HUE062202T2 - Nyújtott hatóanyagleadású fájdalomcsillapító készítmények, és eljárás azok elõállítására - Google Patents

Nyújtott hatóanyagleadású fájdalomcsillapító készítmények, és eljárás azok elõállítására

Info

Publication number
HUE062202T2
HUE062202T2 HUE18773692A HUE18773692A HUE062202T2 HU E062202 T2 HUE062202 T2 HU E062202T2 HU E18773692 A HUE18773692 A HU E18773692A HU E18773692 A HUE18773692 A HU E18773692A HU E062202 T2 HUE062202 T2 HU E062202T2
Authority
HU
Hungary
Prior art keywords
sustained
preparation
methods
anesthetic compositions
release anesthetic
Prior art date
Application number
HUE18773692A
Other languages
English (en)
Inventor
Keelung Hong
Hao-Wen Kao
Yi-Yu Lin
Luke Guo
Original Assignee
Tlc Biopharmaceuticals Inc
Taiwan Liposome Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tlc Biopharmaceuticals Inc, Taiwan Liposome Co Ltd filed Critical Tlc Biopharmaceuticals Inc
Publication of HUE062202T2 publication Critical patent/HUE062202T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HUE18773692A 2017-08-28 2018-08-28 Nyújtott hatóanyagleadású fájdalomcsillapító készítmények, és eljárás azok elõállítására HUE062202T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762550983P 2017-08-28 2017-08-28
US201862621730P 2018-01-25 2018-01-25

Publications (1)

Publication Number Publication Date
HUE062202T2 true HUE062202T2 (hu) 2023-10-28

Family

ID=63668016

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE18773692A HUE062202T2 (hu) 2017-08-28 2018-08-28 Nyújtott hatóanyagleadású fájdalomcsillapító készítmények, és eljárás azok elõállítására

Country Status (22)

Country Link
US (2) US11793799B2 (hu)
EP (1) EP3675816B1 (hu)
JP (1) JP7173615B2 (hu)
KR (1) KR20200044902A (hu)
CN (1) CN111182889A (hu)
AU (2) AU2018323436B2 (hu)
BR (1) BR112020003743A2 (hu)
CA (1) CA3073734A1 (hu)
CY (1) CY1126137T1 (hu)
DK (1) DK3675816T3 (hu)
ES (1) ES2946919T3 (hu)
FI (1) FI3675816T3 (hu)
HR (1) HRP20230535T1 (hu)
HU (1) HUE062202T2 (hu)
LT (1) LT3675816T (hu)
MX (1) MX2020002231A (hu)
PL (1) PL3675816T3 (hu)
PT (1) PT3675816T (hu)
RS (1) RS64297B1 (hu)
SI (1) SI3675816T1 (hu)
TW (1) TWI806894B (hu)
WO (1) WO2019046293A1 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019245447A1 (en) 2018-03-30 2020-10-22 Tlc Biopharmaceuticals, Inc. Sustained-release anesthetic compositions and methods of preparation thereof
US20220071934A1 (en) * 2019-02-26 2022-03-10 Taiwan Liposome Company, Ltd. Pharmaceutical compositions for use in treating pain
EP3991722A4 (en) * 2019-06-28 2022-10-05 Jiangsu Hengrui Medicine Co., Ltd. LIPID COMPOSITION WITH DELAYED RELEASE AND THEIR PROCESS OF PRODUCTION
CN113116823B (zh) * 2019-12-30 2024-02-20 江苏恒瑞医药股份有限公司 一种脂质体及其制备方法
CN114980893B (zh) 2020-01-14 2023-12-29 中国科学院上海药物研究所 一种长效罗哌卡因药物组合物及其制备方法和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2592791A1 (fr) * 1986-01-14 1987-07-17 Ire Celltarg Sa Composition pharmaceutique, contenant un anesthesique local et/ou un analgesique central encapsule dans des liposomes
US5244678A (en) 1986-01-14 1993-09-14 Ire-Celltarg S.A. Pharmaceutical composition containing a local anesthetic and/or centrally acting analgesic encapsulated in liposomes
US5227165A (en) * 1989-11-13 1993-07-13 Nova Pharmaceutical Corporation Liposphere delivery systems for local anesthetics
GB9605915D0 (en) 1996-03-21 1996-05-22 Univ Bruxelles Liposome encapsulated amphiphilic drug compositions
GB9609779D0 (en) 1996-05-10 1996-07-17 Univ Bruxelles Freeze dried liposome encapsulated amphiphilic drug compositions and a process for the preparation thereof
ATE535232T1 (de) 1997-09-18 2011-12-15 Pacira Pharmaceuticals Inc Retardierte freisetzung liposomaler anesthetischer zusammensetzungen
IL138672A0 (en) 1998-03-31 2001-10-31 Yissum Res Dev Co Liposomal bupivacaine compositions and methods of preparation
ATE355827T1 (de) 1998-08-12 2007-03-15 Yissum Res Dev Co Mittels ammoniumsulfatgradient hergestellte liposomale therapeutische zusammensetzungen
CN102940878A (zh) * 2006-10-06 2013-02-27 Scil技术股份有限公司 脊柱髓核植入物
WO2013146386A1 (ja) * 2012-03-27 2013-10-03 学校法人関西医科大学 局所麻酔薬持続性徐放製剤
TW201427447A (zh) 2012-09-17 2014-07-01 Interdigital Patent Holdings 回載無線電資源及小胞元回載延遲估計自我最佳化
JPWO2014046191A1 (ja) * 2012-09-21 2016-08-18 テルモ株式会社 局所麻酔薬持続徐放性リポソーム製剤
CN103142458B (zh) * 2013-01-22 2015-09-09 莱普德制药有限公司 无成瘾性镇痛缓释递药系统的组方与制备方法
WO2018048460A1 (en) 2014-04-21 2018-03-15 Heron Therapeutics, Inc. A pharmaceutical composition comprising a delivery system, an amide-type local anesthetic, and meloxicam

Also Published As

Publication number Publication date
BR112020003743A2 (pt) 2020-09-01
EP3675816A1 (en) 2020-07-08
MX2020002231A (es) 2022-06-14
US20240000764A1 (en) 2024-01-04
PL3675816T3 (pl) 2023-09-25
PT3675816T (pt) 2023-05-31
LT3675816T (lt) 2023-06-26
AU2018323436A1 (en) 2020-03-12
JP2020531540A (ja) 2020-11-05
CY1126137T1 (el) 2023-11-15
TW201919598A (zh) 2019-06-01
JP7173615B2 (ja) 2022-11-16
RS64297B1 (sr) 2023-07-31
CA3073734A1 (en) 2019-03-07
CN111182889A (zh) 2020-05-19
SI3675816T1 (sl) 2023-10-30
EP3675816B1 (en) 2023-05-17
AU2023266253A1 (en) 2023-12-07
US20200188374A1 (en) 2020-06-18
AU2018323436B2 (en) 2023-12-21
FI3675816T3 (fi) 2023-06-02
RU2020112204A3 (hu) 2022-02-28
KR20200044902A (ko) 2020-04-29
WO2019046293A1 (en) 2019-03-07
DK3675816T3 (da) 2023-05-30
TWI806894B (zh) 2023-07-01
ES2946919T3 (es) 2023-07-27
HRP20230535T1 (hr) 2023-09-15
RU2020112204A (ru) 2021-10-04
US11793799B2 (en) 2023-10-24

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