HUE062968T2 - Argináz gátlók és eljárás azok alkalmazására - Google Patents

Argináz gátlók és eljárás azok alkalmazására

Info

Publication number
HUE062968T2
HUE062968T2 HUE20709706A HUE20709706A HUE062968T2 HU E062968 T2 HUE062968 T2 HU E062968T2 HU E20709706 A HUE20709706 A HU E20709706A HU E20709706 A HUE20709706 A HU E20709706A HU E062968 T2 HUE062968 T2 HU E062968T2
Authority
HU
Hungary
Prior art keywords
methods
arginase inhibitors
arginase
inhibitors
Prior art date
Application number
HUE20709706A
Other languages
English (en)
Inventor
Scott Nathan Mlynarski
Tyler Grebe
Sameer Kawatkar
Maurice Raymond Verschoyle Finlay
Iain Simpson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HUE062968T2 publication Critical patent/HUE062968T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HUE20709706A 2019-02-08 2020-02-07 Argináz gátlók és eljárás azok alkalmazására HUE062968T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962802765P 2019-02-08 2019-02-08

Publications (1)

Publication Number Publication Date
HUE062968T2 true HUE062968T2 (hu) 2023-12-28

Family

ID=69770954

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE20709706A HUE062968T2 (hu) 2019-02-08 2020-02-07 Argináz gátlók és eljárás azok alkalmazására

Country Status (29)

Country Link
US (1) US20220106335A1 (hu)
EP (1) EP3921033B1 (hu)
JP (1) JP2022521474A (hu)
KR (1) KR20210126044A (hu)
CN (1) CN113395996B (hu)
AU (1) AU2020218651B2 (hu)
BR (1) BR112021015581A2 (hu)
CA (1) CA3127755A1 (hu)
CL (1) CL2021002056A1 (hu)
CO (1) CO2021011039A2 (hu)
CR (1) CR20210463A (hu)
DK (1) DK3921033T3 (hu)
DO (1) DOP2021000166A (hu)
EA (1) EA202192114A1 (hu)
ES (1) ES2960034T3 (hu)
FI (1) FI3921033T3 (hu)
HR (1) HRP20231092T1 (hu)
HU (1) HUE062968T2 (hu)
IL (1) IL285108A (hu)
LT (1) LT3921033T (hu)
MA (1) MA56324B1 (hu)
MX (1) MX2021009499A (hu)
PE (1) PE20220280A1 (hu)
PL (1) PL3921033T3 (hu)
PT (1) PT3921033T (hu)
RS (1) RS64781B1 (hu)
SG (1) SG11202108503PA (hu)
SI (1) SI3921033T1 (hu)
WO (1) WO2020161675A1 (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202228720A (zh) 2020-12-22 2022-08-01 波蘭商昂科艾倫迪治療法股份公司 精胺酸酶抑制劑及其使用方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901572D0 (sv) * 1999-05-03 1999-05-03 Astra Ab New compounds
SE0300907D0 (sv) * 2003-03-31 2003-03-31 Astrazeneca Ab Novel compounds
RS58965B1 (sr) * 2009-01-26 2019-08-30 Univ Pennsylvania Inhibitori arginaze i postupci upotrebe
MY162535A (en) * 2010-04-22 2017-06-15 Mars Inc Inhibitors of arginase and their therapeutic applications
CN103249737B (zh) * 2010-10-26 2016-06-08 马尔斯公司 作为精氨酸酶抑制剂的硼酸盐
BR112014009415B1 (pt) * 2011-10-19 2021-11-23 Mars, Incorporated Composição farmacêutica, composto inbidor de arginase e seus usos
CN104995178B (zh) * 2012-12-17 2018-06-26 帕里昂科学公司 3,5-二氨基-6-氯-n-(n-(4-苯基丁基)甲脒基)吡嗪-2-甲酰胺化合物
PL410665A1 (pl) * 2014-12-29 2016-07-04 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Inhibitory arginazy oraz ich zastosowania terapeutyczne
WO2017175185A1 (en) * 2016-04-08 2017-10-12 Novartis Ag Heteroaryl butanoic acid derivatives as lta4h inhibitors
TWI818902B (zh) * 2016-12-22 2023-10-21 美商卡利泰拉生物科技公司 用於抑制精胺酸酶活性的組合物及方法
CN108794517B (zh) * 2017-04-27 2021-03-30 南京谷睿生物科技有限公司 一种精氨酸酶抑制剂及其制备方法与用途
CN111770756B (zh) * 2018-04-27 2023-03-31 四川科伦博泰生物医药股份有限公司 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途

Also Published As

Publication number Publication date
SG11202108503PA (en) 2021-09-29
CR20210463A (es) 2021-10-15
LT3921033T (lt) 2023-09-25
CA3127755A1 (en) 2020-08-13
CN113395996A (zh) 2021-09-14
MA56324B1 (fr) 2023-10-31
IL285108A (en) 2021-09-30
EP3921033B1 (en) 2023-07-26
ES2960034T3 (es) 2024-02-29
PE20220280A1 (es) 2022-02-25
RS64781B1 (sr) 2023-11-30
BR112021015581A2 (pt) 2021-10-05
JP2022521474A (ja) 2022-04-08
DK3921033T3 (da) 2023-10-16
EP3921033A1 (en) 2021-12-15
AU2020218651A1 (en) 2021-09-30
KR20210126044A (ko) 2021-10-19
DOP2021000166A (es) 2021-09-30
PL3921033T3 (pl) 2024-01-15
US20220106335A1 (en) 2022-04-07
PT3921033T (pt) 2023-10-11
CN113395996B (zh) 2024-05-28
AU2020218651B2 (en) 2023-01-12
SI3921033T1 (sl) 2023-11-30
WO2020161675A1 (en) 2020-08-13
FI3921033T3 (fi) 2023-09-15
EA202192114A1 (ru) 2021-12-01
HRP20231092T1 (hr) 2023-12-22
CO2021011039A2 (es) 2021-09-09
MX2021009499A (es) 2021-09-08
CL2021002056A1 (es) 2022-03-04

Similar Documents

Publication Publication Date Title
IL287940A (en) fgfr inhibitors and methods of using them
IL276711A (en) Arginase inhibitors and methods of using them
IL287751A (en) kcnt1 inhibitors and methods of use
IL287768A (en) kcnt1 inhibitors and methods of use
IL279475A (en) Actonucleotidase inhibitors and methods of using them
EP3765006A4 (en) ARGINASE INHIBITORS AND METHODS OF USE
IL283592A (en) Apol1 inhibitors and methods of using them
IL284640A (en) PCSK9 inhibitors and methods of using them
IL287973A (en) acss2 inhibitors and methods of their use
IL284661A (en) pcsk9 inhibitors and methods of using them
EP3810615A4 (en) ARGINASE INHIBITORS AND METHODS OF USE
EP3897622A4 (en) ARGINASE INHIBITORS AND METHODS OF USE
EP3986894A4 (en) ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF
IL280924A (en) Arginase inhibitors and methods of using them
IL292860A (en) Allosteric egfr inhibitors and methods of using them
EP3846808A4 (en) PAPD5 INHIBITORS AND METHODS OF USE THEREOF
IL289649A (en) Formulations of rbp4 inhibitors and methods of use
EP3959197A4 (en) PAPD5 INHIBITORS AND METHODS OF USE THEREOF
IL264854A (en) Spt5 inhibitors and methods of use thereof
EP4087583A4 (en) ARGINASE INHIBITORS AND METHODS OF USE
IL285108A (en) Arginase inhibitors and methods of using them
EP4077332A4 (en) LIN28 INHIBITORS AND THEIR METHODS OF USE
EP3968994C0 (en) ABHD12 INHIBITORS AND METHODS FOR THE PRODUCTION AND USE THEREOF