HUE062089T2 - Antitest, amely tartalmaz glutamintartalmú könnyû lánc C-terminális meghosszabbítást, annak konjugátumai, és eljárások és felhasználások - Google Patents
Antitest, amely tartalmaz glutamintartalmú könnyû lánc C-terminális meghosszabbítást, annak konjugátumai, és eljárások és felhasználásokInfo
- Publication number
- HUE062089T2 HUE062089T2 HUE19821395A HUE19821395A HUE062089T2 HU E062089 T2 HUE062089 T2 HU E062089T2 HU E19821395 A HUE19821395 A HU E19821395A HU E19821395 A HUE19821395 A HU E19821395A HU E062089 T2 HUE062089 T2 HU E062089T2
- Authority
- HU
- Hungary
- Prior art keywords
- conjugates
- glutamine
- antibody
- methods
- light chain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862773708P | 2018-11-30 | 2018-11-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE062089T2 true HUE062089T2 (hu) | 2023-09-28 |
Family
ID=68916605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE19821395A HUE062089T2 (hu) | 2018-11-30 | 2019-11-25 | Antitest, amely tartalmaz glutamintartalmú könnyû lánc C-terminális meghosszabbítást, annak konjugátumai, és eljárások és felhasználások |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20220016260A1 (hu) |
| EP (1) | EP3886914B1 (hu) |
| JP (1) | JP7389803B2 (hu) |
| KR (1) | KR20210098488A (hu) |
| CN (1) | CN113453725A (hu) |
| AU (1) | AU2019386945A1 (hu) |
| BR (1) | BR112021010060B1 (hu) |
| CA (1) | CA3121131A1 (hu) |
| CY (1) | CY1126075T1 (hu) |
| DK (1) | DK3886914T3 (hu) |
| EA (1) | EA202191518A1 (hu) |
| ES (1) | ES2943474T3 (hu) |
| FI (1) | FI3886914T3 (hu) |
| HR (1) | HRP20230500T1 (hu) |
| HU (1) | HUE062089T2 (hu) |
| IL (1) | IL283576B2 (hu) |
| LT (1) | LT3886914T (hu) |
| MX (1) | MX2021005874A (hu) |
| PL (1) | PL3886914T3 (hu) |
| PT (1) | PT3886914T (hu) |
| RS (1) | RS64205B1 (hu) |
| SG (1) | SG11202105565UA (hu) |
| SI (1) | SI3886914T1 (hu) |
| WO (1) | WO2020112588A1 (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017292934B2 (en) | 2016-07-07 | 2024-04-04 | Bolt Biotherapeutics, Inc. | Antibody adjuvant conjugates |
| WO2020190725A1 (en) | 2019-03-15 | 2020-09-24 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting her2 |
Family Cites Families (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| JP3207429B2 (ja) | 1994-08-23 | 2001-09-10 | 株式会社ディ・ディ・エス研究所 | 蛋白質の修飾方法 |
| EP1151299A4 (en) | 1999-01-22 | 2003-06-04 | Smithkline Beecham Corp | PROCESS OF LOCATION-SPECIFIC MARKING OF PROTEINS AND APPLICATIONS |
| JP4118462B2 (ja) | 1999-07-19 | 2008-07-16 | 株式会社リコー | 携帯電子機器 |
| CA2589418A1 (en) | 1999-08-24 | 2001-03-01 | Medarex, Inc. | Human ctla-4 antibodies and their uses |
| NZ534174A (en) | 2002-01-09 | 2007-03-30 | Medarex Inc | An isolated human monoclonal antibody which binds to human CD30 |
| KR101424624B1 (ko) | 2003-05-14 | 2014-07-31 | 이뮤노젠 아이엔씨 | 약물 콘쥬게이트 조성물 |
| US20070184537A1 (en) | 2003-06-03 | 2007-08-09 | Paul Scherrer Institut | Method for the linkage of bifunctional chelating agents and (radioactive) transition metal complexes to proteins and peptides |
| EP1648510B1 (en) | 2003-07-22 | 2013-06-19 | Bayer Pharma Aktiengesellschaft | Rg1 antibodies and uses thereof |
| ZA200603619B (en) | 2003-11-06 | 2008-10-29 | Seattle Genetics Inc | Monomethylvaline compounds capable of conjugation to ligands |
| CN102838675B (zh) | 2003-12-10 | 2014-07-30 | 梅达雷克斯有限责任公司 | Ip-10抗体及其用途 |
| JP5064037B2 (ja) | 2004-02-23 | 2012-10-31 | ジェネンテック， インコーポレイテッド | 複素環式自壊的リンカーおよび結合体 |
| AU2005227326B2 (en) | 2004-03-24 | 2009-12-03 | Xencor, Inc. | Immunoglobulin variants outside the Fc region |
| US7778814B2 (en) | 2004-03-30 | 2010-08-17 | Siemens Aktiengesellschaft | Method and device for simulating an automation system |
| CA2598454C (en) | 2005-02-18 | 2013-04-09 | Medarex, Inc. | Monoclonal antibodies against prostate specific membrane antigen (psma) lacking in fucosyl residues |
| DK1851250T3 (da) | 2005-02-18 | 2012-07-09 | Medarex Inc | Humant monoklonalt antistof mod prostataspecifikt membranantigen (psma) |
| DK2161336T4 (en) | 2005-05-09 | 2017-04-24 | Ono Pharmaceutical Co | Human monoclonal antibodies for programmed death 1 (PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapies |
| AU2006262232A1 (en) | 2005-06-20 | 2007-01-04 | Medarex, Inc. | CD19 antibodies and their uses |
| AU2006265108C1 (en) | 2005-07-01 | 2013-01-17 | E. R. Squibb & Sons, L.L.C. | Human monoclonal antibodies to programmed death ligand 1 (PD-L1) |
| EP1934261B1 (en) | 2005-09-26 | 2014-10-29 | Medarex, L.L.C. | Human monoclonal antibodies to cd70 |
| WO2007038868A2 (en) | 2005-10-03 | 2007-04-12 | The University Of British Columbia | Novel enediyne compound and uses thereof |
| CN103204931B (zh) | 2005-12-08 | 2016-08-03 | 米德列斯公司 | 抗岩藻糖基-gm1的人单克隆抗体及使用抗岩藻糖基-gm1抗体的方法 |
| NZ568015A (en) | 2005-12-08 | 2012-03-30 | Medarex Inc | Human monoclonal antibodies to O8E |
| EP1957539B1 (en) | 2005-12-08 | 2013-04-17 | Medarex, Inc. | Human monoclonal antibodies to protein tyrosine kinase 7 (ptk7) and their use |
| AR061181A1 (es) | 2006-05-25 | 2008-08-13 | Bristol Myers Squibb Co | Compuestos de aziridinil-epotilona |
| PE20080102A1 (es) | 2006-05-25 | 2008-02-11 | Bristol Myers Squibb Co | Conjugados de analogos de aziridinil-epotilona y composiciones farmaceuticas que comprenden los mismos |
| PL2486941T3 (pl) | 2006-10-02 | 2017-08-31 | E. R. Squibb & Sons, L.L.C. | Przeciwciała ludzkie wiążące cxcr4 i ich wykorzystanie |
| TWI447124B (zh) | 2006-12-01 | 2014-08-01 | Medarex Llc | 結合ｃｄ２２的人類抗體與其應用 |
| UY30776A1 (es) | 2006-12-21 | 2008-07-03 | Medarex Inc | Anticuerpos cd44 |
| TWI412367B (zh) | 2006-12-28 | 2013-10-21 | Medarex Llc | 化學鏈接劑與可裂解基質以及其之綴合物 |
| KR101570252B1 (ko) | 2007-07-17 | 2015-11-19 | 메다렉스, 엘.엘.시. | 글리피칸-3에 대한 단클론 항체 |
| WO2009026274A1 (en) | 2007-08-22 | 2009-02-26 | Medarex, Inc. | Site-specific attachment of drugs or other agents to engineered antibodies with c-terminal extensions |
| CA2700860C (en) | 2007-10-01 | 2016-07-19 | Jonathan A. Terrett | Human antibodies that bind mesothelin, and uses thereof |
| US20110184147A1 (en) | 2008-07-04 | 2011-07-28 | Kyushu University, National University Corporation | Enzyme substrate for labeling of protein |
| US8394922B2 (en) | 2009-08-03 | 2013-03-12 | Medarex, Inc. | Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof |
| BR112012026410B8 (pt) | 2010-04-15 | 2023-01-31 | Spirogen Dev Sarl | Composto e conjugado de pirrolobenzodiazepinas e usos dos mesmos |
| JP5870400B2 (ja) | 2010-04-15 | 2016-03-01 | シアトル ジェネティクス，インコーポレーテッド | 標的化ピロロベンゾジアゼピンコンジュゲート |
| CA2930801C (en) | 2010-11-05 | 2019-05-28 | Rinat Neuroscience Corporation | Engineered polypeptide conjugates and methods for making thereof using transglutaminase |
| US8852599B2 (en) | 2011-05-26 | 2014-10-07 | Bristol-Myers Squibb Company | Immunoconjugates, compositions for making them, and methods of making and use |
| KR101860174B1 (ko) | 2011-09-20 | 2018-05-21 | 메디뮨 리미티드 | 표적 접합체 내의 내포를 위한 비대칭 이량체 pbd 화합물로서 피롤로벤조디아제핀 |
| AU2012356894B2 (en) | 2011-12-23 | 2018-01-18 | Innate Pharma | Enzymatic conjugation of polypeptides |
| WO2013122823A1 (en) | 2012-02-13 | 2013-08-22 | Bristol-Myers Squibb Company | Enediyne compounds, conjugates thereof, and uses and methods therefor |
| WO2013181076A1 (en) | 2012-05-30 | 2013-12-05 | University Of Massachusetts Medical School | Coated up-conversion nanoparticles |
| EP2916872B1 (en) | 2012-11-09 | 2019-02-27 | Innate Pharma | Recognition tags for tgase-mediated conjugation |
| DK2956173T3 (en) | 2013-02-14 | 2017-07-17 | Bristol Myers Squibb Co | TUBULYSIS RELATIONSHIPS, METHODS OF PRODUCING AND USING THEREOF |
| US10071169B2 (en) | 2013-06-20 | 2018-09-11 | Innate Pharma | Enzymatic conjugation of polypeptides |
| JP6744212B2 (ja) | 2013-06-21 | 2020-08-19 | イナート・ファルマ・ソシエテ・アノニムＩｎｎａｔｅ Ｐｈａｒｍａ Ｐｈａｒｍａ Ｓ．Ａ． | ポリペプチドの酵素的結合 |
| CA2919583C (en) | 2013-07-31 | 2018-09-11 | Rinat Neuroscience Corp. | Engineered polypeptide conjugates |
| EA201690388A1 (ru) | 2013-08-14 | 2016-07-29 | Уильям Марш Райс Юниверсити | Новые производные унциаламицина, способы их синтеза и их применение в качестве противоопухолевых агентов |
| CN106459981A (zh) | 2013-12-23 | 2017-02-22 | 酵活有限公司 | 包含c端轻链多肽延伸的抗体和缀合物及其使用方法 |
| CA2973354A1 (en) | 2015-01-14 | 2016-07-21 | Bristol-Myers Squibb Company | Benzodiazepine dimers, conjugates thereof, and methods of making and using |
| PE20171185A1 (es) | 2015-01-14 | 2017-08-22 | Bristol Myers Squibb Co | Dimeros de benzodiazepina unidos con puentes de heteroarileno, conjugados de estos, y sus metodos de preparacion y uso |
| WO2016144608A1 (en) * | 2015-03-10 | 2016-09-15 | Bristol-Myers Squibb Company | Antibodies conjugatable by transglutaminase and conjugates made therefrom |
| WO2016209951A1 (en) | 2015-06-23 | 2016-12-29 | Bristol-Myers Squibb Company | Macrocyclic benzodiazepine dimers, conjugates thereof, preparation and uses |
| JP7008014B2 (ja) * | 2015-08-07 | 2022-02-10 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 有効な部位特異的バイオコンジュゲーションのためのトランスグルタミンタグ |
| US20180265851A1 (en) | 2015-10-02 | 2018-09-20 | Bristol-Myers Squibb Company | Transglutaminase variants for conjugating antibodies |
| JP7023933B2 (ja) | 2016-08-19 | 2022-02-22 | ブリストル－マイヤーズ スクイブ カンパニー | セコ－シクロプロパピロロインドール化合物、その抗体－薬物コンジュゲート、ならびに製造および使用方法 |
| US10472361B2 (en) | 2017-08-16 | 2019-11-12 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor |
| US10457681B2 (en) | 2017-08-16 | 2019-10-29 | Bristol_Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor |
| US10508115B2 (en) | 2017-08-16 | 2019-12-17 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor |
| US10494370B2 (en) | 2017-08-16 | 2019-12-03 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses therefor |
| US10487084B2 (en) | 2017-08-16 | 2019-11-26 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor |
-
2019
- 2019-11-25 EP EP19821395.1A patent/EP3886914B1/en active Active
- 2019-11-25 PL PL19821395.1T patent/PL3886914T3/pl unknown
- 2019-11-25 JP JP2021531116A patent/JP7389803B2/ja active Active
- 2019-11-25 SG SG11202105565UA patent/SG11202105565UA/en unknown
- 2019-11-25 EA EA202191518A patent/EA202191518A1/ru unknown
- 2019-11-25 AU AU2019386945A patent/AU2019386945A1/en active Pending
- 2019-11-25 RS RS20230387A patent/RS64205B1/sr unknown
- 2019-11-25 FI FIEP19821395.1T patent/FI3886914T3/fi active
- 2019-11-25 LT LTEPPCT/US2019/062913T patent/LT3886914T/lt unknown
- 2019-11-25 DK DK19821395.1T patent/DK3886914T3/da active
- 2019-11-25 HR HRP20230500TT patent/HRP20230500T1/hr unknown
- 2019-11-25 ES ES19821395T patent/ES2943474T3/es active Active
- 2019-11-25 KR KR1020217019843A patent/KR20210098488A/ko unknown
- 2019-11-25 MX MX2021005874A patent/MX2021005874A/es unknown
- 2019-11-25 US US17/297,796 patent/US20220016260A1/en active Pending
- 2019-11-25 HU HUE19821395A patent/HUE062089T2/hu unknown
- 2019-11-25 WO PCT/US2019/062913 patent/WO2020112588A1/en active Application Filing
- 2019-11-25 CA CA3121131A patent/CA3121131A1/en active Pending
- 2019-11-25 PT PT198213951T patent/PT3886914T/pt unknown
- 2019-11-25 CN CN201980078228.3A patent/CN113453725A/zh active Pending
- 2019-11-25 SI SI201930508T patent/SI3886914T1/sl unknown
- 2019-11-25 BR BR112021010060-1A patent/BR112021010060B1/pt active IP Right Grant
-
2021
- 2021-05-30 IL IL283576A patent/IL283576B2/en unknown
-
2023
- 2023-06-02 CY CY20231100264T patent/CY1126075T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK3886914T3 (da) | 2023-07-03 |
| CY1126075T1 (el) | 2023-11-15 |
| EA202191518A1 (ru) | 2021-10-04 |
| HRP20230500T1 (hr) | 2023-07-21 |
| JP2022513686A (ja) | 2022-02-09 |
| ES2943474T3 (es) | 2023-06-13 |
| IL283576B2 (en) | 2023-07-01 |
| IL283576B1 (en) | 2023-03-01 |
| LT3886914T (lt) | 2023-05-25 |
| MX2021005874A (es) | 2021-07-16 |
| KR20210098488A (ko) | 2021-08-10 |
| IL283576A (en) | 2021-07-29 |
| AU2019386945A1 (en) | 2021-07-22 |
| RS64205B1 (sr) | 2023-06-30 |
| SI3886914T1 (sl) | 2023-06-30 |
| PL3886914T3 (pl) | 2023-05-08 |
| EP3886914A1 (en) | 2021-10-06 |
| SG11202105565UA (en) | 2021-06-29 |
| FI3886914T3 (fi) | 2023-05-26 |
| PT3886914T (pt) | 2023-05-05 |
| WO2020112588A1 (en) | 2020-06-04 |
| CA3121131A1 (en) | 2020-06-04 |
| CN113453725A (zh) | 2021-09-28 |
| EP3886914B1 (en) | 2023-03-29 |
| BR112021010060B1 (pt) | 2024-03-12 |
| US20220016260A1 (en) | 2022-01-20 |
| BR112021010060A2 (pt) | 2021-08-24 |
| JP7389803B2 (ja) | 2023-11-30 |
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