HUE061615T2 - Foszfoinozitid-3-kináz gátlószereit és második antiproliferatív hatóanyagot tartalmazó készítmények - Google Patents

Foszfoinozitid-3-kináz gátlószereit és második antiproliferatív hatóanyagot tartalmazó készítmények

Info

Publication number
HUE061615T2
HUE061615T2 HUE16756763A HUE16756763A HUE061615T2 HU E061615 T2 HUE061615 T2 HU E061615T2 HU E16756763 A HUE16756763 A HU E16756763A HU E16756763 A HUE16756763 A HU E16756763A HU E061615 T2 HUE061615 T2 HU E061615T2
Authority
HU
Hungary
Prior art keywords
kinase inhibitors
preparations containing
antiproliferative agent
phosphoinositide
containing phosphoinositide
Prior art date
Application number
HUE16756763A
Other languages
English (en)
Hungarian (hu)
Inventor
Stephen Joseph Shuttleworth
Andrew David Whale
Original Assignee
Convalife Shanghai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Convalife Shanghai Co Ltd filed Critical Convalife Shanghai Co Ltd
Publication of HUE061615T2 publication Critical patent/HUE061615T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HUE16756763A 2015-08-19 2016-08-19 Foszfoinozitid-3-kináz gátlószereit és második antiproliferatív hatóanyagot tartalmazó készítmények HUE061615T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1514760.6A GB201514760D0 (en) 2015-08-19 2015-08-19 Compounds and method of use

Publications (1)

Publication Number Publication Date
HUE061615T2 true HUE061615T2 (hu) 2023-07-28

Family

ID=54258859

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16756763A HUE061615T2 (hu) 2015-08-19 2016-08-19 Foszfoinozitid-3-kináz gátlószereit és második antiproliferatív hatóanyagot tartalmazó készítmények

Country Status (22)

Country Link
US (3) US10668077B2 (OSRAM)
EP (1) EP3337477B1 (OSRAM)
JP (1) JP2018523689A (OSRAM)
KR (1) KR20180064387A (OSRAM)
CN (2) CN113786409B (OSRAM)
AU (1) AU2016307885B2 (OSRAM)
CA (1) CA2995898A1 (OSRAM)
DK (1) DK3337477T3 (OSRAM)
ES (1) ES2939815T3 (OSRAM)
FI (1) FI3337477T3 (OSRAM)
GB (1) GB201514760D0 (OSRAM)
HR (1) HRP20230376T1 (OSRAM)
HU (1) HUE061615T2 (OSRAM)
IL (1) IL257499A (OSRAM)
LT (1) LT3337477T (OSRAM)
MX (1) MX2018001926A (OSRAM)
PL (1) PL3337477T3 (OSRAM)
PT (1) PT3337477T (OSRAM)
RS (1) RS64095B1 (OSRAM)
SI (1) SI3337477T1 (OSRAM)
SM (1) SMT202300063T1 (OSRAM)
WO (1) WO2017029517A1 (OSRAM)

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GB201514754D0 (en) 2015-08-19 2015-09-30 Karus Therapeutics Ltd Compounds
GB201514760D0 (en) 2015-08-19 2015-09-30 Karus Therapeutics Ltd Compounds and method of use
GB201514758D0 (en) 2015-08-19 2015-09-30 Karus Therapeutics Ltd Formulation
GB201514751D0 (en) 2015-08-19 2015-09-30 Karus Therapeutics Ltd Compounds
WO2020055840A1 (en) * 2018-09-11 2020-03-19 Curis Inc. Combination therapy with a phosphoinositide 3-kinase inhibitor with a zinc binding moiety
CA3113408A1 (en) * 2018-09-18 2020-03-26 Kabushiki Kaisha Yakult Honsha Cancer combination therapy using quinoline carboxamide derivative
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CN111904958B (zh) * 2019-05-09 2022-09-13 浙江大学 Umi-77作为线粒体自噬诱导剂在制备治疗炎症及神经退行性疾病药物中的应用
GB201909468D0 (en) * 2019-07-01 2019-08-14 Karus Therapeutics Ltd Compounds for treating cancer
CN114533879B (zh) * 2020-11-19 2023-09-29 广州顺健生物医药科技有限公司 治疗癌症的联合疗法

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Also Published As

Publication number Publication date
DK3337477T3 (en) 2023-02-20
US11291669B2 (en) 2022-04-05
US10668077B2 (en) 2020-06-02
GB201514760D0 (en) 2015-09-30
US20210069200A1 (en) 2021-03-11
ES2939815T3 (es) 2023-04-27
CN113786409B (zh) 2024-04-02
HK1251467A1 (en) 2019-02-01
MX2018001926A (es) 2018-06-19
HRP20230376T1 (hr) 2023-06-23
WO2017029517A1 (en) 2017-02-23
SMT202300063T1 (it) 2023-03-17
AU2016307885B2 (en) 2019-07-25
FI3337477T3 (fi) 2023-04-27
KR20180064387A (ko) 2018-06-14
CN108348505A (zh) 2018-07-31
CA2995898A1 (en) 2017-02-23
SI3337477T1 (sl) 2023-04-28
LT3337477T (lt) 2023-03-10
US20180243313A1 (en) 2018-08-30
IL257499A (en) 2018-07-31
EP3337477B1 (en) 2023-02-01
RS64095B1 (sr) 2023-04-28
CN113786409A (zh) 2021-12-14
CN108348505B (zh) 2021-10-12
PL3337477T3 (pl) 2023-07-03
JP2018523689A (ja) 2018-08-23
PT3337477T (pt) 2023-03-20
EP3337477A1 (en) 2018-06-27
US12257254B2 (en) 2025-03-25
US20230066999A1 (en) 2023-03-02
AU2016307885A1 (en) 2018-03-08

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