DE69822810D1 - Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x - Google Patents

Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x

Info

Publication number
DE69822810D1
DE69822810D1 DE69822810T DE69822810T DE69822810D1 DE 69822810 D1 DE69822810 D1 DE 69822810D1 DE 69822810 T DE69822810 T DE 69822810T DE 69822810 T DE69822810 T DE 69822810T DE 69822810 D1 DE69822810 D1 DE 69822810D1
Authority
DE
Germany
Prior art keywords
somatostatin
syndrome
agoniste
treatment
insulin sensitivity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69822810T
Other languages
English (en)
Other versions
DE69822810T2 (de
Inventor
Anthony Cawthorne
Yong-Ling Liu
V Sennitt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Application granted granted Critical
Publication of DE69822810D1 publication Critical patent/DE69822810D1/de
Publication of DE69822810T2 publication Critical patent/DE69822810T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE69822810T 1997-05-13 1998-05-13 Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x Expired - Lifetime DE69822810T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85494397A 1997-05-13 1997-05-13
US854943 1997-05-13
PCT/EP1998/003000 WO1998051332A1 (en) 1997-05-13 1998-05-13 Somatostatin and somatostatin agonists for treating insulin insensitivity and syndrome x

Publications (2)

Publication Number Publication Date
DE69822810D1 true DE69822810D1 (de) 2004-05-06
DE69822810T2 DE69822810T2 (de) 2005-02-03

Family

ID=25319948

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69822810T Expired - Lifetime DE69822810T2 (de) 1997-05-13 1998-05-13 Somatostatin und somatostatin agoniste zur behandlung der insulinsunempfindlichkeit und syndrome x

Country Status (11)

Country Link
US (2) US7256174B2 (de)
EP (1) EP0980253B1 (de)
AT (1) ATE262921T1 (de)
AU (1) AU8019898A (de)
CA (1) CA2289499C (de)
DE (1) DE69822810T2 (de)
DK (1) DK0980253T3 (de)
ES (1) ES2216290T3 (de)
HK (1) HK1026843A1 (de)
PT (1) PT980253E (de)
WO (1) WO1998051332A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2199355A1 (en) 1997-03-06 1998-09-06 Bob Bishop Multiple beam laser welding apparatus
CA2334945A1 (en) * 1998-06-12 1999-12-16 Christophe Alain Thurieau Imidazolyl derivatives
EP1291022A1 (de) * 1998-07-30 2003-03-12 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Anwendungsverfahren für lanreotid, ein somatostatin analogon
BR9912609A (pt) * 1998-07-30 2001-05-02 Sod Conseils Rech Applic Métodos de uso de um análogo de somatostatina
US6150333A (en) * 1998-07-30 2000-11-21 Biomeasure, Inc. Methods of using a somatostatin analogue
US6903074B1 (en) 1999-06-04 2005-06-07 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Neuromedin b and somatostatin receptor agonists
BR0011680A (pt) * 1999-06-04 2002-04-30 Sod Conseils Rech Applic Agonistas receptores de somatostatina neuromedina b, seu uso e composição farmacêutica compreendendo os mesmos
CZ20014534A3 (cs) * 1999-06-25 2002-06-12 Societe De Conseils De Recherches Et D´Applic Atio Peptid, farmaceutický prostředek a způsob
US6864234B1 (en) 1999-06-25 2005-03-08 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Somatostatin agonists
US20070275382A1 (en) * 2003-11-25 2007-11-29 Muriel Saulnier Biomarkers for the Efficacy of Somatostatin Analogue Treatment

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291022A (en) 1975-03-11 1981-09-22 Sandoz Ltd. Organic compounds
US4133782A (en) 1976-06-07 1979-01-09 The Salk Institute For Biological Studies Somatostatin analogs with dissociated biological activities
US4190575A (en) 1977-12-27 1980-02-26 American Home Products Corporation Polypeptides related to somatostatin
IE47421B1 (en) 1977-06-08 1984-03-07 Merck & Co Inc Somatostatin analogs,process for their preparation and pharmaceutical compositions containing them
US4211693A (en) 1977-09-20 1980-07-08 The Salk Institute For Biological Studies Peptides with para-substituted phenylalanine
LU78191A1 (de) 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden
CA1107273A (en) 1978-05-19 1981-08-18 Chester A. Meyers Somatostatin analogs having a substituted tryptophyl residue in position eight
JPS5819669B2 (ja) 1978-10-28 1983-04-19 白井松新薬株式会社 新規生理活性ペプチド化合物及びその製造法
US4215039A (en) 1979-02-15 1980-07-29 American Home Products Corporation Somatostatin analogues
US4190648A (en) 1979-03-13 1980-02-26 Merck & Co., Inc. Peptides having somatostatin activity
US4316890A (en) 1979-03-16 1982-02-23 Ciba-Geigy Corporation Peptides and processes for the manufacture thereof
US4209426A (en) 1979-05-29 1980-06-24 American Home Products Corporation Polypeptides related to somatostatin
US4328214A (en) 1979-07-04 1982-05-04 Ciba-Geigy Corporation Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture
US4310518A (en) 1979-10-31 1982-01-12 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US4235886A (en) 1979-10-31 1980-11-25 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
DE19375086I2 (de) 1979-11-27 2003-01-09 Novartis Ag Polypeptide Verfahren zu ihrer Herstellung pharmazeutische Zusammensetzungen die diese Polypeptide enthalten und ihre Verwendung
US4369179A (en) 1979-12-14 1983-01-18 Ciba-Geigy Corporation Acylpeptides
DD155985A5 (de) 1979-12-21 1982-07-21 Ciba Geigy Ag Verfahren zur herstellung cyclischr octapeptide
US4282143A (en) 1980-06-13 1981-08-04 American Home Products Corporation Octapeptides lowering growth hormone
DK81082A (da) 1981-03-06 1982-09-07 Sandoz Ag Fremgangsmaade til fremstilling af polypeptider
US4360516A (en) 1981-04-13 1982-11-23 Merck & Co., Inc. Modified D-retro cyclic hexapeptide somatostatin analogs
EP0083305B1 (de) 1981-12-24 1985-07-10 Ciba-Geigy Ag Cyclische Octapeptide und pharmazeutische Präparate davon, sowie Verfahren zur Herstellung derselben und ihre Anwendung
US4476415A (en) * 1982-08-20 1984-10-09 Johnson Service Company Feedback transducer
US4486415A (en) 1983-08-15 1984-12-04 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US4485101A (en) 1983-10-11 1984-11-27 Administrators Of The Tulane Educational Fund Peptides
US4522813A (en) 1983-10-27 1985-06-11 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
US4684620A (en) 1984-09-04 1987-08-04 Gibson-Stephens Neuropharmaceuticals, Inc. Cyclic polypeptides having mu-receptor specificity
HUT42101A (en) 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
US4725577A (en) 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
US4650787A (en) 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides
US4585755A (en) 1985-04-29 1986-04-29 Merck & Co., Inc. Cyclic and bridged cyclic somatostatin analogs useful as local anti-inflammatory agents
US4904642A (en) 1985-09-12 1990-02-27 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
US4853371A (en) 1986-06-17 1989-08-01 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
US4871717A (en) 1987-01-07 1989-10-03 Administrators Of The Tulane Educational Fund Peptides
DK375789A (da) * 1988-08-18 1990-02-19 Syntex Inc Peptidderivater
HUT59166A (en) 1989-12-08 1992-04-28 Univ Tulane Process for producing octqpeptide somatostatine analogues with treonine at the 6 position and pharmaceutical compositions containing them
US5583104A (en) * 1993-12-06 1996-12-10 Mayo Foundation For Medical Research And Education Treatment of proliferation of bile duct epithelium
US5763200A (en) 1995-05-12 1998-06-09 Biomeasure, Incorporated Inhibition of amylin release
US5708135A (en) 1995-09-29 1998-01-13 Biomeasure Incorporated Cyclic peptide analogs of somatostatin
US5686418A (en) 1996-04-08 1997-11-11 Biomeasure Incorporated Prolonging survival of transplanted pancreatic cells
AU4133997A (en) * 1996-09-12 1998-04-02 Yarom Cohen Pharmaceutical composition for the treatment of syndrome x of reaven

Also Published As

Publication number Publication date
DE69822810T2 (de) 2005-02-03
EP0980253A1 (de) 2000-02-23
CA2289499A1 (en) 1998-11-19
ATE262921T1 (de) 2004-04-15
EP0980253B1 (de) 2004-03-31
US20080020974A1 (en) 2008-01-24
PT980253E (pt) 2004-08-31
WO1998051332A1 (en) 1998-11-19
CA2289499C (en) 2010-02-23
DK0980253T3 (da) 2004-07-05
ES2216290T3 (es) 2004-10-16
AU8019898A (en) 1998-12-08
HK1026843A1 (en) 2000-12-29
US20040072734A1 (en) 2004-04-15
US7256174B2 (en) 2007-08-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: IPSEN PHARMA S.A.S., BOULOGNE-BILLANCOURT, FR