HUP0003626A2 - Gyógyszerkészítmény diabetes kezelésére dioxo-tiazolidinnel, inzulin secretagogummal és alfa-glükozidáz inhibitorral - Google Patents

Gyógyszerkészítmény diabetes kezelésére dioxo-tiazolidinnel, inzulin secretagogummal és alfa-glükozidáz inhibitorral

Info

Publication number
HUP0003626A2
HUP0003626A2 HU0003626A HUP0003626A HUP0003626A2 HU P0003626 A2 HUP0003626 A2 HU P0003626A2 HU 0003626 A HU0003626 A HU 0003626A HU P0003626 A HUP0003626 A HU P0003626A HU P0003626 A2 HUP0003626 A2 HU P0003626A2
Authority
HU
Hungary
Prior art keywords
diabetes
alpha
treatment
glucocidase
thiazolidinedione
Prior art date
Application number
HU0003626A
Other languages
English (en)
Inventor
Robin Edwin Buckingham
Stephen Alistair Smith
Original Assignee
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.
Publication of HUP0003626A2 publication Critical patent/HUP0003626A2/hu
Publication of HUP0003626A3 publication Critical patent/HUP0003626A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

A találmány diabetes mellitus, különösen II. típusú diabetes, valamintdiabetes mellitusszal kapcsolatos állapotok emlősökben végzettkezelési eljárására vonatkozik, amelynek során egy ilyen kezeléstigénylő emlősnek beadják egy inzulin szenzibilizátor, egy inzulinsecretagogum és egy alfa-glükozidáz inhibitor anti-hyperglykaemiáshatóanyag hatásos, nemtoxikus és gyógyászatilag elfogadhatómennyiségét. A találmány kiterjed az említett hatóanyagokat tartalmazógyógyszerkészítményekre is. Ó
HU0003626A 1997-07-18 1998-07-16 Pharmaceutical composition for treatment of diabetes with thiazolidinedione, insulin secretagogue and alpha glucocidase inhibitor HUP0003626A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9715298A GB9715298D0 (en) 1997-07-18 1997-07-18 Novel method of treatment
PCT/GB1998/002112 WO1999003478A1 (en) 1997-07-18 1998-07-16 Treatment of diabetes with thiazolidinedione, insulin secretagogue and alpha glucocidase inhibitor

Publications (2)

Publication Number Publication Date
HUP0003626A2 true HUP0003626A2 (hu) 2001-05-28
HUP0003626A3 HUP0003626A3 (en) 2001-12-28

Family

ID=10816170

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003626A HUP0003626A3 (en) 1997-07-18 1998-07-16 Pharmaceutical composition for treatment of diabetes with thiazolidinedione, insulin secretagogue and alpha glucocidase inhibitor

Country Status (27)

Country Link
EP (1) EP1001784A1 (hu)
JP (1) JP2001510160A (hu)
KR (1) KR20010021952A (hu)
CN (1) CN1263467A (hu)
AP (1) AP2000001735A0 (hu)
AR (2) AR016350A1 (hu)
AU (1) AU8449098A (hu)
BG (1) BG104062A (hu)
BR (1) BR9810292A (hu)
CA (1) CA2297133A1 (hu)
CO (1) CO4940489A1 (hu)
DZ (1) DZ2563A1 (hu)
EA (1) EA200000140A1 (hu)
GB (1) GB9715298D0 (hu)
HU (1) HUP0003626A3 (hu)
ID (1) ID23804A (hu)
IL (1) IL133907A0 (hu)
MA (1) MA24608A1 (hu)
NO (1) NO20000230D0 (hu)
OA (1) OA11312A (hu)
PE (1) PE99499A1 (hu)
PL (1) PL338140A1 (hu)
SK (1) SK612000A3 (hu)
TR (1) TR200000133T2 (hu)
UY (1) UY25101A1 (hu)
WO (1) WO1999003478A1 (hu)
ZA (1) ZA986364B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
DK1133312T3 (da) * 1999-06-21 2008-01-02 Lilly Co Eli Synergistisk anvendelse af thiazolidindioner med glucagonlignende peptid-1 og agonister deraf til behandling af ikke-insulinafhængig diabetes
EP1741447B1 (en) * 2000-01-21 2013-09-18 Novartis AG Combinations comprising dipeptidylpeptidase-IV inhibitors and antidiabetic agents
JP4917712B2 (ja) * 2000-02-24 2012-04-18 武田薬品工業株式会社 併用医薬
US20030040490A1 (en) * 2000-02-24 2003-02-27 Yasuo Sugiyama Drugs containing combined active ingredients
US7964216B2 (en) 2001-01-12 2011-06-21 Sun Pharma Advanced Research Company Limited Spaced drug delivery system
FR2832930A1 (fr) * 2001-12-03 2003-06-06 Lipha Composition pharmaceutique comprenant un inhibiteur d'alpha-glucosidase et un derive de thiazolidinedione et son utilisation pour la preparation de medicaments destines a traiter le diabete
NZ546337A (en) 2003-10-31 2009-03-31 Takeda Pharmaceutical Solid preparation comprising an insulin sensitizer such as pioglitazone hydrochloride, an insulin secretagogue such as glimepiride and a polyoxyethylene sorbitan fatty acid ester such as Polysorbate 80
CN101103993B (zh) * 2006-07-14 2011-03-30 北京华安佛医药研究中心有限公司 降糖药物组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0601001T3 (da) * 1991-08-26 1997-10-20 Upjohn Co Flydende næringsmiddelprodukt indeholdende 3-guanidinopropionsyre.
US5917052A (en) * 1994-09-28 1999-06-29 Shaman Pharmaceuticals, Inc. Hypoglycemic agent from cryptolepis
TWI238064B (en) * 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes

Also Published As

Publication number Publication date
CN1263467A (zh) 2000-08-16
BR9810292A (pt) 2000-09-19
CA2297133A1 (en) 1999-01-28
MA24608A1 (fr) 1999-04-01
IL133907A0 (en) 2001-04-30
DZ2563A1 (fr) 2003-02-15
SK612000A3 (en) 2000-07-11
WO1999003478A1 (en) 1999-01-28
EP1001784A1 (en) 2000-05-24
NO20000230L (no) 2000-01-17
EA200000140A1 (ru) 2000-06-26
BG104062A (en) 2000-11-30
AP2000001735A0 (en) 2000-01-16
ZA986364B (en) 2000-01-17
GB9715298D0 (en) 1997-09-24
NO20000230D0 (no) 2000-01-17
ID23804A (id) 2000-05-11
KR20010021952A (ko) 2001-03-15
UY25101A1 (es) 2000-12-29
PL338140A1 (en) 2000-09-25
PE99499A1 (es) 1999-12-18
AU8449098A (en) 1999-02-10
CO4940489A1 (es) 2000-07-24
AR019724A2 (es) 2002-03-13
OA11312A (en) 2003-10-24
AR016350A1 (es) 2001-07-04
TR200000133T2 (tr) 2000-09-21
HUP0003626A3 (en) 2001-12-28
JP2001510160A (ja) 2001-07-31

Similar Documents

Publication Publication Date Title
HUP0301194A2 (hu) Dipeptidil-peptidáz IV. inhibitorokból és más antidiabetikus szerekből álló kombinációs készítmények és alkalmazásuk diabetes mellitus kezelésére
HUP0003629A2 (hu) Szinergista gyógyszerkészítmény diabetes kezelésére amely dioxo-tiazolidint, inzulin secretagogot és diguanidint tartalmaz
HUP0002373A2 (hu) Glükagon antagonisták/inverz agonisták és ezeket tartalmazó gyógyászati készítmények
EA200000041A1 (ru) Способ лечения диабета тиазолидиндионом и метформином
DE69132688T2 (de) Methode zur behandlung und vorbeugung von typ-1 diabetis durch orale verabreichung von insulin
ATE31625T1 (de) Pharmazeutisches mittel zur behandlung des diabetes mellitus.
DE69930739D1 (de) Transdermale verwendung von sekretin zur behandlung von autismus
HUP0104108A2 (hu) Eljárás diabétesz kezelésére egy aP2 inhibitor vagy kombinációja alkalmazásával
KR890005147A (ko) 펩티딜헤테로사이클
PT969843E (pt) Composicoes antitussicas contendo teobromina
HUP0003260A2 (hu) Gyógyszerkészítmény diabetes kezelésére rosziglitazonnal és inzulinnal
HUP0003626A2 (hu) Gyógyszerkészítmény diabetes kezelésére dioxo-tiazolidinnel, inzulin secretagogummal és alfa-glükozidáz inhibitorral
ES2122015T3 (es) Uso de urodilatina en enfermedades pulmonares y bronquiales.
KR950703353A (ko) 인슐린-의존적 진성 당뇨병을 예방 또는 치료하기 위한 인터루킨-10의 용도(Use of IL-10 to prevent or treat insulin-dependent diabetes mellitus)
EP0482089A4 (en) Methods of treating or preventing autoimmune uveoretinitis in mammals
HUP0003634A2 (hu) Dioxo-tiazolidin-származékok és szulfonil-karbamid-származékok alkalmazása diabetes kezelésére szolgáló gyógyszerkészítmények előállítására
HUP0104388A2 (hu) Béta-agonistákból és további antidiabetikus szerekből álló kombinációk
DE69822810D1 (de) Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x
NO996270L (no) Behandling av diabetes med tiazolidindion og <alfa>- glukosidaseinhibitor
KR880004810A (ko) 소화성 궤양 치료제
HUP0003673A2 (hu) Dioxo-tiazolidinek alkalmazása a hyperglykaemia kezelésére
HUP0003922A2 (hu) Dioxo-tiazolidinek alkalmazása a hyperglykaemia kezelésére
RU96115219A (ru) Способ лечения больных сахарным диабетом
MX9701529A (es) Uso de (e)-1-[4'-(2-alquilaminoetoxi)fenil]-1-(3'-hidroxifenil)-2-f enilbut-1-enos para inhibir trastornos patologicos.
MX9701528A (es) Derivados de 1, 1, 2,- trifenilbut-1-eno para tratar la enfermedad de alzheimer.