DK3675816T3 - Anæstetiske sammensætninger med vedvarende frigivelse og fremgangsmåder til fremstilling deraf - Google Patents

Anæstetiske sammensætninger med vedvarende frigivelse og fremgangsmåder til fremstilling deraf Download PDF

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Publication number
DK3675816T3
DK3675816T3 DK18773692.1T DK18773692T DK3675816T3 DK 3675816 T3 DK3675816 T3 DK 3675816T3 DK 18773692 T DK18773692 T DK 18773692T DK 3675816 T3 DK3675816 T3 DK 3675816T3
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DK
Denmark
Prior art keywords
preparation
methods
sustained release
anesthetic compositions
anesthetic
Prior art date
Application number
DK18773692.1T
Other languages
English (en)
Inventor
Hao-Wen Kao
Yi-Yu Lin
Keelung Hong
Luke S S Guo
Original Assignee
Tlc Biopharmaceuticals Inc
Taiwan Liposome Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tlc Biopharmaceuticals Inc, Taiwan Liposome Co Ltd filed Critical Tlc Biopharmaceuticals Inc
Application granted granted Critical
Publication of DK3675816T3 publication Critical patent/DK3675816T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
DK18773692.1T 2017-08-28 2018-08-28 Anæstetiske sammensætninger med vedvarende frigivelse og fremgangsmåder til fremstilling deraf DK3675816T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762550983P 2017-08-28 2017-08-28
US201862621730P 2018-01-25 2018-01-25
PCT/US2018/048329 WO2019046293A1 (en) 2017-08-28 2018-08-28 EXTENDED RELEASE ANESTHETIC COMPOSITIONS AND METHODS OF PREPARATION THEREOF

Publications (1)

Publication Number Publication Date
DK3675816T3 true DK3675816T3 (da) 2023-05-30

Family

ID=63668016

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18773692.1T DK3675816T3 (da) 2017-08-28 2018-08-28 Anæstetiske sammensætninger med vedvarende frigivelse og fremgangsmåder til fremstilling deraf

Country Status (22)

Country Link
US (2) US11793799B2 (da)
EP (1) EP3675816B1 (da)
JP (1) JP7173615B2 (da)
KR (1) KR20200044902A (da)
CN (1) CN111182889A (da)
AU (2) AU2018323436B2 (da)
BR (1) BR112020003743A2 (da)
CA (1) CA3073734A1 (da)
CY (1) CY1126137T1 (da)
DK (1) DK3675816T3 (da)
ES (1) ES2946919T3 (da)
FI (1) FI3675816T3 (da)
HR (1) HRP20230535T1 (da)
HU (1) HUE062202T2 (da)
LT (1) LT3675816T (da)
MX (1) MX2020002231A (da)
PL (1) PL3675816T3 (da)
PT (1) PT3675816T (da)
RS (1) RS64297B1 (da)
SI (1) SI3675816T1 (da)
TW (1) TWI806894B (da)
WO (1) WO2019046293A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020010290A (es) * 2018-03-30 2020-10-28 Tlc Biopharmaceuticals Inc Composiciones anestesicas de liberacion sostenida y metodos de preparacion de las mismas.
CN113473972A (zh) * 2019-02-26 2021-10-01 美商Tlc生物医药公司 用于治疗疼痛的药学组成物
EP3991722A4 (en) * 2019-06-28 2022-10-05 Jiangsu Hengrui Medicine Co., Ltd. LIPID COMPOSITION WITH DELAYED RELEASE AND THEIR PROCESS OF PRODUCTION
CN113116823B (zh) * 2019-12-30 2024-02-20 江苏恒瑞医药股份有限公司 一种脂质体及其制备方法
EP4091612A4 (en) 2020-01-14 2024-01-24 Shanghai Inst Materia Medica Cas PHARMACEUTICAL COMPOSITION OF LONG-ACTING ROPIVACAINE, PREPARATION METHOD AND USE THEREOF

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244678A (en) 1986-01-14 1993-09-14 Ire-Celltarg S.A. Pharmaceutical composition containing a local anesthetic and/or centrally acting analgesic encapsulated in liposomes
FR2592791A1 (fr) * 1986-01-14 1987-07-17 Ire Celltarg Sa Composition pharmaceutique, contenant un anesthesique local et/ou un analgesique central encapsule dans des liposomes
US5227165A (en) * 1989-11-13 1993-07-13 Nova Pharmaceutical Corporation Liposphere delivery systems for local anesthetics
GB9605915D0 (en) 1996-03-21 1996-05-22 Univ Bruxelles Liposome encapsulated amphiphilic drug compositions
GB9609779D0 (en) 1996-05-10 1996-07-17 Univ Bruxelles Freeze dried liposome encapsulated amphiphilic drug compositions and a process for the preparation thereof
DE69841598D1 (de) * 1997-09-18 2010-05-20 Pacira Pharmaceuticals Inc Retardierte freisetzung liposmaler anesthetischer zusammensetzungen.
CA2326348C (en) * 1998-03-31 2009-10-06 Yissum Research Development Company Of The Hebrew University In Jerusalem Liposomal bupivacaine compositions and methods of preparation
CA2340118C (en) 1998-08-12 2009-01-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Liposomal bupivacaine compositions prepared using an ammonium sulfate gradient
TWI455731B (zh) * 2006-10-06 2014-10-11 Scil Technology Gmbh 醫藥應用的乾燥重建之囊胞結構
WO2013146386A1 (ja) * 2012-03-27 2013-10-03 学校法人関西医科大学 局所麻酔薬持続性徐放製剤
TW201427447A (zh) 2012-09-17 2014-07-01 Interdigital Patent Holdings 回載無線電資源及小胞元回載延遲估計自我最佳化
WO2014046191A1 (ja) * 2012-09-21 2014-03-27 テルモ株式会社 局所麻酔薬持続徐放性リポソーム製剤
CN103142458B (zh) * 2013-01-22 2015-09-09 莱普德制药有限公司 无成瘾性镇痛缓释递药系统的组方与制备方法
US11083730B2 (en) 2014-04-21 2021-08-10 Heron Therapeutics, Inc. Long-acting polymeric delivery systems

Also Published As

Publication number Publication date
AU2018323436B2 (en) 2023-12-21
US20240000764A1 (en) 2024-01-04
AU2018323436A1 (en) 2020-03-12
AU2023266253A1 (en) 2023-12-07
CN111182889A (zh) 2020-05-19
RU2020112204A (ru) 2021-10-04
KR20200044902A (ko) 2020-04-29
HRP20230535T1 (hr) 2023-09-15
ES2946919T3 (es) 2023-07-27
RS64297B1 (sr) 2023-07-31
CA3073734A1 (en) 2019-03-07
TWI806894B (zh) 2023-07-01
JP2020531540A (ja) 2020-11-05
RU2020112204A3 (da) 2022-02-28
TW201919598A (zh) 2019-06-01
SI3675816T1 (sl) 2023-10-30
EP3675816B1 (en) 2023-05-17
FI3675816T3 (fi) 2023-06-02
BR112020003743A2 (pt) 2020-09-01
LT3675816T (lt) 2023-06-26
PL3675816T3 (pl) 2023-09-25
US20200188374A1 (en) 2020-06-18
EP3675816A1 (en) 2020-07-08
WO2019046293A1 (en) 2019-03-07
PT3675816T (pt) 2023-05-31
JP7173615B2 (ja) 2022-11-16
CY1126137T1 (el) 2023-11-15
HUE062202T2 (hu) 2023-10-28
MX2020002231A (es) 2022-06-14
US11793799B2 (en) 2023-10-24

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