DK3921033T3 - Arginasehæmmere og fremgangsmåder til anvendelse deraf - Google Patents

Arginasehæmmere og fremgangsmåder til anvendelse deraf Download PDF

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Publication number
DK3921033T3
DK3921033T3 DK20709706.4T DK20709706T DK3921033T3 DK 3921033 T3 DK3921033 T3 DK 3921033T3 DK 20709706 T DK20709706 T DK 20709706T DK 3921033 T3 DK3921033 T3 DK 3921033T3
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DK
Denmark
Prior art keywords
methods
arginase inhibitors
arginase
inhibitors
Prior art date
Application number
DK20709706.4T
Other languages
English (en)
Inventor
Scott Nathan Mlynarski
Tyler Grebe
Sameer Kawatkar
Maurice Raymond Verschoyle Finlay
Iain Simpson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK3921033T3 publication Critical patent/DK3921033T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK20709706.4T 2019-02-08 2020-02-07 Arginasehæmmere og fremgangsmåder til anvendelse deraf DK3921033T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962802765P 2019-02-08 2019-02-08
PCT/IB2020/050982 WO2020161675A1 (en) 2019-02-08 2020-02-07 Arginase inhibitors and methods of use thereof

Publications (1)

Publication Number Publication Date
DK3921033T3 true DK3921033T3 (da) 2023-10-16

Family

ID=69770954

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20709706.4T DK3921033T3 (da) 2019-02-08 2020-02-07 Arginasehæmmere og fremgangsmåder til anvendelse deraf

Country Status (29)

Country Link
US (1) US20220106335A1 (da)
EP (1) EP3921033B1 (da)
JP (1) JP2022521474A (da)
KR (1) KR20210126044A (da)
CN (1) CN113395996B (da)
AU (1) AU2020218651B2 (da)
BR (1) BR112021015581A2 (da)
CA (1) CA3127755A1 (da)
CL (1) CL2021002056A1 (da)
CO (1) CO2021011039A2 (da)
CR (1) CR20210463A (da)
DK (1) DK3921033T3 (da)
DO (1) DOP2021000166A (da)
EA (1) EA202192114A1 (da)
ES (1) ES2960034T3 (da)
FI (1) FI3921033T3 (da)
HR (1) HRP20231092T1 (da)
HU (1) HUE062968T2 (da)
IL (1) IL285108A (da)
LT (1) LT3921033T (da)
MA (1) MA56324B1 (da)
MX (1) MX2021009499A (da)
PE (1) PE20220280A1 (da)
PL (1) PL3921033T3 (da)
PT (1) PT3921033T (da)
RS (1) RS64781B1 (da)
SG (1) SG11202108503PA (da)
SI (1) SI3921033T1 (da)
WO (1) WO2020161675A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202228720A (zh) 2020-12-22 2022-08-01 波蘭商昂科艾倫迪治療法股份公司 精胺酸酶抑制劑及其使用方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901572D0 (sv) * 1999-05-03 1999-05-03 Astra Ab New compounds
SE0300907D0 (sv) * 2003-03-31 2003-03-31 Astrazeneca Ab Novel compounds
EP2389352B1 (en) * 2009-01-26 2019-05-08 The Trustees Of The University Of Pennsylvania Arginase inhibitors and methods of use
NZ603364A (en) * 2010-04-22 2015-06-26 Mars Inc Inhibitors of arginase and their therapeutic applications
DK2632927T3 (da) * 2010-10-26 2016-04-11 Mars Inc Boronater som arginsaseinhibitorer
WO2013059437A1 (en) * 2011-10-19 2013-04-25 Mars, Incorporated Inhibitors of arginase and their therapeutic applications
BR112015014178A2 (pt) * 2012-12-17 2017-07-11 Parion Sciences Inc compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida
PL410665A1 (pl) * 2014-12-29 2016-07-04 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Inhibitory arginazy oraz ich zastosowania terapeutyczne
WO2017175185A1 (en) * 2016-04-08 2017-10-12 Novartis Ag Heteroaryl butanoic acid derivatives as lta4h inhibitors
KR102579849B1 (ko) * 2016-12-22 2023-09-18 칼리테라 바이오사이언시즈, 인코포레이티드 아르기나제 활성을 억제시키기 위한 조성물 및 방법
CN108794517B (zh) * 2017-04-27 2021-03-30 南京谷睿生物科技有限公司 一种精氨酸酶抑制剂及其制备方法与用途
WO2019205979A1 (zh) * 2018-04-27 2019-10-31 四川科伦博泰生物医药股份有限公司 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途

Also Published As

Publication number Publication date
CN113395996A (zh) 2021-09-14
LT3921033T (lt) 2023-09-25
RS64781B1 (sr) 2023-11-30
BR112021015581A2 (pt) 2021-10-05
CO2021011039A2 (es) 2021-09-09
JP2022521474A (ja) 2022-04-08
HUE062968T2 (hu) 2023-12-28
EA202192114A1 (ru) 2021-12-01
FI3921033T3 (fi) 2023-09-15
SG11202108503PA (en) 2021-09-29
PE20220280A1 (es) 2022-02-25
MX2021009499A (es) 2021-09-08
EP3921033B1 (en) 2023-07-26
WO2020161675A1 (en) 2020-08-13
CR20210463A (es) 2021-10-15
US20220106335A1 (en) 2022-04-07
IL285108A (en) 2021-09-30
CA3127755A1 (en) 2020-08-13
SI3921033T1 (sl) 2023-11-30
PL3921033T3 (pl) 2024-01-15
MA56324B1 (fr) 2023-10-31
AU2020218651A1 (en) 2021-09-30
AU2020218651B2 (en) 2023-01-12
CL2021002056A1 (es) 2022-03-04
ES2960034T3 (es) 2024-02-29
HRP20231092T1 (hr) 2023-12-22
EP3921033A1 (en) 2021-12-15
KR20210126044A (ko) 2021-10-19
PT3921033T (pt) 2023-10-11
DOP2021000166A (es) 2021-09-30
CN113395996B (zh) 2024-05-28

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