GB201917867D0 - Polymorphs - Google Patents

Polymorphs

Info

Publication number
GB201917867D0
GB201917867D0 GBGB1917867.2A GB201917867A GB201917867D0 GB 201917867 D0 GB201917867 D0 GB 201917867D0 GB 201917867 A GB201917867 A GB 201917867A GB 201917867 D0 GB201917867 D0 GB 201917867D0
Authority
GB
United Kingdom
Prior art keywords
polymorphs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1917867.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pulmocide Ltd
Original Assignee
Pulmocide Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pulmocide Ltd filed Critical Pulmocide Ltd
Priority to GBGB1917867.2A priority Critical patent/GB201917867D0/en
Publication of GB201917867D0 publication Critical patent/GB201917867D0/en
Priority to AU2020397613A priority patent/AU2020397613A1/en
Priority to EP20824979.7A priority patent/EP4069690B1/en
Priority to CA3155829A priority patent/CA3155829A1/en
Priority to CN202080082529.6A priority patent/CN114746415B/zh
Priority to JP2022533459A priority patent/JP2023505227A/ja
Priority to KR1020227012753A priority patent/KR20220110726A/ko
Priority to HUE20824979A priority patent/HUE069799T2/hu
Priority to MX2022006654A priority patent/MX2022006654A/es
Priority to HRP20250042TT priority patent/HRP20250042T1/hr
Priority to SM20240514T priority patent/SMT202400514T1/it
Priority to BR112022006259A priority patent/BR112022006259A2/pt
Priority to PL20824979.7T priority patent/PL4069690T3/pl
Priority to RS20250045A priority patent/RS66401B1/sr
Priority to PCT/GB2020/053107 priority patent/WO2021111142A1/en
Priority to US17/782,232 priority patent/US12491182B2/en
Priority to EP24212504.5A priority patent/EP4509179A3/en
Priority to FIEP20824979.7T priority patent/FI4069690T3/fi
Priority to DK20824979.7T priority patent/DK4069690T3/da
Priority to IL293401A priority patent/IL293401A/en
Priority to ES20824979T priority patent/ES3000984T3/es
Priority to SI202030565T priority patent/SI4069690T1/sl
Priority to LTEPPCT/GB2020/053107T priority patent/LT4069690T/lt
Priority to PT208249797T priority patent/PT4069690T/pt
Priority to CONC2022/0007808A priority patent/CO2022007808A2/es
Priority to CL2022001464A priority patent/CL2022001464A1/es
Priority to SA522432879A priority patent/SA522432879B1/ar
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GBGB1917867.2A 2019-12-06 2019-12-06 Polymorphs Ceased GB201917867D0 (en)

Priority Applications (27)

Application Number Priority Date Filing Date Title
GBGB1917867.2A GB201917867D0 (en) 2019-12-06 2019-12-06 Polymorphs
PT208249797T PT4069690T (pt) 2019-12-06 2020-12-04 Polimorfos do composto antifúngico de triazol pc945
PL20824979.7T PL4069690T3 (pl) 2019-12-06 2020-12-04 Polimorfy triazolowego związku przeciwgrzybiczego pc945
PCT/GB2020/053107 WO2021111142A1 (en) 2019-12-06 2020-12-04 Polymorphs of triazole antifungal compound pc945
CA3155829A CA3155829A1 (en) 2019-12-06 2020-12-04 Polymorphs of triazole antifungal compound pc945
CN202080082529.6A CN114746415B (zh) 2019-12-06 2020-12-04 三唑抗真菌化合物pc945的多晶型物
JP2022533459A JP2023505227A (ja) 2019-12-06 2020-12-04 トリアゾール抗真菌化合物ｐｃ９４５の多形
KR1020227012753A KR20220110726A (ko) 2019-12-06 2020-12-04 트리아졸 항진균 화합물 pc945의 다형체
HUE20824979A HUE069799T2 (hu) 2019-12-06 2020-12-04 A PC945 triazol antifungális vegyület polimorfjai
MX2022006654A MX2022006654A (es) 2019-12-06 2020-12-04 Polimorfos del compuesto antifungico de triazol pc945.
HRP20250042TT HRP20250042T1 (hr) 2019-12-06 2020-12-04 Polimorfi triazolnog antifungalnog spoja pc945
SM20240514T SMT202400514T1 (it) 2019-12-06 2020-12-04 Polimorfi del composto antimicotico di triazolo pc945
BR112022006259A BR112022006259A2 (pt) 2019-12-06 2020-12-04 Polimorfos de composto antifíngico de triazol pc945
AU2020397613A AU2020397613A1 (en) 2019-12-06 2020-12-04 Polymorphs of triazole antifungal compound PC945
RS20250045A RS66401B1 (sr) 2019-12-06 2020-12-04 Polimorfi antifungalnog jedinjenja triazola, pc945
EP20824979.7A EP4069690B1 (en) 2019-12-06 2020-12-04 Polymorphs of triazole antifungal compound pc945
US17/782,232 US12491182B2 (en) 2019-12-06 2020-12-04 Polymorphs of triazole antifungal compound PC945
EP24212504.5A EP4509179A3 (en) 2019-12-06 2020-12-04 Polymorphs
FIEP20824979.7T FI4069690T3 (fi) 2019-12-06 2020-12-04 Triatsolisienilääkeyhdiste pc945:n polymorfeja
DK20824979.7T DK4069690T3 (da) 2019-12-06 2020-12-04 Polymorfer af den svampedræbende triazolforbindelse pc945
IL293401A IL293401A (en) 2019-12-06 2020-12-04 Polymorphs of the antifungal triazole compound pc945
ES20824979T ES3000984T3 (es) 2019-12-06 2020-12-04 Polimorfos del compuesto antifúngico de triazol PC945
SI202030565T SI4069690T1 (sl) 2019-12-06 2020-12-04 Polimorfi triazolske antimikotične spojine pc945
LTEPPCT/GB2020/053107T LT4069690T (lt) 2019-12-06 2020-12-04 Triazolo priešgrybelinio junginio pc945 polimorfai
CONC2022/0007808A CO2022007808A2 (es) 2019-12-06 2022-06-01 Polimorfos del compuesto antifúngico de triazol pc945
CL2022001464A CL2022001464A1 (es) 2019-12-06 2022-06-02 Polimorfos del compuesto antifúngico de triazol pc945
SA522432879A SA522432879B1 (ar) 2019-12-06 2022-06-05 صور متعددة الأشكال من مركب ترايازول مضاد للفطريات pc945

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1917867.2A GB201917867D0 (en) 2019-12-06 2019-12-06 Polymorphs

Publications (1)

Publication Number Publication Date
GB201917867D0 true GB201917867D0 (en) 2020-01-22

Family

ID=69171938

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1917867.2A Ceased GB201917867D0 (en) 2019-12-06 2019-12-06 Polymorphs

Country Status (26)

Country Link
US (1) US12491182B2 (enExample)
EP (2) EP4069690B1 (enExample)
JP (1) JP2023505227A (enExample)
KR (1) KR20220110726A (enExample)
CN (1) CN114746415B (enExample)
AU (1) AU2020397613A1 (enExample)
BR (1) BR112022006259A2 (enExample)
CA (1) CA3155829A1 (enExample)
CL (1) CL2022001464A1 (enExample)
CO (1) CO2022007808A2 (enExample)
DK (1) DK4069690T3 (enExample)
ES (1) ES3000984T3 (enExample)
FI (1) FI4069690T3 (enExample)
GB (1) GB201917867D0 (enExample)
HR (1) HRP20250042T1 (enExample)
HU (1) HUE069799T2 (enExample)
IL (1) IL293401A (enExample)
LT (1) LT4069690T (enExample)
MX (1) MX2022006654A (enExample)
PL (1) PL4069690T3 (enExample)
PT (1) PT4069690T (enExample)
RS (1) RS66401B1 (enExample)
SA (1) SA522432879B1 (enExample)
SI (1) SI4069690T1 (enExample)
SM (1) SMT202400514T1 (enExample)
WO (1) WO2021111142A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2963625C (en) 2014-12-05 2023-08-22 Pulmocide Limited 4-(4-(4-(((3r,5r)-5-((1h-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl)-n-(4-fluorophenyl)benzamide or salts thereof, and use to treat mycoses
CN117510488B (zh) * 2022-07-28 2025-12-05 博瑞制药(苏州)有限公司 一种硫酸艾沙康唑的制备方法
CN117330660A (zh) * 2023-09-14 2024-01-02 广州医科大学附属第一医院（广州呼吸中心） Uplc-ms/ms联用检测艾沙康唑的方法及应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1292472C (en) 1985-12-03 1991-11-26 Alfonsus Guilielmus Knaeps Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl|-1,3-dioxolan-2-yl|methyl|-1h-imidazoles and 1h-1,2,4-triazoles
WO1989004829A1 (en) 1987-11-20 1989-06-01 Schering Corporation Tri- and tetra-substituted-oxetanes and tetrahydrofurans and intermediates thereof
US5039676A (en) 1990-05-11 1991-08-13 Schering Corporation Tri- and tetra-substituted-oxetanes and tetrahydrofurans and intermediates thereof
AU681753B2 (en) 1993-12-21 1997-09-04 Merck Sharp & Dohme Corp. Tetrahydrofuran antifungals
US5714490A (en) 1993-12-21 1998-02-03 Schering Corporation Tetrahydrofuran antifungals
US5486625A (en) 1994-07-08 1996-01-23 Schering Corporation Process for the preparation of chiral intermediates useful for the synthesis of antifungal agents
AU5928096A (en) 1995-06-02 1996-12-18 Schering Corporation Tetrahydrofuran antifungals
EP0957101A1 (en) 1998-05-14 1999-11-17 Janssen Pharmaceutica N.V. Water soluble azoles as broad-spectrum antifungals
EP1372394A1 (en) 2001-04-03 2004-01-02 Schering Corporation Antifungal composition with enhanced bioavailability
EP2141159A1 (en) * 2008-07-03 2010-01-06 Sandoz AG A Crystalline form of posaconazole
WO2013036866A1 (en) 2011-09-07 2013-03-14 The Johns Hopkins University Itraconazole analogs and use thereof
CA2963625C (en) * 2014-12-05 2023-08-22 Pulmocide Limited 4-(4-(4-(((3r,5r)-5-((1h-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl)-n-(4-fluorophenyl)benzamide or salts thereof, and use to treat mycoses

Also Published As

Publication number Publication date
SA522432879B1 (ar) 2025-01-26
WO2021111142A1 (en) 2021-06-10
US12491182B2 (en) 2025-12-09
EP4509179A3 (en) 2025-02-26
HUE069799T2 (hu) 2025-04-28
AU2020397613A1 (en) 2022-06-02
JP2023505227A (ja) 2023-02-08
CN114746415A (zh) 2022-07-12
CL2022001464A1 (es) 2023-03-24
IL293401A (en) 2022-07-01
LT4069690T (lt) 2025-01-10
US20230028714A1 (en) 2023-01-26
BR112022006259A2 (pt) 2022-06-21
SI4069690T1 (sl) 2025-03-31
PT4069690T (pt) 2024-12-13
RS66401B1 (sr) 2025-02-28
KR20220110726A (ko) 2022-08-09
DK4069690T3 (da) 2025-01-20
CO2022007808A2 (es) 2022-06-30
ES3000984T3 (es) 2025-03-04
MX2022006654A (es) 2022-09-07
EP4069690B1 (en) 2024-11-13
SMT202400514T1 (it) 2025-01-14
HRP20250042T1 (hr) 2025-03-14
EP4069690A1 (en) 2022-10-12
PL4069690T3 (pl) 2025-03-10
FI4069690T3 (fi) 2025-01-21
CN114746415B (zh) 2025-04-11
EP4509179A2 (en) 2025-02-19
CA3155829A1 (en) 2021-06-10

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)