DK2968479T3 - Terapeutiske sure ceramidasesammensætninger og fremgangsmåder til fremstilling og anvendelse heraf - Google Patents

Terapeutiske sure ceramidasesammensætninger og fremgangsmåder til fremstilling og anvendelse heraf Download PDF

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DK2968479T3
DK2968479T3 DK14775400.6T DK14775400T DK2968479T3 DK 2968479 T3 DK2968479 T3 DK 2968479T3 DK 14775400 T DK14775400 T DK 14775400T DK 2968479 T3 DK2968479 T3 DK 2968479T3
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sure
therapeutic
preparing
methods
ceramidase
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DK14775400.6T
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Edward H Schuchman
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Icahn School Med Mount Sinai
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01023—Ceramidase (3.5.1.23)

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  • General Health & Medical Sciences (AREA)
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  • Cardiology (AREA)
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  • Immunology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Biotechnology (AREA)
DK14775400.6T 2013-03-14 2014-03-13 Terapeutiske sure ceramidasesammensætninger og fremgangsmåder til fremstilling og anvendelse heraf DK2968479T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361784594P 2013-03-14 2013-03-14
PCT/US2014/026481 WO2014160390A1 (en) 2013-03-14 2014-03-13 Therapeutic acid ceramidase compositions and methods of making and using them

Publications (1)

Publication Number Publication Date
DK2968479T3 true DK2968479T3 (da) 2019-08-12

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DK14775400.6T DK2968479T3 (da) 2013-03-14 2014-03-13 Terapeutiske sure ceramidasesammensætninger og fremgangsmåder til fremstilling og anvendelse heraf

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Country Link
US (3) US9937246B2 (da)
EP (2) EP2968479B1 (da)
JP (4) JP6832158B2 (da)
CA (1) CA2905449A1 (da)
DK (1) DK2968479T3 (da)
ES (1) ES2739811T3 (da)
HK (1) HK1220399A1 (da)
HR (1) HRP20191361T1 (da)
HU (1) HUE046113T2 (da)
IL (4) IL241390B (da)
MX (2) MX2015012471A (da)
PL (1) PL2968479T3 (da)
PT (1) PT2968479T (da)
WO (1) WO2014160390A1 (da)

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ES2791760T3 (es) 2011-09-07 2020-11-05 Sinai School Medicine Ceramidasa y diferenciación celular
LT2854910T (lt) 2012-06-01 2020-05-25 Icahn School Of Medicine At Mount Sinai Ceramido lygiai infekcijos gydymo ir prevencijos metu
PT2968479T (pt) * 2013-03-14 2019-08-07 Icahn School Med Mount Sinai Composições terapêuticas de ceramidase ácida e métodos de fabrico e utilização
AU2018207564A1 (en) * 2017-01-13 2019-08-08 Icahn School Of Medicine At Mount Sinai Compositions and methods for treating farber disease
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US20180193436A1 (en) 2018-07-12
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EP2968479A4 (en) 2016-07-27
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JP2016520519A (ja) 2016-07-14
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IL288427A (en) 2022-01-01
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JP2021042227A (ja) 2021-03-18
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JP6832386B2 (ja) 2021-02-24
HRP20191361T1 (hr) 2019-11-01
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