HUP0001441A2 - Eljárás 4-aza-androszt-1-én származékokat tartalmazó gyógyszerkészítmények előállítására - Google Patents
Eljárás 4-aza-androszt-1-én származékokat tartalmazó gyógyszerkészítmények előállításáraInfo
- Publication number
- HUP0001441A2 HUP0001441A2 HU0001441A HUP0001441A HUP0001441A2 HU P0001441 A2 HUP0001441 A2 HU P0001441A2 HU 0001441 A HU0001441 A HU 0001441A HU P0001441 A HUP0001441 A HU P0001441A HU P0001441 A2 HUP0001441 A2 HU P0001441A2
- Authority
- HU
- Hungary
- Prior art keywords
- androst
- aza
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- KGGYWJVXCZVJFC-BZCFTNLBSA-N (3as,3bs,9ar,9bs,11as)-9a,11a-dimethyl-2,3,3a,3b,4,5,5a,6,7,9b,10,11-dodecahydro-1h-indeno[5,4-f]quinoline Chemical class C1CC2NCC=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 KGGYWJVXCZVJFC-BZCFTNLBSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány az (I) általános képletű vegyületek -, a képletben R1 ésR2 egymástól függetlenül hidrogénatomot, hidroxilcsoportot, védetthidroxilcsoportot vagy rövid szénláncú alkoxicsoportot jelent -, vagygyógyászatilag elfogadható sóik vagy egyéb származékaik alkalmazásáravonatkozik prosztatarák elleni gyógyászati készítmények előállítására. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4233597 | 1997-02-26 | ||
PCT/JP1998/000767 WO1998038207A1 (fr) | 1997-02-26 | 1998-02-26 | Compositions de traitement ou de prevention du cancer de la prostate |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0001441A2 true HUP0001441A2 (hu) | 2000-10-28 |
HUP0001441A3 HUP0001441A3 (en) | 2001-03-28 |
Family
ID=12633151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0001441A HUP0001441A3 (en) | 1997-02-26 | 1998-02-26 | Process for the preparation of pharmaceutical compositions containing 4-aza-androst-1-ene derivatives |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0963998B1 (hu) |
KR (1) | KR20000075651A (hu) |
CN (1) | CN1131239C (hu) |
AT (1) | ATE265854T1 (hu) |
AU (1) | AU739308B2 (hu) |
BR (1) | BR9807767A (hu) |
CA (1) | CA2282836A1 (hu) |
DE (1) | DE69823650T2 (hu) |
DK (1) | DK0963998T3 (hu) |
ES (1) | ES2221703T3 (hu) |
HK (1) | HK1023576A1 (hu) |
HU (1) | HUP0001441A3 (hu) |
ID (1) | ID22762A (hu) |
IL (1) | IL131380A0 (hu) |
NO (1) | NO994107L (hu) |
NZ (1) | NZ337048A (hu) |
PL (1) | PL335365A1 (hu) |
PT (1) | PT963998E (hu) |
RU (1) | RU2196582C2 (hu) |
WO (1) | WO1998038207A1 (hu) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0998930B1 (en) * | 1997-07-29 | 2004-03-24 | Sankyo Company Limited | Azasteroid compound for treating alopecia, hirsutism and seborrhea |
KR100698400B1 (ko) | 2004-04-14 | 2007-03-23 | 이은주 | 탈모증 및 전립선비대증 치료를 위한 약제학적 조성물 |
CA2562801C (en) | 2004-04-14 | 2010-09-07 | Eun-Joo Lee | Pharmaceutical composition for treating hair loss and benign prostatic hyperplasia |
EP1726650A1 (en) * | 2005-05-27 | 2006-11-29 | Universitätsklinikum Freiburg | Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen |
RU2695348C2 (ru) * | 2018-04-26 | 2019-07-23 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ радиологии" Минздрава России) | Способ лечения больных с наличием метастазов в лимфатических узлах и олигометастазов в костях скелета при раке предстательной железы |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8505862D0 (en) * | 1985-03-07 | 1985-04-11 | Erba Farmitalia | Steroidic 5alpha-reductase inhibitors |
IE76452B1 (en) * | 1990-10-29 | 1997-10-22 | Sankyo Co | Azasteroid compounds for the treatment of prostatic hypertrophy their preparation and use |
JPH06293793A (ja) * | 1993-02-10 | 1994-10-21 | Sankyo Co Ltd | ステロイド−17−アミド類の製造法 |
JPH0873492A (ja) * | 1994-06-28 | 1996-03-19 | Sankyo Co Ltd | アザステロイド類 |
JPH0819151A (ja) * | 1994-06-30 | 1996-01-19 | Furukawa Electric Co Ltd:The | アーマロッド巻付構造 |
CZ289856B6 (cs) * | 1996-02-05 | 2002-04-17 | Sankyo Company Limited | Farmaceutický prostředek na bázi inhibitoru 5alfa-reduktázy |
EP0998930B1 (en) * | 1997-07-29 | 2004-03-24 | Sankyo Company Limited | Azasteroid compound for treating alopecia, hirsutism and seborrhea |
-
1998
- 1998-02-26 HU HU0001441A patent/HUP0001441A3/hu unknown
- 1998-02-26 KR KR1019997007716A patent/KR20000075651A/ko not_active Application Discontinuation
- 1998-02-26 ID IDW990912A patent/ID22762A/id unknown
- 1998-02-26 PT PT98905646T patent/PT963998E/pt unknown
- 1998-02-26 CN CN98804295A patent/CN1131239C/zh not_active Expired - Fee Related
- 1998-02-26 AU AU61159/98A patent/AU739308B2/en not_active Ceased
- 1998-02-26 IL IL13138098A patent/IL131380A0/xx unknown
- 1998-02-26 RU RU99118510/14A patent/RU2196582C2/ru not_active IP Right Cessation
- 1998-02-26 DK DK98905646T patent/DK0963998T3/da active
- 1998-02-26 NZ NZ337048A patent/NZ337048A/xx unknown
- 1998-02-26 CA CA002282836A patent/CA2282836A1/en not_active Abandoned
- 1998-02-26 EP EP98905646A patent/EP0963998B1/en not_active Expired - Lifetime
- 1998-02-26 AT AT98905646T patent/ATE265854T1/de not_active IP Right Cessation
- 1998-02-26 DE DE69823650T patent/DE69823650T2/de not_active Expired - Fee Related
- 1998-02-26 ES ES98905646T patent/ES2221703T3/es not_active Expired - Lifetime
- 1998-02-26 PL PL98335365A patent/PL335365A1/xx unknown
- 1998-02-26 BR BR9807767-8A patent/BR9807767A/pt not_active IP Right Cessation
- 1998-02-26 WO PCT/JP1998/000767 patent/WO1998038207A1/ja not_active Application Discontinuation
-
1999
- 1999-08-25 NO NO994107A patent/NO994107L/no not_active Application Discontinuation
-
2000
- 2000-04-28 HK HK00102592A patent/HK1023576A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2221703T3 (es) | 2005-01-01 |
NO994107D0 (no) | 1999-08-25 |
NO994107L (no) | 1999-08-25 |
AU739308B2 (en) | 2001-10-11 |
CN1252805A (zh) | 2000-05-10 |
ID22762A (id) | 1999-12-09 |
NZ337048A (en) | 2000-10-27 |
EP0963998B1 (en) | 2004-05-06 |
CN1131239C (zh) | 2003-12-17 |
DE69823650T2 (de) | 2004-12-09 |
HUP0001441A3 (en) | 2001-03-28 |
KR20000075651A (ko) | 2000-12-26 |
WO1998038207A1 (fr) | 1998-09-03 |
DK0963998T3 (da) | 2004-08-16 |
PL335365A1 (en) | 2000-04-25 |
BR9807767A (pt) | 2000-02-22 |
EP0963998A4 (en) | 2002-06-12 |
EP0963998A1 (en) | 1999-12-15 |
CA2282836A1 (en) | 1998-09-03 |
DE69823650D1 (de) | 2004-06-09 |
IL131380A0 (en) | 2001-01-28 |
PT963998E (pt) | 2004-07-30 |
HK1023576A1 (en) | 2000-09-15 |
RU2196582C2 (ru) | 2003-01-20 |
AU6115998A (en) | 1998-09-18 |
ATE265854T1 (de) | 2004-05-15 |
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