this information can be used to identify the entire ORF. If the 5' end containing the start codon is known, 3' RACE is performed to identify the remainder of the cDNA. If the 3' end containing the stop cation is known, 5' RACE is performed to identify the remainder of the cDNA. If both the 5' and the 3' ends are known, but the sequence between the two ends of the cDNA is not known, PCR 20 is performed with primers hybridizing to each end of the cDNA. In all three of these cases, PCR is performed using template DNA from a GeneRacer (Invitrogen) or a Marathon (Clontech) cDNA library prepared from RNA isolated from seedling tissue. A resulting PCR product is TA- cloned (Original TA-Cloning kit, Invitrogen) and sequenced. 2s If no part of the cDNA is published, the cDNA is identified by starting from gene model predictions in the annotation for genomic clones or elsewhere. To identify the ORF, primers are designed to the 5' and 3' ends of the predicted ORF. PCR is performed

- 33 using template DNA from a cDNA library prepared from seedling tissue or the pFL61 Arabidopsis cDNA library (Mines et al. (1992) Plant J. 2: 417-422). The resulting PCR product is TA-cloned (Original TA-Cloning kit, Invitrogen) and sequenced.

Alternatively, 5' and 3' RACE are performed with primers predicted by gene models to s be in exons. PCR is performed using template DNA from a GeneRacer (Invitrogen) or a Marathon (Clontech) cDNA library prepared from RNA isolated from seedling tissue. A resulting PCR product is TA- cloned (Original TA-Cloning kit, Invitrogen) and sequenced. If the cDNA sequence is the same as the sequence predicted in the GenBank 0 annotation, the experiments confirm for the first time the actual ORF. If the cDNA sequence is not the same as the sequence predicted in the GenBank annotation, the experiments identify for the first time the actual ORF. In some cases, more than one cDNA sequence is found for a given gene and both sequences are included in this application. Example 9: Description of Essential Genes

The putative function of the protein encoded by each essential gene is determined from analysis of the ORF in each cDNA. Information from the relevant Arabidopsis 20 genomic section deposited in GenBank is used as a starting point to explore the function of a given gene. This analysis also includes BLAST searches (Altschul et al. (1990) J. Mol. Biol. 215:403-410; Altschul et al. (1997) Nucleic Acids Res. 25:3389-3402) of sequence databases to identify similar proteins. Table 5 describes the putative functions for the essential genes discovered in this application.

2s Table 5: Putative Functions For Essential Genes GENE SEQ ID Putative Function & Similar References NO Genes 148 1-2 similar to RNA polymerase Albright, S.R. & Tjian, R. (2000) transcription initiation TFIIH Gene 242:1-13; Holstege, F.C. et (factor b) in fungi & animals al. (1998) Cell 95:717-728; Machida, M. et al. (2000) Yeast 16:71-80

- 34 GENE SEQ ID Putative Function & Similar References NO Genes 522 3- 4 most similar to Brassica napus Bourgis, F. et al. (1999) Plant Iysophosphatidic acid Physiol 120:913-922; Coleman, J. acyltransferase (ACT2); (1992) Mol Gen Genet 232:295 contains acyltransferase 303; Brown, A.P. et al. (1994) domain (PFAM 01553) Plant Mol Biol. 26:211-223 615 5- 6 Arabidopsis myb-related Stracke, R. et al. (2001) Curr Opin transcription factor MYB12, Plant Biol. 4:447-456; Jin, H. & similar to maize P Martin, C. (1999) Plant Mol Biol.

transcriptional regulator and 41:577-585; Grotewold E. et al. other R2R3 myb proteins (1991) Proc Natl Acad Sci USA 88:4587-4591

677 7-8 similar to Dictyostelium Bertin, J. et al. (1999) J Biol Chem discoideum deliriums ERR 274:12955-12958; Yaseen, N.R. & protein (AF272150.1), human Blobel, G. (1999) J Biol Chem caspase recruitment domain 274:26493-26502; Kalab, P. et al. protein 4 (Nodl), Arabidopsis (1999) Curr Biol 9:481-484; RAN GTPase activating Haberland, J. & Gerke, V. (1999) protein 1 & ribonuclease Biochem J. 343:653-662 nhbtors 917 9-10 Arabidopsis dihydrofolate Ravanel, S. et al. (2001) Proc. Natl. synthetase/folylpolyglutamate Acad. Sci. U.S.A. 98:15360-15365; synthetase dhfs/fpgsl gene Sheng, Y. et al. (2000) J Mol Biol, 302:427- 440.; Cherest, H. et al. (2000) J Biol Chem, 275:14056 14063; Sun, X. et al. (1998) Proc Natl Acad Sci USA, 95:6647-6652 967 11-12 Arabidopsis receptor-like Torii, K.U. (2000) Curr Opin Plant protein kinase (RKC1) gene, Biol 3:361-367; Ohtake, Y. et al. probable serine-threonine (2000) Plant Cell Physiol 41:1038 specific kinase, contains 2 1044 DUF26 domains (PFAM 01657)

1032 13-14 Arabidopsis Demeter, Choi, Y. et al. (2002) Cell 110:33 contains HhH-GPD DNA 42; Bruner, S.D. et al. (2000) glycosylase (PFAM 00730) Nature, 403:859-866; Hendrich, B. and nuclear localization et al. (1999) Nature, 401:301-304 domains 1036 15-16 similar to maize crsl nuclear Vogel, J. et al. (1999) Nucleic gene required for splicing of Acids Res, 27:3866-3874; Jenkins, the group II intron in B.D. et al. (1997) Plant Cell 9:283 chloroplast atpF gene; large 296 gene family in Arabidopsis 1113 17-18 similar to S. cerevisiae LSm4 Pannone, B.K. et al. (2001) & other U6 snRNA-associated Genetics 158:187-196; He, W. & Sm-like proteins involved in Parker, R. (2000) Curr Opin Cell pre-mRNA splicing Biol 12:346-350

- 35 GENE SEQ ID Putative Function & Similar References NO Genes 1408 1920 putative glutathione reductase, Lee, H. et al. (1998) Biochim chloroplast precursor Biophys Acta. 1395:309-314; Creissen, G.P. & Mullineauxm P.M. (1995) Planta 197:422-425; Creissen, G. et al. (1992) Plant J 2:129-131

1420 21-22 similar to human Jenne, D.E. et al. (2000) Genomics Hepatocellular carcinoma- 66:93-97 associated antigen 66 & S. cerevisiae UTP6, part of small (ribosomal) subunit (SSU) processosome (contains US snoRNA) 1542 23-24 Arabidopsis Korrigan, aka Nicol, F. et al. (1998) EMBO J. cellulase homolog OR16pep 17:5563-5576; Hrmova, M. et al. precursor, endo-1,4-beta-D- (2002) Plant Cell 14:1033-1052; glucanase Brurnmell, D.A. et al. (1997) Proc. Natl. Acad. Sci. USA 94:4794 1578 25-26 similar to rice unknown Michael, W.M. & Dreyfuss, G. function protein (1996) J Biol Chem 271:11571 (AAL79794.1), may contain 11574 Ribosomal L18p/L5e domain involved in binding 5S rRNA (PFAM 00861), member of small gene family in Arabidopsis 3284 27-28 unknown function, contains Massidda, O. et al. (1998) YGGT motif found in Microbiology 144:3069-3078 conserved hypothetical integral membrane proteins (PFAM 02325)

3741 29-30 Arabidopsis RNA-binding Ohta, M. et al. (1995) Plant Mol protein cp33 precursor, Biol 27:529-539; Li, Y.Q. & contains 2 RNA recognition Sugiura, M. (1990) EMBO J motifs (akaRRM, RBD, or 9:3059-3066; Li, Y. et al. (1993) RNP domains) (PFAM Mol Gen Genet 239:304-309; 00076) Birney, E. et al. (1993) Nucleic Acids Res 21:5803-5816 4390 31- 32 unknown function, similar to Walden, R. et al. (1994) EMBO J tobacco axil, contains 13:4729-4736; Schell, J. (1999) DUF246 domain (PFAM EMBO J 18:2908 (retraction) 03138), member of large gene family in Arabidopsis

- 36 GENE SEQ ID Putative Function & Similar References NO Genes 4818 3334 Arabidopsis FIP37, which Little, N.A. et al. (2000) Hum Mol binds the FKBP12 interacting Genet, 9:2231-2239; Penalva, L.O.

protein; also similar to mouse et al. (2000) Genetics, 155:129 Wilms' tumour 1-associating 139; Faure, J.D. et al. (1998) Plant protein (WTAP)and J 15:783-789 Drosophila fl(2)d 6916 35-36 Arabidopsis calcineurin Blike Shi, J. et al. (1999) Plant Cell Ca(2)+ binding protein(CBL)11:2393-2405; Albrecht, V. et al. interacting protein kinase 1 (2001) EMBO J. 20:1051-1063; (aka CIPK1), a putative Park,Y.S. et al.(l993) Plant Mol. serine/threonine kinase with a Biol. 22:615-624 NAF domain (PFAM 03822) 6952 37-38 similar to maize iron- Curie, C. et al. (2001) Nature phytosiderophore transporter 409:346-349; Yen, M.R. et al. protein yellow stripe 1, (2001) Microbiology 147:2881 member of gene family in 2883 Arabidopsis 7044 39-40 unknown function none 7427 41-42 contains MMR_HSR1, Vernet, C. et al. (1994) Mamm GTPase of unknown function Genome 5:100-105 domain (PFAM 01926) 7553 43-44 unknown function, similar to Bentolila, S. et al. (2002) Proc Natl petunia Rf-PPR592 fertility Acad Sci USA 99:10887-10892; restorer protein, contains 2 Small, I.D. & Peeters, N. (2000) PPR domains (PFAM 01535), Trends Biochem Sci 25:46-47; member of large gene family Fisk, D.G. et al. (1999) EMBO J in Arabidopsis 18:2621-2630; Coffin, J.W. (1997) Curr. Genet. 32:273-280 8972 45-46 unknown function, similar to Bentolila, S. et al. (2002) Proc Natl petunia Rf-PPR592 fertility Acad Sci USA 99:10887-10892; restorer protein, contains PPR Small, I.D. & Peeters, N. (2000) domains (PFAM 01535), Trends Biochem Sci 25:46-47; member of large gene family Fisk, D. G. et al. (1999) EMBO J in Arabidopsis 18:2621-2630; Coffin, J.W. (1997) Curr. Genet. 32:273-280 11151 47-48 similar to human & yeast Dez, C. et al. (2001) Nucleic Acids NOP10, required for pre- Res 29:598-603; Pogacic V, et al. rRNA pseudouridylation and (2000) Mol Cell Biol 20:9028 processing at sites A1 and A2 9040; Lafontaine, D.L. & Tollervey, D (1998) Trends Biochem Sci 23:383-388 _ 11824 49-50 serine carboxypeptidase-like Liao, D.I. & Remington, S.J.

(1990) J Biol Chem 265:6528 6531; Ostrowska, H. & Gacko, M. (1998) Rocz Akad Med Bialymst 43:39-55; Remington, S.J. (1993) Curr Opin Biotechnol 4:462-468

- 37 GENE SEQ ID Putative Function & Similar References NO Genes 12116 51 -52 Arabidopsis ubiquitin-specific Rao-Naik, C. et al. (2000) Arch protease 5 (AtUBP5) Biochem Biophys 379:198-208; Glickman, M.H. &Ciechanover, A. (2002) Physiol Rev. 82:373-428; Doelling, J.H. et al. (2001) Plant J. 27:393-405

12931 53-54 Arabidopsis nClpP2, an ATP- Nakabayashi, K. et al. (1999) Plant dependent Clp protease Cell Physiol. 40:504-514; proteolytic subunit (ClpR2) Porankiewicz, J. et al. (1999) Mol Microbiol. 32:449-458; Adam Z. (2000) Biochimie 82:647-654 14280 55-56 similar to putative pre- mRNA Lundgren, K. et al. (1996) Mol splicing factorATP- Biol Cell 7:1083- 1094; Company, dependent RNA helicases M. et al. (1991) Nature 349:487 such as C. elegans mog-4 & 493; Caruthers, J.M. & McKay, mog-5, S. cerevisiae prp22, D.B. (2002) Curr Opin Struct Biol and S. pombe cdc28 12:123-133; Li, S.C. et al. (2001) Plant Mol Biol 47:761-770; Boudet, N. et al. (2001) Genome Res 11:2101-2114 14645 57-58 similar to ribulose-1,5 Ying, Z. et al. (1996) Plant Mol bisphosphate carboxylase Biol. 32:663- 671; Wang, Y.L. et al. oxygenase large and small (2001) Arch Biochem Biophys.

subunit N-methyltransferases 396:35-42 14752 59-60 similar to DEAD/DEAH box de la Cruz J. et al. (1998) EMBO J ATP-dependent RNA 17:1128-1140; Widner, W.R. & helicases including S. Wickner, R.B. (1993) Mol Cell cerevisiae DOB1 (mRNA Biol 13:4331-4341; de la Cruz J. et transport regulator MTR4) & al. (1999) Trends Biochem Sci. SKI2 antiviral protein which 24:192-198 represses dsRNA virus propagation 16998 61-62 similar to mammalian Murray, J.M. et al. (1992) Nucleic nucleotide excision repair Acids Res. 20:2673-2678; Prakash, protein (ERCC2, Xeroderma S. & Prakash, L. (2000) Mutat Res. pigmentosum group D), S. 451:13-24; Friedberg, E.C. (1991) cerevisiae Rad3, S. pombe Mol Microbiol. 5:2303-2310 Radl5 17459 63-64 similar to serine-threonine Holappa, L.D. & Walker-Simmons, protein kineses, including M.K. (1997) Plant Mol. Biol.

grape GDBrPK 33:935-941; Park,Y.S. et al.(l993) (AAG31326.1) and wheat Plant Mol. Biol. 22:615-624; TaPK3 (AAB58348.1); Sugden C. et al. (1999) Plant J. member of large gene family 19:433-439; Ohba, H. et al. (2000) in Arabidopsis Mol Gen Genet. 263:359-366

- 38 GENE SEQ ID Putative Function & Similar References NO Genes 18065 6566 unknown function protein, none member of small gene family in Arabidopsis 19230 67-68 similar to N-terminal Lee, F.J. et al (1989) J. Biol. Chem. acetyltransferases, including 264:12339-12343; Bradshaw, R.A.

S. cerevisiae NAT1 & mouse et al. (1998) Trends Biochem Sci. Tubedown-1 23:263-267; Driessen, H.P. et al. (1985) CRC Crit Rev Biochem. 18:281-325

19634 69-70 similar to adenylate kineses, Schiltz, E. et al. (1994) Eur. J. including maize ADK1 & E. Biochem. 222:949-954; Wild, K. et cold Adk al. (1997) Eur. J. Biochem. 250:326-331

20287 71-72 similar to S. cerevisiae & Caplan, S. et al. (2001) J. Cell Biol mammalian Vps39/Vam6, a 154: 109-121; Nakamura, N. et al. carboxypeptidase required for (1997) J Biol Chem 272:11344 vacuolar morphogenesis, 11349; Huang, L. et al. (1999) Nat mouse pallidin, which Genet. 23:329-332 interacts w/syntaxin 13; may contain CNH domain (PFAM 00780)

20967 73-74 putative ABC transporter Stacey, G. et al. (2002) Trends Plant Sci. 7:257-263; Nikaido, H. (2002) Proc Natl Acad Sci USA 99:9609- 9610; Wolfger, H. et al. (2001) Res Microbiol. 152:375 389; Fath, M.J. & Kolter, R. (1993) Microbiol Rev. 57:995-1017 21709 75-76 unknown function none 22867 77-78 similar to EF-Ts translation BycorPt, M. et al. (1997) Cell 88: elongation factors and 235-242; Nesper, M. et al. (1998) contains two S1 RNA binding Eur J Biochem 255:81-86; Wieden, domains H.J. et al. (2002) J Biol Chem 277:6032-6036

23084 79-80 unknown function none 23644 81-82 similar to RNA-binding LinMarq, N. & Clarkson, S.G.

proteins that bind to (1995) J Mol Biol 245: 81-85; Yoo, precursors of Pol III RNAs, C. J. & Wolin, S.L. (1994) Mol including S. cerevisiae LAH1, Cell Biol 14:5412-5424; Birney, E. human systemic lupus et al. (1993) Nucleic Acids Res erythematosus-associated 21:5803-5816 La/SS-B autoantigen, & D. melanogaster La homolog 24150 83-84 similar to unknown function none proteins in Arabidopsis, rice, & Synechocystis

- 39 GENE SEQ ID Putative Function & Similar References NO Genes 24370 8586 unknown function protein, none member of large Arabidopsis _ gene family 24793 87-88 putative pyrophosphate- Theodorou, M.E. & Kruger, N.J.

dependent phosphobructo-1- (2001) Planta 213:147-157; kinase (aka Shirakihara, Y. & Evans, P.R.

phosphoLructokinase) (1988) J Mol Biol 204:973-994 24801 89-90 putative cytosolic asparaginyl- Mucha, P. (2002) Acta Biochim tRNA synthetase (SYNC1) Pol 49:1-10; Peelers, N.M. et al. (2000) J Mol Evol 50:413-423; Aubourg, S. et al. (1998) Biochim BiophysActa, 1398:225-231 25704 91- 92 similar to putative plant & Sunna, A. & Antranikian, G. fungal beta-Dxylosidases; (1997) Crit Rev Biotechnol. 17:39 slightly less similar to 67; Hrmova, M. et al. (2002) Plant bacterial beta-glucosidases Cell 14: 1033 - 1052 26379 93-94 contains 5 WD-40 repeats; Ach, R.A. et al. (1997) Plant Cell similar to yeast MSI1 and 9:1595-1606; Qian, Y.W. & Lee, human Retinoblastoma E.Y. (1995) J Biol Chem binding proteins p46 & p48 270:25507-25513 (RbAp46 & RbAp48), which control G1/S transition Example 10: Expression of Recombinant Essential Proteins in E. cold s The coding region of each of the essential proteins, corresponding to cDNA clones of odd-numbered SEQ ID NO: 1 -96, is subcloned into an appropriate expression vector, and transformed into E. cold using the manufacturer's conditions. Specific examples include plasmids such as pBluescript (Stratagene, La Jolla, CA), pFLAG (International Biotechnologies, Inc., New Haven, CT), and pTrcHis (Invitrogen, La Jolla, o CA). E. cold is cultured, and expression of the essential protein is confirmed.

Recombinant protein is isolated using standard techniques.

Example I 1: In Vitro Binding Assays 5 Recombinant protein for each of the essential genes described in this application is obtained, for example, according to Example 10. The protein is immobilized on chips appropriate for ligand binding assays using techniques that are well known in the art.

- 40 The protein immobilized on the chip is exposed to sample compound in solution according to methods well know in the art. While the sample compound is in contact with the immobilized protein, measurements capable of detecting protein-ligand interactions are conducted. Examples of such measurements are SELDI, biacore and s FCS, described above. Compounds found to bind the protein are readily discovered in this fashion and are subjected to further characterization.

The above-disclosed embodiments are illustrative. This disclosure of the

invention will place one skilled in the art in possession of many variations of the 10 invention. All such obvious and foreseeable variations are intended to be encompassed by the present invention.

-41 SEQUENCE LISTING

<110> Levin, Joshua Z Patton, David McElver, John Zhou, Qing Aux, George W Tossberg, John Ashby, Carl Budziszewski, Gregory W <120> Nucleic Acid Molecules Encoding Proteins Essential for Plant Growth and Development and Uses Thereof <130> 70021

<160> 119

<170> PatentIn version 3.1 <210> 1

<211> 906

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(906)

<223> <400> 1

ate act gcc att get tat aag cag tat lea gac get gtt agt ctt cta Met Pro Ala Ile Ala Ser Lys Gin Tyr Ser Asp Asp Val Ser Leu Leu 1 5 10 15

-42 gtt ttg ttg ctt get acg eat cat ctt ttc tgg agc act ace leg att Val Leu Leu Leu Asp Thr Asn Pro Leu Phe Trp Ser Thr Thr Ser Ile 20 25 30

acc ttc tat cag ttc ctt let cat gtg ctt gcg ttt ctt eat gcg gtt Thr Phe Ser Gln Phe Leu Ser His Val Leu Ala Phe Leu Asn Ala Val 35 40 45

ttg ggg tta eat cag ttg aac caa gtt gta gUt ata gct act gga tac Leu Gly Leu Asn Gln Leu Asn Gln Val Val Val Ile Ala Thr Gly Tyr 50 55 60

agt let tgt get tac att tat get leg let ttg ace lea eat cat gga Ser Ser Cys Asp Tyr Ile Tyr Asp Ser Ser Leu Thr Ser Asn His Gly 65 70 75 80

eat ttc gag agc eat gga act gga atg cct goa att ttt ggt tat ttg Asn Phe Glu Ser Asn Gly Thr Gly Met Pro Ala Ile Phe Gly Ser Leu 85 90 95

ctt aag aaa ttg gaa gag tUt gtt acc aaa get gag gag ctc agc aag Leu Lys Lys Leu Glu Glu Phe Val Thr Lys Asp Glu Glu Leu Ser Lys 100 105 110

gag gaa gtg tat gag get age ata cat tat tgt ctc ttg lea gga lea Glu Glu Val Ser Glu Asp Arg Ile Pro Ser Cys Leu Leu Ser Gly Ser 115 120 125

ctc tcc atg get cUt tgc tat ata cag agg gtt ttc cgt tat gga cat Leu Ser Met Ala Leu Cys Tyr Ile Gln Arg Val Phe Arg Ser Gly His 130 135 140

cht cat cac cag cct cgg att tta tgc ttg caa ggt tcc cca get ggc Leu His Pro Gln Pro Arg Ile Leu Cys Leu Gln Gly Ser Pro Asp Gly 145 150 155 160

ccg gaa cag tat gUt get ght aLg aac tat ale tEc let gac caa cgc Pro Glu Gln Tyr Val Ala Val Met Asn Ser Ile Phe Ser Ala Gln Arg 165 170 175

-43 ttg atg gtt cac att get leg tgt tac ata ggt gta cag aac lea gca Leu Met Val Pro Ile Asp Ser Cys Tyr Ile Gly Val Gln Asn Ser Ala 180 185 190

ttt ttg cag cag gca let tat ata act ggt ggt gta cat cat ace cct Phe Leu Gln Gln Ala Ser Tyr Ile Thr Gly Gly Val His His Thr Pro 195 200 205

aaa cag ttg get ggg cta ttt caa tat cta acg ace ale ttt gca acc Lys Gln Leu Asp Gly Leu Phe Gln Tyr Leu Thr Thr Ile Phe Ala Thr 210 215 220

get ttg cac tcc cgc ggt ttt gta caa ctt cct aaa ccc ata ggt gta Asp Leu His Ser Arg Gly Phe Val Gln Leu Pro Lys Pro Ile Gly Val 225 230 235 240

get ttt cgc gca leg tgc ttt tgc cac aag aag ace ata get atg ggc Asp Phe Arg Ala Ser Cys Phe Cys His Lys Lys Thr Ile Asp Met Gly 245 250 255

tac ata tgc lea gtg tgt ctg tcc att thc tgt gag cat cac aag aaa Tyr Ile Cys Ser Val Cys Leu Ser Ile Phe Cys Glu His His Lys Lys 260 265 270

tgt lea acc tgc ggg let gLa ttt ggt cag let aaa ctt get get get Cys Ser Thr Cys Gly Ser Val Phe Gly Gln Ser Lys Leu Asp Asp Ala 275 280 285

lea tat gac let get aag aag age aaa gct cct agt acc tea Ser Ser Ala Ser Asp Lys Lys Arg Lys Ala Pro Ser Thr 290 295 300

<210> 2

<211> 301

<212> PRT

<213> Arabidopsis thaliana

-44 <400> 2

Met Pro Ala Ile Ala Ser Lys Gln Tyr Ser Asp Asp Val Ser Leu Leu 1 5 10 15

Val Leu Leu Leu Asp Thr Asn Pro Leu Phe Trp Ser Thr Thr Ser Ile 20 25 30

Thr Phe Ser Gln Phe Leu Ser His Val Leu Ala Phe Leu Asn Ala Val 35 40 45

Leu Gly Leu Asn Gln Leu Asn Gln Val Val Val Ile Ala Thr Gly Tyr 50 55 60

Ser Ser Cys Asp Tyr Ile Tyr Asp Ser Ser Leu Thr Ser Asn His Gly 65 70 75 80

Asn Phe Glu Ser Asn Gly Thr Gly Met Pro Ala Ile Phe Gly Ser Leu 85 90 95

Leu Lys Lys Leu Glu Glu Phe Val Thr Lys Asp Glu Glu Leu Ser Lys 100 105 110

Glu Glu Val Ser Glu Asp Arg Ile Pro Ser Cys Leu Leu Ser Gly Ser 115 120 125

Leu Ser Met Ala Leu Cys Tyr Ile Gln Arg Val Phe Arg Ser Gly His 130 135 140

Leu His Pro Gln Pro Arg Ile Leu Cys Leu Gln Gly Ser Pro Asp Gly 145 150 155 160

Pro Glu Gln Tyr Val Ala Val Met Asn Ser Ile Phe Ser Ala Gln Arg 165 170 175

Leu Met Val Pro Ile Asp Ser Cys Tyr Ile Gly Val Gln Asn Ser Ala 180 185 190

-45 Phe Leu Gln Gln Ala Ser Tyr Ile Thr Gly Gly Val His His Thr Pro 195 200 205

Lys Gln Leu Asp Gly Leu Phe Gln Tyr Leu Thr Thr Ile Phe Ala Thr 210 215 220

Asp Leu His Ser Arg Gly Phe Val Gln Leu Pro Lys Pro Ile Gly Val 225 230 235 240

Asp Phe Arg Ala Ser Cys Phe Cys HiS Lys Lys Thr Ile Asp Met Gly 245 250 255

Tyr Ile Cys Ser Val Cys Leu Ser Ile Phe Cys Glu His His Lys Lys 260 265 270

Cys Ser Thr Cys Gly Ser Val Phe Gly Gln Ser Lys Leu Asp Asp Ala 275 280 285

Ser Ser Ala Ser Asp Lys Lys Arg Lys Ala Pro Ser Thr 290 295 300

<210> 3

<211> 1071

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1071)

<223>

-46 c400> 3 atg get gtc gct let gct cgg agc ale let lea cat cct lea tat tat Met Asp Val Ala Ser Ala Arg Ser Ile Ser Ser His Pro Ser Tyr Tyr 1 5 10 15

gga aaa ccg att tgt lea lea caa lea leg ttg att cgg att tag agg Gly Lys Pro Ile Cys Ser Ser Gln Ser Ser Leu Ile Arg Ile Ser Arg 20 25 30

get aaa ght tgt tgc ttt ggt cgc att let eat ggc atg acg agc tUt Asp Lys Val Cys Cys Phe Gly Arg Ile Ser Asn Gly Met Thr Ser Phe 35 40 45

act act tcc ctt cat gct gtc ccg agt gaa aaa ttt atg ggc gaa ace Thr Thr Ser Leu His Ala Val Pro Ser Glu Lys Phe Met Gly Glu Thr 50 55 60

age cgt act ggc att caa tgg tat aac cgc tat tta age cat get cct Arg Arg Thr Gly Ile Gln Trp Ser Asn Arg Ser Leu Arg His Asp Pro 65 70 75 80

tac age tUt ctt get aag aaa lea cct age lea agt caa ttg gca age Tyr Arg Phe Leu Asp Lys Lys Ser Pro Arg Ser Ser Gln Leu Ala Arg 85 90 95

get ale act gtg age gca get ctt lea gga gct gca acc cct gac let Asp Ile Thr Val Arg Ala Asp Leu Ser Gly Ala Ala Thr Pro Asp Ser 100 105 110

let ttt cct gaa cca gag att aag ttg agc lea age ctc age ggg ata Ser Phe Pro Glu Pro Glu Ile Lys Leu Ser Ser Arg Leu Arg Gly Ile 115 120 125

tUc ttt tgt gtt gEt get ggc att leg get act ttt ctc att gtc ctg Phe Phe Cys Val Val Ala Gly Ile Ser Ala Thr Phe Leu Ile Val Leu 130 135 140

aLg att att ggg cat cag ttc gEc ctt ctc tEc get ccc tat agg age Met Ile Ile Gly His Pro Phe Val Leu Leu Phe Asp Pro Tyr Arg Arg 145 150 155 160

-47 aaa ttc cac cac ttc att gat aaa cht tgg gct tcc ata agc att tat Lys Phe His His Phe Ile Ala Lys Leu Trp Ala Ser Ile Ser Ile Tyr 165 170 175

ccg ttt tac aaa atc aac atc gag ggt ttg gag aat ctg cca tca tca Pro Phe Tyr Lys Ile Asn Ile Glu Gly Leu Glu Asn Leu Pro Ser Ser 180 185 190

gac act cat gct gta tat gtt tca aac cac caa agt ttt ctg gat atc Asp Thr Pro Ala Val Tyr Val Ser Asn His Gln Ser Phe Leu Asp Ile 195 200 205

tac aca ctt cht agt ctt gga aaa agc ttt aag ttc atc agc aag aca Tyr Thr Leu Leu Ser Leu Gly Lys Ser Phe Lys Phe Ile Ser Lys Thr 210 215 220

ggg ata ttc gta att cac atc atc ggt tgg gcc aUg tcc aLg atg ggt Gly Ile Phe Val Ile Pro Ile Ile Gly Trp Ala Met Ser Met Met Gly 225 230 235 240

gtc gtt cac ttg aag cgg atg gac cca aga agc caa gtg gat tgc tta Val Val Pro Leu Lys Arg Met Asp Pro Arg Ser Gln Val Asp Cys Leu 245 250 255

aaa cgc tgc atg gaa ctt tta aag aag gga goa tat gtg ttt ttc ttc Lys Arg Cys Met Glu Leu Leu Lys Lys Gly Ala Ser Val Phe Phe Phe 260 265 270

cca gaa gga aca cgg agt aag gat ggt cgg tta ggt tct ttc aag aaa Pro Glu Gly Thr Arg Ser Lys Asp Gly Arg Leu Gly Ser Phe Lys Lys 275 280 285

ggc gca ttt aca gUg gat gcg aag acc gga ght goa gta gUt cca ata Gly Ala Phe Thr Val Ala Ala Lys Thr Gly Val Ala Val Val Pro Ile 290 295 300

acg cta atg gga aca ggc aaa atc atg cca acg ggt agt gaa ggt ata Thr Leu Met Gly Thr Gly Lys Ile Met Pro Thr Gly Ser Glu Gly Ile 305 310 315 320

-48 ctg aac cat ggg eat gtg age gtt ale ale cat aaa cca ata cat gga Leu Asn His Gly Asn Val Arg Val Ile Ile His Lys Pro Ile His Gly 325 330 335

agc aaa gcg get gtt cUt tgc aac gag gac age agc aag att gca gaa Ser Lys Ala Asp Val Leu Cys Asn Glu Ala Arg Ser Lys Ile Ala Glu 340 345 350

lea atg get ctc tea Ser Met Asp Leu <210> 4

c211> 356 <212> PRT

<213> Arabidopsis thaliana <400> 4

Met Asp Val Ala Ser Ala Arg Ser Ile Ser Ser His Pro Ser Tyr Tyr 1 5 10 15

Gly Lys Pro Ile Cys Ser Ser Gln Ser Ser Leu Ile Arg Ile Ser Arg 20 25 30

Asp Lys Val Cys Cys Phe Gly Arg Ile Ser Asn Gly Met Thr Ser Phe 35 40 45

Thr Thr Ser Leu His Ala Val Pro Ser Glu Lys Phe Met Gly Glu Thr 50 55 60

Arg Arg Thr Gly Ile Gln Trp Ser Asn Arg Ser Leu Arg His Asp Pro 65 70 75 80

Tyr Arg Phe Leu Asp Lys Lys Ser Pro Arg Ser Ser Gln Leu Ala Arg

-49 85 90 95

Asp Ile Thr Val Arg Ala Asp Leu Ser Gly Ala Ala Thr Pro Asp Ser 100 105 110

Ser Phe Pro Glu Pro Glu Ile Lys Leu Ser Ser Arg Leu Arg Gly Ile 115 120 125

Phe Phe Cys Val Val Ala Gly Ile Ser Ala Thr Phe Leu Ile Val Leu 130 135 140

Met Ile Ile Gly His Pro Phe Val Leu Leu Phe Asp Pro Tyr Arg Arg 145 150 155 160

Lys Phe His His Phe Ile Ala Lys Leu Trp Ala Ser Ile Ser Ile Tyr 165 170 175

Pro Phe Tyr Lys Ile Asn Ile Glu Gly Leu Glu Asn Leu Pro Ser Ser 180 185 190

Asp Thr Pro Ala Val Tyr Val Ser Asn His Gln Ser Phe Leu Asp Ile 195 200 205

Tyr Thr Leu Leu Ser Leu Gly Lys Ser Phe Lys Phe Ile Ser Lys Thr 210 215 220

Gly Ile Phe Val Ile Pro Ile Ile Gly Trp Ala Met Ser Met Met Gly 225 230 235 240

Val Val Pro Leu Lys Arg Met Asp Pro Arg Ser Gln Val Asp Cys Leu 245 250 255

Lys Arg Cys Met Glu Leu Leu Lys Lys Gly Ala Ser Val Phe Phe Phe 260 265 270

Pro Glu Gly Thr Arg Ser Lys Asp Gly Arg Leu Gly Ser Phe Lys Lys 275 280 285

-50 Gly Ala Phe Thr Val Ala Ala Lys Thr Gly Val Ala Val Val Pro Ile 290 295 300

Thr Leu Met Gly Thr Gly Lys Ile Met Pro Thr Gly Ser Glu Gly Ile 305 310 315 320

Leu Asn His Gly Asn Val Arg Val Ile Ile His Lys Pro Ile His Gly 325 330 335

Ser Lys Ala Asp Val Leu Cys Asn Glu Ala Arg Ser Lys Ile Ala Glu 340 345 350

Ser Met Asp Leu <210> 5

<211> 1116

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1116)

<223> <400> 5

atg gga age gag cca tgt tgc gag aag gtc ggt ale aag age ggg cgg Met Gly Arg Ala Pro Cys Cys Glu Lys Val Gly Ile Lys Arg Gly Arg 1 5 10 15

tgg acg gcg gag gag gac cag att ctc tcc aac tac att caa tcc aac Trp Thr Ala Glu Glu Asp Gln Ile Leu Ser Asn Tyr Ile Gln Ser Asn

-51 20 25 30

ggt gaa ggt tat tgg age let ctc cac aaa eat gcc gga tta aaa agg Gly Glu Gly Ser Trp Arg Ser Leu Pro Lys Asn Ala Gly Leu Lys Arg 35 40 45

tgt gga aag agc tgt age ttg age tgg ata aac tat cta age lea gac Cys Gly Lys Ser Cys Arg Leu Arg Trp Ile Asn Tyr Leu Arg Ser Asp 50 55 60

ctc aag cgt gga aac ata act cca gaa gaa gaa gaa ctc gtt gtt aaa Leu Lys Arg Gly Asn Ile Thr Pro Glu Glu Glu Glu Leu Val Val Lys 65 70 75 80

ttg cat tcc act ttg gga aac agg tgg lea cta ale gcg ggt cat cta Leu His Ser Thr Leu Gly Asn Arg Trp Ser Leu Ile Ala Gly His Leu 85 90 95

cca ggg age ace gac aac gaa ata aaa eat tat tgg aac tat cat ctc Pro Gly Arg Thr Asp Asn Glu Ile Lys Asn Tyr Trp Asn Ser His Leu 100 105 110

agc cgt aaa ctc cac aac ttc att agg aag cca tcc ale let caa gac Ser Arg Lys Leu His Asn Phe Ile Arg Lys Pro Ser Ile Ser Gln Asp 115 120 125

gtc tcc gcc gta ale aLg acg aac gct let lea gag cca cag cag ccg Val Ser Ala Val Ile Met Thr Asn Ala Ser Ser Ala Pro Pro Pro Pro 130 135 140

cag gca aaa cgc age ctt ggg age acg agt agg tcc get atg aaa cca Gln Ala Lys Arg Arg Leu Gly Arg Thr Ser Arg Ser Ala Met Lys Pro 145 150 155 160

aaa ale cac age ace aaa act cgt aaa acg aag aaa aeg tat goa cca Lys Ile His Arg Thr Lys Thr Arg Lys Thr Lys Lys Thr Ser Ala Pro 165 170 175

ccg gag cct aac gac get gta get ggg get get aaa gaa goa tta atg Pro Glu Pro Asn Ala Asp Val Ala Gly Ala Asp Lys Glu Ala Leu Met

-52 180 185 190

gtg gag lea agt gga gac gag gct gag cta gga cga cca tgt gac tac Val Glu Ser Ser Gly Ala Glu Ala Glu Leu Gly Arg Pro Cys Asp Tyr 195 200 205

tat gga get get tgt aac aaa eat ctc aUg agc att eat ggc get eat Tyr Gly Asp Asp Cys Asn Lys Asn Leu Met Ser Ile Asn Gly Asp Asn 210 215 220

gga gtt tta acg ttt get get get ale ale get ctt ttg ttg gac gag Gly Val Leu Thr Phe Asp Asp Asp Ile Ile Asp Leu Leu Leu Asp Glu 225 230 235 240

lea get cct ggc cac ttg tac ace aac ace acg tgc ggt ggt get ggg Ser Asp Pro Gly His Leu Tyr Thr Asn Thr Thr Cys Gly Gly Asp Gly 245 250 255

gag ttg cat aac ata age gac let gaa gga gcc age ggg ttc leg get Glu Leu His Asn Ile Arg Asp Ser Glu Gly Ala Arg Gly Phe Ser Asp 260 265 270

act tgg aac caa ggg eat ctc gac tgt ctt ctt cag let tgt cca leg Thr Trp Asn Gln Gly Asn Leu Asp Cys Leu Leu Gln Ser Cys Pro Ser 275 280 285

gtg gag leg tht ctc aac tac gac cac caa gtt aac get gcg tag acg Val Glu Ser Phe Leu Asn Tyr Asp His Gln Val Asn Asp Ala Ser Thr 290 295 300

get gag ttt ale get tgg get tgt gtt tgg caa gaa ggt agt get eat Asp Glu Phe Ile Asp Trp Asp Cys Val Trp Gln Glu Gly Ser Asp Asn 305 310 315 320

eat ctt tgg cat gag aaa gag eat ccc gac lea aLg gtc leg tgg ctt Asn Leu Trp His Glu Lys Glu Asn Pro Asp Ser Met Val Ser Trp Leu 325 330 335

tta gac ggt get get gag gac aeg ale ggg eat agt eat tgt gag aac Leu Asp Gly Asp Asp Glu Ala Thr Ile Gly Asn Ser Asn Cys Glu Asn

-53 340 345 350

ttt gga gaa ccg tta get cat gac gac gaa agc get ttg gtc gct tgg Phe Gly Glu Pro Leu Asp His Asp Asp Glu Ser Ala Leu Val Ala Trp 355 360 365

ctt ctg lea tga Leu Leu Ser <210> 6

<211> 371

<212> PRT

<213> Arabidopsis thaliana <400> 6

Met Gly Arg Ala Pro Cys Cys Glu Lys Val Gly Ile Lys Arg Gly Arg 1 5 10 15

Trp Thr Ala Glu Glu Asp Gln Ile Leu Ser Asn Tyr Ile Gln Ser Asn 20 25 30

Gly Glu Gly Ser Trp Arg Ser Leu Pro Lys Asn Ala Gly Leu Lys Arg 35 40 45

Cys Gly Lys Ser Cys Arg Leu Arg Trp Ile Asn Tyr Leu Arg Ser Asp 50 55 60

Leu Lys Arg Gly Asn Ile Thr Pro Glu Glu Glu Glu Leu Val Val Lys 65 70 75 80

Leu His Ser Thr Leu Gly Asn Arg Trp Ser Leu Ile Ala Gly His Leu 85 90 95

Pro Gly Arg Thr Asp Asn Glu Ile Lys Asn Tyr Trp Asn Ser His Leu

-54 100 105 110

Ser Arg Lys Leu His Asn Phe Ile Arg Lys Pro Ser Ile Ser Gln Asp 115 120 125

Val Ser Ala Val Ile Met Thr Asn Ala Ser Ser Ala Pro Pro Pro Pro 130 135 140

Gln Ala Lys Arg Arg Leu Gly Arg Thr Ser Arg Ser Ala Met Lys Pro 145 150 155 160

Lys Ile His Arg Thr Lys Thr Arg Lys Thr Lys Lys Thr Ser Ala Pro 165 170 175

Pro Glu Pro Asn Ala Asp Val Ala Gly Ala Asp Lys Glu Ala Leu Met 180 185 190

Val Glu Ser Ser Gly Ala Glu Ala Glu Leu Gly Arg Pro Cys Asp Tyr 195 200 205

Tyr Gly Asp Asp Cys Asn Lys Asn Leu Met Ser Ile Asn Gly Asp Asn 210 215 220

Gly Val Leu Thr Phe Asp Asp Asp Ile Ile Asp Leu Leu Leu Asp Glu 225 230 235 240

Ser Asp Pro Gly His Leu Tyr Thr Asn Thr Thr Cys Gly Gly Asp Gly 245 250 255

Glu Leu His Asn Ile Arg Asp Ser Glu Gly Ala Arg Gly Phe Ser Asp 260 265 270

Thr Trp Asn Gln Gly Asn Leu Asp Cys Leu Leu Gln Ser Cys Pro Ser 275 280 285

Val Glu Ser Phe Leu Asn Tyr Asp His Gln Val Asn Asp Ala Ser Thr 290 295 300

-55 Asp Glu Phe Ile Asp Trp Asp Cys Val Trp Gln Glu Gly Ser Asp Asn 305 310 315 320

Asn Leu Trp His Glu Lys Glu Asn Pro Asp Ser Met Val Ser Trp Leu 325 330 335

Leu Asp Gly Asp Asp Glu Ala Thr Ile Gly Asn Ser Asn Cys Glu Asn 340 345 350

Phe Gly Glu Pro Leu Asp His Asp Asp Glu Ser Ala Leu Val Ala Trp 355 360 365

Leu Leu Ser <210> 7

<211> 1818

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1818)

<223> <400> 7

atg gct tat tat tcc acc agc tcc ctc eat ctc cac tat ctc ccc aag Met Ala Ser Ser Ser Thr Ser Ser Leu Asn Leu His Ser Leu Pro Lys 1 5 10 15

gct let tat ggg ttg ggc caa tgg aag agt ggg ttc cgg tac gaa ttg Ala Ser Ser Gly Leu Gly Gln Trp Lys Ser Gly Phe Arg Tyr Glu Leu

-56 20 25 30

ttg ggt agc tcc gtt tct agg aac cga ttg tht gtt tct cct gtg gtg Leu Gly Ser Ser Val Ser Arg Asn Arg Leu Phe Val Ser Pro Val Val 35 40 45

att cat cac cga agt ccg aga ctt ccg gcg atc aaa gcg gag tat aac Ile His His Arg Ser Pro Arg Leu Pro Ala Ile Lys Ala Ala Tyr Asn 50 55 60

tca gat gga ggc tcg aag cgt agt agg ght tat aag gag tca caa gcg Ser Asp Gly Gly Ser Lys Arg Ser Arg Val Tyr Lys Glu Ser Gln Ala 65 70 75 80

gat agt ggt ttt cct aat gct aaa gtg cag cag att gcg tct tcc gtc Ala Ser Gly Phe Pro Asn Ala Lys Val Gln Gln Ile Ala Ser Ser Val 85 90 95

ttg cac ttg gga tca tUt gct gtc gtc act ttc gtt ttg tgg aaa gtg Leu Pro Leu Gly Ser Phe Ala Val Val Thr Phe Val Leu Trp Lys Val 100 105 110

* ght ggg aag ttc atg tcg cat aag tct cca aag act tat gat gga gaa Val Gly Lys Phe Met Ser Pro Lys Ser Pro Lys Thr Ser Ala Gly Glu 115 120 125

aac aac tct tct aca cag gga gUg aaa tgg tag atc ggg gcc ggt act Asn Asn Ser Ser Thr Gln Gly Val Lys Trp Ser Ile Gly Ala Gly Thr 130 135 140

aat ttg tta caa gga ttt gct gct aag gtt gat aga gag gac aag cag Asn Leu Leu Gln Gly Phe Ala Ala Lys Val Asp Arg Glu Ala Lys Gln 145 150 155 160

agg cUt aat gaa ttt goa aaa gaa cEt agg tcc ttc aga agt ght gac Arg Leu Asn Glu Phe Ala Lys Glu Leu Arg Ser Phe Arg Ser Val Asp 165 170 175

atg tca gga tgc aac tEt gga gat gaa gga tta ttc tht ctt gct gaa Met Ser Gly Cys Asn Phe Gly Asp Glu Gly Leu Phe Phe Leu Ala Glu

-57 180 185 190

agc ctt ggg tat aat cag act gta gag gaa gtc agt tUt tat gca aat Ser Leu Gly Tyr Asn Gln Thr Val Glu Glu Val Ser Phe Ser Ala Asn 195 200 205

gga att aca gct gca gga gUt aaa gcc ttt gat ggt gtt ctt caa tca Gly Ile Thr Ala Ala Gly Val Lys Ala Phe Asp Gly Val Leu Gln Ser 210 215 220

aat att atg tta aaa att ctt aat ctt tct gga aac cct atc ggt gat Asn Ile Met Leu Lys Ile Leu Asn Leu Ser Gly Asn Pro Ile Gly Asp 225 230 235 240

gaa gga gat aag act tta tgc gat aca ctg atg gaa aat tct agc att Glu Gly Ala Lys Thr Leu Cys Ala Thr Leu Met Glu Asn Ser Ser Ile 245 250 255

gag ata ctt cag ctg aac agt act gat ata gga gat gag ggt goa aag Glu Ile Leu Gln Leu Asn Ser Thr Asp Ile Gly Asp Glu Gly Ala Lys 260 265 270

gaa atc gca gaa ttg ttg aag aga aat tcg acc ttg agg att att gag Glu Ile Ala Glu Leu Leu Lys Arg Asn Ser Thr Leu Arg Ile Ile Glu 275 280 285

chg aat aat aac atg att gac tat tat gga ttc aca agt ctt gat gga Leu Asn Asn Asn Met Ile Asp Tyr Ser Gly Phe Thr Ser Leu Ala Gly 290 295 300

gat ctt cUt gag aat aat aca ata cgc aat tta cat ctc aat gga aat Ala Leu Leu Glu Asn Asn Thr Ile Arg Asn Leu His Leu Asn Gly Asn 305 310 315 320

tac ggt ggt gct ttg ggt gac aat gat tta gat aaa ggg ctt gag ggt Tyr Gly Gly Ala Leu Gly Ala Asn Ala Leu Ala Lys Gly Leu Glu Gly 325 330 335

aac aag tat tta cgg gaa cEt cat ttg cat gga aac tat att gga gac Asn Lys Ser Leu Arg Glu Leu His Leu His Gly Asn Ser Ile Gly Asp

-58 340 345 350

gaa ggg act cgt gct ttg aUg gct ggt cta tat tcc cac aaa ggg aaa Glu Gly Thr Arg Ala Leu Met Ala Gly Leu Ser Ser His Lys Gly Lys 355 360 365

gtg gct ttg cta get ctc ggc aac aac tcc att tcc gca aag ggt gcc Val AlaLeu Leu Asp Leu Gly Asn Asn Ser Ile Ser Ala Lys Gly Ala 370 375 380

ttc tat gta gct gaa tac ale aag age agc aag agc ttg gtt tgg ctg Phe Tyr Val Ala Glu Tyr Ile Lys Arg Ser Lys Ser Leu Val Trp Leu 385 390 395 400

aac ctg tac atg eat get ata ggt get gag gga gct gaa aag att goa Asn Leu Tyr Met Asn Asp Ile Gly Asp Glu Gly Ala Glu Lys Ile Ala 405 410 415

get let ctg aag caa aac cgt lea att gca acc att gac ctg ggt gga Asp Ser Leu Lys Gln Asn Arg Ser Ile Ala Thr Ile Asp Leu Gly Gly 420 425 430

eat aac ale cac gcg gag gga gtt eat gct ata gct caa gct ctg aaa Asn Asn Ile His Ala Glu Gly Val Asn Ala Ile Ala Gln Ala Leu Lys 435 440 445

get eat gca att att acg acg tta gag gtt ggt tat eat ccc ata gga Asp Asn Ala Ile Ile Thr Thr Leu Glu Val Gly Tyr Asn Pro Ile Gly 450 455 460

cca gac gga gct aaa gca tta tat gaa att ctc aag tCc cat gga eat Pro Asp Gly Ala Lys Ala Leu Ser Glu Ile Leu Lys Phe His Gly Asn 465 470 475 480

gta aag acg ctc aaa cEt ggt tgg tgt cag ata gct gcc aag ggt gct Val Lys Thr Leu Lys Leu Gly Trp Cys Gln Ile Ala Ala Lys Gly Ala 485 490 495

gaa cat gtt goa gac aLg ttg age tat aac eat ace ale leg gtt ttg Glu His Val Ala Asp Met Leu Arg Tyr Asn Asn Thr Ile Ser Val Leu

-59 500 505 510

gac ttg cgg goa eat gga ctt age get gag gga gct tcc tgc tta gct Asp Leu Arg Ala Asn Gly Leu Arg Asp Glu Gly Ala Ser Cys Leu Ala 515 520 525

cga agc ttg aaa gta gtt eat gaa get ctg ace let gtg get cta gga Arg Ser Leu Lys Val Val Asn Glu Ala Leu Thr Ser Val Asp Leu Gly 530 535 540

ttc eat gaa ata cgg get get gga gca ttc gcc att get caa goa ttg Phe Asn Glu Ile Arg Asp Asp Gly Ala Phe Ala Ile Ala Gln Ala Leu 545 550 555 560

aag gac eat gaa get gtc ace gtt ace leg ata aac cht ggg aac aac Lys Ala Asn Glu Asp Val Thr Val Thr Ser Ile Asn Leu Gly Asn Asn 565 570 575

ttc ale acc aag ttt gga cag agt gcg ctc acg get gct age get cat Phe Ile Thr Lys Phe Gly Gln Ser Ala Leu Thr Asp Ala Arg Asp His 580 585 590

ght ctt gag atg act gaa aag gaa gta gaa att ttc ttc tag Val Leu Glu Met Thr Glu Lys Glu Val Glu Ile Phe Phe 595 600 605

<210> 8

<211> 605

<212> PRT

<213> Arabidopsis thaliana <400> 8

Met Ala Ser Ser Ser Thr Ser Ser Leu Asn Leu His Ser Leu Pro Lys 1 5 10 15

Ala Ser Ser Gly Leu Gly Gln Trp Lys Ser Gly Phe Arg Tyr Glu Leu

-60 20 25 30

Leu Gly Ser Ser Val Ser Arg Asn Arg Leu Phe Val Ser Pro Val Val 35 40 45

Ile His His Arg Ser Pro Arg Leu Pro Ala Ile Lys Ala Ala Tyr Asn 50 55 60

Ser Asp Gly Gly Ser Lys Arg Ser Arg Val Tyr Lys Glu Ser Gln Ala 65 70 75 80

Ala Ser Gly Phe Pro Asn Ala Lys Val Gln Gln Ile Ala Ser Ser Val 85 90 95

Leu Pro Leu Gly Ser Phe Ala Val Val Thr Phe Val Leu Trp Lys Val 100 105 110

Val Gly Lys Phe Met Ser Pro Lys Ser Pro Lys Thr Ser Ala Gly Glu 115 120 125

Asn Asn Ser Ser Thr Gln Gly Val Lys Trp Ser Ile Gly Ala Gly Thr 130 135 140

Asn Leu Leu Gln Gly Phe Ala Ala Lys Val Asp Arg Glu Ala Lys Gln 145 150 155 160

Arg Leu Asn Glu Phe Ala Lys Glu Leu Arg Ser Phe Arg Ser Val Asp 165 170 175

Met Ser Gly Cys Asn Phe Gly Asp Glu Gly Leu Phe Phe Leu Ala Glu 180 185 190

Ser Leu Gly Tyr Asn Gln Thr Val Glu Glu Val Ser Phe Ser Ala Asn 195 200 205

Gly Ile Thr Ala Ala Gly Val Lys Ala Phe Asp Gly Val Leu Gln Ser 210 215 220

-61 Asn Ile Met Leu Lys Ile Leu Asn Leu Ser Gly Asn Pro Ile Gly Asp 225 230 235 240

Glu Gly Ala Lys Thr Leu Cys Ala Thr Leu Met Glu Asn Ser Ser Ile 245 250 255

Glu Ile Leu Gln Leu Asn Ser Thr Asp Ile Gly Asp Glu Gly Ala Lys 260 265 270

Glu Ile Ala Glu Leu Leu Lys Arg Asn Ser Thr Leu Arg Ile Ile Glu 275 280 285

Leu Asn Asn Asn Met Ile Asp Tyr Ser Gly Phe Thr Ser Leu Ala Gly 290 295 300

Ala Leu Leu Glu Asn Asn Thr Ile Arg Asn Leu His Leu Asn Gly Asn 305 310 315 320

Tyr Gly Gly Ala Leu Gly Ala Asn Ala Leu Ala Lys Gly Leu Glu Gly 325 330 335

Asn Lys Ser Leu Arg Glu Leu His Leu His Gly Asn Ser Ile Gly Asp 340 345 350

Glu Gly Thr Arg Ala Leu Met Ala Gly Leu Ser Ser His Lys Gly Lys 355 360 365

Val Ala Leu Leu Asp Leu Gly Asn Asn Ser Ile Ser Ala Lys Gly Ala 370 375 380

Phe Tyr Val Ala Glu Tyr Ile Lys Arg Ser Lys Ser Leu Val Trp Leu 385 390 395 400

Asn Leu Tyr Met Asn Asp Ile Gly Asp Glu Gly Ala Glu Lys Ile Ala 405 410 415

Asp Ser Leu Lys Gln Asn Arg Ser Ile Ala Thr Ile Asp Leu Gly Gly

-62 420 425 430

Asn Asn Ile His Ala Glu Gly Val Asn Ala Ile Ala Gln Ala Leu Lys 435 440 445

Asp Asn Ala Ile Ile Thr Thr Leu Glu Val Gly Tyr Asn Pro Ile Gly 450 455 460

Pro Asp Gly Ala Lys Ala Leu Ser Glu Ile Leu Lys Phe His Gly Asn 465 470 475 480

Val Lys Thr Leu Lys Leu Gly Trp Cys Gln Ile Ala Ala Lys Gly Ala 485 490 495

Glu His Val Ala Asp Met Leu Arg Tyr Asn Asn Thr Ile Ser Val Leu 500 505 510

Asp Leu Arg Ala Asn Gly Leu Arg Asp Glu Gly Ala Ser Cys Leu Ala 515 520 525

Arg Ser Leu Lys Val Val Asn Glu Ala Leu Thr Ser Val Asp Leu Gly 530 535 540

Phe Asn Glu Ile Arg Asp Asp Gly Ala Phe Ala Ile Ala Gln Ala Leu 545 550 555 560

Lys Ala Asn Glu Asp Val Thr Val Thr Ser Ile Asn Leu Gly Asn Asn 565 570 575

Phe Ile Thr Lys Phe Gly Gln Ser Ala Leu Thr Asp Ala Arg Asp His 580 585 590

Val Leu Glu Met Thr Glu Lys Glu Val Glu Ile Phe Phe 595 600 605

<210> 9

-63 <211> 1593

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1593)

<223> <400> 9

aLg agg ace ctc tgg eat cac ttt agt acc att tcc tat ale aaa att Met Arg Thr Leu Trp Asn His Phe Ser Thr Ile Ser Tyr Ile Lys Ile 1 5 10 15

let ccg age atg age age att let gca goa eat ttg ale lea eat cga Ser Pro Arg Met Arg Arg Ile Ser Ala Ala Asn Leu Ile Ser Asn Arg 20 25 30

eat ctt lea acc att let let act gaa get ccc gag ctc age get ttt Asn Leu Ser Thr Ile Ser Ser Thr Glu Asp Pro Glu Leu Arg Asp Phe 35 40 45

gtg gga ttt tta gaa let ctc aaa aac tat gag aaa lea ggt gta cca Val Gly Phe Leu Glu Ser Leu Lys Asn Tyr Glu Lys Ser Gly Val Pro 50 55 60

aaa gga get gga act get tat get get gga tEc get ctg ggt cga aLg Lys Gly Ala Gly Thr Asp Ser Asp Asp Gly Phe Asp Leu Gly Arg Met 65 70 75 80

aaa cgt ctc atg ctt cgc ctc cgt eat cat cat tac aaa tac aag ght Lys Arg Leu Met Leu Arg Leu Arg Asn Pro His Tyr Lys Tyr Lys Val 85 90 95

-64 gtt cat gtt gct gga act aag gga aaa gga tca act tct gct ttt ctc Val His Val Ala Gly Thr Lys Gly Lys Gly Ser Thr Ser Ala Phe Leu 100 105 110

tct aat atc tta cga gat gga gga tat tct gtt ggt tgt tat tct agc Ser Asn Ile Leu Arg Ala Gly Gly Tyr Ser Val Gly Cys Tyr Ser Ser 115 120 125

cca cat att ctg agt atc aaa gaa cgg att tct tgt aat gga gaa cct Pro His Ile Leu Ser Ile Lys Glu Arg Ile Ser Cys Asn Gly Glu Pro 130 135 140

gtc tct gct tcc act ctt aat gat ctt ttc tat tca gtc aaa ccg att Val Ser Ala Ser Thr Leu Asn Asp Leu Phe Tyr Ser Val Lys Pro Ile 145 150 155 160

ctt gaa cag tat att caa gag gaa aat ggt tat ttg agt cat ttt gag Leu Glu Gln Ser Ile Gln Glu Glu Asn Gly Ser Leu Ser His Phe Glu 165 170 175

att ctc act ggg ata gcc ttc tct tta ttt gaa aag gaa aat gtc gac Ile Leu Thr Gly Ile Ala Phe Ser Leu Phe Glu Lys Glu Asn Val Asp 180 185 190

att gag gtt ata gag gat ggg cta gga gga gct cga gac gct aca aat Ile Ala Val Ile Glu Ala Gly Leu Gly Gly Ala Arg Asp Ala Thr Asn 195 200 205

gtc att gaa agt tca aat ctt gat gca tcg gtc ata aca acg ata ggt Val Ile Glu Ser Ser Asn Leu Ala Ala Ser Val Ile Thr Thr Ile Gly 210 215 220

gag gaa cac atg goa gca ctt ggg ggt tcc ttg gaa agt ata goa gag Glu Glu His Met Ala Ala Leu Gly Gly Ser Leu Glu Ser Ile Ala Glu 225 230 235 240

gat aaa tat gga att att aaa cac ggt cgc cca gtg gtt tta ggt gga Ala Lys Ser Gly Ile Ile Lys His Gly Arg Pro Val Val Leu Gly Gly 245 250 255

-65 ccg ttt ctt cct cat atc gag ggc att ctc cgt tct aaa gca gct tca Pro Phe Leu Pro His Ile Glu Gly Ile Leu Arg Ser Lys Ala Ala Ser 260 265 270

gtg tag tca tcg gtt att ttg gca tct aat att gga tat agt tct tca Val Ser Ser Ser Val Ile Leu Ala Ser Asn Ile Gly Ser Ser Ser Ser 275 280 285

atc aaa ggc atc att aac aaa aat ggg atc ggg ctt tgc cag tcc tgt Ile Lys Gly Ile Ile Asn Lys Asn Gly Ile Gly Leu Cys Gln Ser Cys 290 295 300

gac atc gtg ata cag aat gag aaa gat gat caa cca att gtt gag ctt Asp Ile Val Ile Gln Asn Glu Lys Asp Asp Gln Pro Ile Val Glu Leu 305 310 315 320

agt gat gta aac cta cgt atg ctt gga cat cac cag ctc caa aat gct Ser Asp Val Asn Leu Arg Met Leu Gly His His Gln Leu Gln Asn Ala 325 330 335

gtt act gcc aca tgt gtg tct ctt tgt ctt cgc gat caa gga tgt ggg Val Thr Ala Thr Cys Val Ser Leu Cys Leu Arg Asp Gln Gly Cys Gly 340 345 350

aga gtg aca gat gaa gca att agg att ggt tta gag aac act cgt tta Arg Val Thr Asp Glu Ala Ile Arg Ile Gly Leu Glu Asn Thr Arg Leu 355 360 365

ctt ggg aga agt cag ttt ctg aca cca aaa gaa gca gag act tta cta Leu Gly Arg Ser Gln Phe Leu Thr Pro Lys Glu Ala Glu Thr Leu Leu 370 375 380

tta cac gga goa aca gtg ctt cUt gat gga gct cac acc aaa gag tca Leu Pro Gly Ala Thr Val Leu Leu Asp Gly Ala His Thr Lys Glu Ser 385 390 395 400

gcg cga gac ctc aag gag atg ata aag aag gat ttt cca gag aaa aga Ala Arg Ala Leu Lys Glu Met Ile Lys Lys Asp Phe Pro Glu Lys Arg 405 410 415

-66 ttg gta ttt gtg gtt gcc atg gct agt gac aaa gat cat gtg tcc ttt Leu Val Phe Val Val Ala Met Ala Ser Asp Lys Asp His Val Ser Phe 420 425 430

gca aaa gaa ctt ctc tca ggt cta aaa cca gaa gca gtg att cta aca Ala Lys Glu Leu Leu Ser Gly Leu Lys Pro Glu Ala Val Ile Leu Thr 435 440 445

gaa gct gac atc ggt gga ggt aag att aga tca acg gag tat tcg gtg Glu Ala Asp Ile Gly Gly Gly Lys Ile Arg Ser Thr Glu Ser Ser Val 450 455 460

ttg aaa gaa tca tgg ata aaa gat gct gat gaa ttg ggg tca agg tct Leu Lys Glu Ser Trp Ile Lys Ala Ala Asp Glu Leu Gly Ser Arg Ser 465 470 475 480

atg gaa gct tca gaa aac aaa act gtg ttg ggt tcc tta aag ctt gac Met Glu Ala Ser Glu Asn Lys Thr Val Leu Gly Ser Leu Lys Leu Ala 485 490 495

tac aag ata ctc agc gat gac aca aca agt agt gac tca gga atg gtt Tyr Lys Ile Leu Ser Asp Asp Thr Thr Ser Ser Asp Ser Gly Met Val 500 505 510

ata gtc acg ggt tcg ctt cac att gta tct tca gtc tta gct tct ctt Ile Val Thr Gly Ser Leu His Ile Val Ser Ser Val Leu Ala Ser Leu 515 520 525

caa cat taa Gln His <210> 10

<211> 530

<212> PRT

<213> Arabidopsis thaliana

-67 <400> 10

Met Arg Thr Leu Trp Asn His Phe Ser Thr Ile Ser Tyr Ile Lys Ile 1 5 10 15

Ser Pro Arg Met Arg Arg Ile Ser Ala Ala Asn Leu Ile Ser Asn Arg Asn Leu Ser Thr Ile Ser Ser Thr Glu Asp Pro Glu Leu Arg Asp Phe 35 40 45

Val Gly Phe Leu Glu Ser Leu Lys Asn Tyr Glu Lys Ser Gly Val Pro 50 55 60

Lys Gly Ala Gly Thr Asp Ser Asp Asp Gly Phe Asp Leu Gly Arg Met 65 70 75 80

Lys Arg Leu Met Leu Arg Leu Arg Asn Pro His Tyr Lys Tyr Lys Val 85 90 95

Val His Val Ala Gly Thr Lys Gly Lys Gly Ser Thr Ser Ala Phe Leu 100 105 110

Ser Asn Ile Leu Arg Ala Gly Gly Tyr Ser Val Gly Cys Tyr Ser Ser 115 120 125

Pro His Ile Leu Ser Ile Lys Glu Arg Ile Ser Cys Asn Gly Glu Pro 130 135 140

Val Ser Ala Ser Thr Leu Asn Asp Leu Phe Tyr Ser Val Lys Pro Ile Leu Glu Gln Ser Ile Gln Glu Glu Asn Gly Ser Leu Ser His Phe Glu Ile Leu Thr Gly Ile Ala Phe Ser Leu Phe Glu Lys Glu Asn Val Asp 180 185 190

-68 Ile Ala Val Ile Glu Ala Gly Leu Gly Gly Ala Arg Asp Ala Thr Asn 195 200 205

Val Ile Glu Ser Ser Asn Leu Ala Ala Ser Val Ile Thr Thr Ile Gly 210 215 220

Glu Glu His Met Ala Ala Leu Gly Gly Ser Leu Glu Ser Ile Ala Glu 225 230 235 240

Ala Lys Ser Gly Ile Ile Lys His Gly Arg Pro Val Val Leu Gly Gly 245 250 255

Pro Phe Leu Pro His Ile Glu Gly Ile Leu Arg Ser Lys Ala Ala Ser 260 265 270

Val Ser Ser Ser Val Ile Leu Ala Ser Asn Ile Gly Ser Ser Ser Ser 275 280 285

Ile Lys Gly Ile Ile Asn Lys Asn Gly Ile Gly Leu Cys Gln Ser Cys 290 295 300

Asp Ile Val Ile Gln Asn Glu Lys Asp Asp Gln Pro Ile Val Glu Leu 305 310 315 320

Ser Asp Val Asn Leu Arg Met Leu Gly His His Gln Leu Gln Asn Ala 325 330 335

Val Thr Ala Thr Cys Val Ser Leu Cys Leu Arg Asp Gln Gly Cys Gly 340 345 350

Arg Val Thr Asp Glu Ala Ile Arg Ile Gly Leu Glu Asn Thr Arg Leu 355 360 365

Leu Gly Arg Ser Gln Phe Leu Thr Pro Lys Glu Ala Glu Thr Leu Leu 370 375 380

-69 Leu Pro Gly Ala Thr Val Leu Leu Asp Gly Ala His Thr Lys Glu Ser 385 390 395 400

Ala Arg Ala Leu Lys Glu Met Ile Lys Lys Asp Phe Pro Glu Lys Arg 405 410 415

Leu Val Phe Val Val Ala Met Ala Ser Asp Lys Asp His Val Ser Phe 420 425 430

Ala Lys Glu Leu Leu Ser Gly Leu Lys Pro Glu Ala Val Ile Leu Thr 435 440 445

Glu Ala Asp Ile Gly Gly Gly Lys Ile Arg Ser Thr Glu Ser Ser Val 450 455 460

Leu Lys Glu Ser Trp Ile Lys Ala Ala Asp Glu Leu Gly Ser Arg Ser 465 470 475 480

Met Glu Ala Ser Glu Asn Lys Thr Val Leu Gly Ser Leu Lys Leu Ala 485 490 495

Tyr Lys Ile Leu Ser Asp Asp Thr Thr Ser Ser Asp Ser Gly Met Val 500 505 510

Ile Val Thr Gly Ser Leu His Ile Val Ser Ser Val Leu Ala Ser Leu 515 520 525

Gln His <210> 11

<211> 2055

<212> DNA

<213> Arabidopsis thaliana

-70 <220> <221> CDS

<222> (1)..(2055)

<223> <400> 11

aUg goa aag acg agt tgt gaa aka atc ctc tgt ttc ttc ttc ttc att Met Ala Lys Thr Ser Cys Glu Xaa Ile Leu Cys Phe Phe Phe Phe Ile 1 5 10 15

tta agc ttc agg gtc att tct gtt tct gca caa caa act tgt gac aac Leu Ser Phe Arg Val Ile Ser Val Ser Ala Gln Gln Thr Cys Asp Asn 20 25 30

act gat ggt agt ttc aaa cac aat agt act tat gac aac aac cgt cgt Thr Ala Gly Ser Phe Lys Pro Asn Ser Thr Tyr Asp Asn Asn Arg Arg 35 40 45

ctc ctc ctc tct acc ttc gcc tct aac gtc acg gat cag aac ggc tac Leu Leu Leu Ser Thr Phe Ala Ser Asn Val Thr Ala Gln Asn Gly Tyr 50 55 60

ttc aat ggt tcg ttc ggg ctt ggt aca gac aga gtc tac gcc aLg ggg Phe Asn Gly Ser Phe Gly Leu Gly Thr Asp Arg Val Tyr Ala Met Gly 65 70 75 80

atg tgc gat cca ggt gct gaa cct gat gUt tgc tcc aac tgt att aag Met Cys Ala Pro Gly Ala Glu Pro Asp Val Cys Ser Asn Cys Ile Lys 85 90 95

aac aca goa gag ggt tta cta cag atc tgt cta aac cag acg gac ggt Asn Thr Ala Glu Gly Leu Leu Gln Ile Cys Leu Asn Gln Thr Asp Gly 100 105 110

ttc tca tgg tat ggt gaa gaa acc ctt tgc ctt gtt cgt tac tct aac Phe Ser Trp Ser Gly Glu Glu Thr Leu Cys Leu Val Arg Tyr Ser Asn 115 120 125

-71 aaa tcc tCc tcc ggg cta cUt ggc ttg gag ccg tct aat gat ttc ttc Lys Ser Phe Ser Gly Leu Leu Gly Leu Glu Pro Ser Asn Asp Phe Phe 130 135 140

aat gLa aac gaa ata aga aaa gaa gac cag aag gaa ttt gat agt gtg Asn Val Asn Glu Ile Arg Lys Glu Asp Gln Lys Glu Phe Asp Ser Val 145 150 155 160

ttt gat gag tta atg ttt cgt aca atc caa gga gca tct tca tcg gtg Phe Asp Glu Leu Met Phe Arg Thr Ile Gln Gly Ala Ser Ser Ser Val 165 170 175

aga aac aat tct aat tag tta tca ttg tct ggt aaa tat tat gca aag Arg Asn Asn Ser Asn Ser Leu Ser Leu Ser Gly Lys Tyr Tyr Ala Lys 180 185 190

gat gLa gct cct gaa ccg gtt tac ggg aac ata tcg gtg gtg atg caa Asp Val Ala Pro Glu Pro Val Tyr Gly Asn Ile Ser Val Val Met Gln 195 200 205

tgc act cca gat gtt tct tca aag gat tgt aat ctt tgt ctt gag aga Cys Thr Pro Asp Val Ser Ser Lys Asp Cys Asn Leu Cys Leu Glu Arg 210 215 220

agt ctt gat ttc tat aag aaa tgg tac aat ggg aag aga ggc acc att Ser Leu Asp Phe Tyr Lys Lys Trp Tyr Asn Gly Lys Arg Gly Thr Ile 225 230 235 240

ata ttg cgg cca agt tgc ttt ttc cgg tgg gaa ttg tat act ttc tht Ile Leu Arg Pro Ser Cys Phe Phe Arg Trp Glu Leu Tyr Thr Phe Phe 245 250 255

ggt gat ttt gat agt att aat gat aga cac cca cag cct cat cca cgc Gly Ala Phe Asp Ser Ile Asn Ala Arg His Pro Pro Pro Pro Pro Arg 260 265 270

cag ctt tca ccg ccc cat tta aag acg cct tct gLa acc aac caa acc Pro Leu Ser Pro Pro Pro Leu Lys Thr Pro Ser Val Thr Asn Gln Thr 275 280 285

-72 aat att acc aag aag aat ggc aag tcc tUt ttt gga atc tca gga gga Asn Ile Thr Lys Lys Asn Gly Lys Ser Phe Phe Gly Ile Ser Gly Gly 290 295 300

act atc gag gcg ata gtc gtt gta gtt gtt gUt aca ata ata ttg att Thr Ile Ala Ala Ile Val Val Val Val Val Val Thr Ile Ile Leu Ile 305 310 315 320

gUt gta ggc ttg gtt ata tgc aag aga aga aag caa aag caa gaa att Val Val Gly Leu Val Ile Cys Lys Arg Arg Lys Gln Lys Gln Glu Ile 325 330 335

gaa ctt cca acg gaa tct ght cag ttt gat tta aag aca att gaa gca Glu Leu Pro Thr Glu Ser Val Gln Phe Asp Leu Lys Thr Ile Glu Ala 340 345 350

goa acg ggc aac ttt tct gag cat aac aag ctt ggt gca ggt gga tEt Ala Thr Gly Asn Phe Ser Glu His Asn Lys Leu Gly Ala Gly Gly Phe 355 360 365

ggt gaa gtt tac aag ggt atg ctt ttg aat ggg act gaa att gcg gta Gly Glu Val Tyr Lys Gly Met Leu Leu Asn Gly Thr Glu Ile Ala Val 370 375 380

aaa aga ttg tca aaa aca tca gga caa ggt gaa ata gag tUc aag aac Lys Arg Leu Ser Lys Thr Ser Gly Gln Gly Glu Ile Glu Phe Lys Asn 385 390 395 400

gag gtg ght gUt gUt goa aag ctt caa cac ata aat ctt ght aga cUt Glu Val Val Val Val Ala Lys Leu Gln His Ile Asn Leu Val Arg Leu 405 410 415

ctc ggg ttt tcg ctc caa gga gaa gag aag tta ctc gtc tat gaa ttt Leu Gly Phe Ser Leu Gln Gly Glu Glu Lys Leu Leu Val Tyr Glu Phe 420 425 430

gtt cca aac aaa agt ctc gat tat thc ctt ttt gac cat aac aag aga Val Pro Asn Lys Ser Leu Asp Tyr Phe Leu Phe Asp Pro Asn Lys Arg 435 440 445

-73 aat cag ttg gac tgg ace gtg age cgc aac ale ale ggt ggg att act Asn Gln Leu Asp Trp Thr Val Arg Arg Asn Ile Ile Gly Gly Ile Thr 450 455 460

cga gga att cta tat ctt cat caa get lea cgg ctc aaa ale ata cat Arg Gly Ile Leu Tyr Leu His Gln Asp Ser Arg Leu Lys Ile Ile His 465 470 475 480

cgt gac ctc aaa gag agt aac att ctc tta get gcg get atg aac ccg Arg Asp Leu Lys Ala Ser Asn Ile Leu Leu Asp Ala Asp Met Asn Pro 485 490 495

aaa att gct get ttc gga atg gca agg ale tUt gga gtg gac caa act Lys Ile Ala Asp Phe Gly Met Ala Arg Ile Phe Gly Val Asp Gln Thr 500 505 510

gta gac eat acc gca age gta gtt gga acc ttt ggt tac aUg let cct Val Ala Asn Thr Ala Arg Val Val Gly Thr Phe Gly Tyr Met Ser Pro 515 520 525

gag tat gtg ace cat ggc caa ttc lea aLg aaa lea gac gtc tat agt Glu Tyr Val Thr His Gly Gln Phe Ser Met Lys Ser Asp Val Tyr Ser 530 535 540

ttt gga gLa ttg att cht gag ale att agt ggc aaa aag eat agc agc Phe Gly Val Leu Ile Leu Glu Ile Ile Ser Gly Lys Lys Asn Ser Ser 545 550 555 560

ttc tat cag atg get ggc tta ght aac eat tta gEc ace tat gtc tgg Phe Tyr Gln Met Asp Gly Leu Val Asn Asn Leu Val Thr Tyr Val Trp 565 570 575

aaa ctt tgg gag aac aaa ace aLg cat gag ctc ata get cac ttt att Lys Leu Trp Glu Asn Lys Thr Met His Glu Leu Ile Asp Pro Phe Ile 580 585 590

aaa gaa get tgt aaa agc get gaa gtc att age tac gtt cat att ggg Lys Glu Asp Cys Lys Ser Asp Glu Val Ile Arg Tyr Val His Ile Gly 595 600 605

-74 ctg tta tgt gtt caa gaa eat cct goa get cga cca ace atg tat acg Leu Leu Cys Val Gln Glu Asn Pro Ala Asp Arg Pro Thr Met Ser Thr 610 615 620

att cac caa gtg ctc ace acc agc lea att act cta cct gtg cct cag Ile His Gln Val Leu Thr Thr Ser Ser Ile Thr Leu Pro Val Pro Gln 625 630 635 640

cca cct gga ttt thc ttc agg aac gga cca gga leg aac cca lea agc Pro Pro Gly Phe Phe Phe Arg Asn Gly Pro Gly Ser Asn Pro Ser Ser 645 650 655

cag gga atg gtg cct ggt caa leg agc agc aag let tUt act agt let Gln Gly Met Val Pro Gly Gln Ser Ser Ser Lys Ser Phe Thr Ser Ser 660 665 670

gta get gaa gca ace ale acc caa gtt eat cct cgt tga Val Asp Glu Ala Thr Ile Thr Gln Val Asn Pro Arg 675 680

<210> 12

<211> 684

<212> PRT

<213> Arabidopsis thaliana <220> <221> misc_feature <222> (8)..(8)

<223> The 'Xaa' at location 8 stands for Arg, or Ile.

<400> 12

Met Ala Lys Thr Ser Cys Glu Xaa Ile Leu Cys Phe Phe Phe Phe Ile 1 5 10 15

-75 Leu Ser Phe Arg Val Ile Ser Val Ser Ala Gln Gln Thr Cys Asp Asn 20 25 30

Thr Ala Gly Ser Phe Lys Pro Asn Ser Thr Tyr Asp Asn Asn Arg Arg 35 40 45

Leu Leu Leu Ser Thr Phe Ala Ser Asn Val Thr Ala Gln Asn Gly Tyr 50 55 60

Phe Asn Gly Ser Phe Gly Leu Gly Thr Asp Arg Val Tyr Ala Met Gly 65 70 75 80

Met Cys Ala Pro Gly Ala Glu Pro Asp Val Cys Ser Asn Cys Ile Lys 85 90 95

Asn Thr Ala Glu Gly Leu Leu Gln Ile Cys Leu Asn Gln Thr Asp Gly 100 105 110

Phe Ser Trp Ser Gly Glu Glu Thr Leu Cys Leu Val Arg Tyr Ser Asn 115 120 125

Lys Ser Phe Ser Gly Leu Leu Gly Leu Glu Pro Ser Asn Asp Phe Phe 130 135 140

Asn Val Asn Glu Ile Arg Lys Glu Asp Gln Lys Glu Phe Asp Ser Val 145 150 155 160

Phe Asp Glu Leu Met Phe Arg Thr Ile Gln Gly Ala Ser Ser Ser Val 165 170 175

Arg Asn Asn Ser Asn Ser Leu Ser Leu Ser Gly Lys Tyr Tyr Ala Lys 180 185 190

Asp Val Ala Pro Glu Pro Val Tyr Gly Asn Ile Ser Val Val Met Gln 195 200 205

Cys Thr Pro Asp Val Ser Ser Lys Asp Cys Asn Leu Cys Leu Glu Arg

-76 210 215 220

Ser Leu Asp Phe Tyr Lys Lys Trp Tyr Asn Gly Lys Arg Gly Thr Ile Ile Leu Arg Pro Ser Cys Phe Phe Arg Trp Glu Leu Tyr Thr Phe Phe 245 250 255

Gly Ala Phe Asp Ser Ile Asn Ala Arg His Pro Pro Pro Pro Pro Arg Pro Leu Ser Pro Pro Pro Leu Lys Thr Pro Ser Val Thr Asn Gln Thr 275 280 285

Asn Ile Thr Lys Lys Asn Gly Lys Ser Phe Phe Gly Ile Ser Gly Gly Thr Ile Ala Ala Ile Val Val Val Val Val Val Thr Ile Ile Leu Ile 305 310 315 320

Val Val Gly Leu Val Ile Cys Lys Arg Arg Lys Gln Lys Gln Glu Ile Glu Leu Pro Thr Glu Ser Val Gln Phe Asp Leu Lys Thr Ile Glu Ala Ala Thr Gly Asn Phe Ser Glu His Asn Lys Leu Gly Ala Gly y Gly Glu Val Tyr Lys Gly Met Leu Leu Asn Gly Thr Glu Ile Ala Val Lys Arg Leu Ser Lys Thr Ser Gly Gln Gly Glu Ile Glu Phe Lys Asn Glu Val Val Val Val Ala Lys Leu Gln His Ile Asn Leu Val Arg Leu

-77 Leu Gly Phe Ser Leu Gln Gly Glu Glu Lys Leu Leu Val Tyr Glu Phe 420 425 430

Val Pro Asn Lys Ser Leu Asp Tyr Phe Leu Phe Asp Pro Asn Lys Arg 435 440 445

Asn Gln Leu Asp Trp Thr Val Arg Arg Asn Ile Ile Gly Gly Ile Thr 450 455 460

Arg Gly Ile Leu Tyr Leu His Gln Asp Ser Arg Leu Lys Ile Ile His 465 470 475 480

Arg Asp Leu Lys Ala Ser Asn Ile Leu Leu Asp Ala Asp Met Asn Pro 485 490 495

Lys Ile Ala Asp Phe Gly Met Ala Arg Ile Phe Gly Val Asp Gln Thr 500 505 510

Val Ala Asn Thr Ala Arg Val Val Gly Thr Phe Gly Tyr Met Ser Pro 515 520 525

Glu Tyr Val Thr His Gly Gln Phe Ser Met Lys Ser Asp Val Tyr Ser 530 535 540

Phe Gly Val Leu Ile Leu Glu Ile Ile Ser Gly Lys Lys Asn Ser Ser 545 550 555 560

Phe Tyr Gln Met Asp Gly Leu Val Asn Asn Leu Val Thr Tyr Val Trp 565 570 575

Lys Leu Trp Glu Asn Lys Thr Met His Glu Leu Ile Asp Pro Phe Ile 580 585 590

Lys Glu Asp Cys Lys Ser Asp Glu Val Ile Arg Tyr Val His Ile Gly 595 600 605

Leu Leu Cys Val Gln Glu Asn Pro Ala Asp Arg Pro Thr Met Ser Thr

-78 610 615 620

Ile His Gln Val Leu Thr Thr Ser Ser Ile Thr Leu Pro Val Pro Gln 625 630 635 640

Pro Pro Gly Phe Phe Phe Arg Asn Gly Pro Gly Ser Asn Pro Ser Ser 645 650 655

Gln Gly Met Val Pro Gly Gln Ser Ser Ser Lys Ser Phe Thr Ser Ser 660 665 670

Val Asp Glu Ala Thr Ile Thr Gln Val Asn Pro Arg 675 680

<210> 13

*<211> 5178

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(5178)

<223> <400> 13

atg gac tag tat gct gtt eat gcg acg gaa gct act gaa caa eat get Met Asp Ser Ser Ala Val Asn Ala Thr Glu Ala Thr Glu Gln Asn Asp 1 5 10 15

ggc agc age caa get gtt chg gag ttc gac ctt aac aaa act cat cag Gly Ser Arg Gln Asp Val Leu Glu Phe Asp Leu Asn Lys Thr Pro Gln 20 25 30

-79 cag aaa ccc tcc aaa agg aaa agg aag ttc atg ccc aag gtg gtc gtg Gln Lys Pro Ser Lys Arg Lys Arg Lys Phe Met Pro Lys Val Val Val 35 40 45

gaa ggc aaa cat aaa age aag cca cgc aaa cct gca gaa ctt ccc aaa Glu Gly Lys Pro Lys Arg Lys Pro Arg Lys Pro Ala Glu Leu Pro Lys 50 55 60

gtg gtc gtg gaa ggc aaa cct aaa agg aag cca cgc aaa gct goa act Val Val Val Glu Gly Lys Pro Lys Arg Lys Pro Arg Lys Ala Ala Thr 65 70 75 80

cag gaa aaa gtg aaa tat aaa gaa acc ggg agt gac aaa aag aaa eat Gln Glu Lys Val Lys Ser Lys Glu Thr Gly Ser Ala Lys Lys Lys Asn 85 90 95

ttg aaa gaa lea goa act aaa aag cca gcc eat gUt gga get atg agc Leu Lys Glu Ser Ala Thr Lys Lys Pro Ala Asn Val Gly Asp Met Ser 100 105 110

aac aaa agc cat gaa gtc ace ctc aaa agt tgc age aaa get ttg eat Asn Lys Ser Pro Glu Val Thr Leu Lys Ser Cys Arg Lys Ala Leu Asn 115 120 125

ttt gac ttg gag eat cct gga get gag agg caa ggt gac let gag tat Phe Asp Leu Glu Asn Pro Gly Asp Ala Arg Gln Gly Asp Ser Glu Ser 130 135 140

gaa att gtc cag aac agt agt ggc gca aac leg tEt tat gag ale age Glu Ile Val Gln Asn Ser Ser Gly Ala Asn Ser Phe Ser Glu Ile Arg 145 150 155 160

get gac att ggt gga act eat ggt agt tEc ctg get lea gtg lea caa Asp Ala Ile Gly Gly Thr Asn Gly Ser Phe Leu Asp Ser Val Ser Gln 165 170 175

ata gac aag acc eat gga ttg ggg gct aUg aac cag cca ctt gaa gtg Ile Asp Lys Thr Asn Gly Leu Gly Ala Met Asn Gln Pro Leu Glu Val 180 185 190

-80 tca atg gga aac cag cca gat aaa cta tct aca gga gcg aaa ctg gcc Ser Met Gly Asn Gln Pro Asp Lys Leu Ser Thr Gly Ala Lys Leu Ala 195 200 205

aga gac caa caa cct gat tta ttg act aga aac cag caa tgc cag ttc Arg Asp Gln Gln Pro Asp Leu Leu Thr Arg Asn Gln Gln Cys Gln Phe 210 215 220

cca gUg goa acc cag aac acc cag ttc cca atg gaa aac caa caa gct Pro Val Ala Thr Gln Asn Thr Gln Phe Pro Met Glu Asn Gln Gln Ala 225 230 235 240

tgg ctt cag atg aaa aac caa ctt att ggc ttt cca ttt ggt aac cag Trp Leu Gln Met Lys Asn Gln Leu Ile Gly Phe Pro Phe Gly Asn Gln 245 250 255

caa cat cgc atg acc ata aga aac cag cag cct tgc ttg gcc aUg ggt Gln Pro Arg Met Thr Ile Arg Asn Gln Gln Pro Cys Leu Ala Met Gly 260 265 270

aat caa caa cct aLg tat ctg ata gga act cca cgg cct gca tta gLa Asn Gln Gln Pro Met Tyr Leu Ile Gly Thr Pro Arg Pro Ala Leu Val 275 280 285

agt gga aac cag caa cta gga ggt cac caa gga aac aag cgg cct ata Ser Gly Asn Gln Gln Leu Gly Gly Pro Gln Gly Asn Lys Arg Pro Ile 290 295 300

ttt ttg aat cac cag act tgt tta cct gat gga aat cag cta tat gga Phe Leu Asn His Gln Thr Cys Leu Pro Ala Gly Asn Gln Leu Tyr Gly 305 310 315 320

tca cct aca gac atg cat caa ctt gtt atg tca acc gga ggg caa caa Ser Pro Thr Asp Met His Gln Leu Val Met Ser Thr Gly Gly Gln Gln 325 330 335

cat gga cta ctg ata aaa aac cag caa cct gga tca tta ata aga ggc His Gly Leu Leu Ile Lys Asn Gln Gln Pro Gly Ser Leu Ile Arg Gly 340 345 350

-81 cag cag cct tgc gLa cat ttg att gac cag caa cct gca act cca aaa Gln Gln Pro Cys Val Pro Leu Ile Asp Gln Gln Pro Ala Thr Pro Lys 355 360 365

ggt ttt act cac ttg eat cag atg gUa gct acc agc atg lea leg cct Gly Phe Thr His Leu Asn Gln Met Val Ala Thr Ser Met Ser Ser Pro 370 375 380

ggg ctt cga cct cat let cag lea caa gtt cat ace ace tat cta cat Gly Leu Arg Pro His Ser Gln Ser Gln Val Pro Thr Thr Tyr Leu His 385 390 395 - 400

gtg gaa tat gtt tcc agg att ttg eat ggg act ace ggt ace tgc cag Val Glu Ser Val Ser Arg Ile Leu Asn Gly Thr Thr Gly Thr Cys Gln 405 410 415

age agc agg gct cct gca tac get tat tta cag caa get ale cat caa Arg Ser Arg Ala Pro Ala Tyr Asp Ser Leu Gln Gln Asp Ile His Gln 420 425 430

gga eat aag tac ata ctt let cat gag ata tcc eat ggt eat ggg tgc Gly Asn Lys Tyr Ile Leu Ser His Glu Ile Ser Asn Gly Asn Gly Cys 435 440 445

aag aaa gcg tta cat caa aac let let ctg cca act cca att atg gct Lys Lys Ala Leu Pro Gln Asn Ser Ser Leu Pro Thr Pro Ile Met Ala 450 455 460

aaa ctt gag gaa gac agg ggc leg aag age cag tat cat cgt goa aUg Lys Leu Glu Glu Ala Arg Gly Ser Lys Arg Gln Tyr His Arg Ala Met 465 470 475 480

gga cag acg gaa aag cat get cta aac tta gct caa cag att get caa Gly Gln Thr Glu Lys His Asp Leu Asn Leu Ala Gln Gln Ile Ala Gln 485 490 495

lea caa get gtg gag age cat aac agc agc acg tgt gtg gaa tat tta Ser Gln Asp Val Glu Arg His Asn Ser Ser Thr Cys Val Glu Tyr Leu 500 505 510

-82 gat gct gca aag aaa acg aaa ale cag aaa gta gtc caa gaa eat ttg Asp Ala Ala Lys Lys Thr Lys Ile Gln Lys Val Val Gln Glu Asn Leu 515 520 525

cat ggc atg cca cat gag gtt ata gaa ale gag get get cca act get His Gly Met Pro Pro Glu Val Ile Glu Ile Glu Asp Asp Pro Thr Asp 530 535 540

ggg gca age aaa ggt aaa eat act gcc agc ale agt aaa ggt gca let Gly Ala Arg Lys Gly Lys Asn Thr Ala Ser Ile Ser Lys Gly Ala Ser 545 550 555 560

aaa gga aac leg tat cca gtt aaa aag ace gca gaa aag gag aaa tgt Lys GlyAsn Ser Ser Pro Val Lys Lys Thr Ala Glu Lys Glu Lys Cys 565 570 575

att gtc cca aaa acg cct gca aaa aag ggt cga goa ggt age aaa aaa Ile Val Pro Lys Thr Pro Ala Lys Lys Gly Arg Ala Gly Arg Lys Lys 580 585 590

lea gta cat ccg cct gct cat gcc lea gag ale cag ctt tgg caa cct Ser Val Pro Pro Pro Ala His Ala Ser Glu Ile Gln Leu Trp Gln Pro 595 600 605

act cct cca aag ace cat tta lea age agc aag cat aaa gga aaa ggg Thr Pro Pro Lys Thr Pro Leu Ser Arg Ser Lys Pro Lys Gly Lys Gly 610 615 620

age aag tcc ata caa get lea gga aaa goa age ggt cca lea gga gaa Arg Lys Ser Ile Gln Asp Ser Gly Lys Ala Arg Gly Pro Ser Gly Glu 625 630 635 640

cEt ctg tgt cag get tat att gcg gaa ata att tac agg atg caa eat Leu Leu Cys Gln Asp Ser Ile Ala Glu Ile Ile Tyr Arg Met Gln Asn 645 650 655

ctg tat cta gga gac aaa gaa age gaa caa gag caa eat goa atg gtc Leu Tyr Leu Gly Asp Lys Glu Arg Glu Gln Glu Gln Asn Ala Met Val 660 665 670

-83 ttg tac aaa gga gat ggt gca ctt gtt ccc tat gag agc aag aag cga Leu Tyr Lys Gly Asp Gly Ala Leu Val Pro Tyr Glu Ser Lys Lys Arg 675 680 685

aaa cca aga ccc aaa gtt gac att gac gat gaa aca act cgc ata tgg Lys Pro Arg Pro Lys Val Asp Ile Asp Asp Glu Thr Thr Arg Ile Trp 690 695 700

aac tta ctg atg ggg aaa gga gat gaa aaa gaa ggg gat gaa gag aag Asn Leu Leu Met Gly Lys Gly Asp Glu Lys Glu Gly Asp Glu Glu Lys 705 710 715 720

gat aaa aag aaa gag aag tgg tgg gaa gaa gaa aga aga gtc ttc cga Asp Lys Lys Lys Glu Lys Trp Trp Glu Glu Glu Arg Arg Val Phe Arg 725 730 735

gga agg gat gat tcc ttc atc gct cgc atg cac ctg gLa caa gga gat Gly Arg Ala Asp Ser Phe Ile Ala Arg Met His Leu Val Gln Gly Asp 740 745 750

aga cgt ttt tcg cca tgg aag gga tcg gtg gtt gat tcg gtc att gga Arg Arg Phe Ser Pro Trp Lys Gly Ser Val Val Asp Ser Val Ile Gly 755 760 765

gUt tCc cUt aca cag aat gtc tcg gat cac ctt tca agc tat gcg tCc Val Phe Leu Thr Gln Asn Val Ser Asp His Leu Ser Ser Ser Ala Phe 770 775 780

atg tat cta gat gct cga ttc cct cca aaa tta agc agc agc cga gaa Met Ser Leu Ala Ala Arg Phe Pro Pro Lys Leu Ser Ser Ser Arg Glu 785 790 795 800

gat gaa agg aat ght aga agc gta gtt gtt gaa gat cca gaa gga tgc Asp Glu Arg Asn Val Arg Ser Val Val Val Glu Asp Pro Glu Gly Cys 805 810 815

att chg aac tta aat gaa att cct tag tgg cag gaa aag gtt caa cat Ile Leu Asn Leu Asn Glu Ile Pro Ser Trp Gln Glu Lys Val Gln His 820 825 830

-84 cca tct gac atg gaa gtt tct ggg gtt gat agt gga tca aaa gag cag Pro Ser Asp Met Glu Val Ser Gly Val Asp Ser Gly Ser Lys Glu Gln 835 840 845

cta agg gac tgt tca aac tct gga att gaa aga ttt aat ttc tta gag Leu Arg Asp Cys Ser Asn Ser Gly Ile Glu Arg Phe Asn Phe Leu Glu 850 855 860

aag agt att caa aat tta gaa gag gaa gta tta tca tca caa gat tct Lys Ser Ile Gln Asn Leu Glu Glu Glu Val Leu Ser Ser Gln Asp Ser 865 870 875 880

ttt gat cag gcg ata ttt cag tcg tgt ggg aga gtt gga tcc tgt tca Phe Asp Pro Ala Ile Phe Gln Ser Cys Gly Arg Val Gly Ser Cys Ser 885 890 895

tgt tcc aaa tca gac gca gag ttt cct aca acc agg tgt gaa aca aaa Cys Ser Lys Ser Asp Ala Glu Phe Pro Thr Thr Arg Cys Glu Thr Lys 900 905 910

act gtc agt gga aca tca caa tca gtg caa act ggg agc cca aac ttg Thr Val Ser Gly Thr Ser Gln Ser Val Gln Thr Gly Ser Pro Asn Leu 915 920 925

tct gat gaa att tgt cEt caa ggg aat gag aga ccg cat cta tat gaa Ser Asp Glu Ile Cys Leu Gln Gly Asn Glu Arg Pro His Leu Tyr Glu 930 935 940

gga tat ggt gat gtt cag aaa caa gaa act aca aat gtc gat cag aag Gly Ser Gly Asp Val Gln Lys Gln Glu Thr Thr Asn Val Ala Gln Lys 945 950 955 960

aaa cat gat cUt gaa aaa aca atg aat tgg aaa gac tat gtc tgt ttt Lys Pro Asp Leu Glu Lys Thr Met Asn Trp Lys Asp Ser Val Cys Phe 965 970 975

ggt cag cca aga aat gat act aat tgg caa aca act cat tcc agc agc Gly Gln Pro Arg Asn Asp Thr Asn Trp Gln Thr Thr Pro Ser Ser Ser 980 985 990

-85 tat gag cag tgt gag act cga cag cca cat gLa cta gac ata gag get Tyr Glu Gln Cys Ala Thr Arg Gln Pro His Val Leu Asp Ile Glu Asp 995 1000 1005

ttt gga atg caa ggt gaa ggc ctt ggt tat let tgg atg tcc ale Phe Gly Met Gln Gly Glu Gly Leu Gly Tyr Ser Trp Met Ser Ile 1010 1015 1020

lea cca age gtt gac age gta aag aac aaa eat gta cca cgc agg Ser Pro Arg Val Asp Arg Val Lys Asn Lys Asn Val Pro Arg Arg 1025 1030 1035

ttt ttc age caa ggt gga agt gtt cca age gaa ttc ace ggt cag Phe Phe Arg Gln Gly Gly Ser Val Pro Arg Glu Phe Thr Gly Gln 1040 1045 1050

ale ata cca lea acg cct cat gaa tta cca gga atg gga ttg tcc Ile Ile Pro Ser Thr Pro His Glu Leu Pro Gly Met Gly Leu Ser 1055 1060 1065

ggt tcc lea agc gcc gtc caa gaa cac cag gac get acc caa cat Gly Ser Ser Ser Ala Val Gln Glu His Gln Asp Asp Thr Gln His 1070 1075 1080

eat caa caa get gag aLg eat aaa gca tcc cat tta caa aaa ace Asn Gln Gln Asp Glu Met Asn Lys Ala Ser His Leu Gln Lys Thr 1085 1090 1095

ttt ttg get ctg ctc aac tcc let gaa gaa tgc ctt ace age cag Phe Leu Asp Leu Leu Asn Ser Ser Glu Glu Cys Leu Thr Arg Gln 1100 1105 1110

tcc agt acc aaa cag aac ale acg get ggc tgt cta cag age get Ser Ser Thr Lys Gln Asn Ile Thr Asp Gly Cys Leu Pro Arg Asp 1115 1120 1125

age act gct gaa gac gtg gtt get cag ctc agt aac eat lea agc Arg Thr Ala Glu Asp Val Val Asp Pro Leu Ser Asn Asn Ser Ser 1130 1135 1140

-86 tta cag aac ata ttg gtc gaa tca aat tcc agc aat aaa gag cag Leu Gln Asn Ile Leu Val Glu Ser Asn Ser Ser Asn Lys Glu Gln 1145 1150 1155

acg gca gtt gaa tac aag gag aca aat gcc act att tta cga gag Thr Ala Val Glu Tyr Lys Glu Thr Asn Ala Thr Ile Leu Arg Glu 1160 1165 1170

atg aaa ggg acg ctt gct gat ggg aaa aag cct aca agc cag tgg Met Lys Gly Thr Leu Ala Asp Gly Lys Lys Pro Thr Ser Gln Trp 1175 1180 1185

gat agt ctc aga aaa gat gtg gag ggg aat gaa ggg aga cag gaa Asp Ser Leu Arg Lys Asp Val Glu Gly Asn Glu Gly Arg Gln Glu 1190 1195 1200

cga aac aaa aac aat atg gat tcc ata gac tat gaa gca ata aga Arg Asn Lys Asn Asn Met Asp Ser Ile Asp Tyr Glu Ala Ile Arg 1205 1210 1215

cgt gct agt atc agc gag att tat gag gct atc aag gaa aga ggg Arg Ala Ser Ile Ser Glu Ile Ser Glu Ala Ile Lys Glu Arg Gly 1220 1225 1230

aUg aat aac aLg ttg gcc gta cga att aag gat ttc cta gaa cgg Met Asn Asn Met Leu Ala Val Arg Ile Lys Asp Phe Leu Glu Arg 1235 1240 1245

ata gtt aaa gat cat ggt ggt atc gac ctt gaa tgg ttg aga gaa Ile Val Lys Asp His Gly Gly Ile Asp Leu Glu Trp Leu Arg Glu 1250 1255 1260

tct cct cct gat aaa gac aag gac tat ctc ttg agc ata aga ggt Ser Pro Pro Asp Lys Ala Lys Asp Tyr Leu Leu Ser Ile Arg Gly 1265 1270 1275

ctg ggt ttg aaa agt gtt gaa tgc gtg cga ctc tta aca ctc cac Leu Gly Leu Lys Ser Val Glu Cys Val Arg Leu Leu Thr Leu His 1280 1285 1290

-87 aat ctt gct ttc cat gtt gac acg eat gtt gga agg ata goa gtt Asn Leu Ala Phe Pro Val Asp Thr Asn Val Gly Arg Ile Ala Val 1295 1300 1305

agg atg gga tgg gtg cat cta caa ccc cta cat gaa lea ctt cag Arg Met Gly Trp Val Pro Leu Gln Pro Leu Pro Glu Ser Leu Gln 1310 1315 1320

tta cac ctc ctg gag cta tac cca gtg ctc gag tcc ale caa aaa Leu His Leu Leu Glu Leu Tyr Pro Val Leu Glu Ser Ile Gln Lys 1325 1330 1335

ttt ctt tgg cca age ctt tgc aaa ctc get caa cga ace ctg tat Phe Leu Trp Pro Arg Leu Cys Lys Leu Asp Gln Arg Thr Leu Tyr 1340 1345 1350

gaa tta cac tac caa ctg att acg ttt gga aag gta ttt tgc ace Glu Leu His Tyr Gln Leu Ile Thr Phe Gly Lys Val Phe Cys Thr 1355 1360 1365

aag agt age cca eat tgt eat gca tgt cca atg age gga gag tgc Lys Ser Arg Pro Asn Cys Asn Ala Cys Pro Met Arg Gly Glu Cys 1370 1375 1380

age cac ttt gcc agt gct tat gct agt gca age ctt gct tta ccg Arg His Phe Ala Ser Ala Tyr Ala Ser Ala Arg Leu Ala Leu Pro 1385 1390 1395

goa cca gag gag agg agc tta ace agt gca act att ccg gtc cct Ala Pro Glu Glu Arg Ser Leu Thr Ser Ala Thr Ile Pro Val Pro 1400 1405 1410

ccc gag tcc ttt cat cat gta gcc ale cag aLg ata gaa cta cct Pro Glu Ser Phe Pro Pro Val Ala Ile Pro Met Ile Glu Leu Pro 1415 1420 1425

cEt ccg ttg gag aaa tcc cta gca agt gga goa cca tag eat age Leu Pro Leu Glu Lys Ser Leu Ala Ser Gly Ala Pro Ser Asn Arg 1430 1435 1440

-88 gaa aac tgt gaa cca ata att gaa gag cag gcc leg ccc ggg caa Glu Asn Cys Glu Pro Ile Ile Glu Glu Pro Ala Ser Pro Gly Gln 1445 1450 1455

gag tgc act gaa ata acc gag agt get att gaa get gct tac tac Glu Cys Thr Glu Ile Thr Glu Ser Asp Ile Glu Asp Ala Tyr Tyr 1460 1465 1470

eat gag gac cct gac gag ale cca ace ata aaa ctc aac att gaa Asn Glu Asp Pro Asp Glu Ile Pro Thr Ile Lys Leu Asn Ile Glu 1475 1480 1485

cag ttt gga atg act cta cgg gaa cac atg gaa age aac atg gag Gln Phe Gly Met Thr Leu Arg Glu His Met Glu Arg Asn Met Glu 1490 1495 1500

ctc caa gaa ggt gac aUg tcc aag gct ttg gtt gct ttg cat cca Leu Gln Glu Gly Asp Met Ser Lys Ala Leu Val Ala Leu His Pro 1505 1510 1515

ace act act let att cca act cac aaa cta aag aac att agc cgt Thr Thr Thr Ser Ile Pro Thr Pro Lys Leu Lys Asn Ile Ser Arg 1520 1525 1530

ctc agg ace gag cac caa gtg tac gag ctc cca get lea cat cgt Leu Arg Thr Glu His Gln Val Tyr Glu Leu Pro Asp Ser His Arg 1535 1540 1545

ctc ctt get ggt aLg get aaa age gaa cca get get cca agt cat Leu Leu Asp Gly Met Asp Lys Arg Glu Pro Asp Asp Pro Ser Pro 1550 1555 1560

tat ctc tta gct ata tgg ace cca ggt gaa ace gcg eat leg gca Tyr Leu Leu Ala Ile Trp Thr Pro Gly Glu Thr Ala Asn Ser Ala 1565 1570 1575

caa ccg cat gaa cag aag tgt gga ggg aaa gag let ggc aaa aLg Gln Pro Pro Glu Gln Lys Cys Gly Gly Lys Ala Ser Gly Lys Met 1580 1585 1590

-89 tgc ttt gac gag act tgt tct gag tgt aac agt chg agg gaa gca Cys Phe Asp Glu Thr Cys Ser Glu Cys Asn Ser Leu Arg Glu Ala 1595 1600 1605

aac tca cag aca gtt cga gga act ctt ctg ata cct tgt cgg act Asn Ser Gln Thr Val Arg Gly Thr Leu Leu Ile Pro Cys Arg Thr 1610 1615 1620

gcc atg aga gga agt tUt ccg ctc aac ggg aca tat ttc caa gtc Ala Met Arg Gly Ser Phe Pro Leu Asn Gly Thr Tyr Phe Gln Val 1625 1630 1635

aac gag tta tUt goa gac cac gag tcc agt ctc aaa ccc atc gat Asn Glu Leu Phe Ala Asp His Glu Ser Ser Leu Lys Pro Ile Asp 1640 1645 1650

gtt cct aga gat tgg ata tgg gat ctc cca aga agg act gtt tac Val Pro Arg Asp Trp Ile Trp Asp Leu Pro Arg Arg Thr Val Tyr 1655 1660 1665

ttc gga aca tca gta aca tca ata ttc aga ggt cUt tca acg gag Phe Gly Thr Ser Val Thr Ser Ile Phe Arg Gly Leu Ser Thr Glu 1670 1675 1680

cag ata cag ttc tgc tht tgg aaa gga ttc gta tgt gtc cgt gga Gln Ile Gln Phe Cys Phe Trp Lys Gly Phe Val Cys Val Arg Gly 1685 1690 1695

ttc gaa cag aag aca aga gca ccg cgt cca tta atg goa agg ttg Phe Glu Gln Lys Thr Arg Ala Pro Arg Pro Leu Met Ala Arg Leu 1700 1705 1710

cat ttt cct gag agc aaa ttg aag aac aac aaa acc taa His Phe Pro Ala Ser Lys Leu Lys Asn Asn Lys Thr 1715 1720 1725

<210i 14 <211> 1725

- 9o -

<212> PRT

<213> Arabidopsis thaliana <400> 14

Met Asp Ser Ser Ala Val Asn Ala Thr Glu Ala Thr Glu Gln Asn Asp 1 5 10 15

Gly Ser Arg Gln Asp Val Leu Glu Phe Asp Leu Asn Lys Thr Pro Gln 20 25 30

Gln Lys Pro Ser Lys Arg Lys Arg Lys Phe Met Pro Lys Val Val Val 35 40 45

Glu Gly Lys Pro Lys Arg Lys Pro Arg Lys Pro Ala Glu Leu Pro Lys 50 55 60

Val Val Val Glu Gly Lys Pro Lys Arg Lys Pro Arg Lys Ala Ala Thr 65 70 75 80

Gln Glu Lys Val Lys Ser Lys Glu Thr Gly Ser Ala Lys Lys Lys Asn 85 90 95

Leu Lys Glu Ser Ala Thr Lys Lys Pro Ala Asn Val Gly Asp Met Ser 100 105 110

Asn Lys Ser Pro Glu Val Thr Leu Lys Ser Cys Arg Lys Ala Leu Asn 115 120 125

Phe Asp Leu Glu Asn Pro Gly Asp Ala Arg Gln Gly Asp Ser Glu Ser 130 135 140

Glu Ile Val Gln Asn Ser Ser Gly Ala Asn Ser Phe Ser Glu Ile Arg 145 150 155 160

Asp Ala Ile Gly Gly Thr Asn Gly Ser Phe Leu Asp Ser Val Ser Gln 165 170 175

-91 Ile Asp Lys Thr Asn Gly Leu Gly Ala Met Asn Gln Pro Leu Glu Val 180 185 190

Ser Met Gly Asn Gln Pro Asp Lys Leu Ser Thr Gly Ala Lys Leu Ala 195 200 205

Arg Asp Gln Gln Pro Asp Leu Leu Thr Arg Asn Gln Gln Cys Gln Phe 210 215 220

Pro Val Ala Thr Gln Asn Thr Gln Phe Pro Met Glu Asn Gln Gln Ala 225 230 235 240

Trp Leu Gln Met Lys Asn Gln Leu Ile Gly Phe Pro Phe Gly Asn Gln 245 250 255

Gln Pro Arg Met Thr Ile Arg Asn Gln Gln Pro Cys Leu Ala Met Gly 260 265 270

Asn Gln Gln Pro Met Tyr Leu Ile Gly Thr Pro Arg Pro Ala Leu Val 275 280 285

Ser Gly Asn Gln Gln Leu Gly Gly Pro Gln Gly Asn Lys Arg Pro Ile 290 295 300

Phe Leu Asn His Gln Thr Cys Leu Pro Ala Gly Asn Gln Leu Tyr Gly 305 310 315 320

Ser Pro Thr Asp Met His Gln Leu Val Met Ser Thr Gly Gly Gln Gln 325 330 335

His Gly Leu Leu Ile Lys Asn Gln Gln Pro Gly Ser Leu Ile Arg Gly 340 345 350

Gln Gln Pro Cys Val Pro Leu Ile Asp Gln Gln Pro Ala Thr Pro Lys 355 360 365

-92 Gly Phe Thr His Leu Asn Gln Met Val Ala Thr Ser Met Ser Ser Pro 370 375 380

Gly Leu Arg Pro His Ser Gln Ser Gln Val Pro Thr Thr Tyr Leu His 385 390 395 400

Val Glu Ser Val Ser Arg Ile Leu Asn Gly Thr Thr Gly Thr Cys Gln 405 410 415

Arg Ser Arg Ala Pro Ala Tyr Asp Ser Leu Gln Gln Asp Ile His Gln 420 425 430

Gly Asn Lys Tyr Ile Leu Ser His Glu Ile Ser Asn Gly Asn Gly Cys 435 440 445

Lys Lys Ala Leu Pro Gln Asn Ser Ser Leu Pro Thr Pro Ile Met Ala 450 455 460

Lys Leu Glu Glu Ala Arg Gly Ser Lys Arg Gln Tyr His Arg Ala Met 465 470 475 480

Gly Gln Thr Glu Lys His Asp Leu Asn Leu Ala Gln Gln Ile Ala Gln 485 490 495

Ser Gln Asp Val Glu Arg His Asn Ser Ser Thr Cys Val Glu Tyr Leu 500 505 510

Asp Ala Ala Lys Lys Thr Lys Ile Gln Lys Val Val Gln Glu Asn Leu 515 520 525

His Gly Met Pro Pro Glu Val Ile Glu Ile Glu Asp Asp Pro Thr Asp 530 535 540

Gly Ala Arg Lys Gly Lys Asn Thr Ala Ser Ile Ser Lys Gly Ala Ser 545 550 555 560

Lys Gly Asn Ser Ser Pro Val Lys Lys Thr Ala Glu Lys Glu Lys Cys 565 570 575

-93 Ile Val Pro Lys Thr Pro Ala Lys Lys Gly Arg Ala Gly Arg Lys Lys Ser Val Pro Pro Pro Ala His Ala Ser Glu Ile Gln Leu Trp Gln Pro 595 600 605

Thr Pro Pro Lys Thr Pro Leu Ser Arg Ser Lys Pro Lys Gly Lys Gly Arg Lys Ser Ile Gln Asp Ser Gly Lys Ala Arg Gly Pro Ser Gly Glu Leu Leu Cys Gln Asp Ser Ile Ala Glu Ile Ile Tyr Arg Met Gln Asn 645 650 655

Leu Tyr Leu Gly Asp Lys Glu Arg Glu Gln Glu Gln Asn Ala Met Val 660 665 670

Leu Tyr Lys Gly Asp Gly Ala Leu Val Pro Tyr Glu Ser Lys Lys Arg Lys Pro Arg Pro Lys Val Asp Ile Asp Asp Glu Thr Thr Arg Ile Trp Asn Leu Leu Met Gly Lys Gly Asp Glu Lys Glu Gly Asp Glu Glu Lys Asp Lys Lys Lys Glu Lys Trp Trp Glu Glu Glu Arg Arg Val Phe Arg Gly Arg Ala Asp Ser Phe Ile Ala Arg Met His Leu Val Gln Gly Asp 740 745 750

Arg Arg Phe Ser Pro Trp Lys Gly Ser Val Val Asp Ser Val Ile Gly 755 760 765

-94 Val Phe Leu Thr Gln Asn Val Ser Asp His Leu Ser Ser Ser Ala Phe Met Ser Leu Ala Ala Arg Phe Pro Pro Lys Leu Ser Ser Ser Arg Glu Asp Glu Arg Asn Val Arg Ser Val Val Val Glu Asp Pro Glu Gly Cys Ile Leu Asn Leu Asn Glu Ile Pro Ser Trp Gln Glu Lys Val Gln His 820 825 830

Pro Ser Asp Met Glu Val Ser Gly Val Asp Ser Gly Ser Lys Glu Gln 835 840 845

Leu Arg Asp Cys Ser Asn Ser Gly Ile Glu Arg Phe Asn Phe Leu Glu 855 860

Lys Ser Ile Gln Asn Leu Glu Glu Glu Val Leu Ser Ser Gln Asp Ser Phe Asp Pro Ala Ile Phe Gln Ser Cys Gly Arg Val Gly Ser Cys Ser Cys Ser Lys Ser Asp Ala Glu Phe Pro Thr Thr Arg Cys Glu Thr Lys Thr Val Ser Gly Thr Ser Gln Ser Val Gln Thr Gly Ser Pro Asn Leu Ser Asp Glu Ile Cys Leu Gln Gly Asn Glu Arg Pro His Leu Tyr Glu Gly Ser Gly Asp Val Gln Lys Gln Glu Thr Thr Asn Val Ala Gln Lys Lys Pro Asp Leu Glu Lys Thr Met Asn Trp Lys Asp Ser Val Cys Phe 965 970 975

-95 Gly Gln Pro Arg Asn Asp Thr Asn Trp Gln Thr Thr Pro Ser Ser Ser 980 985 990

Tyr Glu Gln Cys Ala Thr Arg Gln Pro His Val Leu Asp Ile Glu Asp 995 1000 1005

Phe Gly Met Gln Gly Glu Gly Leu Gly Tyr Ser Trp Met Ser Ile 1010 1015 1020

Ser Pro Arg Val Asp Arg Val Lys Asn Lys Asn Val Pro Arg Arg 1025 1030 1035

Phe Phe Arg Gln Gly Gly Ser Val Pro Arg Glu Phe Thr Gly Gln 1040 1045 1050

Ile Ile Pro Ser Thr Pro His Glu Leu Pro Gly Met Gly Leu Ser 1055 1060 1065

Gly Ser Ser Ser Ala Val Gln Glu His Gln Asp Asp Thr Gln His 1070 1075 1080

Asn Gln Gln Asp Glu Met Asn Lys Ala Ser His Leu Gln Lys Thr 1085 1090 1095

Phe Leu Asp Leu Leu Asn Ser Ser Glu Glu Cys Leu Thr Arg Gln 1100 1105 1110

Ser Ser Thr Lys Gln Asn Ile Thr Asp Gly Cys Leu Pro Arg Asp 1115 1120 1125

Arg Thr Ala Glu Asp Val Val Asp Pro Leu Ser Asn Asn Ser Ser 1130 1135 1140

Leu Gln Asn Ile Leu Val Glu Ser Asn Ser Ser Asn Lys Glu Gln 1145 1150 1155

-96 Thr Ala Val Glu Tyr Lys Glu Thr Asn Ala Thr Ile Leu Arg Glu 1160 1165 1170

Met Lys Gly Thr Leu Ala Asp Gly Lys Lys Pro Thr Ser Gln Trp 1175 1180 1185

Asp Ser Leu Arg Lys Asp Val Glu Gly Asn Glu Gly Arg Gln Glu 1190 1195 1200

Arg Asn Lys Asn Asn Met Asp Ser Ile Asp Tyr Glu Ala Ile Arg 1205 1210 1215

Arg Ala Ser Ile Ser Glu Ile Ser Glu Ala Ile Lys Glu Arg Gly 1220 1225 1230

Met Asn Asn Met Leu Ala Val Arg Ile Lys Asp Phe Leu Glu Arg 1235 1240 1245

Ile Val Lys Asp His Gly Gly Ile Asp Leu Glu Trp Leu Arg Glu 1250 1255 1260

Ser Pro Pro Asp Lys Ala Lys Asp Tyr Leu Leu Ser Ile Arg Gly 1265 1270 1275

Leu Gly Leu Lys Ser Val Glu Cys Val Arg Leu Leu Thr Leu His 1280 1285 1290

Asn Leu Ala Phe Pro Val Asp Thr Asn Val Gly Arg Ile Ala Val 1295 1300 1305

Arg Met Gly Trp Val Pro Leu Gln Pro Leu Pro Glu Ser Leu Gln 1310 1315 1320

Leu His Leu Leu Glu Leu Tyr Pro Val Leu Glu Ser Ile Gln Lys 1325 1330 1335

Phe Leu Trp Pro Arg Leu Cys Lys Leu Asp Gln Arg Thr Leu Tyr 1340 1345 1350

-97 Glu Leu His Tyr Gln Leu Ile Thr Phe Gly Lys Val Phe Cys Thr 1355 1360 1365

Lys Ser Arg Pro Asn Cys Asn Ala Cys Pro Met Arg Gly Glu Cys 1370 1375 1380

Arg His Phe Ala Ser Ala Tyr Ala Ser Ala Arg Leu Ala Leu Pro 1385 1390 1395

Ala Pro Glu Glu Arg Ser Leu Thr Ser Ala Thr Ile Pro Val Pro 1400 1405 1410

Pro Glu Ser Phe Pro Pro Val Ala Ile Pro Met Ile Glu Leu Pro 1415 1420 1425

Leu Pro Leu Glu Lys Ser Leu Ala Ser Gly Ala Pro Ser Asn Arg 1430 1435 1440

Glu Asn Cys Glu Pro Ile Ile Glu Glu Pro Ala Ser Pro Gly Gln 1445 1450 1455

Glu Cys Thr Glu Ile Thr Glu Ser Asp Ile Glu Asp Ala Tyr Tyr 1460 1465 1470

Asn Glu Asp Pro Asp Glu Ile Pro Thr Ile Lys Leu Asn Ile Glu 1475 1480 1485

Gln Phe Gly Met Thr Leu Arg Glu His Met Glu Arg Asn Met Glu 1490 1495 1500

Leu Gln Glu Gly Asp Met Ser Lys Ala Leu Val Ala Leu His Pro 1505 1510 1515

Thr Thr Thr Ser Ile Pro Thr Pro Lys Leu Lys Asn Ile Ser Arg 1520 1525 1530

-98 Leu Arg Thr Glu His Gln Val Tyr Glu Leu Pro Asp Ser His Arg 1535 1540 1545

Leu Leu Asp Gly Met Asp Lys Arg Glu Pro Asp Asp Pro Ser Pro 1550 1555 1560

Tyr Leu Leu Ala Ile Trp Thr Pro Gly Glu Thr Ala Asn Ser Ala 1565 1570 1575

Gln Pro Pro Glu Gln Lys Cys Gly Gly Lys Ala Ser Gly Lys Met 1580 1585 1590

Cys Phe Asp Glu Thr Cys Ser Glu Cys Asn Ser Leu Arg Glu Ala 1595 1600 1605

Asn Ser Gln Thr Val Arg Gly Thr Leu Leu Ile Pro Cys Arg Thr 1610 1615 1620

Ala Met Arg Gly Ser Phe Pro Leu Asn Gly Thr Tyr Phe Gln Val 1625 1630 1635

Asn Glu Leu Phe Ala Asp His Glu Ser Ser Leu Lys Pro Ile Asp 1640 1645 1650

Val Pro Arg Asp Trp Ile Trp Asp Leu Pro Arg Arg Thr Val Tyr 1655 1660 1665

Phe Gly Thr Ser Val Thr Ser Ile Phe Arg Gly Leu Ser Thr Glu 1670 1675 1680

Gln Ile Gln Phe Cys Phe Trp Lys Gly Phe Val Cys Val Arg Gly 1685 1690 1695

Phe Glu Gln Lys Thr Arg Ala Pro Arg Pro Leu Met Ala Arg Leu 1700 1705 1710

His Phe Pro Ala Ser Lys Leu Lys Asn Asn Lys Thr 1715 1720 1725

- 99 -

<210> 15

<211> 2547

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> ()..(2547)

<223> <400> 15

atg get ttg gct cca ctt eat ttt acg gaa atg cca ctg age agc let Met Ala Leu Ala Pro Leu Asn Phe Thr Glu Met Pro Leu Arg Ser Ser 1 5 10 15

ctt cct ctg acc let agc let cgc tat tgt tcc let cat tag ctt cac Leu Pro Leu Thr Ser Ser Ser Arg Tyr Cys Ser Ser Pro Ser Leu His 20 25 30

goa ttg ctc thc tat leg ttg ggt gtg aaa cac leg cgt caa caa att Ala Leu Leu Phe Tyr Ser Leu Gly Val Lys Pro Ser Arg Gln Gln Ile 35 40 45

gtt cgg cca ttc tat leg ctg cgt ace agc gag cgt agc aac aac agg Val Arg Pro Phe Ser Ser Leu Arg Thr Ser Glu Arg Ser Asn Asn Arg 50 55 60

agc eat aac eat cgt cga tta get caa cgt eat cat aaa cat act cat Ser Asn Asn Asn Arg Arg Leu Asp Gln Arg Asn His Lys Pro Thr Pro 65 70 75 80

cat tgg ata get aag tgg cat ccg lea tcc tcc gga get ggc ggt get

-100 Pro Trp Ile Asp Lys Trp Pro Pro Ser Ser Ser Gly Ala Gly Gly Asp 85 90 95

cat gcc ggg aag aaa ggt ggt gaa aac aac ggc gga get age att cgg His Ala Gly Lys Lys Gly Gly Glu Asn Asn Gly Gly Asp Arg Ile Arg 100 105 110

let gag gag gag gaa gcg gaa gcg aaa ctt cgg tat ttg gag aag get Ser Ala Glu Glu Glu Ala Glu Ala Lys Leu Arg Tyr Leu Glu Lys Asp 115 120 125

aaa gga caa aac gag att gag agg att gEt ctt cgg cta cgg eat tta Lys Gly Gln Asn Ala Ile Glu Arg Ile Val Leu Arg Leu Arg Asn Leu 130 135 140

gga tta ggt tag get get gag gac get gtg gaa get gac gag gga ggt Gly Leu Gly Ser Asp Asp Glu Asp Asp Val Glu Asp Asp Glu Gly Gly 145 150 155 160

gga att aac ggc gga get gtg aag cag gtg act gga gaa gag age ttg Gly Ile Asn Gly Gly Asp Val Lys Pro Val Thr Gly Glu Glu Arg Leu 165 170 175

ggg get ttg ttg aag age gag tgg gtg age cct get atg atg ctt gct Gly Asp Leu Leu Lys Arg Glu Trp Val Arg Pro Asp Met Met Leu Ala 180 185 190

gag gga gaa gag agt gag gaa gag get gag gta tta ttg cca tgg gag Glu Gly Glu Glu Ser Glu Glu Glu Asp Glu Val Leu Leu Pro Trp Glu 195 200 205

aaa eat gag gaa gag cag gcg gcg gag age gta gta gga gaa gga gga Lys Asn Glu Glu Glu Gln Ala Ala Glu Arg Val Val Gly Glu Gly Gly 210 215 220

gtg gag gtg atg cag aag agg age gct age gct cca lea chg gcg gag Val Ala Val Met Gln Lys Arg Arg Ala Arg Ala Pro Ser Leu Ala Glu 225 230 235 240

ctc acc gtt gag get let gag tta cgg cgg tta agg agg get gga atg

-101 Leu Thr Val Glu Asp Ser Glu Leu Arg Arg Leu Arg Arg Asp Gly Met 245 250 255

tat ctg agg gtt agg ale eat ata cca aaa gct ggg cta acg cag gca Tyr Leu Arg Val Arg Ile Asn Ile Pro Lys Ala Gly Leu Thr Gln Ala 260 265 270

gtg aLg gag aag att tat get act tgg agg aaa gaa gag ctt gtg agg Val Met Glu Lys Ile Tyr Asp Thr Trp Arg Lys Glu Glu Leu Val Arg 275 280 285

cta aag ttc cac gaa gtg cUt get cgt gac atg aag acg gac cat gag Leu Lys Phe His Glu Val Leu Ala Arg Asp Met Lys Thr Ala His Glu 290 295 300

att gtt gag cgt cga act ggt gga atg gtg ata tgg agg gcc gga agt Ile Val Glu Arg Arg Thr Gly Gly Met Val Ile Trp Arg Ala Gly Ser 305 310 315 320

gUa atg gtg gtt tat cgt gga cht gac tat aaa gga cct cct gtg ale Val Met Val Val Tyr Arg Gly Leu Asp Tyr Lys Gly Pro Pro Val Ile 325 330 335

let eat caa atg gac ggt cct aaa gag act ctt tUt gtc cca get gta Ser Asn Gln Met Ala Gly Pro Lys Glu Thr Leu Phe Val Pro Asp Val 340 345 350

* let let get ggc get gaa goa ace eat gcc aaa get aac caa agt goa Ser Ser Ala Gly Asp Glu Ala Thr Asn Ala Lys Asp Asn Gln Ser Ala 355 360 365

cct ttg gta ale aaa get ccg ale ale aag aac cat att cgc aaa gag Pro Leu Val Ile Lys Asp Pro Ile Ile Lys Asn Pro Ile Arg Lys Glu 370 375 380

eat atg ace gaa gaa gaa gtt gaa tUt aac agt cta tta gac agc tta Asn Met Thr Glu Glu Glu Val Glu Phe Asn Ser Leu Leu Asp Ser Leu 385 390 395 400

ggt cca cgt ttt caa gag tgg tgg ggt act ggg gta cta cct gtg gac

-102 Gly Pro Arg Phe Gln Glu Trp Trp Gly Thr Gly Val Leu Pro Val Asp 405 410 415

gct gac tta cta cat cct aca att cct ggt tat aaa aca cct ttc agg Ala Asp Leu Leu Pro Pro Thr Ile Pro Gly Tyr Lys Thr Pro Phe Arg 420 425 430

ctt ctt cat act ggg atg aga tca aat ttg acc aat gac gaa atg aca Leu Leu Pro Thr Gly Met Arg Ser Asn Leu Thr Asn Ala Glu Met Thr 435 440 445

aat ctc agg aag att ggt aaa act ctc cca tgc cat ttt gct ctt ggt Asn Leu Arg Lys Ile Gly Lys Thr Leu Pro Cys His Phe Ala Leu Gly 450 455 460

agg aac aga aat cac caa gga ttg gca gct gca ata ctc cag atc tgg Arg Asn Arg Asn His Gln Gly Leu Ala Ala Ala Ile Leu Gln Ile Trp 465 470 475 480

gag aaa agt cta att gca aag atc gct gtg aag cga ggt atc cag aat Glu Lys Ser Leu Ile Ala Lys Ile Ala Val Lys Arg Gly Ile Gln Asn 485 490 495

aca aat aac aaa cta atg gcg gat gaa gtg aag aca ttg aca ggg ggt Thr Asn Asn Lys Leu Met Ala Asp Glu Val Lys Thr Leu Thr Gly Gly 500 505 510

gtc ttg ctg ctc aga aat aag tat tac att gta ata tat cgt ggg aag Val Leu Leu Leu Arg Asn Lys Tyr Tyr Ile Val Ile Tyr Arg Gly Lys 515 520 525

gac ttc ctt cat tca agt gtg goa gat act tta goa gaa aga caa gaa Asp Phe Leu Pro Ser Ser Val Ala Ala Thr Leu Ala Glu Arg Gln Glu 530 535 540

tta acg aaa gag att caa gat gtc gaa gag agg gta aga aat cgt gag Leu Thr Lys Glu Ile Gln Asp Val Glu Glu Arg Val Arg Asn Arg Glu 545 550 555 560

att gag gat gtt cag cct gtt ggt gac aaa gta cca gca gaa gct ggc

-103 Ile Glu Ala Val Gln Pro Val Gly Asp Lys Val Pro Ala Glu Ala Gly 565 570 575

act ctg gcc gag tht tat gag gct caa gac cga tgg ggg aag gaa ata Thr Leu Ala Glu Phe Tyr Glu Ala Gln Ala Arg Trp Gly Lys Glu Ile 580 585 590

act cca gac cat cgt gaa aag atg att gaa gaa gct lea agg gtt gca Thr Pro Asp His Arg Glu Lys Met Ile Glu Glu Ala Ser Arg Val Ala 595 600 605

eat gct age ght gtt aaa cga ata caa cac aaa cta aac ctt gac caa Asn Ala Arg Val Val Lys Arg Ile Gln His Lys Leu Asn Leu Ala Gln 610 615 620

leg aag ttt caa age goa gag aaa ctg ttg tcc aaa ata gaa gcc let Ser Lys Phe Gln Arg Ala Glu Lys Leu Leu Ser Lys Ile Glu Ala Ser 625 630 635 640

aLg att cca eat gga cct get tat get caa gag gtc ale tcc gag gaa Met Ile Pro Asn Gly Pro Asp Tyr Asp Gln Glu Val Ile Ser Glu Glu 645 650 655

gaa age gct aLg ttc cgg aaa gtg gga ctg aaa atg aag gca tac tta Glu Arg Ala Met Phe Arg Lys Val Gly Leu Lys Met Lys Ala Tyr Leu 660 665 670

cac ata ggt ale cgt ggt gta ttt get gga gtc att gag aac atg cat Pro Ile Gly Ile Arg Gly Val Phe Asp Gly Val Ile Glu Asn Met His 675 680 685

ctg cat tgg aaa cac age gaa ttg gtg aag ctt ata lea aaa cag aag Leu His Trp Lys His Arg Glu Leu Val Lys Leu Ile Ser Lys Gln Lys 690 695 700

aac caa goa ttt gUt gag gag ace gac cgg tta cta gaa tac gag agt Asn Gln Ala Phe Val Glu Glu Thr Ala Arg Leu Leu Glu Tyr Glu Ser 705 710 715 720

ggt gga gUt ctt gtg gca ata gaa aag ght cat aaa gga ttt gcg ctt

-104 Gly Gly Val Leu Val Ala Ile Glu Lys Val Pro Lys Gly Phe Ala Leu 725 730 735

att tat tac cgt ggg aag eat tac agg age cac att agc ttg age cca Ile Tyr Tyr Arg Gly Lys Asn Tyr Arg Arg Pro Ile Ser Leu Arg Pro 740 745 750

agg eat cUt ctg ace aaa goa aaa gca ttg aaa cgt tcc att goa atg Arg Asn Leu Leu Thr Lys Ala Lys Ala Leu Lys Arg Ser Ile Ala Met 755 760 765

caa cgc cac gag goa ctt agt cag cat att tat gaa ctg gag age ace Gln Arg His Glu Ala Leu Ser Gln His Ile Ser Glu Leu Glu Arg Thr 770 775 780

ata gag caa atg caa agc caa ctc act tag aaa aac ccg lea tac agt Ile Glu Gln Met Gln Ser Gln Leu Thr Ser Lys Asn Pro Ser Tyr Ser 785 790 795 800

gaa lea gaa tgg gag aac get gag get get get get get gaa gaa gaa Glu Ser Glu Trp Glu Asn Asp Glu Asp Asp Asp Asp Asp Glu Glu Glu 805 810 815

gag aaa get get gtg gag get eat gag agt get tgg get gaa act get Glu Lys Asp Asp Val Glu Asp Asn Glu Ser Asp Trp Asp Glu Thr Asp 820 825 830

ggc gaa let gca att let agt ale gaa gaa gct get aLg lea tag cgc Gly Glu Ser Ala Ile Ser Ser Ile Glu Glu Ala Asp Met Ser Ser Arg 835 840 845

tea <210> 16

<211> 848

<212> PRT

<213> Arabidopsis thaliana

-105 <400> 16

Met Ala Leu Ala Pro Leu Asn Phe Thr Glu Met Pro Leu Arg Ser Ser 1 5 10 15

Leu Pro Leu Thr Ser Ser Ser Arg Tyr Cys Ser Ser Pro Ser Leu His 20 25 30

Ala Leu Leu Phe Tyr Ser Leu Gly Val Lys Pro Ser Arg Gln Gln Ile 35 40 45

Val Arg Pro Phe Ser Ser Leu Arg Thr Ser Glu Arg Ser Asn Asn Arg 50 55 60

Ser Asn Asn Asn Arg Arg Leu Asp Gln Arg Asn His Lys Pro Thr Pro 65 70 75 80

Pro Trp Ile Asp Lys Trp Pro Pro Ser Ser Ser Gly Ala Gly Gly Asp 85 90 95

His Ala Gly Lys Lys Gly Gly Glu Asn Asn Gly Gly Asp Arg Ile Arg 100 105 110

Ser Ala Glu Glu Glu Ala Glu Ala Lys Leu Arg Tyr Leu Glu Lys Asp 115 120 125 Lys Gly Gln Asn Ala Ile Glu Arg Ile Val Leu Arg Leu Arg Asn Leu 130 135

140

Gly Leu Gly Ser Asp Asp Glu Asp Asp Val Glu Asp Asp Glu Gly Gly 145 150 155 160

Gly Ile Asn Gly Gly Asp Val Lys Pro Val Thr Gly Glu Glu Arg Leu 165 170 175

Gly Asp Leu Leu Lys Arg Glu Trp Val Arg Pro Asp Met Met Leu Ala 180 185 190

-106 Glu Gly Glu Glu Ser Glu Glu Glu Asp Glu Val Leu Leu Pro Trp Glu 195 200 205

Lys Asn Glu Glu Glu Gln Ala Ala Glu Arg Val Val Gly Glu Gly Gly Val Ala Val Met Gln Lys Arg Arg Ala Arg Ala Pro Ser Leu Ala Glu 225 230 235 240

Leu Thr Val Glu Asp Ser Glu Leu Arg Arg Leu Arg Arg Asp Gly Met Tyr Leu Arg Val Arg Ile Asn Ile Pro Lys Ala Gly Leu Thr Gln Ala 260 265 270

Val Met Glu Lys Ile Tyr Asp Thr Trp Arg Lys Glu Glu Leu Val Arg 275 280 285

Leu Lys Phe His Glu Val Leu Ala Arg Asp Met Lys Thr Ala His Glu 290 295 300

Ile Val Glu Arg Arg Thr Gly Gly Met Val Ile Trp Arg Ala Gly Ser 305 310 315 320

Val Met Val Val Tyr Arg Gly Leu Asp Tyr Lys Gly Pro Pro Val Ile 325 330 335

Ser Asn Gln Met Ala Gly Pro Lys Glu Thr Leu Phe Val Pro Asp Val 340 345 350

Ser Ser Ala Gly Asp Glu Ala Thr Asn Ala Lys Asp Asn Gln Ser Ala 355 360 365

Pro Leu Val Ile Lys Asp Pro Ile Ile Lys Asn Pro Ile Arg Lys Glu 370 375 380

-107 Asn Met Thr Glu Glu Glu Val Glu Phe Asn Ser Leu Leu Asp Ser Leu 385 390 395 400

Gly Pro Arg Phe Gln Glu Trp Trp Gly Thr Gly Val Leu Pro Val Asp 405 410 415

Ala Asp Leu Leu Pro Pro Thr Ile Pro Gly Tyr Lys Thr Pro Phe Arg 420 425 430

Leu Leu Pro Thr Gly Met Arg Ser Asn Leu Thr Asn Ala Glu Met Thr 435 440 445

Asn Leu Arg Lys Ile Gly Lys Thr Leu Pro Cys His Phe Ala Leu Gly 450 455 460

Arg Asn Arg Asn His Gln Gly Leu Ala Ala Ala Ile Leu Gln Ile Trp 465 470 475 480

Glu Lys Ser Leu Ile Ala Lys Ile Ala Val Lys Arg Gly Ile Gln Asn 485 490 495

Thr Asn Asn Lys Leu Met Ala Asp Glu Val Lys Thr Leu Thr Gly Gly 500 505 510

Val Leu Leu Leu Arg Asn Lys Tyr Tyr Ile Val Ile Tyr Arg Gly Lys 515 520 525

Asp Phe Leu Pro Ser Ser Val Ala Ala Thr Leu Ala Glu Arg Gln Glu 530 535 540

Leu Thr Lys Glu Ile Gln Asp Val Glu Glu Arg Val Arg Asn Arg Glu 545 550 555 560

Ile Glu Ala Val Gln Pro Val Gly Asp Lys Val Pro Ala Glu Ala Gly 565 570 575

Thr Leu Ala Glu Phe Tyr Glu Ala Gln Ala Arg Trp Gly Lys Glu Ile 580 585 590

-108 Thr Pro Asp His Arg Glu Lys Met Ile Glu Glu Ala Ser Arg Val Ala 595 600 605

Asn Ala Arg Val Val Lys Arg Ile Gln His Lys Leu Asn Leu Ala Gln 610 615 620

Ser Lys Phe Gln Arg Ala Glu Lys Leu Leu Ser Lys Ile Glu Ala Ser 625 630 635 640

Met Ile Pro Asn Gly Pro Asp Tyr Asp Gln Glu Val Ile Ser Glu Glu 645 650 655

Glu Arg Ala Met Phe Arg Lys Val Gly Leu Lys Met Lys Ala Tyr Leu 660 665 670

Pro Ile Gly Ile Arg Gly Val Phe Asp Gly Val Ile Glu Asn Met His 675 680 685

Leu His Trp Lys His Arg Glu Leu Val Lys Leu Ile Ser Lys Gln Lys 690 695 700

Asn Gln Ala Phe Val Glu Glu Thr Ala Arg Leu Leu Glu Tyr Glu Ser 705 710 715 720

Gly Gly Val Leu Val Ala Ile Glu Lys Val Pro Lys Gly Phe Ala Leu 725 730 735

Ile Tyr Tyr Arg Gly Lys Asn Tyr Arg Arg Pro Ile Ser Leu Arg Pro 740 745 750

Arg Asn Leu Leu Thr Lys Ala Lys Ala Leu Lys Arg Ser Ile Ala Met 755 760 765

Gln Arg His Glu Ala Leu Ser Gln His Ile Ser Glu Leu Glu Arg Thr 770 775 780

-109 Ile Glu Gln Met Gln Ser Gln Leu Thr Ser Lys Asn Pro Ser Tyr Ser 785 790 795 800

Glu Ser Glu Trp Glu Asn Asp Glu Asp Asp Asp Asp Asp Glu Glu Glu 805 810 815

Glu Lys Asp Asp Val Glu Asp Asn Glu Ser Asp Trp Asp Glu Thr Asp 820 825 830

Gly Glu Ser Ala Ile Ser Ser Ile Glu Glu Ala Asp Met Ser Ser Arg 835 840 845

<210> 17

<211> 390

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(390)

<223> <400> 17

atg ctt cat cta tag ctg cUt aaa act get caa ggg cat cat atg ctc Met Leu Pro Leu Ser Leu Leu Lys Thr Ala Gln Gly His Pro Met Leu 1 5 10 15

gtg gag ctt aag eat gga gag ace tac eat ggg cat ttg gtg eat tgt Val Glu Leu Lys Asn Gly Glu Thr Tyr Asn Gly His Leu Val Asn Cys 20 25 30

get act tgg atg aac ale cat chg cgt gaa gEc ata tgt ace lea aag Asp Thr Trp Met Asn Ile His Leu Arg Glu Val Ile Cys Thr Ser Lys

-110 35 40 45

gac gga get age tht tgg agg atg cag gaa tgt tat ale cgt ggt aac Asp Gly Asp Arg Phe Trp Arg Met Pro Glu Cys Tyr Ile Arg Gly Asn 50 55 60

ace ale aag tac ctt cga gtt ccg get gag gUg att get aaa gta cag Thr Ile Lys Tyr Leu Arg Val Pro Asp Glu Val Ile Asp Lys Val Gln 65 70 75 80

gag gag aag ace cgc ace get age aaa cca cca ggt gtt gga cgt gga Glu Glu Lys Thr Arg Thr Asp Arg Lys Pro Pro Gly Val Gly Arg Gly 85 90 95

age gga cgt ggt gtg get get gga gga gcc age ggc age ggc age gga Arg Gly Arg Gly Val Asp Asp Gly Gly Ala Arg Gly Arg Gly Arg Gly 100 105 110

act lea aUg ggg aag atg ggt ggc aac age gga gca ggt cgc ggc cgt Thr Ser Met Gly Lys Met Gly Gly Asn Arg Gly Ala Gly Arg Gly Arg 115 120 125

ggt tga Gly <210> 18

<211> 129

<212> PRT

<213> Arabidopsis thaliana <400> 18

Met Leu Pro Leu Ser Leu Leu Lys Thr Ala Gln Gly His Pro Met Leu 1 5 10 15

Val Glu Leu Lys Asn Gly Glu Thr Tyr Asn Gly His Leu Val Asn Cys

20 25 30

Asp Thr Trp Met Asn Ile His Leu Arg Glu Val Ile Cys Thr Ser Lys 35 40 45

Asp Gly Asp Arg Phe Trp Arg Met Pro Glu Cys Tyr Ile Arg Gly Asn 50 55 60

Thr Ile Lys Tyr Leu Arg Val Pro Asp Glu Val Ile Asp Lys Val Gln 65 70 75 80

Glu Glu Lys Thr Arg Thr Asp Arg Lys Pro Pro Gly Val Gly Arg Gly 85 90 95

Arg Gly Arg Gly Val Asp Asp Gly Gly Ala Arg Gly Arg Gly Arg Gly 100 105 110

Thr Ser Met Gly Lys Met Gly Gly Asn Arg Gly Ala Gly Arg Gly Arg 115 120 125

Gly <210> 19

c211> 1698 <212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1698)

<223>

-112 <400> 19

atg gct leg acc ccg aag ctt acc agt ace att lea lea let let cca Met Ala Ser Thr Pro Lys Leu Thr Ser Thr Ile Ser Ser Ser Ser Pro 1 5 10 15

tat ctt caa ttc ctc tgc aaa aaa ctc cca ale goa att cat cta cca Ser Leu Gln Phe Leu Cys Lys Lys Leu Pro Ile Ala Ile His Leu Pro 20 25 30

lea let tat tcc let agc ttt ctc leg ctt cct aaa acc cta acc let Ser Ser Ser Ser Ser Ser Phe Leu Ser Leu Pro Lys Thr Leu Thr Ser 35 40 45

ctc tat tat ctc cgt cac cgt ale gac cta ctc lea aac cac cgc tat Leu Tyr Ser Leu Arg Pro Arg Ile Ala Leu Leu Ser Asn His Arg Tyr 50 55 60

tac cac let cgc cgg ttt tat gUt tgt gcc agt acc get eat gga gct Tyr His Ser Arg Arg Phe Ser Val Cys Ala Ser Thr Asp Asn Gly Ala 65 70 75 80

gaa lea gac cgc cac tac get ttt get ctc ttc act ale ggt gac gga Glu Ser Asp Arg His Tyr Asp Phe Asp Leu Phe Thr Ile Gly Ala Gly 85 90 95

agc ggc ggc gtc cgc gcc tat cgc tUc gac act agc thc ggt gca tcc Ser Gly Gly Val Arg Ala Ser Arg Phe Ala Thr Ser Phe Gly Ala Ser 100 105 110

gac gcc gtt tgc gag ctt cct ttt tcc act ale let tcc get act gct Ala Ala Val Cys Glu Leu Pro Phe Ser Thr Ile Ser Ser Asp Thr Ala 115 120 125

gga ggc gtt gga gga acg tgt gta ttg age gga tgt gta cca aag aag Gly Gly Val Gly Gly Thr Cys Val Leu Arg Gly Cys Val Pro Lys Lys 130 135 140

tta cht gtg tat gca tcc aaa tac agt cat gag ttt gaa gac agt cat

-113 Leu Leu Val Tyr Ala Ser Lys Tyr Ser His Glu Phe Glu Asp Ser His 145 150 155 160

gga ttt ggt tgg aag tat gag act gag cct let cat get tgg act act Gly Phe Gly Trp Lys Tyr Glu Thr Glu Pro Ser His Asp Trp Thr Thr 165 170 175

ttg att gct aac aag eat gct gag tta cag cgg ttg act ggt att tat Leu Ile Ala Asn Lys Asn Ala Glu Leu Gln Arg Leu Thr Gly Ile Tyr 180 185 190

aag eat ata ctg agc aaa gct eat gtc aag ttg att gaa ggt cgt gga Lys Asn Ile Leu Ser Lys Ala Asn Val Lys Leu Ile Glu Gly Arg Gly 195 200 205

aag gtt ata gac cca cac act gtt get gLa get ggg aaa ale tat act Lys Val Ile Asp Pro His Thr Val Asp Val Asp Gly Lys Ile Tyr Thr 210 215 220

acg agg eat att ctg att gca gtt ggt gga cgt cct ttc att cat gac Thr Arg Asn Ile Leu Ile Ala Val Gly Gly Arg Pro Phe Ile Pro Asp 225 230 235 240

att cca gga aaa gag ttt get att get let get gcc gcg cUt get ttg Ile Pro Gly Lys Glu Phe Ala Ile Asp Ser Asp Ala Ala Leu Asp Leu 245 250 255

cct tcc aag cat aag aaa att gca ata gtt ggt ggt ggc tac ata gcc Pro Ser Lys Pro Lys Lys Ile Ala Ile Val Gly Gly Gly Tyr Ile Ala 260 265 270

chg gag tUt gag ggg ale ttc eat ggt cUt aac tgt gaa gtt cat gta Leu Glu Phe Ala Gly Ile Phe Asn Gly Leu Asn Cys Glu Val His Val 275 280 285

ttt ata agg caa aag aag gUg ctg agg gga tUt get gaa get gtc agg Phe Ile Arg Gln Lys Lys Val Leu Arg Gly Phe Asp Glu Asp Val Arg 290 295 300

get ttc gtt gga gag cag atg tat tta age ggt att gag tUt cac act

-114 Asp Phe Val Gly Glu Gln Met Ser Leu Arg Gly Ile Glu Phe His Thr 305 310 315 320

gaa gaa tcc cct gaa gcc ale ale aaa gct gga get ggc leg ttc let Glu Glu Ser Pro Glu Ala Ile Ile Lys Ala Gly Asp Gly Ser Phe Ser 325 330 335

ctg aag acc agc aag gga act gtt gag gga ttt leg cat ght atg tUt Leu Lys Thr Ser Lys Gly Thr Val Glu Gly Phe Ser His Val Met Phe 340 345 350

gca act ggt cgc aag ccc aac ace aag aac tta ggg ttg gag eat gUt Ala Thr Gly Arg Lys Pro Asn Thr Lys Asn Leu Gly Leu Glu Asn Val 355 360 365

ggc ght aaa atg gag aaa eat gga gca ata gag gtt gac gaa tat lea Gly Val Lys Met Ala Lys Asn Gly Ala Ile Glu Val Asp Glu Tyr Ser 370 375 380

cag ace tat gtt cca tcc ale tgg gct gtt ggg get gUt act gac cga Gln Thr Ser Val Pro Ser Ile Trp Ala Val Gly Asp Val Thr Asp Arg 385 390 395 400

ale eat ttg act cca gtt gct ttg aLg gag gga ggt gca ttg get aaa Ile Asn Leu Thr Pro Val Ala Leu Met Glu Gly Gly Ala Leu Ala Lys 405 410 415

act ttg ttt caa eat gag cca ace aag cat get tat age get gtt ccc Thr Leu Phe Gln Asn Glu Pro Thr Lys Pro Asp Tyr Arg Ala Val Pro 420 425 430

tgc gcc gtt ttc tcc cag cca cat att gga ace gtt ggt cta act gaa Cys Ala Val Phe Ser Gln Pro Pro Ile Gly Thr Val Gly Leu Thr Glu 435 440 445

gag cag gcc ata gaa caa tat ggt get gtg get gUt tac ace tag aac Glu Gln Ala Ile Glu Gln Tyr Gly Asp Val Asp Val Tyr Thr Ser Asn 450 455 460

ttt agg cca tta aag get acc ctt lea gga ctt cca gac cga gLa tht

-115 Phe Arg Pro Leu Lys Ala Thr Leu Ser Gly Leu Pro Asp Arg Val Phe 465 470 475 480

aUg aaa ctc att gEc tgt gca aac acc eat aaa gtt ctc ggt gtt cac Met Lys Leu Ile Val Cys Ala Asn Thr Asn Lys Val Leu Gly Val His 485 490 495

atg tgt gga gaa get lea cca gaa ale ale cag gga ttt ggg gUt gca Met Cys Gly Glu Asp Ser Pro Glu Ile Ile Gln Gly Phe Gly Val Ala 500 505 510

gUt aaa gct ggt tta act aag gcc gac tUt get gct ace gtg ggt gtt Val Lys Ala Gly Leu Thr Lys Ala Asp Phe Asp Ala Thr Val Gly Val 515 520 525

cac ccc ace gca gct gag gag tUt gtc act atg agg get cca acc agg His Pro Thr Ala Ala Glu Glu Phe Val Thr Met Arg Ala Pro Thr Arg 530 535 540

aaa ttc cgc aaa gac tcc let gag gga aag gca agt cat gaa gct aaa Lys Phe Arg Lys Asp Ser Ser Glu Gly Lys Ala Ser Pro Glu Ala Lys 545 550 555 560

ace get gct ggg gtg tag Thr Ala Ala Gly Val <210> 20

<211> 565

<212> PRT

<213> Arabidopsis thaliana <400> 20

Met Ala Ser Thr Pro Lys Leu Thr Ser Thr Ile Ser Ser Ser Ser Pro 1 5 10 15

-116 Ser Leu Gln Phe Leu Cys Lys Lys Leu Pro Ile Ala Ile His Leu Pro 20 25 30

Ser Ser Ser Ser Ser Ser Phe Leu Ser Leu Pro Lys Thr Leu Thr Ser 35 40 45

Leu Tyr Ser Leu Arg Pro Arg Ile Ala Leu Leu Ser Asn His Arg Tyr 50 55 60

Tyr His Ser Arg Arg Phe Ser Val Cys Ala Ser Thr Asp Asn Gly Ala 65 70 75 80

Glu Ser Asp Arg His Tyr Asp Phe Asp Leu Phe Thr Ile Gly Ala Gly 85 90 95

Ser Gly Gly Val Arg Ala Ser Arg Phe Ala Thr Ser Phe Gly Ala Ser 100 105 110

Ala Ala Val Cys Glu Leu Pro Phe Ser Thr Ile Ser Ser Asp Thr Ala 115 120 125

Gly Gly Val Gly Gly Thr Cys Val Leu Arg Gly Cys Val Pro Lys Lys 130 135 140

Leu Leu Val Tyr Ala Ser Lys Tyr Ser His Glu Phe Glu Asp Ser His 145 150 155 160

Gly Phe Gly Trp Lys Tyr Glu Thr Glu Pro Ser His Asp Trp Thr Thr 165 170 175

Leu Ile Ala Asn Lys Asn Ala Glu Leu Gln Arg Leu Thr Gly Ile Tyr 180 185 190

Lys Asn Ile Leu Ser Lys Ala Asn Val Lys Leu Ile Glu Gly Arg Gly 195 200 205

Lys Val Ile Asp Pro His Thr Val Asp Val Asp Gly Lys Ile Tyr Thr 210 215 220

-117 Thr Arg Asn Ile Leu Ile Ala Val Gly Gly Arg Pro Phe Ile Pro Asp 225 230 235 240

Ile Pro Gly Lys Glu Phe Ala Ile Asp Ser Asp Ala Ala Leu Asp Leu 245 250 255

Pro Ser Lys Pro Lys Lys Ile Ala Ile Val Gly Gly Gly Tyr Ile Ala 260 265 270

Leu Glu Phe Ala Gly Ile Phe Asn Gly Leu Asn Cys Glu Val His Val 275 280 285

Phe Ile Arg Gln Lys Lys Val Leu Arg Gly Phe Asp Glu Asp Val Arg 290 295 300

Asp Phe Val Gly Glu Gln Met Ser Leu Arg Gly Ile Glu Phe His Thr 305 310 315 320

Glu Glu Ser Pro Glu Ala Ile Ile Lys Ala Gly Asp Gly Ser Phe Ser 325 330 335

Leu Lys Thr Ser Lys Gly Thr Val Glu Gly Phe Ser His Val Met Phe 340 345 350

Ala Thr Gly Arg Lys Pro Asn Thr Lys Asn Leu Gly Leu Glu Asn Val 355 360 365

Gly Val Lys Met Ala Lys Asn Gly Ala Ile Glu Val Asp Glu Tyr Ser 370 375 380

Gln Thr Ser Val Pro Ser Ile Trp Ala Val Gly Asp Val Thr Asp Arg 385 390 395 400

Ile Asn Leu Thr Pro Val Ala Leu Met Glu Gly Gly Ala Leu Ala Lys 405 410 415

-118 Thr Leu Phe Gln Asn Glu Pro Thr Lys Pro Asp Tyr Arg Ala Val Pro 420 425 430

Cys Ala Val Phe Ser Gln Pro Pro Ile Gly Thr Val Gly Leu Thr Glu 435 440 445

Glu Gln Ala Ile Glu Gln Tyr Gly Asp Val Asp Val Tyr Thr Ser Asn 450 455 460

Phe Arg Pro Leu Lys Ala Thr Leu Ser Gly Leu Pro Asp Arg Val Phe 465 470 475 480

Met Lys Leu Ile Val Cys Ala Asn Thr Asn Lys Val Leu Gly Val His 485 490 495

Met Cys Gly Glu Asp Ser Pro Glu Ile Ile Gln Gly Phe Gly Val Ala 500 505 510

Val Lys Ala Gly Leu Thr Lys Ala Asp Phe Asp Ala Thr Val Gly Val 515 520 525

His Pro Thr Ala Ala Glu Glu Phe Val Thr Met Arg Ala Pro Thr Arg 530 535 540

Lys Phe Arg Lys Asp Ser Ser Glu Gly Lys Ala Ser Pro Glu Ala Lys 545 550 555 560

Thr Ala Ala Gly Val <210> 21

<211> 1947

<212> DNA

<213> Arabidopsis thaliana

-119 <220> <221> CDS

<222> (1)..(1947)

<223> <400> 21

atg gac gac gta gtt caa tac cgc ctc gag cgg atg gtt gac gag ctt Met Ala Asp Val Val Gln Tyr Arg Leu Glu Arg Met Val Asp Glu Leu 1 5 10 15

get get cta gaa cga age gaa ale ttc act cgt get gag ata gct gag Asp Asp Leu Glu Arg Arg Glu Ile Phe Thr Arg Ala Glu Ile Ala Glu 20 25 30

ale gtg aag cag cgg cgt aag ttt gag tac cgg ctc aag cgt cca agc Ile Val Lys Gln Arg Arg Lys Phe Glu Tyr Arg Leu Lys Arg Pro Ser 35 40 45

cca ctc aaa gaa get ttc ata gac tat att gac tat gag gtt aag ctc Pro Leu Lys Glu Asp Phe Ile Ala Tyr Ile Asp Tyr Glu Val Lys Leu 50 55 60

get gag ctc cgt cag cta cgg agg aaa tag gtg gag cgt gtg act aag Asp Glu Leu Arg Gln Leu Arg Arg Lys Ser Val Ala Arg Val Thr Lys 65 70 75 80

aag age aag aag aaa lea gta let get tEc gac ggt gtg get agg att Lys Arg Lys Lys Lys Ser Val Ser Asp Phe Ala Gly Val Ala Arg Ile 85 90 95

gUt gag att tat age ttg gcg acg aLg agg tat aaa ggt get ale eat Val Glu Ile Tyr Arg Leu Ala Thr Met Arg Tyr Lys Gly Asp Ile Asn 100 105 110

ttg tgg ttt agg tat ctc gag tUt tgt aaa cag aag agg cat gga age Leu Trp Phe Arg Tyr Leu Glu Phe Cys Lys Gln Lys Arg His Gly Arg 115 120 125

-120 atg aaa aag gca ttg gct caa gca ata agg ttt cat cca aaa gtg gct Met Lys Lys Ala Leu Ala Gln Ala Ile Arg Phe His Pro Lys Val Ala 130 135 140

gga gtg tgg ata tat gct gca let tgg gaa tht get age aac ttg eat Gly Val Trp Ile Tyr Ala Ala Ser Trp Glu Phe Asp Arg Asn Leu Asn 145 150 155 160

gtt ace gca gct cgt get ctt aUg ctg eat ggg ctg age gtg tgt lea Val Thr Ala Ala Arg Ala Leu Met Leu Asn Gly Leu Arg Val Cys Ser 165 170 175

aac tat gaa gac ctg tgg gtt gag tat ctg cga atg gaa ctt act tUt Asn Ser Glu Asp Leu Trp Val Glu Tyr Leu Arg Met Glu Leu Thr Phe 180 185 190

cta eat aag ctg aaa gct cgt aaa gtt gcc cUt ggt gaa get aaa gga Leu Asn Lys Leu Lys Ala Arg Lys Val Ala Leu Gly Glu Asp Lys Gly 195 200 205

agt ttg gtg cgt gac acg aaa acc gtt gag get gag caa tgg aaa get Ser Leu Val Arg Asp Thr Lys Thr Val Glu Asp Glu Gln Trp Lys Asp 210 215 220

gag aac aaa gag tta tEt atg tag cta get gag aaa gaa gga eat gaa Glu Asn Lys Glu Leu Phe Met Ser Leu Asp Glu Lys Glu Gly Asn Glu 225 230 235 240

aaa gaa gag eat gac gag gac tat att gtc gaa get gUt gag get gtg Lys Glu Glu Asn Asp Glu Asp Ser Ile Val Glu Asp Val Glu Asp Val 245 250 255

act gag aaa gUt get ttc tta aaa gag aaa ggg tcc eat gEt ctt cag Thr Glu Lys Val Asp Phe Leu Lys Glu Lys Gly Ser Asn Val Leu Gln 260 265 270

acc ale tat agt gga gac gtt gag gct att cca let agt ttt gac ttg Thr Ile Tyr Ser Gly Ala Val Glu Ala Ile Pro Ser Ser Phe Asp Leu 275 280 285

-121 agg aag cgt ttt ttg gag att cta gag gca ace gac tta gcg cat lea Arg Lys Arg Phe Leu Glu Ile Leu Glu Ala Thr Asp Leu Ala His Ser 290 295 300

get gaa atg cgc eat acc att cta agt gac ctg aag cgt get ttt tgc Asp Glu Met Arg Asn Thr Ile Leu Ser Asp Leu Lys Arg Asp Phe Cys 305 310 315 320

eat gaa cct gaa tac tgg eat tgg cUt gca age cat gaa atg agt ggt Asn Glu Pro Glu Tyr Trp Asn Trp Leu Ala Arg His Glu Met Ser Gly 325 330 335

tgt att agc eat gag gca ggc cta gag ttt gca eat cct caa atg caa Cys Ile Ser Asn Glu Ala Gly Leu Glu Phe Ala Asn Pro Gln Met Gln 340 345 350

aag gct att cag gUt ttt gaa gaa ggc ttg caa act ght acg lea agt Lys Ala Ile Gln Val Phe Glu Glu Gly Leu Gln Thr Val Thr Ser Ser 355 360 365

let atg tht gag att tat ata eat ttt ctg atg gag gct att gta cag Ser Met Phe Glu Ile Tyr Ile Asn Phe Leu Met Glu Ala Ile Val Gln 370 375 380

lea aac ggc gac gag eat gaa ale tcc let ttg let eat cag ale att Ser Asn Gly Asp Glu Asn Glu Ile Ser Ser Leu Ser Asn Pro Ile Ile 385 390 395 400

lea cat ale ata aac gtg tac caa aag get get gaa act ggc tgt ttg Ser His Ile Ile Asn Val Tyr Gln Lys Ala Asp Glu Thr Gly Cys Leu 405 410 415

act gaa gag ctt get get gaa tat gtt let ctg tac ttg aaa ctg gaa Thr Glu Glu Leu Ala Asp Glu Tyr Val Ser Leu Tyr Leu Lys Leu Glu 420 425 430

aag act cat gaa get cag aag cta goa gaa aag ctc tgc tat gaa aaa Lys Thr His Glu Ala Gln Lys Leu Ala Glu Lys Leu Cys Ser Glu Lys 435 440 445

-122 ttt gct gga tca gct aag ttg tgg ctt tca aga gtt tcc att gaa ata Phe Ala Gly Ser Ala Lys Leu Trp Leu Ser Arg Val Ser Ile Glu Ile 450 455 460

aga tca ctt tca gag aac tca tct cct agt aaa gca gat tUt cag aca Arg Ser Leu Ser Glu Asn Ser Ser Pro Ser Lys Ala Asp Phe Gln Thr 465 470 475 480

gtc ttt gag ctc cEt tca aat gat ttg agg aaa gta ccg atc tca gaa Val Phe Glu Leu Leu Ser Asn Ala Leu Arg Lys Val Pro Ile Ser Glu 485 490 495

tct gag agc ttg tgg cta atg gat ttt aat tUc ttt gct cat cag cga Ser Glu Ser Leu Trp Leu Met Ala Phe Asn Phe Phe Ala His Gln Arg 500 505 510

act tat ttg gac aaa ctt gta gag aLg tcc atc cta tca gca acc aaa Thr Tyr Leu Asp Lys Leu Val Glu Met Ser Ile Leu Ser Ala Thr Lys 515 520 525

agc cat ggg agc gac cat gtg ttt tct ctt gct tcc aca gtg gtg aaa Ser His Gly Ser Asp His Val Phe Ser Leu Ala Ser Thr Val Val Lys 530 535 540

ttt gtt cht gaa aca aaa ggg gac cac agt gag agg aag ata tac aag Phe Val Leu Glu Thr Lys Gly Ala His Ser Ala Arg Lys Ile Tyr Lys 545 550 555 560

agg tUc ttg gat ctt cat ggt cac agt cht gtt cta tac aaa ggt tgc Arg Phe Leu Ala Leu Pro Gly Pro Ser Leu Val Leu Tyr Lys Gly Cys 565 570 575

att gaa ata gag acc aac ctc ata tca gLa ggt gat aaa gat ggt ctc Ile Glu Ile Glu Thr Asn Leu Ile Ser Val Gly Asp Lys Asp Gly Leu 580 585 590

agt aat gac cgg aag ctg tat gat tat gat gtt gca agt tac ggt caa Ser Asn Ala Arg Lys Leu Tyr Asp Ser Ala Val Ala Ser Tyr Gly Gln 595 600 605

* -123 gac gtg gag ctg tgg aag eat tac tac lea ttg gag ace aag ctg gga Asp Val Glu Leu Trp Lys Asn Tyr Tyr Ser Leu Glu Thr Lys Leu Gly 610 615 620

ace lea gag ace gcc eat gga gtg tat tgg cgt gag age aag act ctg Thr Ser Glu Thr Ala Asn Gly Val Tyr Trp Arg Ala Arg Lys Thr Leu 625 630 635 640

eat gaa tcc gag get ttc ata gtt tga Asn Glu Ser Ala Asp Phe Ile Val <210> 22

<211> 648

<212> PRT

<213> Arabidopsis thaliana <400> 22

Met Ala Asp Val Val Gln Tyr Arg Leu Glu Arg Met Val Asp Glu Leu 1 5 10 15

Asp Asp Leu Glu Arg Arg Glu Ile Phe Thr Arg Ala Glu Ile Ala Glu 20 25 30

Ile Val Lys Gln Arg Arg Lys Phe Glu Tyr Arg Leu Lys Arg Pro Ser 35 40 45

Pro Leu Lys Glu Asp Phe Ile Ala Tyr Ile Asp Tyr Glu Val Lys Leu 50 55 60

Asp Glu Leu Arg Gln Leu Arg Arg Lys Ser Val Ala Arg Val Thr Lys 65 70 75 80

Lys Arg Lys Lys Lys Ser Val Ser Asp Phe Ala Gly Val Ala Arg Ile

-124 85 90 95

Val Glu Ile Tyr Arg Leu Ala Thr Met Arg Tyr Lys Gly Asp Ile Asn 100 105 110

Leu Trp Phe Arg Tyr Leu Glu Phe Cys Lys Gln Lys Arg His Gly Arg 115 120 125

Met Lys Lys Ala Leu Ala Gln Ala Ile Arg Phe His Pro Lys Val Ala 130 135 140

Gly Val Trp Ile Tyr Ala Ala Ser Trp Glu Phe Asp Arg Asn Leu Asn 145 150 155 160

Val Thr Ala Ala Arg Ala Leu Met Leu Asn Gly Leu Arg Val Cys Ser 165 170 175

Asn Ser Glu Asp Leu Trp Val Glu Tyr Leu Arg Met Glu Leu Thr Phe 180 185 190

Leu Asn Lys Leu Lys Ala Arg Lys Val Ala Leu Gly Glu Asp Lys Gly 195 200 205

Ser Leu Val Arg Asp Thr Lys Thr Val Glu Asp Glu Gln Trp Lys Asp 210 215 220

Glu Asn Lys Glu Leu Phe Met Ser Leu Asp Glu Lys Glu Gly Asn Glu 225 230 235 240

Lys Glu Glu Asn Asp Glu Asp Ser Ile Val Glu Asp Val Glu Asp Val 245 250 255

Thr Glu Lys Val Asp Phe Leu Lys Glu Lys Gly Ser Asn Val Leu Gln 260 265 270

Thr Ile Tyr Ser Gly Ala Val Glu Ala Ile Pro Ser Ser Phe Asp Leu 275 280 285

-125 Arg Lys Arg Phe Leu Glu Ile Leu Glu Ala Thr Asp Leu Ala His Ser 290 295 300

Asp Glu Met Arg Asn Thr Ile Leu Ser Asp Leu Lys Arg Asp Phe Cys 305 310 315 320

Asn Glu Pro Glu Tyr Trp Asn Trp Leu Ala Arg His Glu Met Ser Gly 325 330 335

Cys Ile Ser Asn Glu Ala Gly Leu Glu Phe Ala Asn Pro Gln Met Gln 340 345 350

Lys Ala Ile Gln Val Phe Glu Glu Gly Leu Gln Thr Val Thr Ser Ser 355 360 365

Ser Met Phe Glu Ile Tyr Ile Asn Phe Leu Met Glu Ala Ile Val Gln 370 375 380

Ser Asn Gly Asp Glu Asn Glu Ile Ser Ser Leu Ser Asn Pro Ile Ile 385 390 395 400

Ser His Ile Ile Asn Val Tyr Gln Lys Ala Asp Glu Thr Gly Cys Leu 405 410 415

Thr Glu Glu Leu Ala Asp Glu Tyr Val Ser Leu Tyr Leu Lys Leu Glu 420 425 430

Lys Thr His Glu Ala Gln Lys Leu Ala Glu Lys Leu Cys Ser Glu Lys 435 440 445

Phe Ala Gly Ser Ala Lys Leu Trp Leu Ser Arg Val Ser Ile Glu Ile 450 455 460

Arg Ser Leu Ser Glu Asn Ser Ser Pro Ser Lys Ala Asp Phe Gln Thr 465 470 475 480

Val Phe Glu Leu Leu Ser Asn Ala Leu Arg Lys Val Pro Ile Ser Glu

-126 485 490 495

Ser Glu Ser Leu Trp Leu Met Ala Phe Asn Phe Phe Ala His Gln Arg 500 505 510

Thr Tyr Leu Asp Lys Leu Val Glu Met Ser Ile Leu Ser Ala Thr Lys 515 520 525

Ser His Gly Ser Asp His Val Phe Ser Leu Ala Ser Thr Val Val Lys 530 535 540

Phe Val Leu Glu Thr Lys Gly Ala His Ser Ala Arg Lys Ile Tyr Lys 545 550 555 560

Arg Phe Leu Ala Leu Pro Gly Pro Ser Leu Val Leu Tyr Lys Gly Cys 565 570 575

Ile Glu Ile Glu Thr Asn Leu Ile Ser Val Gly Asp Lys Asp Gly Leu 580 585 590

Ser Asn Ala Arg Lys Leu Tyr Asp Ser Ala Val Ala Ser Tyr Gly Gln 595 600 605

Asp Val Glu Leu Trp Lys Asn Tyr Tyr Ser Leu Glu Thr Lys Leu Gly 610 615 620

Thr Ser Glu Thr Ala Asn Gly Val Tyr Trp Arg Ala Arg Lys Thr Leu 625 630 635 640

Asn Glu Ser Ala Asp Phe Ile Val <210> 23

<211> 1866

<212> DNA

-127 <213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1866)

<223> <400> 23

atg tac gga age get cca tgg gga ggt cca ttg gag ata aac act gca Met Tyr Gly Arg Asp Pro Trp Gly Gly Pro Leu Glu Ile Asn Thr Ala 1 5 10 15

get tcc gcc acc gac get get cgt agt cgg eat tta aac get ttg get Asp Ser Ala Thr Asp Asp Asp Arg Ser Arg Asn Leu Asn Asp Leu Asp 20 25 30

cgt gcg get ctt lea cgt cca cta get gag acg cag cag agt tgg tta Arg Ala Ala Leu Ser Arg Pro Leu Asp Glu Thr Gln Gln Ser Trp Leu 35 40 45

ctt ggt cca aeg gag cag aag aag aag aag tac gtc get ctc ggt tgt Leu Gly Pro Thr Glu Gln Lys Lys Lys Lys Tyr Val Asp Leu Gly Cys 50 55 60

att ale gtt agc cgc aag ale tCc gEc tgg act gtt ggt act cEt gtt Ile Ile Val Ser Arg Lys Ile Phe Val Trp Thr Val Gly Thr Leu Val 65 70 75 80

gcc gac gag tta ctc gac gga ttc att acc ttg ale gtt aaa act gtg Ala Ala Ala Leu Leu Ala Gly Phe Ile Thr Leu Ile Val Lys Thr Val 85 90 95

cag cgt cat cat cct aag act cag ccg cag get eat tat act ata gct Pro Arg His His Pro Lys Thr Pro Pro Pro Asp Asn Tyr Thr Ile Ala 100 105 110

-128 cta cac aaa gct cUt aag ttc ttc eat get cag aaa tat ggg aaa ttg Leu His Lys Ala Leu Lys Phe Phe Asn Ala Gln Lys Ser Gly Lys Leu 115 120 125

cca aag cat eat aac gtg lea tgg age ggt eat let ggg ctt caa get Pro Lys His Asn Asn Val Ser Trp Arg Gly Asn Ser Gly Leu Gln Asp 130 135 140

ggg aaa ggt gaa ace gga agc ttc tat aaa get ttg gtg gga ggt tat Gly Lys Gly Glu Thr Gly Ser Phe Tyr Lys Asp Leu Val Gly Gly Tyr 145 150 155 160

tat get get ggt get gct ale aag thc eat ttc ccc atg gct tat gct Tyr Asp Ala Gly Asp Ala Ile Lys Phe Asn Phe Pro Met Ala Tyr Ala 165 170 175

atg act atg ttg agc tgg agt gtt att gaa tat agt gct aaa tac gaa Met Thr Met Leu Ser Trp Ser Val Ile Glu Tyr Ser Ala Lys Tyr Glu 180 185 190

gct get ggt gag ctc act cat gtt aag gag ctt ale aaa tgg gga act Ala Ala Gly Glu Leu Thr His Val Lys Glu Leu Ile Lys Trp Gly Thr 195 200 205

get tac ttt ctc aag act ttc eat agt act gct get tcc att get get Asp Tyr Phe Leu Lys Thr Phe Asn Ser Thr Ala Asp Ser Ile Asp Asp 210 215 220

cUt gtg lea cag gtt gga lea ggg eat act get get gga eat ace get Leu Val Ser Gln Val Gly Ser Gly Asn Thr Asp Asp Gly Asn Thr Asp 225 230 235 240

cat eat gac cat tac tgt tgg atg cga cat gag get atg gac tat aaa Pro Asn Asp His Tyr Cys Trp Met Arg Pro Glu Asp Met Asp Tyr Lys 245 250 255

agg ccc gUg act act tgt eat ggt gga tgt tag get ctc get gca gag Arg Pro Val Thr Thr Cys Asn Gly Gly Cys Ser Asp Leu Ala Ala Glu 260 265 270

-129 atg goa gct get ctg gct lea gca tat att gta ttc aag get aac aag Met Ala Ala Ala Leu Ala Ser Ala Ser Ile Val Phe Lys Asp Asn Lys 275 280 285

gaa tat let aaa aag ctt gtc cat ggt gct aag gtg gtg tat cag tUt Glu Tyr Ser Lys Lys Leu Val His Gly Ala Lys Val Val Tyr Gln Phe 290 295 300

gga agg acg agg age ggg age tat agt goa ggc act gcg gaa let agc Gly Arg Thr Arg Arg Gly Arg Tyr Ser Ala Gly Thr Ala Glu Ser Ser 305 310 315 320

aag ttc tat eat lea agt atg tat tgg get gag ttc att tgg ggt ggt Lys Phe Tyr Asn Ser Ser Met Tyr Trp Asp Glu Phe Ile Trp Gly Gly 325 330 335

gct tgg aUg tat tat gct acc gga eat gta acg tat ctc eat cta ale Ala Trp Met Tyr Tyr Ala Thr Gly Asn Val Thr Tyr Leu Asn Leu Ile 340 345 350

acc caa cat act atg gcc aag cat gct ggt gac ttc tgg ggt ggc cct Thr Gln Pro Thr Met Ala Lys His Ala Gly Ala Phe Trp Gly Gly Pro 355 360 365

tac tat ggt gLa tht agc tgg gac aac aag cEt get ggt gct cag ttg Tyr Tyr Gly Val Phe Ser Trp Asp Asn Lys Leu Ala Gly Ala Gln Leu 370 375 380

ctg ttg agc cgg ttg agg ttg tht ctg agt cct gga tat cca tat gaa Leu Leu Ser Arg Leu Arg Leu Phe Leu Ser Pro Gly Tyr Pro Tyr Glu 385 390 395 400

gaa att cta agg acc tUc cac eat cag acc agc ata gtc atg tgc lea Glu Ile Leu Arg Thr Phe His Asn Gln Thr Ser Ile Val Met Cys Ser 405 410 415

tac ttg cat att tEc aac aaa ttt aac age acc eat gga ggt tta ata Tyr Leu Pro Ile Phe Asn Lys Phe Asn Arg Thr Asn Gly Gly Leu Ile 420 425 430

-130 gag ttg eat cat gga get cca cag ccg ctg caa tat let gta eat gca Glu Leu Asn His Gly Ala Pro Gln Pro Leu Gln Tyr Ser. Val Asn Ala 435 440 445

gct ttc tta gcg act cta tac agt get tat ctg get gct gct get act Ala Phe Leu Ala Thr Leu Tyr Ser Asp Tyr Leu Asp Ala Ala Asp Thr 450 455 460

cct gga tgg tac tgt gga cat eat ttc tat tag ace agt gtg cta cgt Pro Gly Trp Tyr Cys Gly Pro Asn Phe Tyr Ser Thr Ser Val Leu Arg 465 470 475 480

gac ttt gct age tcc cag att get tat ata ctg ggt aaa aac cct cgg Asp Phe Ala Arg Ser Gln Ile Asp Tyr Ile Leu Gly Lys Asn Pro Arg 485 490 495

aaa atg agt tat gtc gUt ggt ttt ggc ace aaa tac cca age cat gtg Lys MetSer Tyr Val Val Gly Phe Gly Thr Lys Tyr Pro Arg His Val 500 505 510

cat cac age gga get leg ata cac aag aac aaa gtc aag tat aac tgc His His Arg Gly Ala Ser Ile Pro Lys Asn Lys Val Lys Tyr Asn Cys 515 520 525

aaa gga gga tgg aaa tgg age gac agc aag aaa cca aac cca aac acg Lys Gly Gly Trp Lys Trp Arg Asp Ser Lys Lys Pro Asn Pro Asn Thr 530 535 540

att gaa gga gcc atg ght get ggt cat gac aag cgc gac ggg tac cgt Ile Glu Gly Ala Met Val Ala Gly Pro Asp Lys Arg Asp Gly Tyr Arg 545 550 555 560

get gtc cgt atg aac tac aac tac act gaa cag act ctt goa ggc eat Asp Val Arg Met Asn Tyr Asn Tyr Thr Glu Pro Thr Leu Ala Gly Asn 565 570 575

get ggt cta gtc gca get cUt gtg goa tta leg ggt gaa gaa gaa gcc Ala Gly Leu Val Ala Ala Leu Val Ala Leu Ser Gly Glu Glu Glu Ala 580 585 590

-131 acc ggt aag ata gac aaa aac act att ttc lea gct gtt cct cct ttg Thr Gly Lys Ile Asp Lys Asn Thr Ile Phe Ser Ala Val Pro Pro Leu 595 600 605

ttc cat act cca cca cct cca cca gca cca tgg aaa cct tga Phe Pro Thr Pro Pro Pro Pro Pro Ala Pro Trp Lys Pro 610 615 620

<210> 24

<211> 621

<212> PRT

<213> Arabidopsis thaliana <400> 24

Met Tyr Gly Arg Asp Pro Trp Gly Gly Pro Leu Glu Ile Asn Thr Ala 1 5 10 15

Asp Ser Ala Thr Asp Asp Asp Arg Ser Arg Asn Leu Asn Asp Leu Asp 20 25 30

Arg Ala Ala Leu Ser Arg Pro Leu Asp Glu Thr Gln Gln Ser Trp Leu 35 40 45

Leu Gly Pro Thr Glu Gln Lys Lys Lys Lys Tyr Val Asp Leu Gly Cys 50 55 60

Ile Ile Val Ser Arg Lys Ile Phe Val Trp Thr Val Gly Thr Leu Val 65 70 75 80

Ala Ala Ala Leu Leu Ala Gly Phe Ile Thr Leu Ile Val Lys Thr Val 85 90 95

Pro Arg His His Pro Lys Thr Pro Pro Pro Asp Asn Tyr Thr Ile Ala 100 105 110

-132 Leu His Lys Ala Leu Lys Phe Phe Asn Ala Gln Lys Ser Gly Lys Leu 115 120 125

Pro Lys His Asn Asn Val Ser Trp Arg Gly Asn Ser Gly Leu Gln Asp 130 135 140

Gly Lys Gly Glu Thr Gly Ser Phe Tyr Lys Asp Leu Val Gly Gly Tyr 145 150 155 160

Tyr Asp Ala Gly Asp Ala Ile Lys Phe Asn Phe Pro Met Ala Tyr Ala 165 170 175

Met Thr Met Leu Ser Trp Ser Val Ile Glu Tyr Ser Ala Lys Tyr Glu 180 185 190

Ala Ala Gly Glu Leu Thr His Val Lys Glu Leu Ile Lys Trp Gly Thr 195 200 205

Asp Tyr Phe Leu Lys Thr Phe Asn Ser Thr Ala Asp Ser Ile Asp Asp 210 215 220

Leu Val Ser Gln Val Gly Ser Gly Asn Thr Asp Asp Gly Asn Thr Asp 225 230 235 240

Pro Asn Asp His Tyr Cys Trp Met Arg Pro Glu Asp Met Asp Tyr Lys 245 250 255

Arg Pro Val Thr Thr Cys Asn Gly Gly Cys Ser Asp Leu Ala Ala Glu 260 265 270

Met Ala Ala Ala Leu Ala Ser Ala Ser Ile Val Phe Lys Asp Asn Lys 275 280 285

Glu Tyr Ser Lys Lys Leu Val His Gly Ala Lys Val Val Tyr Gln Phe 290 295 300

Gly Arg Thr Arg Arg Gly Arg Tyr Ser Ala Gly Thr Ala Glu Ser Ser

-133 305 310 315 320

Lys Phe Tyr Asn Ser Ser Met Tyr Trp Asp Glu Phe Ile Trp Gly Gly 325 330 335

Ala Trp Met Tyr Tyr Ala Thr Gly Asn Val Thr Tyr Leu Asn Leu Ile 340 345 350

Thr Gln Pro Thr Met Ala Lys His Ala Gly Ala Phe Trp Gly Gly Pro 355 360 365

Tyr Tyr Gly Val Phe Ser Trp Asp Asn Lys Leu Ala Gly Ala Gln Leu 370 375 380

Leu Leu Ser Arg Leu Arg Leu Phe Leu Ser Pro Gly Tyr Pro Tyr Glu 385 390 395 400

Glu Ile Leu Arg Thr Phe His Asn Gln Thr Ser Ile Val Met Cys Ser 405 410 415

Tyr Leu Pro Ile Phe Asn Lys Phe Asn Arg Thr Asn Gly Gly Leu Ile 420 425 430

Glu Leu Asn His Gly Ala Pro Gln Pro Leu Gln Tyr Ser Val Asn Ala 435 440 445

Ala Phe Leu Ala Thr Leu Tyr Ser Asp Tyr Leu Asp Ala Ala Asp Thr 450 455 460

Pro Gly Trp Tyr Cys Gly Pro Asn Phe Tyr Ser Thr Ser Val Leu Arg 465 470 475 480

Asp Phe Ala Arg Ser Gln Ile Asp Tyr Ile Leu Gly Lys Asn Pro Arg 485 490 495

Lys Met Ser Tyr Val Val Gly Phe Gly Thr Lys Tyr Pro Arg His Val 500 505 510

-134 His His Arg Gly Ala Ser Ile Pro Lys Asn Lys Val Lys Tyr Asn Cys 515 520 525

Lys Gly Gly Trp Lys Trp Arg Asp Ser Lys Lys Pro Asn Pro Asn Thr 530 535 540

Ile Glu Gly Ala Met Val Ala Gly Pro Asp Lys Arg Asp Gly Tyr Arg 545 550 555 560

Asp Val Arg Met Asn Tyr Asn Tyr Thr Glu Pro Thr Leu Ala Gly Asn 565 570 575

Ala Gly Leu Val Ala Ala Leu Val Ala Leu Ser Gly Glu Glu Glu Ala 580 585 590

Thr Gly Lys Ile Asp Lys Asn Thr Ile Phe Ser Ala Val Pro Pro Leu 595 600 605

Phe Pro Thr Pro Pro Pro Pro Pro Ala Pro Trp Lys Pro 610 615 620

<210> 25

<211> 570

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(570)

<223> <400> 25

-135 atg ttg aag caa gtg gtt gac aag tat let ata ggt aaa gcg gcg att Met Leu Lys Gln Val Val Ala Lys Tyr Ser Ile Gly Lys Ala Ala Ile 1 5 10 15

tat gga agt aac age gaa aag ctt age cct ttc atg tgc caa acc agt Tyr Gly Ser Asn Arg Glu Lys Leu Arg Pro Phe Met Cys Gln Thr Ser 20 25 30

tgt cga ttc cac eat gga cgg act gtt ttt goa cca age agc ttc ttt Cys Arg Phe His Asn Gly Arg Thr Val Phe Ala Pro Arg Ser Phe Phe 35 40 45

ggt gta gaa gac tac gtg get gac gac ace agc cgg cca tac ace tac Gly Val Glu Asp Tyr Val Asp Asp Asp Thr Ser Arg Pro Tyr Thr Tyr 50 55 60

caa aaa gag aaa aag leg aag eat cca gac aag cat gtg leg ttc aag Gln Lys Glu Lys Lys Ser Lys Asn Pro Asp Lys His Val Ser Phe Lys 65 70 75 80

caa cga ace gtt gca tac atg gag ccg ttc act cta get gtc ttc ale Gln Arg Thr Val Ala Tyr Met Glu Pro Phe Thr Leu Asp Val Phe Ile 85 90 95

lea aag cgc ttt gtt tag gca tat ctc acg cac cgt gtt ace tgt agg Ser Lys Arg Phe Val Ser Ala Ser Leu Thr His Arg Val Thr Cys Arg 100 105 110

caa gtt gct gtt gag gga ace aac let aaa gac gLa aaa get ght ctg Gln Val Ala Val Ala Gly Thr Asn Ser Lys Asp Val Lys Ala Val Leu 115 120 125

agg lea age tgt get ale cag gca tgt atg tcc ata ggg agg ale ttg Arg Ser Arg Cys Asp Ile Pro Ala Cys Met Ser Ile Gly Arg Ile Leu 130 135 140

tat gag cgt goa aaa gaa get get gtg tac acg get tat tat acg cca Ser Glu Arg Ala Lys Glu Ala Asp Val Tyr Thr Ala Ser Tyr Thr Pro 145 150 155 160

-136 agg gac caa gac aag ttt gaa ggg aaa ale age gct gtt gtc cag tcc Arg Asp Gln Asp Lys Phe Glu Gly Lys Ile Arg Ala Val Val Gln Ser 165 170 175

ctt att get aac gga att get gtt aaa att tat ctc get tag Leu Ile Asp Asn Gly Ile Asp Val Lys Ile Tyr Leu Asp 180 185

<210> 26

<211> 189

<212> PRT

<213> Arabidopsis thaliana <400> 26

Met Leu Lys Gln Val Val Ala Lys Tyr Ser Ile Gly Lys Ala Ala Ile 1 5 10 15

Tyr Gly Ser Asn Arg Glu Lys Leu Arg Pro Phe Met Cys Gln Thr Ser 20 25 30

Cys Arg Phe His Asn Gly Arg Thr Val Phe Ala Pro Arg Ser Phe Phe 35 40 45

Gly Val Glu Asp Tyr Val Asp Asp Asp Thr Ser Arg Pro Tyr Thr Tyr 50 55 60

Gln Lys Glu Lys Lys Ser Lys Asn Pro Asp Lys His Val Ser Phe Lys 65 70 75 80

Gln Arg Thr Val Ala Tyr Met Glu Pro Phe Thr Leu Asp Val Phe Ile 85 90 95

Ser Lys Arg Phe Val Ser Ala Ser Leu Thr His Arg Val Thr Cys Arg 100 105 110

-137 Gln Val Ala Val Ala Gly Thr Asn Ser Lys Asp Val Lys Ala Val Leu 115 120 125

Arg Ser Arg Cys Asp Ile Pro Ala Cys Met Ser Ile Gly Arg Ile Leu 130 135 140

Ser Glu Arg Ala Lys Glu Ala Asp Val Tyr Thr Ala Ser Tyr Thr Pro 145 150 155 160

Arg Asp Gln Asp Lys Phe Glu Gly Lys Ile Arg Ala Val Val Gln Ser 165 170 175

Leu Ile Asp Asn Gly Ile Asp Val Lys Ile Tyr Leu Asp 180 185

<210> 27

c211> 699 <212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(699)

<223> c400> 27 atg gcc gcc att ace get ctc act ctc cgc let cat gtt tat ctc cca Met Ala Ala Ile Thr Ala Leu Thr Leu Arg Ser Pro Val Tyr Leu Pro 1 5 10 15

lea let gcc ace agc cat age tEc cat ggc ttc acc eat caa cca cca Ser Ser Ala Thr Ser Pro Arg Phe His Gly Phe Thr Asn Gln Pro Pro

-138 20 25 30

cca gct cgt ctc ttc ttt cct ctt aac cac ttc cct let cta lea ale Pro Ala Arg Leu Phe Phe Pro Leu Asn Pro Phe Pro Ser Leu Ser Ile 35 40 45

caa aac cct aaa tcc ale cga att tcc goa tcc gct tag ccg ata ace Gln Asn Pro Lys Ser Ile Arg Ile Ser Ala Ser Ala Ser Pro Ile Thr 50 55 60

ace cca ale ctc cag acg gag aag lea ace gct cgg lea leg ace ctc Thr Pro Ile Leu Gln Thr Glu Lys Ser Thr Ala Arg Ser Ser Thr Leu 65 70 75 80

acc ggg tcc act cgg tat ctc get act ctc gag gct tta goa ale gct Thr Gly Ser Thr Arg Ser Leu Ala Thr Leu Ala Ala Leu Ala Ile Ala 85 90 95

gta acc age gtc cta gct cag aaa ctc let ctc gca ale cag act lea Val Thr Arg Val Leu Ala Gln Lys Leu Ser Leu Ala Ile Gln Thr Ser 100 105 110

agt cac gta ale gcc gac ggg tta cga tUc tat ctc agt acc gcc gga Ser Pro Val Ile Ala Asp Gly Leu Arg Phe Ser Leu Ser Thr Ala Gly 115 120 125

cat gtc tEc ttc gag let ctc cgg get cgt cct cag gga tac ttg aac Pro Val Phe Phe Ala Ser Leu Arg Asp Arg Pro Pro Gly Tyr Leu Asn 130 135 140

aeg ccg ctg acg gtt gtt gcg gtg ggg ata aag aag tgg cta gac att Thr Pro Leu Thr Val Val Ala Val Gly Ile Lys Lys Trp Leu Asp Ile 145 150 155 160

tac agt ggg gLa ttg atg gtt agg gUt ttg ctg agt tgg thc cct eat Tyr Ser Gly Val Leu Met Val Arg Val Leu Leu Ser Trp Phe Pro Asn 165 170 175

ale cat tgg gaa age cag cct ttg tat gcc att age get ctc tgt get Ile Pro Trp Glu Arg Gln Pro Leu Ser Ala Ile Arg Asp Leu Cys Asp

-139 180 185 190

cct tac ttg eat ctc ttc age aac ale att cct cct ale ttc get acg Pro Tyr Leu Asn Leu Phe Arg Asn Ile Ile Pro Pro Ile Phe Asp Thr 195 200 205

ctt get gtt agt cca ttg ctt gct ttc gag gtt cUt ggt ace ctt gga Leu Asp Val Ser Pro Leu Leu Ala Phe Ala Val Leu Gly Thr Leu Gly 210 215 220

leg att gtt cat ggc agc act ggg tag Ser Ile Val His Gly Ser Thr Gly 225 230

<210> 28

<211> 232

<212> PRT

<213> Arabidopsis thaliana <400> 28

Met Ala Ala Ile Thr Ala Leu Thr Leu Arg Ser Pro Val Tyr Leu Pro 1 5 10 15

Ser Ser Ala Thr Ser Pro Arg Phe His Gly Phe Thr Asn Gln Pro Pro 20 25 30

Pro Ala Arg Leu Phe Phe Pro Leu Asn Pro Phe Pro Ser Leu Ser Ile 35 40 45

Gln Asn Pro Lys Ser Ile Arg Ile Ser Ala Ser Ala Ser Pro Ile Thr 50 55 60

Thr Pro Ile Leu Gln Thr Glu Lys Ser Thr Ala Arg Ser Ser Thr Leu 65 70 75 80

-140 Thr Gly Ser Thr Arg Ser Leu Ala Thr Leu Ala Ala Leu Ala Ile Ala 85 90 95

Val Thr Arg Val Leu Ala Gln Lys Leu Ser Leu Ala Ile Gln Thr Ser 100 105 110

Ser Pro Val Ile Ala Asp Gly Leu Arg Phe Ser Leu Ser Thr Ala Gly 115 120 125

Pro Val Phe Phe Ala Ser Leu Arg Asp Arg Pro Pro Gly Tyr Leu Asn 130 135 140

Thr Pro Leu Thr Val Val Ala Val Gly Ile Lys Lys Trp Leu Asp Ile 145 150 155 160

Tyr Ser Gly Val Leu Met Val Arg Val Leu Leu Ser Trp Phe Pro Asn 165 170 175

Ile Pro Trp Glu Arg Gln Pro Leu Ser Ala Ile Arg Asp Leu Cys Asp 180 185 190

Pro Tyr Leu Asn Leu Phe Arg Asn Ile Ile Pro Pro Ile Phe Asp Thr 195 200 205

Leu Asp Val Ser Pro Leu Leu Ala Phe Ala Val Leu Gly Thr Leu Gly 210 215 220

Ser Ile Val His Gly Ser Thr Gly 225 230

<210> 29

<211> 990

<212> DNA

<213> Arabidopsis thaliana

-141 <220> <221> CDS

<222> (1)..(g9O) <223> <400> 29

atg leg lea get tat tgt tcc tcc gcc gUg gct gta tcc gac gca gcc Met Ser Ser Ala Tyr Cys Ser Ser Ala Val Ala Val Ser Ala Ala Ala 1 5 10 15

acc get tcc tcc gcc gct acc ttt eat cca tta ctc tcc tcc cac tcc Thr Ala Ser Ser Ala Ala Thr Phe Asn Pro Leu Leu Ser Ser His Ser 20 25 30

eat tcc caa ctc ttc tat cgc tUt ace cca aaa tcc thc aaa ctc gtt Asn Ser Gln Leu Phe Tyr Arg Phe Thr Pro Lys Ser Phe Lys Leu Val 35 40 45

gac eat tgc cct eat cca cta ale ctc cac lea eat ale cgc cgc cac Ala Asn Cys Pro Asn Pro Leu Ile Leu His Ser Asn Ile Arg Arg His 50 55 60

cgc tUc ttc tgc gcc gac gaa acc gaa get agt tcc gcc get get gaa Arg Phe Phe Cys Ala Ala Glu Thr Glu Ala Ser Ser Ala Asp Asp Glu 65 70 75 80

ale cag goa lea gta gaa gaa gaa gaa gag gta gaa gaa gaa gga get Ile Gln Ala Ser Val Glu Glu Glu Glu Glu Val Glu Glu Glu Gly Asp 85 90 95

gaa ggt gaa gaa gaa gta gag gaa gaa aaa cag acg acg caa gag agt Glu Gly Glu Glu Glu Val Glu Glu Glu Lys Gln Thr Thr Gln Ala Ser 100 105 110

ggt gaa gaa ggg agg cUt tac gtt ggg eat tta cat tac ace ale act Gly Glu Glu Gly Arg Leu Tyr Val Gly Asn Leu Pro Tyr Thr Ile Thr 115 120 125

-142 tct tat gag ctc tct cag att tUt gga gaa gat gga act gtc gtc gat Ser Ser Glu Leu Ser Gln Ile Phe Gly Glu Ala Gly Thr Val Val Asp 130 135 140

gtt cag att gtt tat gat aaa gtt act gat aga agc aga gga ttt gga Val Gln Ile Val Tyr Asp Lys Val Thr Asp Arg Ser Arg Gly Phe Gly 145 150 155 160

ttt gta aca atg gga agc att gaa gaa gct aaa gaa gag atg cag atg Phe Val Thr Met Gly Ser Ile Glu Glu Ala Lys Glu Ala Met Gln Met 165 170 175

ttt aac agc tat caa att ggt ggt aga acg gtg aaa gtg aac ttc cag Phe Asn Ser Ser Gln Ile Gly Gly Arg Thr Val Lys Val Asn Phe Pro 180 185 190

gag gtg ccg aga ggc ggt gag aac gaa gta atg aga acc aaa atc cgt Glu Val Pro Arg Gly Gly Glu Asn Glu Val Met Arg Thr Lys Ile Arg 195 200 205

gat aat aac cgg agt tat gtt gat agt cat cat aag gta tat gca gga Asp Asn Asn Arg Ser Tyr Val Asp Ser Pro His Lys Val Tyr Ala Gly 210 215 220

aac ctt ggt tgg aat cta acc tca caa ggt tta aag gat gca ttt ggt Asn Leu Gly Trp Asn Leu Thr Ser Gln Gly Leu Lys Asp Ala Phe Gly 225 230 235 240

gat caa cat ggt gtg ctt ggt gct aaa gtt atc tat gaa aga aat act Asp Gln Pro Gly Val Leu Gly Ala Lys Val Ile Tyr Glu Arg Asn Thr 245 250 255

ggg agg tat agg ggg ttt ggt tCc atc tcg ttc gag tca gcg gaa aat Gly Arg Ser Arg Gly Phe Gly Phe Ile Ser Phe Glu Ser Ala Glu Asn 260 265 270

gtt cag tct gct ttg gat aca atg aat ggc gtg gaa ght gaa gga cga Val Gln Ser Ala Leu Ala Thr Met Asn Gly Val Glu Val Glu Gly Arg 275 280 285

-143 gcg ctg agg cta eat ttg gct lea gag age gag aaa ccc act gtg let Ala Leu Arg Leu Asn Leu Ala Ser Glu Arg Glu Lys Pro Thr Val Ser 290 295 300

cct cat tcc gLa gaa gaa gga gaa acc gag gag gac agt cta gag agt Pro Pro Ser Val Glu Glu Gly Glu Thr Glu Glu Ala Ser Leu Glu Ser 305 310 315 320

aac gag gtg cht leg eat gtt agt goa tga Asn Glu Val Leu Ser Asn Val Ser Ala <210> 30

<211> 329

<212> PRT

<213> Arabidopsis thaliana <400> 30

Met Ser Ser Ala Tyr Cys Ser Ser Ala Val Ala Val Ser Ala Ala Ala 1 5 10 15

Thr Ala Ser Ser Ala Ala Thr Phe Asn Pro Leu Leu Ser Ser His Ser 20 25 30

Asn Ser Gln Leu Phe Tyr Arg Phe Thr Pro Lys Ser Phe Lys Leu Val 35 40 45

Ala Asn Cys Pro Asn Pro Leu Ile Leu His Ser Asn Ile Arg Arg His 50 55 60

Arg Phe Phe Cys Ala Ala Glu Thr Glu Ala Ser Ser Ala Asp Asp Glu 65 70 75 80

* Ile Gln Ala Ser Val Glu Glu Glu Glu Glu Val Glu Glu Glu Gly Asp

-144 85 90 95

Glu Gly Glu Glu Glu Val Glu Glu Glu Lys Gln Thr Thr Gln Ala Ser 100 105 110

Gly Glu Glu Gly Arg Leu Tyr Val Gly Asn Leu Pro Tyr Thr Ile Thr 115 120 125

Ser Ser Glu Leu Ser Gln Ile Phe Gly Glu Ala Gly Thr Val Val Asp Val Gln Ile Val Tyr Asp Lys Val Thr Asp Arg Ser Arg Gly Phe Gly Phe Val Thr Met Gly Ser Ile Glu Glu Ala Lys Glu Ala Met Gln Met 165 170 175

Phe Asn Ser Ser Gln Ile Gly Gly Arg Thr Val Lys Val Asn Phe Pro 180 185 190

Glu Val Pro Arg Gly Gly Glu Asn Glu Val Met Arg Thr Lys Ile Arg 195 200 205

Asp Asn Asn Arg Ser Tyr Val Asp Ser Pro His Lys Val Tyr Ala Gly Asn Leu Gly Trp Asn Leu Thr Ser Gln Gly Leu Lys Asp Ala Phe Gly Asp Gln Pro Gly Val Leu Gly Ala Lys Val Ile Tyr Glu Arg Asn Thr 245 250 255

Gly Arg Ser Arg Gly Phe Gly Phe Ile Ser Phe Glu Ser Ala Glu Asn 260 265 270

Val Gln Ser Ala Leu Ala Thr Met Asn Gly Val Glu Val Glu Gly Arg 275 280 285

-145 Ala Leu Arg Leu Asn Leu Ala Ser Glu Arg Glu Lys Pro Thr Val Ser 290 295 300

Pro Pro Ser Val Glu Glu Gly Glu Thr Glu Glu Ala Ser Leu Glu Ser 305 310 315 320

Asn Glu Val Leu Ser Asn Val Ser Ala c210> 31 <211> 1539

c212> DNA <213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1539)

<223> <400> 31

atg tgt aaa gag gag aag ttt ctt tat cac agg aaa ctc tgg gag aUg Met Cys Lys Ala Glu Lys Phe Leu Tyr His Arg Lys Leu Trp Glu Met 1 5 10 15

aag gtt aag ttt cta gga get agt aag att gac aag ctt aag aac tcc Lys Val Lys Phe Leu Gly Asp Ser Lys Ile Asp Lys Leu Lys Asn Ser 20 25 30

ttg gtt ttg agg tat cgt atg agc tta tgg atg att cgt get aLg act Leu Val Leu Arg Ser Arg Met Ser Leu Trp Met Ile Arg Ala Met Thr 35 40 45

-146 ata ttg ttg cta tgg agt tgc tUt gtt cat ttg gtt get gtg gga gag Ile Leu Leu Leu Trp Ser Cys Phe Val His Leu Val Ala Val Gly Glu 50 55 60

atg tgg gga cct age ttg ttg aaa ggc tgg cct let tgt ttc eat cac Met Trp Gly Pro Arg Leu Leu Lys Gly Trp Pro Ser Cys Phe Asn His 65 70 75 80

cat gac tUc cac att get gca gaa atg act let ctt ccc atg aaa ale His Asp Phe Pro Ile Ala Ala Glu Met Thr Ser Leu Pro Met Lys Ile 85 90 95

gcc ctc cca cat aaa agg ata tat cag aac eat ggc tat ctt aUg gtt Ala Leu Pro Pro Lys Arg Ile Tyr Gln Asn Asn Gly Tyr Leu Met Val 100 105 110

let tgc eat gga gga ctc aac caa aLg cga gca gag ata tgt get atg Ser Cys Asn Gly Gly Leu Asn Gln Met Arg Ala Ala Ile Cys Asp Met 115 120 125

gtc act att gca age tac atg eat gtc ace cht att gtc cca gag ctt Val Thr Ile Ala Arg Tyr Met Asn Val Thr Leu Ile Val Pro Glu Leu 130 135 140

gac aag acc tag tUt tgg eat get cca agt gag ttc aaa gac ata ttc Asp Lys Thr Ser Phe Trp Asn Asp Pro Ser Glu Phe Lys Asp Ile Phe 145 150 155 160

gac gtg gac cat ttc ata agt tat tta agg gac gag gtt cgt ata cta Asp Val Asp His Phe Ile Ser Ser Leu Arg Asp Glu Val Arg Ile Leu 165 170 175

aaa gag ctt cat cca agg cht aag age agg gtt agg ctc ggg ctg tac Lys Glu Leu Pro Pro Arg Leu Lys Arg Arg Val Arg Leu Gly Leu Tyr 180 185 190

cac acc atg cat cat att agc tgg tcc aac atg tcc tac tac caa gac His Thr Met Pro Pro Ile Ser Trp Ser Asn Met Ser Tyr Tyr Gln Asp 195 200 205

-147 cag att ctt ccg ctg gtg aag aag tat aag gtg gta cat ctg aac aag Gln Ile Leu Pro Leu Val Lys Lys Tyr Lys Val Val His Leu Asn Lys 210 215 220

acc gat act cga ctt gct aat aac gaa cta cct gtt gag att cag aag Thr Asp Thr Arg Leu Ala Asn Asn Glu Leu Pro Val Glu Ile Gln Lys 225 230 235 240

ctg cga tgc cga goa aat ttc aat ggg cUt agg ttt act cca aag att Leu Arg Cys Arg Ala Asn Phe Asn Gly Leu Arg Phe Thr Pro Lys Ile 245 250 255

gag gaa ttg ggt aga aga gta gtc aag att ctc agg gag aaa ggt ccc Glu Glu Leu Gly Arg Arg Val Val Lys Ile Leu Arg Glu Lys Gly Pro 260 265 270

ttt cta gEt ctg cat ctc aga tac gaa atg gat atg ttg gca ttt tct Phe Leu Val Leu His Leu Arg Tyr Glu Met Asp Met Leu Ala Phe Ser 275 280 285

ggt tgc tca cat ggt tgc aac cgc tac gaa gag gaa gaa cta aca aga Gly Cys Ser His Gly Cys Asn Arg Tyr Glu Glu Glu Glu Leu Thr Arg 290 295 300

atg aga tat gct tat ccg tgg tgg aaa gag aaa gta ata gac tcc gag Met Arg Tyr Ala Tyr Pro Trp Trp Lys Glu Lys Val Ile Asp Ser Glu 305 310 315 320

ttg aag agg aaa gaa ggt ctt tgc cca ttg act cct gaa gaa aca gat Leu Lys Arg Lys Glu Gly Leu Cys Pro Leu Thr Pro Glu Glu Thr Ala 325 330 335

ctt acg cta tat goa ttg ggt att gac cga aat gtt cag att tac ata Leu Thr Leu Ser Ala Leu Gly Ile Asp Arg Asn Val Gln Ile Tyr Ile 340 345 350

gat gca gga gaa ata tac ggt ggt aaa agg cgg tta aag gat tta aca Ala Ala Gly Glu Ile Tyr Gly Gly Lys Arg Arg Leu Lys Ala Leu Thr 355 360 365

-148 gat gUt ttt cca aat gtg gUg agg aaa gaa act cta ctc gat tct tct Asp Val Phe Pro Asn Val Val Arg Lys Glu Thr Leu Leu Asp Ser Ser 370 375 380

gat ttg agt ttt tgt aaa aac cat tat tct caa aUg gct gat ctt gat Asp Leu Ser Phe Cys Lys Asn His Ser Ser Gln Met Ala Ala Leu Asp 385 390 395 400

tac ctt atc tct ctc gaa agt gat ata ttc gtt cct act tat tac gga Tyr Leu Ile Ser Leu Glu Ser Asp Ile Phe Val Pro Thr Tyr Tyr Gly 405 410 415

aac atg gag aaa gtc gtg gaa ggt cat cgc agg ttc ttg ggg tUc aag Asn Met Ala Lys Val Val Glu Gly Hls Arg Arg Phe Leu Gly Phe Lys 420 425 430

aag aca att gag cta aac cgg aag ttg ttg gtt aag ctg ata gat gaa Lys Thr Ile Glu Leu Asn Arg Lys Leu Leu Val Lys Leu Ile Asp Glu 435 440 445

tat tat gaa gga ttg ttg agc tgg gaa gtg ttt tca acc acg gtt aag Tyr Tyr Glu Gly Leu Leu Ser Trp Glu Val Phe Ser Thr Thr Val Lys 450 455 460

gcc tht cac gct aca cga atg gga ggg cca aag aga cgg cta gtg att Ala Phe His Ala Thr Arg Met Gly Gly Pro Lys Arg Arg Leu Val Ile 465 470 475 480

cca aat aaa ccg aaa gaa gaa gac tac ttc tat gct aat cca tat gaa Pro Asn Lys Pro Lys Glu Glu Asp Tyr Phe Tyr Ala Asn Pro Tyr Glu 485 490 495

tgt cht cag cta tta cat gag aat aat ggc aat tca cta gaa gaa acc Cys Leu Gln Leu Leu His Glu Asn Asn Gly Asn Ser Leu Glu Glu Thr 500 505 510

taa

-149 <210> 32

<211> 512

<212> PRT

<213> Arabidopsis thaliana <400> 32

Met Cys Lys Ala Glu Lys Phe Leu Tyr His Arg Lys Leu Trp Glu Met 1 5 10 15

Lys Val Lys Phe Leu Gly Asp Ser Lys Ile Asp Lys Leu Lys Asn Ser 20 25 30

Leu Val Leu Arg Ser Arg Met Ser Leu Trp Met Ile Arg Ala Met Thr 35 40 45

Ile Leu Leu Leu Trp Ser Cys Phe Val His Leu Val Ala Val Gly Glu 50 55 60

Met Trp Gly Pro Arg Leu Leu Lys Gly Trp Pro Ser Cys Phe Asn His 65 70 75 80

His Asp Phe Pro Ile Ala Ala Glu Met Thr Ser Leu Pro Met Lys Ile 85 90 95

Ala Leu Pro Pro Lys Arg Ile Tyr Gln Asn Asn Gly Tyr Leu Met Val 100 105 110

Ser Cys Asn Gly Gly Leu Asn Gln Met Arg Ala Ala Ile Cys Asp Met 115 120 125

Val Thr Ile Ala Arg Tyr Met Asn Val Thr Leu Ile Val Pro Glu Leu 130 135 140

Asp Lys Thr Ser Phe Trp Asn Asp Pro Ser Glu Phe Lys Asp Ile Phe 145 150 155 160

-150 Asp Val Asp His Phe Ile Ser Ser Leu Arg Asp Glu Val Arg Ile Leu 165 170 175

Lys Glu Leu Pro Pro Arg Leu Lys Arg Arg Val Arg Leu Gly Leu Tyr 180 185 190

His Thr Met Pro Pro Ile Ser Trp Ser Asn Met Ser Tyr Tyr Gln Asp 195 200 205

Gln Ile Leu Pro Leu Val Lys Lys Tyr Lys Val Val His Leu Asn Lys 210 215 220

Thr Asp Thr Arg Leu Ala Asn Asn Glu Leu Pro Val Glu Ile Gln Lys 225 230 235 240

Leu Arg Cys Arg Ala Asn Phe Asn Gly Leu Arg Phe Thr Pro Lys Ile 245 250 255

Glu Glu Leu Gly Arg Arg Val Val Lys Ile Leu Arg Glu Lys Gly Pro 260 265 270

Phe Leu Val Leu His Leu Arg Tyr Glu Met Asp Met Leu Ala Phe Ser 275 280 285

Gly Cys Ser His Gly Cys Asn Arg Tyr Glu Glu Glu Glu Leu Thr Arg 290 295 300

Met Arg Tyr Ala Tyr Pro Trp Trp Lys Glu Lys Val Ile Asp Ser Glu 305 310 315 320

Leu Lys Arg Lys Glu Gly Leu Cys Pro Leu Thr Pro Glu Glu Thr Ala 325 330 335

Leu Thr Leu Ser Ala Leu Gly Ile Asp Arg Asn Val Gln Ile Tyr Ile 340 345 350

-151 Ala Ala Gly Glu Ile Tyr Gly Gly Lys Arg Arg Leu Lys Ala Leu Thr 355 360 365

Asp Val Phe Pro Asn Val Val Arg Lys Glu Thr Leu Leu Asp Ser Ser 370 375 380

3A8sp Leu Ser Phe Cys Lys Asn His Ser Ser Gln Met Ala Ala Leu Asp Tyr Leu Ile Ser Leu Glu Ser Asp Ile Phe Val Pro Thr Tyr Tyr Gly 405 410 415

Asn Met Ala Lys Val Val Glu Gly His Arg Arg Phe Leu Gly Phe Lys 420 425 430

Lys Thr Ile Glu Leu Asn Arg Lys Leu Leu Val Lys Leu Ile Asp Glu 435 440 445

Tyr Tyr Glu Gly Leu Leu Ser Trp Glu Val Phe Ser Thr Thr Val Lys 450 455 460

Ala Phe His Ala Thr Arg Met Gly Gly Pro Lys Arg Arg Leu Val Ile Pro Asn Lys Pro Lys Glu Glu Asp Tyr Phe Tyr Ala Asn Pro Tyr Glu 485 490 495

Cys Leu Gln Leu Leu His Glu Asn Asn Gly Asn Ser Leu Glu Glu Thr 500 505 510

<210> 33

<211> 993

<212> DNA

<213> Arabidopsis thaliana

-152 <220> <221> CDS

<222> (1)..(993)

<223> <400> 33

aUg gag ttt lea lea caa gac gac get ttt gga gga gac get tcc get Met Glu Phe Ser Ser Gln Asp Asp Asp Phe Gly Gly Asp Asp Ser Ala 1 5 10 15

gct eat gcc acc agg gct lea ggt eat age age agc ttc ggt get cUt Ala Asn Ala Thr Arg Ala Ser Gly Asn Arg Arg Ser Phe Gly Asp Leu 20 25 30

gaa gac get gaa get get att ttc gga lea ace aeg gta gag cat ggt Glu Asp Asp Glu Asp Asp Ile Phe Gly Ser Thr Thr Val Ala Pro Gly 35 40 45

gUt age act ggg atg att ttg tat ctc cga gga agt ctt aag eat tgt Val Arg Thr Gly Met Ile Leu Ser Leu Arg Gly Ser Leu Lys Asn Cys 50 55 60

aaa get get ctt get lea tgt caa eat gag ctc gag lea gca aaa ace Lys Asp Asp Leu Ala Ser Cys Gln Asn Glu Leu Glu Ser Ala Lys Thr 65 70 75 80

gag att cag aag tgg aag lea gcg ttt cag eat gag tcc ttt ght ccc Glu Ile Gln Lys Trp Lys Ser Ala Phe Gln Asn Glu Ser Phe Val Pro 85 90 95

gct gga aaa tat cat gaa cca age ttt ttg att get tat att caa aac Ala Gly Lys Ser Pro Glu Pro Arg Phe Leu Ile Asp Tyr Ile Gln Asn 100 105 110

cta aaa tat tat gag aaa let ttg aaa gaa cag tta gaa ale gca aag Leu Lys Ser Ser Glu Lys Ser Leu Lys Glu Gln Leu Glu Ile Ala Lys 115 120 125

-153 aga aaa gaa gcg lea tgc att gta caa tat gag aaa cgg gaa caa gaa Arg Lys Glu Ala Ser Cys Ile Val Gln Tyr Ala Lys Arg Glu Gln Glu 130 135 140

atg goa gaa ttg aag lea gct gtt cgc get ttg aaa let caa ctc aag Met Ala Glu Leu Lys Ser Ala Val Arg Asp Leu Lys Ser Gln Leu Lys 145 150 155 160

cca gag lea atg cag gcg agg agg ttg tta ctg get cca gca att cat Pro Ala Ser Met Gln Ala Arg Arg Leu Leu Leu Asp Pro Ala Ile His 165 170 175

gaa gaa ttt lea cgt ctg aag eat cta gta gag gaa aaa gac aag aag Glu Glu Phe Ser Arg Leu Lys Asn Leu Val Glu Glu Lys Asp Lys Lys 180 185 190

ale aag gaa ctc cag gac aac att goa goa gtt act ttt act cct caa Ile Lys Glu Leu Gln Asp Asn Ile Ala Ala Val Thr Phe Thr Pro Gln 195 200 205

agc aag eat gga aag atg ctt atg gca aag tgc age acc chg caa gag Ser Lys Asn Gly Lys Met Leu Met Ala Lys Cys Arg Thr Leu Gln Glu 210 215 220

gaa eat gag gag att ggg cac caa get gac gaa gga aag att cat gaa Glu Asn Glu Glu Ile Gly His Gln Ala Ala Glu Gly Lys Ile His Glu 225 230 235 240

cta gca ata aag cEt gca aLg cag aag let caa aac gcg gaa ctt age Leu Ala Ile Lys Leu Ala Met Gln Lys Ser Gln Asn Ala Glu Leu Arg 245 250 255

agt caa tht gaa gga ctg tac aaa cac atg gag gaa tta act eat get Ser Gln Phe Glu Gly Leu Tyr Lys His Met Glu Glu Leu Thr Asn Asp 260 265 270

gtt gag age lea eat gaa acg gtg ata ata ttg caa gag aaa ctg gaa Val Glu Arg Ser Asn Glu Thr Val Ile Ile Leu Gln Glu Lys Leu Glu 275 280 285

-154 gag aaa gag aag gag ata gag age gta aag aaa gga chg gaa att gtg Glu Lys Glu Lys Glu Ile Glu Arg Val Lys Lys Gly Leu Glu Ile Val 290 295 300

let gag cta gta ggt gac aag aaa get gaa gUt get gaa att get gaa Ser Glu Leu Val Gly Asp Lys Lys Asp Glu Val Asp Glu Ile Asp Glu 305 310 315 320

get goa aaa gaa gaa att get ggt gga gaa tag Asp Ala Lys Glu Glu Ile Ala Gly Gly Glu 325 330

<210> 34

<211> 330

<212> PRT

<213> Arabidopsis thaliana <400> 34

Met Glu Phe Ser Ser Gln Asp Asp Asp Phe Gly Gly Asp Asp Ser Ala 1 5 10 15

Ala Asn Ala Thr Arg Ala Ser Gly Asn Arg Arg Ser Phe Gly Asp Leu 20 25 30

Glu Asp Asp Glu Asp Asp Ile Phe Gly Ser Thr Thr Val Ala Pro Gly 35 40 45

Val Arg Thr Gly Met Ile Leu Ser Leu Arg Gly Ser Leu Lys Asn Cys 50 55 60

Lys Asp Asp Leu Ala Ser Cys Gln Asn Glu Leu Glu Ser Ala Lys Thr 65 70 75 80

Glu Ile Gln Lys Trp Lys Ser Ala Phe Gln Asn Glu Ser Phe Val Pro

-155 85 90 95

Ala Gly Lys Ser Pro Glu Pro Arg Phe Leu Ile Asp Tyr Ile Gln Asn 100 105 110

Leu Lys Ser Ser Glu Lys Ser Leu Lys Glu Gln Leu Glu Ile Ala Lys 115 120 125

Arg Lys Glu Ala Ser Cys Ile Val Gln Tyr Ala Lys Arg Glu Gln Glu Met Ala Glu Leu Lys Ser Ala Val Arg Asp Leu Lys Ser Gln Leu Lys Pro Ala Ser Met Gln Ala Arg Arg Leu Leu Leu Asp Pro Ala Ile His 165 170 175

Glu Glu Phe Ser Arg Leu Lys Asn Leu Val Glu Glu Lys Asp Lys Lys 180 185 190

Ile Lys Glu Leu Gln Asp Asn Ile Ala Ala Val Thr Phe Thr Pro Gln 195 200 205

Ser Lys Asn Gly Lys Met Leu Met Ala Lys Cys Arg Thr Leu Gln Glu Glu Asn Glu Glu Ile Gly His Gln Ala Ala Glu Gly Lys Ile His Glu 225 230 235 240

Leu Ala Ile Lys Leu Ala Met Gln Lys Ser Gln Asn Ala Glu Leu Arg 245 250 255

Ser Gln Phe Glu Gly Leu Tyr Lys His Met Glu Glu Leu Thr Asn Asp 260 265 270

Val Glu Arg Ser Asn Glu Thr Val Ile Ile Leu Gln Glu Lys Leu Glu

-156 Glu Lys Glu Lys Glu Ile Glu Arg Val Lys Lys Gly Leu Glu Ile Val 290 295 300

Ser Glu Leu Val Gly Asp Lys Lys Asp Glu Val Asp Glu Ile Asp Glu 305 310 315 320

Asp Ala Lys Glu Glu Ile Ala Gly Gly Glu 325 330

<210> 35

<211> 1335

<212> DNA

<213> Arabidopsis thallana <220> <221> CDS

<222> (1)..(1335)

<223> <400> 35

atg gtg age agg caa gag gag gag aag aag gcg gag aag gga atg cgt Met Val Arg Arg Gln Glu Glu Glu Lys Lys Ala Glu Lys Gly Met Arg 1 5 10 15 ctg ggg aaa tac gag cta ggg agg acg ctc ggc gag ggt eat ttc ggt Leu Gly

Lys Tyr Glu Leu Gly Arg Thr Leu Gly Glu Gly Asn Phe Gly 20 25 30

aaa gtt aaa ttc get aaa get acc gtc tcc ggt cat tcc ttc gac gEt Lys Val Lys Phe Ala Lys Asp Thr Val Ser Gly His Ser Phe Ala Val 35 40 45

-157 aaa ale ale gac aag let cgt ale gac get ctc aac ttc tcc tta cag Lys Ile Ile Asp Lys Ser Arg Ile Ala Asp Leu Asn Phe Ser Leu Gln 50 55 60

ata aaa age gag ale cgg act ctg aaa atg ttg aaa cat ccc cac att Ile Lys Arg Glu Ile Arg Thr Leu Lys Met Leu Lys His Pro His Ile 65 70 75 80

gtt age tta cat gag gtc ttg gct agc aaa acg aaa att eat atg gta Val Arg Leu His Glu Val Leu Ala Ser Lys Thr Lys Ile Asn Met Val 85 90 95

aUg gaa ctt gtt acc gga gga gaa ttg ttc gac age att gUt tcc aac Met Glu Leu Val Thr Gly Gly Glu Leu Phe Asp Arg Ile Val Ser Asn 100 105 110

gga aaa tta ace gaa act get gga age aaa atg ttt cag cag ctt ale Gly Lys Leu Thr Glu Thr Asp Gly Arg Lys Met Phe Gln Gln Leu Ile 115 120 125

get gga ale agc tac tgt cat agc aaa ggt gUt ttc cac agg get ctc Asp Gly Ile Ser Tyr Cys His Ser Lys Gly Val Phe His Arg Asp Leu 130 135 140

aag cta gag eat gEt cUt cht get gca aag gga cat ata aag ale act Lys Leu Glu Asn Val Leu Leu Asp Ala Lys Gly His Ile Lys Ile Thr 145 150 155 160

get tEt ggc ctc agt gct chg cct cag cat ttt agg get gac gga ttg Asp Phe Gly Leu Ser Ala Leu Pro Gln His Phe Arg Asp Asp Gly Leu 165 170 175

ttg cat aac acc tgt gga agt cct eat tac gtt gcg cct gag ght tta Leu His Asn Thr Cys Gly Ser Pro Asn Tyr Val Ala Pro Glu Val Leu 180 185 190

gct aac age ggc tac get ggt goa gca lea gac ata tgg tcc tgt ggt Ala Asn Arg Gly Tyr Asp Gly Ala Ala Ser Asp Ile Trp Ser Cys Gly 195 200 205

-158 gta atc ttg tat gUg att cta acc gga tgt cUt cat ttc gac gac aga Val Ile Leu Tyr Val Ile Leu Thr Gly Cys Leu Pro Phe Asp Asp Arg 210 215 220

aac ctt goa gUt ctt tac cag aag ata tgt aaa gga gac cca cca ata Asn Leu Ala Val Leu Tyr Gln Lys Ile Cys Lys Gly Asp Pro Pro Ile 225 230 235 240

cca aga tgg tta tcc cag ggt goa aga acc aUg att aag aga atg cUt Pro Arg Trp Leu Ser Pro Gly Ala Arg Thr Met Ile Lys Arg Met Leu 245 250 255

gat cca aat cca gtc aeg agg atc aca gtt gtg ggt att aaa gcc agc Asp Pro Asn Pro Val Thr Arg Ile Thr Val Val Gly Ile Lys Ala Ser 260 265 270

gag tgg tEc aaa ctt gag tac att cct tca att cac gat gat gat gac Glu Trp Phe Lys Leu Glu Tyr Ile Pro Ser Ile Pro Asp Asp Asp Asp 275 280 285

gaa gaa gaa gtt gac aca gac gat gat gct ttc tca atc caa gaa ctc Glu Glu Glu Val Asp Thr Asp Asp Asp Ala Phe Ser Ile Gln Glu Leu 290 295 300

gga tca gaa gaa ggg aag ggc agt gat tca cag acc atc atc aat gcg Gly Ser Glu Glu Gly Lys Gly Ser Asp Ser Pro Thr Ile Ile Asn Ala 305 310 315 320

tUt cag tta atc gga atg tat tcc ttt cUt gac ctg tcc ggt ttc ttt Phe Gln Leu Ile Gly Met Ser Ser Phe Leu Asp Leu Ser Gly Phe Phe 325 330 335

gaa caa gag aat gta tca gag agg aga ata aga ttc act tca aat agc Glu Gln Glu Asn Val Ser Glu Arg Arg Ile Arg Phe Thr Ser Asn Ser 340 345 350

tca goa aaa gat tta ctg gag aaa atc gaa aca gcc gtt aca gaa atg Ser Ala Lys Asp Leu Leu Glu Lys Ile Glu Thr Ala Val Thr Glu Met 355 360 365

-159 gga ttc agt gta caa aag aaa cat gcc aag tta age gta aac cag gag Gly Phe Ser Val Gln Lys Lys His Ala Lys Leu Arg Val Asn Gln Glu 370 375 380

gag age acc cag aaa ggt caa gtt ggt tta lea gta ace gct gag gtt Glu Arg Thr Gln Lys Gly Gln Val Gly Leu Ser Val Thr Ala Glu Val 385 390 395 400

ttc gag ata aag cag lea ctg aac gtg gtt gag cta age aaa tat tat Phe Glu Ile Lys Pro Ser Leu Asn Val Val Glu Leu Arg Lys Ser Tyr 405 410 415

ggc get lea tgt tta tat age cag ttg tac gag age cta tta aaa gac Gly Asp Ser Cys Leu Tyr Arg Gln Leu Tyr Glu Arg Leu Leu Lys Asp 420 425 430

gtg ggc ace tcc leg ccg gag caa gag ata gLa act tag Val Gly Thr Ser Ser Pro Glu Gln Glu Ile Val Thr 435 440

<210> 36

<211> 444

<212> PRT

<213> Arabidopsis thaliana <400> 36

Met Val Arg Arg Gln Glu Glu Glu Lys Lys Ala Glu Lys Gly Met Arg 1 5 10 15

Leu Gly Lys Tyr Glu Leu Gly Arg Thr Leu Gly Glu Gly Asn Phe Gly 20 25 30

Lys Val Lys Phe Ala Lys Asp Thr Val Ser Gly His Ser Phe Ala Val 35 40 45

-160 Lys Ile Ile Asp Lys Ser Arg Ile Ala Asp Leu Asn Phe Ser Leu Gln Ile Lys Arg Glu Ile Arg Thr Leu Lys Met Leu Lys His Pro His Ile 65 70 75 80

Val Arg Leu His Glu Val Leu Ala Ser Lys Thr Lys Ile Asn Met Val Met Glu Leu Val Thr Gly Gly Glu Leu Phe Asp Arg Ile Val Ser Asn Gly Lys Leu Thr Glu Thr Asp Gly Arg Lys Met Phe Gln Gln Leu Ile 115 120 125

Asp Gly Ile Ser Tyr Cys His Ser Lys Gly Val Phe His Arg Asp Leu Lys Leu Glu Asn Val Leu Leu Asp Ala Lys Gly His Ile Lys Ile Thr Asp Phe Gly Leu Ser Ala Leu Pro Gln His Phe Arg Asp Asp Gly Leu Leu His Asn Thr Cys Gly Ser Pro Asn Tyr Val Ala Pro Glu Val Leu 180 185 190

Ala Asn Arg Gly Tyr Asp Gly Ala Ala Ser Asp Ile Trp Ser Cys Gly 195 200 205

Val Ile Leu Tyr Val Ile Leu Thr Gly Cys Leu Pro Phe Asp Asp Arg Asn Leu Ala Val Leu Tyr Gln Lys Ile Cys Lys Gly Asp Pro Pro Ile Pro Arg Trp Leu Ser Pro Gly Ala Arg Thr Met Ile Lys Arg Met Leu

-161 Asp Pro Asn Pro Val Thr Arg Ile Thr Val Val Gly Ile Lys Ala Ser Glu Trp Phe Lys Leu Glu Tyr Ile Pro Ser Ile Pro Asp Asp Asp Asp Glu Glu Glu Val Asp Thr Asp Asp Asp Ala Phe Ser Ile Gln Glu Leu Gly Ser Glu Glu Gly Lys Gly Ser Asp Ser Pro Thr Ile Ile Asn Ala Phe Gln Leu Ile Gly Met Ser Ser Phe Leu Asp Leu Ser Gly Phe Phe Glu Gln Glu Asn Val Ser Glu Arg Arg Ile Arg Phe Thr Ser Asn Ser Ser Ala Lys Asp Leu Leu Glu Lys Ile Glu Thr Ala Val Thr Glu Met 355 360 365

Gly Phe Ser Val Gln Lys Lys His Ala Lys Leu Arg Val Asn Gln Glu Glu Arg Thr Gln Lys Gly Gln Val Gly Leu Ser Val Thr Ala Glu Val Phe Glu Ile Lys Pro Ser Leu Asn Val Val Glu Leu Arg Lys Ser Tyr Gly Asp Ser Cys Leu Tyr Arg Gln Leu Tyr Glu Arg Leu Leu y p Val Gly Thr Ser Ser Pro Glu Gln Glu Ile Val Thr

-162 c210> 37 <211> 2145

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(2145)

<223> <400> 37

aUg age aag gga ght cta eat cct gac age get cgt cag ata gtg gaa Met Arg Lys Gly Val Leu Asn Pro Asp Arg Asp Arg Gln Ile Val Glu 1 5 10 15

cat gag ttg cag gaa act ggg ttt agt cca gaa ace gag aaa gtc aag His Glu Leu Gln Glu Thr Gly Phe Ser Pro Glu Thr Glu Lys Val Lys 20 25 30

aac aag eat tUt gaa gaa get gaa gag gaa gaa get gaa tat gtg gag Asn Lys Asn Phe Glu Glu Asp Glu Glu Glu Glu Asp Glu Ser Val Glu 35 40 45

aag ata ttt gag agt age gaa gta cct let tgg aag aag cag ttg acg Lys Ile Phe Glu Ser Arg Glu Val Pro Ser Trp Lys Lys Gln Leu Thr 50 55 60

gtg agg get tht gtg gtg agc tUt aLg cta agc ale ttg tht agt ttc Val Arg Ala Phe Val Val Ser Phe Met Leu Ser Ile Leu Phe Ser Phe 65 70 75 80

att gtt atg aag ctt aac ctc ace acg gga ale ale cct leg ctc eat Ile Val Met Lys Leu Asn Leu Thr Thr Gly Ile Ile Pro Ser Leu Asn 85 90 95

-163 gtc tat gct ggt ctt ttg ggt ttc ttc ttt gtc aag aca tgg act aag Val Ser Ala Gly Leu Leu Gly Phe Phe Phe Val Lys Thr Trp Thr Lys 100 105 110

aLg ctc cat agg tat ggt ctc ttg aaa cag cca ttt act cgc cag gag Met Leu His Arg Ser Gly Leu Leu Lys Gln Pro Phe Thr Arg Gln Glu 115 120 125

aat act gtt att cag acc tgt gtt gtt gcc tat tct ggc att gcc ttc Asn Thr Val Ile Gln Thr Cys Val Val Ala Ser Ser Gly Ile Ala Phe 130 135 140

agc gga ggt ttt ggg aca tac ctc tUt ggc aLg agt gaa cga att gcg Ser Gly Gly Phe Gly Thr Tyr Leu Phe Gly Met Ser Glu Arg Ile Ala 145 150 155 160

acc caa tca gga gat gta tcc cgt ggc gtc aag gac cat tct ttg ggt Thr Gln Ser Gly Asp Val Ser Arg Gly Val Lys Asp Pro Ser Leu Gly 165 170 175

tgg att atc ggt thc ctc ttt gtc gtc agc ttt ctt ggc ctc ttc tca Trp Ile Ile Gly Phe Leu Phe Val Val Ser Phe Leu Gly Leu Phe Ser 180 185 190

gtt gtc ccc ctg cga aag ata aUg gta ata gac ttc aaa cta aca tac Val Val Pro Leu Arg Lys Ile Met Val Ile Asp Phe Lys Leu Thr Tyr 195 200 205

cca agt ggt act goa aca gct cat ctt atc aac agc ttt cac acc act Pro Ser Gly Thr Ala Thr Ala His Leu Ile Asn Ser Phe His Thr Thr 210 215 220

caa ggc gac aag cta gcc aag aaa caa gtg agg gtg ttg ggg aaa ttt Gln Gly Ala Lys Leu Ala Lys Lys Gln Val Arg Val Leu Gly Lys Phe 225 230 235 240

ttc tat tta agc ttc tCc tgg agt ttc tEc caa tgg ttc ttt acc gga Phe Ser Leu Ser Phe Phe Trp Ser Phe Phe Gln Trp Phe Phe Thr Gly 245 250 255

-164 gga gaa aat tgt ggg tUc tcc aac ttc cca aca ttt gga ctc aaa gct Gly Glu Asn Cys Gly Phe Ser Asn Phe Pro Thr Phe Gly Leu Lys Ala 260 265 270

tac cag tac aag ttc tac tht gat tEt tca gca aca tat ght ggt gtt Tyr Gln Tyr Lys Phe Tyr Phe Asp Phe Ser Ala Thr Tyr Val Gly Val 275 280 285

gga atg ata tgt ccg tat ata atc aac atc tct gtc cta ttg gga gga Gly Met Ile Cys Pro Tyr Ile Ile Asn Ile Ser Val Leu Leu Gly Gly 290 295 300

atc ctc tat tgg ggg ata atg tgg ccc ctc att gaa acc aaa aag gga Ile Leu Ser Trp Gly Ile Met Trp Pro Leu Ile Glu Thr Lys Lys Gly 305 310 315 320

gat tgg thc cct gat aat gtc cca tcc agc agc aUg cat ggt ctc caa Asp Trp Phe Pro Asp Asn Val Pro Ser Ser Ser Met His Gly Leu Gln 325 330 335

gct tac aag gtg tEt ata gct gtt gct ata atc cta gga gat ggc tta Ala Tyr Lys Val Phe Ile Ala Val Ala Ile Ile Leu Gly Asp Gly Leu 340 345 350

tac aac ttt tgc aag gtg ctg agc cgg act ctt tca gga tta ttt gta Tyr Asn Phe Cys Lys Val Leu Ser Arg Thr Leu Ser Gly Leu Phe Val 355 360 365

cag ctc cga ggc cat act aca tat att tca aga acc tcc ttc aca ctt Gln Leu Arg Gly Pro Thr Thr Ser Ile Ser Arg Thr Ser Phe Thr Leu 370 375 380

gaa gaa gac cat cat gat tcc cca cta agc cca aag caa tct tat gat Glu Glu Asp Pro His Ala Ser Pro Leu Ser Pro Lys Gln Ser Tyr Asp 385 390 395 400

gac caa cgt cgt aca aga ttc tCc ctc aaa gac caa atc cat act tgg Asp Gln Arg Arg Thr Arg Phe Phe Leu Lys Asp Gln Ile Pro Thr Trp 405 410 415

-165 ttt gct gUt gga ggt tat ale ace ata gct gca ace tat ace gcg ata Phe Ala Val Gly Gly Tyr Ile Thr Ile Ala Ala Thr Ser Thr Ala Ile 420 425 430

ctc cct cac aUg ttc cac cag ctg age tgg tat tac att ctg gEc ale Leu Pro His Met Phe His Gln Leu Arg Trp Tyr Tyr Ile Leu Val Ile 435 440 445

tat ale tgc gcg cct gtc tta gct ttc tgt aac get tat gga gct gga Tyr Ile Cys Ala Pro Val Leu Ala Phe Cys Asn Ala Tyr Gly Ala Gly 450 455 460

ctc ace gac tgg tcc ttg gct lea act tat gga aag tta gcc ata ttc Leu Thr Asp Trp Ser Leu Ala Ser Thr Tyr Gly Lys Leu Ala Ile Phe 465 470 475 480

ace att gga gct tgg gct ggc let gag cac ggt ggt atg ctg get ggt Thr Ile Gly Ala Trp Ala Gly Ser Glu His Gly Gly Met Leu Ala Gly 485 490 495

cta gca gca tgt ggt gOc atg aLg aac ata gtc leg ace get leg get Leu Ala Ala Cys Gly Val Met Met Asn Ile Val Ser Thr Ala Ser Asp 500 505 510

cta ace caa gac tEc aag ace ggc tac ctc act tta lea let cca aag Leu Thr Gln Asp Phe Lys Thr Gly Tyr Leu Thr Leu Ser Ser Pro Lys 515 520 525

lea atg ttt gtg agc caa gtg att gga ace gca aLg ggt tgt gtg gta Ser Met Phe Val Ser Gln Val Ile Gly Thr Ala Met Gly Cys Val Val 530 535 540

let cat tgc gtg tCc tgg cta ttc tac aaa gcg tUt get get tta ggc Ser Pro Cys Val Phe Trp Leu Phe Tyr Lys Ala Phe Asp Asp Leu Gly 545 550 555 560

ctc cca aac act gaa tac cat get cca ttt gct act gta tat cga agc Leu Pro Asn Thr Glu Tyr Pro Ala Pro Phe Ala Thr Val Tyr Arg Ser 565 570 575

-166 atg get aaa cta gga gUg gaa ggt gtc gca let cta ccg age gaa tgt Met Ala Lys Leu Gly Val Glu Gly Val Ala Ser Leu Pro Arg Glu Cys 580 585 590

ctt gtt cta tgc tac gcg ttc tUc ggt gtg gcg att ctc gta aac ata Leu Val Leu Cys Tyr Ala Phe Phe Gly Val Ala Ile Leu Val Asn Ile 595 600. 605

gta aaa get agt ctc cat agc eat tgg gga agg ttc att cca ctt ccc Val Lys Asp Ser Leu His Ser Asn Trp Gly Arg Phe Ile Pro Leu Pro 610 615 620

atg gca atg gct ata ccg ttt tUc ttg gga cct tac ttc gca att gac Met Ala Met Ala Ile Pro Phe Phe Leu Gly Pro Tyr Phe Ala Ile Asp 625 630 635 640

atg tgt gtg gga agt ttg ata ctt ttt ale tgg gaa age gta get gca Met Cys Val Gly Ser Leu Ile Leu Phe Ile Trp Glu Arg Val Asp Ala 645 650 655

gcc aag get gaa gct tht ggg ace gcg gtg gct let ggt ttg ata tgc Ala Lys Ala Glu Ala Phe Gly Thr Ala Val Ala Ser Gly Leu Ile Cys 660 665 670

gga get ggc att tgg let ttg cag agc tcc gtg ctc gct ata gac gga Gly Asp Gly Ile Trp Ser Leu Pro Ser Ser Val Leu Ala Ile Ala Gly 675 680 685

gtt eat cat cat gtt tgc atg aag ttt ctc let tat gca acc eat lea Val Asn Pro Pro Val Cys Met Lys Phe Leu Ser Ser Ala Thr Asn Ser 690 695 700

aag gtc gac aac ttc ctg aaa gga tcc att tea Lys Val Asp Asn Phe Leu Lys Gly Ser Ile 705 710

<210> 38

-167 <211> 714

<212> PRT

<213> Arabidopsis thaliana <400> 38

Met Arg Lys Gly Val Leu Asn Pro Asp Arg Asp Arg Gln Ile Val Gl His Glu Leu Gln Glu Thr Gly Phe Ser Pro Glu Thr Glu Lys Val Lys Asn Lys Asn Phe Glu Glu Asp Glu Glu Glu Glu Asp Glu Ser Val Glu Lys Ile Phe Glu Ser Arg Glu Val Pro Ser Trp Lys Lys Gln Leu Thr Val Arg Ala Phe Val Val Ser Phe Met Leu Ser Ile Leu Phe Ser Phe Ile Val Met Lys Leu Asn Leu Thr Thr Gly Ile Ile Pro Ser Leu Asn Val Ser Ala Gly Leu Leu Gly Phe Phe Phe Val Lys Thr Trp Thr Lys Met Leu His Arg Ser Gly Leu Leu Lys Gln Pro Phe Thr Arg Gln Glu Asn Thr Val Ile Gln Thr Cys Val Val Ala Ser Ser Gly Ile Ala Phe Ser Gly Gly Phe Gly Thr Tyr Leu Phe Gly Met Ser Glu Arg Ile Ala

-168 Thr Gln Ser Gly Asp Val Ser Arg Gly Val Lys Asp Pro Ser Leu Gly 165 170 175

Trp Ile Ile Gly Phe Leu Phe Val Val Ser Phe Leu Gly Leu Phe Ser 180 185 190

Val Val Pro Leu Arg Lys Ile Met Val Ile Asp Phe Lys Leu Thr Tyr 195 200 205

Pro Ser Gly Thr Ala Thr Ala His Leu Ile Asn Ser Phe His Thr Thr 210 215 220

Gln Gly Ala Lys Leu Ala Lys Lys Gln Val Arg Val Leu Gly Lys Phe 225 230 235 240

Phe Ser Leu Ser Phe Phe Trp Ser Phe Phe Gln Trp Phe Phe Thr Gly 245 250 255

Gly Glu Asn Cys Gly Phe Ser Asn Phe Pro Thr Phe Gly Leu Lys Ala 260 265 270

Tyr Gln Tyr Lys Phe Tyr Phe Asp Phe Ser Ala Thr Tyr Val Gly Val 275 280 285

Gly Met Ile Cys Pro Tyr Ile Ile Asn Ile Ser Val Leu Leu Gly Gly 290 295 300

* Ile Leu Ser Trp Gly Ile Met Trp Pro Leu Ile Glu Thr Lys Lys Gly 305 310 315 320

Asp Trp Phe Pro Asp Asn Val Pro Ser Ser Ser Met His Gly Leu Gln 325 330 335

Ala Tyr Lys Val Phe Ile Ala Val Ala Ile Ile Leu Gly Asp Gly Leu 340 345 350

Tyr Asn Phe Cys Lys Val Leu Ser Arg Thr Leu Ser Gly Leu Phe Val 355 360 365

-169 Gln Leu Arg Gly Pro Thr Thr Ser Ile Ser Arg Thr Ser Phe Thr Leu 370 375 380

Glu Glu Asp Pro His Ala Ser Pro Leu Ser Pro Lys Gln Ser Tyr Asp 385 390 395 400

Asp Gln Arg Arg Thr Arg Phe Phe Leu Lys Asp Gln Ile Pro Thr Trp 405 410 415

Phe Ala Val Gly Gly Tyr Ile Thr Ile Ala Ala Thr Ser Thr Ala Ile 420 425 430

Leu Pro His Met Phe His Gln Leu Arg Trp Tyr Tyr Ile Leu Val Ile 435 440 445

Tyr Ile Cys Ala Pro Val Leu Ala Phe Cys Asn Ala Tyr Gly Ala Gly 450 455 460

Leu Thr Asp Trp Ser Leu Ala Ser Thr Tyr Gly Lys Leu Ala Ile Phe 465 470 475 480

Thr Ile Gly Ala Trp Ala Gly Ser Glu His Gly Gly Met Leu Ala Gly 485 490 495

Leu Ala Ala Cys Gly Val Met Met Asn Ile Val Ser Thr Ala Ser Asp 500 505 510

Leu Thr Gln Asp Phe Lys Thr Gly Tyr Leu Thr Leu Ser Ser Pro Lys 515 520 525

Ser Met Phe Val Ser Gln Val Ile Gly Thr Ala Met Gly Cys Val Val 530 535 540

Ser Pro Cys Val Phe Trp Leu Phe Tyr Lys Ala Phe Asp Asp Leu Gly 545 550 555 560

-170 Leu Pro Asn Thr Glu Tyr Pro Ala Pro Phe Ala Thr Val Tyr Arg Ser 565 570 575

Met Ala Lys Leu Gly Val Glu Gly Val Ala Ser Leu Pro Arg Glu Cys Leu Val Leu Cys Tyr Ala Phe Phe Gly Val Ala Ile Leu Val Asn Ile 595 600 605

Val Lys Asp Ser Leu His Ser Asn Trp Gly Arg Phe Ile Pro Leu Pro Met Ala Met Ala Ile Pro Phe Phe Leu Gly Pro Tyr Phe Ala Ile Asp Met Cys Val Gly Ser Leu Ile Leu Phe Ile Trp Glu Arg Val Asp Ala Ala Lys Ala Glu Ala Phe Gly Thr Ala Val Ala Ser Gly Leu Ile Cys Gly Asp Gly Ile Trp Ser Leu Pro Ser Ser Val Leu Ala Ile Ala Gly Val Asn Pro Pro Val Cys Met Lys Phe Leu Ser Ser Ala Thr Asn Ser Lys Val Asp Asn Phe Leu Lys Gly Ser Ile 705 710

<210> 39

<211> 606

<212> DNA

<213> Arabidopsis thaliana

-171 <220> <221> CDS

<222> (1)..(606)

<223> <400> 39

atg tcc gEc gtt ctc aac gcc ggc ttc agt let ccg ctt caa aac age Met Ser Val Val Leu Asn Ala Gly Phe Ser Ser Pro Leu Gln Asn Arg 1 5 10 15

lea cat cat gtt ata cag tta aag cct tag cct ttt gcg lea tac ata Ser His His Val Ile Gln Leu Lys Pro Ser Pro Phe Ala Ser Tyr Ile 20 25 30

let cta aac agt lea age agg lea ctg tta tgc aaa age age ttg gtt Ser Leu Asn Ser Ser Arg Arg Ser Leu Leu Cys Lys Arg Arg Leu Val 35 40 45

gLa let tgt ttg get ace eat gac eat let gtc ace act ace tcc gta Val Ser Cys Leu Asp Thr Asn Asp Asn Ser Val Thr Thr Thr Ser Val 50 55 60

get let tat let tat lea get tat eat aaa cca gta agt gaa lea gUt Asp Ser Ser Ser Ser Ser Asp Ser Asn Lys Pro Val Ser Glu Ser Val 65 70 75 80

gaa lea agc eat ggc act gcc aaa aaa goa cca ttg ace goa cga gag Glu Ser Ser Asn Gly Thr Ala Lys Lys Ala Pro Leu Thr Ala Arg Glu 85 90 95

age cta age gag gct cgt gtt cEt agc cga tac act gaa goa ace cag Arg Leu Arg Ala Ala Arg Val Leu Ser Arg Tyr Thr Glu Ala Thr Pro 100 105 110

aaa cag lea aaa cct aaa atg ggg agc caa cEt cEt get gtg ctc aag Lys Pro Ser Lys Pro Lys Met Gly Ser Gln Leu Leu Asp Val Leu Lys 115 120 125

-172 gaa agt get aag aaa lea aag agg aaa cag ggt cta ccc gaa goa cca Glu Ser Asp Lys Lys Ser Lys Arg Lys Pro Gly Leu Pro Glu Ala Pro 130 135 140

act aac atg ctt get get agc agg age ggg atg cca aag agc ggt ctt Thr Asn Met Leu Asp Asp Ser Arg Arg Gly Met Pro Lys Ser Gly Leu 145 150 155 160

acg ttt get tta ccg gga ggc leg get att ctc ale att gct ttc tcc Thr Phe Asp Leu Pro Gly Gly Ser Asp Ile Leu Ile Ile Ala Phe Ser 165 170 175

tUt gtg ttc ata agc ace gtc atg ttt get act act ttt ctt gtt tgg Phe Val Phe Ile Ser Thr Val Met Phe Ala Thr Thr Phe Leu Val Trp 180 185 190

aaa ctc ggt gcg ata cac ttc aac gaa tag Lys Leu Gly Ala Ile His Phe Asn Glu 195 200

<210> 40

<211> 201

<212> PRT

<213> Arabidopsis thaliana <400> 40

Met Ser Val Val Leu Asn Ala Gly Phe Ser Ser Pro Leu Gln Asn Arg 1 5 10 15

Ser His His Val Ile Gln Leu Lys Pro Ser Pro Phe Ala Ser Tyr Ile 20 25 30

Ser Leu Asn Ser Ser Arg Arg Ser Leu Leu Cys Lys Arg Arg Leu Val 35 40 45

-173 Val Ser Cys Leu Asp Thr Asn Asp Asn Ser Val Thr Thr Thr Ser Val 50 55 60

Asp Ser Ser Ser Ser Ser Asp Ser Asn Lys Pro Val Ser Glu Ser Val 65 70 75 80

Glu Ser Ser Asn Gly Thr Ala Lys Lys Ala Pro Leu Thr Ala Arg Glu 85 90 95

Arg Leu Arg Ala Ala Arg Val Leu Ser Arg Tyr Thr Glu Ala Thr Pro 100 105 110

Lys Pro Ser Lys Pro Lys Met Gly Ser Gln Leu Leu Asp Val Leu Lys 115 120 125

Glu Ser Asp Lys Lys Ser Lys Arg Lys Pro Gly Leu Pro Glu Ala Pro 130 135 140

Thr Asn Met Leu Asp Asp Ser Arg Arg Gly Met Pro Lys Ser Gly Leu 145 150 155 160

Thr Phe Asp Leu Pro Gly Gly Ser Asp Ile Leu Ile Ile Ala Phe Ser 165 170 175

Phe Val Phe Ile Ser Thr Val Met Phe Ala Thr Thr Phe Leu Val Trp 180 185 190

Lys Leu Gly Ala Ile His Phe Asn Glu 195 200

<210> 41

<211> 1992

<212> DNA

<213> Arabidopsis thaliana

-174 <220> <221> CDS

<222> (1)..(1992)

<223> <400> 41

atg gcg agt cta ctc get leg ttg ace acc age ggg ttc ttc acc aUg Met Ala Ser Leu Leu Asp Ser Leu Thr Thr Arg Gly Phe Phe Thr Met 1 5 10 15

ccc lea att let agg att tat let cct cta gct let lea act lea ttg Pro Ser Ile Ser Arg Ile Tyr Ser Pro Leu Ala Ser Ser Thr Ser Leu 20 25 30

act tat lea cca let tcc tat let leg att ale cca tcc ttg lea gtt Thr Ser Ser Pro Ser Ser Ser Ser Ser Ile Ile Pro Ser Leu Ser Val 35 40 45

ctc let tac act cac caa cac cag cat tcc let cgc ttc cct ttc ctt Leu Ser Tyr Thr Hls Gln His Pro Hls Ser Ser Arg Phe Pro Phe Leu 50 55 60

gtt gca goa act ctg get ggt tcc let gct gag gaa gag cta get ttc Val Ala Ala Thr Leu Asp Gly Ser Ser Ala Glu Glu Glu Leu Asp Phe 65 70 75 80

gag gaa tUc gac caa tat gct gaa get aac ttc goa get get tat leg Glu Glu Phe Asp Gln Tyr Ala Glu Asp Asn Phe Ala Asp Asp Tyr Ser 85 90 95

get gac gaa gac gac tcc ale get ale tcc ght ctt gag aaa gaa gcg Asp Asp Glu Asp Asp Ser Ile Asp Ile Ser Val Leu Glu Lys Glu Ala 100 105 110

age get ale gtg age get tat get acc act ctg let cgc gag ctc aaa

-175 Arg Asp Ile Val Arg Asp Tyr Ala Thr Thr Leu Ser Arg Glu Leu Lys 115 120 125

ale gag get gag acc att gag ggg aag gaa act cgt age aaa ggg aaa Ile Glu Asp Glu Thr Ile Glu Gly Lys Glu Thr Arg Arg Lys Gly Lys 130 135 140

agg cta gac aaa eat ace cag cag ata cca gag cat ctt ctc caa age Arg Leu Ala Lys Asn Thr Gln Gln Ile Pro Glu His Leu Leu Gln Arg 145 150 155 160

gtt gct ata gtt gga agg cat eat gtc gga aaa lea gca ttg ttc aac Val Ala Ile Val Gly Arg Pro Asn Val Gly Lys Ser Ala Leu Phe Asn 165 170 175

cgc ctt gtt ggg gag eat age gct att gta gtg get gaa cct gga gtt Arg Leu Val Gly Glu Asn Arg Ala Ile Val Val Asp Glu Pro Gly Val 180 185 190

act agg get cga ttg tat ggt age lea tat tgg ggt get caa gag ttt Thr Arg Asp Arg Leu Tyr Gly Arg Ser Tyr Trp Gly Asp Gln Glu Phe 195 200 205

gtg gtg gta gac acc gga gga gtt aLg act gtt lea aag lea cca tat Val Val Val Asp Thr Gly Gly Val Met Thr Val Ser Lys Ser Pro Ser 210 215 220

ggt gtc atg gaa gag ctg eat gtg lea acc acc att ggc atg gaa ggt Gly Val Met Glu Glu Leu Asn Val Ser Thr Thr Ile Gly Met Glu Gly 225 230 235 240

att cca cta agc let agg gaa goa gct att goa agg atg cat tcc atg Ile Pro Leu Ser Ser Arg Glu Ala Ala Ile Ala Arg Met Pro Ser Met 245 250 255

att gag aaa caa get ace goa gct gtc gac gaa lea get gtt att att Ile Glu Lys Gln Ala Thr Ala Ala Val Asp Glu Ser Ala Val Ile Ile 260 265 270

ttc gtt gEc get ggc cag goa ggg cca lea ggt get get gUg gaa att

-176 Phe Val Val Asp Gly Gln Ala Gly Pro Ser Gly Ala Asp Val Glu Ile 275 280 285

gca gac tgg ttg cgg aag tac tac lea cat aag tat ale att ctc gcg Ala Asp Trp Leu Arg Lys Tyr Tyr Ser Hls Lys Tyr Ile Ile Leu Ala 290 295 300

gtg aac aag tgt gaa leg cca cgt aaa gga ctc atg cag gct tag gaa Val Asn Lys Cys Glu Ser Pro Arg Lys Gly Leu Met Gln Ala Ser Glu 305 310 315 320

ttt tgg let cta ggg thc ace cct ale cct ale tat gca ttg tag gga Phe Trp Ser Leu Gly Phe Thr Pro Ile Pro Ile Ser Ala Leu Ser Gly 325 330 335

act gga ace gga gag ctg ctt get ctt gtt tgt let ggc cta att aaa Thr Gly Thr Gly Glu Leu Leu Asp Leu Val Cys Ser Gly Leu Ile Lys 340 345 350

ctc gag ale atg gag aac att gaa gag gag gaa gaa gaa aac tac att Leu Glu Ile Met Glu Asn Ile Glu Glu Glu Glu Glu Glu Asn Tyr Ile 355 360 365

cat gac att goa att att ggt cgg cca eat gtt ggc aaa agt agc att Pro Ala Ile Ala Ile Ile Gly Arg Pro Asn Val Gly Lys Ser Ser Ile 370 375 380

tta eat gca cEt gtc cga gag get age ace att gUt agc cat gtt agt Leu Asn Ala Leu Val Arg Glu Asp Arg Thr Ile Val Ser Pro Val Ser 385 390 395 400

ggc act acc cgt get gct ata get goa gaa tUt acc gga cca get ggg Gly Thr Thr Arg Asp Ala Ile Asp Ala Glu Phe Thr Gly Pro Asp Gly 405 410 415

gag aag tEt cgg ctt ata get ace gct ggg ale agg aaa aag lea tat Glu Lys Phe Arg Leu Ile Asp Thr Ala Gly Ile Arg Lys Lys Ser Ser 420 425 430

gtg gct lea lea ggc agc act ace gag gcc atg lea gtg eat cgt gca

-177 Val Ala Ser Ser Gly Ser Thr Thr Glu Ala Met Ser Val Asn Arg Ala 435 440 445

ttt cga gca att cgt cgt tat get gtt gtt gcc ctt gtc att gaa gct Phe Arg Ala Ile Arg Arg Ser Asp Val Val Ala Leu Val Ile Glu Ala 450 455 460

atg gca tgc ata ace gag cag get ctg aag att goa gaa age ata gaa Met Ala Cys Ile Thr Glu Gln Asp Leu Lys Ile Ala Glu Arg Ile Glu 465 470 475 480

age gaa ggg aaa gga tgt chg ght gtt gta aac aaa tgg get ace ata Arg Glu Gly Lys Gly Cys Leu Val Val Val Asn Lys Trp Asp Thr Ile 485 490 495

cag aac aaa aac caa gag act goa gca cat tac gag gac get gtt cgg Pro Asn Lys Asn Gln Glu Thr Ala Ala His Tyr Glu Asp Asp Val Arg 500 505 510

gag aag ctc cgt tcc ctc aaa tgg gca cat att gtt tat lea acc gca Glu Lys Leu Arg Ser Leu Lys Trp Ala Pro Ile Val Tyr Ser Thr Ala 515 520 525

ata act ggc cat agc ght gac eat att gtg gtt get gct get acg gtt Ile Thr Gly His Ser Val Asp Asn Ile Val Val Ala Ala Ala Thr Val 530 535 540

caa aag gag age lea age age ctt agt acg gct ata ttg aac caa gUg Gln Lys Glu Arg Ser Arg Arg Leu Ser Thr Ala Ile Leu Asn Gln Val 545 550 555 560

ata age gaa gca ght gca tEt aaa tcc cat cca agg acc cgt gga ggc Ile Arg Glu Ala Val Ala Phe Lys Ser Pro Pro Arg Thr Arg Gly Gly 565 570 575

aag cga ggt cgc gEt tac tat tgc acc cag goa gca ata agg cca cag Lys Arg Gly Arg Val Tyr Tyr Cys Thr Gln Ala Ala Ile Arg Pro Pro 580 585 590

acg ttt gtt ttc ttt gta aac gac gca aag ctg ttt leg get acg tac

-178 Thr Phe Val Phe Phe Val Asn Asp Ala Lys Leu Phe Ser Asp Thr Tyr 595 600 605

age agg tat atg gag aaa cag cta cgc act get gca ggc ttt get ggg Arg Arg Tyr Met Glu Lys Gln Leu Arg Thr Asp Ala Gly Phe Ala Gly 610 615 620

act cca att cgg ctt ctt tgg cgt agc cgt aaa age let gac aaa eat Thr Pro Ile Arg Leu Leu Trp Arg Ser Arg Lys Arg Ser Asp Lys Asn 625 630 635 640

gga gga ggt gga gga ace aLg age atg gca ggc cUt ace cgt cag age Gly Gly Gly Gly Gly Thr Met Arg Met Ala Gly Leu Thr Arg Gln Arg 645 650 655

eat ctt gca acc aaa age ace tea Asn Leu Ala Thr Lys Arg Thr <210> 42

<211> 663

<212> PRT

<213> Arabidopsis thaliana <400> 42

Met Ala Ser Leu Leu Asp Ser Leu Thr Thr Arg Gly Phe Phe Thr Met 1 5 10 15

Pro Ser Ile Ser Arg Ile Tyr Ser Pro Leu Ala Ser Ser Thr Ser Leu 20 25 30

Thr Ser Ser Pro Ser Ser Ser Ser Ser Ile Ile Pro Ser Leu Ser Val 35 40 45

Leu Ser Tyr Thr His Gln His Pro His Ser Ser Arg Phe Pro Phe Leu 50 55 60

-179 Val Ala Ala Thr Leu Asp Gly Ser Ser Ala Glu Glu Glu Leu Asp Phe Glu Glu Phe Asp Gln Tyr Ala Glu Asp Asn Phe Ala Asp Asp Tyr Ser Asp Asp Glu Asp Asp Ser Ile Asp Ile Ser Val Leu Glu Lys Glu Ala Arg Asp Ile Val Arg Asp Tyr Ala Thr Thr Leu Ser Arg Glu Leu Lys Ile Glu Asp Glu Thr Ile Glu Gly Lys Glu Thr Arg Arg Lys Gly Lys Arg Leu Ala Lys Asn Thr Gln Gln Ile Pro Glu His Leu Leu Gln Arg Val Ala Ile Val Gly Arg Pro Asn Val Gly Lys Ser Ala Leu Phe Asn Arg Leu Val Gly Glu Asn Arg Ala Ile Val Val Asp Glu Pro Gly Val Thr Arg Asp Arg Leu Tyr Gly Arg Ser Tyr Trp Gly Asp Gln Glu Phe Val Val Val Asp Thr Gly Gly Val Met Thr Val Ser Lys Ser Pro Ser Gly Val Met Glu Glu Leu Asn Val Ser Thr Thr Ile Gly Met Glu Gly Ile Pro Leu Ser Ser Arg Glu Ala Ala Ile Ala Arg Met Pro Ser Met 245 250 255

-180 Ile Glu Lys Gln Ala Thr Ala Ala Val Asp Glu Ser Ala Val Ile Ile 260 265 270

Phe Val Val Asp Gly Gln Ala Gly Pro Ser Gly Ala Asp Val Glu Ile 275 280 285

Ala Asp Trp Leu Arg Lys Tyr Tyr Ser His Lys Tyr Ile Ile Leu Ala 290 295 300

Val Asn Lys Cys Glu Ser Pro Arg Lys Gly Leu Met Gln Ala Ser Glu 305 310 315 320

Phe Trp Ser Leu Gly Phe Thr Pro Ile Pro Ile Ser Ala Leu Ser Gly 325 330 335

Thr Gly Thr Gly Glu Leu Leu Asp Leu Val Cys Ser Gly Leu Ile Lys 340 345 350

Leu Glu Ile Met Glu Asn Ile Glu Glu Glu Glu Glu Glu Asn Tyr Ile 355 360 365

Pro Ala Ile Ala Ile Ile Gly Arg Pro Asn Val Gly Lys Ser Ser Ile 370 375 380

Leu Asn Ala Leu Val Arg Glu Asp Arg Thr Ile Val Ser Pro Val Ser 385 390 395 400

Gly Thr Thr Arg Asp Ala Ile Asp Ala Glu Phe Thr Gly Pro Asp Gly 405 410 415

Glu Lys Phe Arg Leu Ile Asp Thr Ala Gly Ile Arg Lys Lys Ser Ser 420 425 430

Val Ala Ser Ser Gly Ser Thr Thr Glu Ala Met Ser Val Asn Arg Ala 435 440 445

Phe Arg Ala Ile Arg Arg Ser Asp Val Val Ala Leu Val Ile Glu Ala 450 455 460

-181 Met Ala Cys Ile Thr Glu Gln Asp Leu Lys Ile Ala Glu Arg Ile Glu Arg Glu Gly Lys Gly Cys Leu Val Val Val Asn Lys Trp Asp Thr Ile Pro Asn Lys Asn Gln Glu Thr Ala Ala His Tyr Glu Asp Asp Val Arg Glu Lys Leu Arg Ser Leu Lys Trp Ala Pro Ile Val Tyr Ser Thr Ala 515 520 525

Ile Thr Gly His Ser Val Asp Asn Ile Val Val Ala Ala Ala Thr Val Gln Lys Glu Arg Ser Arg Arg Leu Ser Thr Ala Ile Leu Asn Gln Val Ile Arg Glu Ala Val Ala Phe Lys Ser Pro Pro Arg Thr Arg Gly Gly Lys Arg Gly Arg Val Tyr Tyr Cys Thr Gln Ala Ala Ile Arg Pro Pro 580 585 590

Thr Phe Val Phe Phe Val Asn Asp Ala Lys Leu Phe Ser Asp Thr Tyr Arg Arg Tyr Met Glu Lys Gln Leu Arg Thr Asp Ala Gly Phe Ala Gly Thr Pro Ile ArgLeu Leu Trp Arg Ser Arg Lys Arg Ser Asp Lys Asn Gly Gly Gly Gly Gly Thr Met Arg Met Ala Gly Leu Thr Arg Gln Arg

-182 Asn Leu Ala Thr Lys Arg Thr <210> 43

<211> 1461

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1461)

<223> <400> 43

atg gag lea aUg let ctc tcc ttt let let leg cta tgt lea tcc age Met Ala Ser Met Ser Leu Ser Phe Ser Ser Ser Leu Cys Ser Ser Arg 1 5 10 15

ale ccc gaa ggt aag cgt agg ttt cgt cac age get gtg ggc ale ght Ile Pro Glu Gly Lys Arg Arg Phe Arg His Arg Asp Val Gly Ile Val 20 25 30

age tgc gEt ttg gct get leg aaa let let cag gga agt gtt acg aag Arg Cys Val Leu Ala Ala Ser Lys Ser Ser Pro Gly Ser Val Thr Lys 35 40 45

aag agg cUt tgg aaa gac ggc gaa ttc ccc gga ale acg gag cag gEt Lys Arg Leu Trp Lys Asp Gly Glu Phe Pro Gly Ile Thr Glu Pro Val 50 55 60

eat cag age age act cag ata aag eat gUg aag aag aaa ctt gac agg Asn Gln Arg Arg Thr Pro Ile Lys Asn Val Lys Lys Lys Leu Asp Arg 65 70 75 80

-183 aga agc aaa gct aac gga tgg gtt aac acc gtc act gaa act ttg tcc Arg Ser Lys Ala Asn Gly Trp Val Asn Thr Val Thr Glu Thr Leu Ser 85 90 95

get ctc ale gcc aaa aag cag tgg tta caa gct ctc gag gEt ttt get Asp Leu Ile Ala Lys Lys Gln Trp Leu Gln Ala Leu Glu Val Phe Asp 100 105 110

atg ttg agg gaa caa ace ttt tat caa cca aag gaa gga act tac aUg Met Leu Arg Glu Gln Thr Phe Tyr Gln Pro Lys Glu Gly Thr Tyr Met 115 120 125

aag ctg ctt gUt cEt ctc ggt aaa tat ggt caa cac eat cgt gca cag Lys Leu Leu Val Leu Leu Gly Lys Ser Gly Gln Pro Asn Arg Ala Gln 130 135 140

aag ctg ttc gac gaa atg ctt gaa gaa gga ctt gaa cca act gtt gaa Lys Leu Phe Asp Glu Met Leu Glu Glu Gly Leu Glu Pro Thr Val Glu 145 150 155 160

ctc tac act gct cUt ctc gct gct tac act cgc agc eat ctc ale gac Leu Tyr Thr Ala Leu Leu Ala Ala Tyr Thr Arg Ser Asn Leu Ile Asp 165 170 175

get gct tEt lea att cht get aaa atg aaa agc tEt cct caa tgc caa Asp Ala Phe Ser Ile Leu Asp Lys Met Lys Ser Phe Pro Gln Cys Gln 180 185 190

cat get gEt tUc aeg tac agc act ctg ctc aag get tgt gtg get gct Pro Asp Val Phe Thr Tyr Ser Thr Leu Leu Lys Ala Cys Val Asp Ala 195 200 205

tat cag tUt gac ttg gtg get tag tta tac aag gaa atg gac gag cgt Ser Gln Phe Asp Leu Val Asp Ser Leu Tyr Lys Glu Met Asp Glu Arg 210 215 220

ttg ata act cca aac act gtg acc cag aac ata gtt tta agt ggg tac Leu Ile Thr Pro Asn Thr Val Thr Gln Asn Ile Val Leu Ser Gly Tyr 225 230 235 240

-184 ggt agg gtc gga agg ttt get cag atg gag aaa gtt ttg tat get atg Gly Arg Val Gly Arg Phe Asp Gln Met Glu Lys Val Leu Ser Asp Met 245 250 255

ttg gtg agt act gct tgc aaa ccc get gtg tgg act atg eat ale ale Leu Val Ser Thr Ala Cys Lys Pro Asp Val Trp Thr Met Asn Ile Ile 260 265 270

ctt agt gUg tht gga aac aLg ggt aag ata gac atg atg gag agc tgg Leu Ser Val Phe Gly Asn Met Gly Lys Ile Asp Met Met Glu Ser Trp 275 280 285

tac gaa aag ttc agg aac ttt ggg att gag cca gag act cgg act ttc Tyr Glu Lys Phe Arg Asn Phe Gly Ile Glu Pro Glu Thr Arg Thr Phe 290 295 300

eat att ttg att ggt let tat ggg aag aag age atg tat get aag atg Asn Ile Leu Ile Gly Ser Tyr Gly Lys Lys Arg Met Tyr Asp Lys Met 305 310 315 320

leg tat gtc atg gaa tac atg cga aag cta gag tUt cag tgg ace ace Ser Ser Val Met Glu Tyr Met Arg Lys Leu Glu Phe Pro Trp Thr Thr 325 330 335

lea acc tac aac eat ale ale gag gcg ttt gag get gtt ggt get gca Ser Thr Tyr Asn Asn Ile Ile Glu Ala Phe Ala Asp Val Gly Asp Ala 340 345 350

aag aac atg gag ttg ace ttt get cag aLg cgt agc gaa ggt atg aaa Lys Asn Met Glu Leu Thr Phe Asp Gln Met Arg Ser Glu Gly Met Lys 355 360 365

goa gac ace aag acc ttt tgc tgt ctc ata aac gga tat gac eat gcc Ala Asp Thr Lys Thr Phe Cys Cys Leu Ile Asn Gly Tyr Ala Asn Ala 370 375 380

ggt ctt ttc cac aag gUg ata agt agt gtt cag ttg gct gct aag tEt Gly Leu Phe His Lys Val Ile Ser Ser Val Gln Leu Ala Ala Lys Phe 385 390 395 400

-185 gag ata ccc gag eat act gcc ttt tac aac gcg gtg ata lea gag tgt Glu Ile Pro Glu Asn Thr Ala Phe Tyr Asn Ala Val Ile Ser Ala Cys 405 410 415

gct aaa gca get get ctg ata gag atg gaa age gtg tac ata age atg Ala Lys Ala Asp Asp Leu Ile Glu Met Glu Arg Val Tyr Ile Arg Met 420 425 430

aag gag age caa tgc gta tgc get lea age acg ttt gag ale aUg gtc Lys Glu Arg Gln Cys Val Cys Asp Ser Arg Thr Phe Glu Ile Met Val 435 440 445

gag gcg tat gaa aaa gaa ggt atg eat get aag ale tat tac ttg gaa Glu Ala Tyr Glu Lys Glu Gly Met Asn Asp Lys Ile Tyr Tyr Leu Glu 450 455 460

caa gag agg caa aag ctt atg get cgc act gtt gct ace aaa gag atg Gln Glu Arg Gln Lys Leu Met Asp Arg Thr Val Ala Thr Lys Glu Met 465 470 475 480

gag eat ctt ccg goa gga tga Glu Asn Leu Pro Ala Gly <210> 44

<211> 486

<212> PRT

<213> Arabidopsis thaliana <400> 44

Met Ala Ser Met Ser Leu Ser Phe Ser Ser Ser Leu Cys Ser Ser Arg 1 5 10 15

Ile Pro Glu Gly Lys Arg Arg Phe Arg His Arg Asp Val Gly Ile Val 20 25 30

-186 Arg Cys Val Leu Ala Ala Ser Lys Ser Ser Pro Gly Ser Val Thr Lys Lys Arg Leu Trp Lys Asp Gly Glu Phe Pro Gly Ile Thr Glu Pro Val Asn Gln Arg Arg Thr Pro Ile Lys Asn Val Lys Lys Lys Leu Asp Arg Arg Ser Lys Ala Asn Gly Trp Val Asn Thr Val Thr Glu Thr Leu Ser 85 90 95

Asp Leu Ile Ala Lys Lys Gln Trp Leu Gln Ala Leu Glu Val Phe Asp Met Leu Arg Glu Gln Thr Phe Tyr Gln Pro Lys Glu Gly Thr Tyr Met 115 120 125

Lys Leu Leu Val Leu Leu Gly Lys Ser Gly Gln Pro Asn Arg Ala Gln Lys Leu Phe Asp Glu Met Leu Glu Glu Gly Leu Glu Pro Thr Val Glu Leu Tyr Thr Ala Leu Leu Ala Ala Tyr Thr Arg Ser Asn Leu Ile Asp 165 170 175

Asp Ala Phe Ser Ile Leu Asp Lys Met Lys Ser Phe Pro Gln Cys Gln 180 185 190

Pro Asp Val Phe Thr Tyr Ser Thr Leu Leu Lys Ala Cys Val Asp Ala Ser Gln Phe Asp Leu Val Asp Ser Leu Tyr Lys Glu Met Asp Glu Arg Leu Ile Thr Pro Asn Thr Val Thr Gln Asn Ile Val Leu Ser Gly Tyr

-187 225 230 235 240

Gly Arg Val Gly Arg Phe Asp Gln Met Glu Lys Val Leu Ser Asp Met 245 250 255

Leu Val Ser Thr Ala Cys Lys Pro Asp Val Trp Thr Met Asn Ile Ile 260 265 270

Leu Ser Val Phe Gly Asn Met Gly Lys Ile Asp Met Met Glu Ser Trp 275 280 285

Tyr Glu Lys Phe Arg Asn Phe Gly Ile Glu Pro Glu Thr Arg Thr Phe 290 295 300

Asn Ile Leu Ile Gly Ser Tyr Gly Lys Lys Arg Met Tyr Asp Lys Met 305 310 315 320

Ser Ser Val Met Glu Tyr Met Arg Lys Leu Glu Phe Pro Trp Thr Thr 325 330 335

Ser Thr Tyr Asn Asn Ile Ile Glu Ala Phe Ala Asp Val Gly Asp Ala 340 345 350

Lys Asn Met Glu Leu Thr Phe Asp Gln Met Arg Ser Glu Gly Met Lys 355 360 365

Ala Asp Thr Lys Thr Phe Cys Cys Leu Ile Asn Gly Tyr Ala Asn Ala 370 375 380

Gly Leu Phe His Lys Val Ile Ser Ser Val Gln Leu Ala Ala Lys Phe 385 390 395 400

Glu Ile Pro Glu Asn Thr Ala Phe Tyr Asn Ala Val Ile Ser Ala Cys 405 410 415

Ala Lys Ala Asp Asp Leu Ile Glu Met Glu Arg Val Tyr Ile Arg Met 420 425 430

-188 Lys Glu Arg Gln Cys Val Cys Asp Ser Arg Thr Phe Glu Ile Met Val 435 440 445

Glu Ala Tyr Glu Lys Glu Gly Met Asn Asp Lys Ile Tyr Tyr Leu Glu 450 455 460

Gln Glu Arg Gln Lys Leu Met Asp Arg Thr Val Ala Thr Lys Glu Met 465 470 475 480

Glu Asn Leu Pro Ala Gly <210> 45

<211> 2469

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(2469)

<223> <400> 45

atg gct acc gtt acc eat tEc aag ctc gtc act ccg ccg gaa tat tcc Met Ala Thr Val Thr Asn Phe Lys Leu Val Thr Pro Pro Glu Ser Ser 1 5 10 15

cgc gcc get aag cca gga get acg aag gac tcc gac goa ttc cag gag Arg Ala Asp Lys Pro Gly Ala Thr Lys Ala Ser Asp Ala Phe Gln Glu 20 25 30

aag aaa tat gtg let gtg aac tac gac cgt ggt gag cat gag gtc tag

-189 Lys Lys Ser Val Ser Val Asn Tyr Asp Arg Gly Glu His Glu Val Ser 35 40 45

gtc aac atc ggc ggg ctc agg aaa gct gat att ccg aga cgt tac cga Val Asn Ile Gly Gly Leu Arg Lys Ala Asp Ile Pro Arg Arg Tyr Arg 50 55 60

att cgg gtt gag aac gac cgg ttt cag aag gat tgg agt gta tcg gag Ile Arg Val Glu Asn Asp Arg Phe Gln Lys Asp Trp Ser Val Ser Glu 65 70 75 80

gtt gtg gac cgg ctt atg gct ctc aat cgt tgg gaa gaa gtt gat ggc Val Val Asp Arg Leu Met Ala Leu Asn Arg Trp Glu Glu Val Asp Gly 85 90 95

gtt cUt aat tcc tgg gtc ggc cgg tht gct agg aag aat ttc ccg gtt Val Leu Asn Ser Trp Val Gly Arg Phe Ala Arg Lys Asn Phe Pro Val 100 105 110

ctt atc agg gag ctt agt aga aga ggg tgt att gag ctt tgt gtg aat Leu Ile Arg Glu Leu Ser Arg Arg Gly Cys Ile Glu Leu Cys Val Asn 115 120 125

gtt ttc aag tgg aUg aag att cag aag aac tac tgt gca agg aat gat Val Phe Lys Trp Met Lys Ile Gln Lys Asn Tyr Cys Ala Arg Asn Asp 130 135 140

ata tac aat aUg atg att agg cUt cat gct agg cat aat tgg gtt gat Ile Tyr Asn Met Met Ile Arg Leu His Ala Arg His Asn Trp Val Asp 145 150 155 160

cag gat cgt ggt ctc ttc tUt gaa atg cag aaa tgg agc tgc aaa ccg Gln Ala Arg Gly Leu Phe Phe Glu Met Gln Lys Trp Ser Cys Lys Pro 165 170 175

gat gat gag acg tac gat gat ctt atc aat gac cat ggt cga gct ggt Asp Ala Glu Thr Tyr Asp Ala Leu Ile Asn Ala His Gly Arg Ala Gly 180 185 190

caa tgg cgc tgg gat aLg aat ctt atg gat gac atg tta cgt gct gct

-190 Gln Trp Arg Trp Ala Met Asn Leu Met Asp Asp Met Leu Arg Ala Ala 195 200 205

att gct cct agt cgt lea acc tac eat aac ctg ale eat gct tgt ggt Ile Ala Pro Ser Arg Ser Thr Tyr Asn Asn Leu Ile Asn Ala Cys Gly 210 215 220

tat agt gga aac tgg age gag gct ctg gaa gLa tgc aag aaa atg ace Ser Ser Gly Asn Trp Arg Glu Ala Leu Glu Val Cys Lys Lys Met Thr 225 230 235 240

get aac gga gtt gga ccg get ttg gtc act cat aac att gtg ttg lea Asp Asn Gly Val Gly Pro Asp Leu Val Thr His Asn Ile Val Leu Ser 245 250 255

gca tac aag agt ggt cgt cag tat lea aag gcg cta let tat ttt gag Ala Tyr Lys Ser Gly Arg Gln Tyr Ser Lys Ala Leu Ser Tyr Phe Glu 260 265 270

ctc atg aag gga gct aaa gtt cgt ccc get act ace act ttc eat ale Leu Met Lys Gly Ala Lys Val Arg Pro Asp Thr Thr Thr Phe Asn Ile 275 280 285

att ata tat tgt ctg lea aag ctc ggt caa agt agc caa gcc ctt get Ile Ile Tyr Cys Leu Ser Lys Leu Gly Gln Ser Ser Gln Ala Leu Asp 290 295 300

ctt ttc eat tcc aLg agg gag aag age gct gag tgc age cct get gtt Leu Phe Asn Ser Met Arg Glu Lys Arg Ala Glu Cys Arg Pro Asp Val 305 310 315 320

gtg ace ttt aeg agc ale atg cat tta tac tat gtc aag gga gag ata Val Thr Phe Thr Ser Ile Met His Leu Tyr Ser Val Lys Gly Glu Ile 325 330 335

gaa aac tgc age gcc gUg ttc gaa gca atg gtt gca gaa ggt cta aag Glu Asn Cys Arg Ala Val Phe Glu Ala Met Val Ala Glu Gly Leu Lys 340 345 350

cat eat att gtt tcc tat eat gcc tta atg ggt gcc tat gct gtt cat

-191 Pro Asn Ile Val Ser Tyr Asn Ala Leu Met Gly Ala Tyr Ala Val His 355 360 365

gga atg agt gga act gct ctc lea gtg tta gga get ale aag cag eat Gly Met Ser Gly Thr Ala Leu Ser Val Leu Gly Asp Ile Lys Gln Asn 370 375 380

ggt att ale cca get gtg gtc let tat ace tgc ttg ctc eat let tat Gly Ile Ile Pro Asp Val Val Ser Tyr Thr Cys Leu Leu Asn Ser Tyr 385 390 395 400

gga age lea cgt caa cct ggg aag gca aag gag gta ttc ctc atg aUg Gly Arg Ser Arg Gln Pro Gly Lys Ala Lys Glu Val Phe Leu Met Met 405 410 415

agg aag gaa agg age aag cca eat gtt gtt act tac eat gca ttg att Arg Lys Glu Arg Arg Lys Pro Asn Val Val Thr Tyr Asn Ala Leu Ile 420 425 430

get get tat ggg let eat ggg ttt cta gct gaa gct gtg gaa ale ttt Asp Ala Tyr Gly Ser Asn Gly Phe Leu Ala Glu Ala Val Glu Ile Phe 435 440 445

cgg cag aUg gaa caa get ggc att aag cca eat ght gtt lea gta tgc Arg Gln Met Glu Gln Asp Gly Ile Lys Pro Asn Val Val Ser Val Cys 450 455 460

act ctt ttg get gct tgt agt agg tat aaa aaa aag gUg eat gtt get Thr Leu Leu Ala Ala Cys Ser Arg Ser Lys Lys Lys Val Asn Val Asp 465 470 475 480

act gta cUt tcc gca gca cag leg age ggc att eat ctc eat acg gca Thr Val Leu Ser Ala Ala Gln Ser Arg Gly Ile Asn Leu Asn Thr Ala 485 490 495

gac tat aac lea gac att gga agc tat ata eat get goa gaa ctt gag Ala Tyr Asn Ser Ala Ile Gly Ser Tyr Ile Asn Ala Ala Glu Leu Glu 500 505 510

aag gac att gca ttg tat cag agt atg age aaa aag aaa gtc aaa gct 1584 -

-192 Lys Ala Ile Ala Leu Tyr Gln Ser Met Arg Lys Lys Lys Val Lys Ala 515 520 525

get tat gtt act ttc act ale ctt ata agc ggt lea tgt agg atg lea Asp Ser Val Thr Phe Thr Ile Leu Ile Ser Gly Ser Cys Arg Met Ser 530 535 540

aaa tac cat gaa gca att agt tac ttg aag gag atg gaa get ctc agt Lys Tyr Pro Glu Ala Ile Ser Tyr Leu Lys Glu Met Glu Asp Leu Ser 545 550 555 560

att cca ttg ace aag gag gtg tac let tag gtt cta tgt gct tac agc Ile Pro Leu Thr Lys Glu Val Tyr Ser Ser Val Leu Cys Ala Tyr Ser 565 570 575

aaa cag ggt caa gtt ace gaa gca gaa tcc ata ttc aac cag aLg aaa Lys Gln Gly Gln Val Thr Glu Ala Glu Ser Ile Phe Asn Gln Met Lys 580 585 590

atg get ggg tgc gaa cat get gtg att gca tac act lea atg ctc cat Met Ala Gly Cys Glu Pro Asp Val Ile Ala Tyr Thr Ser Met Leu His 595 600 605

get tac eat get lea gaa aag tgg gga aag gct tgt gaa ctc ttc ctg Ala Tyr Asn Ala Ser Glu Lys Trp Gly Lys Ala Cys Glu Leu Phe Leu 610 615 620

gaa atg gag goa eat gga ata gag cca get tag att get tgt lea gct Glu Met Glu Ala Asn Gly Ile Glu Pro Asp Ser Ile Ala Cys Ser Ala 625 630 635 640

* ttg atg age gct ttc aac aag gga ggt caa cag lea eat gtc ttt gtc Leu Met Arg Ala Phe Asn Lys Gly Gly Gln Pro Ser Asn Val Phe Val 645 650 655

ctg aLg get tta atg cgg gaa aaa gaa ale ccc ttc act ggt gag gtc Leu Met Asp Leu Met Arg Glu Lys Glu Ile Pro Phe Thr Gly Ala Val 660 665 670

ttc ttt gag ata tht tag get tgt aac acc ttg cag gaa tgg aaa age

-193 Phe Phe Glu Ile Phe Ser Ala Cys Asn Thr Leu Gln Glu Trp Lys Arg 675 680 685

gca ata gac ctc atc caa atg atg gat cag tac ctg cca tcg cUt tct Ala Ile Asp Leu Ile Gln Met Met Asp Pro Tyr Leu Pro Ser Leu Ser 690 695 700

atc ggg tta act aat cag aUg ctg cat ctt ttc ggg aag agt ggt aaa Ile Gly Leu Thr Asn Gln Met Leu His Leu Phe Gly Lys Ser Gly Lys 705 710 715 720

gtt gaa gca aLg atg aag ctg ttc tat aag att att gcc tct ggt gtt Val Glu Ala Met Met Lys Leu Phe Tyr Lys Ile Ile Ala Ser Gly Val 725 730 735

gga atc aac ctc aag act tat gca ata chg ttg gaa cat ctt tta gct Gly Ile Asn Leu Lys Thr Tyr Ala Ile Leu Leu Glu His Leu Leu Ala 740 745 750

gtt gga aac tgg aga aaa tac att gag gtt tta gaa tgg aUg agt ggt Val Gly Asn Trp Arg Lys Tyr Ile Glu Val Leu Glu Trp Met Ser Gly 755 760 765

gat ggt att caa ccc tag aac caa atg tat cgt gac ata atc tcc ttt Ala Gly Ile Gln Pro Ser Asn Gln Met Tyr Arg Asp Ile Ile Ser Phe 770 775 780

ggt gaa aga agt goa ggg atc gag ttc gag cat cta ata cgc caa aaa Gly Glu Arg Ser Ala Gly Ile Glu Phe Glu Pro Leu Ile Arg Gln Lys 785 790 795 800

ttg gaa tca ctg aga aac aaa gga gaa ggt ctg att cca act ttt aga Leu Glu Ser Leu Arg Asn Lys Gly Glu Gly Leu Ile Pro Thr Phe Arg 805 810 815

cac gaa ggc aca ttg ttg taa His Glu Gly Thr Leu Leu

-194 <210> 46

<211> 822

<212> PRT

<213> Arabidopsis thaliana <400> 46

Met Ala Thr Val Thr Asn Phe Lys Leu Val Thr Pro Pro Glu Ser Ser 1 5 10 15

Arg Ala Asp Lys Pro Gly Ala Thr Lys Ala Ser Asp Ala Phe Gln Glu 20 25 30

Lys Lys Ser Val Ser Val Asn Tyr Asp Arg Gly Glu His Glu Val Ser 35 40 45

Val Asn Ile Gly Gly Leu Arg Lys Ala Asp Ile Pro Arg Arg Tyr Arg 50 55 60

Ile Arg Val Glu Asn Asp Arg Phe Gln Lys Asp Trp Ser Val Ser Glu 65 70 75 80

Val Val Asp Arg Leu Met Ala Leu Asn Arg Trp Glu Glu Val Asp Gly 85 90 95

Val Leu Asn Ser Trp Val Gly Arg Phe Ala Arg Lys Asn Phe Pro Val 100 105 110

Leu Ile Arg Glu Leu Ser Arg Arg Gly Cys Ile Glu Leu Cys Val Asn 115 120 125

Val Phe Lys Trp Met Lys Ile Gln Lys Asn Tyr Cys Ala Arg Asn Asp 130 135 140

Ile Tyr Asn Met Met Ile Arg Leu His Ala Arg His Asn Trp Val Asp 145 150 155 160

-195 Gln Ala Arg Gly Leu Phe Phe Glu Met Gln Lys Trp Ser Cys Lys Pro 165 170 175

Asp Ala Glu Thr Tyr Asp Ala Leu Ile Asn Ala His Gly Arg Ala Gly 180 185 190

Gln Trp Arg Trp Ala Met Asn Leu Met Asp Asp Met Leu Arg Ala Ala 195 200 205

Ile Ala Pro Ser Arg Ser Thr Tyr Asn Asn Leu Ile Asn Ala Cys Gly 210 215 220

Ser Ser Gly Asn Trp Arg Glu Ala Leu Glu Val Cys Lys Lys Met Thr 225 230 235 240

Asp Asn Gly Val Gly Pro Asp Leu Val Thr His Asn Ile Val Leu Ser 245 250 255

Ala Tyr Lys Ser Gly Arg Gln Tyr Ser Lys Ala Leu Ser Tyr Phe Glu 260 265 270

Leu Met Lys Gly Ala Lys Val Arg Pro Asp Thr Thr Thr Phe Asn Ile 275 280 285

Ile Ile Tyr Cys Leu Ser Lys Leu Gly Gln Ser Ser Gln Ala Leu Asp 290 295 300

Leu Phe Asn Ser Met Arg Glu Lys Arg Ala Glu Cys Arg Pro Asp Val 305 310 315 320

Val Thr Phe Thr Ser Ile Met His Leu Tyr Ser Val Lys Gly Glu Ile 325 330 335

Glu Asn Cys Arg Ala Val Phe Glu Ala Met Val Ala Glu Gly Leu Lys 340 345 350

! -196 Pro Asn Ile Val Ser Tyr Asn Ala Leu Met Gly Ala Tyr Ala Val His 355 360 365

Gly Met Ser Gly Thr Ala Leu Ser Val Leu Gly Asp Ile Lys Gln Asn 370 375 380

Gly Ile Ile Pro Asp Val Val Ser Tyr Thr Cys Leu Leu Asn Ser Tyr 385 390 395 400

Gly Arg Ser Arg Gln Pro Gly Lys Ala Lys Glu Val Phe Leu Met Met 405 410 415

Arg Lys Glu Arg Arg Lys Pro Asn Val Val Thr Tyr Asn Ala Leu Ile 420 425 430

Asp Ala Tyr Gly Ser Asn Gly Phe Leu Ala Glu Ala Val Glu Ile Phe 435 440 445

Arg Gln Met Glu Gln Asp Gly Ile Lys Pro Asn Val Val Ser Val Cys 450 455 460

Thr Leu Leu Ala Ala Cys Ser Arg Ser Lys Lys Lys Val Asn Val Asp 465 470 475 480

Thr Val Leu Ser Ala Ala Gln Ser Arg Gly Ile Asn Leu Asn Thr Ala 485 490 495

Ala Tyr Asn Ser Ala Ile Gly Ser Tyr Ile Asn Ala Ala Glu Leu Glu 500 505 510

Lys Ala Ile Ala Leu Tyr Gln Ser Met Arg Lys Lys Lys Val Lys Ala 515 520 525

Asp Ser Val Thr Phe Thr Ile Leu Ile Ser Gly Ser Cys Arg Met Ser 530 535 540

Lys Tyr Pro Glu Ala Ile Ser Tyr Leu Lys Glu Met Glu Asp Leu Ser 545 550 555 560

-197 Ile Pro Leu Thr Lys Glu Val Tyr Ser Ser Val Leu Cys Ala Tyr Ser 565 570 575

Lys Gln Gly Gln Val Thr Glu Ala Glu Ser Ile Phe Asn Gln Met Lys 580 585 590

Met Ala Gly Cys Glu Pro Asp Val Ile Ala Tyr Thr Ser Met Leu His 595 600 605

Ala Tyr Asn Ala Ser Glu Lys Trp Gly Lys Ala Cys Glu Leu Phe Leu 610 615 620

Glu Met Glu Ala Asn Gly Ile Glu Pro Asp Ser Ile Ala Cys Ser Ala 625 630 635 640

Leu Met Arg Ala Phe Asn Lys Gly Gly Gln Pro Ser Asn Val Phe Val 645 650 655

Leu Met Asp Leu Met Arg Glu Lys Glu Ile Pro Phe Thr Gly Ala Val 660 665 670

Phe Phe Glu Ile Phe Ser Ala Cys Asn Thr Leu Gln Glu Trp Lys Arg 675 680 685

Ala Ile Asp Leu Ile Gln Met Met Asp Pro Tyr Leu Pro Ser Leu Ser 690 695 700

Ile Gly Leu Thr Asn Gln Met Leu His Leu Phe Gly Lys Ser Gly Lys 705 710 715 720

Val Glu Ala Met Met Lys Leu Phe Tyr Lys Ile Ile Ala Ser Gly Val 725 730 735

Gly Ile Asn Leu Lys Thr Tyr Ala Ile Leu Leu Glu His Leu Leu Ala 740 745 750

-198 Val Gly Asn Trp Arg Lys Tyr Ile Glu Val Leu Glu Trp Met Ser Gly 755 760 765

Ala Gly Ile Gln Pro Ser Asn Gln Met Tyr Arg Asp Ile Ile Ser Phe 770 775 780

Gly Glu Arg Ser Ala Gly Ile Glu Phe Glu Pro Leu Ile Arg Gln Lys 785 790 795 800

Leu Glu Ser Leu Arg Asn Lys Gly Glu Gly Leu Ile Pro Thr Phe Arg 805 810 815

His Glu Gly Thr Leu Leu <210> 47

<211> 195

<212> DNA

c213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(195)

<223> <400> 47

atg tat cUt cag tgc tat ale aac gag aag ggt gag aag gtt tac ace Met Tyr Leu Gln Cys Tyr Ile Asn Glu Lys Gly Glu Lys Val Tyr Thr 1 5 10 15

act aag aag gaa lea ccg cta ggg cta gac act gaa let gcc cat cca Thr Lys Lys Glu Ser Pro Leu Gly Leu Ala Thr Glu Ser Ala His Pro 20 25 30

-199 gcc cgg ttc tcc cat gac get aaa tac lea aag cag age gta ttg ttg Ala Arg Phe Ser Pro Asp Asp Lys Tyr Ser Lys Gln Arg Val Leu Leu 35 40 45

aag aag cga tUt ggt ctc tta ccg acc caa aac goa cct ctc cag tac Lys Lys Arg Phe Gly Leu Leu Pro Thr Gln Asn Ala Pro Leu Gln Tyr 50 55 60

tga <210> 48

<211> 64

<212> PRT

<213> Arabidopsis thaliana <400> 48

Met Tyr Leu Gln Cys Tyr Ile Asn Glu Lys Gly Glu Lys Val Tyr Thr 1 5 10 15

Thr Lys Lys Glu Ser Pro Leu Gly Leu Ala Thr Glu Ser Ala His Pro 20 25 30

Ala Arg Phe Ser Pro Asp Asp Lys Tyr Ser Lys Gln Arg Val Leu Leu 35 40 45

Lys Lys Arg Phe Gly Leu Leu Pro Thr Gln Asn Ala Pro Leu Gln Tyr 50 55 60

<210> 49

<211> 1386

<212> DNA

-200 <213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1386)

<223> <400> 49

atg aag ace ace gtt gtt tat ctg gtg att cta tgt ctc att gtt lea Met Lys Thr Thr Val Val Tyr Leu Val Ile Leu Cys Leu Ile Val Ser 1 5 10 15

tgt acc eat gga gaa acc aaa cat gta age aaa att aac tcc get gga Cys Thr Asn Gly Glu Thr Lys His Val Arg Lys Ile Asn Ser Asp Gly 20 25 30

tcc gaa get tgg gga tac gtc gaa gtt age cca aaa gca cac atg ttt Ser Glu Ala Trp Gly Tyr Val Glu Val Arg Pro Lys Ala His Met Phe 35 40 45

tgg tgg cat tat aaa agt cca tat age gtt gaa eat cat tcc aag cca Trp Trp His Tyr Lys Ser Pro Tyr Arg Val Glu Asn Pro Ser Lys Pro 50 55 60

tgg cat ale ale ctc tgg ctc caa ggt gga cat gga gct lea ggg gtt Trp Pro Ile Ile Leu Trp Leu Gln Gly Gly Pro Gly Ala Ser Gly Val 65 70 75 80

ggt ata ggg eat tUt cag gag gtt gga cca tta gac ace ttt ctc aag Gly Ile Gly Asn Phe Gln Glu Val Gly Pro Leu Asp Thr Phe Leu Lys 85 90 95

ccc age aac lea act tgg ttg aag aaa gac get ctt ttg ttt gtg get Pro Arg Asn Ser Thr Trp Leu Lys Lys Ala Asp Leu Leu Phe Val Asp 100 105 110

-201 agt cca gtt ggg gca ggg tac agt ttc gtg gag ggc aat caa aag gat Ser Pro Val Gly Ala Gly Tyr Ser Phe Val Glu Gly Asn Gln Lys Asp 115 120 125

ttg tat gtg aaa agt gat gaa gaa gca goa caa gat ttg acc aaa ctg Leu Tyr Val Lys Ser Asp Glu Glu Ala Ala Gln Asp Leu Thr Lys Leu 130 135 140

ttg caa caa ctc ttc aac aaa aac cag act tta aac caa agc cct ctc Leu Gln Gln Leu Phe Asn Lys Asn Gln Thr Leu Asn Gln Ser Pro Leu 145 150 155 160

ttc att gtt gat gaa tct tat ggt ggc aaa atc gcg gtt aag ctc ggt Phe Ile Val Ala Glu Ser Tyr Gly Gly Lys Ile Ala Val Lys Leu Gly 165 170 175

tta tcg ght att gac gca gtt caa tct ggc aaa ttg aag ctt cat ctt Leu Ser Val Ile Asp Ala Val Gln Ser Gly Lys Leu Lys Leu His Leu 180 185 190

gga gga gtg att ttg gga gat agt tgg ata tcc cct gaa gat ttt gUg Gly Gly Val Ile Leu Gly Asp Ser Trp Ile Ser Pro Glu Asp Phe Val 195 200 205

ttt tca tgg gga cat ctt ctc aag cat gtc tct agg ctt gat gac aat Phe Ser Trp Gly Pro Leu Leu Lys His Val Ser Arg Leu Asp Asp Asn 210 215 220

ggc ttg gat agc tct aat agc tta goa gag aag att aaa aca caa att Gly Leu Asp Ser Ser Asn Ser Leu Ala Glu Lys Ile Lys Thr Gln Ile 225 230 235 240

aaa aat ggt gaa tac gUt gga gcg acg caa aca tgg aLg gac ctc gaa Lys Asn Gly Glu Tyr Val Gly Ala Thr Gln Thr Trp Met Asp Leu Glu 245 250 255

aac ttg att agt tcc aaa tcc aat ttc gtc gat tEt tac aat ttt cta Asn Leu Ile Ser Ser Lys Ser Asn Phe Val Asp Phe Tyr Asn Phe Leu 260 265 270

-202 ttg gat act ggt atg gac cct gtc tcg ctc aca acg agt cta aaa atc Leu Asp Thr Gly Met Asp Pro Val Ser Leu Thr Thr Ser Leu Lys Ile 275 280 285

aaa aag gaa gag aaa ata aaa aag tat tca aga tat tta aat gat atg Lys Lys Glu Glu Lys Ile Lys Lys Tyr Ser Arg Tyr Leu Asn Asp Met 290 295 300

aga agt tta agt gac gta gaa gat gtt gaa gga gac cUt gat aaa tta Arg Ser Leu Ser Asp Val Glu Asp Val Glu Gly Asp Leu Asp Lys Leu 305 310 315 320

atg aat ggc gtt att aag aag aag ctc aag att att ccc aac gac ctc Met Asn Gly Val Ile Lys Lys Lys Leu Lys Ile Ile Pro Asn Asp Leu 325 330 335

ata tgg gga aac aat tcg gat gat gtg ttt aca gca atg gag gat gct Ile Trp Gly Asn Asn Ser Asp Asp Val Phe Thr Ala Met Glu Ala Ala 340 345 350

ttt atg aaa ccc gta att gaa gac gtc gat gag cUt ctt gac acg ggg Phe Met Lys Pro Val Ile Glu Asp Val Asp Glu Leu Leu Ala Thr Gly 355 360 365

gta gat gtg acc atc tat aat gga caa ctt gat gtt atc tgt tca aca Val Asp Val Thr Ile Tyr Asn Gly Gln Leu Asp Val Ile Cys Ser Thr 370 375 380

agt gga act gaa goa tgg gtt cac aaa ctc agg tgg gag ggg cta gaa Ser Gly Thr Glu Ala Trp Val His Lys Leu Arg Trp Glu Gly Leu Glu 385 390 395 400

gaa tEc aag aaa aUg gaa aga gag cca tta thc tgc gaa agt gac aga Glu Phe Lys Lys Met Glu Arg Glu Pro Leu Phe Cys Glu Ser Asp Arg 405 410 415

gca aca aga ggc tEt acc aaa tca tac aaa aat ctc cat ttt tat tgg Ala Thr Arg Gly Phe Thr Lys Ser Tyr Lys Asn Leu His Phe Tyr Trp 420 425 430

-203 att ctt ggt gct ggt cat ttt gta cca gta get gag cca tgt gta gca Ile Leu Gly Ala Gly His Phe Val Pro Val Asp Glu Pro Cys Val Ala 435 440 445

tta aaa atg gtt gga gag ata acc aag lea cca caa ctt tga Leu Lys Met Val Gly Glu Ile Thr Lys Ser Pro Gln Leu 450 455 460

<210> 50

<211> 461

<212> PRT

<213> Arabidopsis thaliana <400> 50

Met Lys Thr Thr Val Val Tyr Leu Val Ile Leu Cys Leu Ile Val Ser 1 5 10 15

Cys Thr Asn Gly Glu Thr Lys His Val Arg Lys Ile Asn Ser Asp Gly 20 25 30

Ser Glu Ala Trp Gly Tyr Val Glu Val Arg Pro Lys Ala His Met Phe 35 40 45

Trp Trp His Tyr Lys Ser Pro Tyr Arg Val Glu Asn Pro Ser Lys Pro 50 55 60

Trp Pro Ile Ile Leu Trp Leu Gln Gly Gly Pro Gly Ala Ser Gly Val 65 70 75 80

Gly Ile Gly Asn Phe Gln Glu Val Gly Pro Leu Asp Thr Phe Leu Lys 85 90 95

Pro Arg Asn Ser Thr Trp Leu Lys Lys Ala Asp Leu Leu Phe Val Asp 100 105 110

-204 Ser Pro Val Gly Ala Gly Tyr Ser Phe Val Glu Gly Asn Gln Lys Asp 115 120 125

Leu Tyr Val Lys Ser Asp Glu Glu Ala Ala Gln Asp Leu Thr Lys Leu 130 135 140

Leu Gln Gln Leu Phe Asn Lys Asn Gln Thr Leu Asn Gln Ser Pro Leu 145 150 155 160

Phe Ile Val Ala Glu Ser Tyr Gly Gly Lys Ile Ala Val Lys Leu Gly 165 170 175

Leu Ser Val Ile Asp Ala Val Gln Ser Gly Lys Leu Lys Leu His Leu 180 185 190

Gly Gly Val Ile Leu Gly Asp Ser Trp Ile Ser Pro Glu Asp Phe Val 195 200 205

Phe Ser Trp Gly Pro Leu Leu Lys His Val Ser Arg Leu Asp Asp Asn 210 215 220

Gly Leu Asp Ser Ser Asn Ser Leu Ala Glu Lys Ile Lys Thr Gln Ile 225 230 235 240

Lys Asn Gly Glu Tyr Val Gly Ala Thr Gln Thr Trp Met Asp Leu Glu 245 250 255

Asn Leu Ile Ser Ser Lys Ser Asn Phe Val Asp Phe Tyr Asn Phe Leu 260 265 270

Leu Asp Thr Gly Met Asp Pro Val Ser Leu Thr Thr Ser Leu Lys Ile 275 280 285

Lys Lys Glu Glu Lys Ile Lys Lys Tyr Ser Arg Tyr Leu Asn Asp Met 290 295 300

Arg Ser Leu Ser Asp Val Glu Asp Val Glu Gly Asp Leu Asp Lys Leu

-205 305 310 315 320

Met Asn Gly Val Ile Lys Lys Lys Leu Lys Ile Ile Pro Asn Asp Leu 325 330 335

Ile Trp Gly Asn Asn Ser Asp Asp Val Phe Thr Ala Met Glu Ala Ala Phe Met Lys Pro Val Ile Glu Asp Val Asp Glu Leu Leu Ala Thr Gly 355 360 365

Val Asp Val Thr Ile Tyr Asn Gly Gln Leu Asp Val Ile Cys Ser Thr Ser Gly Thr Glu Ala Trp Val His Lys Leu Arg Trp Glu Gly Leu Glu Glu Phe Lys Lys Met Glu Arg Glu Pro Leu Phe Cys Glu Ser Asp Arg Ala Thr Arg Gly Phe Thr Lys Ser Tyr Lys Asn Leu His Phe Tyr Trp Ile Leu Gly Ala Gly His Phe Val Pro Val Asp Glu Pro Cys Val Ala Leu Lys Met Val Gly Glu Ile Thr Lys Ser Pro Gln Leu 450 455 460

<210> 51

<211> 2775

<212> DNA

<213> Arabidopsis thaliana

-206 <220> <221> CDS

<222> (1)..(2775)

<223> <400> 51

atg gcg gag gta leg atg gga agc agc agt agc agc acg get ctg let Met Ala Glu Val Ser Met Gly Ser Ser Ser Ser Ser Thr Asp Leu Ser 1 5 10 15

ccc gag gaa gag cga gtt tUc ale age gac att gct att gct gct gag Pro Glu Glu Glu Arg Val Phe Ile Arg Asp Ile Ala Ile Ala Ala Glu 20 25 30

get eat agt aaa gaa ggc get ace tUt tat ctc ale act cag age tgg Ala Asn Ser Lys Glu Gly Asp Thr Phe Tyr Leu Ile Thr Gln Arg Trp 35 40 45

tgg caa gaa tgg att gag tat gtg eat caa gac caa cca tgt aac ace Trp Gln Glu Trp Ile Glu Tyr Val Asn Gln Asp Gln Pro Cys Asn Thr 50 55 60

eat get ggg let lea ctg lea gag cat tgc gac let cct ggt lea agc Asn Asp Gly Ser Ser Leu Ser Glu His Cys Asp Ser Pro Gly Ser Ser 65 70 75 80

act cta aag aag cat let agg att get aac let get ttg ale tat get Thr Leu Lys Lys Pro Ser Arg Ile Asp Asn Ser Asp Leu Ile Tyr Asp 85 90 95

let tag ctg gag gac ccg agt eat acc agt gag att att gaa ace ctt Ser Ser Leu Glu Asp Pro Ser Asn Thr Ser Glu Ile Ile Glu Thr Leu 100 105 110

cag gaa ggt cgt get tat gtt ttg ctc cct caa gaa gUg tgg aac caa Gln Glu Gly Arg Asp Tyr Val Leu Leu Pro Gln Glu Val Trp Asn Gln 115 120 125 -207 ttg cgt lea tgg tac ggg ggt ggt cca act ctg gca cgg age gtc att Leu

Arg Ser Trp Tyr Gly Gly Gly Pro Thr Leu Ala Arg Arg Val Ile 130 135 140

agc lea ggt ctc let caa ace gaa ttg gct gta gag gtt tac cct tta Ser Ser Gly Leu Ser Gln Thr Glu Leu Ala Val Glu Val Tyr Pro Leu 145 150 155 160

cgt ctt cag cta ctt ctg atg cca aaa agt gac cat agt gcc ata age Arg Leu Gln Leu Leu Leu Met Pro Lys Ser Asp His Ser Ala Ile Arg 165 170 175

att agc aaa aag gaa act ale age gag ctc cat cga age gcc tgt gaa Ile Ser Lys Lys Glu Thr Ile Arg Glu Leu His Arg Arg Ala Cys Glu 180 185 190

att ttt gac ctc gac lea gag cat gta cgc att tgg get tac tac ggc Ile Phe Asp Leu Asp Ser Glu His Val Arg Ile Trp Asp Tyr Tyr Gly 195 200 205

cac caa aag tat let ttg atg eat gac tta get aag ace ctg gac get His Gln Lys Tyr Ser Leu Met Asn Asp Leu Asp Lys Thr Leu Asp Asp 210 215 220

gct aac cta caa aLg get cag get att ttg gtg gag gUg cht gac ale Ala Asn Leu Gln Met Asp Gln Asp Ile Leu Val Glu Val Leu Asp Ile 225 230 235 240

eat ggt ace tta lea agt gct cac att caa let gct caa gag aac gga Asn Gly Thr Leu Ser Ser Ala His Ile Gln Ser Ala Gln Glu Asn Gly 245 250 255

ttg gtg get gga gac let act let att ctc att gag cct let aaa leg Leu Val Asp Gly Asp Ser Thr Ser Ile Leu Ile Glu Pro Ser Lys Ser 260 265 270

agc ttg gct gcc goa gga ggg ttc tat lea agc agg eat gca ttc age Ser Leu Ala Ala Ala Gly Gly Phe Ser Ser Ser Arg Asn Ala Phe Arg 275 280 285

-208 act ggt agt gta gaa gtt lea caa let ttt get aac ace tac agt agc Thr Gly Ser Val Glu Val Ser Gln Ser Phe Asp Asn Thr Tyr Ser Ser 290 295 300

act ggc gtc acc act agg gga tcc ace gct ggc ttg ace ggg ctg cta Thr Gly Val Thr Thr Arg Gly Ser Thr Ala Gly Leu Thr Gly Leu Leu 305 310 315 320

eat ctt ggg eat act tgt ttc atg eat agt gcg att cag tgt ctg gtt Asn Leu Gly Asn Thr Cys Phe Met Asn Ser Ala Ile Gln Cys Leu Val 325 330 335

cat ace cct gag ttt gct agt tac tUt caa gaa get tat cat caa gaa His Thr Pro Glu Phe Ala Ser Tyr Phe Gln Glu Asp Tyr His Gln Glu 340 345 350

ata eat tgg caa aac cct ctt gga atg gtg ggg gaa tta get ctc gca Ile Asn Trp Gln Asn Pro Leu Gly Met Val Gly Glu Leu Ala Leu Ala 355 360 365

ttt ggt gac ttg ctc agg aag tta tgg get cct ggg cgg ace cca att Phe Gly Asp Leu Leu Arg Lys Leu Trp Ala Pro Gly Arg Thr Pro Ile 370 375 380

gca cct cgt cca tUc aaa gct aaa ctt gct cgc ttt get cct caa ttt 1200 '

Ala Pro Arg Pro Phe Lys Ala Lys Leu Ala Arg Phe Ala Pro Gln Phe 385 390 395 400

agt ggg tac eat caa cat get leg cag gag ctt tta gag ttt ctg ctg Ser Gly Tyr Asn Gln His Asp Ser Gln Glu Leu Leu Ala Phe Leu Leu 405 410 415

get ggt cEt cac gag gac cta eat cgt gtt aaa cac aaa cca tat ata Asp Gly Leu His Glu Asp Leu Asn Arg Val Lys His Lys Pro Tyr Ile 420 425 430

eat tat cga gac gca get ggg cgc cct get gaa gaa ght get get gag Asn Ser Arg Asp Ala Asp Gly Arg Pro Asp Glu Glu Val Ala Asp Glu 435 440 445

-209 ttc tgg aaa aat cat att gct cgt aat gac tca ata ata gtt gat gtt Phe Trp Lys Asn His Ile Ala Arg Asn Asp Ser Ile Ile Val Asp Val 450 455 460

tgt cag ggc caa tat aag tca aca ttg gtg tgt cca atc tgc aac aag Cys Gln Gly Gln Tyr Lys Ser Thr Leu Val Cys Pro Ile Cys Asn Lys 465 470 475 480

gtt tct gta acg ttt gat ccc ttc aLg tac ctg tct ttg ccg ctg cag Val Ser Val Thr Phe Asp Pro Phe Met Tyr Leu Ser Leu Pro Leu Gln 485 490 495

ttc aac aca aca cga gca ata aca gtc aca gtt ttt tct tgt gat aaa Phe Asn Thr Thr Arg Ala Ile Thr Val Thr Val Phe Ser Cys Asp Lys 500 505 510

act gcc tta cct tcc act atc aca gtc aat ght tca aag cag gga cgt Thr Ala Leu Pro Ser Thr Ile Thr Val Asn Val Ser Lys Gln Gly Arg 515 520 525

tgc aga gac ttg atc cag gca tta aca aat gat tgt tcc ttg aag caa Cys Arg Asp Leu Ile Gln Ala Leu Thr Asn Ala Cys Ser Leu Lys Gln 530 535 540

agt gaa gag ctg aaa cUt goa gag att cgg aat aat ttt atc cat aga Ser Glu Glu Leu Lys Leu Ala Glu Ile Arg Asn Asn Phe Ile His Arg 545 550 555 560

tta ttt gaa gac cat tta att cag ttg tca agt atc aaa gat gat gac Leu Phe Glu Asp Pro Leu Ile Pro Leu Ser Ser Ile Lys Asp Asp Asp 565 570 575

cac ctt gat gca tac aaa ctt tca aag tat tcg gag aat acg act ttg His Leu Ala Ala Tyr Lys Leu Ser Lys Ser Ser Glu Asn Thr Thr Leu 580 585 590

ctt aga cta gLa ctc cgc cgc aga gat cag aaa gat ggg gaa cgt gaa Leu Arg Leu Val Leu Arg Arg Arg Asp Gln Lys Ala Gly Glu Arg Glu 595 600 605

-210 agt ace gta caa ttg aaa ccc tgt gga ace cct ctt ctc lea lea gct Ser Thr Val Gln Leu Lys Pro Cys Gly Thr Pro Leu Leu Ser Ser Ala 610 615 620

lea tgc gga get gca ctc acc aaa gga aaa ale cat tgc ctc gtc cag Ser Cys Gly Asp Ala Leu Thr Lys Gly Lys Ile His Cys Leu Val Gln 625 630 635 640

eat atg ctt lea cct ttt cgg agg gaa gaa let gtg ggc aaa aaa gga Asn Met Leu Ser Pro Phe Arg Arg Glu Glu Ser Val Gly Lys Lys Gly 645 650 655

eat let get let agc ale ccc gag age agg lea gct cga ttt eat eat Asn Ser Asp Ser Ser Ile Pro Glu Arg Arg Ser Ala Arg Phe Asn Asn 660 665 670

act gag gaa gaa get aaa gUt ggt gga ctg aaa aaa gcc aag aaa agc Thr Glu Glu Glu Asp Lys Val Gly Gly Leu Lys Lys Ala Lys Lys Ser 675 680 685

aac tcc tcc gac ttg ggt get let aaa tta tcc ctg caa ctc att get Asn Ser Ser Asp Leu Gly Ala Ser Lys Leu Ser Leu Gln Leu Ile Asp 690 695 700

gaa gac aac aaa acg att eat ctg cca gac eat gaa goa gaa gct atg Glu Asp Asn Lys Thr Ile Asn Leu Pro Asp Asn Glu Ala Glu Ala Met 705 710 715 720

aaa tta cag lea lea gct act gta act ata tat ttg get tgg ace cca Lys Leu Pro Ser Ser Ala Thr Val Thr Ile Tyr Leu Asp Trp Thr Pro 725 730 735

gaa ctc let ggt atg tat get ata act tgc ctg gag agt ttg cat gaa Glu Leu Ser Gly Met Tyr Asp Ile Thr Cys Leu Glu Ser Leu Pro Glu 740 745 750

gta ctc aaa tat gga cct act acc aag aag get cgt lea gaa cat ctt Val Leu Lys Tyr Gly Pro Thr Thr Lys Lys Ala Arg Ser Glu Pro Leu 755 760 765

-211 tat tta tat gca tgt ttg gaa gcg ttt cta cgc gaa gag cct ttg gta Ser Leu Tyr Ala Cys Leu Glu Ala Phe Leu Arg Glu Glu Pro Leu Val 770 775 780

cct gac gaa atg tgg ttc tgt cca caa tgc eat gaa age agg cag gca Pro Asp Glu Met Trp Phe Cys Pro Gln Cys Asn Glu Arg Arg Gln Ala 785 790 795 800

agc aaa aag ctt get ctg tgg agg ctt cct gag gtc tta gtc ata cat Ser Lys Lys Leu Asp Leu Trp Arg Leu Pro Glu Val Leu Val Ile His 805 810 815

cta aag age ttc lea tac agc agg tcc atg aag cat aag ttg gaa ace Leu Lys Arg Phe Ser Tyr Ser Arg Ser Met Lys His Lys Leu Glu Thr 820 825 830

ttt gtt aac ttt ccc att cat gac tta get cta ace aag tat gLa gcc Phe Val Asn Phe Pro Ile His Asp Leu Asp Leu Thr Lys Tyr Val Ala 835 840 845

aac aaa aac cta let caa cct caa cta tat gag ctc tat gac ttg acc Asn Lys Asn Leu Ser Gln Pro Gln Leu Tyr Glu Leu Tyr Ala Leu Thr 850 855 860

aac cat tat ggt ggt atg ggc agc gga cac tac act goa cat ale aag Asn His Tyr Gly Gly Met Gly Ser Gly His Tyr Thr Ala His Ile Lys 865 870 875 880

ctt ttg gac gac agt agg tgg tat aac ttc get get agc cat ata lea Leu Leu Asp Asp Ser Arg Trp Tyr Asn Phe Asp Asp Ser His Ile Ser 885 890 895

cac ata aac gaa get get gtg aag lea ggt gct gca tat gtg ctc tUc His Ile Asn Glu Asp Asp Val Lys Ser Gly Ala Ala Tyr Val Leu Phe 900 905 910

tac agg agg aag let get gca ggc gga aaa aLg ace tea Tyr Arg Arg Lys Ser Asp Ala Gly Gly Lys Met Thr 915 920

-212 <210> 52

<211> 924

<212> PRT

<213> Arabidopsis thaliana <400> 52

Met Ala Glu Val Ser Met Gly Ser Ser Ser Ser Ser Thr Asp Leu Ser 1 5 10 15

Pro Glu Glu Glu Arg Val Phe Ile Arg Asp Ile Ala Ile Ala Ala Glu 20 25 30

Ala Asn Ser Lys Glu Gly Asp Thr Phe Tyr Leu Ile Thr Gln Arg Trp 35 40 45

Trp Gln Glu Trp Ile Glu Tyr Val Asn Gln Asp Gln Pro Cys Asn Thr Asn Asp Gly Ser Ser Leu Ser Glu His Cys Asp Ser Pro Gly Ser Ser 65 70 75 80

Thr Leu Lys Lys Pro Ser Arg Ile Asp Asn Ser Asp Leu Ile Tyr Asp Ser Ser Leu Glu Asp Pro Ser Asn Thr Ser Glu Ile Ile Glu Thr Leu 100 105 110

Gln Glu Gly Arg Asp Tyr Val Leu Leu Pro Gln Glu Val Trp Asn Gln 115 120 125

Leu Arg Ser Trp Tyr Gly Gly Gly Pro Thr Leu Ala Arg Arg Val Ile

-213 Ser Ser Gly Leu Ser Gln Thr Glu Leu Ala Val Glu Val Tyr Pro Leu 145 150 155 160

Arg Leu Gln Leu Leu Leu Met Pro Lys Ser Asp His Ser Ala Ile Arg 165 170 175

Ile Ser Lys Lys Glu Thr Ile Arg Glu Leu His Arg Arg Ala Cys Glu 180 185 190

Ile Phe Asp Leu Asp Ser Glu His Val Arg Ile Trp Asp Tyr Tyr Gly 195 200 205

His Gln Lys Tyr Ser Leu Met Asn Asp Leu Asp Lys Thr Leu Asp Asp 210 215 220

Ala Asn Leu Gln Met Asp Gln Asp Ile Leu Val Glu Val Leu Asp Ile 225 230 235 240

Asn Gly Thr Leu Ser Ser Ala His Ile Gln Ser Ala Gln Glu Asn Gly 245 250 255

Leu Val Asp Gly Asp Ser Thr Ser Ile Leu Ile Glu Pro Ser Lys Ser 260 265 270

Ser Leu Ala Ala Ala Gly Gly Phe Ser Ser Ser Arg Asn Ala Phe Arg 275 280 285

Thr Gly Ser Val Glu Val Ser Gln Ser Phe Asp Asn Thr Tyr Ser Ser 290 295 300

Thr Gly Val Thr Thr Arg Gly Ser Thr Ala Gly Leu Thr Gly Leu Leu 305 310 315 320

Asn Leu Gly Asn Thr Cys Phe Met Asn Ser Ala Ile Gln Cys Leu Val 325 330 335

His Thr Pro Glu Phe Ala Ser Tyr Phe Gln Glu Asp Tyr His Gln Glu 340 345 350

-214 Ile Asn Trp Gln Asn Pro Leu Gly Met Val Gly Glu Leu Ala Leu Ala 355 360 365

Phe Gly Asp Leu Leu Arg Lys Leu Trp Ala Pro Gly Arg Thr Pro Ile 370 375 380

Ala Pro Arg Pro Phe Lys Ala Lys Leu Ala Arg Phe Ala Pro Gln Phe 385 390 395 400

Ser Gly Tyr Asn Gln His Asp Ser Gln Glu Leu Leu Ala Phe Leu Leu 405 410 415

Asp Gly Leu His Glu Asp Leu Asn Arg Val Lys His Lys Pro Tyr Ile 420 425 430

Asn Ser Arg Asp Ala Asp Gly Arg Pro Asp Glu Glu Val Ala Asp Glu 435 440 445

Phe Trp Lys Asn His Ile Ala Arg Asn Asp Ser Ile Ile Val Asp Val 450 455 460

* Cys Gln Gly Gln Tyr Lys Ser Thr Leu Val Cys Pro Ile Cys Asn Lys 465 470 475 480

Val Ser Val Thr Phe Asp Pro Phe Met Tyr Leu Ser Leu Pro Leu Gln 485 490 495

Phe Asn Thr Thr Arg Ala Ile Thr Val Thr Val Phe Ser Cys Asp Lys 500 505 510

Thr Ala Leu Pro Ser Thr Ile Thr Val Asn Val Ser Lys Gln Gly Arg 515 520 525

Cys Arg Asp Leu Ile Gln Ala Leu Thr Asn Ala Cys Ser Leu Lys Gln 530 535 540

-215 Ser Glu Glu Leu Lys Leu Ala Glu Ile Arg Asn Asn Phe Ile His Arg Leu Phe Glu Asp Pro Leu Ile Pro Leu Ser Ser Ile Lys Asp Asp Asp His Leu Ala Ala Tyr Lys Leu Ser Lys Ser Ser Glu Asn Thr Thr Leu Leu Arg Leu Val Leu Arg Arg Arg Asp Gln Lys Ala Gly Glu Arg Glu Ser Thr Val Gln Leu Lys Pro Cys Gly Thr Pro Leu Leu Ser Ser Ala Ser Cys Gly Asp Ala Leu Thr Lys Gly Lys Ile His Cys Leu Val Gln Asn Met Leu Ser Pro Phe Arg Arg Glu Glu Ser Val Gly Lys Lys Gly Asn Ser Asp Ser Ser Ile Pro Glu Arg Arg Ser Ala Arg Phe Asn As Thr Glu Glu Glu Asp Lys Val Gly Gly Leu Lys Lys Ala Lys Lys Ser 675 680 685

Asn Ser Ser Asp Leu Gly Ala Ser Lys Leu Ser Leu Gln Leu Ile Asp Glu Asp Asn Lys Thr Ile Asn Leu Pro Asp Asn Glu Ala Glu Ala Met Lys Leu Pro Ser Ser Ala Thr Val Thr Ile Tyr Leu Asp Trp Thr Pro Glu Leu Ser Gly Met Tyr Asp Ile Thr Cys Leu Glu Ser Leu Pro

-216 Val Leu Lys Tyr Gly Pro Thr Thr Lys Lys Ala Arg Ser Glu Pro Leu 755 760 765

Ser Leu Tyr Ala Cys Leu Glu Ala Phe Leu Arg Glu Glu Pro Leu Val 770 775 780

Pro Asp Glu Met Trp Phe Cys Pro Gln Cys Asn Glu Arg Arg Gln Ala 785 790 795 800

Ser Lys Lys Leu Asp Leu Trp Arg Leu Pro Glu Val Leu Val Ile His 805 810 815

Leu Lys Arg Phe Ser Tyr Ser Arg Ser Met Lys His Lys Leu Glu Thr 820 825 830

Phe Val Asn Phe Pro Ile His Asp Leu Asp Leu Thr Lys Tyr Val Ala 835 840 845

Asn Lys Asn Leu Ser Gln Pro Gln Leu Tyr Glu Leu Tyr Ala Leu Thr 850 855 860

Asn His Tyr Gly Gly Met Gly Ser Gly His Tyr Thr Ala His Ile Lys 865 870 875 880

Leu Leu Asp Asp Ser Arg Trp Tyr Asn Phe Asp Asp Ser His Ile Ser 885 890 895

His Ile Asn Glu Asp Asp Val Lys Ser Gly Ala Ala Tyr Val Leu Phe 900 905 910

Tyr Arg Arg Lys Ser Asp Ala Gly Gly Lys Met Thr 915 920

<210> 53

<211> 840

-217 <212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(840)

<223> <400> 53

atg gcg gtc tag ttt eat ace acg ctt cac cag cct let ctg agt ccg Met Ala Val Ser Phe Asn Thr Thr Leu His Gln Pro Ser Leu Ser Pro 1 5 10 15

agc tgt agc ale aag cUt tat let ggg tta aag cct caa let goa agc Ser Cys Ser Ile Lys Leu Tyr Ser Gly Leu Lys Pro Gln Ser Ala Ser 20 25 30

ttt ttg gca agt ggg tat cag eat ttg aac aag gag ttc tat gga age Phe Leu Ala Ser Gly Tyr Gln Asn Leu Asn Lys Glu Phe Tyr Gly Arg 35 40 45

gtt tat aag agt ctg caa let ggg act ggg aaa gcg agc agg lea cgg Val Tyr Lys Ser Leu Gln Ser Gly Thr Gly Lys Ala Ser Arg Ser Arg 50 55 60

gta aag aLg atg cca ata gga ace cag age gLa ccc tac age aac cga Val Lys Met Met Pro Ile Gly Thr Pro Arg Val Pro Tyr Arg Asn Arg 65 70 75 80

gaa gaa ggg act tgg caa tgg gtt get ata tgg eat gcc ctt tat cga Glu Glu Gly Thr Trp Gln Trp Val Asp Ile Trp Asn Ala Leu Tyr Arg 85 90 95

gag cgt gta ale tEc att gga caa aac att get gaa gag ttt agc aac Glu Arg Val Ile Phe Ile Gly Gln Asn Ile Asp Glu Glu Phe Ser Asn

-218 100 105 110

cag ata tta gca acc aLg ttg tac ctt get act ctt get gac leg agg Gln Ile Leu Ala Thr Met Leu Tyr Leu Asp Thr Leu Asp Asp Ser Arg 115 120 125

agg att tat atg tac cta eat ggt ccg ggt ggt get ctt act cca agt Arg Ile Tyr Met Tyr Leu Asn Gly Pro Gly Gly Asp Leu Thr Pro Ser 130 135 140

cta gac ale tat get ace atg aag agc ttg aaa agt ccg gtt ggg ace Leu Ala Ile Tyr Asp Thr Met Lys Ser Leu Lys Ser Pro Val Gly Thr 145 150 155 160

cat tgc gtt ggg ctt gct tac aac ctt gca ggt ttt ctt ctt gag gct His Cys Val Gly Leu Ala Tyr Asn Leu Ala Gly Phe Leu Leu Ala Ala 165 170 175

gga gaa aag ggt cac cga ttt gcg atg cca tta lea age ale gcc ctc Gly Glu Lys Gly His Arg Phe Ala Met Pro Leu Ser Arg Ile Ala Leu 180 185 190

cag lea cca get ggt gca gcc cgt ggt cag gct get get ale caa eat Gln Ser Pro Ala Gly Ala Ala Arg Gly Gln Ala Asp Asp Ile Gln Asn 195 200 205

gaa gca aaa gag cht lea agg ata age gac tac ctc ttc eat gaa cta Glu Ala Lys Glu Leu Ser Arg Ile Arg Asp Tyr Leu Phe Asn Glu Leu 210 215 220

gac aag eat ace ggc cag cat gcg gaa agg gtc tCc aaa gac ttg agc Ala Lys Asn Thr Gly Gln Pro Ala Glu Arg Val Phe Lys Asp Leu Ser 225 230 235 240

cgg gtg aaa agg ttc eat gca gag gaa gca ale gag tat gga ctt att Arg Val Lys Arg Phe Asn Ala Glu Glu Ala Ile Glu Tyr Gly Leu Ile 245 250 255

get aag att gtt age cca ccg cgc ale aaa gaa gac gct cat cgc caa Asp Lys Ile Val Arg Pro Pro Arg Ile Lys Glu Asp Ala Pro Arg Gln

-219 260 265 270

gac gaa agc gca ggg cta ggc tag Asp Glu Ser Ala Gly Leu Gly <210> 54

<211> 279

<212> PRT

<213> Arabidopsis thaliana <400> 54

Met Ala Val Ser Phe Asn Thr Thr Leu His Gln Pro Ser Leu Ser Pro Ser Cys Ser Ile Lys Leu Tyr Ser Gly Leu Lys Pro Gln Ser Ala Ser Phe Leu Ala Ser Gly Tyr Gln Asn Leu Asn Lys Glu Phe Tyr Gly Arg Val Tyr Lys Ser Leu Gln Ser Gly Thr Gly Lys Ala Ser Arg Ser Arg Val Lys Met Met Pro Ile Gly Thr Pro Arg Val Pro Tyr Arg Asn Arg Glu Glu Gly Thr Trp Gln Trp Val Asp Ile Trp Asn Ala Leu Tyr Arg Glu Arg Val Ile Phe Ile Gly Gln Asn Ile Asp Glu Glu Phe Ser Asn Gln Ile Leu Ala Thr Met Leu Tyr Leu Asp Thr Leu Asp Asp Ser Arg 115 120 125

-220 Arg Ile Tyr Met Tyr Leu Asn Gly Pro Gly Gly Asp Leu Thr Pro Ser 130 135 140

Leu Ala Ile Tyr Asp Thr Met Lys Ser Leu Lys Ser Pro Val Gly Thr 145 150 155 160

His Cys Val Gly Leu Ala Tyr Asn Leu Ala Gly Phe Leu Leu Ala Ala 165 170 175

Gly Glu Lys Gly His Arg Phe Ala Met Pro Leu Ser Arg Ile Ala Leu 180 185 190

Gln Ser Pro Ala Gly Ala Ala Arg Gly Gln Ala Asp Asp Ile Gln Asn 195 200 205

Glu Ala Lys Glu Leu Ser Arg Ile Arg Asp Tyr Leu Phe Asn Glu Leu 210 215 220

Ala Lys Asn Thr Gly Gln Pro Ala Glu Arg Val Phe Lys Asp Leu Ser 225 230 235 240

Arg Val Lys Arg Phe Asn Ala Glu Glu Ala Ile Glu Tyr Gly Leu Ile 245 250 255

Asp Lys Ile Val Arg Pro Pro Arg Ile Lys Glu Asp Ala Pro Arg Gln 260 265 270

Asp Glu Ser Ala Gly Leu Gly <210> 55

<211> 3135

<212> DNA

<213> Arabidopsis thaliana

-221 <220> <221> CDS

<222> (1)..(3135)

<223> <400> 55

atg gcg agc eat get ttg aag act tgg gtt tag get aag ctg atg atg Met Ala Ser Asn Asp Leu Lys Thr Trp Val Ser Asp Lys Leu Met Met 1 5 10 15

cta ctt ggc tac let caa gcg get gtt gUt aac tat ctc att gca atg Leu Leu Gly Tyr Ser Gln Ala Ala Val Val Asn Tyr Leu Ile Ala Met 20 25 30

get aaa aaa ace aaa lea cca act gaa ctt gtg gga gag ttg gtg get Ala Lys Lys Thr Lys Ser Pro Thr Glu Leu Val Gly Glu Leu Val Asp 35 40 45

tac ggg ttt tag let let ggt get act cgt leg ttt goa gaa gaa att Tyr Gly Phe Ser Ser Ser Gly Asp Thr Arg Ser Phe Ala Glu Glu Ile 50 55 60

tUt gcc age gtt ccc cgt aaa act get ggt gLa eat ctc tac caa aaa Phe Ala Arg Val Pro Arg Lys Thr Ala Gly Val Asn Leu Tyr Gln Lys 65 70 75 80

cat gaa gca gag goa gca atg cta gtg agg aag cag aaa ace tat get Hls Glu Ala Glu Ala Ala Met Leu Val Arg Lys Gln Lys Thr Tyr Ala 85 90 95

ctt tta get get get get get gaa gac gaa gtt gtt gUg gag aaa aaa Leu Leu Asp Ala Asp Asp Asp Glu Asp Glu Val Val Val Glu Lys Lys 100 105 110

tat lea gtt tat gaa let age aaa lea get aag ggc aag aaa agg ttt

-222 Ser Ser Val Ser Glu Ser Arg Lys Ser Asp Lys Gly Lys Lys Arg Phe 115 120 125

aga aag aaa agt ggg cag tca gat gaa agt gat ggc gag gtg gcc gtt Arg Lys Lys Ser Gly Gln Ser Asp Glu Ser Asp Gly Glu Val Ala Val 130 135 140

aga gag gat agt aga cac gUt aga aga aag gtt tct gaa gag gat gat Arg Glu Asp Ser Arg His Val Arg Arg Lys Val Ser Glu Glu Asp Asp 145 150 155 160

ggt tat gag tca gaa gag gaa aga gtg cgt gac caa aag gag aga gaa Gly Ser Glu Ser Glu Glu Glu Arg Val Arg Asp Gln Lys Glu Arg Glu 165 170 175

gaa ctg gag cag cat tta aaa gat cgt gat act gca cgg aca cga aag Glu Leu Glu Gln His Leu Lys Asp Arg Asp Thr Ala Arg Thr Arg Lys 180 185 190

cta aca gag caa acg ttg tca aag aaa gag aaa gaa gag gct gtt cga Leu Thr Glu Gln Thr Leu Ser Lys Lys Glu Lys Glu Glu Ala Val Arg 195 200 205

aga goa aat gct ttg gag aag gat gat tta tat tcc tta agg aaa gtc Arg Ala Asn Ala Leu Glu Lys Asp Asp Leu Tyr Ser Leu Arg Lys Val 210 215 220

tcg aga caa gaa tac tta aag aag aga gaa caa aag aaa ctg gat gaa Ser Arg Gln Glu Tyr Leu Lys Lys Arg Glu Gln Lys Lys Leu Asp Glu 225 230 235 240

cta agg gat gag ata gaa gat gaa caa tat ctt tEc gga ggt gaa aag Leu Arg Asp Glu Ile Glu Asp Glu Gln Tyr Leu Phe Gly Gly Glu Lys 245 250 255

ctc aca gaa acg gag ctt cgt gag tht agg tac aag aaa gag ctt tat Leu Thr Glu Thr Glu Leu Arg Glu Phe Arg Tyr Lys Lys Glu Leu Tyr 260 265 270

gac ctc gtg aag aaa aga aca caa gat gaa gat aac gtc gag gag tat

-223 Asp Leu Val Lys Lys Arg Thr Gln Asp Glu Asp Asn Val Glu Glu Tyr 275 280 285

age att cca get gct tat get caa gag gga ggt gtt get cag gag aag Arg Ile Pro Asp Ala Tyr Asp Gln Glu Gly Gly Val Asp Gln Glu Lys 290 295 300

agg ttt let gtt get gEt caa cga tac agg gac ctg get lea ace gag Arg Phe Ser Val Ala Val Gln Arg Tyr Arg Asp Leu Asp Ser Thr Glu 305 310 315 320

aaa atg eat cca ttc gca gag caa gaa gct tgg gag gac cat cag att Lys Met Asn Pro Phe Ala Glu Gln Glu Ala Trp Glu Asp His Gln Ile 325 330 335

gga aaa gca ace tta aaa ttt ggt gca aag eat aag caa gcc lea gac Gly Lys Ala Thr Leu Lys Phe Gly Ala Lys Asn Lys Gln Ala Ser Asp 340 345 350

get tat cag ttt gtg ttt gaa gac caa ata aac thc ata aag gaa let Asp Tyr Gln Phe Val Phe Glu Asp Gln Ile Asn Phe Ile Lys Glu Ser 355 360 365

gtc atg gct ggt gaa eat tat gaa get get atg get gca aaa caa aaa Val Met Ala Gly Glu Asn Tyr Glu Asp Ala Met Asp Ala Lys Gln Lys 370 375 380

tat caa get ttg gca gag aaa ace gct tta gag gaa ctt cag gaa gtc Ser Gln Asp Leu Ala Glu Lys Thr Ala Leu Glu Glu Leu Gln Glu Val 385 390 395 400

age age agt ctg cag att tat acg tat cgt get caa ctg ctt aag gct Arg Arg Ser Leu Pro Ile Tyr Thr Tyr Arg Asp Gln Leu Leu Lys Ala 405 410 415

gtg gaa gag cat cag gtt ctt gtc att gtg gga gac act ggt lea gga Val Glu Glu His Gln Val Leu Val Ile Val Gly Asp Thr Gly Ser Gly 420 425 430

aaa aeg ace caa ata cca caa tat ctc cat gaa get ggt tac ace aag

-224 Lys Thr Thr Gln Ile Pro Gln Tyr Leu His Glu Ala Gly Tyr Thr Lys 435 440 445

cgt gga aag gUt ggt tgt acg cag ccc cga age gtt gca gct atg agt Arg Gly Lys Val Gly Cys Thr Gln Pro Arg Arg Val Ala Ala Met Ser 450 455 460

gtt gct gcc cgt gtg gct caa gag atg ggt gtc aaa ctc gga cat gag Val Ala Ala Arg Val Ala Gln Glu Met Gly Val Lys Leu Gly His Glu 465 470 475 480

ght ggc tat tcc att cga ttt gag get tgt act lea gac aaa ace gtt Val Gly Tyr Ser Ile Arg Phe Glu Asp Cys Thr Ser Asp Lys Thr Val 485 490 495

ctg aag tat atg act get gga atg ctt ttg cgc gag ctg ctt ggt gag Leu Lys Tyr Met Thr Asp Gly Met Leu Leu Arg Glu Leu Leu Gly Glu 500 505 510

cca gac ctg gac agc tac agt gtc gtt att gUg get gag gca cat gaa Pro Asp Leu Ala Ser Tyr Ser Val Val Ile Val Asp Glu Ala His Glu 515 520 525

agg acc ttg lea acc get ata ctg tht gga tta gtc aag get ata gcg Arg Thr Leu Ser Thr Asp Ile Leu Phe Gly Leu Val Lys Asp Ile Ala 530 535 540

cgg ttt cga cct get ttg aag ttg ttg ata let agt goa ace aUg get Arg Phe Arg Pro Asp Leu Lys Leu Leu Ile Ser Ser Ala Thr Met Asp 545 550 555 560

goa gaa aaa ttt let get tat ttt get ace gcc ccg att ttt agt ttt Ala Glu Lys Phe Ser Asp Tyr Phe Asp Thr Ala Pro Ile Phe Ser Phe 565 570 575

cat gga age agg tat cca gtt gaa ale aac tat ace agt gca cat gaa Pro Gly Arg Arg Tyr Pro Val Glu Ile Asn Tyr Thr Ser Ala Pro Glu 580 585 590

get get tac atg gac gca gcc ata gtt act ale ctt acg ale cat gtg

-225 Ala Asp Tyr Met Asp Ala Ala Ile Val Thr Ile Leu Thr Ile His Val 595 600 605

agg gag cca ctt gga get ata ttg gtc ttc ttc act ggt caa gag gaa Arg Glu Pro Leu Gly Asp Ile Leu Val Phe Phe Thr Gly Gln Glu Glu 610 615 620

att gaa act gca gaa gag ale ttg aag cac agg ata age ggt ttg ggt Ile Glu Thr Ala Glu Glu Ile Leu Lys His Arg Ile Arg Gly Leu Gly 625 630 635 640

ace aag ale cgt gaa tta ale ata tgc cca att tac gca eat ctt cca Thr Lys Ile Arg Glu Leu Ile Ile Cys Pro Ile Tyr Ala Asn Leu Pro 645 650 655

agt gaa ctc caa gca aaa ata ttt gag cca act cca gaa ggg goa cgt Ser Glu Leu Gln Ala Lys Ile Phe Glu Pro Thr Pro Glu Gly Ala Arg 660 665 670

aaa gtt gtc cta gca ace eat ale gac gaa ace lea ttg ace att get Lys Val Val Leu Ala Thr Asn Ile Ala Glu Thr Ser Leu Thr Ile Asp 675 680 685

ggt ata aag tat gtt gtt get cca ggc ttt agc aag atg aag lea tat Gly Ile Lys Tyr Val Val Asp Pro Gly Phe Ser Lys Met Lys Ser Tyr 690 695 700

aac cag agg ace ggg atg gaa let ttg cht att act cat ale tat aag Asn Pro Arg Thr Gly Met Glu Ser Leu Leu Ile Thr Pro Ile Ser Lys 705 710 715 720

get let goa act caa cga gct ggt cgt gct gga age ace agt cca ggg Ala Ser Ala Thr Gln Arg Ala Gly Arg Ala Gly Arg Thr Ser Pro Gly 725 730 735

aag tgt tat cgt ctg tac act gag ttt eat tac aac eat gac ttg gag Lys Cys Tyr Arg Leu Tyr Thr Ala Phe Asn Tyr Asn Asn Asp Leu Glu 740 745 750

gaa aac aeg gtg cca gaa gLa cag agg acg eat cEt gct agt gtg gtg

-226 Glu Asn Thr Val Pro Glu Val Gln Arg Thr Asn Leu Ala Ser Val Val 755 760 765

ctt gct ttg aag agt ctt gga att cat get ctc ata aac tUc get thc Leu Ala Leu Lys Ser Leu Gly Ile His Asp Leu Ile Asn Phe Asp Phe 770 775 780

atg gac cct cca cct get gaa gca ctt gta aag let tta gaa ctg ctc Met Asp Pro Pro Pro Ala Glu Ala Leu Val Lys Ser Leu Glu Leu Leu 785 790 795 800

ttt gct chg ggt get cta eat aag ctc ggg gaa ttg act aaa gct ggt Phe Ala Leu Gly Ala Leu Asn Lys Leu Gly Glu Leu Thr Lys Ala Gly 805 810 815

age agg atg gca gag ttc ccc cUt get cca atg ctg tag aaa atg att Arg Arg Met Ala Glu Phe Pro Leu Asp Pro Met Leu Ser Lys Met Ile 820 825 830

gtt gtt let gac aag tat aag tgc tcc get gag ata ata lea ale gct Val Val Ser Asp Lys Tyr Lys Cys Ser Asp Glu Ile Ile Ser Ile Ala 835 840 845

get atg ttg lea att ggt ggc tat ale thc tac cgt ccc aag gac aaa Ala Met Leu Ser Ile Gly Gly Ser Ile Phe Tyr Arg Pro Lys Asp Lys 850 855 860

caa gtt cat gag gac aac gca age atg eat thc cac acc ggg eat gtc Gln Val His Ala Asp Asn Ala Arg Met Asn Phe His Thr Gly Asn Val 865 870 875 880

ggt gac cat att gct ttg cta aag ght tac agt lea tgg aag gaa ace Gly Asp His Ile Ala Leu Leu Lys Val Tyr Ser Ser Trp Lys Glu Thr 885 890 895

aac ttc tat act cag tgg tgc tac gag aac tac att cag gtc cgg agc Asn Phe Ser Thr Gln Trp Cys Tyr Glu Asn Tyr Ile Gln Val Arg Ser 900 905 910

aLg aaa age gcc age get ale cgt get caa ttg gag gga ctt ctc gaa

-227 Met Lys Arg Ala Arg Asp Ile Arg Asp Gln Leu Glu Gly Leu Leu Glu 915 920 925

agg gtg gaa ata get ale agc lea aac ctg eat gaa ttg get lea gUt Arg Val Glu Ile Asp Ile Ser Ser Asn Leu Asn Glu Leu Asp Ser Val 930 935 940

age aaa tcc ale gta gcc ggg ttt ttt ccg cac act gca aag cta cag Arg Lys Ser Ile Val Ala Gly Phe Phe Pro His Thr Ala Lys Leu Gln 945 950 955 960

aag eat gga leg tac cga ace gtg aaa cat ccc cag ace gtg cac ata Lys Asn Gly Ser Tyr Arg Thr Val Lys His Pro Gln Thr Val His Ile 965 970 975

cat ccc eat leg ggc tta let cag gta ttg ccg age tgg gtt gta tat His Pro Asn Ser Gly Leu Ser Gln Val Leu Pro Arg Trp Val Val Tyr 980 985 990

cac gaa cta gLa ctt acg tcc aag gaa tac atg cga cag gta ace gag His Glu Leu Val Leu Thr Ser Lys Glu Tyr Met Arg Gln Val Thr Glu 995 1000 1005

ttg aaa cca gag tgg ttg att gag tta gct cct cac tac tac cag Leu Lys Pro Glu Trp Leu Ile Glu Leu Ala Pro His Tyr Tyr Gln 1010 1015 1020

ctc aag gac gtt gaa gac get gca lea aag aaa atg cac aaa gga Leu Lys Asp Val Glu Asp Ala Ala Ser Lys Lys Met Pro Lys Gly 1025 1030 1035

gct gga aaa get gca atg tea Ala Gly Lys Ala Ala Met <210> 56

<211> 1044

<212> PRT

-228 <213> Arabidopsis thaliana <400> 56

Met Ala Ser Asn Asp Leu Lys Thr Trp Val Ser Asp Lys Leu Met Met 1 5 10 15

Leu Leu Gly Tyr Ser Gln Ala Ala Val Val Asn Tyr Leu Ile Ala Met 20 25 30

Ala Lys Lys Thr Lys Ser Pro Thr Glu Leu Val Gly Glu Leu Val Asp 35 40 45

Tyr Gly Phe Ser Ser Ser Gly Asp Thr Arg Ser Phe Ala Glu Glu Ile 50 55 60

Phe Ala Arg Val Pro Arg Lys Thr Ala Gly Val Asn Leu Tyr Gln Lys 65 70 75 80

His Glu Ala Glu Ala Ala Met Leu Val Arg Lys Gln Lys Thr Tyr Ala 85 90 95

Leu Leu Asp Ala Asp Asp Asp Glu Asp Glu Val Val Val Glu Lys Lys 100 105 110

Ser Ser Val Ser Glu Ser Arg Lys Ser Asp Lys Gly Lys Lys Arg Phe 115 120 125

Arg Lys Lys Ser Gly Gln Ser Asp Glu Ser Asp Gly Glu Val Ala Val 130 135 140

Arg Glu Asp Ser Arg His Val Arg Arg Lys Val Ser Glu Glu Asp Asp 145 150 155 160

Gly Ser Glu Ser Glu Glu Glu Arg Val Arg Asp Gln Lys Glu Arg Glu 165 170 175

-229 Glu Leu Glu Gln His Leu Lys Asp Arg Asp Thr Ala Arg Thr Arg Ly Leu Thr Glu Gln Thr Leu Ser Lys Lys Glu Lys Glu Glu Ala Val Arg 195 200 205

Arg Ala Asn Ala Leu Glu Lys Asp Asp Leu Tyr Ser Leu Arg Lys Val Ser Arg Gln Glu Tyr Leu Lys Lys Arg Glu Gln Lys Lys Leu Asp Glu Leu Arg Asp Glu Ile Glu Asp Glu Gln Tyr Leu Phe Gly Gly Glu Lys Leu Thr Glu Thr Glu Leu Arg Glu Phe Arg Tyr Lys Lys Glu Leu Tyr Asp Leu Val Lys Lys Arg Thr Gln Asp Glu Asp Asn Val Glu Glu Tyr Arg Ile Pro Asp Ala Tyr Asp Gln Glu Gly Gly Val Asp Gln Glu Lys Arg Phe Ser Val Ala Val Gln Arg Tyr Arg Asp Leu Asp Ser Thr Glu Lys Met Asn Pro Phe Ala Glu Gln Glu Ala Trp Glu Asp His Gln Ile Gly Lys Ala Thr Leu Lys Phe Gly Ala Lys Asn Lys Gln Ala Ser Asp Asp Tyr Gln Phe Val Phe Glu Asp Gln Ile Asn Phe Ile Lys Glu Ser 360 365

Val Met Ala Gly Glu Asn Tyr Glu Asp Ala Met Asp Ala Lys Gln Lys

-230 Ser Gln Asp Leu Ala Glu Lys Thr Ala Leu Glu Glu Leu Gln Glu Val 385 390 395 400

Arg Arg Ser Leu Pro Ile Tyr Thr Tyr Arg Asp Gln Leu Leu Lys Ala 405 410 415

Val Glu Glu His Gln Val Leu Val Ile Val Gly Asp Thr Gly Ser Gly 420 425 430

Lys Thr Thr Gln Ile Pro Gln Tyr Leu His Glu Ala Gly Tyr Thr Lys 435 440 445

Arg Gly Lys Val Gly Cys Thr Gln Pro Arg Arg Val Ala Ala Met Ser 450 455 460

Val Ala Ala Arg Val Ala Gln Glu Met Gly Val Lys Leu Gly His Glu 465 470 475 480

Val Gly Tyr Ser Ile Arg Phe Glu Asp Cys Thr Ser Asp Lys Thr Val 485 490 495

Leu Lys Tyr Met Thr Asp Gly Met Leu Leu Arg Glu Leu Leu Gly Glu 500 505 510

Pro Asp Leu Ala Ser Tyr Ser Val Val Ile Val Asp Glu Ala His Glu 515 520 525 Arg Thr Leu Ser Thr Asp Ile Leu Phe Gly Leu Val Lys Asp Ile Ala 530 535

540

Arg Phe Arg Pro Asp Leu Lys Leu Leu Ile Ser Ser Ala Thr Met Asp 545 550 555 560

Ala Glu Lys Phe Ser Asp Tyr Phe Asp Thr Ala Pro Ile Phe Ser Phe 565 570 575

-231 Pro Gly Arg Arg Tyr Pro Val Glu Ile Asn Tyr Thr Ser Ala Pro Glu 580 585 590

Ala Asp Tyr Met Asp Ala Ala Ile Val Thr Ile Leu Thr Ile His Val 595 600 605

Arg Glu Pro Leu Gly Asp Ile Leu Val Phe Phe Thr Gly Gln Glu Glu 610 615 620

Ile Glu Thr Ala Glu Glu Ile Leu Lys His Arg Ile Arg Gly Leu Gly 625 630 635 640

Thr Lys Ile Arg Glu Leu Ile Ile Cys Pro Ile Tyr Ala Asn Leu Pro 645 650 655

Ser Glu Leu Gln Ala Lys Ile Phe Glu Pro Thr Pro Glu Gly Ala Arg 660 665 670

Lys Val Val Leu Ala Thr Asn Ile Ala Glu Thr Ser Leu Thr Ile Asp 675 680 685

Gly Ile Lys Tyr Val Val Asp Pro Gly Phe Ser Lys Met Lys Ser Tyr 690 695 700

Asn Pro Arg Thr Gly Met Glu Ser Leu Leu Ile Thr Pro Ile Ser Lys 705 710 715 720

Ala Ser Ala Thr Gln Arg Ala Gly Arg Ala Gly Arg Thr Ser Pro Gly 725 730 735

Lys Cys Tyr Arg Leu Tyr Thr Ala Phe Asn Tyr Asn Asn Asp Leu Glu 740 745 750

Glu Asn Thr Val Pro Glu Val Gln Arg Thr Asn Leu Ala Ser Val Val 755 760 765

Leu Ala Leu Lys Ser Leu Gly Ile His Asp Leu Ile Asn Phe Asp Phe 770 775 780

-232 Met Asp Pro Pro Pro Ala Glu Ala Leu Val Lys Ser Leu Glu Leu Leu 785 790 795 800

Phe Ala Leu Gly Ala Leu Asn Lys Leu Gly Glu Leu Thr Lys Ala Gly 805 810 815

Arg Arg Met Ala Glu Phe Pro Leu Asp Pro Met Leu Ser Lys Met Ile 820 825 830

Val Val Ser Asp Lys Tyr Lys Cys Ser Asp Glu Ile Ile Ser Ile Ala 835 840 845

Ala Met Leu Ser Ile Gly Gly Ser Ile Phe Tyr Arg Pro Lys Asp Lys 850 855 860

Gln Val His Ala Asp Asn Ala Arg Met Asn Phe His Thr Gly Asn Val 865 870 875 880

Gly Asp His Ile Ala Leu Leu Lys Val Tyr Ser Ser Trp Lys Glu Thr 885 890 895

Asn Phe Ser Thr Gln Trp Cys Tyr Glu Asn Tyr Ile Gln Val Arg Ser 900 905 910

Met Lys Arg Ala Arg Asp Ile Arg Asp Gln Leu Glu Gly Leu Leu Glu 915 920 925

Arg Val Glu Ile Asp Ile Ser Ser Asn Leu Asn Glu Leu Asp Ser Val 930 935 940

Arg Lys Ser Ile Val Ala Gly Phe Phe Pro His Thr Ala Lys Leu Gln 945 950 955 960

Lys Asn Gly Ser Tyr Arg Thr Val Lys His Pro Gln Thr Val His Ile 965 970 975

-233 His Pro Asn Ser Gly Leu Ser Gln Val Leu Pro Arg Trp Val Val Tyr 980 985 990

His Glu Leu Val Leu Thr Ser Lys Glu Tyr Met Arg Gln Val Thr Glu 995 1000 1005

Leu Lys Pro Glu Trp Leu Ile Glu Leu Ala Pro His Tyr Tyr Gln 1010 1015 1020

Leu Lys Asp Val Glu Asp Ala Ala Ser Lys Lys Met Pro Lys Gly 1025 1030 1035

Ala Gly Lys Ala Ala Met <210> 57

<211> 1449

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1449)

<223> <400> 57

atg lea gac tcc gtc gcc gtc gtg tag ggt ttt ctc cgt ale ccg lea Met Ser Ala Ser Val Ala Val Val Ser Gly Phe Leu Arg Ile Pro Ser 1 5 10 15

att caa aag let caa aac cat tcc ttt ctc ttt let cga cac aag aaa Ile Gln Lys Ser Gln Asn Pro Ser Phe Leu Phe Ser Arg Pro Lys Lys 20 25 30

-234 tct ttg gtg aga ccc att tca gct tca agc tca gag ttg ccg gaa aat Ser Leu Val Arg Pro Ile Ser Ala Ser Ser Ser Glu Leu Pro Glu Asn 35 40 45

gtt cgg aat ttc tgg aaa tgg ctc aga gac caa gga gtc gta tcc ggg Val Arg Asn Phe Trp Lys Trp Leu Arg Asp Gln Gly Val Val Ser Gly 50 55 60

aag tct gtg gca gaa cct gcg gtg gta ccg gaa ggt ttg gga ctt gta Lys Ser Val Ala Glu Pro Ala Val Val Pro Glu Gly Leu Gly Leu Val 65 70 75 80

gcc agg cgt gat att gga aga aac gag gtc gta ttg gag att cac aag Ala Arg Arg Asp Ile Gly Arg Asn Glu Val Val Leu Glu Ile Pro Lys 85 90 95

cga ttg tgg ata aac cca gag aca gtg act gct tcc aag att gga cct Arg Leu Trp Ile Asn Pro Glu Thr Val Thr Ala Ser Lys Ile Gly Pro 100 105 110

tta tgc ggc gga tta aag ccg tgg gtt tca gta gct ctg ttt ttg atc Leu Cys Gly Gly Leu Lys Pro Trp Val Ser Val Ala Leu Phe Leu Ile 115 120 125

aga gag aag tat gaa gaa gag tct tca tgg aga gtt tat ctt gat atg Arg Glu Lys Tyr Glu Glu Glu Ser Ser Trp Arg Val Tyr Leu Asp Met 130 135 140

ctt cat caa tat act gat tct act gtc ttc tgg tca gaa gag gag ctt Leu Pro Gln Ser Thr Asp Ser Thr Val Phe Trp Ser Glu Glu Glu Leu 145 150 155 160

gat gag ctt aaa ggg act caa ctg ttg agc acc aca ttg ggt gtg aaa Ala Glu Leu Lys Gly Thr Gln Leu Leu Ser Thr Thr Leu Gly Val Lys 165 170 175

gag tat gUg gag aat gaa ttc ttg aaa ctg gaa caa gag ata tta ctg Glu Tyr Val Glu Asn Glu Phe Leu Lys Leu Glu Gln Glu Ile Leu Leu 180 185 190

-235 cct aac aaa get ctc ttc lea tcc cgc ata ace ctt get gac ttc ata Pro Asn Lys Asp Leu Phe Ser Ser Arg Ile Thr Leu Asp Asp Phe Ile 195 200 205

tgg gcg ttt ggg ale ctc aag leg agg gct ttt let cgt ctc cgt ggc Trp Ala Phe Gly Ile Leu Lys Ser Arg Ala Phe Ser Arg Leu Arg Gly 210 215 220

caa aac ctt gtc ttg ale cct cUt gca gac ttg ata aac cat aac ccc Gln Asn Leu Val Leu Ile Pro Leu Ala Asp Leu Ile Asn His Asn Pro 225 230 235 240

gcg ata aag ace gaa get tat gca tac gag ale aaa gga gcc ggc ctt Ala Ile Lys Thr Glu Asp Tyr Ala Tyr Glu Ile Lys Gly Ala Gly Leu 245 250 255

ttc let age get ctc tta ttt tcc ttg aag lea cct gtt tat gtt aaa Phe Ser Arg Asp Leu Leu Phe Ser Leu Lys Ser Pro Val Tyr Val Lys 260 265 270

gca ggt gag cag gta tac att cag tac get ctg aac aaa agc eat gca Ala Gly Glu Gln Val Tyr Ile Gln Tyr Asp Leu Asn Lys Ser Asn Ala 275 280 285

gaa ctt gct ctc gac tat ggt ttt gtg gaa lea aac cct aaa cgg aac Glu Leu Ala Leu Asp Tyr Gly Phe Val Glu Ser Asn Pro Lys Arg Asn 290 295 300

lea tat act tta ace ata gag ata cca gaa lea gac cca ttc ttt ggg Ser Tyr Thr Leu Thr Ile Glu Ile Pro Glu Ser Asp Pro Phe Phe Gly 305 310 315 320

get aag ttg get att gct gag agt aac aag aLg ggt gag acc gga tac Asp Lys Leu Asp Ile Ala Glu Ser Asn Lys Met Gly Glu Thr Gly Tyr 325 330 335

ttt gac ata gta gac ggc cag act cUt ccc gct ggt atg cUt cag tac Phe Asp Ile Val Asp Gly Gln Thr Leu Pro Ala Gly Met Leu Gln Tyr 340 345 350

-236 ctt cgg cUt gtg gct ctt ggc ggt cca gat gct ttc tta tta gaa tct Leu Arg Leu Val Ala Leu Gly Gly Pro Asp Ala Phe Leu Leu Glu Ser 355 360 365

atc ttc aat aac acc ata tgg ggt cat ctt gaa ttg cct gLa agt cgt Ile Phe Asn Asn Thr Ile Trp Gly His Leu Glu Leu Pro Val Ser Arg 370 375 380

aca aac gag gaa ctc ata tgc cgt gtt gtc aga gat gcc tgc aaa tct Thr Asn Glu Glu Leu Ile Cys Arg Val Val Arg Asp Ala Cys Lys Ser 385 390 395 400

gct ctg tct ggt tUt gat acg acc att gaa gag gat gag aag ctt ctg Ala Leu Ser Gly Phe Asp Thr Thr Ile Glu Glu Asp Glu Lys Leu Leu 405 410 415

gac aaa gga aag cht gag cct agg ttg gaa aUg gct ctc aag ata agg Asp Lys Gly Lys Leu Glu Pro Arg Leu Glu Met Ala Leu Lys Ile Arg 420 425 430

att ggt gag aag aga gtg ctt cag caa atc gac caa atc ttc aag gat Ile Gly Glu Lys Arg Val Leu Gln Gln Ile Asp Gln Ile Phe Lys Asp 435 440 445

aga gag ctt gaa ctt gac att tta gag tat tac caa gag aga agg ctc Arg Glu Leu Glu Leu Asp Ile Leu Glu Tyr Tyr Gln Glu Arg Arg Leu 450 455 460

aaa gat cUt ggg ttg gtt ggc gaa caa ggg gat att atc ttc tgg gaa Lys Asp Leu Gly Leu Val Gly Glu Gln Gly Asp Ile Ile Phe Trp Glu 465 470 475 480

acc aag tga Thr Lys <210> 58

-237 <211> 482

c212> PRT <213> Arabidopsis thaliana <400> 58

Met Ser Ala Ser Val Ala Val Val Ser Gly Phe Leu Arg Ile Pro Ser 1 5 10 15

Ile Gln Lys Ser Gln Asn Pro Ser Phe Leu Phe Ser Arg Pro Lys Lys 20 25 30

Ser Leu Val Arg Pro Ile Ser Ala Ser Ser Ser Glu Leu Pro Glu Asn 35 40 45

Val Arg Asn Phe Trp Lys Trp Leu Arg Asp Gln Gly Val Val Ser Gly 50 55 60

Lys Ser Val Ala Glu Pro Ala Val Val Pro Glu Gly Leu Gly Leu Val 65 70 75 80

Ala Arg Arg Asp Ile Gly Arg Asn Glu Val Val Leu Glu Ile Pro Lys 85 90 95

Arg Leu Trp Ile Asn Pro Glu Thr Val Thr Ala Ser Lys Ile Gly Pro 100 105 110

Leu Cys Gly Gly Leu Lys Pro Trp Val Ser Val Ala Leu Phe Leu Ile Arg Glu Lys Tyr Glu Glu Glu Ser Ser Trp Arg Val Tyr Leu Asp Met 130 135 140

Leu Pro Gln Ser Thr Asp Ser Thr Val Phe Trp Ser Glu Glu Glu Leu 145 150 155 160

-238 Ala Glu Leu Lys Gly Thr Gln Leu Leu Ser Thr Thr Leu Gly Val Lys 165 170 175

Glu Tyr Val Glu Asn Glu Phe Leu Lys Leu Glu Gln Glu Ile Leu Leu 180 185 190

Pro Asn Lys Asp Leu Phe Ser Ser Arg Ile Thr Leu Asp Asp Phe Ile 195 200 205

Trp Ala Phe Gly Ile Leu Lys Ser Arg Ala Phe Ser Arg Leu Arg Gly 210 215 220

* Gln Asn Leu Vai Leu Ile Pro Leu Ala Asp Leu Ile Asn His Asn Pro 225 230 235 240

Ala Ile Lys Thr Glu Asp Tyr Ala Tyr Glu Ile Lys Gly Ala Gly Leu 245 250 255

Phe Ser Arg Asp Leu Leu Phe Ser Leu Lys Ser Pro Val Tyr Val Lys 260 265 270

Ala Gly Glu Gln Val Tyr Ile Gln Tyr Asp Leu Asn Lys Ser Asn Ala 275 280 285

Glu Leu Ala Leu Asp Tyr Gly Phe Val Glu Ser Asn Pro Lys Arg Asn 290 295 300

Ser Tyr Thr Leu Thr Ile Glu Ile Pro Glu Ser Asp Pro Phe Phe Gly 305 310 315 320

Asp Lys Leu Asp Ile Ala Glu Ser Asn Lys Met Gly Glu Thr Gly Tyr 325 330 335

Phe Asp Ile Val Asp Gly Gln Thr Leu Pro Ala Gly Met Leu Gln Tyr 340 345 350

Leu Arg Leu Val Ala Leu Gly Gly Pro Asp Ala Phe Leu Leu Glu Ser 355 360 365

-239 Ile Phe Asn Asn Thr Ile Trp Gly His Leu Glu Leu Pro Val Ser Arg Thr Asn Glu Glu Leu Ile Cys Arg Val Val Arg Asp Ala Cys Lys Ser Ala Leu Ser Gly Phe Asp Thr Thr Ile Glu Glu Asp Glu Lys Leu Leu Asp Lys Gly Lys Leu Glu Pro Arg Leu Glu Met Ala Leu Lys Ile Arg Ile Gly Glu Lys Arg Val Leu Gln Gln Ile Asp Gln Ile Phe Lys Asp 435 440 445

Arg Glu Leu Glu Leu Asp Ile Leu Glu Tyr Tyr Gln Glu Arg Arg Leu Lys Asp Leu Gly Leu Val Gly Glu Gln Gly Asp Ile Ile Phe Trp Glu Thr Lys <210> 59

<211> 3516

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1) (3516)

-240 <223> <400> 59

atg aac act cht ccc gtc gtc let ctc ace gct let let tcc ttc aaa Met Asn Thr Leu Pro Val Val Ser Leu Thr Ala Ser Ser Ser Phe Lys 1 5 10 15

ttc ttc cat ttt cct let ctg cac cgt let ctc let cat tcc cca aac Phe Phe His Phe Pro Ser Leu His Arg Ser Leu Ser His Ser Pro Asn 20 25 30

ttc tcc ttc acc aaa tcc ctt ale ctc eat cca aac cac ctc tcc ttc Phe Ser Phe Thr Lys Ser Leu Ile Leu Asn Pro Asn His Leu Ser Phe 35 40 45

aaa tcc acc tta eat let ctt lea ccg let cag let cag ctc tac gag Lys Ser Thr Leu Asn Ser Leu Ser Pro Ser Gln Ser Gln Leu Tyr Glu 50 55 60

gaa gaa gac gac gaa gaa gaa gaa gaa gaa gac gaa get get get gac Glu Glu Asp Asp Glu Glu Glu Glu Glu Glu Asp Glu Asp Asp Asp Asp 65 70 75 80

gaa gct get gac gaa tac gac eat ale tcc get gaa att cgg eat agc Glu Ala Ala Asp Glu Tyr Asp Asn Ile Ser Asp Glu Ile Arg Asn Ser 85 90 95

get gac gac gac gac get gaa gaa acc gaa ttc tcc gUg get ttg ccg Asp Asp Asp Asp Asp Asp Glu Glu Thr Glu Phe Ser Val Asp Leu Pro 100 105 110

acg gaa lea gct cgg gaa cga gtg gag ttc cgg tgg cag age gtg gag Thr Glu Ser Ala Arg Glu Arg Val Glu Phe Arg Trp Gln Arg Val Glu 115 120 125

aag cEt cgt agt cUt gtt age get ttt ggt gtt gag atg att get ale Lys Leu Arg Ser Leu Val Arg Asp Phe Gly Val Glu Met Ile Asp Ile 130 135 140

-241 gat gaa ctc att lea ale tac get tUt cga ale gac aag ttt cag age Asp Glu Leu Ile Ser Ile Tyr Asp Phe Arg Ile Asp Lys Phe Gln Arg 145 150 155 160

ttg gct att gaa gct ttt ctt age ggt let let gtt gtg gtt let gct Leu Ala Ile Glu Ala Phe Leu Arg Gly Ser Ser Val Val Val Ser Ala 165 170 175

ccg act agt agt ggc aag act ttg att gct gaa gct get gct gtt tcc Pro Thr Ser Ser Gly Lys Thr Leu Ile Ala Glu Ala Ala Ala Val Ser 180 185 190

aeg gtg gct aaa ggt cgc cgg ttg tUc tac act ace cct ctt aaa gca Thr Val Ala Lys Gly Arg Arg Leu Phe Tyr Thr Thr Pro Leu Lys Ala 195 200 205

ctc let eat cag aag tUt cgt gag ttt agg gag ace ttt ggg get get Leu Ser Asn Gln Lys Phe Arg Glu Phe Arg Glu Thr Phe Gly Asp Asp 210 215 220

eat gUt ggt tta ctc ace ggt gac let get att aac aaa get gct cag Asn Val Gly Leu Leu Thr Gly Asp Ser Asp Ile Asn Lys Asp Ala Gln 225 230 235 240

att gtg att aUg act ace gag att ctc cgt aac atg ttg tat caa agt Ile Val Ile Met Thr Thr Glu Ile Leu Arg Asn Met Leu Tyr Gln Ser 245 250 255

gtt gga aUg get let lea gga act gga ctt tUt cat gtt get gcc att Val Gly Met Ala Ser Ser Gly Thr Gly Leu Phe His Val Asp Ala Ile 260 265 270

gtt ttg get gag ght cac tat tta agt get ata tat agg gga act gtg Val Leu Asp Glu Val His Tyr Leu Ser Asp Ile Ser Arg Gly Thr Val 275 280 285

tgg gaa gag ata gtc att tat tgt cca aag gag gtt caa ctt ata tgc Trp Glu Glu Ile Val Ile Tyr Cys Pro Lys Glu Val Gln Leu Ile Cys 290 295 300

-242 cta tca gct aca gtt gca aat ccg gat gaa tta gct ggt tgg att ggt Leu Ser Ala Thr Val Ala Asn Pro Asp Glu Leu Ala Gly Trp Ile Gly 305 310 315 320

gag ata cat ggt aaa act gag ttg gta aca tcg aca aga cgc cca gtt Glu Ile His Gly Lys Thr Glu Leu Val Thr Ser Thr Arg Arg Pro Val 325 330 335

cca tta act tgg tac ttt tca aca aaa cat tct tta tta cct ctg cht Pro Leu Thr Trp Tyr Phe Ser Thr Lys His Ser Leu Leu Pro Leu Leu 340 345 350

gat gag aaa ggg ata aac gtg aat agg aag ctt tct ctc aat tat ttg Asp Glu Lys Gly Ile Asn Val Asn Arg Lys Leu Ser Leu Asn Tyr Leu 355 360 365

caa ctg tct gcc tca gaa gct aga ttc cgt gat gat gat gac ggg tat Gln Leu Ser Ala Ser Glu Ala Arg Phe Arg Asp Asp Asp Asp Gly Tyr 370 375 380

agg aaa agg agg tca aag aaa cga gga ggt gat acc agc tac aac aac Arg Lys Arg Arg Ser Lys Lys Arg Gly Gly Asp Thr Ser Tyr Asn Asn 385 390 395 400

ctt gtg aac gta act gat tat cat ctt tca aag aat gag ata aac aag Leu Val Asn Val Thr Asp Tyr Pro Leu Ser Lys Asn Glu Ile Asn Lys 405 410 415

att cgt cga tca cag gta cct caa att agc gac aca tta tgg cat ctc Ile Arg Arg Ser Gln Val Pro Gln Ile Ser Asp Thr Leu Trp His Leu 420 425 430

cag ggg aaa aat atg tta cca gcg ata tgg ttc att ttt aac cgt aga Gln Gly Lys Asn Met Leu Pro Ala Ile Trp Phe Ile Phe Asn Arg Arg 435 440 445

gga tgt gat gca gct gta cag tat gtt gaa aat ttt cag ctt tta gat Gly Cys Asp Ala Ala Val Gln Tyr Val Glu Asn Phe Gln Leu Leu Asp 450 455 460

-243 gat tgc gag aag agt gag gtt gag ttg gcc ttg aag aag ttt cgc gtt Asp Cys Glu Lys Ser Glu Val Glu Leu Ala Leu Lys Lys Phe Arg Val 465 470 475 480

ctt tat cca get gca gtg age gag agt gca gag aaa gga ctg ctt agg Leu Tyr Pro Asp Ala Val Arg Glu Ser Ala Glu Lys Gly Leu Leu Arg 485 490 495

gga att gct get cat cat goa ggt tgt cta cct cht tgg aaa let tUc Gly Ile Ala Ala His His Ala Gly Cys Leu Pro Leu Trp Lys Ser Phe 500 505 510

att gag gaa ctt tht cag cga gga cUt gtt aag gtt gtc ttt gct act Ile Glu Glu Leu Phe Gln Arg Gly Leu Val Lys Val Val Phe Ala Thr 515 520 525

gag ace cht gct gct gga ata aac atg ccg gct age acg gct gtt ale Glu Thr Leu Ala Ala Gly Ile Asn Met Pro Ala Arg Thr Ala Val Ile 530 535 540

leg let ctt lea aaa aag gct ggt eat gaa cga ata gag ttg ggt cct Ser Ser Leu Ser Lys Lys Ala Gly Asn Glu Arg Ile Glu Leu Gly Pro 545 550 555 560

aac gaa ttg tac cag atg get ggg cgt gct gga cgc age ggc ale get Asn Glu Leu Tyr Gln Met Ala Gly Arg Ala Gly Arg Arg Gly Ile Asp 565 570 575

gaa aag ggc tac act gtg ctg gtt cag act get ttt gaa ggc gct gaa Glu Lys Gly Tyr Thr Val Leu Val Gln Thr Ala Phe Glu Gly Ala Glu 580 585 590

gag tgc tgc aaa cht gtc ttt get gga gtt aaa cct ctc gtg lea caa Glu Cys Cys Lys Leu Val Phe Ala Gly Val Lys Pro Leu Val Ser Gln 595 600 605

ttt act gct lea tat ggc atg gta ctg eat ctg gta get ggt lea aaa Phe Thr Ala Ser Tyr Gly Met Val Leu Asn Leu Val Ala Gly Ser Lys 610 615 620

-244 gtt act cgt aaa tca agt gga act gag gcc ggg aaa gtc tta caa goa Val Thr Arg Lys Ser Ser Gly Thr Glu Ala Gly Lys Val Leu Gln Ala 625 630 635 640

ggg aga agt ctg gaa gaa gcc aag aaa tta gtt gag aag agt ttt gga Gly Arg Ser Leu Glu Glu Ala Lys Lys Leu Val Glu Lys Ser Phe Gly 645 650 655

aac tat gUg agc agc aat gtg acg gtt gct gcg aag cag gaa ctt gct Asn Tyr Val Ser Ser Asn Val Thr Val Ala Ala Lys Gln Glu Leu Ala 660 665 670

gaa atc gac aat aag atc gag att ctg tca tct gaa ata agt gat gaa Glu Ile Asp Asn Lys Ile Glu Ile Leu Ser Ser Glu Ile Ser Asp Glu 675 680 685

goa ata gat aag aag agt agg aaa ctt ctt tca gcg agg gat tac aag Ala Ile Asp Lys Lys Ser Arg Lys Leu Leu Ser Ala Arg Asp Tyr Lys 690 695 700

gag atc act gta ctt aaa gaa gag cta cgg gaa gag aaa cgc aag cgt Glu Ile Thr Val Leu Lys Glu Glu Leu Arg Glu Glu Lys Arg Lys Arg 705 710 715 720

gct gaa caa cga aga aga atg gaa ctc gaa agg ttc tta gct cta aaa Ala Glu Gln Arg Arg Arg Met Glu Leu Glu Arg Phe Leu Ala Leu Lys 725 730 735

cag ctc tta aaa ggg atg gaa gag ggg aac tta cca tht att tgt ttg Pro Leu Leu Lys Gly Met Glu Glu Gly Asn Leu Pro Phe Ile Cys Leu 740 745 750

gag ttc aag gat tct gaa ggg agg gag cag tca gtc cct gct gtt tac Glu Phe Lys Asp Ser Glu Gly Arg Glu Gln Ser Val Pro Ala Val Tyr 755 760 765

ttg ggg cat att gat tca tEt cag ggt tcc aaa cht cag aag atg atg Leu Gly His Ile Asp Ser Phe Gln Gly Ser Lys Leu Gln Lys Met Met 770 775 780

-245 tct ttg get gag let ttt gcg tta aac tta ale gag get gag ctg gcg Ser Leu Asp Glu Ser Phe Ala Leu Asn Leu Ile Glu Asp Glu Leu Ala 785 790 795 800

gct get gaa cct gga aag cct eat gtt aaa ccg let tac tat gtg gcc Ala Asp Glu Pro Gly Lys Pro Asn Val Lys Pro Ser Tyr Tyr Val Ala 805 810 815

cUt ggc let get aac lea tgg tat ctc tUt act gag aag tgg gtt agg Leu Gly Ser Asp Asn Ser Trp Tyr Leu Phe Thr Glu Lys Trp Val Arg 820 825 830

act gtc tac age act ggt ttc cat aac att gct cta gcg ctt gga get Thr Val Tyr Arg Thr Gly Phe Pro Asn Ile Ala Leu Ala Leu Gly Asp 835 840 845

get ttg cct cga gaa ale aUg aag eat ctc ctg get aaa gca get atg Ala Leu Pro Arg Glu Ile Met Lys Asn Leu Leu Asp Lys Ala Asp Met 850 855 860

cag tgg get aaa cta gct gaa let gaa ctt gga agt ttg tgg age ttg Gln Trp Asp Lys Leu Ala Glu Ser Glu Leu Gly Ser Leu Trp Arg Leu 865 870 875 880

gaa gga tat cta gag ace tgg tcc tgg agt tta aac gta cct gtc cta Glu Gly Ser Leu Glu Thr Trp Ser Trp Ser Leu Asn Val Pro Val Leu 885 890 895

agc agc ctt let gac gaa get gag gUg tta cat atg tcc gaa gag tat Ser Ser Leu Ser Asp Glu Asp Glu Val Leu Hls Met Ser Glu Glu Tyr 900 905 910

get aac gag gcg caa aaa tac aag gaa caa agg agc aaa att leg cgt Asp Asn Ala Ala Gln Lys Tyr Lys Glu Gln Arg Ser Lys Ile Ser Arg 915 920 925

ttg aag aag aag atg tcc cgg lea gaa ggg ttc age gaa tat aag aaa Leu Lys Lys Lys Met Ser Arg Ser Glu Gly Phe Arg Glu Tyr Lys Lys 930 935 940

-246 att cta gag aat gct aac ttg acg gtt gag aag atg aaa cgg ctc aag Ile Leu Glu Asn Ala Asn Leu Thr Val Glu Lys Met Lys Arg Leu Lys 945 950 955 960

gcg aga tcg aga cgc ctt ata aac cgt tta gag cag att gaa ccg tct Ala Arg Ser Arg Arg Leu Ile Asn Arg Leu Glu Gln Ile Glu Pro Ser 965 970 975

ggt tgg aaa gat ttc atg cgc ata agc aac gtg att cac gaa agc aga Gly Trp Lys Asp Phe Met Arg Ile Ser Asn Val Ile His Glu Ser Arg 980 985 990

gca ttg gac att aat aca cac ttg ata ttt cct ctg gga gaa aca gat Ala Leu Asp Ile Asn Thr His Leu Ile Phe Pro Leu Gly Glu Thr Ala 995 1000 1005

gct goa atc cga gga gaa aac gag ctt tgg ctt gca atg gtg ttg Ala Ala Ile Arg Gly Glu Asn Glu Leu Trp Leu Ala Met Val Leu 1010 1015 1020

cgg aac aaa gac ctg gtg gat ctc aag cct cct caa cta gct ggt Arg Asn Lys Ala Leu Val Asp Leu Lys Pro Pro Gln Leu Ala Gly 1025 1030 1035

gta tgt goa agt tta gtt tca gaa ggc ata aaa ght cga cct tgg Val Cys Ala Ser Leu Val Ser Glu Gly Ile Lys Val Arg Pro Trp 1040 1045 1050

aga gac aac aac tat att tac gag cca tat gat aca gta gLa gac Arg Asp Asn Asn Tyr Ile Tyr Glu Pro Ser Asp Thr Val Val Asp 1055 1060 1065

aLg gtc aat ttc tta gaa gac caa aga agc tct cUt ata aag ctt Met Val Asn Phe Leu Glu Asp Gln Arg Ser Ser Leu Ile Lys Leu 1070 1075 1080

caa gag aag cac gag gtt aLg att cca tgt tgt ctg gac ght cag Gln Glu Lys His Glu Val Met Ile Pro Cys Cys Leu Asp Val Gln 1085 1090 1095

-247 thc let ggt atg gtt gaa gct tgg gct let gga tta agt tgg aaa Phe Ser Gly Met Val Glu Ala Trp Ala Ser Gly Leu Ser Trp Lys 1100 1105 1110

gaa atg atg aLg gaa tgt gca atg gac gaa ggc get ctt gct cgc Glu Met Met Met Glu Cys Ala Met Asp Glu Gly Asp Leu Ala Arg 1115 1120 1125

ctg tta cga cgc ace att get ctc tta gct cag att cat aag ttg Leu Leu Arg Arg Thr Ile Asp Leu Leu Ala Gln Ile Pro Lys Leu 1130 1135 1140

cct get att gac cca gtc ctg caa cgt agt gca gca gct gca gca Pro Asp Ile Asp Pro Val Leu Gln Arg Ser Ala Ala Ala Ala Ala 1145 1150 1155

get ale atg gac cgt cca cca att agt gag ctt gcc ggt tea Asp Ile Met Asp Arg Pro Pro Ile Ser Glu Leu Ala Gly 1160 1165 1170

<210> 60

<211> 1171

<212> PRT

<213> Arabidopsis thaliana <400> 60

Met Asn Thr Leu Pro Val Val Ser Leu Thr Ala Ser Ser Ser Phe Lys 1 5 10 15

Phe Phe His Phe Pro Ser Leu His Arg Ser Leu Ser His Ser Pro Asn 20 25 30

Phe Ser Phe Thr Lys Ser Leu Ile Leu Asn Pro Asn His Leu Ser Phe 35 40 45

-248 Lys Ser Thr Leu Asn Ser Leu Ser Pro Ser Gln Ser Gln Leu Tyr Glu Glu Glu Asp Asp Glu Glu Glu Glu Glu Glu Asp Glu Asp Asp Asp Asp Glu Ala Ala Asp Glu Tyr Asp Asn Ile Ser Asp Glu Ile Arg Asn Ser 85 90 95

Asp Asp Asp Asp Asp Asp Glu Glu Thr Glu Phe Ser Val Asp Leu Pro 100 105 110

Thr Glu Ser Ala Arg Glu Arg Val Glu Phe Arg Trp Gln Arg Val Glu Lys Leu Arg Ser Leu Val Arg Asp Phe Gly Val Glu Met Ile Asp Ile Asp Glu Leu Ile Ser Ile Tyr Asp Phe Arg Ile Asp Lys Phe Gln Arg Leu Ala Ile Glu Ala Phe Leu Arg Gly Ser Ser Val Val Val Ser Ala Pro Thr Ser Ser Gly Lys Thr Leu Ile Ala Glu Ala Ala Ala Val Ser 180 185 190

Thr Val Ala Lys Gly Arg Arg Leu Phe Tyr Thr Thr Pro Leu Lys Ala 195 200 205

Leu Ser Asn Gln Lys Phe Arg Glu Phe Arg Glu Thr Phe Gly Asp Asp Asn Val Gly Leu Leu Thr Gly Asp Ser Asp Ile Asn Lys Asp Ala Gln Ile Val Ile Met Thr Thr Glu Ile Leu Arg Asn Met Leu Tyr Gln Ser 245 250 255

-249 Val Gly Met Ala Ser Ser Gly Thr Gly Leu Phe His Val Asp Ala Ile 260 265 270

Val Leu Asp Glu Val His Tyr Leu Ser Asp Ile Ser Arg Gly Thr Val 275 280 285

Trp Glu Glu Ile Val Ile Tyr Cys Pro Lys Glu Val Gln Leu Ile Cys 290 295 300

Leu Ser Ala Thr Val Ala Asn Pro Asp Glu Leu Ala Gly Trp Ile Gly 305 310 315 320

Glu Ile His Gly Lys Thr Glu Leu Val Thr Ser Thr Arg Arg Pro Val 325 330 335

Pro Leu Thr Trp Tyr Phe Ser Thr Lys His Ser Leu Leu Pro Leu Leu 340 345 350

Asp Glu Lys Gly Ile Asn Val Asn Arg Lys Leu Ser Leu Asn Tyr Leu 355 360 365

Gln Leu Ser Ala Ser Glu Ala Arg Phe Arg Asp Asp Asp Asp Gly Tyr 370 375 380

Arg Lys Arg Arg Ser Lys Lys Arg Gly Gly Asp Thr Ser Tyr Asn Asn 385 390 395 400

Leu Val Asn Val Thr Asp Tyr Pro Leu Ser Lys Asn Glu Ile Asn Lys 405 410 415

Ile Arg Arg Ser Gln Val Pro Gln Ile Ser Asp Thr Leu Trp His Leu 420 425 430

Gln Gly Lys Asn Met Leu Pro Ala Ile Trp Phe Ile Phe Asn Arg Arg 435 440 445

-250 Gly Cys Asp Ala Ala Val Gln Tyr Val Glu Asn Phe Gln Leu Leu Asp 450 455 460

Asp Cys Glu Lys Ser Glu Val Glu Leu Ala Leu Lys Lys Phe Arg Val 465 470 475 480

Leu Tyr Pro Asp Ala Val Arg Glu Ser Ala Glu Lys Gly Leu Leu Arg 485 490 495

Gly Ile Ala Ala His His Ala Gly Cys Leu Pro Leu Trp Lys Ser Phe 500 505 510

Ile Glu Glu Leu Phe Gln Arg Gly Leu Val Lys Val Val Phe Ala Thr 515 520 525

Glu Thr Leu Ala Ala Gly Ile Asn Met Pro Ala Arg Thr Ala Val Ile 530 535 540

Ser Ser Leu Ser Lys Lys Ala Gly Asn Glu Arg Ile Glu Leu Gly Pro 545 550 555 560

Asn Glu Leu Tyr Gln Met Ala Gly Arg Ala Gly Arg Arg Gly Ile Asp 565 570 575

Glu Lys Gly Tyr Thr Val Leu Val Gln Thr Ala Phe Glu Gly Ala Glu 580 585 590

Glu Cys Cys Lys Leu Val Phe Ala Gly Val Lys Pro Leu Val Ser Gln 595 600 605

Phe Thr Ala Ser Tyr Gly Met Val Leu Asn Leu Val Ala Gly Ser Lys 610 615 620

Val Thr Arg Lys Ser Ser Gly Thr Glu Ala Gly Lys Val Leu Gln Ala 625 630 635 640

Gly Arg Ser Leu Glu Glu Ala Lys Lys Leu Val Glu Lys Ser Phe Gly 645 650 655

-251 Asn Tyr Val Ser Ser Asn Val Thr Val Ala Ala Lys Gln Glu Leu Ala 660 665 670

Glu Ile Asp Asn Lys Ile Glu Ile Leu Ser Ser Glu Ile Ser Asp Glu 675 680 685

Ala Ile Asp Lys Lys Ser Arg Lys Leu Leu Ser Ala Arg Asp Tyr Lys 690 695 700

Glu Ile Thr Val Leu Lys Glu Glu Leu Arg Glu Glu Lys Arg Lys Arg 705 710 715 720

Ala Glu Gln Arg Arg Arg Met Glu Leu Glu Arg Phe Leu Ala Leu Lys 725 730 735

Pro Leu Leu Lys Gly Met Glu Glu Gly Asn Leu Pro Phe Ile Cys Leu 740 745 750

Glu Phe Lys Asp Ser Glu Gly Arg Glu Gln Ser Val Pro Ala Val Tyr 755 760 765

Leu Gly His Ile Asp Ser Phe Gln Gly Ser Lys Leu Gln Lys Met Met 770 775 780

Ser Leu Asp Glu Ser Phe Ala Leu Asn Leu Ile Glu Asp Glu Leu Ala 785 790 795 800

Ala Asp Glu Pro Gly Lys Pro Asn Val Lys Pro Ser Tyr Tyr Val Ala 805 810 815

Leu Gly Ser Asp Asn Ser Trp Tyr Leu Phe Thr Glu Lys Trp Val Arg 820 825 830

Thr Val Tyr Arg Thr Gly Phe Pro Asn Ile Ala Leu Ala Leu Gly Asp 835 840 845

-252 Ala Leu Pro Arg Glu Ile Met Lys Asn Leu Leu Asp Lys Ala Asp Met 850 855 860

Gln Trp Asp Lys Leu Ala Glu Ser Glu Leu Gly Ser Leu Trp Arg Leu 865 870 875 880

Glu Gly Ser Leu Glu Thr Trp Ser Trp Ser Leu Asn Val Pro Val Leu 885 890 895

Ser Ser Leu Ser Asp Glu Asp Glu Val Leu His Met Ser Glu Glu Tyr 900 905 910

Asp Asn Ala Ala Gln Lys Tyr Lys Glu Gln Arg Ser Lys Ile Ser Arg 915 920 925

Leu Lys Lys Lys Met Ser Arg Ser Glu Gly Phe Arg Glu Tyr Lys Lys 930 935 940

Ile Leu Glu Asn Ala Asn Leu Thr Val Glu Lys Met Lys Arg Leu Lys 945 950 955 960

Ala Arg Ser Arg Arg Leu Ile Asn Arg Leu Glu Gln Ile Glu Pro Ser 965 970 975

Gly Trp Lys Asp Phe Met Arg Ile Ser Asn Val Ile His Glu Ser Arg 980 985 990

Ala Leu Asp Ile Asn Thr His Leu Ile Phe Pro Leu Gly Glu Thr Ala 995 1000 1005

Ala Ala Ile Arg Gly Glu Asn Glu Leu Trp Leu Ala Met Val Leu 1010 1015 1020

Arg Asn Lys Ala Leu Val Asp Leu Lys Pro Pro Gln Leu Ala Gly 1025 1030 1035

Val Cys Ala Ser Leu Val Ser Glu Gly Ile Lys Val Arg Pro Trp 1040 1045 1050

-253 Arg Asp Asn Asn Tyr Ile Tyr Glu Pro Ser Asp Thr Val Val Asp 1055 1060 1065

Met Val Asn Phe Leu Glu Asp Gln Arg Ser Ser Leu Ile Lys Leu 1070 1075 1080

Gln Glu Lys His Glu Val Met Ile Pro Cys Cys Leu Asp Val Gln 1085 1090 1095

Phe Ser Gly Met Val Glu Ala Trp Ala Ser Gly Leu Ser Trp Lys 1100 1105 1110

Glu Met Met Met Glu Cys Ala Met Asp Glu Gly Asp Leu Ala Arg 1115 1120 1125

Leu Leu Arg Arg Thr Ile Asp Leu Leu Ala Gln Ile Pro Lys Leu 1130 1135 1140

Pro Asp Ile Asp Pro Val Leu Gln Arg Ser Ala Ala Ala Ala Ala 1145 1150 1155

Asp Ile Met Asp Arg Pro Pro Ile Ser Glu Leu Ala Gly 1160 1165 1170

<210> 61

<211> 2277

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1) (2277)

-254 <223> <400> 61

aLg ale ttt aaa ale gaa gac gta act gtc tac ttc cct tat gac aac Met Ile Phe Lys Ile Glu Asp Val Thr Val Tyr Phe Pro Tyr Asp Asn 1 5 10 15

ata tat cca gaa caa tat gaa tac aUg gtt gaa ttg aag cga gac cta Ile Tyr Pro Glu Gln Tyr Glu Tyr Met Val Glu Leu Lys Arg Ala Leu 20 25 30

gac gct aag gga cat tgt ctt ctc gag atg cct acc gga act ggt aaa Asp Ala Lys Gly His Cys Leu Leu Glu Met Pro Thr Gly Thr Gly Lys 35 40 45

acc att gct ctt ctc let cta ale acc agc tat cga ctc let cgt cct Thr Ile Ala Leu Leu Ser Leu Ile Thr Ser Tyr Arg Leu Ser Arg Pro 50 55 60

get let ccg ale aag ctt gtt tac tgt act cgt act gtc cac gag aLg Asp Ser Pro Ile Lys Leu Val Tyr Cys Thr Arg Thr Val His Glu Met 65 70 75 80

gag aaa acg tta ggt gag ctt aag cta cta cat gac tac caa gta cgc Glu Lys Thr Leu Gly Glu Leu Lys Leu Leu His Asp Tyr Gln Val Arg 85 90 95

cat ctc ggc acc cag get aag ale ctc gac ctt ggt ctt tcc tat cgg His Leu Gly Thr Gln Ala Lys Ile Leu Ala Leu Gly Leu Ser Ser Arg 100 105 110

aag eat cUt tgc gEt eat act aag gtt tta goa gcc gag eat cgt get Lys Asn Leu Cys Val Asn Thr Lys Val Leu Ala Ala Glu Asn Arg Asp 115 120 125

tat gtt get gag gcc tgt agg aaa cga act get agc tgg gtt agg gct Ser Val Asp Ala Ala Cys Arg Lys Arg Thr Ala Ser Trp Val Arg Ala 130 135 140

-255 ttg tcc acg gag aat cca aat gta gaa ctc tgt gac ttc tUt gag aac Leu Ser Thr Glu Asn Pro Asn Val Glu Leu Cys Asp Phe Phe Glu Asn 145 150 155 160

tat gaa aag gct gat gag aat gcg ttg ttg cct cct ggt gtt tat act Tyr Glu Lys Ala Ala Glu Asn Ala Leu Leu Pro Pro Gly Val Tyr Thr 165 170 175 tta gag gat cta agg gcg tUt ggt aag aat cgt gga tgg tgc cct tac Leu Glu

Asp Leu Arg Ala Phe Gly Lys Asn Arg Gly Trp Cys Pro Tyr 180 185 190

ttt ctc gag agg cat atg att cag tUc gcc aac gtt att gtt tac agc Phe Leu Ala Arg His Met Ile Gln Phe Ala Asn Val Ile Val Tyr Ser 195 200 205

tac caa tac cta ctg gat cct aag gtt gct ggg ttc ata tca aag gag Tyr Gln Tyr Leu Leu Asp Pro Lys Val Ala Gly Phe Ile Ser Lys Glu 210 215 220

tta caa aaa gag tca gtt gLa gtg ttt gac gag gcc cat aat atc gat Leu Gln Lys Glu Ser Val Val Val Phe Asp Glu Ala His Asn Ile Asp 225 230 235 240

aac gtg tgt att gaa gca ctc agc gtc agt gtg agg agg gtt aca ctt Asn Val Cys Ile Glu Ala Leu Ser Val Ser Val Arg Arg Val Thr Leu 245 250 255

gaa gga gct aat cga aat ctt aat aag ata agg caa gaa att gat agg Glu Gly Ala Asn Arg Asn Leu Asn Lys Ile Arg Gln Glu Ile Asp Arg 260 265 270

thc aag gat act gat gca gga aga ttg cgr gct gaa tac aac cgg ctg Phe Lys Ala Thr Asp Ala Gly Arg Leu Arg Ala Glu Tyr Asn Arg Leu 275 280 285

gtt gag ggt tta gca ctg aga ggg gac tta tct gga ggt gat caa tgg Val Glu Gly Leu Ala Leu Arg Gly Asp Leu Ser Gly Gly Asp Gln Trp 290 295 300

-256 ctt gca aac cct gca ctg cct cat get att cta aag gag gct gtc ccg Leu Ala Asn Pro Ala Leu Pro His Asp Ile Leu Lys Glu Ala Val Pro 305 310 315 320

ggg eat att age cgg gct gag cat ttt gtg cat gtt tta cgc cga tta Gly Asn Ile Arg Arg Ala Glu His Phe Val His Val Leu Arg Arg Leu 325 330 335

cUt cag tac ttg ggg gta cgg ctg gac act gag eat gta gag aaa gaa Leu Gln Tyr Leu Gly Val Arg Leu Asp Thr Glu Asn Val Glu Lys Glu 340 345 350

agc cat gtt agc ttt gta leg lea ctg eat tat cag gct gga att gag Ser Pro Val Ser Phe Val Ser Ser Leu Asn Ser Gln Ala Gly Ile Glu 355 360 365

cag aaa ace chg aag tUc tgt tat gac cgg ctc cag let ctc atg cta Gln Lys Thr Leu Lys Phe Cys Tyr Asp Arg Leu Gln Ser Leu Met Leu 370 375 380

acc ctt gaa att ace get ace get gag ttt ttg cct ale cag ace gtg Thr Leu Glu Ile Thr Asp Thr Asp Glu Phe Leu Pro Ile Gln Thr Val 385 390 395 400

tgc gac ttt gca act ctt gtt ggg ace tat gac cgg gga ttt tcc ale Cys Asp Phe Ala Thr Leu Val Gly Thr Tyr Ala Arg Gly Phe Ser Ile 405 410 415

ale ale gag cct tat gac gag age aLg ccc cat att cca get cct ata Ile Ile Glu Pro Tyr Asp Glu Arg Met Pro His Ile Pro Asp Pro Ile 420 425 430

ttg cag ttg agc tgt cat get gag tat chg gcg ale aaa ccg gtg ttt Leu Gln Leu Ser Cys His Asp Ala Ser Leu Ala Ile Lys Pro Val Phe 435 440 445

get cgt ttc cag lea gtc gtg att ace lea ggc ace ttg agc cca att Asp Arg Phe Gln Ser Val Val Ile Thr Ser Gly Thr Leu Ser Pro Ile 450 455 460

-257 gat ctt tac ccc cgt ctt ctt aat ttc act cct gtt gtt agt cga agc Asp Leu Tyr Pro Arg Leu Leu Asn Phe Thr Pro Val Val Ser Arg Ser 465 470 475 480

ttt aag atg tca atg aca cga gac tgc atc tgc cct atg gtt cta act Phe Lys Met Ser Met Thr Arg Asp Cys Ile Cys Pro Met Val Leu Thr 485 490 495

cgg gga agt gat cag ctt cct gtt agc acc aaa ttt gac atg aga agt Arg Gly Ser Asp Gln Leu Pro Val Ser Thr Lys Phe Asp Met Arg Ser 500 505 510

gat cct ggt gtt gtg agg aat tac gga aag ctt ttg gta gag atg gta Asp Pro Gly Val Val Arg Asn Tyr Gly Lys Leu Leu Val Glu Met Val 515 520 525

tct att gtt cct gat gga gUt gtc tgc ttc tUt gUt agy tac tca tat Ser Ile Val Pro Asp Gly Val Val Cys Phe Phe Val Xaa Tyr Ser Tyr 530 535 540

atg gat ggc att att gct aca tgg aat gaa act gga att chg aag gaa Met Asp Gly Ile Ile Ala Thr Trp Asn Glu Thr Gly Ile Leu Lys Glu 545 550 555 560

ata atg caa cag aag cUt gtt ttc att gaa aca caa gat gtt gta gaa Ile Met Gln Gln Lys Leu Val Phe Ile Glu Thr Gln Asp Val Val Glu 565 570 575

aca aca ttg gca ctg gat aat tat cgc agg gct tgc gat tgc gga aga Thr Thr Leu Ala Leu Asp Asn Tyr Arg Arg Ala Cys Asp Cys Gly Arg 580 585 590

ggt gca gtt thc ttc tat gtg gac agg ggg aaa gUt gat gaa ggt atc Gly Ala Val Phe Phe Ser Val Ala Arg Gly Lys Val Ala Glu Gly Ile 595 600 605

gat tEt gat cgt cat tat gga aga ctg gtt gta aLg tac gga gta cca Asp Phe Asp Arg His Tyr Gly Arg Leu Val Val Met Tyr Gly Val Pro 610 615 620

-258 ttc cag tat ace tta agc aag ata tta cga gca age ttg gag tat ttg Phe Gln Tyr Thr Leu Ser Lys Ile Leu Arg Ala Arg Leu Glu Tyr Leu 625 630 635 640

cac get ace ttt caa ata aaa gaa ggc get tUc cta act ttt get gcc His Asp Thr Phe Gln Ile Lys Glu Gly Asp Phe Leu Thr Phe Asp Ala 645 650 655

ttg agg caa gca gct caa tgt gta ggg cga gta ale cgg lea aag gct Leu Arg Gln Ala Ala Gln Cys Val Gly Arg Val Ile Arg Ser Lys Ala 660 665 670

get tat ggg aLg aLg ata tUt gca gac aaa age tac agc cgt cat get Asp Tyr Gly Met Met Ile Phe Ala Asp Lys Arg Tyr Ser Arg His Asp 675 680 685

aag cgg tcc aaa cta cct ggt tgg ata ctt leg cat ctg cgt get gca Lys Arg Ser Lys Leu Pro Gly Trp Ile Leu Ser His Leu Arg Asp Ala 690 695 700

cac ttg eat cta agc act get atg gct att cac att gct cga gag ttt His Leu Asn Leu Ser Thr Asp Met Ala Ile His Ile Ala Arg Glu Phe 705 710 715 720

cht cgg aaa atg gct caa ccg tat get aag gcg ggt ace atg gga agg Leu Arg Lys Met Ala Gln Pro Tyr Asp Lys Ala Gly Thr Met Gly Arg 725 730 735

aaa act chg ttg ace caa gaa get ttg gag aag atg get gag act ggt Lys Thr Leu Leu Thr Gln Glu Asp Leu Glu Lys Met Ala Glu Thr Gly 740 745 750

gtg caa gac atg gct tat tag Val Gln Asp Met Ala Tyr <210> 62

<211> 758

-259 <212> PRT

<213> Arabidopsis thaliana <220> <221> misc feature <222> (541)..(541)

<223> The 'Xaa' at location 541 stands for Ser.

<400> 62

Met Ile Phe Lys Ile Glu Asp Val Thr Val Tyr Phe Pro Tyr Asp Asn 1 5 10 15

Ile Tyr Pro Glu Gln Tyr Glu Tyr Met Val Glu Leu Lys Arg Ala Leu 20 25 30

Asp Ala Lys Gly His Cys Leu Leu Glu Met Pro Thr Gly Thr Gly Lys 35 40 45

Thr Ile Ala Leu Leu Ser Leu Ile Thr Ser Tyr Arg Leu Ser Arg Pro 50 55 60

Asp Ser Pro Ile Lys Leu Val Tyr Cys Thr Arg Thr Val His Glu Met 65 70 75 80

Glu Lys Thr Leu Gly Glu Leu Lys Leu Leu His Asp Tyr Gln Val Arg 85 90 95

His Leu Gly Thr Gln Ala Lys Ile Leu Ala Leu Gly Leu Ser Ser Arg 100 105 110

Lys Asn Leu Cys Val Asn Thr Lys Val Leu Ala Ala Glu Asn Arg Asp 115 120 125

Ser Val Asp Ala Ala Cys Arg Lys Arg Thr Ala Ser Trp Val Arg Ala 130 135 140

-260 Leu Ser Thr Glu Asn Pro Asn Val Glu Leu Cys Asp Phe Phe Glu Asn 145 150 155 160

Tyr Glu Lys Ala Ala Glu Asn Ala Leu Leu Pro Pro Gly Val Tyr Thr 165 170 175

Leu Glu Asp Leu Arg Ala Phe Gly Lys Asn Arg Gly Trp Cys Pro Tyr Phe Leu Ala Arg His Met Ile Gln Phe Ala Asn Val Ile Val Tyr Ser 195 200 205

Tyr Gln Tyr Leu Leu Asp Pro Lys Val Ala Gly Phe Ile Ser Lys Glu 210 215 220

Leu Gln Lys Glu Ser Val Val Val Phe Asp Glu Ala His Asn Ile Asp 225 230 235 240

Asn Val Cys Ile Glu Ala Leu Ser Val Ser Val Arg Arg Val Thr Leu 245 250 255

Glu Gly Ala Asn Arg Asn Leu Asn Lys Ile Arg Gln Glu Ile Asp Arg 260 265 270

Phe Lys Ala Thr Asp Ala Gly Arg Leu Arg Ala Glu Tyr Asn Arg Leu 275 280 285

Val Glu Gly Leu Ala Leu Arg Gly Asp Leu Ser Gly Gly Asp Gln Trp 290 295 300

Leu Ala Asn Pro Ala Leu Pro His Asp Ile Leu Lys Glu Ala Val Pro 305 310 315 320

Gly Asn Ile Arg Arg Ala Glu His Phe Val His Val Leu Arg Arg Leu 325 330 335

-261 Leu Gln Tyr Leu Gly Val Arg Leu Asp Thr Glu Asn Val Glu Lys Glu 340 345 350

Ser Pro Val Ser Phe Val Ser Ser Leu Asn Ser Gln Ala Gly Ile Glu 355 360 365

Gln Lys Thr Leu Lys Phe Cys Tyr Asp Arg Leu Gln Ser Leu Met Leu 370 375 380

Thr Leu Glu Ile Thr Asp Thr Asp Glu Phe Leu Pro Ile Gln Thr Val 385 390 395 400

Cys Asp Phe Ala Thr Leu Val Gly Thr Tyr Ala Arg Gly Phe Ser Ile 405 410 415

Ile Ile Glu Pro Tyr Asp Glu Arg Met Pro His Ile Pro Asp Pro Ile 420 425 430

Leu Gln Leu Ser Cys His Asp Ala Ser Leu Ala Ile Lys Pro Val Phe 435 440 445

* Asp Arg Phe Gln Ser Val Val Ile Thr Ser Gly Thr Leu Ser Pro Ile 450 455 460

Asp Leu Tyr Pro Arg Leu Leu Asn Phe Thr Pro Val Val Ser Arg Ser 465 470 475 480

Phe Lys Met Ser Met Thr Arg Asp Cys Ile Cys Pro Met Val Leu Thr 485 490 495

Arg Gly Ser Asp Gln Leu Pro Val Ser Thr Lys Phe Asp Met Arg Ser 500 505 510

Asp Pro Gly Val Val Arg Asn Tyr Gly Lys Leu Leu Val Glu Met Val 515 520 525

Ser Ile Val Pro Asp Gly Val Val Cys Phe Phe Val Xaa Tyr Ser Tyr 530 535 540

-262 Met Asp Gly Ile Ile Ala Thr Trp Asn Glu Thr Gly Ile Leu Lys Glu 545 550 555 560

Ile Met Gln Gln Lys Leu Val Phe Ile Glu Thr Gln Asp Val Val Glu 565 570 575

Thr Thr Leu Ala Leu Asp Asn Tyr Arg Arg Ala Cys Asp Cys Gly Arg 580 585 590

Gly Ala Val Phe Phe Ser Val Ala Arg Gly Lys Val Ala Glu Gly Ile 595 600 605

Asp Phe Asp Arg His Tyr Gly Arg Leu Val Val Met Tyr Gly Val Pro 610 615 620

Phe Gln Tyr Thr Leu Ser Lys Ile Leu Arg Ala Arg Leu Glu Tyr Leu 625 630 635 640

His Asp Thr Phe Gln Ile Lys Glu Gly Asp Phe Leu Thr Phe Asp Ala 645 650 655

Leu Arg Gln Ala Ala Gln Cys Val Gly Arg Val Ile Arg Ser Lys Ala 660 665 670

Asp Tyr Gly Met Met Ile Phe Ala Asp Lys Arg Tyr Ser Arg His Asp 675 680 685

Lys Arg Ser Lys Leu Pro Gly Trp Ile Leu Ser His Leu Arg Asp Ala 690 695 700

His Leu Asn Leu Ser Thr Asp Met Ala Ile His Ile Ala Arg Glu Phe 705 710 715 720

Leu Arg Lys Met Ala Gln Pro Tyr Asp Lys Ala Gly Thr Met Gly Arg 725 730 735

-263 Lys Thr Leu Leu Thr Gln Glu Asp Leu Glu Lys Met Ala Glu Thr Gly 740 745 750

Val Gln Asp Met Ala Tyr <210> 63

<211> 1032

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1032)

<223> <400> 63

atg gag agg tac gaa ata gtg aag get att ggg let ggt aac ttc gga Met Glu Arg Tyr Glu Ile Val Lys Asp Ile Gly Ser Gly Asn Phe Gly 1 5 10 15

gta goa aag cht gtt cgt gac aaa tEt tcc aaa gag ctt ttc get gtt Val Ala Lys Leu Val Arg Asp Lys Phe Ser Lys Glu Leu Phe Ala Val 20 25 30

aag tEc ale gag cga ggc caa aag att get gaa cat gta caa age gaa Lys Phe Ile Glu Arg Gly Gln Lys Ile Asp Glu His Val Gln Arg Glu 35 40 45

ale atg aac cat agg leg ctg ale cat cac eat ata ata age ttc aag Ile Met Asn His Arg Ser Leu Ile His Pro Asn Ile Ile Arg Phe Lys 50 55 60

-264 gag gtt tta ttg aeg goa ace cat ttg gcg tta gta atg gaa tac gcc Glu Val Leu Leu Thr Ala Thr His Leu Ala Leu Val Met Glu Tyr Ala 65 70 75 80

gcc gga gga gaa ctg ttc gga age ale tgc agc gcc gga age tUc agt Ala Gly Gly Glu Leu Phe Gly Arg Ile Cys Ser Ala Gly Arg Phe Ser 85 90 95

gaa gac gag gca agg ttt ttc ttt cag cag ctt ata lea gga gtt eat Glu Asp Glu Ala Arg Phe Phe Phe Gln Gln Leu Ile Ser Gly Val Asn 100 105 110

tac tgt cac agt ctt caa ata tgc cat age get tta aag cta gag aac Tyr Cys His Ser Leu Gln Ile Cys His Arg Asp Leu Lys Leu Glu Asn 115 120 125

aeg tta ctt get gga agc gaa gcg cca cgt gta aag att tgc gac ttt Thr Leu Leu Asp Gly Ser Glu Ala Pro Arg Val Lys Ile Cys Asp Phe 130 135 140

gga tat lea aaa lea gga gtt ctt cat leg caa cca aag ace ace gta Gly Tyr Ser Lys Ser Gly Val Leu His Ser Gln Pro Lys Thr Thr Val 145 150 155 160

gga ace cat gct tac att goa cct gaa gtg ctc tcc acg aaa gag tat Gly Thr Pro Ala Tyr Ile Ala Pro Glu Val Leu Ser Thr Lys Glu Tyr 165 170 175

gac ggc aaa ale gct get gtt tgg let tgt gga gtc act ttg tat gtt Asp Gly Lys Ile Ala Asp Val Trp Ser Cys Gly Val Thr Leu Tyr Val 180 185 190

atg ctt gEt ggt gct tat cat tUt gaa get cat let get cct aaa get Met Leu Val Gly Ala Tyr Pro Phe Glu Asp Pro Ser Asp Pro Lys Asp 195 200 205

ttt cgg aag acg ale ggt cgg att ctc aaa get cag tat get att cat Phe Arg Lys Thr Ile Gly Arg Ile Leu Lys Ala Gln Tyr Ala Ile Pro 210 215 220

-265 gat tat gtt cga gtt leg get gaa tgc age cat ctt ctc tat cgg ata Asp Tyr Val Arg Val Ser Asp Glu Cys Arg His Leu Leu Ser Arg Ile 225 230 235 240

ttc gtt gcc aac cct gaa aag age ata ace ata gag gag ata aag eat Phe Val Ala Asn Pro Glu Lys Arg Ile Thr Ile Glu Glu Ile Lys Asn 245 250 255

cat let tgg ttt ctc aag aac ttg ccg gta gag atg tat gaa gga lea His Ser Trp Phe Leu Lys Asn Leu Pro Val Glu Met Tyr Glu Gly Ser 260 265 270

ttg atg atg eat ggt cca leg act cag ace gta gaa gag ata gtg tgg Leu Met Met Asn Gly Pro Ser Thr Gln Thr Val Glu Glu Ile Val Trp 275 280 285

ale att gaa gaa get cgg aaa cat ale acc gta gct act gga ctc gca Ile Ile Glu Glu Ala Arg Lys Pro Ile Thr Val Ala Thr Gly Leu Ala 290 295 300

ggt gct ggt ggc let ggt gga agc agt eat ggt gcc att gga agt agc Gly Ala Gly Gly Ser Gly Gly Ser Ser Asn Gly Ala Ile Gly Ser Ser 305 310 315 320

agt atg get ctc get gac ttg gac ace get ttc gac gac ale get acc Ser Met Asp Leu Asp Asp Leu Asp Thr Asp Phe Asp Asp Ile Asp Thr 325 330 335

gct get ctc ctt tcc cat ttg tga Ala Asp Leu Leu Ser Pro Leu <210> 64

<211> 343

<212> PRT

<213> Arabidopsis thaliana

-266 <400> 64

Met Glu Arg Tyr Glu Ile Val Lys Asp Ile Gly Ser Gly Asn Phe Gly 1 5 10 15

Val Ala Lys Leu Val Arg Asp Lys Phe Ser Lys Glu Leu Phe Ala Val 20 25 30

Lys Phe Ile Glu Arg Gly Gln Lys Ile Asp Glu His Val Gln Arg Glu 35 40 45

Ile Met Asn His Arg Ser Leu Ile His Pro Asn Ile Ile Arg Phe Lys 50 55 60

Glu Val Leu Leu Thr Ala Thr His Leu Ala Leu Val Met Glu Tyr Ala 65 70 75 80

Ala Gly Gly Glu Leu Phe Gly Arg Ile Cys Ser Ala Gly Arg Phe Ser 85 90 95

Glu Asp Glu Ala Arg Phe Phe Phe Gln Gln Leu Ile Ser Gly Val Asn 100 105 110

Tyr Cys His Ser Leu Gln Ile Cys His Arg Asp Leu Lys Leu Glu Asn 115 120 125

Thr Leu Leu Asp Gly Ser Glu Ala Pro Arg Val Lys Ile Cys Asp Phe 130 135 140

Gly Tyr Ser Lys Ser Gly Val Leu His Ser Gln Pro Lys Thr Thr Val 145 150 155 160

Gly Thr Pro Ala Tyr Ile Ala Pro Glu Val Leu Ser Thr Lys Glu Tyr 165 170 175

Asp Gly Lys Ile Ala Asp Val Trp Ser Cys Gly Val Thr Leu Tyr Val 180 185 190

-267 Met Leu Val Gly Ala Tyr Pro Phe Glu Asp Pro Ser Asp Pro Lys Asp 195 200 205

Phe Arg Lys Thr Ile Gly Arg Ile Leu Lys Ala Gln Tyr Ala Ile Pro 210 215 220

Asp Tyr Val Arg Val Ser Asp Glu Cys Arg His Leu Leu Ser Arg Ile 225 230 235 240

Phe Val Ala Asn Pro Glu Lys Arg Ile Thr Ile Glu Glu Ile Lys Asn 245 250 255

His Ser Trp Phe Leu Lys Asn Leu Pro Val Glu Met Tyr Glu Gly Ser 260 265 270

Leu Met Met Asn Gly Pro Ser Thr Gln Thr Val Glu Glu Ile Val Trp 275 280 285

Ile Ile Glu Glu Ala Arg Lys Pro Ile Thr Val Ala Thr Gly Leu Ala 290 295 300

Gly Ala Gly Gly Ser Gly Gly Ser Ser Asn Gly Ala Ile Gly Ser Ser 305 310 315 320

Ser Met Asp Leu Asp Asp Leu Asp Thr Asp Phe Asp Asp Ile Asp Thr 325 330 335

Ala Asp Leu Leu Ser Pro Leu <210> 65

<211> 1146

<212> DNA

<213> Arabidopsis thaliana

-268 <220> <221> CDS

<222> (1)..(1146)

<223> <400> 65

atg gcg ggt ttc agt let cta att cct age acg ctt ctg aaa cgc gac Met Ala Gly Phe Ser Ser Leu Ile Pro Arg Thr Leu Leu Lys Arg Ala 1 5 10 15

gtt agt agc gca ace age eat cta acg gcg ccg tta gct let att lea Val Ser Ser Ala Thr Arg Asn Leu Thr Ala Pro Leu Ala Ser Ile Ser 20 25 30

gca gca age eat ctc ttc att gga gga gga tgt gac gaa eat tat ggt Ala Ala Arg Asn Leu Phe Ile Gly Gly Gly Cys Asp Glu Asn Tyr Gly 35 40 45

gag cca gga gtg tht let cat tcc eat gga ata age aag tac aac acc Glu Pro Gly Val Phe Ser His Ser Asn Gly Ile Arg Lys Tyr Asn Thr 50 55 60

ght ggt eat get ggc gca cta act ggt cca ttt cat cat ctt ctt ggg Val Gly Asn Ala Gly Ala Leu Thr Gly Pro Phe His His Leu Leu Gly 65 70 75 80

gtc aac cag ace aac aag cac gcc ttt tta agg gtc caa tat atg agc Val Asn Gln Thr Asn Lys Pro Ala Phe Leu Arg Val Gln Ser Met Ser 85 90 95

tat cag ttt gtc get get tat cat lea tat cct aaa cgt att gtg aag Tyr Gln Phe Val Ala Asp Ser His Ser Ser Pro Lys Arg Ile Val Lys 100 105 110

eat gag get gag gaa get tEt tat get lea lea aag aag gga aac gct

-269 Asn Glu Asp Glu Glu Asp Phe Ser Asp Ser Ser Lys Lys Gly Asn Ala 115 120 125

gaa aac cct agg aaa cat caa att ggg gag aac ata ccc aag aag get Glu Asn Pro Arg Lys His Gln Ile Gly Glu Asn Ile Pro Lys Lys Asp 130 135 140

aaa ata aag ttt ctt gtg aac act ctt ctt get att gaa get eat aaa Lys Ile Lys Phe Leu Val Asn Thr Leu Leu Asp Ile Glu Asp Asn Lys 145 150 155 160

gag gct gtt tat gga gct ctg get gct tgg gtt gct tgg gag cgc eat Glu Ala Val Tyr Gly Ala Leu Asp Ala Trp Val Ala Trp Glu Arg Asn 165 170 175

ttc ccc att get tcc ctc aaa ata gta ata gct agt ctt gaa aag gaa Phe Pro Ile Ala Ser Leu Lys Ile Val Ile Ala Ser Leu Glu Lys Glu 180 185 190

cat caa tgg cat cga atg gtc cag gUg ata aag tgg ale cta agt aag His Gln Trp His Arg Met Val Gln Val Ile Lys Trp Ile Leu Ser Lys 195 200 205

gga caa ggg aac aeg atg ggg acg tac gga cag ttg ata cgg gcg tta Gly Gln Gly Asn Thr Met Gly Thr Tyr Gly Gln Leu Ile Arg Ala Leu 210 215 220

get aUg get cgt age gca gaa gag gct cat gtt ale tgg cga aag aaa Asp Met Asp Arg Arg Ala Glu Glu Ala His Val Ile Trp Arg Lys Lys 225 230 235 240

gtt ggg aac get ctg cat let gtg cct tgg caa tta tgc tta caa aUg Val Gly Asn Asp Leu His Ser Val Pro Trp Gln Leu Cys Leu Gln Met 245 250 255

aLg cgc ata tat ttc cgg aac aac atg tta cag gaa ctt gtt aag cta Met Arg Ile Tyr Phe Arg Asn Asn Met Leu Gln Glu Leu Val Lys Leu 260 265 270

ttc aag get ctg gag agt tat gac cgt aag cat ccg gac aag cac att

-270 Phe Lys Asp Leu Glu Ser Tyr Asp Arg Lys Pro Pro Asp Lys His Ile 275 280 285

gtg cag acc gtg gct get gct tat gag ctt ttg gga atg ctt get gag Val Gln Thr Val Ala Asp Ala Tyr Glu Leu Leu Gly Met Leu Asp Glu 290 295 300

aaa gaa cgg gta gtg acg aag tat agc cat ctt tta cht ggt ace cca Lys Glu Arg Val Val Thr Lys Tyr Ser His Leu Leu Leu Gly Thr Pro 305 310 315 320

tcc get get aaa cca agt age let leg agg aag aag aag aaa cca gaa Ser Asp Asp Lys Pro Ser Arg Ser Ser Arg Lys Lys Lys Lys Pro Glu 325 330 335

ctg agg att cca gaa gca acg ace gaa ggc goa gtt get gca gca aaa Leu Arg Ile Pro Glu Ala Thr Thr Glu Gly Ala Val Asp Ala Ala Lys 340 345 350

get gaa ale caa gaa gag cga aaa gaa eat ctg get eat cac caa gaa Ala Glu Ile Gln Glu Glu Arg Lys Glu Asn Leu Asp Asn His Gln Glu 355 360 365

lea gaa gct gcc act gaa aaa caa ttc gaa cat gga gcg tea Ser Glu Ala Ala Thr Glu Lys Gln Phe Glu His Gly Ala 370 375 380

<210> 66

<211> 381

<212> PRT

<213> Arabidopsis thaliana <400> 66

Met Ala Gly Phe Ser Ser Leu Ile Pro Arg Thr Leu Leu Lys Arg Ala 1 5 10 15

-271 Val Ser Ser Ala Thr Arg Asn Leu Thr Ala Pro Leu Ala Ser Ile Ser 20 25 30

Ala Ala Arg Asn Leu Phe Ile Gly Gly Gly Cys Asp Glu Asn Tyr Gly 35 40 45

Glu Pro Gly Val Phe Ser His Ser Asn Gly Ile Arg Lys Tyr Asn Thr 50 55 60

Val Gly Asn Ala Gly Ala Leu Thr Gly Pro Phe His His Leu Leu Gly 65 70 75 80

Val Asn Gln Thr Asn Lys Pro Ala Phe Leu Arg Val Gln Ser Met Ser 85 90 95

Tyr Gln Phe Val Ala Asp Ser His Ser Ser Pro Lys Arg Ile Val Lys 100 105 110

Asn Glu Asp Glu Glu Asp Phe Ser Asp Ser Ser Lys Lys Gly Asn Ala 115 120 125

Glu Asn Pro Arg Lys His Gln Ile Gly Glu Asn Ile Pro Lys Lys Asp 130 135 140

Lys Ile Lys Phe Leu Val Asn Thr Leu Leu Asp Ile Glu Asp Asn Lys 145 150 155 160

Glu Ala Val Tyr Gly Ala Leu Asp Ala Trp Val Ala Trp Glu Arg Asn 165 170 175

Phe Pro Ile Ala Ser Leu Lys Ile Val Ile Ala Ser Leu Glu Lys Glu 180 185 190

His Gln Trp His Arg Met Val Gln Val Ile Lys Trp Ile Leu Ser Lys 195 200 205

Gly Gln Gly Asn Thr Met Gly Thr Tyr Gly Gln Leu Ile Arg Ala Leu 210 215 220

-272 Asp Met Asp Arg Arg Ala Glu Glu Ala His Val Ile Trp Arg Lys Lys 225 230 235 240

Val Gly Asn Asp Leu His Ser Val Pro Trp Gln Leu Cys Leu Gln Met 245 250 255

Met Arg Ile Tyr Phe Arg Asn Asn Met Leu Gln Glu Leu Val Lys Leu 260 265 270

Phe Lys Asp Leu Glu Ser Tyr Asp Arg Lys Pro Pro Asp Lys His Ile 275 280 285

Val Gln Thr Val Ala Asp Ala Tyr Glu Leu Leu Gly Met Leu Asp Glu 290 295 300

Lys Glu Arg Val Val Thr Lys Tyr Ser His Leu Leu Leu Gly Thr Pro 305 310 315 320

Ser Asp Asp Lys Pro Ser Arg Ser Ser Arg Lys Lys Lys Lys Pro Glu 325 330 335

Leu Arg Ile Pro Glu Ala Thr Thr Glu Gly Ala Val Asp Ala Ala Lys 340 345 350

Ala Glu Ile Gln Glu Glu Arg Lys Glu Asn Leu Asp Asn His Gln Glu 355 360 365

Ser Glu Ala Ala Thr Glu Lys Gln Phe Glu His Gly Ala 370 375 380

<210> 67

<211> 2694

<212> DNA

<213> Arabidopsis thaliana

-273 <220> <221> CDS

<222> (1)..(2694)

<223> <400> 67

atg ggg get leg ctt cct cct aag gag gcc aac ctc ttc aag ctc ale Met Gly Ala Ser Leu Pro Pro Lys Glu Ala Asn Leu Phe Lys Leu Ile 1 5 10 15

gtc aaa lea tat gag act aag cag tac aag aag gga ctc aag gca gct Val Lys Ser Tyr Glu Thr Lys Gln Tyr Lys Lys Gly Leu Lys Ala Ala 20 25 30

get gcc ata tta aaa aag ttt cat get cat gga gag act tta leg atg Asp Ala Ile Leu Lys Lys Phe Pro Asp His Gly Glu Thr Leu Ser Met 35 40 45

aaa gga ctg act cta aac tgt atg gac cgc aaa act gaa goa tat gag Lys Gly Leu Thr Leu Asn Cys Met Asp Arg Lys Thr Glu Ala Tyr Glu 50 55 60

ctt ght cga ctt gga gtg aag eat get ale aaa agc cat gtt tgc tgg Leu Val Arg Leu Gly Val Lys Asn Asp Ile Lys Ser His Val Cys Trp 65 70 75 80

cat gtg ctt ggt ctt ttg tac cgg lea gac age gag tat age gaa goa His Val Leu Gly Leu Leu Tyr Arg Ser Asp Arg Glu Tyr Arg Glu Ala 85 90 95

ale aaa tgc tac cga eat gct ctt age ata get cat get aac ctt gaa Ile Lys Cys Tyr Arg Asn Ala Leu Arg Ile Asp Pro Asp Asn Leu Glu 100 105 110

ata ctc age gac ctc lea ctt ctg cag gca caa atg cgg gac tta tcc

-274 Ile Leu Arg Asp Leu Ser Leu Leu Gln Ala Gln Met Arg Asp Leu Ser 115 120 125

ggt ttt gtg gag acc agg cag cag ctt ttg ace ttg aag cct eat cac Gly Phe Val Glu Thr Arg Gln Gln Leu Leu Thr Leu Lys Pro Asn His 130 135 140

cga atg aac tgg att ggc tUt gca gtc let cag cat tta aac gca eat Arg Met Asn Trp Ile Gly Phe Ala Val Ser Gln His Leu Asn Ala Asn 145 150 155 160

gct let aaa gct gtt gaa att ttg gaa gcg tat gaa ggc acc tta gag Ala Ser Lys Ala Val Glu Ile Leu Glu Ala Tyr Glu Gly Thr Leu Glu 165 170 175

get gac tat cct cct gag aac gag cta att gaa cac ace gaa atg att Asp Asp Tyr Pro Pro Glu Asn Glu Leu Ile Glu His Thr Glu Met Ile 180 185 190

cta tac aag gtt tcc ttg ctt gag gag agt ggt let tht gac aaa gct Leu Tyr Lys Val Ser Leu Leu Glu Glu Ser Gly Ser Phe Asp Lys Ala 195 200 205

ctt gag gag ttg cac aaa aaa gag ccg aaa ata gtt get aag ttg tat Leu Glu Glu Leu His Lys Lys Glu Pro Lys Ile Val Asp Lys Leu Ser 210 215 220

tac aaa gaa caa gag gta tat ctc ttg lea aag gtt ggt cgt cta gaa Tyr Lys Glu Gln Glu Val Ser Leu Leu Ser Lys Val Gly Arg Leu Glu 225 230 235 240

gaa gcc eat aaa ctc tac agg gtt tta ctt tcc aLg aac cat gac eat Glu Ala Asn Lys Leu Tyr Arg Val Leu Leu Ser Met Asn Pro Asp Asn 245 250 255

tac age tat cat gag ggc ctc caa aaa tgc cUt gga ttg tat lea gaa Tyr Arg Tyr His Glu Gly Leu Gln Lys Cys Leu Gly Leu Tyr Ser Glu 260 265 270

agt ggt caa tat leg tcc gac cag att gaa aag tta eat get ttg tac

-275 Ser Gly Gln Tyr Ser Ser Asp Gln Ile Glu Lys Leu Asn Ala Leu Tyr 275 280 285

cag let cta agt gag cag tac act cgg lea tcc get gtt aag agg ata Gln Ser Leu Ser Glu Gln Tyr Thr Arg Ser Ser Ala Val Lys Arg Ile 290 295 300

cca ttg get tht ctg caa get gag aac ttt aag gag gct gLa gca aag Pro Leu Asp Phe Leu Gln Asp Glu Asn Phe Lys Glu Ala Val Ala Lys 305 310 315 320

tac att aaa cct cht ttg ace aag ggt gtt cat lea tta tUt let get Tyr Ile Lys Pro Leu Leu Thr Lys Gly Val Pro Ser Leu Phe Ser Asp 325 330 335

ctc tat let ctg tat get cac cat cgc aag cct get ata ttg gag caa Leu Ser Ser Leu Tyr Asp His Pro Arg Lys Pro Asp Ile Leu Glu Gln 340 345 350

cta gtt gtt gag atg aaa cat leg att ggg act ace gga agt ttc cca Leu Val Val Glu Met Lys His Ser Ile Gly Thr Thr Gly Ser Phe Pro 355 360 365

gga agt get gLa aaa gag ccc cct tat ace cta ttg tgg ace ttg ttt Gly Ser Asp Val Lys Glu Pro Pro Ser Thr Leu Leu Trp Thr Leu Phe 370 375 380

ttc ttg gct cag cat tat gac agg cgt ggt caa tat get gtt gcg ctc Phe Leu Ala Gln His Tyr Asp Arg Arg Gly Gln Tyr Asp Val Ala Leu 385 390 395 400

tgt aaa att get gag gcc att get cat acg cca ace gtg att get ctg Cys Lys Ile Asp Glu Ala Ile Ala His Thr Pro Thr Val Ile Asp Leu 405 410 415

tac tcc gEc aag agc cga ata atg aag cat gca gga gac ttg act gac Tyr Ser Val Lys Ser Arg Ile Met Lys His Ala Gly Asp Leu Thr Ala 420 425 430

get gct goa ctt gcc get gaa get age ggc atg gac cta gca get cgt

-276 Ala Ala Ala Leu Ala Asp Glu Ala Arg Gly Met Asp Leu Ala Asp Arg 435 440 445

tat ata aac agt gaa tgc gUt aag cgt atg tta caa goa get cag gtg Tyr Ile Asn Ser Glu Cys Val Lys Arg Met Leu Gln Ala Asp Gln Val 450 455 460

ccc ttg gct gag aaa act gct gtt tta tUt acc aaa gag ggg get cag Pro Leu Ala Glu Lys Thr Ala Val Leu Phe Thr Lys Glu Gly Asp Gln 465 470 475 480

ctc aac eat ctt cat gac atg cag tgc atg tgg tat get ctt gca let Leu Asn Asn Leu His Asp Met Gln Cys Met Trp Tyr Asp Leu Ala Ser 485 490 495

gga get agc tat ttc cgt cag ggt get ctt gga cgt gct ttg aag aag Gly Asp Ser Tyr Phe Arg Gln Gly Asp Leu Gly Arg Ala Leu Lys Lys 500 505 510

ttt ttg gct gUg gag aag cac tat gct gac att let gaa get caa ttt Phe Leu Ala Val Glu Lys His Tyr Ala Asp Ile Ser Glu Asp Gln Phe 515 520 525

get ttc cac leg tat tgt tta agg aaa atg act ttg cgt lea tat gUt Asp Phe His Ser Tyr Cys Leu Arg Lys Met Thr Leu Arg Ser Tyr Val 530 535 540

get aLg ctt aag tCc caa gac cga ttg cac lea tEc cca tat ttc cac Asp Met Leu Lys Phe Gln Asp Arg Leu His Ser Phe Pro Tyr Phe His 545 550 555 560

aaa goa gca ale age get ale age tgc tac ctg aaa ttg cat gac let Lys Ala Ala Ile Arg Ala Ile Arg Cys Tyr Leu Lys Leu His Asp Ser 565 570 575

cac aag lea act get gga gaa get gaa atg lea aag ttg gct cct gct Pro Lys Ser Thr Ala Gly Glu Asp Glu Met Ser Lys Leu Ala Pro Ala 580 585 590

cag aag aag aaa ale aag aag cag aaa aag gca gaa gcc cga gct aag

-277 Gln Lys Lys Lys Ile Lys Lys Gln Lys Lys Ala Glu Ala Arg Ala Lys 595 600 605

aaa gaa gct gag agt aag agt gaa gaa lea act gcc agt ggt gcc let Lys Glu Ala Glu Ser Lys Ser Glu Glu Ser Thr Ala Ser Gly Ala Ser 610 615 620

aag tat ggc aaa cga eat gtg aaa cct gta gac cca get cct cat ggg Lys Ser Gly Lys Arg Asn Val Lys Pro Val Asp Pro Asp Pro His Gly 625 630 635 640

caa aag tta att cag gtt gag gag cca atg gca gag gct lea aag tac Gln Lys Leu Ile Gln Val Glu Glu Pro Met Ala Glu Ala Ser Lys Tyr 645 650 655

ttg age cta ctc cag aaa cat lea cct eat let ttg gag act cat tta Leu Arg Leu Leu Gln Lys His Ser Pro Asn Ser Leu Glu Thr His Leu 660 665 670

ctt tcc ttt gag gtc eat atg age aaa cag aag ttt ctg ctt goa tCc Leu Ser Phe Glu Val Asn Met Arg Lys Gln Lys Phe Leu Leu Ala Phe 675 680 685

cag get gtc aag caa ttg ctt aaa ttg ggt gca gag aac cct get lea Gln Ala Val Lys Gln Leu Leu Lys Leu Gly Ala Glu Asn Pro Asp Ser 690 695 700

cat cgt tcc ttg gtt aaa tUc ttt ctc atg ace gaa tag ata agt gct His Arg Ser Leu Val Lys Phe Phe Leu Met Thr Glu Ser Ile Ser Ala 705 710 715 720

cca acg act gaa get gag aaa ctt cgt tgg agg gtc cta gag gct gag Pro Thr Thr Glu Ala Glu Lys Leu Arg Trp Arg Val Leu Glu Ala Glu 725 730 735

cgc cca lea ale agt caa ttg cag eat aaa lea cta aUg gaa gca aac Arg Pro Ser Ile Ser Gln Leu Gln Asn Lys Ser Leu Met Glu Ala Asn 740 745 750

aaa gag ttt ctt ggt age cac gaa get let ttg gUg cac age gct goa

-278 Lys Glu Phe Leu Gly Arg His Glu Asp Ser Leu Val His Arg Ala Ala 755 760 765

tat gca gaa aLg ctg tat att tta get cca agc aag aaa acc gag gca Tyr Ala Glu Met Leu Tyr Ile Leu Asp Pro Ser Lys Lys Thr Glu Ala 770 775 780

ale aaa ata att gaa gac lea acc eat aaa gta gUg caa ace eat gaa Ile Lys Ile Ile Glu Asp Ser Thr Asn Lys Val Val Gln Thr Asn Glu 785 790 795 800

get cta gga caa gca age gaa tgg aaa cta aaa gac tgt ata get gtt Ala Leu Gly Gln Ala Arg Glu Trp Lys Leu Lys Asp Cys Ile Ala Val 805 810 815

cat acg ctc cta gac ace gtt ctt ctc gac lea caa gct gcc tcc age His Thr Leu Leu Asp Thr Val Leu Leu Asp Ser Gln Ala Ala Ser Arg 820 825 830

tgg aaa lea cgc tgc gcc gag tat tUt ccc tgt lea act cac ttt gaa Trp Lys Ser Arg Cys Ala Glu Tyr Phe Pro Cys Ser Thr His Phe Glu 835 840 845

ggc aag cat tgc tat ttg atg cct get lea gtg tac aac lea tcc cgc Gly Lys His Cys Ser Leu Met Pro Asp Ser Val Tyr Asn Ser Ser Arg 850 855 860 aag agc eat gag aac ggt gac acg cca aac cat cca atg ggt cag act Lys Ser

Asn Glu Asn Gly Asp Thr Pro Asn His Pro Met Gly Gln Thr 865 870 875 880

gaa ttg agc gac gga caa ctc gaa goa ttc aag agc ctc lea gtt gca Glu Leu Ser Asp Gly Gln Leu Glu Ala Phe Lys Ser Leu Ser Val Ala 885 890 895

acc tga Thr

-279 <210> 68

<211> 897

<212> PRT

<213> Arabidopsis thaliana <400> 68

Met Gly Ala Ser Leu Pro Pro Lys Glu Ala Asn Leu Phe Lys Leu Ile 1 5 10 15

Val Lys Ser Tyr Glu Thr Lys Gln Tyr Lys Lys Gly Leu Lys Ala Ala 20 25 30

Asp Ala Ile Leu Lys Lys Phe Pro Asp His Gly Glu Thr Leu Ser Met 35 40 45

Lys Gly Leu Thr Leu Asn Cys Met Asp Arg Lys Thr Glu Ala Tyr Glu 50 55 60

Leu Val Arg Leu Gly Val Lys Asn Asp Ile Lys Ser His Val Cys Trp 65 70 75 80

His Val Leu Gly Leu Leu Tyr Arg Ser Asp Arg Glu Tyr Arg Glu Ala 85 90 95

Ile Lys Cys Tyr Arg Asn Ala Leu Arg Ile Asp Pro Asp Asn Leu Glu 100 105 110

Ile Leu Arg Asp Leu Ser Leu Leu Gln Ala Gln Met Arg Asp Leu Ser 115 120 125

Gly Phe Val Glu Thr Arg Gln Gln Leu Leu Thr Leu Lys Pro Asn His 130 135 140

Arg Met Asn Trp Ile Gly Phe Ala Val Ser Gln His Leu Asn Ala Asn 145 150 155 160

-280 Ala Ser Lys Ala Val Glu Ile Leu Glu Ala Tyr Glu Gly Thr Leu Glu 165 170 175

Asp Asp Tyr Pro Pro Glu Asn Glu Leu Ile Glu His Thr Glu Met Ile 180 185 190

Leu Tyr Lys Val Ser Leu Leu Glu Glu Ser Gly Ser Phe Asp Lys Ala 195 200 205

Leu Glu Glu Leu His Lys Lys Glu Pro Lys Ile Val Asp Lys Leu Ser 210 215 220

Tyr Lys Glu Gln Glu Val Ser Leu Leu Ser Lys Val Gly Arg Leu Glu 225 230 235 240

Glu Ala Asn Lys Leu Tyr Arg Val Leu Leu Ser Met Asn Pro Asp Asn 245 250 255

Tyr Arg Tyr His Glu Gly Leu Gln Lys Cys Leu Gly Leu Tyr Ser Glu 260 265 270

Ser Gly Gln Tyr Ser Ser Asp Gln Ile Glu Lys Leu Asn Ala Leu Tyr 275 280 285

Gln Ser Leu Ser Glu Gln Tyr Thr Arg Ser Ser Ala Val Lys Arg Ile 290 295 300

Pro Leu Asp Phe Leu Gln Asp Glu Asn Phe Lys Glu Ala Val Ala Lys 305 310 315 320

Tyr Ile Lys Pro Leu Leu Thr Lys Gly Val Pro Ser Leu Phe Ser Asp 325 330 335

Leu Ser Ser Leu Tyr Asp His Pro Arg Lys Pro Asp Ile Leu Glu Gln 340 345 350

-281 Leu Val Val Glu Met Lys His Ser Ile Gly Thr Thr Gly Ser Phe Pro 355 360 365

Gly Ser Asp Val Lys Glu Pro Pro Ser Thr Leu Leu Trp Thr Leu Phe 370 375 380

Phe Leu Ala Gln His Tyr Asp Arg Arg Gly Gln Tyr Asp Val Ala Leu 385 390 395 400

Cys Lys Ile Asp Glu Ala Ile Ala His Thr Pro Thr Val Ile Asp Leu 405 410 415

Tyr Ser Val Lys Ser Arg Ile Met Lys His Ala Gly Asp Leu Thr Ala 420 425 430

Ala Ala Ala Leu Ala Asp Glu Ala Arg Gly Met Asp Leu Ala Asp Arg 435 440 445

Tyr Ile Asn Ser Glu Cys Val Lys Arg Met Leu Gln Ala Asp Gln Val 450 455 460

Pro Leu Ala Glu Lys Thr Ala Val Leu Phe Thr Lys Glu Gly Asp Gln 465 470 475 480

Leu Asn Asn Leu His Asp Met Gln Cys Met Trp Tyr Asp Leu Ala Ser 485 490 495

Gly Asp Ser Tyr Phe Arg Gln Gly Asp Leu Gly Arg Ala Leu Lys Lys 500 505 510

Phe Leu Ala Val Glu Lys His Tyr Ala Asp Ile Ser Glu Asp Gln Phe 515 520 525

Asp Phe His Ser Tyr Cys Leu Arg Lys Met Thr Leu Arg Ser Tyr Val 530 535 540

Asp Met Leu Lys Phe Gln Asp Arg Leu His Ser Phe Pro Tyr Phe His 545 550 555 560

-282 Lys Ala Ala Ile Arg Ala Ile Arg Cys Tyr Leu Lys Leu His Asp Ser 565 570 575

Pro Lys Ser Thr Ala Gly Glu Asp Glu Met Ser Lys Leu Ala Pro Ala 580 585 590

Gln Lys Lys Lys Ile Lys Lys Gln Lys Lys Ala Glu Ala Arg Ala Lys 595 600 605

Lys Glu Ala Glu Ser Lys Ser Glu Glu Ser Thr Ala Ser Gly Ala Ser 610 615 620

Lys Ser Gly Lys Arg Asn Val Lys Pro Val Asp Pro Asp Pro His Gly 625 630 635 640

* Gln Lys Leu Ile Gln Val Glu Glu Pro Met Ala Glu Ala Ser Lys Tyr 645 650 655

Leu Arg Leu Leu Gln Lys His Ser Pro Asn Ser Leu Glu Thr His Leu 660 665 670

Leu Ser Phe Glu Val Asn Met Arg Lys Gln Lys Phe Leu Leu Ala Phe 675 680 685

Gln Ala Val Lys Gln Leu Leu Lys Leu Gly Ala Glu Asn Pro Asp Ser 690 695 700

His Arg Ser Leu Val Lys Phe Phe Leu Met Thr Glu Ser Ile Ser Ala 705 710 715 720

Pro Thr Thr Glu Ala Glu Lys Leu Arg Trp Arg Val Leu Glu Ala Glu 725 730 735

Arg Pro Ser Ile Ser Gln Leu Gln Asn Lys Ser Leu Met Glu Ala Asn 740 745 750

-283 Lys Glu Phe Leu Gly Arg His Glu Asp Ser Leu Val His Arg Ala Ala 755 760 765

Tyr Ala Glu Met Leu Tyr Ile Leu Asp Pro Ser Lys Lys Thr Glu Ala 770 775 780

Ile Lys Ile Ile Glu Asp Ser Thr Asn Lys Val Val Gln Thr Asn Glu 785 790 795 800

Ala Leu Gly Gln Ala Arg Glu Trp Lys Leu Lys Asp Cys Ile Ala Val 805 810 815

His Thr Leu Leu Asp Thr Val Leu Leu Asp Ser Gln Ala Ala Ser Arg 820 825 830

Trp Lys Ser Arg Cys Ala Glu Tyr Phe Pro Cys Ser Thr His Phe Glu 835 840 845

Gly Lys His Cys Ser Leu Met Pro Asp Ser Val Tyr Asn Ser Ser Arg 850 855 860

Lys Ser Asn Glu Asn Gly Asp Thr Pro Asn His Pro Met Gly Gln Thr 865 870 875 880

Glu Leu Ser Asp Gly Gln Leu Glu Ala Phe Lys Ser Leu Ser Val Ala 885 890 895

Thr <210> 69

<211> 852

<212> DNA

<213> Arabidopsis thaliana

-284 <220> <221> CDS

<222> (1)..(852)

<223> <400> 69

aLg aeg ggc tgt gtg eat let att let ccg ccg ccg gtg act tta tac Met Thr Gly Cys Val Asn Ser Ile Ser Pro Pro Pro Val Thr Leu Tyr 1 5 10 15

cgg cat cgt gcc let ccg lea cgg leg tcc ttc lea tta tcc ggc get Arg His Arg Ala Ser Pro Ser Arg Ser Ser Phe Ser Leu Ser Gly Asp 20 25 30

gac tta cac tat cUt tac cgg cac cga cgt gta lea age let cag leg Ala Leu His Ser Leu Tyr Arg His Arg Arg Val Ser Arg Ser Pro Ser 35 40 45

att ale get ccc aaa tUt cag att gtg gcg gct gaa aaa leg gag cct Ile Ile Ala Pro Lys Phe Gln Ile Val Ala Ala Glu Lys Ser Glu Pro 50 55 60

ctg aaa att atg ata lea gga get cat gct let ggt aaa ggt ace caa Leu Lys Ile Met Ile Ser Gly Ala Pro Ala Ser Gly Lys Gly Thr Gln 65 70 75 80

tgc gag ctg att act cac aaa tat ggt ttg gtg cat ale tat gct gga Cys Glu Leu Ile Thr His Lys Tyr Gly Leu Val His Ile Ser Ala Gly 85 90 95

get ttg ctg agg gct gaa ale gct let gga agt gaa eat gga age cgt Asp Leu Leu Arg Ala Glu Ile Ala Ser Gly Ser Glu Asn Gly Arg Arg 100 105 110

gct aaa gaa cat atg gag aaa gga caa ttg gtc cct get gaa ata ght Ala Lys Glu His Met Glu Lys Gly Gln Leu Val Pro Asp Glu Ile Val 115 120 125

-285 gta atg atg gta aaa gat cgt tta tca cag aca gat tca gag caa aaa Val Met Met Val Lys Asp Arg Leu Ser Gln Thr Asp Ser Glu Gln Lys 130 135 140

gga tgg ctt ttg gat gga tat cca agg agt goa tca cag goa aca gct Gly Trp Leu Leu Asp Gly Tyr Pro Arg Ser Ala Ser Gln Ala Thr Ala 145 150 155 160

ctc aag gga ttt gga ttc cag cct gat cta ttc att gtc ctc gaa gtt Leu Lys Gly Phe Gly Phe Gln Pro Asp Leu Phe Ile Val Leu Glu Val 165 170 175

cct gaa gaa att cta att gaa aga gtt ght ggg cgt cga ttg gat cct Pro Glu Glu Ile Leu Ile Glu Arg Val Val Gly Arg Arg Leu Asp Pro 180 185 190

gtc aca gga aag atc tac cac ttg aag tat tag cct cca gag aca gaa Val Thr Gly Lys Ile Tyr His Leu Lys Tyr Ser Pro Pro Glu Thr Glu 195 200 205

gag att gct gtt aga ctc acc caa cgt tUt gat gat acc gaa gag aag Glu Ile Ala Val Arg Leu Thr Gln Arg Phe Asp Asp Thr Glu Glu Lys 210 215 220

goa aaa ctg cgg ctg aag act cat aac caa aat gtg agt gat gtg ctt Ala Lys Leu Arg Leu Lys Thr His Asn Gln Asn Val Ser Asp Val Leu 225 230 235 240

tct atg tac gac gat ata aca att aag atc gag gga aac cgc tca aaa Ser Met Tyr Asp Asp Ile Thr Ile Lys Ile Glu Gly Asn Arg Ser Lys 245 250 255

gag gaa gtg ttt gcc cag atc gat tat tat ctg tcc gaa ttg cEt caa Glu Glu Val Phe Ala Gln Ile Asp Ser Ser Leu Ser Glu Leu Leu Gln 260 265 270

gag agg aac act gat cca agt tca ctt tta agt tga Glu Arg Asn Thr Ala Pro Ser Ser Leu Leu Ser 275 280

-286 <210> 70

<211> 283

<212> PRT

<213> Arabidopsis thaliana <400> 70

Met Thr Gly Cys Val Asn Ser Ile Ser Pro Pro Pro Val Thr Leu Tyr 1 5 10 15

Arg His Arg Ala Ser Pro Ser Arg Ser Ser Phe Ser Leu Ser Gly Asp 20 25 30

Ala Leu His Ser Leu Tyr Arg His Arg Arg Val Ser Arg Ser Pro Ser 35 40 45

Ile Ile Ala Pro Lys Phe Gln Ile Val Ala Ala Glu Lys Ser Glu Pro 50 55 60

Leu Lys Ile Met Ile Ser Gly Ala Pro Ala Ser Gly Lys Gly Thr Gln 65 70 75 80

Cys Glu Leu Ile Thr His Lys Tyr Gly Leu Val His Ile Ser Ala Gly 85 90 95

Asp Leu Leu Arg Ala Glu Ile Ala Ser Gly Ser Glu Asn Gly Arg Arg 100 105 110

Ala Lys Glu His Met Glu Lys Gly Gln Leu Val Pro Asp Glu Ile Val 115 120 125

Val Met Met Val Lys Asp Arg Leu Ser Gln Thr Asp Ser Glu Gln Lys 130 135 140

-287 Gly Trp Leu Leu Asp Gly Tyr Pro Arg Ser Ala Ser Gln Ala Thr Ala 145 150 155 160

Leu Lys Gly Phe Gly Phe Gln Pro Asp Leu Phe Ile Val Leu Glu Val 165 170 175

Pro Glu Glu Ile Leu Ile Glu Arg Val Val Gly Arg Arg Leu Asp Pro 180 185 190

Val Thr Gly Lys Ile Tyr His Leu Lys Tyr Ser Pro Pro Glu Thr Glu 195 200 205

Glu Ile Ala Val Arg Leu Thr Gln Arg Phe Asp Asp Thr Glu Glu Lys 210 215 220

Ala Lys Leu Arg Leu Lys Thr His Asn Gln Asn Val Ser Asp Val Leu 225 230 235 240

Ser Met Tyr Asp Asp Ile Thr Ile Lys Ile Glu Gly Asn Arg Ser Lys 245 250 255

Glu Glu Val Phe Ala Gln Ile Asp Ser Ser Leu Ser Glu Leu Leu Gln 260 265 270

Glu Arg Asn Thr Ala Pro Ser Ser Leu Leu Ser 275 280

<210> 71

<211> 3003

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

-288 <222> (1)..(3003)

<223> <400> 71

atg gtt cac aac gct tat get leg ttt cag ctt ctc aaa get tgt ccc Met Val His Asn Ala Tyr Asp Ser Phe Gln Leu Leu Lys Asp Cys Pro 1 5 10 15

get agg ale get gct gtt gaa tcc tac ggc tcc aag ctc ttc gct gga Ala Arg Ile Asp Ala Val Glu Ser Tyr Gly Ser Lys Leu Phe Ala Gly 20 25 30

tgt tat gac ggt let ctc cgc att tac tat cca ccg gaa let tat gac Cys Tyr Asp Gly Ser Leu Arg Ile Tyr Ser Pro Pro Glu Ser Ser Ala 35 40 45

tcc get cag leg gag chg cat caa gag act tac gtg cta gag aag acg Ser Asp Pro Ser Glu Leu His Gln Glu Thr Tyr Val Leu Glu Lys Thr 50 55 60

gta get gga ttc let aag aaa cag att gtg gcg atg gag gtt ttg gct Val Ala Gly Phe Ser Lys Lys Pro Ile Val Ala Met Glu Val Leu Ala 65 70 75 80

tag age gag ttg cUt ttg tat ctc let gag lea att gcg ttt cat gga Ser Arg Glu Leu Leu Leu Ser Leu Ser Glu Ser Ile Ala Phe His Gly 85 90 95

ctt cct eat ttg gag act gtt gct gtg att act aaa get aaa ggt gct Leu Pro Asn Leu Glu Thr Val Ala Val Ile Thr Lys Ala Lys Gly Ala 100 105 110

eat get tat let tgg get get cgg cgt ggg ttc ttg tgt ttc let agg Asn Ala Tyr Ser Trp Asp Asp Arg Arg Gly Phe Leu Cys Phe Ser Arg 115 120 125

caa aag age gEc tgt gtt ttc aag cac get gga gga gga gga tEt gta Gln Lys Arg Val Cys Val Phe Lys His Asp Gly Gly Gly Gly Phe Val

-289 130 135 140

gag gtc aga gac tat gga gtt cct gat act gtc aag tct att tct tgg Glu Val Arg Asp Tyr Gly Val Pro Asp Thr Val Lys Ser Ile Ser Trp 145 150 155 160

tgt gga gaa aac atc tgt tta ggc att aag aaa gag tat gtg ata ctt Cys Gly Glu Asn Ile Cys Leu Gly Ile Lys Lys Glu Tyr Val Ile Leu 165 170 175

aat act gat aat ggg act ctc tct gag gtg ttt cct tct ggt agg gtt Asn Thr Ala Asn Gly Thr Leu Ser Glu Val Phe Pro Ser Gly Arg Val 180 185 190

gat cct cct ctc gtg ata tct cta cat tct ggt gaa ctt att ttg gga Ala Pro Pro Leu Val Ile Ser Leu Pro Ser Gly Glu Leu Ile Leu Gly 195 200 205

aag gag aac att gga gtt tUt gtt gat caa aat ggg aag ctc ctt caa Lys Glu Asn Ile Gly Val Phe Val Asp Gln Asn Gly Lys Leu Leu Gln 210 215 220

aca gag aga atc tgt tgg tca gag gcc cca acg tct att gtc att caa Thr Glu Arg Ile Cys Trp Ser Glu Ala Pro Thr Ser Ile Val Ile Gln 225 230 235 240

aac cct tat gag ata gac ttg tta cat cgt cga gtt gag gtt cgc ttg Asn Pro Tyr Ala Ile Ala Leu Leu Pro Arg Arg Val Glu Val Arg Leu 245 250 255

ctc cga agt cca tat cct tta ata cag aca att gtt ctt caa aac att Leu Arg Ser Pro Tyr Pro Leu Ile Gln Thr Ile Val Leu Gln Asn Ile 260 265 270

cgt cgc chg gEc aag agc aac aat gat gtg att gtt ggt ttg gat aac Arg Arg Leu Val Lys Ser Asn Asn Ala Val Ile Val Gly Leu Asp Asn 275 280 285

tct gtt tat gtt ctc ttc cat gtc tct att ggt gcc cag att gtg caa Ser Val Tyr Val Leu Phe Pro Val Ser Ile Gly Ala Gln Ile Val Gln

-290 290 295 300

tta ace gct leg gga eat ttt gag gaa gcc tta gct cta tgc aaa gta Leu Thr Ala Ser Gly Asn Phe Glu Glu Ala Leu Ala Leu Cys Lys Val 305 310 315 320

ctc ccc cat get gag lea agc cta cga gct gcg aaa gag agt lea att Leu Pro Pro Asp Glu Ser Ser Leu Arg Ala Ala Lys Glu Ser Ser Ile 325 330 335

cac ace age ttt gct cat tat cUt ttt gag aac ggg agc tat gag gaa His Thr Arg Phe Ala His Tyr Leu Phe Glu Asn Gly Ser Tyr Glu Glu 340 345 350

gcc atg gaa cac ttc ctc gca let caa gta get ale acg cat gta ctt Ala Met Glu His Phe Leu Ala Ser Gln Val Asp Ile Thr His Val Leu 355 360 365

tcc atg tat cca tcc ale att ctt cct aaa ace act att att cct caa Ser Met Tyr Pro Ser Ile Ile Leu Pro Lys Thr Thr Ile Ile Pro Gln 370 375 380

cca get aag atg gtg gac att let ggt get gaa gca let ctg lea age Pro Asp Lys Met Val Asp Ile Ser Gly Asp Glu Ala Ser Leu Ser Arg 385 390 395 400

ggt lea tcc ggc att lea get get aLg gag tat lea let cat cga tat Gly Ser Ser Gly Ile Ser Asp Asp Met Glu Ser Ser Ser Pro Arg Tyr 405 410 415

ttt ttg gaa tat gag gac eat goa gac ctt gaa tat aag aaa atg agt Phe Leu Glu Ser Glu Asp Asn Ala Asp Leu Glu Ser Lys Lys Met Ser 420 425 430

cac aac act ttg atg gct ctt ata aag tac ttg ctg aag agg agg cog His Asn Thr Leu Met Ala Leu Ile Lys Tyr Leu Leu Lys Arg Arg Pro 435 440 445

get gtt ale gag aag gac act let gaa gga ace gaa gag gtc att leg Ala Val Ile Glu Lys Ala Thr Ser Glu Gly Thr Glu Glu Val Ile Ser

-291 450 455 460

get gct gtt ggt aaa act tac ggg goa eat get lea let aag let aag Asp Ala Val Gly Lys Thr Tyr Gly Ala Asn Asp Ser Ser Lys Ser Lys 465 470 475 480

aag tcc agc aag gga cgt ggt aUg ale cct ctt eat lea ggt gca age Lys Ser Ser Lys Gly Arg Gly Met Ile Pro Leu Asn Ser Gly Ala Arg 485 490 495

gag atg gca gca ale ctt get ace gct cht ctc caa goa ctt cta cac Glu Met Ala Ala Ile Leu Asp Thr Ala Leu Leu Gln Ala Leu Leu His 500 505 510

act ggc cag let gga get gct ata gag tta tta aag ggt gtc aac tac Thr Gly Gln Ser Gly Ala Ala Ile Glu Leu Leu Lys Gly Val Asn Tyr 515 520 525

agt gac gtt aag att tgt gag gag att ctc atg aaa agt aaa eat tat Ser Asp Val Lys Ile Cys Glu Glu Ile Leu Met Lys Ser Lys Asn Tyr 530 535 540

let goa cta tta gaa ctg ttc aag agc eat leg atg cac cat gaa gcc Ser Ala Leu Leu Glu Leu Phe Lys Ser Asn Ser Met His His Glu Ala 545 550 555 560

ctt aag ctt cUt aac cag ctg gcg get gag tat aaa ace aac cag lea Leu Lys Leu Leu Asn Gln Leu Ala Asp Glu Ser Lys Thr Asn Gln Ser 565 570 575

caa act get gtt ace cag ata ttt agt cat gag ttg ale ale gaa tat Gln Thr Asp Val Thr Gln Ile Phe Ser Pro Glu Leu Ile Ile Glu Tyr 580 585 590

ctc aag cat ctc tgc agg act get cca atg ctt gtc ttg gag tat let Leu Lys Pro Leu Cys Arg Thr Asp Pro Met Leu Val Leu Glu Tyr Ser 595 600 605

atg ctt gtc chg gaa agc tgt cca act caa acc ale gac ttg ttt ttg Met Leu Val Leu Glu Ser Cys Pro Thr Gln Thr Ile Asp Leu Phe Leu

-292 610 615 620

let gga eat ale lea gct gac ctt gtc eat leg tat ctg aag cag cat Ser Gly Asn Ile Ser Ala Asp Leu Val Asn Ser Tyr Leu Lys Gln His 625 630 635 640

get cca eat aUg cag ggt age tat tta gaa ctt aLg atg gca atg eat Ala Pro Asn Met Gln Gly Arg Tyr Leu Glu Leu Met Met Ala Met Asn 645 650 655

gac acc gca gtt tat gga eat ctc caa aac gag atg gta caa ale tat Asp Thr Ala Val Ser Gly Asn Leu Gln Asn Glu Met Val Gln Ile Tyr 660 665 670

cht lea gaa gtg ctt gac ttg tat gct gca aag agt gag cag cag aaa Leu Ser Glu Val Leu Asp Leu Tyr Ala Ala Lys Ser Ala Gln Gln Lys 675 680 685

tgg get gag aag get cat cct cct gaa agg aaa aaa cta ttg let gag Trp Asp Glu Lys Asp His Pro Pro Glu Arg Lys Lys Leu Leu Ser Ala 690 695 700

tta gag agc ale tcc gga tat agt ccg cag cct ttg ttg aag cgt ctt Leu Glu Ser Ile Ser Gly Tyr Ser Pro Gln Pro Leu Leu Lys Arg Leu 705 710 715 720

cca cgt get gct ctc tat gaa gag cgt gca gtt ata ttg ggc aaa atg Pro Arg Asp Ala Leu Tyr Glu Glu Arg Ala Val Ile Leu Gly Lys Met 725 730 735

aac caa cat gag ctt get ttg tcc ale tat gtt cat aag ctt cat gca Asn Gln His Glu Leu Ala Leu Ser Ile Tyr Val His Lys Leu His Ala 740 745 750

cat get ctg gag ctg get tac tgt get cgt ata tat gag let gtt act Pro Asp Leu Ala Leu Ala Tyr Cys Asp Arg Ile Tyr Glu Ser Val Thr 755 760 765

tat cta cca let gga aaa ccg lea agc eat ale tac ctc ace gtg ctg Tyr Leu Pro Ser Gly Lys Pro Ser Ser Asn Ile Tyr Leu Thr Val Leu

-293 770 775 780

caa ata tac ctg aat cct aag aaa agc gca aaa gac ttt gca aaa cga Gln Ile Tyr Leu Asn Pro Lys Lys Ser Ala Lys Asp Phe Ala Lys Arg 785 790 795 800

att gta gct cta gga tca tCc gaa agt tca gac acc aca aaa atg atg Ile Val Ala Leu Gly Ser Phe Glu Ser Ser Asp Thr Thr Lys Met Met 805 810 815

gac tat gtt tta tct tca aaa gat aaa gga ggc cga tcc aag aaa att Asp Ser Val Leu Ser Ser Lys Ala Lys Gly Gly Arg Ser Lys Lys Ile 820 825 830

gtt gca ata gaa ggc gct gag gat aUg cga gtt ggt ctc agt agc agc Val Ala Ile Glu Gly Ala Glu Asp Met Arg Val Gly Leu Ser Ser Ser 835 840 845

act gac agt gga aga agc gat gtt gat act gaa gaa ccc ttg gaa gaa Thr Asp Ser Gly Arg Ser Asp Val Asp Thr Glu Glu Pro Leu Glu Glu 850 855 860

gga gac tcc acc gtt aUg atc tct gaa gtt cUt gat ctg ttg agc caa Gly Asp Ser Thr Val Met Ile Ser Glu Val Leu Asp Leu Leu Ser Gln 865 870 875 880

agg tgg gag agg atc aac ggt goa caa gac ctc aag ctt ttg cat aga Arg Trp Glu Arg Ile Asn Gly Ala Gln Ala Leu Lys Leu Leu Pro Arg 885 890 895

gaa act aaa ctc cat aac ctg cht ccg ttt cht goa ccc ctt cta aga Glu Thr Lys Leu His Asn Leu Leu Pro Phe Leu Ala Pro Leu Leu Arg 900 905 910

aat tca agt gaa gat cac aga aac tht tca gEc atc aag agt ttg agg Asn Ser Ser Glu Ala His Arg Asn Phe Ser Val Ile Lys Ser Leu Arg 915 920 925

cag agt gaa aac tta cag gtg aaa gag gaa cta tac aaa cat agg aaa Gln Ser Glu Asn Leu Gln Val Lys Glu Glu Leu Tyr Lys His Arg Lys

-294 930 935 940

gga gta gcg caa gta ace agc gaa agc atg tgc lea ttg tgc aac aag Gly Val Ala Gln Val Thr Ser Glu Ser Met Cys Ser Leu Cys Asn Lys 945 950 955 960

aag ata ggg ace agc gta ttt gct gtt tat ccc aac ggg aaa acg tta Lys Ile Gly Thr Ser Val Phe Ala Val Tyr Pro Asn Gly Lys Thr Leu 965 970 975

gtt cac ttt gta tgc ttc age get let caa ggc atg aaa gct gtt tat Val His Phe Val Cys Phe Arg Asp Ser Gln Gly Met Lys Ala Val Ser 980 985 990

aag ace ace cat gga age age cga tga Lys Thr Thr His Gly Arg Arg Arg 995 1000

<210> 72

<211> 1000

<212> PRT

<213> Arabidopsis thaliana <400> 72

Met Val His Asn Ala Tyr Asp Ser Phe Gln Leu Leu Lys Asp Cys Pro 1 5 10 15

Ala Arg Ile Asp Ala Val Glu Ser Tyr Gly Ser Lys Leu Phe Ala Gly 20 25 30

Cys Tyr Asp Gly Ser Leu Arg Ile Tyr Ser Pro Pro Glu Ser Ser Ala 35 40 45

Ser Asp Pro Ser Glu Leu His Gln Glu Thr Tyr Val Leu Glu Lys Thr 50 55 60

-295 Val Ala Gly Phe Ser Lys Lys Pro Ile Val Ala Met Glu Val Leu Ala 65 70 75 80

Ser Arg Glu Leu Leu Leu Ser Leu Ser Glu Ser Ile Ala Phe His Gly 85 90 95

Leu Pro Asn Leu Glu Thr Val Ala Val Ile Thr Lys Ala Lys Gly Ala 100 105 110

Asn Ala Tyr Ser Trp Asp Asp Arg Arg Gly Phe Leu Cys Phe Ser Arg 115 120 125

Gln Lys Arg Val Cys Val Phe Lys His Asp Gly Gly Gly Gly Phe Val 130 135 140

Glu Val Arg Asp Tyr Gly Val Pro Asp Thr Val Lys Ser Ile Ser Trp 145 150 155 160

Cys Gly Glu Asn Ile Cys Leu Gly Ile Lys Lys Glu Tyr Val Ile Leu 165 170 175

Asn Thr Ala Asn Gly Thr Leu Ser Glu Val Phe Pro Ser Gly Arg Val 180 185 190

Ala Pro Pro Leu Val Ile Ser Leu Pro Ser Gly Glu Leu Ile Leu Gly 195 200 205

Lys Glu Asn Ile Gly Val Phe Val Asp Gln Asn Gly Lys Leu Leu Gln 210 215 220

Thr Glu Arg Ile Cys Trp Ser Glu Ala Pro Thr Ser Ile Val Ile Gln 225 230 235 240

Asn Pro Tyr Ala Ile Ala Leu Leu Pro Arg Arg Val Glu Val Arg Leu 245 250 255

Leu Arg Ser Pro Tyr Pro Leu Ile Gln Thr Ile Val Leu Gln Asn Ile

-296 260 265 270

Arg Arg Leu Val Lys Ser Asn Asn Ala Val Ile Val Gly Leu Asp Asn 275 280 285

Ser Val Tyr Val Leu Phe Pro Val Ser Ile Gly Ala Gln Ile Val Gln 290 295 300

Leu Thr Ala Ser Gly Asn Phe Glu Glu Ala Leu Ala Leu Cys Lys Val 305 310 315 320

Leu Pro Pro Asp Glu Ser Ser Leu Arg Ala Ala Lys Glu Ser Ser Ile 325 330 335

His Thr Arg Phe Ala His Tyr Leu Phe Glu Asn Gly Ser Tyr Glu Glu 340 345 350

Ala Met Glu His Phe Leu Ala Ser Gln Val Asp Ile Thr His Val Leu 355 360 365

Ser Met Tyr Pro Ser Ile Ile Leu Pro Lys Thr Thr Ile Ile Pro Gln 370 375 380

Pro Asp Lys Met Val Asp Ile Ser Gly Asp Glu Ala Ser Leu Ser Arg 385 390 395 400

Gly Ser Ser Gly Ile Ser Asp Asp Met Glu Ser Ser Ser Pro Arg Tyr 405 410 415

Phe Leu Glu Ser Glu Asp Asn Ala Asp Leu Glu Ser Lys Lys Met Ser 420 425 430

His Asn Thr Leu Met Ala Leu Ile Lys Tyr Leu Leu Lys Arg Arg Pro 435 440 445

Ala Val Ile Glu Lys Ala Thr Ser Glu Gly Thr Glu Glu Val Ile Ser 450 455 460

-297 Asp Ala Val Gly Lys Thr Tyr Gly Ala Asn Asp Ser Ser Lys Ser Lys 465 470 475 480

Lys Ser Ser Lys Gly Arg Gly Met Ile Pro Leu Asn Ser Gly Ala Arg 485 490 495

Glu Met Ala Ala Ile Leu Asp Thr Ala Leu Leu Gln Ala Leu Leu His 500 505 510

Thr Gly Gln Ser Gly Ala Ala Ile Glu Leu Leu Lys Gly Val Asn Tyr 515 520 525

Ser Asp Val Lys Ile Cys Glu Glu Ile Leu Met Lys Ser Lys Asn Tyr 530 535 540

Ser Ala Leu Leu Glu Leu Phe Lys Ser Asn Ser Met His His Glu Ala 545 550 555 560

Leu Lys Leu Leu Asn Gln Leu Ala Asp Glu Ser Lys Thr Asn Gln Ser 565 570 575

Gln Thr Asp Val Thr Gln Ile Phe Ser Pro Glu Leu Ile Ile Glu Tyr 580 585 590

Leu Lys Pro Leu Cys Arg Thr Asp Pro Met Leu Val Leu Glu Tyr Ser 595 600 605

Met Leu Val Leu Glu Ser Cys Pro Thr Gln Thr Ile Asp Leu Phe Leu 610 615 620

Ser Gly Asn Ile Ser Ala Asp Leu Val Asn Ser Tyr Leu Lys Gln His 625 630 635 640

Ala Pro Asn Met Gln Gly Arg Tyr Leu Glu Leu Met Met Ala Met Asn 645 650 655

Asp Thr Ala Val Ser Gly Asn Leu Gln Asn Glu Met Val Gln Ile Tyr

-298 660 665 670

Leu Ser Glu Val Leu Asp Leu Tyr Ala Ala Lys Ser Ala Gln Gln Lys 675 680 685

Trp Asp Glu Lys Asp His Pro Pro Glu Arg Lys Lys Leu Leu Ser Ala Leu Glu Ser Ile Ser Gly Tyr Ser Pro Gln Pro Leu Leu Lys Arg Leu Pro Arg Asp Ala Leu Tyr Glu Glu Arg Ala Val Ile Leu Gly Lys Met Asn Gln His Glu Leu Ala Leu Ser Ile Tyr Val His Lys Leu H Pro Asp Leu Ala Leu Ala Tyr Cys Asp Arg Ile Tyr Glu Ser Val Thr 755 760 765

Tyr Leu Pro Ser Gly Lys Pro Ser Ser Asn Ile Tyr Leu Thr Val Leu Gln Ile Tyr Leu Asn Pro Lys Lys Ser Ala Lys Asp Phe Ala Lys Arg Ile Val Ala Leu Gly Ser Phe Glu Ser Ser Asp Thr Thr Lys Met Met 805 810 815

Asp Ser Val Leu Ser Ser Lys Ala Lys Gly Gly Arg Ser Lys Lys Ile Val Ala Ile Glu Gly Ala Glu Asp Met Arg Val Gly Leu Ser Ser Ser Thr Asp Ser Gly Arg Ser Asp Val Asp Thr Glu Glu Pro Leu Glu Glu

-299 Gly Asp Ser Thr Val Met Ile Ser Glu Val Leu Asp Leu Leu Ser Gln 865 870 875 880

Arg Trp Glu Arg Ile Asn Gly Ala Gln Ala Leu Lys Leu Leu Pro Arg 885 890 895

Glu Thr Lys Leu His Asn Leu Leu Pro Phe Leu Ala Pro Leu Leu Arg 900 905 910

Asn Ser Ser Glu Ala His Arg Asn Phe Ser Val Ile Lys Ser Leu Arg 915 920 925

Gln Ser Glu Asn Leu Gln Val Lys Glu Glu Leu Tyr Lys His Arg Lys 930 935 940

Gly Val Ala Gln Val Thr Ser Glu Ser Met Cys Ser Leu Cys Asn Lys 945 950 955 960

Lys Ile Gly Thr Ser Val Phe Ala Val Tyr Pro Asn Gly Lys Thr Leu 965 970 975

Val His Phe Val Cys Phe Arg Asp Ser Gln Gly Met Lys Ala Val Ser 980 985 990

Lys Thr Thr His Gly Arg Arg Arg 995 1000

c210> 73 <211> 816

<212> DNA

<213> Arabidopsis thaliana <220>

-300 <221> CDS

<222> (1)..(816)

<223> <400> 73

atg eat ggt cac tgt tta ttt gca gca let cct cct cgt ctc ttc cat Met Asn Gly His Cys Leu Phe Ala Ala Ser Pro Pro Arg Leu Phe Pro 1 5 10 15

ctt cgc tat ata lea leg agt gtt let cca tcc ggt agt tac age ale Leu Arg Ser Ile Ser Ser Ser Val Ser Pro Ser Gly Ser Tyr Arg Ile 20 25 30

aaa ttc tcc get eat gtc gcc gtt gag tgt cgg eat ctc tgt ttc tcc Lys Phe Ser Asp Asn Val Ala Val Glu Cys Arg Asn Leu Cys Phe Ser 35 40 45

gtt agt ace age caa ggt ata tat gtt cct att ctc cgt get tgc tcc Val Ser Thr Arg Gln Gly Ile Ser Val Pro Ile Leu Arg Asp Cys Ser 50 55 60

ttt cgg att cct let gga caa ttg tgg atg att ctt ggt cct eat ggc Phe Arg Ile Pro Ser Gly Gln Leu Trp Met Ile Leu Gly Pro Asn Gly 65 70 75 80

tgt ggc aaa tcc acc cht ttg aag att tta gct ggt gta gtg eat cca Cys Gly Lys Ser Thr Leu Leu Lys Ile Leu Ala Gly Val Val Asn Pro 85 90 95

tcc agt ggc act gtc ttt gtg gag aag cag aag eat ttt gta tUt cag Ser Ser Gly Thr Val Phe Val Glu Lys Pro Lys Asn Phe Val Phe Gln 100 105 110

eat cct get cat cag gta gtg aLg cat ace gtg gaa get get gtg gca Asn Pro Asp His Gln Val Val Met Pro Thr Val Glu Ala Asp Val Ala 115 120 125

-301 ttt ggt ctt ggc aag tat cat gac aLg eat cag gaa gaa gtt aag let Phe Gly Leu Gly Lys Tyr His Asp Met Asn Gln Glu Glu Val Lys Ser 130 135 140

agg gtg att aaa get ttg gag gct gtt ggt atg cgt get tat atg cag Arg Val Ile Lys Ala Leu Glu Ala Val Gly Met Arg Asp Tyr Met Gln 145 150 155 160

age cag att caa act ctc agt ggt ggt cag aaa caa age att gcc att Arg Pro Ile Gln Thr Leu Ser Gly Gly Gln Lys Gln Arg Ile Ala Ile 165 170 175

gct ggt gct tta gct gaa gag tgc aaa gtg cta ttg ttg get gag ctc Ala Gly Ala Leu Ala Glu Ala Cys Lys Val Leu Leu Leu Asp Glu Leu 180 185 190

ace act tUc cta get gag tat gac cag atg ggt gtg ale aaa gct gta Thr Thr Phe Leu Asp Glu Ser Asp Gln Met Gly Val Ile Lys Ala Val 195 200 205

aaa get ctg ata eat gca aag aaa gga get gtg acg gca tta tgg gUg Lys Asp Leu Ile Asn Ala Lys Lys Gly Asp Val Thr Ala Leu Trp Val 210 215 220

ace cat agg tta gag gag ctc aag tat gcg get gga get gtg tat atg Thr His Arg Leu Glu Glu Leu Lys Tyr Ala Asp Gly Ala Val Tyr Met 225 230 235 240

gag aac ggt age gtg gtc age cat ggt get gca gac acc ale lea get Glu Asn Gly Arg Val Val Arg His Gly Asp Ala Ala Thr Ile Ser Asp 245 250 255

tEc att aaa gcc aaa caa leg let tac att get caa att ggt let tea Phe Ile Lys Ala Lys Gln Ser Ser Tyr Ile Asp Gln Ile Gly Ser 260 265 270

c210> 74 <211> 271

-302 <212> PRT

<213> Arabidopsis thaliana <400> 74

Met Asn Gly His Cys Leu Phe Ala Ala Ser Pro Pro Arg Leu Phe Pro 1 5 10 15

Leu Arg Ser Ile Ser Ser Ser Val Ser Pro Ser Gly Ser Tyr Arg Ile 20 25 30

Lys Phe Ser Asp Asn Val Ala Val Glu Cys Arg Asn Leu Cys Phe Ser 35 40 45

Val Ser Thr Arg Gln Gly Ile Ser Val Pro Ile Leu Arg Asp Cys Ser Phe Arg Ile Pro Ser Gly Gln Leu Trp Met Ile Leu Gly Pro Asn Gly 65 70 75 80

Cys Gly Lys Ser Thr Leu Leu Lys Ile Leu Ala Gly Val Val Asn Pro 85 90 95

Ser Ser Gly Thr Val Phe Val Glu Lys Pro Lys Asn Phe Val Phe Gln 100 105 110

Asn Pro Asp His Gln Val Val Met Pro Thr Val Glu Ala Asp Val Ala 115 120 125

Phe Gly Leu Gly Lys Tyr His Asp Met Asn Gln Glu Glu Val Lys Ser 130 135 140

Arg Val Ile Lys Ala Leu Glu Ala Val Gly Met Arg Asp Tyr Met Gln 145 150 155 160

Arg Pro Ile Gln Thr Leu Ser Gly Gly Gln Lys Gln Arg Ile Ala Ile 165 170 175

-303 Ala Gly Ala Leu Ala Glu Ala Cys Lys Val Leu Leu Leu Asp Glu Leu 180 185 190

Thr Thr Phe Leu Asp Glu Ser Asp Gln Met Gly Val Ile Lys Ala Val 195 200 205

Lys Asp Leu Ile Asn Ala Lys Lys Gly Asp Val Thr Ala Leu Trp Val 210 215 220

Thr His Arg Leu Glu Glu Leu Lys Tyr Ala Asp Gly Ala Val Tyr Met 225 230 235 240

Glu Asn Gly Arg Val Val Arg His Gly Asp Ala Ala Thr Ile Ser Asp 245 250 255

Phe Ile Lys Ala Lys Gln Ser Ser Tyr Ile Asp Gln Ile Gly Ser 260 265 270

<210> 75

<211> 1572

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1572)

*<223> <400> 75

atg gag aac cac tht ght ace tag aaa chg ale cgt gtc tat cta cac Met Glu Asn His Phe Val Thr Ser Lys Leu Ile Arg Val Ser Leu His

-304 1 5 10 15

gaa gtt gag aac cag ctc gaa cta tca cta cgt caa gcc ttc gag aat Glu Val Glu Asn Gln Leu Glu Leu Ser Leu Arg Gln Ala Phe Glu Asn 20 25 30

ctc cag ccg aaa cta cga cca ccg ttc tcc tta gaa ctc cca gac cca Leu GlnPro Lys Leu Arg Pro Pro Phe Ser Leu Glu Leu Pro Asp Pro 35 40 45

caa gag tat ctt gag ctc aat aaa gcc atc gtc tat gga gtt tta tgc Gln Glu Tyr Leu Glu Leu Asn Lys Ala Ile Val Tyr Gly Val Leu Cys 50 55 60

gaa cca aat tcc tct aaa acc cac atc aag cac tta cat gat ctc gtc Glu Pro Asn Ser Ser Lys Thr His Ile Lys His Leu Hls Ala Leu Val 65 70 75 80

act gat ggg tac gcg ttt ttc act agt tta ctt att gga atc gtt gtt Thr Asp Gly Tyr Ala Phe Phe Thr Ser Leu Leu Ile Gly Ile Val Val 85 90 95

gaa ttg tat gtt aag ctt gtt gat tcc gat aag att cag cht att tgg Glu Leu Tyr Val Lys Leu Val Asp Ser Ala Lys Ile Gln Leu Ile Trp 100 105 110

gta act aag gag aLg att gat ght tca agt gtg ggg att gag gat ttg Val Thr Lys Glu Met Ile Asp Val Ser Ser Val Gly Ile Glu Asp Leu 115 120 125

gUt gtg tcg ttg ttg cga cga att gga agt ggg gat tat ggt gat cat Val Val Ser Leu Leu Arg Arg Ile Gly Ser Gly Asp Tyr Gly Asp His 130 135 140

aat ght tgg ctt tgt tat gaa tta gtt agt ttg tEt ctt gag aaa tgg Asn Val Trp Leu Cys Ser Glu Leu Val Ser Leu Phe Leu Glu Lys Trp 145 150 155 160

gaa tgc ttg ctt gat gat tct cca ttg gtg ttg act agt gat ctg tat Glu Cys Leu Leu Asp Asp Ser Pro Leu Val Leu Thr Ser Ala Leu Tyr

-305 165 170 175

agt ttt ctt cgg tta tta gcg gat cat tat agg ght tta ggc gtt gtg Ser Phe Leu Arg Leu Leu Ala Asp His Tyr Arg Val Leu Gly Val Val 180 185 190

aaa ctg gag aat gtg aag aga ttg gag atc aaa ttc tgt gtt aaa atg Lys Leu Glu Asn Val Lys Arg Leu Glu Ile Lys Phe Cys Val Lys Met 195 200 205

ttt aga gag cag ctt cat tta agt ttg aag att gga cgg gac ctt atc Phe Arg Glu Gln Leu His Leu Ser Leu Lys Ile Gly Arg Asp Leu Ile 210 215 220

ctg ttg ttg cag gat ctg tct cat gEc tct gag ttc aga gag ata tgg Leu Leu Leu Gln Asp Leu Ser His Val Ser Glu Phe Arg Glu Ile Trp 225 230 235 240

aac gat ttg gUg tcg aac cat tgc tct gag ata tac cag ttg aag act Asn Asp Leu Val Ser Asn His Cys Ser Glu Ile Tyr Gln Leu Lys Thr 245 250 255

tct agt aga tac ttc cht ctt cga atc act cat gag atg gaa aca caa Ser Ser Arg Tyr Phe Leu Leu Arg Ile Thr Pro Glu Met Glu Thr Gln 260 265 270

tta agg ttt ttg cta gga aat gUt aaa ttg gga agt cat aag cgg cat Leu Arg Phe Leu Leu Gly Asn Val Lys Leu Gly Ser His Lys Arg His 275 280 285

cag ata tgg tUc ttg aag aag ttt cht ttg ggt ccg gag aaa gaa aca Gln Ile Trp Phe Leu Lys Lys Phe Leu Leu Gly Pro Glu Lys Glu Thr 290 295 300

ctt ttg ata gat ata gUg aga tUc gUt tgc tgt gtt att cat cca act Leu Leu Ile Asp Ile Val Arg Phe Val Cys Cys Val Ile His Pro Thr 305 310 315 320

aac gaa atc atc aga tca gag atc atg cca aga tgg gat att ata ggt Asn Glu Ile Ile Arg Ser Glu Ile Met Pro Arg Trp Ala Ile Ile Gly

-306 325 330 335

tgg ctt ttg gaa chg tgt agg caa eat cat cac ale gag cga agc gUt Trp Leu Leu Glu Leu Cys Arg Gln Asn His His Ile Glu Arg Ser Val 340 345 350

atg ctg gct ctg ttt tac gac tgg ctc ttc ttt gac gaa age ale get Met Leu Ala Leu Phe Tyr Asp Trp Leu Phe Phe Asp Glu Arg Ile Asp 355 360 365

eat att atg eat gtt gaa cct gct gct ctc ttg atg gta tgg lea ata Asn Ile Met Asn Val Glu Pro Ala Ala Leu Leu Met Val Trp Ser Ile 370 375 380

ccg cag tat cca cac ale act cac tcc tta ctt gaa ttc tta ctt cat Pro Gln Tyr Pro His Ile Thr His Ser Leu Leu Glu Phe Leu Leu His 385 390 395 400

cUt gtc gaa act tat gac ata acc cgt cgc get acg att gta age ggt Leu Val Glu Thr Tyr Asp Ile Thr Arg Arg Asp Thr Ile Val Arg Gly 405 410 415

ttg acg lea goa thc age gaa att gag cga aaa gga gtt att cgg leg Leu Thr Ser Ala Phe Arg Glu Ile Glu Arg Lys Gly Val Ile Arg Ser 420 425 430

ctg get ata ttc cta gca eat cct gca ctt gca cca get ttg aag aag Leu Asp Ile Phe Leu Ala Asn Pro Ala Leu Ala Pro Asp Leu Lys Lys 435 440 445

aag cta gca eat ctg ttg lea tgt cat cag gag aag acg gtt cat gtg Lys Leu Ala Asn Leu Leu Ser Cys His Gln Glu Lys Thr Val His Val 450 455 460

eat ctc eat caa gUt agt gtt ctt let aag caa ace gtt ctt tat leg Asn Leu Asn Gln Val Ser Val Leu Ser Lys Gln Thr Val Leu Ser Ser 465 470 475 480

gaa gct eat tta aaa get tgc agc acc aaa att gtt get act cct gac Glu Ala Asn Leu Lys Asp Cys Ser Thr Lys Ile Val Asp Thr Pro Asp

-307 485 490 495

cag aag ttg gac eat tcc gtt gaa eat cca gca aaa aac cat aag gUt Gln Lys Leu Asp Asn Ser Val Glu Asn Pro Ala Lys Asn His Lys Val 500 505 510

gaa ctg ttc aaa gag ttt ata age ccc lea cgg tga Glu Leu Phe Lys Glu Phe Ile Arg Pro Ser Arg 515 520

<210> 76

<211> 523

<212> PRT

<213> Arabidopsis thaliana <400> 76

Met Glu Asn His Phe Val Thr Ser Lys Leu Ile Arg Val Ser Leu His 1 5 10 15

Glu Val Glu Asn Gln Leu Glu Leu Ser Leu Arg Gln Ala Phe Glu Asn 20 25 30

Leu Gln Pro Lys Leu Arg Pro Pro Phe Ser Leu Glu Leu Pro Asp Pro 35 40 45

Gln Glu Tyr Leu Glu Leu Asn Lys Ala Ile Val Tyr Gly Val Leu Cys 50 55 60

Glu Pro Asn Ser Ser Lys Thr His Ile Lys His Leu His Ala Leu Val 65 70 75 80

Thr Asp Gly Tyr Ala Phe Phe Thr Ser Leu Leu Ile Gly Ile Val Val 85 90 95

Glu Leu Tyr Val Lys Leu Val Asp Ser Ala Lys Ile Gln Leu Ile Trp

- 308 100 105 110

Val Thr Lys Glu Met I le Asp Val Ser Ser Val Gly I le Glu Asp Leu 115 120 125

Val Val Ser Leu Leu Arg Arg Ile Gly Ser Gly Asp Tyr Gly Asp His 130 135 140

Asn Val Trp Leu Cys Ser Glu Leu Val Ser Leu Phe Leu Glu Lys Trp 145 150 155 160

Glu Cys Leu Leu Asp Asp Ser Pro Leu Val Leu Thr Ser Ala Leu Tyr 165 170 175

Ser Phe Leu Arg Leu Leu Ala Asp His Tyr Arg Val Leu Gly Val Val 180 185 190

Lys Leu Glu Asn Val Lys Arg Leu Glu I le Lys Phe Cys Val Lys Met 195 200 205

Phe Arg Glu Gln Leu His Leu Ser Leu Lys Ile Gly Arg Asp Leu Ile 210 215 220

Leu Leu Leu Gln Asp Leu Ser His Val Ser Glu Phe Arg Glu Ile Trp 225 230 235 240

Asn Asp Leu Val Ser Asn His Cys Ser Glu Ile Tyr Gln Leu Lys Thr 245 250 255

Ser Ser Arg Tyr Phe Leu Leu Arg Ile Thr Pro Glu Met Glu Thr Gln 260 265 270

Leu Arg Phe Leu Leu Gly Asn Val Lys Leu Gly Ser His Lys Arg His 275 280 285

Gln I le Trp Phe Leu Lys Lys Phe Leu Leu Gly Pro Glu Lys Glu Thr 290 295 300

-309 Leu Leu Ile Asp Ile Val Arg Phe Val Cys Cys Val Ile His Pro Thr 305 310 315 320

Asn Glu Ile Ile Arg Ser Glu Ile Met Pro Arg Trp Ala Ile Ile Gly 325 330 335

Trp Leu Leu Glu Leu Cys Arg Gln Asn His His Ile Glu Arg Ser Val 340 345 350

Met Leu Ala Leu Phe Tyr Asp Trp Leu Phe Phe Asp Glu Arg Ile Asp 355 360 365

Asn Ile Met Asn Val Glu Pro Ala Ala Leu Leu Met Val Trp Ser Ile 370 375 380

Pro Gln Tyr Pro His Ile Thr His Ser Leu Leu Glu Phe Leu Leu His 385 390 395 400

Leu Val Glu Thr Tyr Asp Ile Thr Arg Arg Asp Thr Ile Val Arg Gly 405 410 415

Leu Thr Ser Ala Phe Arg Glu Ile Glu Arg Lys Gly Val Ile Arg Ser 420 425 430

Leu Asp Ile Phe Leu Ala Asn Pro Ala Leu Ala Pro Asp Leu Lys Lys 435 440 445

Lys Leu Ala Asn Leu Leu Ser Cys His Gln Glu Lys Thr Val His Val 450 455 460

Asn Leu Asn Gln Val Ser Val Leu Ser Lys Gln Thr Val Leu Ser Ser 465 470 475 480

Glu Ala Asn Leu Lys Asp Cys Ser Thr Lys Ile Val Asp Thr Pro Asp 485 490 495

Gln Lys Leu Asp Asn Ser Val Glu Asn Pro Ala Lys Asn His Lys Val

-310 500 505 510

Glu Leu Phe Lys Glu Phe Ile Arg Pro Ser Arg 515 520

<210> 77

<211> 2862

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(2862)

<223> <400> 77

atg gct acg att ace cct let tat att agc eat gac tgg ctc att cct Met Ala Thr Ile Thr Pro Ser Ser Ile Ser Asn Ala Trp Leu Ile Pro 1 5 10 15

gga gct tat ttt act gLa aag aag agt get tgt tcc ale aaa tgt agc Gly Ala Ser Phe Thr Val Lys Lys Ser Asp Cys Ser Ile Lys Cys Ser 20 25 30

ttt tag cgt aaa gct ggg aaa cag att cta lea lea acg cag age ctt Phe Ser Arg Lys Ala Gly Lys Gln Ile Leu Ser Ser Thr Gln Arg Leu 35 40 45

gtg tta cct ttg leg act lea cEt age ttg ttt cct ace cat gga agg Val Leu Pro Leu Ser Thr Ser Leu Arg Leu Phe Pro Thr His Gly Arg 50 55 60

cag ttt gtg ttg cat cct cat cgt age get act ggg act get gtt gtg

-311 Gln Phe Val Leu His Pro His Arg Arg Ala Thr Gly Thr Asp Val Val 65 70 75 80

gag gct gta gag gaa caa get let act cat gtt gtt gag gag get aaa Ala Ala Val Glu Glu Gln Asp Ser Thr Pro Val Val Ala Glu Asp Lys 85 90 95

gaa acc gUg gct agt gag aag lea get gct cct gct cca ace let cag Glu Thr Val Ala Ser Glu Lys Ser Asp Ala Pro Ala Pro Thr Ser Gln 100 105 110

lea agg gga ace goa age cct gga agg aag agt gag atg cct gcg gtt Ser Arg Gly Thr Ala Arg Pro Gly Arg Lys Ser Glu Met Pro Ala Val 115 120 125

aag aac gag gag ctg gtt cct gga gct act ttc act ggg aaa gta cga Lys Asn Glu Glu Leu Val Pro Gly Ala Thr Phe Thr Gly Lys Val Arg 130 135 140

gct att cag cct ttt gga gct ttt gtt get ttt ggt gct tht act get Ala Ile Gln Pro Phe Gly Ala Phe Val Asp Phe Gly Ala Phe Thr Asp 145 150 155 160

gga tta gtc cat gtt let caa ttg agt gac aac ttt gtt aag get ght Gly Leu Val His Val Ser Gln Leu Ser Asp Asn Phe Val Lys Asp Val 165 170 175

leg agt gtt gtc act att gga caa gag gtg aag gta agg cta gtg gaa Ser Ser Val Val Thr Ile Gly Gln Glu Val Lys Val Arg Leu Val Glu 180 185 190

get gac att gag lea aaa cgt att tat tta act aLg cgt gag eat get Ala Asp Ile Glu Ser Lys Arg Ile Ser Leu Thr Met Arg Glu Asn Asp 195 200 205

get cat cct aag cgt cag let ggt ggt agt get aag cag age lea gga Asp Pro Pro Lys Arg Gln Ser Gly Gly Ser Asp Lys Pro Arg Ser Gly 210 215 220

ggg aaa agg get ggt tat aaa gga gga gga cag agg aag gga gaa ggg

-312 Gly Lys Arg Asp Gly Ser Lys Gly Gly Gly Gln Arg Lys Gly Glu Gly 225 230 235 240

tht aac lea aag tUt gcc aaa ggg cag atg ttg get gga gtg gtc aag Phe Asn Ser Lys Phe Ala Lys Gly Gln Met Leu Asp Gly Val Val Lys 245 250 255

eat tta acg agg lea gga gcg ttt ata act ata gga gaa ggc gaa gaa Asn Leu Thr Arg Ser Gly Ala Phe Ile Thr Ile Gly Glu Gly Glu Glu 260 265 270

ggg ttt tta ccg acg gct gag gaa gca get get ggt att gga agc atg Gly Phe Leu Pro Thr Ala Glu Glu Ala Asp Asp Gly Ile Gly Ser Met 275 280 285

atg aUg ggt ggc let leg ttg caa gct gga caa gag gtg aag gtt cgt Met Met Gly Gly Ser Ser Leu Gln Ala Gly Gln Glu Val Lys Val Arg 290 295 300

gtg ttg agg ata goa agg gga cgt gtt act tta ace atg aaa gag gaa Val Leu Arg Ile Ala Arg Gly Arg Val Thr Leu Thr Met Lys Glu Glu 305 310 315 320

get get ggt aag ttt get gaa ace acc act cag gga gtt gtg cat ace Asp Asp Gly Lys Phe Asp Glu Thr Thr Thr Gln Gly Val Val His Thr 325 330 335

gac ace eat cag tUt aUg cUt gct ttc cgt aag aac gaa gag att gct Ala Thr Asn Pro Phe Met Leu Ala Phe Arg Lys Asn Glu Glu Ile Ala 340 345 350

gcg tUt cht gac aag agg gag gaa gag goa gag aag cca cat gEt gag Ala Phe Leu Asp Lys Arg Glu Glu Glu Ala Glu Lys Pro Pro Val Glu 355 360 365

ace cca gLa gag cct gaa get gaa gac let gtc acc lea gct gaa gtc Thr Pro Val Glu Pro Glu Ala Glu Ala Ser Val Thr Ser Ala Glu Val 370 375 380

gag gaa tag gta tgt gtc cca gct gaa gta ace agt gaa gag gtt cac

-313 Glu Glu Ser Val Cys Val Pro Ala Glu Val Thr Ser Glu Glu Val Pro 385 390 395 400

tag lea gaa act ccc aag gta gLa gaa gaa gaa gUg ata gct acc aaa Ser Ser Glu Thr Pro Lys Val Val Glu Glu Glu Val Ile Ala Thr Lys 405 410 415

gct gaa get get leg ccg gaa aaa gaa gag caa acg gaa ace ctt gct Ala Glu Asp Asp Ser Pro Glu Lys Glu Glu Gln Thr Glu Thr Leu Ala 420 425 430

gca gca gct gaa get gaa gag gtg gtt cct cca att cca gaa acc aaa Ala Ala Ala Glu Ala Glu Glu Val Val Pro Pro Ile Pro Glu Thr Lys 435 440 445

agt gaa gag gaa att gtt gag aac let att cct cca aac lea gcc act Ser Glu Glu Glu Ile Val Glu Asn Ser Ile Pro Pro Asn Ser Ala Thr 450 455 460

get gaa gtt lea tat cca gaa gct tta gca agt gaa gag gUt gag aag Asp Glu Val Ser Ser Pro Glu Ala Leu Ala Ser Glu Glu Val Glu Lys 465 470 475 480

gag caa gtg gtt gac gaa ace cct ght get gaa gtc aag act cct gca Glu Gln Val Val Ala Glu Thr Pro Val Asp Glu Val Lys Thr Pro Ala 485 490 495

cct gta gtc ace gaa get tat let gag gaa agt ggc aac acc get act Pro Val Val Thr Glu Ala Ser Ser Glu Glu Ser Gly Asn Thr Ala Thr 500 505 510

get gaa agc ale aaa ggc att lea cca gct cta gtg aag cag ctg age Ala Glu Ser Ile Lys Gly Ile Ser Pro Ala Leu Val Lys Gln Leu Arg 515 520 525

gaa gaa ace ggg goa gga aLg atg gac tgc aag eat gct ctt lea gag Glu Glu Thr Gly Ala Gly Met Met Asp Cys Lys Asn Ala Leu Ser Glu 530 535 540

agt gag ggc get atg gtc aaa gct caa gag tac ctc cgc aag aag gga

-314 Ser Glu Gly Asp Met Val Lys Ala Gln Glu Tyr Leu Arg Lys Lys Gly 545 550 555 560

cta gcg agc gca gat aag aaa gca agc aga gcc aca tcc gag gga aga Leu Ala Ser Ala Asp Lys Lys Ala Ser Arg Ala Thr Ser Glu Gly Arg 565 570 575

att ggt gct tat atc cac gac agc aga atc ggt gtc ctc ttg gag gtt Ile Gly Ala Tyr Ile His Asp Ser Arg Ile Gly Val Leu Leu Glu Val 580 585 590

aat tgt gag act gat ttt gtc tca cgt ggc gac att ttc aag gaa ctt Asn Cys Glu Thr Asp Phe Val Ser Arg Gly Asp Ile Phe Lys Glu Leu 595 600 605

ght gat gat ctg gcg atg cag gtg gct gcg tgt cct caa gta gag tat Val Asp Asp Leu Ala Met Gln Val Ala Ala Cys Pro Gln Val Glu Tyr 610 615 620

cUt gta aca gaa gat gtt tca gaa gaa att gtg aag aaa gaa aaa gag Leu Val Thr Glu Asp Val Ser Glu Glu Ile Val Lys Lys Glu Lys Glu 625 630 635 640

ata gag atg caa aag gaa gat ctt ttg tcg aaa ccg gaa caa ata agg Ile Glu Met Gln Lys Glu Asp Leu Leu Ser Lys Pro Glu Gln Ile Arg 645 650 655

gag aag ata gtg gac ggt cgg ata aag aaa agg cta gat tca cUt gca Glu Lys Ile Val Asp Gly Arg Ile Lys Lys Arg Leu Asp Ser Leu Ala 660 665 670

ttg cUt gag caa cca tac att aaa gac gat aag gtg ata gUt aag gat Leu Leu Glu Gln Pro Tyr Ile Lys Asp Asp Lys Val Ile Val Lys Asp 675 680 685

ctt gLa aag cag agg att gca acc att gga gaa aac atc aaa gtg aag Leu Val Lys Gln Arg Ile Ala Thr Ile Gly Glu Asn Il.e Lys Val Lys 690 695 700

aga tht gtg agg tac act ctc gga gaa ggc ctt gag aag aaa agc cag

-315 Arg Phe Val Arg Tyr Thr Leu Gly Glu Gly Leu Glu Lys Lys Ser Gln 705 710 715 720

gac tht gct gct gag gtt gct gcc caa act gca gct aaa ccg aaa get Asp Phe Ala Ala Glu Val Ala Ala Gln Thr Ala Ala Lys Pro Lys Ala 725 730 735

aaa gaa gag cca aaa gct gaa gag gac aag gaa gct gtt gca agc cca Lys Glu Glu Pro Lys Ala Glu Glu Ala Lys Glu Ala Val Ala Ser Pro 740 745 750

cca act ace gtg ght lea gct get cht gta aag caa ctg cgt gaa gag Pro Thr Thr Val Val Ser Ala Ala Leu Val Lys Gln Leu Arg Glu Glu 755 760 765

ace gga gct gga atg atg get tgc aag aag gca ttg gcg gag ace gga Thr Gly Ala Gly Met Met Asp Cys Lys Lys Ala Leu Ala Ala Thr Gly 770 775 780

gga get ctt gag aaa gca caa gaa tUc ctc age aag aag ggt ctc lea Gly Asp Leu Glu Lys Ala Gln Glu Phe Leu Arg Lys Lys Gly Leu Ser 785 790 795 800

lea get get aaa aaa lea agc cgg ctt gca lea gaa ggg age ale ggt Ser Ala Asp Lys Lys Ser Ser Arg Leu Ala Ser Glu Gly Arg Ile Gly 805 810 815

leg tac ale cac get let cgg att gga gtt ctg ata gaa gtg aac tgt Ser Tyr Ile His Asp Ser Arg Ile Gly Val Leu Ile Glu Val Asn Cys 820 825 830

gag act gac tUt gtc gga age agc gaa aaa ttc aag gaa ttg ght get Glu Thr Asp Phe Val Gly Arg Ser Glu Lys Phe Lys Glu Leu Val Asp 835 840 845

get ctt goa atg caa goa gtg gct eat cca cag gtg caa tat gtt lea Asp Leu Ala Met Gln Ala Val Ala Asn Pro Gln Val Gln Tyr Val Ser 850 855 860

ata gag gac att cca gag gag ata aag cag aaa gaa aaa gag att gag

-316 Ile Glu Asp Ile Pro Glu Glu Ile Lys Gln Lys Glu Lys Glu Ile Glu 865 870 875 880

atg caa age gag get ctt ttg leg aaa cca gag aac ata agg gag aag Met Gln Arg Glu Asp Leu Leu Ser Lys Pro Glu Asn Ile Arg Glu Lys 885 890 895

att gtg gaa gga age ale lea aag agg ctt gga gaa tgg gca ttg ctt Ile Val Glu Gly Arg Ile Ser Lys Arg Leu Gly Glu Trp Ala Leu Leu 900 905 910

gag cag cat tac ale aaa gac gac agt gtt chg gtg aag get ctg gtg Glu Gln Pro Tyr Ile Lys Asp Asp Ser Val Leu Val Lys Asp Leu Val 915 920 925

aag caa ace gUg gct act ctt ggg gaa aac ale aaa gtc age agg ttt Lys Gln Thr Val Ala Thr Leu Gly Glu Asn Ile Lys Val Arg Arg Phe 930 935 940

gtg aag ttt act ctt gga gaa get aac tga Val Lys Phe Thr Leu Gly Glu Asp Asn 945 950

<210> 78

<211> 953

<212> PRT

<213> Arabidopsis thaliana <400> 78

Met Ala Thr Ile Thr Pro Ser Ser Ile Ser Asn Ala Trp Leu Ile Pro 1 5 10 15

Gly Ala Ser Phe Thr Val Lys Lys Ser Asp Cys Ser Ile Lys Cys Ser 20 25 30

Phe Ser Arg Lys Ala Gly Lys Gln Ile Leu Ser Ser Thr Gln Arg Leu

-317 35 40 45

Val Leu Pro Leu Ser Thr Ser Leu Arg Leu Phe Pro Thr His Gly Arg 50 55 60

Gln Phe Val Leu His Pro His Arg Arg Ala Thr Gly Thr Asp Val Val 65 70 75 80

Ala Ala Val Glu Glu Gln Asp Ser Thr Pro Val Val Ala Glu Asp Lys 85 90 95

Glu Thr Val Ala Ser Glu Lys Ser Asp Ala Pro Ala Pro Thr Ser Gln 100 105 110

Ser Arg Gly Thr Ala Arg Pro Gly Arg Lys Ser Glu Met Pro Ala Val 115 120 125

Lys Asn Glu Glu Leu Val Pro Gly Ala Thr Phe Thr Gly Lys Val Arg 130 135 140

Ala Ile Gln Pro Phe Gly Ala Phe Val Asp Phe Gly Ala Phe Thr Asp 145 150 155 160

Gly Leu Val His Val Ser Gln Leu Ser Asp Asn Phe Val Lys Asp Val 165 170 175

Ser Ser Val Val Thr Ile Gly Gln Glu Val Lys Val Arg Leu Val Glu 180 185 190

Ala Asp Ile Glu Ser Lys Arg Ile Ser Leu Thr Met Arg Glu Asn Asp 195 200 205

Asp Pro Pro Lys Arg Gln Ser Gly Gly Ser Asp Lys Pro Arg Ser Gly 210 215 220

Gly Lys Arg Asp Gly Ser Lys Gly Gly Gly Gln Arg Lys Gly Glu Gly 225 230 235 240

-318 Phe Asn Ser Lys Phe Ala Lys Gly Gln Met Leu Asp Gly Val Val Lys 245 250 255

Asn Leu Thr Arg Ser Gly Ala Phe Ile Thr Ile Gly Glu Gly Glu Glu 260 265 270

Gly Phe Leu Pro Thr Ala Glu Glu Ala Asp Asp Gly Ile Gly Ser Met 275 280 285

Met Met Gly Gly Ser Ser Leu Gln Ala Gly Gln Glu Val Lys Val Arg 290 295 300

Val Leu Arg Ile Ala Arg Gly Arg Val Thr Leu Thr Met Lys Glu Glu 305 310 315 320

Asp Asp Gly Lys Phe Asp Glu Thr Thr Thr Gln Gly Val Val His Thr 325 330 335

Ala Thr Asn Pro Phe Met Leu Ala Phe Arg Lys Asn Glu Glu Ile Ala 340 345 350

Ala Phe Leu Asp Lys Arg Glu Glu Glu Ala Glu Lys Pro Pro Val Glu 355 360 365

Thr Pro Val Glu Pro Glu Ala Glu Ala Ser Val Thr Ser Ala Glu Val 370 375 380

Glu Glu Ser Val Cys Val Pro Ala Glu Val Thr Ser Glu Glu Val Pro 385 390 395 400

Ser Ser Glu Thr Pro Lys Val Val Glu Glu Glu Val Ile Ala Thr Lys 405 410 415

Ala Glu Asp Asp Ser Pro Glu Lys Glu Glu Gln Thr Glu Thr Leu Ala 420 425 430

Ala Ala Ala Glu Ala Glu Glu Val Val Pro Pro Ile Pro Glu Thr Lys

-319 435 440 445

Ser Glu Glu Glu Ile Val Glu Asn Ser Ile Pro Pro Asn Ser Ala Thr 450 455 460

Asp Glu Val Ser Ser Pro Glu Ala Leu Ala Ser Glu Glu Val Glu Lys 465 470 475 480

Glu Gln Val Val Ala Glu Thr Pro Val Asp Glu Val Lys Thr Pro Ala 485 490 495

Pro Val Val Thr Glu Ala Ser Ser Glu Glu Ser Gly Asn Thr Ala Thr 500 505 510

Ala Glu Ser Ile Lys Gly Ile Ser Pro Ala Leu Val Lys Gln Leu Arg 515 520 525

Glu Glu Thr Gly Ala Gly Met Met Asp Cys Lys Asn Ala Leu Ser Glu 530 535 540

Ser Glu Gly Asp Met Val Lys Ala Gln Glu Tyr Leu Arg Lys Lys Gly 545 550 555 560

Leu Ala Ser Ala Asp Lys Lys Ala Ser Arg Ala Thr Ser Glu Gly Arg 565 570 575

Ile Gly Ala Tyr Ile Hls Asp Ser Arg Ile Gly Val Leu Leu Glu Val 580 585 590

Asn Cys Glu Thr Asp Phe Val Ser Arg Gly Asp Ile Phe Lys Glu Leu 595 600 605

Val Asp Asp Leu Ala Met Gln Val Ala Ala Cys Pro Gln Val Glu Tyr 610 615 620

Leu Val Thr Glu Asp Val Ser Glu Glu Ile Val Lys Lys Glu Lys Glu 625 630 635 640

-320 Ile Glu Met Gln Lys Glu Asp Leu Leu Ser Lys Pro Glu Gln Ile Arg 645 650 655

Glu Lys Ile Val Asp Gly Arg Ile Lys Lys Arg Leu Asp Ser Leu Ala 660 665 670

Leu Leu Glu Gln Pro Tyr Ile Lys Asp Asp Lys Val Ile Val Lys Asp 675 680 685

Leu Val Lys Gln Arg Ile Ala Thr Ile Gly Glu Asn Ile Lys Val Lys 690 695 700

Arg Phe Val Arg Tyr Thr Leu Gly Glu Gly Leu Glu Lys Lys Ser Gln 705 710 715 720

Asp Phe Ala Ala Glu Val Ala Ala Gln Thr Ala Ala Lys Pro Lys Ala 725 730 735

Lys Glu Glu Pro Lys Ala Glu Glu Ala Lys Glu Ala Val Ala Ser Pro 740 745 750

Pro Thr Thr Val Val Ser Ala Ala Leu Val Lys Gln Leu Arg Glu Glu 755 760 765

Thr Gly Ala Gly Met Met Asp Cys Lys Lys Ala Leu Ala Ala Thr Gly 770 775 780

Gly Asp Leu Glu Lys Ala Gln Glu Phe Leu Arg Lys Lys Gly Leu Ser 785 790 795 800

Ser Ala Asp Lys Lys Ser Ser Arg Leu Ala Ser Glu Gly Arg Ile Gly 805 810 815

Ser Tyr Ile His Asp Ser Arg Ile Gly Val Leu Ile Glu Val Asn Cys 820 825 830

Glu Thr Asp Phe Val Gly Arg Ser Glu Lys Phe Lys Glu Leu Val Asp

-321 835 840 845

Asp Leu Ala Met Gln Ala Val Ala Asn Pro Gln Val Gln Tyr Val Ser 850 855 860

Ile Glu Asp Ile Pro Glu Glu Ile Lys Gln Lys Glu Lys Glu Ile Glu 865 870 875 880

Met Gln Arg Glu Asp Leu Leu Ser Lys Pro Glu Asn Ile Arg Glu Lys 885 890 895

Ile Val Glu Gly Arg Ile Ser Lys Arg Leu Gly Glu Trp Ala Leu Leu 900 905 910

Glu Gln Pro Tyr Ile Lys Asp Asp Ser Val Leu Val Lys Asp Leu Val 915 920 925

Lys Gln Thr Val Ala Thr Leu Gly Glu Asn Ile Lys Val Arg Arg Phe 930 935 940

Val Lys Phe Thr Leu Gly Glu Asp Asn 945 950

<210> 79

<211> 312

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(312)

<223>

-322 <400> 79

atg caa gga gtg tgg agc caa cta tgg agg aaa tat get get tat aag Met Gln Gly Val Trp Ser Gln Leu Trp Arg Lys Tyr Ala Asp Tyr Lys 1 5 10 15

tac eat aag ttc gag age ttt gct gtt tgg gaa atg ale gaa cct tac Tyr Asn Lys Phe Glu Arg Phe Ala Val Trp Glu Met Ile Glu Pro Tyr 20 25 30

cgt cga cca aaa acc ttc ace act ttg att act ale tat gtc gcc gac Arg Arg Pro Lys Thr Phe Thr Thr Leu Ile Thr Ile Tyr Val Ala Ala 35 40 45

ttt tac acc ggc gtc ale ggc gct gca gtt ace gag cag ctc tac aag Phe Tyr Thr Gly Val Ile Gly Ala Ala Val Thr Glu Gln Leu Tyr Lys 50 55 60

gag aag ttt tgg gaa gag cac cca ggg aaa ace gUg cct ctg atg aag Glu Lys Phe Trp Glu Glu His Pro Gly Lys Thr Val Pro Leu Met Lys 65 70 75 80

cca gta ttc tat cga gga cca tgg age gtt tat cgt ggt gag gct att Pro Val Phe Tyr Arg Gly Pro Trp Arg Val Tyr Arg Gly Glu Ala Ile 85 90 95

gct lea get gct agc agc cag tga Ala Ser Asp Ala Ser Ser Gln <210> 80

<211> 103

<212> PRT

<213> Arabidopsis thaliana <400> 80

-323 Met Gln Gly Val Trp Ser Gln Leu Trp Arg Lys Tyr Ala Asp Tyr Lys 1 5 10 15

Tyr Asn Lys Phe Glu Arg Phe Ala Val Trp Glu Met Ile Glu Pro Tyr 20 25 30

Arg Arg Pro Lys Thr Phe Thr Thr Leu Ile Thr Ile Tyr Val Ala Ala 35 40 45

Phe Tyr Thr Gly Val Ile Gly Ala Ala Val Thr Glu Gln Leu Tyr Lys 50 55 60

Glu Lys Phe Trp Glu Glu His Pro Gly Lys Thr Val Pro Leu Met Lys 65 70 75 80

Pro Val Phe Tyr Arg Gly Pro Trp Arg Val Tyr Arg Gly Glu Ala Ile 85 90 95

Ala Ser Asp Ala Ser Ser Gln <210>,31

<211> 1302

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1302)

<223> <400> 81

-324 aLg leg att cat tgt cta acc gaa gag ace gcc aaa act gtt ctt cgc Met Ser Ile Pro Cys Leu Thr Glu Glu Thr Ala Lys Thr Val Leu Arg 1 5 10 15

* cag gtg gag ttc tat ttc agt get agt eat cta ccc att get get ttc Gln Val Glu Phe Tyr Phe Ser Asp Ser Asn Leu Pro Ile Asp Asp Phe 20 25 30

ctc aag aag act gtt ace gag agc gaa get ggc ttg gtg agt ttg gcg Leu Lys Lys Thr Val Thr Glu Ser Glu Asp Gly Leu Val Ser Leu Ala 35 40 45

ttg att tgc tcc tUt agt aag atg age gga tat ttg aag ttg ggt get Leu Ile Cys Ser Phe Ser Lys Met Arg Gly Tyr Leu Lys Leu Gly Asp 50 55 60

tat aaa gga get get att cct gaa get acc ale aaa gct gtt gct get Ser Lys Gly Asp Asp Ile Pro Glu Asp Thr Ile Lys Ala Val Ala Asp 65 70 75 80

act ctt cga acc let let gct ctc aag att let gac get ggg aaa aag Thr Leu Arg Thr Ser Ser Ala Leu Lys Ile Ser Asp Asp Gly Lys Lys 85 90 95

gtt ggt agg agt act gaa ttg ttg aag ctg gaa get ttg att gag caa Val Gly Arg Ser Thr Glu Leu Leu Lys Leu Glu Asp Leu Ile Glu Gln 100 105 110

ctt eat get age ace gta gct gag lea cct ttc tcc tat get gUt aaa Leu Asn Ala Arg Thr Val Ala Ala Ser Pro Phe Ser Tyr Asp Val Lys 115 120 125

agg gaa gac gUg gaa tcc ttt ttc agt cag tat gga aag gtt eat agt Arg Glu Asp Val Glu Ser Phe Phe Ser Gln Tyr Gly Lys Val Asn Ser 130 135 140

gtg agg atg cct cgt cat gUt goa gag tag agg ata ttt let ggt ght Val Arg Met Pro Arg His Val Ala Glu Ser Arg Ile Phe Ser Gly Val 145 150 155 160

-325 gcc ttg gtt gag ttc cct ace gaa gag get gcc cag eat gtt atg aag Ala Leu Val Glu Phe Pro Thr Glu Glu Asp Ala Gln Asn Val Met Lys 165 170 175

cag eat ttg gtc ttt gct ggt cag gag ttg gag ctg aaa cca aag aaa Gln Asn Leu Val Phe Ala Gly Gln Glu Leu Glu Leu Lys Pro Lys Lys 180 185 190

gag ttt get eat gaa agg gag aag get gaa gta aaa ttt get eat tac Glu Phe Asp Asn Glu Arg Glu Lys Asp Glu Val Lys Phe Ala Asn Tyr 195 200 205

caa cct cag aag gga let gca eat cag aag eat ggt let get cac aaa Gln Pro Gln Lys Gly Ser Ala Asn Gln Lys Asn Gly Ser Asp His Lys 210 215 220

aac eat let gct tat gag cca get tat ccc aag ggt ttg ale att lea Asn Asn Ser Ala Tyr Glu Pro Asp Tyr Pro Lys Gly Leu Ile Ile Ser 225 230 235 240

ttc acc ctc aag cgt lea gct gaa gag ggt acc acg gaa caa aaa agt Phe Thr Leu Lys Arg Ser Ala Glu Glu Gly Thr Thr Glu Gln Lys Ser 245 250 255

let gag gag cca act get aag ace atg gaa gaa agt gaa ace aag cca Ser Glu Glu Pro Thr Asp Lys Thr Met Glu Glu Ser Glu Thr Lys Pro 260 265 270

goa get act cat get gct get aaa gaa aac act ggt gag gtt cag gcc Ala Asp Thr Pro Asp Ala Asp Lys Glu Asn Thr Gly Glu Val Gln Ala 275 280 285

gag gga goa gag get gaa get get gag aaa gaa gaa aag ggt get cta Glu Gly Ala Glu Asp Glu Asp Asp Glu Lys Glu Glu Lys Gly Ala Leu 290 295 300

gcc acc cat aaa get eat aag get gtt gtc tta cgt gaa get ctt aug Ala Thr His Lys Asp Asn Lys Asp Val Val Leu Arg Glu Asp Leu Lys 305 310 315 320

-326 gat gtt ttc gga aaa ttt ggt gat gtc aag ttt gUt gat ttc aag atg Ala Val Phe Gly Lys Phe Gly Asp Val Lys Phe Val Asp Phe Lys Met 325 330 335

gga tat gag acg ggt tat cht agg ttt gat gaa cct gaa gca tcc cag Gly Ser Glu Thr Gly Tyr Leu Arg Phe Asp Glu Pro Glu Ala Ser Gln 340 345 350

aaa gcc cgt gca gca gca gta tta gcc aat gaa ggt gga cta gcc gtg Lys Ala Arg Ala Ala Ala Val Leu Ala Asn Glu Gly Gly Leu Ala Val 355 360 365

aag aat tht att gct gtc cta gaa cat gtt att ggc gaa gct gaa aag Lys Asn Phe Ile Ala Val Leu Glu Pro Val Ile Gly Glu Ala Glu Lys 370 375 380

gag tat tgg act ctc cta cga agc aaa gat cgg ttt gac aag ggt ggc Glu Tyr Trp Thr Leu Leu Arg Ser Lys Asp Arg Phe Asp Lys Gly Gly 385 390 395 400

cgt gga gga agg gga gga aga aga gga ggg aga tUc ggg aga aag agg Arg Gly Gly Arg Gly Gly Arg Arg Gly Gly Arg Phe Gly Arg Lys Arg 405 410 415

gga tca gat tca cag ggt ggt cgc tgg aac aaa tct cag aag gtg gaa Gly Ser Asp Ser Pro Gly Gly Arg Trp Asn Lys Ser Gln Lys Val Glu 420 425 430

gca tga Ala <210> 82

<211> 433

<212> PRT

<213> Arabidopsis thaliana

-327 <400> 82

Met Ser Ile Pro Cys Leu Thr Glu Glu Thr Ala Lys Thr Val Leu Arg 1 5 10 15

Gln Val Glu Phe Tyr Phe Ser Asp Ser Asn Leu Pro Ile Asp Asp Phe 20 25 30

Leu Lys Lys Thr Val Thr Glu Ser Glu Asp Gly Leu Val Ser Leu Ala 35 40 45

Leu Ile Cys Ser Phe Ser Lys Met Arg Gly Tyr Leu Lys Leu Gly Asp 50 55 60

Ser Lys Gly Asp Asp Ile Pro Glu Asp Thr Ile Lys Ala Val Ala Asp 65 70 75 80

Thr Leu Arg Thr Ser Ser Ala Leu Lys Ile Ser Asp Asp Gly Lys Lys 85 90 95

Val Gly Arg Ser Thr Glu Leu Leu Lys Leu Glu Asp Leu Ile Glu Gln 100 105 110

Leu Asn Ala Arg Thr Val Ala Ala Ser Pro Phe Ser Tyr Asp Val Lys 115 120 125

Arg Glu Asp Val Glu Ser Phe Phe Ser Gln Tyr Gly Lys Val Asn Ser 130 135 140

Val Arg Met Pro Arg His Val Ala Glu Ser Arg Ile Phe Ser Gly Val 145 150 155 160

Ala Leu Val Glu Phe Pro Thr Glu Glu Asp Ala Gln Asn Val Met Lys 165 170 175

Gln Asn Leu Val Phe Ala Gly Gln Glu Leu Glu Leu Lys Pro Lys Lys 180 185 190

-328 Glu Phe Asp Asn Glu Arg Glu Lys Asp Glu Val Lys Phe Ala Asn Tyr 195 200 205

Gln Pro Gln Lys Gly Ser Ala Asn Gln Lys Asn Gly Ser Asp His Lys 210 215 220

Asn Asn Ser Ala Tyr Glu Pro Asp Tyr Pro Lys Gly Leu Ile Ile Ser 225 230 235 240

Phe Thr Leu Lys Arg Ser Ala Glu Glu Gly Thr Thr Glu Gln Lys Ser 245 250 255 Ser Glu Glu Pro Thr Asp Lys Thr Met Glu Glu Ser Glu Thr Lys Pro 260 265

270

Ala Asp Thr Pro Asp Ala Asp Lys Glu Asn Thr Gly Glu Val Gln Ala 275 280 285

Glu Gly Ala Glu Asp Glu Asp Asp Glu Lys Glu Glu Lys Gly Ala Leu 290 295 300

Ala Thr His Lys Asp Asn Lys Asp Val Val Leu Arg Glu Asp Leu Lys 305 310 315 320

Ala Val Phe Gly Lys Phe Gly Asp Val Lys Phe Val Asp Phe Lys Met 325 330 335

Gly Ser Glu Thr Gly Tyr Leu Arg Phe Asp Glu Pro Glu Ala Ser Gln 340 345 350

Lys Ala Arg Ala Ala Ala Val Leu Ala Asn Glu Gly Gly Leu Ala Val 355 360 365

Lys Asn Phe Ile Ala Val Leu Glu Pro Val Ile Gly Glu Ala Glu Lys 370 375 380

-329 Glu Tyr Trp Thr Leu Leu Arg Ser Lys Asp Arg Phe Asp Lys Gly Gly 385 390 395 400

Arg Gly Gly Arg Gly Gly Arg Arg Gly Gly Arg Phe Gly Arg Lys Arg 405 410 415

Gly Ser Asp Ser Pro Gly Gly Arg Trp Asn Lys Ser Gln Lys Val Glu 420 425 430

Ala <210> 83

<211> 1002

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1002)

<223> <400> 83

atg tac gaa eat eat ctc tta aeg ctc tat lea tgc acc atg eat ctc Met Tyr Glu Asn Asn Leu Leu Thr Leu Ser Ser Cys Thr Met Asn Leu 1 5 10 15

eat ttc gct ttc tcc cca ttc ctt gtc let cag age caa cca ttc let Asn Phe Ala Phe Ser Pro Phe Leu Val Ser Gln Arg Gln Pro Phe Ser 20 25 30

tcc cac aag cgt eat ctt cac act ctc gtt get gtt let get eat tcc Ser His Lys Arg Asn Leu His Thr Leu Val Ala Val Ser Ala Asn Ser

-330 35 40 45

gac aac ctc gcc ggt gaa gat aac ggc gga att tcg gcg gca aat aaa Asp Asn Leu Ala Gly Glu Asp Asn Gly Gly Ile Ser Ala Ala Asn Lys 50 55 60

ggt tct ggg act aca gcg aga gga agg aga tta ctc aag gtt aga gaa Gly Ser Gly Thr Thr Ala Arg Gly Arg Arg Leu Leu Lys Val Arg Glu 65 70 75 80

gag aag cga aaa cgc gac tac gat cgt ctt cac gat tac cca tat tgg Glu Lys Arg Lys Arg Asp Tyr Asp Arg Leu Hls Asp Tyr Pro Ser Trp 85 90 95

gac aag tac ttg ttt ctt tcc ttt tat ttt gca ctc cag gtg ttt gtg Ala Lys Tyr Leu Phe Leu Ser Phe Ser Phe Ala Leu Gln Val Phe Val 100 105 110

ttt ttg cct aag tca cga gaa agt gtg aac ctt ttt ttg gtg aat gat Phe Leu Pro Lys Ser Arg Glu Ser Val Asn Leu Phe Leu Val Asn Asp 115 120 125

aaa tgc agg gta ctg gaa agt gag tgt aaa gat gat gaa gag ctt cga Lys Cys Arg Val Leu Glu Ser Ala Cys Lys Asp Asp Glu Glu Leu Arg 130 135 140

gat gtt ctt ggt gat agc ata gga aat cct gag ctc atg aga aag aag Ala Val Leu Gly Asp Ser Ile Gly Asn Pro Glu Leu Met Arg Lys Lys 145 150 155 160

gtt gaa gaa aga gtt agg aag aag gga aaa gat ttc cag aaa cag aag Val Glu Glu Arg Val Arg Lys Lys Gly Lys Asp Phe Gln Lys Gln Lys 165 170 175

act ggt tct gtg cEt tct thc aaa gEt aac tEc aga gat ttc aat cct Thr Gly Ser Val Leu Ser Phe Lys Val Asn Phe Arg Asp Phe Asn Pro 180 185 190

gta gat tcc ttc ata tgg tUt gag ctc tat gga acg cat tca gat cga Val Asp Ser Phe Ile Trp Phe Glu Leu Tyr Gly Thr Pro Ser Asp Arg

-331 195 200 205

get gtt get ctc att gga agt gtt ata cag gca tgg tat gUt atg ggg Asp Val Asp Leu Ile Gly Ser Val Ile Gln Ala Trp Tyr Val Met Gly 210 215 220

cga ttg ggc gct ttc eat ace tcc aac ttg cag cta gca aac ace tcc Arg Leu Gly Ala Phe Asn Thr Ser Asn Leu Gln Leu Ala Asn Thr Ser 225 230 235 240

cta gaa tat get cct ctc tat gac gca gag aag ggc ttc aaa gtg atg Leu Glu Tyr Asp Pro Leu Tyr Asp Ala Glu Lys Gly Phe Lys Val Met 245 250 255

cat lea leg ttt cat gac att agc get gtc gaa ttt caa gac aac tgg Pro Ser Ser Phe His Asp Ile Ser Asp Val Glu Phe Gln Asp Asn Trp 260 265 270

ggt cgt gtg tgg gtt get ctt ggt act tcc get ale ttc gac ctt get Gly Arg Val Trp Val Asp Leu Gly Thr Ser Asp Ile Phe Ala Leu Asp 275 280 285

gtg ctt ctc aac tgt ttg ace gtt atg agt lea gag tac ttg ggc att Val Leu Leu Asn Cys Leu Thr Val Met Ser Ser Glu Tyr Leu Gly Ile 290 295 300

caa caa gta gLa ttt ggt ggt aaa cga atg gga get tgg gaa gag gga Gln Gln Val Val Phe Gly Gly Lys Arg Met Gly Asp Trp Glu Glu Gly 305 310 315 320

atg ace eat cat get tUt ggg tat aag tac tCc aag ale tga Met Thr Asn Pro Asp Phe Gly Tyr Lys Tyr Phe Lys Ile 325 330

<210> 84

<211> 333

<212> PRT

-332 <213> Arabidopsis thaliana <400> 84

Met Tyr Glu Asn Asn Leu Leu Thr Leu Ser Ser Cys Thr Met Asn Leu 1 5 10 15

Asn Phe Ala Phe Ser Pro Phe Leu Val Ser Gln Arg Gln Pro Phe Ser 20 25 30

Ser His Lys Arg Asn Leu His Thr Leu Val Ala Val Ser Ala Asn Ser 35 40 45

Asp Asn Leu Ala Gly Glu Asp Asn Gly Gly Ile Ser Ala Ala Asn Lys 50 55 60

Gly Ser Gly Thr Thr Ala Arg Gly Arg Arg Leu Leu Lys Val Arg Glu 65 70 75 80

Glu Lys Arg Lys Arg Asp Tyr Asp Arg Leu His Asp Tyr Pro Ser Trp 85 90 95

Ala Lys Tyr Leu Phe Leu Ser Phe Ser Phe Ala Leu Gln Val Phe Val 100 105 110

Phe Leu Pro Lys Ser Arg Glu Ser Val Asn Leu Phe Leu Val Asn Asp 115 120 125

Lys Cys Arg Val Leu Glu Ser Ala Cys Lys Asp Asp Glu Glu Leu Arg 130 135 140

Ala Val Leu Gly Asp Ser Ile Gly Asn Pro Glu Leu Met Arg Lys Lys 145 150 155 160

Val Glu Glu Arg Val Arg Lys Lys Gly Lys Asp Phe Gln Lys Gln Lys 165 170 175

-333 Thr Gly Ser Val Leu Ser Phe Lys Val Asn Phe Arg Asp Phe Asn Pro 180 185 190

Val Asp Ser Phe Ile Trp Phe Glu Leu Tyr Gly Thr Pro Ser Asp Arg 195 200 205

Asp Val Asp Leu Ile Gly Ser Val Ile Gln Ala Trp Tyr Val Met Gly Arg Leu Gly Ala Phe Asn Thr Ser Asn Leu Gln Leu Ala Asn Thr Ser 225 230 235 240

Leu Glu Tyr Asp Pro Leu Tyr Asp Ala Glu Lys Gly Phe Lys Val Met 245 250 255

Pro Ser Ser Phe His Asp Ile Ser Asp Val Glu Phe Gln Asp Asn Trp 260 265 270

Gly Arg Val Trp Val Asp Leu Gly Thr Ser Asp Ile Phe Ala Leu Asp 275 280 285

Val Leu Leu Asn Cys Leu Thr Val Met Ser Ser Glu Tyr Leu Gly Ile Gln Gln Val Val Phe Gly Gly Lys Arg Met Gly Asp Trp Glu Glu Gly Met Thr Asn Pro Asp Phe Gly Tyr Lys Tyr Phe Lys Ile 325 330

<210> 85

<211> 1620

<212> DNA

<213> Arabidopsis thaliana

-334 <220> <221> CDS

<222> (1)..(1620)

<223> <400> 85

aLg atg atg agt agc agc agt agc agt agt eat ggt agt agt agt tat Met Met Met Ser Ser Ser Ser Ser Ser Ser Asn Gly Ser Ser Ser Tyr 1 5 10 15

ace age tgc gtt aaa act cca lea let ace eat act aac att ggg aag Thr Arg Cys Val Lys Thr Pro Ser Ser Thr Asn Thr Asn Ile Gly Lys 20 25 30

aaa ctg aaa ggt tgt gaa eat ggt gtt gLa eat cga aag gcg tta eat Lys Leu Lys Gly Cys Glu Asn Gly Val Val Asn Arg Lys Ala Leu Asn 35 40 45

cga gag aag ata att act ctg caa gaa get gtt gaa aag ttg age aag Arg Glu Lys Ile Ile Thr Leu Gln Glu Asp Val Glu Lys Leu Arg Lys 50 55 60

aag ctg age ctt gaa gaa aac att cac cga goa atg gaa age gca ttt Lys Leu Arg Leu Glu Glu Asn Ile His Arg Ala Met Glu Arg Ala Phe 65 70 75 80

agt agg cat ctt gga gca ctt ccc cgt ctt cct cag ttt cta cct cca Ser Arg Pro Leu Gly Ala Leu Pro Arg Leu Pro Pro Phe Leu Pro Pro 85 90 95

leg gtt ttg gag tta cUt gag gaa gtg get gtt ttg gaa gag gaa ttg Ser Val Leu Glu Leu Leu Ala Glu Val Ala Val Leu Glu Glu Glu Leu 100 105 110

gtt cgg tta gaa gaa cat att gUg cat tgt age caa gaa ttg tat caa Val Arg Leu Glu Glu His Ile Val His Cys Arg Gln Glu Leu Tyr Gln 115 120 125

-335 gaa gca gtt ttt aca tct tca tcg ata gag aat tta aaa tgc tct cct Glu Ala Val Phe Thr Ser Ser Ser Ile Glu Asn Leu Lys Cys Ser Pro 130 135 140

goa ttt cct aag cat tgg cag acc aaa tcc aag tca gct tcc act agt Ala Phe Pro Lys His Trp Gln Thr Lys Ser Lys Ser Ala Ser Thr Ser 145 150 155 160

gct aga gaa tca gaa tca cct cUt tca cgg gca cct tgt tct gtt tca Ala Arg Glu Ser Glu Ser Pro Leu Ser Arg Ala Pro Cys Ser Val Ser 165 170 175

gtg tgt agg aag ggt aaa gaa aac aag ttg agt gct act tct atc aaa Val Cys Arg Lys Gly Lys Glu Asn Lys Leu Ser Ala Thr Ser Ile Lys 180 185 190

aca ccg atg aag aaa acg act att gct cat aca caa ctg aat aag agt Thr Pro Met Lys Lys Thr Thr Ile Ala His Thr Gln Leu Asn Lys Ser 195 200 205

tta gaa gct caa aaa cta aag gat agt cat aga tgt cgc aaa aca aat Leu Glu Ala Gln Lys Leu Lys Asp Ser His Arg Cys Arg Lys Thr Asn 210 215 220

gca gag cgg agc tct cat ggt ggc ggt gat gaa cca aat aaa att tcc Ala Glu Arg Ser Ser His Gly Gly Gly Asp Glu Pro Asn Lys Ile Ser 225 230 235 240

gag gat ttg gtt aaa tgt ctg tat aac att ttc aLg aga atg agc tca Glu Asp Leu Val Lys Cys Leu Ser Asn Ile Phe Met Arg Met Ser Ser 245 250 255

ata aag aga tcc aLg gtt aca aaa tct caa gaa aac gat aaa gat acg Ile Lys Arg Ser Met Val Thr Lys Ser Gln Glu Asn Asp Lys Asp Thr 260 265 270

goa ttc agg gat cat tat gga att tgc tat agt ttt aga aga agg gat Ala Phe Arg Asp Pro Tyr Gly Ile Cys Ser Ser Phe Arg Arg Arg Asp 275 280 285

-336 att ggt cga tat aag aat ttc agt gat gtt gaa gaa gcc tca ctt aac Ile Gly Arg Tyr Lys Asn Phe Ser Asp Val Glu Glu Ala Ser Leu Asn 290 295 300

caa aac aga acg tca agt tcc tct ttg ttt ctc atc cgc caa ctg aaa Gln Asn Arg Thr Ser Ser Ser Ser Leu Phe Leu Ile Arg Gln Leu Lys 305 310 315 320

cga ttg ctt gga aga cUt tat tta gtc aac atg cag aaa ctt aat caa Arg Leu Leu Gly Arg Leu Ser Leu Val Asn Met Gln Lys Leu Asn Gln 325 330 335

caa gag aag tta gat ttc tgg ata aac att tat aac agc tgc atg atg Gln Glu Lys Leu Ala Phe Trp Ile Asn Ile Tyr Asn Ser Cys Met Met 340 345 350

aat ggt ttc ctt gaa cat gga ata ccg gag agc cct gat atg gtg aca Asn Gly Phe Leu Glu His Gly Ile Pro Glu Ser Pro Asp Met Val Thr 355 360 365

tta atg caa aag gcg act ata aat gta gga ggc cac ttt ctc aat gca Leu Met Gln Lys Ala Thr Ile Asn Val Gly Gly His Phe Leu Asn Ala 370 375 380

atc aeg atc gaa cac ttc atc ctc cgc tta ccg cat cac tca aaa tat Ile Thr Ile Glu His Phe Ile Leu Arg Leu Pro His His Ser Lys Tyr 385 390 395 400

att tat cca aag ggt tca aag aaa aat gaa atg goa gtg aga agt aaa Ile Ser Pro Lys Gly Ser Lys Lys Asn Glu Met Ala Val Arg Ser Lys 405 410 415

ttt gga ttg gaa ttg tca gag cca ctt gLa aca ttt gat ctc tca tgt Phe Gly Leu Glu Leu Ser Glu Pro Leu Val Thr Phe Ala Leu Ser Cys 420 425 430

ggt agc tgg tcc tca cac gag gta cgg gtg tac act gag agt aaa gta Gly Ser Trp Ser Ser Pro Ala Val Arg Val Tyr Thr Ala Ser Lys Val 435 440 445

-337 gag gag gag ttg gag gtg gcg aaa age gag tac cta gaa gca leg gtg Glu Glu Glu Leu Glu Val Ala Lys Arg Glu Tyr Leu Glu Ala Ser Val 450 455 460

ggg ata leg gtg gtg aaa ata ggg ata cca aag ctg aLg get tgg tat Gly Ile Ser Val Val Lys Ile Gly Ile Pro Lys Leu Met Asp Trp Tyr 465 470 475 480

agt cat gac ttt gca aag gac att gaa lea ttg ctt get tgg att ttc Ser His Asp Phe Ala Lys Asp Ile Glu Ser Leu Leu Asp Trp Ile Phe 485 490 495

ctt cag ttg cct act gag ttg ggt aaa get gct ctc aac tgt gtt gaa Leu Gln Leu Pro Thr Glu Leu Gly Lys Asp Ala Leu Asn Cys Val Glu 500 505 510

caa ggg aLg let cag tcc cct let let act ctt gtc cat att ale cct Gln Gly Met Ser Gln Ser Pro Ser Ser Thr Leu Val His Ile Ile Pro 515 520 525

tat gac ttc act ttt age tat ctt ttt tcc ale tga Tyr Asp Phe Thr Phe Arg Tyr Leu Phe Ser Ile 530 535

<210> 86

<211> 539

<212> PRT

<213> Arabidopsis thaliana <400> 86

Met Met Met Ser Ser Ser Ser Ser Ser Ser Asn Gly Ser Ser Ser Tyr 1 5 10 15

Thr Arg Cys Val Lys Thr Pro Ser Ser Thr Asn Thr Asn Ile Gly Lys 20 25 30

-338 Lys Leu Lys Gly Cys Glu Asn Gly Val Val Asn Arg Lys Ala Leu Asn 35 40 45

Arg Glu Lys Ile Ile Thr Leu Gln Glu Asp Val Glu Lys Leu Arg Lys Lys Leu Arg Leu Glu Glu Asn Ile His Arg Ala Met Glu Arg Ala Phe 65 70 75 80

Ser Arg Pro Leu Gly Ala Leu Pro Arg Leu Pro Pro Phe Leu Pro Pro 85 90 95

Ser Val Leu Glu Leu Leu Ala Glu Val Ala Val Leu Glu Glu Glu Leu 100 105 110

Val Arg Leu Glu Glu His Ile Val His Cys Arg Gln Glu Leu Tyr Gln 115 120 125

Glu Ala Val Phe Thr Ser Ser Ser Ile Glu Asn Leu Lys Cys Ser Pro 130 135 140

Ala Phe Pro Lys His Trp Gln Thr Lys Ser Lys Ser Ala Ser Thr Ser 145 150 155 160

Ala Arg Glu Ser Glu Ser Pro Leu Ser Arg Ala Pro Cys Ser Val Ser 165 170 175

Val Cys Arg Lys Gly Lys Glu Asn Lys Leu Ser Ala Thr Ser Ile Lys 180 185 190

Thr Pro Met Lys Lys Thr Thr Ile Ala His Thr Gln Leu Asn Lys Ser 195 200 205

Leu Glu Ala Gln Lys Leu Lys Asp Ser His Arg Cys Arg Lys Thr Asn

-339 Ala Glu Arg Ser Ser His Gly Gly Gly Asp Glu Pro Asn Lys Ile Ser 225 230 235 240

Glu Asp Leu Val Lys Cys Leu Ser Asn Ile Phe Met Arg Met Ser Ser 245 250 255

Ile Lys Arg Ser Met Val Thr Lys Ser Gln Glu Asn Asp Lys Asp Thr 260 265 270

Ala Phe Arg Asp Pro Tyr Gly Ile Cys Ser Ser Phe Arg Arg Arg Asp 275 280 285

Ile Gly Arg Tyr Lys Asn Phe Ser Asp Val Glu Glu Ala Ser Leu Asn 290 295 300

Gln Asn Arg Thr Ser Ser Ser Ser Leu Phe Leu Ile Arg Gln Leu Lys 305 310 315 320

Arg Leu Leu Gly Arg Leu Ser Leu Val Asn Met Gln Lys Leu Asn Gln 325 330 335

Gln Glu Lys Leu Ala Phe Trp Ile Asn Ile Tyr Asn Ser Cys Met Met 340 345 350

Asn Gly Phe Leu Glu His Gly Ile Pro Glu Ser Pro Asp Met Val Thr 355 360 365

Leu Met Gln Lys Ala Thr Ile Asn Val Gly Gly His Phe Leu Asn Ala 370 375 380

Ile Thr Ile Glu His Phe Ile Leu Arg Leu Pro His His Ser Lys Tyr 385 390 395 400

Ile Ser Pro Lys Gly Ser Lys Lys Asn Glu Met Ala Val Arg Ser Lys 405 410 415

Phe Gly Leu Glu Leu Ser Glu Pro Leu Val Thr Phe Ala Leu Ser Cys 420 425 430

-340 Gly Ser Trp Ser Ser Pro Ala Val Arg Val Tyr Thr Ala Ser Lys Val 435 440 445

Glu Glu Glu Leu Glu Val Ala Lys Arg Glu Tyr Leu Glu Ala Ser Val 450 455 460

Gly Ile Ser Val Val Lys Ile Gly Ile Pro Lys Leu Met Asp Trp Tyr 465 470 475 480

Ser His Asp Phe Ala Lys Asp Ile Glu Ser Leu Leu Asp Trp Ile Phe 485 490 495

Leu Gln Leu Pro Thr Glu Leu Gly Lys Asp Ala Leu Asn Cys Val Glu 500 505 510

Gln Gly Met Ser Gln Ser Pro Ser Ser Thr Leu Val His Ile Ile Pro 515 520 525

Tyr Asp Phe Thr Phe Arg Tyr Leu Phe Ser Ile 530 535

<210> 87

<211> 1458

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1458)

<223>

-341 <400> 87

atg let agt ccg age agt aac aag ccg aag att gtc aac ggt cct ggt Met Ser Ser Pro Arg Ser Asn Lys Pro Lys Ile Val Asn Gly Pro Gly 1 5 10 15

ggt tat att cta caa gac gtt cct cat ctc att get tac ctt cct get Gly Tyr Ile Leu Gln Asp Val Pro His Leu Ile Asp Tyr Leu Pro Asp 20 25 30

ctt cct act tat cca eat cca ttg caa gac eat cca gct tac lea gtg Leu Pro Thr Tyr Pro Asn Pro Leu Gln Asp Asn Pro Ala Tyr Ser Val 35 40 45

gtt aag caa tac ttt gtt cat gct get get agt gtc cct gag aag gtt Val Lys Gln Tyr Phe Val His Ala Asp Asp Ser Val Pro Glu Lys Val 50 55 60

gtt gtt cac aag get ggt cca age gga gtc cat thc agg cgt gct ggt Val Val His Lys Asp Gly Pro Arg Gly Val His Phe Arg Arg Ala Gly 65 70 75 80

cca cgt caa aag gtt tac ttt gag let gac gaa gtg cat gct tgt ata Pro Arg Gln Lys Val Tyr Phe Glu Ser Asp Glu Val His Ala Cys Ile 85 90 95

gtt ace tgt gga ggt ctc tgt cac ggt ctc eat acc gtg att age gaa Val Thr Cys Gly Gly Leu Cys Pro Gly Leu Asn Thr Val Ile Arg Glu 100 105 110

gtt gtg agc agc tta lea tac atg tat gga gta aag age att ctt gga Val Val Ser Ser Leu Ser Tyr Met Tyr Gly Val Lys Arg Ile Leu Gly 115 120 125

ale get ggt gga tac age gga ttt tac gac aag eat act ale cac tta Ile Asp Gly Gly Tyr Arg Gly Phe Tyr Ala Lys Asn Thr Ile Pro Leu 130 135 140

aac tat aaa gtc gtg eat get ale cat aaa cgc gga gga ace ale att Asn Ser Lys Val Val Asn Asp Ile His Lys Arg Gly Gly Thr Ile Ile 145 150 155 160

-342 ggg acc lea age ggt gga cat get acc aac aag ata gtt get agc att Gly Thr Ser Arg Gly Gly His Asp Thr Asn Lys Ile Val Asp Ser Ile 165 170 175

caa get cga gga ale eat cag gUt tac att att gga gga get gga acc Gln Asp Arg Gly Ile Asn Gln Val Tyr Ile Ile Gly Gly Asp Gly Thr 180 185 190

cag cga ggt get lea gta ata ttt gag gaa att age age cgt cga cta Gln Arg Gly Ala Ser Val Ile Phe Glu Glu Ile Arg Arg Arg Arg Leu 195 200 205

aaa gtt gct gtg gtt gga att cca aaa act att get eat get att ccg Lys Val Ala Val Val Gly Ile Pro Lys Thr Ile Asp Asn Asp Ile Pro 210 215 220

gtg ata get aaa let ttt ggg ttt gac act gct gtg gag gaa gct caa Val Ile Asp Lys Ser Phe Gly Phe Asp Thr Ala Val Glu Glu Ala Gln 225 230 235 240

cga gcg att aac gca gca cat ght gaa gcc gag agt eat gag eat ggt Arg Ala Ile Asn Ala Ala His Val Glu Ala Glu Ser Asn Glu Asn Gly 245 250 255

ale ggt tEt gtc aag ctt atg ggt cgt tac agc ggg tac ata gag atg Ile Gly Phe Val Lys Leu Met Gly Arg Tyr Ser Gly Tyr Ile Ala Met 260 265 270

tat get ace tta gcc agc age get gtt gac tgt tgc ttg att cac gag Tyr Ala Thr Leu Ala Ser Arg Asp Val Asp Cys Cys Leu Ile Pro Glu 275 280 285

lea cca ttt tac ctc gaa gga gaa ggt gga ctc ttt gag ttc ata gag Ser Pro Phe Tyr Leu Glu Gly Glu Gly Gly Leu Phe Glu Phe Ile Glu 290 295 300

age cgg ctg aag get cat ggt cac aLg gtg att ght ctt get gag ggt Arg Arg Leu Lys Asp His Gly His Met Val Ile Val Leu Ala Glu Gly 305 310 315 320

-343 goa gga cag get ttg aLg tgc aaa agc atg gaa let act cct atg get Ala Gly Gln Asp Leu Met Cys Lys Ser Met Glu Ser Thr Pro Met Asp 325 330 335

gct tat ggg aac aaa cUt ctt aaa get gtc ggc ttg tgg cta lea caa Ala Ser Gly Asn Lys Leu Leu Lys Asp Val Gly Leu Trp Leu Ser Gln 340 345 350

agc ale aag get cat ttt aag aag eat aag atg gtg atg eat ctc aaa Ser Ile Lys Asp His Phe Lys Lys Asn Lys Met Val Met Asn Leu Lys 355 360 365

tac att get cct ace tac atg ale cgg gct gtt cca agt eat gca lea Tyr Ile Asp Pro Thr Tyr Met Ile Arg Ala Val Pro Ser Asn Ala Ser 370 375 380

gac eat gtt tac tgt ace ctt ctt gct cag agc gcg gtt cat ggt gca Asp Asn Val Tyr Cys Thr Leu Leu Ala Gln Ser Ala Val His Gly Ala 385 390 395 400

atg gct ggt tac act ggc tac acc agt ggt ctt gtc eat gga age caa Met Ala Gly Tyr Thr Gly Tyr Thr Ser Gly Leu Val Asn Gly Arg Gln 405 410 415

ace tac ale cct thc tac agg ata ace gag acc cag aac eat gta gtg Thr Tyr Ile Pro Phe Tyr Arg Ile Thr Glu Thr Gln Asn Asn Val Val 420 425 430

att acg get age aLg tgg gag agg cta ttg tat tat aeg aac cag cca Ile Thr Asp Arg Met Trp Ala Arg Leu Leu Ser Ser Thr Asn Gln Pro 435 440 445

agt ttc ttg ggg cat aag get ace tat gaa gag aag aaa gag ttg ccg Ser Phe Leu Gly Pro Lys Asp Thr Ser Glu Glu Lys Lys Glu Leu Pro 450 455 460

gaa ace ccg ctt cEt gac gac gga gct gtc get att cct cct gtg act Glu Thr Pro Leu Leu Asp Asp Gly Ala Val Asp Ile Pro Pro Val Thr 465 470 475 480

-344 aaa gag gtc act aag tga Lys Glu Val Thr Lys <210> 88

<211> 485

<212> PRT

<213> Arabidopsis thaliana <400> 88

Met Ser Ser Pro Arg Ser Asn Lys Pro Lys Ile Val Asn Gly Pro Gly 1 5 10 15

Gly Tyr Ile Leu Gln Asp Val Pro His Leu Ile Asp Tyr Leu Pro Asp 20 25 30

Leu Pro Thr Tyr Pro Asn Pro Leu Gln Asp Asn Pro Ala Tyr Ser Val 35 40 45

Val Lys Gln Tyr Phe Val His Ala Asp Asp Ser Val Pro Glu Lys Val 50 55 60

Val Val His Lys Asp Gly Pro Arg Gly Val His Phe Arg Arg Ala Gly 65 70 75 80

Pro Arg Gln Lys Val Tyr Phe Glu Ser Asp Glu Val His Ala Cys Ile 85 90 95

Val Thr Cys Gly Gly Leu Cys Pro Gly Leu Asn Thr Val Ile Arg Glu 100 105 110

Val Val Ser Ser Leu Ser Tyr Met Tyr Gly Val Lys Arg Ile Leu Gly 115 120 125

-345 Ile Asp Gly Gly Tyr Arg Gly Phe Tyr Ala Lys Asn Thr Ile Pro Leu 130 135 140

Asn Ser Lys Val Val Asn Asp Ile His Lys Arg Gly Gly Thr Ile Ile 145 150 155 160

Gly Thr Ser Arg Gly Gly His Asp Thr Asn Lys Ile Val Asp Ser Ile 165 170 175

Gln Asp Arg Gly Ile Asn Gln Val Tyr Ile Ile Gly Gly Asp Gly Thr 180 185 190

Gln Arg Gly Ala Ser Val Ile Phe Glu Glu Ile Arg Arg Arg Arg Leu 195 200 205

Lys Val Ala Val Val Gly Ile Pro Lys Thr Ile Asp Asn Asp Ile Pro 210 215 220

Val Ile Asp Lys Ser Phe Gly Phe Asp Thr Ala Val Glu Glu Ala Gln 225 230 235 240

Arg Ala Ile Asn Ala Ala His Val Glu Ala Glu Ser Asn Glu Asn Gly 245 250 255

Ile Gly Phe Val Lys Leu Met Gly Arg Tyr Ser Gly Tyr Ile Ala Met 260 265 270

Tyr Ala Thr Leu Ala Ser Arg Asp Val Asp Cys Cys Leu Ile Pro Glu 275 280 285

* Ser Pro Phe Tyr Leu Glu Gly Glu Gly Gly Leu Phe Glu Phe Ile Glu 290 295 300

Arg Arg Leu Lys Asp His Gly His Met Val Ile Val Leu Ala Glu Gly 305 310 315 320

Ala Gly Gln Asp Leu Met Cys Lys Ser Met Glu Ser Thr Pro Met Asp

-346 325 330 335

Ala Ser Gly Asn Lys Leu Leu Lys Asp Val Gly Leu Trp Leu Ser Gln 340 345 350

Ser Ile Lys Asp His Phe Lys Lys Asn Lys Met Val Met Asn Leu Lys 355 360 365

Tyr Ile Asp Pro Thr Tyr Met Ile Arg Ala Val Pro Ser Asn Ala Ser 370 375 380

Asp Asn Val Tyr Cys Thr Leu Leu Ala Gln Ser Ala Val His Gly Ala 385 390 395 400

Met Ala Gly Tyr Thr Gly Tyr Thr Ser Gly Leu Val Asn Gly Arg Gln 405 410 415

Thr Tyr Ile Pro Phe Tyr Arg Ile Thr Glu Thr Gln Asn Asn Val Val 420 425 430

Ile Thr Asp Arg Met Trp Ala Arg Leu Leu Ser Ser Thr Asn Gln Pro 435 440 445

Ser Phe Leu Gly Pro Lys Asp Thr Ser Glu Glu Lys Lys Glu Leu Pro 450 455 460

Glu Thr Pro Leu Leu Asp Asp Gly Ala Val Asp Ile Pro Pro Val Thr 465 470 475 480

Lys Glu Val Thr Lys <210> 89

<211> 1719

<212> DNA

-347 <213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(1719)

<223> <400> 89

atg gct get gag att gtg ccg cag gcg act caa tta gcc gac gta tcc Met Ala Asp Glu Ile Val Pro Pro Ala Thr Gln Leu Ala Ala Val Ser 1 5 10 15

tta gaa aac get gga let acg gtg caa age gct caa ttc let aac cgg Leu Glu Asn Asp Gly Ser Thr Val Gln Arg Ala Gln Phe Ser Asn Arg 20 25 30

gtt ttg att cga acg att ttg get cga cct gac ggc gga gct gga ctc Val Leu Ile Arg Thr Ile Leu Asp Arg Pro Asp Gly Gly Ala Gly Leu 35 40 45

gcc ggt caa acg gUt cga ale ggt ggt tgg gta aaa tcc gga age get Ala Gly Gln Thr Val Arg Ile Gly Gly Trp Val Lys Ser Gly Arg Asp 50 55 60

caa ggg aaa age acg ttt let ttc ctt gag gtt aac get gga let tgt Gln Gly Lys Arg Thr Phe Ser Phe Leu Ala Val Asn Asp Gly Ser Cys 65 70 75 80

cca gcg eat cUt cag gUt atg gUg get cag let ctc tat get gtc let Pro Ala Asn Leu Gln Val Met Val Asp Pro Ser Leu Tyr Asp Val Ser 85 90 95

aac ttg gtt get acg gga act tgt gtg act gtt get gga gtt ttg aag Asn Leu Val Ala Thr Gly Thr Cys Val Thr Val Asp Gly Val Leu Lys 100 105 110

-348 gtt cca ccg aaa ggt aaa ggt acg cag cag cag att gag ctt aac gtt Val Pro Pro Lys Gly Lys Gly Thr Gln Gln Gln Ile Glu Leu Asn Val 115 120 125

gtg aag gtg att get gtt gga acg gUg get gcg let aag tat cca cUt Val Lys Val Ile Asp Val Gly Thr Val Asp Ala Ser Lys Tyr Pro Leu 130 135 140

cct aag act aag ttg act ctt gag act ttg age get gtg ctt cat ctt Pro Lys Thr Lys Leu Thr Leu Glu Thr Leu Arg Asp Val Leu His Leu 145 150 155 160

cgt let age act aac leg ale lea gct gtt gca age att cgt eat gct Arg Ser Arg Thr Asn Ser Ile Ser Ala Val Ala Arg Ile Arg Asn Ala 165 170 175

ctt gct ttt gcg act cac agt tCc ttt caa gag cat agt ttc ctt tac Leu Ala Phe Ala Thr His Ser Phe Phe Gln Glu His Ser Phe Leu Tyr 180 185 190

att cac act cct ale ale acg ace agt get tgt gaa ggt gct ggt gaa Ile His Thr Pro Ile Ile Thr Thr Ser Asp Cys Glu Gly Ala Gly Glu 195 200 205

atg ttc caa gca ace act ttg ale eat tac act gag agg ttg gag cag Met Phe Gln Ala Thr Thr Leu Ile Asn Tyr Thr Glu Arg Leu Glu Gln 210 215 220

get ctc att get aac cct cag cat act gag get get gEt gaa gct gcg Asp Leu Ile Asp Asn Pro Pro Pro Thr Glu Ala Asp Val Glu Ala Ala 225 230 235 240

agg ctc att gtc att gag age ggt eat gtt gLa gcg gaa ctg aaa get Arg Leu Ile Val Ile Glu Arg Gly Asn Val Val Ala Glu Leu Lys Ala 245 250 255

gcc aaa goa agc aag gaa gcg ale act get get ght gct gaa ctt aaa Ala Lys Ala Ser Lys Glu Ala Ile Thr Ala Ala Val Ala Glu Leu Lys 260 265 270

-349 ata gca aag gag act ttt gct cat att get gag agg leg agg ctt age Ile Ala Lys Glu Thr Phe Ala His Ile Asp Glu Arg Ser Arg Leu Arg 275 280 285

cat gga cta cat aag aaa get gga aac att get tat tcc aag get ttc Pro Gly Leu Pro Lys Lys Asp Gly Asn Ile Asp Tyr Ser Lys Asp Phe 290 295 300

ttt ggt cgt caa gct thc ttg ace gtt tcc ggt caa tta caa gtg gag Phe Gly Arg Gln Ala Phe Leu Thr Val Ser Gly Gln Leu Gln Val Glu 305 310 315 320

acc tat gct tgt gct ctt agc eat gtg tat ace ttt ggc cag act thc Thr Tyr Ala Cys Ala Leu Ser Asn Val Tyr Thr Phe Gly Pro Thr Phe 325 330 335

cgg goa gag aac let cac act lea agg cat cUt gct gaa ttc tgg atg Arg Ala Glu Asn Ser His Thr Ser Arg His Leu Ala Glu Phe Trp Met 340 345 350

gUt gag cat gag att gct tht goa get cta gag gac gac atg aac tgt Val Glu Pro Glu Ile Ala Phe Ala Asp Leu Glu Asp Asp Met Asn Cys 355 360 365

goa gag gcg tat gtg aaa tac atg tgc aac tgg ttg ctt gag aaa tgt Ala Glu Ala Tyr Val Lys Tyr Met Cys Asn Trp Leu Leu Glu Lys Cys 370 375 380

tac get gac atg gaa ctt atg get aag eat tUc gac lea gga tgc att Tyr Ala Asp Met Glu Leu Met Ala Lys Asn Phe Asp Ser Gly Cys Ile 385 390 395 400

gac agg cta aaa ttg gtt gcc tat act ccg ttt ggg cgt ata ace tac Asp Arg Leu Lys Leu Val Ala Ser Thr Pro Phe Gly Arg Ile Thr Tyr 405 410 415

act aaa gca ata gag cta cht gag gaa get gtg gct aaa gga aag gaa Thr Lys Ala Ile Glu Leu Leu Glu Glu Ala Val Ala Lys Gly Lys Glu 420 425 430

-350 ttt get aac eat gtg gag tgg gga ale gac tta gcc leg gag cat gaa Phe Asp Asn Asn Val Glu Trp Gly Ile Asp Leu Ala Ser Glu His Glu 435 440 445

age tac ttg ace gag gtt ctg ttt caa aag cca ctt att gtc tat aac Arg Tyr Leu Thr Glu Val Leu Phe Gln Lys Pro Leu Ile Val Tyr Asn 450 455 460

tac ccg aaa gga ale aaa gct tUt tac atg age ctt aac get get gag Tyr Pro Lys Gly Ile Lys Ala Phe Tyr Met Arg Leu Asn Asp Asp Glu 465 470 475 480

aag ace gtt get gcc atg get gtc ctc gtt cca aag gtt gga gaa ctc Lys Thr Val Ala Ala Met Asp Val Leu Val Pro Lys Val Gly Glu Leu 485 490 495

att ggt gga agc caa agg gaa gaa cga tat get gtc ale aaa aag agg Ile Gly Gly Ser Gln Arg Glu Glu Arg Tyr Asp Val Ile Lys Lys Arg 500 505 510

att gag gag atg ggt ctt cca ata gag cca tat gag tgg tac cta gac Ile Glu Glu Met Gly Leu Pro Ile Glu Pro Tyr Glu Trp Tyr Leu Asp 515 520 525

ttg cgc cgt tat gga ace gtg aag cat tgt ggg ttt gga ctt ggc ttc Leu Arg Arg Tyr Gly Thr Val Lys His Cys Gly Phe Gly Leu Gly Phe 530 535 540

gaa cgt atg att ctc ttc gct act gga ctt get aac ale age gac gtt Glu Arg Met Ile Leu Phe Ala Thr Gly Leu Asp Asn Ile Arg Asp Val 545 550 555 560

att cct ttc cct cgc tat cct gga aaa get get cht tga Ile Pro Phe Pro Arg Tyr Pro Gly Lys Ala Asp Leu 565 570

<210> 90

<211> 572

-351 <212> PRT

<213> Arabidopsis thaliana <400> 90

Met Ala Asp Glu Ile Val Pro Pro Ala Thr Gln Leu Ala Ala Val Ser 1 5 10 15

Leu Glu Asn Asp Gly Ser Thr Val Gln Arg Ala Gln Phe Ser Asn Arg 20 25 30

Val Leu Ile Arg Thr Ile Leu Asp Arg Pro Asp Gly Gly Ala Gly Leu 35 40 45

Ala Gly Gln Thr Val Arg Ile Gly Gly Trp Val Lys Ser Gly Arg Asp Gln Gly Lys Arg Thr Phe Ser Phe Leu Ala Val Asn Asp Gly Ser Cys 65 70 75 80

Pro Ala Asn Leu Gln Val Met Val Asp Pro Ser Leu Tyr Asp Val Ser 85 90 95

Asn Leu Val Ala Thr Gly Thr Cys Val Thr Val Asp Gly Val Leu Lys Val Pro Pro Lys Gly Lys Gly Thr Gln Gln Gln Ile Glu Leu Asn Val 115 120 125

Val Lys Val Ile Asp Val Gly Thr Val Asp Ala Ser Lys Tyr Pro Leu 130 135 140

Pro Lys Thr Lys Leu Thr Leu Glu Thr Leu Arg Asp Val Leu His Leu 145 150 155 160

Arg Ser Arg Thr Asn Ser Ile Ser Ala Val Ala Arg Ile Arg Asn Ala 165 170 175

-352 Leu Ala Phe Ala Thr His Ser Phe Phe Gln Glu His Ser Phe Leu Tyr 180 185 190

Ile His Thr Pro Ile Ile Thr Thr Ser Asp Cys Glu Gly Ala Gly Glu 195 200 205

Met Phe Gln Ala Thr Thr Leu Ile Asn Tyr Thr Glu Arg Leu Glu Gln 210 215 220

Asp Leu Ile Asp Asn Pro Pro Pro Thr Glu Ala Asp Val Glu Ala Ala 225 230 235 240

Arg Leu Ile Val Ile Glu Arg Gly Asn Val Val Ala Glu Leu Lys Ala 245 250 255

Ala Lys Ala Ser Lys Glu Ala Ile Thr Ala Ala Val Ala Glu Leu Lys 260 265 270

Ile Ala Lys Glu Thr Phe Ala His Ile Asp Glu Arg Ser Arg Leu Arg 275 280 285

Pro Gly Leu Pro Lys Lys Asp Gly Asn Ile Asp Tyr Ser Lys Asp Phe 290 295 300

Phe Gly Arg Gln Ala Phe Leu Thr Val Ser Gly Gln Leu Gln Val Glu 305 310 315 320

Thr Tyr Ala Cys Ala Leu Ser Asn Val Tyr Thr Phe Gly Pro Thr Phe 325 330 335

Arg Ala Glu Asn Ser His Thr Ser Arg His Leu Ala Glu Phe Trp Met 340 345 350

Val Glu Pro Glu Ile Ala Phe Ala Asp Leu Glu Asp Asp Met Asn Cys 355 360 365

-353 Ala Glu Ala Tyr Val Lys Tyr Met Cys Asn Trp Leu Leu Glu Lys Cys 370 375 380 Tyr Ala Asp Met Glu Leu Met Ala Lys Asn Phe Asp Ser Gly Cys Ile 385 390

395 400

Asp Arg Leu Lys Leu Val Ala Ser Thr Pro Phe Gly Arg Ile Thr Tyr 405 410 415

Thr Lys Ala Ile Glu Leu Leu Glu Glu Ala Val Ala Lys Gly Lys Glu 420 425 430

Phe Asp Asn Asn Val Glu Trp Gly Ile Asp Leu Ala Ser Glu His Glu 435 440 445

Arg Tyr Leu Thr Glu Val Leu Phe Gln Lys Pro Leu Ile Val Tyr Asn 450 455 460

Tyr Pro Lys Gly Ile Lys Ala Phe Tyr Met Arg Leu Asn Asp Asp Glu 465 470 475 480

Lys Thr Val Ala Ala Met Asp Val Leu Val Pro Lys Val Gly Glu Leu 485 490 495

Ile Gly Gly Ser Gln Arg Glu Glu Arg Tyr Asp Val Ile Lys Lys Arg 500 505 510

Ile Glu Glu Met Gly Leu Pro Ile Glu Pro Tyr Glu Trp Tyr Leu Asp 515 520 525

Leu Arg Arg Tyr Gly Thr Val Lys His Cys Gly Phe Gly Leu Gly Phe 530 535 540

Glu Arg Met Ile Leu Phe Ala Thr Gly Leu Asp Asn Ile Arg Asp Val 545 550 555 560

Ile Pro Phe Pro Arg Tyr Pro Gly Lys Ala Asp Leu 565 570

-354 <210> 91

<211> 2379

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

<222> (1)..(2379)

<223> <400> 91

atg eat ctt cag ttg act cta ale tcc tta ctc ttc ttc act tcc gcc Met Asn Leu Gln Leu Thr Leu Ile Ser Leu Leu Phe Phe Thr Ser Ala 1 5 10 15

ata get gaa acc tUc aaa aac ctc get let cat cca cag ttc cct tgt Ile Ala Glu Thr Phe Lys Asn Leu Asp Ser His Pro Gln Phe Pro Cys 20 25 30

aaa cct cct cat ttt agc tat tat ccc ttc tgc eat gtc tat tta tcc Lys Pro Pro His Phe Ser Ser Tyr Pro Phe Cys Asn Val Ser Leu Ser 35 40 45

ata aaa caa cga goa att let ctc gtc tcc ctc ctc atg ctc cca gag Ile Lys Gln Arg Ala Ile Ser Leu Val Ser Leu Leu Met Leu Pro Glu 50 55 60

aag ata ggt cag ctc lea aac ace get get lea gta ccc cgt ctc ggt Lys Ile Gly Gln Leu Ser Asn Thr Ala Ala Ser Val Pro Arg Leu Gly 65 70 75 80

att cct cag tac gag tgg tgg tag gag let tta cac gga ctc gac get

-355 Ile Pro Pro Tyr Glu Trp Trp Ser Glu Ser Leu His Gly Leu Ala Asp 85 90 95

aac ggt cac gga gtt tcc ttc aac ggt leg ale tcc gcc gct act agt Asn Gly Pro Gly Val Ser Phe Asn Gly Ser Ile Ser Ala Ala Thr Ser 100 105 110

ttt cct cag gta ale gta let gct gca let ttc eat age acg cta tgg Phe Pro Gln Val Ile Val Ser Ala Ala Ser Phe Asn Arg Thr Leu Trp 115 120 125

tac gag att gga let gct gtt gcg gtg gaa ggt cgg get atg tac aac Tyr Glu Ile Gly Ser Ala Val Ala Val Glu Gly Arg Ala Met Tyr Asn 130 135 140

ggt ggt caa gct ggg ttg acg ttt tgg gct ccg eat ata eat gtg tUt Gly Gly Gln Ala Gly Leu Thr Phe Trp Ala Pro Asn Ile Asn Val Phe 145 150 155 160

agg get ccg age tgg gga age gga cag gag act cct ggt gag get ccg Arg Asp Pro Arg Trp Gly Arg Gly Gln Glu Thr Pro Gly Glu Asp Pro 165 170 175

aag gta gtt tcc gag tat gga gtt gag ttc gtt age ggg ttt caa gag Lys Val Val Ser Glu Tyr Gly Val Glu Phe Val Arg Gly Phe Gln Glu 180 185 190

aag aag aaa agg aag gtt ttg aaa age age ttt agt get get gtt get Lys Lys Lys Arg Lys Val Leu Lys Arg Arg Phe Ser Asp Asp Val Asp 195 200 205

get get cgt cat get get get get get ggg aag ctc atg tta let get Asp Asp Arg His Asp Asp Asp Ala Asp Gly Lys Leu Met Leu Ser Ala 210 215 220

tgt tgt aag cat ttc act gcc tat get ttg gaa aaa tgg ggg eat tUc Cys Cys Lys His Phe Thr Ala Tyr Asp Leu Glu Lys Trp Gly Asn Phe 225 230 235 240

act age tac gac ttc eat gct gtg gtc ace gaa cag gac atg gaa gac

-356 Thr Arg Tyr Asp Phe Asn Ala Val Val Thr Glu Gln Asp Met Glu Asp 245 250 255

ace tat cag ccc cca ttt gag act tgt ata age get ggt aaa get agc Thr Tyr Gln Pro Pro Phe Glu Thr Cys Ile Arg Asp Gly Lys Ala Ser 260 265 270

tgc ttg aUg tgt lea tat eat gca gtt eat ggg gtc cct gct tgt gcg Cys Leu Met Cys Ser Tyr Asn Ala Val Asn Gly Val Pro Ala Cys Ala 275 280 285

caa gga gac tta tta caa aaa gct cga gtt gag tgg gga ttt gaa ggg Gln Gly Asp Leu Leu Gln Lys Ala Arg Val Glu Trp Gly Phe Glu Gly 290 295 300

tac att ace lea gac tgt get gct gtg gca act att ttt gcg tac caa Tyr Ile Thr Ser Asp Cys Asp Ala Val Ala Thr Ile Phe Ala Tyr Gln 305 310 315 320

gga tat acc aag lea cct gag gaa get gtt gct get gcc ata aaa gca Gly Tyr Thr Lys Ser Pro Glu Glu Ala Val Ala Asp Ala Ile Lys Ala 325 330 335

ggg gtg get ata eat tgt gga ace tac atg ctt cgg cac ace caa let Gly Val Asp Ile Asn Cys Gly Thr Tyr Met Leu Arg His Thr Gln Ser 340 345 350

gcg att gag cag ggg aag gtg agc gaa gaa cta gLa gac cga gct ctg Ala Ile Glu Gln Gly Lys Val Ser Glu Glu Leu Val Asp Arg Ala Leu 355 360 365

cta eat ctc ttt gct gtt caa cUt cgt cEt gga cEt ttt get ggt get Leu Asn Leu Phe Ala Val Gln Leu Arg Leu Gly Leu Phe Asp Gly Asp 370 375 380

cca age age gga cag tac gga aag tta gga lea eat gac att tgt agc Pro Arg Arg Gly Gln Tyr Gly Lys Leu Gly Ser Asn Asp Ile Cys Ser 385 390 395 400

lea gac cac age aaa ttg gca chg gaa gca ace age cag ggt ale gtg

-357 Ser Asp His Arg Lys Leu Ala Leu Glu Ala Thr Arg Gln Gly Ile Val 405 410 415

ctc ctg aaa eat get cac aag ttg ttg cct ttg aac aaa aac cat gtt Leu Leu Lys Asn Asp His Lys Leu Leu Pro Leu Asn Lys Asn His Val 420 425 430

tat lea tta goa ale gtt ggt cca atg gcg eat eat ata agc eat atg Ser Ser Leu Ala Ile Val Gly Pro Met Ala Asn Asn Ile Ser Asn Met 435 440 445

ggc ggt act tat ace gga aag ccg tgt caa cga aag act ttg ttc aeg Gly Gly Thr Tyr Thr Gly Lys Pro Cys Gln Arg Lys Thr Leu Phe Thr 450 455 460

gaa ctt ctg gag tat gtg aag aag ace let tat gag let ggt tgc lea Glu Leu Leu Glu Tyr Val Lys Lys Thr Ser Tyr Ala Ser Gly Cys Ser 465 470 475 480

gac gtg let tgt get tat get acc gga tUt gga gaa gct gtg gcc ale Asp Val Ser Cys Asp Ser Asp Thr Gly Phe Gly Glu Ala Val Ala Ile 485 490 495

gac aag gga gcg get ttt gtc ata gta gtt goa gga tta get ctc let Ala Lys Gly Ala Asp Phe Val Ile Val Val Ala Gly Leu Asp Leu Ser 500 505 510

caa gaa acc gag get aag get cga gtt agt cht let ttg cct ggt aaa Gln Glu Thr Glu Asp Lys Asp Arg Val Ser Leu Ser Leu Pro Gly Lys 515 520 525

cag aaa get cht gtg tat cat gtt get get gtg agc aaa aaa ccg gtg Gln Lys Asp Leu Val Ser His Val Ala Ala Val Ser Lys Lys Pro Val 530 535 540

att ctt ght cta acc ggt gga gga cca gtg get gta acg ttt gct aaa Ile Leu Val Leu Thr Gly Gly Gly Pro Val Asp Val Thr Phe Ala Lys 545 550 555 560

eat gac cag age ale gga agc att ale tgg att ggt tat cca ggt gaa

-358 Asn Asp Pro Arg Ile Gly Ser Ile Ile Trp Ile Gly Tyr Pro Gly Glu 565 570 575

act ggt gga caa gca ctc gct gaa atc ata ttt gga gac tUc aat cca Thr Gly Gly Gln Ala Leu Ala Glu Ile Ile Phe Gly Asp Phe Asn Pro 580 585 590

ggt ggt aga tta ccg aca acg tgg tat ccg gag tca ttc acg gat gtg Gly Gly Arg Leu Pro Thr Thr Trp Tyr Pro Glu Ser Phe Thr Asp Val 595 600 605

gca aLg tcg gat atg cac atg aga gcc aat tca tct cgt gga tat cca Ala Met Ser Asp Met His Met Arg Ala Asn Ser Ser Arg Gly Tyr Pro 610 615 620

gga aga acg tac aga tUc tat acc gga cct caa gtt tac agt ttt ggg Gly Arg Thr Tyr Arg Phe Tyr Thr Gly Pro Gln Val Tyr Ser Phe Gly 625 630 635 640

acc ggt tta agc tac acg aaa tUc gag tac aag atc tta tca gca cca Thr Gly Leu Ser Tyr Thr Lys Phe Glu Tyr Lys Ile Leu Ser Ala Pro 645 650 655

atc aga ctt agc tta tcg gaa ctt ctt cca caa cag tct tct cac aag Ile Arg Leu Ser Leu Ser Glu Leu Leu Pro Gln Gln Ser Ser His Lys 660 665 670

aaa caa cta caa cat gga gaa gaa ctt cga tac tta cag ctc gat gat Lys Gln Leu Gln His Gly Glu Glu Leu Arg Tyr Leu Gln Leu Asp Asp 675 680 685

gtg att gUt aac tat tgc gaa tct chg cgg tEt aac ght cgt gtt cat Val Ile Val Asn Ser Cys Glu Ser Leu Arg Phe Asn Val Arg Val His 690 695 700

gtg agc aat acc gga gaa atc gac ggt agt cat ght gtg atg ctg ttt Val Ser Asn Thr Gly Glu Ile Asp Gly Ser His Val Val Met Leu Phe 705 710 715 720

tcg aaa atg cca ccg gtt tta tct ggt gtt cag gag aag cag ctg att

-359 Ser Lys Met Pro Pro Val Leu Ser Gly Val Pro Glu Lys Gln Leu Ile 725 730 735

ggt tat get cgt gUt cat gtt cgt tcc eat gaa atg atg gaa ace gUg Gly Tyr Asp Arg Val His Val Arg Ser Asn Glu Met Met Glu Thr Val 740 745 750

tUc gta ale get cct tgc aag cag cta agc gta gag eat get gtc ggg Phe Val Ile Asp Pro Cys Lys Gln Leu Ser Val Ala Asn Asp Val Gly 755 760 765

aag age gUg att cct ctg ggg agt cat gtc ttg ttc ttg gga get tta Lys Arg Val Ile Pro Leu Gly Ser His Val Leu Phe Leu Gly Asp Leu 770 775 780

caa cat let ctc let gtt gaa ttc tea Gln His Ser Leu Ser Val Glu Phe 785 790

<210> 92

<211> 792

<212> PRT

<213> Arabidopsis thaliana <400> 92

Met Asn Leu Gln Leu Thr Leu Ile Ser Leu Leu Phe Phe Thr Ser Ala 1 5 10 15

Ile Ala Glu Thr Phe Lys Asn Leu Asp Ser His Pro Gln Phe Pro Cys 20 25 30

Lys Pro Pro His Phe Ser Ser Tyr Pro Phe Cys Asn Val Ser Leu Ser 35 40 45

Ile Lys Gln Arg Ala Ile Ser Leu Val Ser Leu Leu Met Leu Pro Glu 50 55 60

-360 Lys Ile Gly Gln Leu Ser Asn Thr Ala Ala Ser Val Pro Arg Leu Gly Ile Pro Pro Tyr Glu Trp Trp Ser Glu Ser Leu His Gly Leu Ala Asp Asn Gly Pro Gly Val Ser Phe Asn Gly Ser Ile Ser Ala Ala Thr Ser 100 105 110

Phe Pro Gln Val Ile Val Ser Ala Ala Ser Phe Asn Arg Thr Leu Trp 115 120 125

Tyr Glu Ile Gly Ser Ala Val Ala Val Glu Gly Arg Ala Met Tyr Asn Gly Gly Gln Ala Gly Leu Thr Phe Trp Ala Pro Asn Ile Asn Val Phe 145 150 155 160

Arg Asp Pro Arg Trp Gly Arg Gly Gln Glu Thr Pro Gly Glu Asp Pro 165 170 175

Lys Val Val Ser Glu Tyr Gly Val Glu Phe Val Arg Gly Phe Gln Glu 180 185 190

Lys Lys Lys Arg Lys Val Leu Lys Arg Arg Phe Ser Asp Asp Val Asp 195 200 205

Asp Asp Arg His Asp Asp Asp Ala Asp Gly Lys Leu Met Leu Ser Ala 210 215 220

Cys Cys Lys His Phe Thr Ala Tyr Asp Leu Glu Lys Trp Gly Asn Phe Thr Arg Tyr Asp Phe Asn Ala Val Val Thr Glu Gln Asp Met Glu Asp 245 250 255

-361 Thr Tyr Gln Pro Pro Phe Glu Thr Cys Ile Arg Asp Gly Lys Ala Ser 260 265 270

Cys Leu Met Cys Ser Tyr Asn Ala Val Asn Gly Val Pro Ala Cys Ala 275 280 285

Gln Gly Asp Leu Leu Gln Lys Ala Arg Val Glu Trp Gly Phe Glu Gly 290 295 300

Tyr Ile Thr Ser Asp Cys Asp Ala Val Ala Thr Ile Phe Ala Tyr Gln 305 310 315 320

Gly Tyr Thr Lys Ser Pro Glu Glu Ala Val Ala Asp Ala Ile Lys Ala 325 330 335

Gly Val Asp Ile Asn Cys Gly Thr Tyr Met Leu Arg His Thr Gln Ser 340 345 350

Ala Ile Glu Gln Gly Lys Val Ser Glu Glu Leu Val Asp Arg Ala Leu 355 360 365

Leu Asn Leu Phe Ala Val Gln Leu Arg Leu Gly Leu Phe Asp Gly Asp 370 375 380

Pro Arg Arg Gly Gln Tyr Gly Lys Leu Gly Ser Asn Asp Ile Cys Ser 385 390 395 400

Ser Asp His Arg Lys Leu Ala Leu Glu Ala Thr Arg Gln Gly Ile Val 405 410 415

Leu Leu Lys Asn Asp His Lys Leu Leu Pro Leu Asn Lys Asn His Val 420 425 430

Ser Ser Leu Ala Ile Val Gly Pro Met Ala Asn Asn Ile Ser Asn Met 435 440 445

Gly Gly Thr Tyr Thr Gly Lys Pro Cys Gln Arg Lys Thr Leu Phe Thr 450 455 460

-362 Glu Leu Leu Glu Tyr Val Lys Lys Thr Ser Tyr Ala Ser Gly Cys Ser 465 470 475 480

Asp Val Ser Cys Asp Ser Asp Thr Gly Phe Gly Glu Ala Val Ala Ile 485 490 495

Ala Lys Gly Ala Asp Phe Val Ile Val Val Ala Gly Leu Asp Leu Ser 500 505 510

Gln Glu Thr Glu Asp Lys Asp Arg Val Ser Leu Ser Leu Pro Gly Lys 515 520 525

Gln Lys Asp Leu Val Ser Hls Val Ala Ala Val Ser Lys Lys Pro Val 530 535 540

Ile Leu Val Leu Thr Gly Gly Gly Pro Val Asp Val Thr Phe Ala Lys 545 550 555 560

Asn Asp Pro Arg Ile Gly Ser Ile Ile Trp Ile Gly Tyr Pro Gly Glu 565 570 575

Thr Gly Gly Gln Ala Leu Ala Glu Ile Ile Phe Gly Asp Phe Asn Pro 580 585 590

Gly Gly Arg Leu Pro Thr Thr Trp Tyr Pro Glu Ser Phe Thr Asp Val 595 600 605

Ala Met Ser Asp Met Hls Met Arg Ala Asn Ser Ser Arg Gly Tyr Pro 610 615 620

Gly Arg Thr Tyr Arg Phe Tyr Thr Gly Pro Gln Val Tyr Ser Phe Gly 625 630 635 640

Thr Gly Leu Ser Tyr Thr Lys Phe Glu Tyr Lys Ile Leu Ser Ala Pro 645 650 655

-363 Ile Arg Leu Ser Leu Ser Glu Leu Leu Pro Gln Gln Ser Ser His Lys 660 665 670

Lys Gln Leu Gln His Gly Glu Glu Leu Arg Tyr Leu Gln Leu Asp Asp 675 680 685

Val Ile Val Asn Ser Cys Glu Ser Leu Arg Phe Asn Val Arg Val His 690 695 700

Val Ser Asn Thr Gly Glu Ile Asp Gly Ser His Val Val Met Leu Phe 705 710 715 720

Ser Lys Met Pro Pro Val Leu Ser Gly Val Pro Glu Lys Gln Leu Ile 725 730 735

Gly Tyr Asp Arg Val His Val Arg Ser Asn Glu Met Met Glu Thr Val 740 745 750

Phe Val Ile Asp Pro Cys Lys Gln Leu Ser Val Ala Asn Asp Val Gly 755 760 765

Lys Arg Val Ile Pro Leu Gly Ser His Val Leu Phe Leu Gly Asp Leu 770 775 780

Gln His Ser Leu Ser Val Glu Phe 785 790

<210> 93

<211> 1275

<212> DNA

<213> Arabidopsis thaliana <220> <221> CDS

-364 <222> (1)..(1275)

<223> <400> 93

atg ggg aaa gac gaa gag gaa atg cga ggt gag ale gag gag cga cta Met Gly Lys Asp Glu Glu Glu Met Arg Gly Glu Ile Glu Glu Arg Leu 1 5 10 15

ale eat gaa gag tac aag ale tgg aag aag aac act cct ttc ctc tac Ile Asn Glu Glu Tyr Lys Ile Trp Lys Lys Asn Thr Pro Phe Leu Tyr 20 25 30

get ctc gtt att act cac gct ctc gag tgg cct lea ctt act gtt gaa Asp Leu Val Ile Thr His Ala Leu Glu Trp Pro Ser Leu Thr Val Glu 35 40 45

tgg ctt cct gac cgt gaa gaa cat tcc ggt aaa gac tac tcc gtt cag Trp Leu Pro Asp Arg Glu Glu Pro Ser Gly Lys Asp Tyr Ser Val Gln 50 55 60

aag atg att ctc ggt acc cat acc tcc gag agc gag cac eat tac ttg Lys Met Ile Leu Gly Thr His Thr Ser Glu Ser Glu Pro Asn Tyr Leu 65 70 75 80

aLg cta gcc caa gtt cag ctt cat ctt gac get acc gag agt gaa gct Met Leu Ala Gln Val Gln Leu Pro Leu Asp Asp Thr Glu Ser Glu Ala 85 90 95

cgt cag tac get get gac cgc tat gaa ttt ggt ggc ttt ggc tgt gca Arg Gln Tyr Asp Asp Asp Arg Ser Glu Phe Gly Gly Phe Gly Cys Ala 100 105 110

act gga aag gta caa att ale cag cag ata eat cat get ggt gag gtt Thr Gly Lys Val Gln Ile Ile Gln Gln Ile Asn His Asp Gly Glu Val 115 120 125

eat cga gct cgc tat atg cat caa aac cat ttc ata att gct acc aag Asn Arg Ala Arg Tyr Met Pro Gln Asn Pro Phe Ile Ile Ala Thr Lys

-365 130 135 140

ace gtt eat gcg gag gtc tat gtt ttc get tac agt aag cat cca let Thr Val Asn Ala Glu Val Tyr Val Phe Asp Tyr Ser Lys His Pro Ser 145 150 155 160

aag cct cct ctt get ggg gct tgt eat cct get tta aag ctt age ggt Lys Pro Pro Leu Asp Gly Ala Cys Asn Pro Asp Leu Lys Leu Arg Gly 165 170 175

cac agc let gag gga tat ggt ctc tat tgg agt aag ttc aag cag ggt His Ser Ser Glu Gly Tyr Gly Leu Ser Trp Ser Lys Phe Lys Gln Gly 180 185 190

cat ttg ctt agt ggc let get get gct cag ale tgc ttg tgg get att His Leu Leu Ser Gly Ser Asp Asp Ala Gln Ile Cys Leu Trp Asp Ile 195 200 205

aac gct act cct aaa aac aaa let ctg gac gct cag cag att ttt aag Asn Ala Thr Pro Lys Asn Lys Ser Leu Asp Ala Gln Gln Ile Phe Lys 210 215 220

get cat gaa ggg gtt gtg gaa get gtt gca tgg cat ctg age cat gag Ala His Glu Gly Val Val Glu Asp Val Ala Trp His Leu Arg His Glu 225 230 235 240

tac chg ttt gga lea gtt gga get gac caa tac ctt ctc ata tgg get Tyr Leu Phe Gly Ser Val Gly Asp Asp Gln Tyr Leu Leu Ile Trp Asp 245 250 255

chg cgt let cca let gac agt aaa cca gta cag tat gtg gtt get cat Leu Arg Ser Pro Ser Ala Ser Lys Pro Val Gln Ser Val Val Ala His 260 265 270

tag aUg gag gtt aac tgc tta gcc ttc eat cca ttt eat gag tgg gtt Ser Met Glu Val Asn Cys Leu Ala Phe Asn Pro Phe Asn Glu Trp Val 275 280 285

gtg goa ace gga lea act gac aag act gtt aaa tta ttc get cta cgg Val Ala Thr Gly Ser Thr Asp Lys Thr Val Lys Leu Phe Asp Leu Arg

-366 290 295 300

aag cta agc acc gct ctt cac ace ttt get agc cac aaa gag gag gUt Lys Leu Ser Thr Ala Leu His Thr Phe Asp Ser His Lys Glu Glu Val 305 310 315 320

ttt caa ght ggt tgg aac cca aag aac gag act att tta gct lea tgt Phe Gln Val Gly Trp Asn Pro Lys Asn Glu Thr Ile Leu Ala Ser Cys 325 330 335

tgc ctt ggt age age ctt atg gtt tgg gac ctt agc agg ale get gag Cys Leu Gly Arg Arg Leu Met Val Trp Asp Leu Ser Arg Ile Asp Glu 340 345 350

gaa cag ace gtg gag gac gca gaa gac ggc cca cct gag ctg ctg tht Glu Gln Thr Val Glu Asp Ala Glu Asp Gly Pro Pro Glu Leu Leu Phe 355 360 365

att cac ggt ggt cac act agc aaa att lea get tUc leg tgg aac cct Ile His Gly Gly His Thr Ser Lys Ile Ser Asp Phe Ser Trp Asn Pro 370 375 380

tgt gaa get tgg gtt att tcc agt gtt get gag gac aac ata ctc caa Cys Glu Asp Trp Val Ile Ser Ser Val Ala Glu Asp Asn Ile Leu Gln 385 390 395 400

ata tgg caa aLg gct gaa aac ale tat cat get gag get gac gct cca Ile Trp Gln Met Ala Glu Asn Ile Tyr His Asp Glu Asp Asp Ala Pro 405 410 415

ggg gee gaa cca lea aaa gct let tag Gly Glu Glu Pro Ser Lys Ala Ser <210> 94

<211> 424

<212> PRT

-367 <213> Arabidopsis thaliana <400> 94

Met Gly Lys Asp Glu Glu Glu Met Arg Gly Glu Ile Glu Glu Arg Leu Ile Asn Glu Glu Tyr Lys Ile Trp Lys Lys Asn Thr Pro Phe Leu Tyr Asp Leu Val Ile Thr His Ala Leu Glu Trp Pro Ser Leu Thr Val Glu 35 40 45

Trp Leu Pro Asp Arg Glu Glu Pro Ser Gly Lys Asp Tyr Ser Val Gln Lys Met Ile Leu Gly Thr His Thr Ser Glu Ser Glu Pro Asn Tyr Leu Met Leu Ala Gln Val Gln Leu Pro Leu Asp Asp Thr Glu Ser Glu Ala Arg Gln Tyr Asp Asp Asp Arg Ser Glu Phe Gly Gly Phe Gly Cys Ala Thr Gly Lys Val Gln Ile Ile Gln Gln Ile Asn His Asp Gly Glu Val Asn Arg Ala Arg Tyr Met Pro Gln Asn Pro Phe Ile Ile Ala Thr Lys Thr Val Asn Ala Glu Val Tyr Val Phe Asp Tyr Ser Lys His Pro Ser Lys Pro Pro Leu Asp Gly Ala Cys Asn Pro Asp Leu Lys Leu Arg Gly

-368 His Ser Ser Glu Gly Tyr Gly Leu Ser Trp Ser Lys Phe Lys Gln Gly 180 185 190

His Leu Leu Ser Gly Ser Asp Asp Ala Gln Ile Cys Leu Trp Asp Ile 195 200 205

* Asn Ala Thr Pro Lys Asn Lys Ser Leu Asp Ala Gln Gln Ile Phe Lys 210 215 220

Ala His Glu Gly Val Val Glu Asp Val Ala Trp His Leu Arg His Glu 225 230 235 240

Tyr Leu Phe Gly Ser Val Gly Asp Asp Gln Tyr Leu Leu Ile Trp Asp 245 250 255

Leu Arg Ser Pro Ser Ala Ser Lys Pro Val Gln Ser Val Val Ala His 260 265 270

Ser Met Glu Val Asn Cys Leu Ala Phe Asn Pro Phe Asn Glu Trp Val 275 280 285

Val Ala Thr Gly Ser Thr Asp Lys Thr Val Lys Leu Phe Asp Leu Arg 290 295 300

Lys Leu Ser Thr Ala Leu His Thr Phe Asp Ser His Lys Glu Glu Val 305 310 315 320

Phe Gln Val Gly Trp Asn Pro Lys Asn Glu Thr Ile Leu Ala Ser Cys 325 330 335

Cys Leu Gly Arg Arg Leu Met Val Trp Asp Leu Ser Arg Ile Asp Glu 340 345 350

Glu Gln Thr Val Glu Asp Ala Glu Asp Gly Pro Pro Glu Leu Leu Phe 355 360 365

Ile His Gly Gly His Thr Ser Lys Ile Ser Asp Phe Ser Trp Asn Pro 370 375 380

-369 Cys Glu Asp Trp Val Ile Ser Ser Val Ala Glu Asp Asn Ile Leu Gln 385 390 395 400

Ile Trp Gin Met Ala Glu Asn Ile Tyr His Asp Glu Asp Asp Ala Pro 405 410 415

Gly Glu Glu Pro Ser Lys Ala Ser <210> 95

<211> 18

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc feature <222> (1)..(18)

<223> n= a, t, g, or c <400> 95

ngUtgwgnat wtegwgnt <210> 96

<211> 16

<212> DNA

-370 <213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(16)

<223> n= a, t, g or c <400> 96

ngtagaswga nawgaa <210> 97

<211> 16

<212> DNA

<213> artificial sequence <220, <223> primer <220> <221> misc_feature <222> (1)..(16)

<223> n= a, t, g or c <400> 97

tgwgnagsan casaga

-371 <210> 98

<211> 16

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(16)

<223> n= a, t, g, or c <400> 98

agwgnagwan cawagg <210> 99

<211> 16

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature

-372 <222> (1)..(17)

<223> n= a,t, g or c <220> <221> misc_feature <222> (1)..(16)

<223> n= a,t, g or c <400> 99

sttgntastn ctntgc <210> 100

<211> 15

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(15)

<223> n= a, t, g or c <400> 100

ntagastwts gwgtt

-373 <210> 101

<211> 16

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(16)

<223> n= a, t, g or c <400> 101

wgtgnagwan canaga <210> 102

<211> 30

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(30)

<223>

-374 <400> 102

actagctcta ccgtttccgt ttccgtttac <210> 103

<211> 30

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> miss feature <222> (1)..(30)

<223> <400> 103

ttacatcggg ttagaaatag atcgggataa <210> 104

<211> 33

<212> DNA

<213> artificial sequence <220> <223> primer

-375 <220> <221> misc_feature <222> (1)..(33)

<223> <400> 104

aaaatagght atacgataac ggtcggtacg gga <210> 105

<211> 36

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(36)

<223> <400> 105

gggtattgcg gatatgaata taLghtUtca tgUgtg <210> 106

<211> 37

-376 <212> DNA

c213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(37)

<223> <400> 106

tacagaagaa aaataccggt tcccgtccga tEtcgac <210> 107

<211> 34

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_featrue <222> (1)..(34)

<223> <400> 107

-377 ggatcgtatc ggtUttcgat taccgtatEt atcc <210> 108

<211> 29

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc feature <222> (1)..(29)

<223> <400> 108

attaggoacc ccaggcthta cactUtatg <210> 109

<211> 30

<212> DNA

<213> artificial sequence <220> <223> primer <220>

-378 <221> misc_feature <222> (1)..(30)

<223> <400> 109

gtatgttgtg tggaattgtg agcggataac <210> 110

<211> 30

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(30)

<223> <400> 110

taacaatttc acacaggaaa cagatatgac <210> 111

<211> 34

<212> DNA

<213> artificial sequence

-379 <220> <223> primer <220> <221> misc_feature <222> (1)..(34)

<223> <400> 111

tagcatatga atttcataac caatatcgat acac <210> 112

<211> 34

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(34)

<223> <400> 112

gathactatt atatattcac aaattaccaa taca

-380 <210> 113

<211> 34

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(34)

<223> <400> 113

gccUtthcag aaatggataa atagccttgc ttcc <210> 114

<211> 32

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(32)

<223>

-381 <400> 114

caaactagga taaattatcg cgcgcggtgt ca <210> 115

<211> 32

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc feature <222> (1)..(32)

<223> <400> 115

ggUgtcatct aLgttactag atcgggaatt ga <210> 116

<211> 30

<212> DNA

<213> artificial sequence <220> <223> primer

-382 <220> <221> misc feature <222> (1)..(30)

<223> <400> 116

cgccatggoa tatgctagca tgoataattc <210> 117

<211> 35

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(35)

<223> <400> 117

aattggLaat tactatEtat tUtcatccat attga <210> 118

<211> 31

-383 <212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222> (1)..(31)

<223> <400> 118

atattgacca tcatactcat tgatgatcca t <210> 119

<211> 28

<212> DNA

<213> artificial sequence <220> <223> primer <220> <221> misc_feature <222, (1)..(28)

<223> <400, 119

-384 tgatccatgt agatttcccg gacatgaa

Claims (1)

1. - 385 CLAIMS

   1. A method of identifying a herbicidal compound, comprising: a) combining a polypeptide comprising an amino acid sequence at least 90% 5 identical to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94 with a compound to be tested for the ability to bind to said polypeptide, under conditions conducive to binding; b) selecting a compound identified in (a) that binds to said polypeptide; c) applying a compound selected in (b) to a plant to test for herbicidal activity; lo and d) selecting a compound identified in (c) that has herbicidal activity.

   2. The method according to statement 1, wherein said polypeptide comprises an

   amino acid sequence at least 95% identical to an amino acid sequence selected from the 15 group consisting of the even numbered SEQ ID NOs:294.

   3. The method according to statement 2, wherein said polypeptide comprises an

   amino acid sequence at least 99% identical to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94.

   4. The method according to statement 3, wherein said polypeptide comprises an

   amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94. 25 5. A method of identifying a herbicidal compound, comprising: a) combining a polypeptide comprising an amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94 with a compound to be tested for the ability to inhibit the activity of said polypeptide, under conditions conducive 30 to inhibition; b) selecting a compound identified in (a) that inhibits the activity of said polypeptide;

   - 386 c) applying a compound selected in (b) to a plant to test for herbicidal activity; and d) selecting a compound identified in (c) that has herbicidal activity.

   5 6. The method according to statement 5, wherein said polypeptide comprises an

   amino acid sequence at least 95% identical to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94.

   7. The method according to statement 6, wherein said polypeptide comprises an

   10 amino acid sequence at least 99% identical to an amino acid sequence selected from the group consisting of the even numbered SEQ ID NOs:2-94.

   8. The method according to statement 7, wherein said polypeptide comprises an

   amino acid sequence selected from the group consisting of the even numbered SEQ ID 15 NOs:2-94. 9. A method for killing or inhibiting the growth or viability of a plant, comprising applying to the plant a herbicidal compound identified according to the method of statement 1.

   10. A method for killing or inhibiting the growth or viability of a plant, comprising applying to the plant a herbicidal compound identified according to the method of statement 5.