HUE069799T2 - A PC945 triazol antifungális vegyület polimorfjai - Google Patents
A PC945 triazol antifungális vegyület polimorfjaiInfo
- Publication number
- HUE069799T2 HUE069799T2 HUE20824979A HUE20824979A HUE069799T2 HU E069799 T2 HUE069799 T2 HU E069799T2 HU E20824979 A HUE20824979 A HU E20824979A HU E20824979 A HUE20824979 A HU E20824979A HU E069799 T2 HUE069799 T2 HU E069799T2
- Authority
- HU
- Hungary
- Prior art keywords
- polymorphs
- antifungal compound
- triazole antifungal
- triazole
- compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1917867.2A GB201917867D0 (en) | 2019-12-06 | 2019-12-06 | Polymorphs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE069799T2 true HUE069799T2 (hu) | 2025-04-28 |
Family
ID=69171938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE20824979A HUE069799T2 (hu) | 2019-12-06 | 2020-12-04 | A PC945 triazol antifungális vegyület polimorfjai |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US12491182B2 (enExample) |
| EP (2) | EP4069690B1 (enExample) |
| JP (1) | JP2023505227A (enExample) |
| KR (1) | KR20220110726A (enExample) |
| CN (1) | CN114746415B (enExample) |
| AU (1) | AU2020397613A1 (enExample) |
| BR (1) | BR112022006259A2 (enExample) |
| CA (1) | CA3155829A1 (enExample) |
| CL (1) | CL2022001464A1 (enExample) |
| CO (1) | CO2022007808A2 (enExample) |
| DK (1) | DK4069690T3 (enExample) |
| ES (1) | ES3000984T3 (enExample) |
| FI (1) | FI4069690T3 (enExample) |
| GB (1) | GB201917867D0 (enExample) |
| HR (1) | HRP20250042T1 (enExample) |
| HU (1) | HUE069799T2 (enExample) |
| IL (1) | IL293401A (enExample) |
| LT (1) | LT4069690T (enExample) |
| MX (1) | MX2022006654A (enExample) |
| PL (1) | PL4069690T3 (enExample) |
| PT (1) | PT4069690T (enExample) |
| RS (1) | RS66401B1 (enExample) |
| SA (1) | SA522432879B1 (enExample) |
| SI (1) | SI4069690T1 (enExample) |
| SM (1) | SMT202400514T1 (enExample) |
| WO (1) | WO2021111142A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6669751B2 (ja) | 2014-12-05 | 2020-03-18 | プルモシデ リミテド | 抗真菌化合物 |
| CN117510488B (zh) * | 2022-07-28 | 2025-12-05 | 博瑞制药(苏州)有限公司 | 一种硫酸艾沙康唑的制备方法 |
| CN117330660A (zh) * | 2023-09-14 | 2024-01-02 | 广州医科大学附属第一医院(广州呼吸中心) | Uplc-ms/ms联用检测艾沙康唑的方法及应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1292472C (en) | 1985-12-03 | 1991-11-26 | Alfonsus Guilielmus Knaeps | Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl|-1,3-dioxolan-2-yl|methyl|-1h-imidazoles and 1h-1,2,4-triazoles |
| EP0318214B1 (en) | 1987-11-20 | 1994-12-14 | Schering Corporation | Tri- and tetra-substituted-oxetanes and -tetrahydrofurans and intermediates thereof |
| US5039676A (en) | 1990-05-11 | 1991-08-13 | Schering Corporation | Tri- and tetra-substituted-oxetanes and tetrahydrofurans and intermediates thereof |
| HU225062B1 (en) | 1993-12-21 | 2006-05-29 | Schering Corp | Tetrahydrofuran derivatives with antifungal- effect, pharmaceutical compositions containing them and process for their preparation |
| US5714490A (en) | 1993-12-21 | 1998-02-03 | Schering Corporation | Tetrahydrofuran antifungals |
| US5486625A (en) | 1994-07-08 | 1996-01-23 | Schering Corporation | Process for the preparation of chiral intermediates useful for the synthesis of antifungal agents |
| CZ59497A3 (en) | 1995-06-02 | 1997-08-13 | Schering Corp | Tetrahydrofuran derivative and pharmaceutical composition containing thereof |
| EP0957101A1 (en) | 1998-05-14 | 1999-11-17 | Janssen Pharmaceutica N.V. | Water soluble azoles as broad-spectrum antifungals |
| EP1372394A1 (en) | 2001-04-03 | 2004-01-02 | Schering Corporation | Antifungal composition with enhanced bioavailability |
| EP2141159A1 (en) | 2008-07-03 | 2010-01-06 | Sandoz AG | A Crystalline form of posaconazole |
| US9346791B2 (en) | 2011-09-07 | 2016-05-24 | The Johns Hopkins University | Itraconazole analogs and use thereof |
| JP6669751B2 (ja) | 2014-12-05 | 2020-03-18 | プルモシデ リミテド | 抗真菌化合物 |
-
2019
- 2019-12-06 GB GBGB1917867.2A patent/GB201917867D0/en not_active Ceased
-
2020
- 2020-12-04 SI SI202030565T patent/SI4069690T1/sl unknown
- 2020-12-04 MX MX2022006654A patent/MX2022006654A/es unknown
- 2020-12-04 SM SM20240514T patent/SMT202400514T1/it unknown
- 2020-12-04 US US17/782,232 patent/US12491182B2/en active Active
- 2020-12-04 BR BR112022006259A patent/BR112022006259A2/pt unknown
- 2020-12-04 PT PT208249797T patent/PT4069690T/pt unknown
- 2020-12-04 EP EP20824979.7A patent/EP4069690B1/en active Active
- 2020-12-04 CN CN202080082529.6A patent/CN114746415B/zh active Active
- 2020-12-04 LT LTEPPCT/GB2020/053107T patent/LT4069690T/lt unknown
- 2020-12-04 JP JP2022533459A patent/JP2023505227A/ja active Pending
- 2020-12-04 KR KR1020227012753A patent/KR20220110726A/ko active Pending
- 2020-12-04 AU AU2020397613A patent/AU2020397613A1/en active Pending
- 2020-12-04 FI FIEP20824979.7T patent/FI4069690T3/fi active
- 2020-12-04 CA CA3155829A patent/CA3155829A1/en active Pending
- 2020-12-04 ES ES20824979T patent/ES3000984T3/es active Active
- 2020-12-04 IL IL293401A patent/IL293401A/en unknown
- 2020-12-04 PL PL20824979.7T patent/PL4069690T3/pl unknown
- 2020-12-04 DK DK20824979.7T patent/DK4069690T3/da active
- 2020-12-04 RS RS20250045A patent/RS66401B1/sr unknown
- 2020-12-04 WO PCT/GB2020/053107 patent/WO2021111142A1/en not_active Ceased
- 2020-12-04 EP EP24212504.5A patent/EP4509179A3/en active Pending
- 2020-12-04 HU HUE20824979A patent/HUE069799T2/hu unknown
- 2020-12-04 HR HRP20250042TT patent/HRP20250042T1/hr unknown
-
2022
- 2022-06-01 CO CONC2022/0007808A patent/CO2022007808A2/es unknown
- 2022-06-02 CL CL2022001464A patent/CL2022001464A1/es unknown
- 2022-06-05 SA SA522432879A patent/SA522432879B1/ar unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4069690B1 (en) | 2024-11-13 |
| PL4069690T3 (pl) | 2025-03-10 |
| DK4069690T3 (da) | 2025-01-20 |
| ES3000984T3 (es) | 2025-03-04 |
| FI4069690T3 (fi) | 2025-01-21 |
| US20230028714A1 (en) | 2023-01-26 |
| EP4069690A1 (en) | 2022-10-12 |
| CO2022007808A2 (es) | 2022-06-30 |
| MX2022006654A (es) | 2022-09-07 |
| CN114746415A (zh) | 2022-07-12 |
| JP2023505227A (ja) | 2023-02-08 |
| SA522432879B1 (ar) | 2025-01-26 |
| CA3155829A1 (en) | 2021-06-10 |
| CN114746415B (zh) | 2025-04-11 |
| US12491182B2 (en) | 2025-12-09 |
| PT4069690T (pt) | 2024-12-13 |
| CL2022001464A1 (es) | 2023-03-24 |
| SI4069690T1 (sl) | 2025-03-31 |
| LT4069690T (lt) | 2025-01-10 |
| IL293401A (en) | 2022-07-01 |
| BR112022006259A2 (pt) | 2022-06-21 |
| EP4509179A2 (en) | 2025-02-19 |
| GB201917867D0 (en) | 2020-01-22 |
| HRP20250042T1 (hr) | 2025-03-14 |
| AU2020397613A1 (en) | 2022-06-02 |
| KR20220110726A (ko) | 2022-08-09 |
| WO2021111142A1 (en) | 2021-06-10 |
| SMT202400514T1 (it) | 2025-01-14 |
| EP4509179A3 (en) | 2025-02-26 |
| RS66401B1 (sr) | 2025-02-28 |
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