HUP0002719A2 - Hatásos komponensként ace (angiotenzin-konvertáz enzim)-gátló anyagot tartalmazó, szabályozott felszabadulást biztosító gyógyászati készítmény - Google Patents

Hatásos komponensként ace (angiotenzin-konvertáz enzim)-gátló anyagot tartalmazó, szabályozott felszabadulást biztosító gyógyászati készítmény

Info

Publication number
HUP0002719A2
HUP0002719A2 HU0002719A HUP0002719A HUP0002719A2 HU P0002719 A2 HUP0002719 A2 HU P0002719A2 HU 0002719 A HU0002719 A HU 0002719A HU P0002719 A HUP0002719 A HU P0002719A HU P0002719 A2 HUP0002719 A2 HU P0002719A2
Authority
HU
Hungary
Prior art keywords
active ingredient
pharmaceutical preparation
active agent
controlled release
release pharmaceutical
Prior art date
Application number
HU0002719A
Other languages
English (en)
Inventor
Wilfried Fischer
Karin Klokkers
Renate Oppelt
Original Assignee
Hexal Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexal Ag filed Critical Hexal Ag
Publication of HUP0002719A2 publication Critical patent/HUP0002719A2/hu
Publication of HUP0002719A3 publication Critical patent/HUP0002719A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgya olyan gyógyászati készítmény, amely az alábbikomponenseket tartalmazza vagy azokból áll: (i) egy hatóanyag kezdetiadagját, amely a hatóanyagot szolgáltatja tetszőleges (adott esetbenjelen lévő) segédanyagokkal együtt; (ii) egy első típusú, késleltetettfelszabadulású pellet, amelyben a hatóanyagot és a tetszőlegessegédanyagokat egy bevonat burkolja; és (iii) egy második típusú,késleltetett felszabadulású pellet, amelyben a hatóanyagot és atetszőleges segédanyagokat ismét egy másik bevonat burkolja; - ahol ahatóanyag valamilyen ACE (angiotenzin-konvertáz enzim)-gátló anyag; és- ahol az (ii) és (iii) burkolatainak a mennyiségei (tömegalapon) 1 :2 -től 1 : 7-ig terjedő tömegarányban vannak jelen. Ó
HU0002719A 1997-06-12 1998-06-12 Controlled release pharmaceutical preparation with ace inhibitor as active agent HUP0002719A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19724696A DE19724696A1 (de) 1997-06-12 1997-06-12 Pharmazeutische Zubereitung mit drei Pelletarten

Publications (2)

Publication Number Publication Date
HUP0002719A2 true HUP0002719A2 (hu) 2000-12-28
HUP0002719A3 HUP0002719A3 (en) 2001-04-28

Family

ID=7832182

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0002719A HUP0002719A3 (en) 1997-06-12 1998-06-12 Controlled release pharmaceutical preparation with ace inhibitor as active agent

Country Status (19)

Country Link
US (1) US6267990B1 (hu)
EP (1) EP0994696B1 (hu)
JP (1) JP2002504108A (hu)
CN (1) CN1260714A (hu)
AT (1) ATE259637T1 (hu)
AU (1) AU736357B2 (hu)
CA (1) CA2295013A1 (hu)
DE (2) DE19724696A1 (hu)
DK (1) DK0994696T3 (hu)
ES (1) ES2216296T3 (hu)
HU (1) HUP0002719A3 (hu)
IL (1) IL133442A0 (hu)
NO (1) NO996049L (hu)
NZ (1) NZ501726A (hu)
PL (1) PL192648B1 (hu)
SK (1) SK169999A3 (hu)
TR (1) TR199903069T2 (hu)
WO (1) WO1998056355A1 (hu)
ZA (1) ZA985142B (hu)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4446463B2 (ja) * 2000-10-16 2010-04-07 第一三共株式会社 口腔内速崩壊性医薬組成物およびその製造方法
FR2818550B1 (fr) * 2000-12-26 2003-02-07 Servier Lab Composition pharmaceutique solide thermoformable pour la liberation controle de perindopril
ES2322896T3 (es) * 2002-04-29 2009-07-01 Supernus Pharmaceuticals, Inc. Formulaciones farmaceuticas con biodisponibilidad mejorada.
FR2841140B1 (fr) 2002-06-24 2004-10-01 Servier Lab Microcapsules pour la liberation retardee et controlee du perindopril
ATE482694T1 (de) * 2002-07-05 2010-10-15 Temrel Ltd Zusammensetzung zur kontrollierten wirkstoffabgabe
WO2005046684A1 (en) 2003-11-04 2005-05-26 Shire Laboratories, Inc. Once daily dosage forms of trospium
CA2536401C (en) 2003-11-04 2011-08-30 Shire Laboratories Inc. Compositions of quaternary ammonium compounds containing bioavailability enhancers
US20050203168A1 (en) * 2004-03-11 2005-09-15 The Regents Of The University Of Michigan Angiotensin converting enzyme inhibitor use for treatment and prevention of gastrointestinal disorders
ATE493973T1 (de) 2004-06-04 2011-01-15 Teva Pharma Irbesartan enthaltende pharmazeutische zusammensetzung
KR100593795B1 (ko) 2004-10-12 2006-06-30 대원제약주식회사 안정성이 개선된 라미프릴을 포함하는 경구투여용 제제
US8080579B2 (en) * 2005-10-03 2011-12-20 The Regents Of The University Of Michigan Compositions and methods for treatment of inflammatory bowel disease
US7731604B2 (en) * 2006-10-31 2010-06-08 Taylor Made Golf Company, Inc. Golf club iron head
CN102112115A (zh) * 2008-07-30 2011-06-29 万能药生物有限公司 雷米普利调节释放组合物及其应用
CA2959186C (en) 2014-09-19 2020-03-24 The Procter & Gamble Company Pulsed release phenylephrine dosage forms
US10278930B2 (en) 2017-03-16 2019-05-07 The Procter & Gamble Company Method for relieving sinus congestion

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2836447A1 (de) * 1978-08-19 1980-02-28 Boehringer Sohn Ingelheim Neue bunitrolol-retardform
US4728512A (en) * 1985-05-06 1988-03-01 American Home Products Corporation Formulations providing three distinct releases
AU591248B2 (en) * 1986-03-27 1989-11-30 Kinaform Technology, Inc. Sustained-release pharaceutical preparation
US5158777A (en) * 1990-02-16 1992-10-27 E. R. Squibb & Sons, Inc. Captopril formulation providing increased duration of activity
US5326570A (en) * 1991-07-23 1994-07-05 Pharmavene, Inc. Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
US5876754A (en) * 1992-01-17 1999-03-02 Alfatec-Pharma Gmbh Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
DE4431832A1 (de) * 1994-09-07 1996-03-14 Cordes Guenter Dr Arzneimittelzubereitung für ACE-Hemmer
DE19511131A1 (de) * 1995-03-27 1996-10-02 Basf Ag Mechanisch stabile feste Wirkstoffzubereitungsformen

Also Published As

Publication number Publication date
ATE259637T1 (de) 2004-03-15
NO996049L (no) 2000-02-07
EP0994696A1 (de) 2000-04-26
ZA985142B (en) 2000-01-12
HUP0002719A3 (en) 2001-04-28
EP0994696B1 (de) 2004-02-18
WO1998056355A1 (de) 1998-12-17
TR199903069T2 (xx) 2000-05-22
DE59810803D1 (de) 2004-03-25
AU736357B2 (en) 2001-07-26
DK0994696T3 (da) 2004-06-01
PL337279A1 (en) 2000-08-14
NO996049D0 (no) 1999-12-08
CN1260714A (zh) 2000-07-19
US6267990B1 (en) 2001-07-31
PL192648B1 (pl) 2006-11-30
DE19724696A1 (de) 1998-12-24
NZ501726A (en) 2001-09-28
SK169999A3 (en) 2000-07-11
JP2002504108A (ja) 2002-02-05
CA2295013A1 (en) 1998-12-17
IL133442A0 (en) 2001-04-30
AU8336898A (en) 1998-12-30
ES2216296T3 (es) 2004-10-16

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