HUP0001823A2 - Kémiailag állandó és hőstabil norastemizol készítmények - Google Patents

Kémiailag állandó és hőstabil norastemizol készítmények

Info

Publication number
HUP0001823A2
HUP0001823A2 HU0001823A HUP0001823A HUP0001823A2 HU P0001823 A2 HUP0001823 A2 HU P0001823A2 HU 0001823 A HU0001823 A HU 0001823A HU P0001823 A HUP0001823 A HU P0001823A HU P0001823 A2 HUP0001823 A2 HU P0001823A2
Authority
HU
Hungary
Prior art keywords
norastemizole
chemically
thermally stable
stable
formulations
Prior art date
Application number
HU0001823A
Other languages
English (en)
Inventor
Hal T. Butler
Martin P. Redmon
Stephen A. Wald
Original Assignee
Sepracor Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc. filed Critical Sepracor Inc.
Publication of HUP0001823A2 publication Critical patent/HUP0001823A2/hu
Publication of HUP0001823A3 publication Critical patent/HUP0001823A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A jelen találmány tárgyát a hatékony antihisztamin, a norastemizolkémiailag állandó és hőstabil gyógyszerkészítményei képezik. Akészítmények laktózmentes, nem higroszkópos vagy vízmentes, vagy nagyszemcsés, vagy inert módon bevont norastemizolból vagygyógyszerészetileg elfogadható norastemizolsóból állnak, stabilak éselőállításuk egyszerű. Ó
HU0001823A 1997-03-26 1998-03-25 Chemically and thermally stable norastemizole formulations HUP0001823A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82447797A 1997-03-26 1997-03-26
US85178697A 1997-05-06 1997-05-06
PCT/US1998/005701 WO1998042379A2 (en) 1997-03-26 1998-03-25 Chemically and thermally stable norastemizole formulations

Publications (2)

Publication Number Publication Date
HUP0001823A2 true HUP0001823A2 (hu) 2001-04-28
HUP0001823A3 HUP0001823A3 (en) 2002-04-29

Family

ID=27124816

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001823A HUP0001823A3 (en) 1997-03-26 1998-03-25 Chemically and thermally stable norastemizole formulations

Country Status (13)

Country Link
EP (1) EP1035869A1 (hu)
JP (1) JP2002512614A (hu)
KR (1) KR20010005746A (hu)
CN (1) CN1257431A (hu)
AR (1) AR012187A1 (hu)
BR (1) BR9808428A (hu)
CA (1) CA2284705A1 (hu)
HU (1) HUP0001823A3 (hu)
NO (1) NO994655L (hu)
NZ (3) NZ517472A (hu)
RU (1) RU2214245C2 (hu)
WO (1) WO1998042379A2 (hu)
ZA (1) ZA982562B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ289261B6 (cs) 2000-07-11 2001-12-12 Léčiva, A.S. Tableta vyrobitelná přímým tabletováním, obsahující aktivní látku kyselinu 4-amino-1-hydroxybutyliden-1,1-bisfosfonovou, a způsob její výroby
EP2201982A1 (en) * 2008-12-24 2010-06-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Histamine H4 receptor antagonists for the treatment of vestibular disorders
EA201270309A1 (ru) * 2009-08-24 2012-07-30 Абды Ибрахым Иладж Санайи Ве Тыджарет Аноным Сыркеты Таблетки отилония, полученные прямым прессованием

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3781173T2 (de) * 1986-02-03 1992-12-17 Janssen Pharmaceutica Nv N-heterozyklische-4-piperidinamine enthaltende anti-histaminische zusammensetzungen.
DE4037426A1 (de) * 1990-11-24 1992-05-27 Kali Chemie Pharma Gmbh Piperidinoalkylbenzoxazin- und -thiazin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE4394931T1 (de) * 1992-09-03 1995-07-20 Sepracor Inc Verwendung von Norastemizol zur Behandlung von allergischen Erkrankungen
PT920425E (pt) * 1995-11-17 2003-07-31 Aventis Pharma Inc 4-(1h-benzimidazol-2-il-amino)piperidinas substituidas uteis para o tratamento de doencas alergicas
EP0920315B1 (en) * 1996-08-16 2005-12-28 Schering Corporation Treatment of upper airway allergic responses with a combination of histamine receptor antagonists

Also Published As

Publication number Publication date
HUP0001823A3 (en) 2002-04-29
RU2214245C2 (ru) 2003-10-20
WO1998042379A3 (en) 2001-03-01
NO994655D0 (no) 1999-09-24
CN1257431A (zh) 2000-06-21
ZA982562B (en) 1998-10-01
NZ517472A (en) 2003-08-29
AU6868098A (en) 1998-10-20
EP1035869A1 (en) 2000-09-20
BR9808428A (pt) 2000-05-23
CA2284705A1 (en) 1998-10-01
AR012187A1 (es) 2000-09-27
NO994655L (no) 1999-11-15
AU735257B2 (en) 2001-07-05
NZ527200A (en) 2004-12-24
KR20010005746A (ko) 2001-01-15
JP2002512614A (ja) 2002-04-23
NZ527201A (en) 2004-12-24
WO1998042379A2 (en) 1998-10-01

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