ZA982562B - Chemically and thermally stable norastemizole formulations - Google Patents

Chemically and thermally stable norastemizole formulations

Info

Publication number
ZA982562B
ZA982562B ZA982562A ZA982562A ZA982562B ZA 982562 B ZA982562 B ZA 982562B ZA 982562 A ZA982562 A ZA 982562A ZA 982562 A ZA982562 A ZA 982562A ZA 982562 B ZA982562 B ZA 982562B
Authority
ZA
South Africa
Prior art keywords
chemically
thermally stable
norastemizole
formulations
norastemizole formulations
Prior art date
Application number
ZA982562A
Inventor
Martin P Redmon
Hal T Butler
Stephen A Wald
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of ZA982562B publication Critical patent/ZA982562B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA982562A 1997-03-26 1998-03-26 Chemically and thermally stable norastemizole formulations ZA982562B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82447797A 1997-03-26 1997-03-26
US85178697A 1997-05-06 1997-05-06

Publications (1)

Publication Number Publication Date
ZA982562B true ZA982562B (en) 1998-10-01

Family

ID=27124816

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA982562A ZA982562B (en) 1997-03-26 1998-03-26 Chemically and thermally stable norastemizole formulations

Country Status (13)

Country Link
EP (1) EP1035869A1 (en)
JP (1) JP2002512614A (en)
KR (1) KR20010005746A (en)
CN (1) CN1257431A (en)
AR (1) AR012187A1 (en)
BR (1) BR9808428A (en)
CA (1) CA2284705A1 (en)
HU (1) HUP0001823A3 (en)
NO (1) NO994655L (en)
NZ (3) NZ517472A (en)
RU (1) RU2214245C2 (en)
WO (1) WO1998042379A2 (en)
ZA (1) ZA982562B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20002567A3 (en) * 2000-07-11 2001-12-12 Léčiva, A.S. Tablet that can be prepared by direct tabletting containing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid as active substance and process for preparing thereof
EP2201982A1 (en) * 2008-12-24 2010-06-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Histamine H4 receptor antagonists for the treatment of vestibular disorders
EA201270309A1 (en) * 2009-08-24 2012-07-30 Абды Ибрахым Иладж Санайи Ве Тыджарет Аноным Сыркеты OTILONIA TABLETS RECEIVED BY DIRECT PRESSING

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2052544T3 (en) * 1986-02-03 1994-07-16 Janssen Pharmaceutica Nv ANTI-HISTAMINIC COMPOSITIONS CONTAINING N-HETEROCICLIL-4-PIPERIDINAMINES.
DE4037426A1 (en) * 1990-11-24 1992-05-27 Kali Chemie Pharma Gmbh PIPERIDINOALKYLBENZAZAZIN- AND -THIAZIN COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF AND THE COMPOSITIONS CONTAINING SUCH COMPOUNDS
DE69333387T2 (en) * 1992-09-03 2004-12-09 Sepracor Inc., Marlborough Pharmaceutical compositions containing norastemizole.
JPH11513991A (en) * 1995-11-17 1999-11-30 ヘキスト・マリオン・ルセル・インコーポレイテツド Substituted 4- (1H-benzimidazol-2-yl-amino) piperidines useful for treating allergic diseases
AU722040B2 (en) * 1996-08-16 2000-07-20 Schering Corporation Treatment of upper airway allergic responses with a combination of histamine receptor antagonists

Also Published As

Publication number Publication date
RU2214245C2 (en) 2003-10-20
NZ517472A (en) 2003-08-29
AU6868098A (en) 1998-10-20
AU735257B2 (en) 2001-07-05
HUP0001823A2 (en) 2001-04-28
WO1998042379A2 (en) 1998-10-01
NO994655D0 (en) 1999-09-24
CA2284705A1 (en) 1998-10-01
WO1998042379A3 (en) 2001-03-01
JP2002512614A (en) 2002-04-23
HUP0001823A3 (en) 2002-04-29
NZ527200A (en) 2004-12-24
NO994655L (en) 1999-11-15
NZ527201A (en) 2004-12-24
AR012187A1 (en) 2000-09-27
BR9808428A (en) 2000-05-23
KR20010005746A (en) 2001-01-15
EP1035869A1 (en) 2000-09-20
CN1257431A (en) 2000-06-21

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