PT2854910T - Níveis de ceramida no tratamento e prevenção de infeções - Google Patents

Níveis de ceramida no tratamento e prevenção de infeções

Info

Publication number
PT2854910T
PT2854910T PT137976353T PT13797635T PT2854910T PT 2854910 T PT2854910 T PT 2854910T PT 137976353 T PT137976353 T PT 137976353T PT 13797635 T PT13797635 T PT 13797635T PT 2854910 T PT2854910 T PT 2854910T
Authority
PT
Portugal
Prior art keywords
infections
prevention
treatment
ceramide levels
ceramide
Prior art date
Application number
PT137976353T
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Icahn School Med Mount Sinai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev, Icahn School Med Mount Sinai filed Critical Yeda Res & Dev
Publication of PT2854910T publication Critical patent/PT2854910T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01023—Ceramidase (3.5.1.23)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Otolaryngology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT137976353T 2012-06-01 2013-05-31 Níveis de ceramida no tratamento e prevenção de infeções PT2854910T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261654519P 2012-06-01 2012-06-01

Publications (1)

Publication Number Publication Date
PT2854910T true PT2854910T (pt) 2020-05-06

Family

ID=49673925

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137976353T PT2854910T (pt) 2012-06-01 2013-05-31 Níveis de ceramida no tratamento e prevenção de infeções

Country Status (14)

Country Link
US (4) US9492514B2 (pt)
EP (2) EP3679923B1 (pt)
JP (4) JP6369814B2 (pt)
CN (2) CN104582770B (pt)
CA (1) CA2874146C (pt)
DK (1) DK2854910T3 (pt)
ES (2) ES2897825T3 (pt)
HR (1) HRP20200661T1 (pt)
HU (1) HUE051020T2 (pt)
LT (1) LT2854910T (pt)
PL (1) PL2854910T3 (pt)
PT (1) PT2854910T (pt)
SI (1) SI2854910T1 (pt)
WO (1) WO2013181530A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006007560A2 (en) 2004-07-01 2006-01-19 University Of Pennsylvania Targeted protein replacement for the treatment of lysosomal storage disorders
DK3219705T3 (da) 2005-12-28 2020-04-14 Vertex Pharma Farmaceutiske sammensætninger af den amorfe form af n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinolin-3-carboxamid
EP3741384A1 (en) 2011-09-07 2020-11-25 Mount Sinai School Of Medicine Ceramidase and cell differentiation
WO2013181530A1 (en) * 2012-06-01 2013-12-05 Icahn School Of Medicine At Mount Sinai Ceramide levels in the treatment and prevention of infections
WO2014138999A1 (en) 2013-03-14 2014-09-18 University Of Ottawa Methods for the diagnosis and treatment of inflammatory bowel disease
PL2968479T3 (pl) 2013-03-14 2019-10-31 Icahn School Med Mount Sinai Kompozycje terapeutyczne ceramidazy kwasowej i sposoby ich wytwarzania i stosowania
CA2962802A1 (en) 2014-10-03 2016-04-07 University Of Ottawa Markers for inflammatory bowel disease
JP6746569B2 (ja) 2014-10-07 2020-08-26 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ 嚢胞性線維症膜貫通コンダクタンス制御因子のモジュレーターの共結晶
AU2018207564A1 (en) * 2017-01-13 2019-08-08 Icahn School Of Medicine At Mount Sinai Compositions and methods for treating farber disease
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Also Published As

Publication number Publication date
JP2015518054A (ja) 2015-06-25
CA2874146A1 (en) 2013-12-05
CN104582770A (zh) 2015-04-29
ES2897825T3 (es) 2022-03-02
EP3679923B1 (en) 2021-08-04
US9492514B2 (en) 2016-11-15
JP2018162303A (ja) 2018-10-18
US20150125439A1 (en) 2015-05-07
CN109529028A (zh) 2019-03-29
JP6639574B2 (ja) 2020-02-05
US20170020998A1 (en) 2017-01-26
JP2020050668A (ja) 2020-04-02
CA2874146C (en) 2023-03-21
ES2786128T3 (es) 2020-10-08
DK2854910T3 (da) 2020-05-04
LT2854910T (lt) 2020-05-25
SI2854910T1 (sl) 2020-09-30
CN104582770B (zh) 2019-01-29
US20220202919A1 (en) 2022-06-30
EP2854910B1 (en) 2020-04-15
US10159724B2 (en) 2018-12-25
EP2854910A1 (en) 2015-04-08
EP2854910A4 (en) 2016-02-24
EP3679923A1 (en) 2020-07-15
HUE051020T2 (hu) 2021-01-28
PL2854910T3 (pl) 2020-07-27
US20190151424A1 (en) 2019-05-23
HRP20200661T1 (hr) 2020-10-30
JP2023021305A (ja) 2023-02-10
WO2013181530A1 (en) 2013-12-05
JP6369814B2 (ja) 2018-08-08

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