HUP0202340A2 - Hatóanyagként kondenzált heterociklusos vegyületeket tartalmazó gyógyszerkészítmények és alkalmazásuk - Google Patents

Hatóanyagként kondenzált heterociklusos vegyületeket tartalmazó gyógyszerkészítmények és alkalmazásuk

Info

Publication number
HUP0202340A2
HUP0202340A2 HU0202340A HUP0202340A HUP0202340A2 HU P0202340 A2 HUP0202340 A2 HU P0202340A2 HU 0202340 A HU0202340 A HU 0202340A HU P0202340 A HUP0202340 A HU P0202340A HU P0202340 A2 HUP0202340 A2 HU P0202340A2
Authority
HU
Hungary
Prior art keywords
heterocyclic compounds
condensed heterocyclic
ylmethyl
optionally substituted
active ingredient
Prior art date
Application number
HU0202340A
Other languages
English (en)
Inventor
Takashi Fujita
Kosaku Fujiwara
Shinichi Kurakata
Original Assignee
Sankyo Company, Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Company, Limited filed Critical Sankyo Company, Limited
Publication of HUP0202340A2 publication Critical patent/HUP0202340A2/hu
Publication of HUP0202340A3 publication Critical patent/HUP0202340A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Az (I) általános képletű kondenzált heterociklusos vegyületek ésgyógyászatilag elfogadható sóik, melyek a rák gyógyítására ésmegelőzésére alkalmasak. Az (I) általános képletben X jelentésebenzimidazolilcsoport, mely adott esetben 1-5 szubsztituensselhelyettesített; Y jelentése oxigén- vagy kénatom, Z jelentése (i) 2,4-dioxo-tiazolidin-5-ilidénil-metilcsoport; (ii) 2,4-dioxo-tiazolidin-5-il-metilcsoport; (iii) 2,4-dioxo-oxazolidin-5-il-metilcsoport; (iv)3,5-dioxo-oxadiazolidin-2-il-metilcsoport; illetve (v) N-hidroxi-ureido-metilcsoport]; R jelentése hidrogén-, halogénatom, alkil-,alkoxi-, hidroxil-, nitro-, adott esetben szubsztituált aminocsoportvagy adott esetben szubsztituált aralkilcsoport; m jelentése 1-5-igbezárólag egész szám. A találmány kiterjed a vegyületeket tartalmazógyógyszerkészítményekre is. Ó
HU0202340A 1999-07-19 2000-07-19 Pharmaceutical compositions containing condensed heterocyclic compounds as active ingredient and their use HUP0202340A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20447699 1999-07-19
PCT/JP2000/004858 WO2001005402A1 (fr) 1999-07-19 2000-07-19 Agents preventifs et therapeutiques du cancer

Publications (2)

Publication Number Publication Date
HUP0202340A2 true HUP0202340A2 (hu) 2003-02-28
HUP0202340A3 HUP0202340A3 (en) 2006-03-28

Family

ID=16491170

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0202340A HUP0202340A3 (en) 1999-07-19 2000-07-19 Pharmaceutical compositions containing condensed heterocyclic compounds as active ingredient and their use

Country Status (18)

Country Link
US (1) US6569877B2 (hu)
EP (1) EP1197211A4 (hu)
KR (1) KR20020015383A (hu)
CN (1) CN1374864A (hu)
AU (1) AU760917B2 (hu)
BR (1) BR0012591A (hu)
CA (1) CA2379662A1 (hu)
CZ (1) CZ2002178A3 (hu)
HU (1) HUP0202340A3 (hu)
IL (1) IL147593A0 (hu)
MX (1) MXPA02000757A (hu)
NO (1) NO20020291L (hu)
NZ (1) NZ516636A (hu)
PL (1) PL352681A1 (hu)
RU (1) RU2219928C2 (hu)
TR (1) TR200200111T2 (hu)
WO (1) WO2001005402A1 (hu)
ZA (1) ZA200200316B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI284533B (en) * 1999-05-24 2007-08-01 Sankyo Co Pharmaceutical composition for treating hyperglycemia, impaired glucose tolerance, diabetes complications and for improving insulin resistant
US9092523B2 (en) 2005-02-28 2015-07-28 Search Engine Technologies, Llc Methods of and systems for searching by incorporating user-entered information
KR101374651B1 (ko) 2005-03-18 2014-03-17 써치 엔진 테크놀로지스, 엘엘씨 서치 결과를 향상시키기 위해 사용자로부터의 피드백을 적용하는 서치 엔진
TW200745099A (en) * 2006-03-02 2007-12-16 Sankyo Co Optically active thiazolidinedione derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3152992B2 (ja) * 1992-04-03 2001-04-03 株式会社興人 過酸化脂質の生成抑制及び消去用組成物
CA2200598C (en) * 1994-09-28 1999-12-07 Shuji Jinno Novel anti-oxidative, tricyclic, condensed heterocyclic compound
JP3820601B2 (ja) * 1995-03-27 2006-09-13 大塚製薬株式会社 活性酸素消去剤
IL118474A (en) * 1995-06-01 2001-08-08 Sankyo Co Benzimideol derivatives and pharmaceutical preparations containing them
US5814647A (en) * 1997-03-04 1998-09-29 Board Of Regents, The University Of Texas System Use of troglitazone and related compounds for the treatment of the climacteric symptoms
TR200000946T2 (tr) * 1997-10-08 2000-07-21 Sankyo Company Limited İkameli füzyonlu heterosiklik bileşimi
AU1507799A (en) * 1997-12-16 1999-07-05 Sankyo Company Limited Leukemia remedy
US6878896B2 (en) * 2002-07-24 2005-04-12 United Parcel Service Of America, Inc. Synchronous semi-automatic parallel sorting

Also Published As

Publication number Publication date
NO20020291D0 (no) 2002-01-18
EP1197211A1 (en) 2002-04-17
NO20020291L (no) 2002-03-18
KR20020015383A (ko) 2002-02-27
BR0012591A (pt) 2002-04-09
MXPA02000757A (es) 2002-07-22
WO2001005402A1 (fr) 2001-01-25
ZA200200316B (en) 2003-06-25
US20020137776A1 (en) 2002-09-26
CZ2002178A3 (cs) 2002-05-15
EP1197211A4 (en) 2004-09-01
IL147593A0 (en) 2002-08-14
TR200200111T2 (tr) 2002-08-21
RU2219928C2 (ru) 2003-12-27
CA2379662A1 (en) 2001-01-25
CN1374864A (zh) 2002-10-16
NZ516636A (en) 2004-01-30
PL352681A1 (en) 2003-09-08
AU760917B2 (en) 2003-05-22
US6569877B2 (en) 2003-05-27
HUP0202340A3 (en) 2006-03-28
AU6021200A (en) 2001-02-05

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees